E-Supplement 1. Clinical Characteristics of Bilateral Duane Syndrome in 16 Patients: Type

e-Supplement 1. Clinical characteristics of bilateral Duane syndrome in 16 patients: Type (Huber’s classification), ocular limitation, horizontal and vertical strabismus, abnormal head position, upshoot or downshoot, alphabetic syndrome, stereoacuity, Jampolsky’s classification.

Other UpS V Cases T Major lim Sym H St AHP Vert St AS STA Jp HL DnS lim Abd 1 I/I 0 1 ortho 0 0 0 X Yes 0 3 OD/OS AbdOD Add OD ++ XT OD hyperT Up 2 III/III 0 R 0 V Yes 3 Abd OS AddOS 2° OD Dn ++ Add OD AddOS hypoT 3 II/III 0 XT 20° L UpS V No 0 2 Abd OS ++ OD Add Abd 4 I/I OD/OS 0 XT 14° R 0 0 V No Up 2 OD>OS + Abd ET OS hypoT 5 I/III Add OS 0 R 10° 0 V Yes Up 3 OD>OS 4° OS Abd 6 I/I 0 1 ortho 0 0 0 0 0 1 OD/OS Abd 7 I/I 0 1 ortho 0 0 0 0 0 1 OD/OS Add Abd ET OD hypoT 8 I/I OD/OS 0 R V No 2 OD>OS 6°/12° OD + Add XT OS 9 II/II 0 0 L variable DnS A No Up 2 OS>OD 24° Add Abd ET OD hypoT 10 I/I OD/OS 1 0 0 V Yes 0 3 OD/OS 6°/8° OS + Abd ET OS 11 I/I 0 0 R 30° UpS V No 0 2 OS>OD 40° Add Abd 12 I/I OD/OS 1 ortho 0 0 0 0 Yes 0 1 OD>OS + Add Abd ET OS hyperT 13 I/I OD/OS 0 0 UpS V Yes Up 3 OD>OS 2° OD + Add Abd ET OD 14 I/I OD/OS 0 R 0 0 0 Yes 0 1 OD>OS 2°/4° + Abd ET OD hypoT 15 I/I 0 1 0 0 A 0 2 OD/OS 16°/18° OD Abd ET OD 16 I/I 0 0 R 15° 0 0 0 0 2 OD>OS 4°

T, type; OD, right eye; OS, left eye; Major lim, major horizontal ocular limitation; Other HL, other horizontal ocular limitation; Abd, abduction; Add, adduction; Sym, symmetry of limitations between the two eyes; H St, horizontal strabismus; ET, esotropia; XT, exotropia; ortho, orthotropic; AHP, abnormal head position; R, right; L, left; Vert St, vertical strabismus; hypoT, hypotropia; hyperT, hypertropia; UpS, upshoot; DnS, downshoot; AS, alphabetic syndrome; STA, normal stereoacuity; V lim, vertical limitation; Dn, down; Jp, Jampolsky’s classification (1, DRS with fusion; 2, DRS without fusion; 3, Alphabetic syndrome).