African Horse Sickness s1

OIE Collaborating Centre Reports

Activities in 2012

Title of Collaborating Centre: Laboratory Capacity Building

Address of Collaborating Centre: Australian Animal Health Laboratory Geelong, Victoria 3220, Australia

Tel.: (61 3) 5227 5000

Fax: (61 3) 5227 5555

e-mail address: [email protected]

website: www.csiro.au

Name of Director of Institute Professor Kurt Zuelke (Responsible Official):

Name (including Title and Dr Peter Daniels Position) of Head of the Collaborating Centre (formally OIE Contact Point):

Name (including Title and Dr Peter Daniels Position) of writer of this report (if different from above)

Annual reports of OIE Reference Centres, 2012 1 Laboratory Capacity Building

Summary of activities specifically related to the mandate of OIE Collaborating Centres

1. Activities as a centre of research, expertise, standardisation and dissemination of techniques within the remit of the mandate given by the OIE

The AAHL Regional Program in the Asia Pacific seeks to contribute to a prosperous and stable world through support to food security and One Health initiatives in the region. A coordinated approach to veterinary laboratory capacity development across national boundaries is being developed in the Southeast Asian region in collaboration with the regional offices of the OIE and the FAO as well their country offices.

Together with donor agencies and the international organizations, the OIE and the FAO, AAHL is particularly focusing in helping to develop laboratory networks. These may be in individual countries, where the work AAHL undertakes separately in Australia, provides a useful model and experience, and across countries in the region. As well as addressing strategic and technical issues such as laboratory management and support to quality assurance AAHL has been developing systems of networked data management.

An activity incorporating many of these various aspects has been a project developing laboratory capacity for bioinformatics of HPAI and the development of antigenic cartography for monitoring of the antigenic match of vaccines to circulating field strains in Indonesia. The emphasis has been on developing capacity in Indonesian government institutions for sequence analysis for molecular epidemiology, in screening of antigenic profiles of H5N1 isolates and then further characterization of antigenicity for antigenic cartography analyses. The data handling needs were addressed.

AAHL has also been working with the regional offices of FAO and OIE in Bangkok to deliver specific outcomes such as those supported by the IDENTIFY initiative, that progress and harmonize regional activities developing capacity for emerging infectious disease preparedness.

The OIE Twinning Project with the Malaysian Veterinary Research Institute (VRI) at Ipoh for avian influenza and Newcastle disease has continued with elements of technology transfer, development of management systems such as for quality assurance and biorisk management, and the training of the partnered laboratory to deliver proficiency testing to its laboratories nationally.

The One Health project in the Laos PDR, Increased Productivity and Reduced Risk in Pig Production and Market Chains. Component 1: Animal and Human Health continues implementation, interacting with village based smallholder market chains, providing animal health capacity building in the field and also to the Laos PDR national veterinary laboratory.

AAHL is specifically continuing its work in developing laboratory capacity with the Indonesian government network of laboratories, continuing development of laboratory capacity for HPAI in particular and also addressing a range of zoonoses such as rabies, anthrax and brucellosis. Importantly the laboratory component is within the context of helping the animal health authorities to update systems for prioritising and managing animal health issues more broadly, and so has a management systems element. This link between policy setting and laboratory function in a strategic sense is seen as most important in all laboratory capacity building.

2. Proposal or development of any procedure that will facilitate harmonisation of international regulations applicable to the surveillance and control of animal diseases, food safety or animal welfare

Through OIE and FAO Regional Offices servicing the ASEAN region AAHL continues to assist in the development of initiatives to harmonize veterinary laboratory testing for emerging infectious and zoonotic diseases. Training in systems to improve the strategic planning of laboratory activities within the animal health sector operations are being delivered, as well as management systems that help laboratories further develop their capability in diagnostic technologies, quality assurance systems and laboratory biorisk management.

2 Annual reports of OIE Reference Centres, 2012 Laboratory Capacity Building

3. Networking

a) Maintenance of a network with other OIE Collaborating Centres designated for the same specialty, and

AAHL participates in the OFFLU Technical Activity for laboratory capacity building.

b) Should the need arise, maintenance of a network with Collaborating Centres in other disciplines

AAHL participates on the OFFLU activity to generate and analyse data relating to animal influenza for the WHO VCM process, collaborating with other OIE collaborating centres and reference laboratories and with designated WCO Collaborating Centres for Influenza.

4. Placement of expert consultants at the disposal of the OIE

 Chris Morrissy conducted a laboratory accreditation audit to the ISO/IEC17025:2005 standard of the Hong Kong laboratory for the accrediting authority NATA, Hong Kong, 9-13 January 2012  Chris Morrissy facilitated and participated in a meeting to create a workshop on Laboratory Networking and Proficiency Testing for priority HPEDs in SAARC countries in Bangladesh, 21-26 January 2012  Chris Morrissy contributed to the 4 Way Linking meeting as an OIE representative in Vietnam, 14 February 2012  Peter Daniels chaired the OIE ad hoc Group meeting on Biosafety and Biosecurity in Veterinary Laboratories, OIE HQ, Paris, 9-16 February 2012  Frank Wong attended the 2nd OFFLU Swine Influenza Technical Activity Meeting at OIE HQ, Paris, 25-31 March 2012  Peter Daniels attended and presented at the Asia pacific Biosafety Association (A-PBA) Scientific Conference: Asia-Pacific Biosafety – Moving Toward One World Health, Indonesia, 24-28 April 2012  Wilna Vosloo presented a talk at the Second Global Conference on FMD Control organized by OIE and FAO and participated in the FMD Vaccine Expert Advisory Group, Thailand 23-30 June 2012  Paul Selleck participated for FAO in an international mission to Pakistan to establish a Crisis Management Centre in Animal Health, focusing on NDV, Pakistan, 7-18 Jul 2012  Peter Daniels chaired the Meeting of the ad hoc Group on Biosafety and Biosecurity in Veterinary laboratories at OIE Headquarters, France 14-21 July 2012  Chris Morrissy contributed to the OIE/FAO meeting on HPAI, Thailand, 16-18 July 2012  Chris Morrissy and Noel Ritson-Bennett conducted a scoping mission for the Laboratory-Field Epidemiology Linkage training under the FAO Biosafety Training Project, Thailand, 22-28 July 2012  Chris Morrissy attended the Laboratory TAG meeting, Thailand, 30-31 July 2012  Peter Daniels participated in the OIE training workshop for OIE National Focal Points on Laboratories, delivering a presentation on Biosafety and Biosecurity in compliance with OIE Standards, 19-24 August 2012  Andrew Hill contributed to the ASEAN workshop on Preparedness and response to a Biological Event, Philippines, 4-8 September 2012  Peter Daniels attended the meeting of the OIE Biological Standards Commission, France 9-17 September 2012  Martyn Jeggo was an invited speaker at the IAEA Scientific Forum on Nuclear Application related to Food Production, Protection and Safety, Austria, 16-22 September 2012  Chris Morrissy attended the Fourth Laboratory Directors Forum Meeting which was hosted by the Department of Animal Health in collaboration with OIE and FAO, Nha Trang, Vietnam, 10-11 October 2012  Chris Morrissy participated in the 7th SEACFMD Labnet Meeting in Lanzhou, China, 15-17 October 2012  Frank Wong was invited by the FAO Animal Health Division (AGAH) as a representative to join an expert consultation for establishing and maintaining core facilities for molecular test diagnosis in veterinary laboratories of developing countries with limited resources, Austria, 14-21 October 2012.  James Watson conducted a laboratory accreditation audit on behalf of the International Accreditation New Zealand (IANZ), Wellington, New Zealand, 15-18 October 2012  Peter Daniels attended the Influenza Risk Assessment and Risk Modelling: Pandemic Influenza Threats and Beyond as OFFLU representative, Rome, 7-9 November 2012

 Peter Daniels was invited to present at the 15th AAAP (Asian-Australasian Association of Animal Production Societies) Symposium, Thailand, 25-27 November 2012, instructing in improved approaches for surveillance  Peter Daniels contributed to the Third Regional Workshop on Multi-Sectoral Collaboration on Zoonoses Prevention and Control: Leading the Way on One Health, Bali, Indonesia, 27-29 November 2012  Chris Morrissy was participated as an OIE expert in the Four Way Linking Project, Indonesia, 1-14 December 2012  Wilna Vosloo attended the meeting of the OIE ad hoc Group on the Evaluation of Food and Mouth Disease (FMD) Status of Member Countries to continue with the review of the FMD Chapter in the Terrestrial Manual and evaluate dossiers of 6 countries who are applying for disease status, France 7-15 December 2012  Peter Daniels participated in an OIE ad hoc Working Group on New Approaches to Diagnosis: Applied Genomics at the OIE, France 9-13 December 2012

5. Provision of scientific and technical training, within the remit of the mandate given by the OIE, to personnel from OIE Member Countries

 The following training was conducted in member countries:

Training given to member countries under OFFLU, EPT and EPT+ programs administered by the OIE and FAO:  Paul Selleck provided training under the OFFLU LOA 3 (managed by FAO) to Putsvetma, Wates and DIC Denpasar laboratories in Indonesia, 7 January to 4 February 2012  Peter Durr and Kerryn Graham travelled to Luang Prabang, Vientiane and Bali under the OFFLU LIMS project to facilitate data meeting and conduct results analysis, Laos 22 January-4 February 2012  Peter Durr facilitated the inception workshop under the OFFLU AI Indonesia project, 1-11 February 2012  Chris Morrissy and Rod Howard travelled to Bhopal to visit HSADL under the FAO Technical Support for Biosafety and Laboratory Training PR48078 to contribute to laboratory management capacities particularly in Biosafety equipment maintenance, India, 14-20 April 2012  Mai Hlaing Loh, Shane Riddell and Chris Morrissy conducted regional training on proficiency testing at the project directorate IVRI on foot and mouth disease at the Indian Veterinary Institute (IVRI) in Mukteswar, India, 14-26 May 2012  Andrea Certoma and Antonio Di Rubbo conducted a training workshop under the FAO Multi Disease Project, Thailand 2-17 August 2012  Chris Morrissy, Susan Juzva and Brian Meehan established harmonized diagnostic protocols to key animal health laboratories in SE Asia for the diagnosis of PRRS/CSF under the FAO Multi Disease Project, Thailand 2-31 August 2012  Chris Morrissy travelled under the FAO Multi Disease Project to visit laboratories in Lampung, Subang, Wates and Medan.  He will also attend the FAO Avian Influenza Coordination Meeting in Wates , Indonesia 3-24 November 2012  Andrea Certoma travelled to Myanmar, Cambodia, Malaysia, Vietnam, Philippines and Thailand to conduct back stopping missions under the FAO Multi Disease project, 7 November to 15 December 2012  John Allen and Peter Durr attended an FAO Avian influenza Virus Coordination meeting, Indonesia, 19-20 November 2012

As indicated in Section 1 of this report, the AusAID funded Australia Indonesia Partnership for Emerging Infectious Diseases Animal Health Program 2010-2014 (AIP-EID) is currently a major capacity building activity for AAHL, working with the national network of veterinary laboratories in Indonesia and the central veterinary authority. The laboratories in the network comprise diagnostic laboratories, the national veterinary research laboratory and major reference centre, a laboratory for the manufacture of vaccines and diagnostics and the national veterinary assay laboratory supporting the regulation of veterinary pharmaceuticals and vaccines. Hence this is a major capacity building activity with the emphasis on developing networked capability. The overall project is managed by the Department of Agriculture, Fisheries and Forestry (DAFF), Australia’s national veterinary authority.  A major activity required under the AIP EID Project has been an Indonesian Laboratory Review. John Allen was a member of the review team and helped conduct the first stage in Indonesia, 11-29 March 2012. John participated in the second stage, 29 April to 16 May 2012  John Allen also conducted project sub-committee meetings and project meetings 8-18 February and 10-21 September 2012

 John Allen chaired the Reflections Workshop required under the Project, 1-12 October 2012  Paul Selleck and John Allen travelled to PUTSVETMA to conduct a gap analysis of that institution under the Project, 6-12 October 2012.

With respect to rabies training under the AIP EID Project  John Allen commenced scoping visits for future Rabies training, Indonesia 8-18 February 2012  Andrea Certoma conducted a scoping visit to Bukittinggi for a future Rabies Training course under the Project, Indonesia, 13-16 February 2012  Andrea Certoma conducted a Rabies workshop in Bukittinggi under the DAFF AIP EID Project, Indonesia 20 April to 19 May 2012  Jemma Bergfeld travelled to assist in the delivery of the rabies Workshop held in Bukittinggi 5-19 May 2012  Andrea Certoma and Mai Hliang Loh attended the Bukittinggi Laboratory to conduct follow-up training for Rabies diagnosis and interpretation of statistical and PT results, 7-22 September 2012

With respect to brucella training under the AIP EID Project  Susan Juzva and Trevor Taylor conducted a scoping visit to Makassar for a Brucella Training course, 13-22 February 2012  Trevor Taylor travelled to Makassar to deliver reagents and cultures required for the Brucella Workshop, 3-9 April 2012  Susan Juzva, Shane Riddell and Trevor Taylor conducted the Brucella workshop in Makassar 10-28 April 2012  John Allen helped facilitate the Brucella Workshop in Makassar 14-19 April 2012  Ross Lunt and Mai Hliang Loh attended the Makassar Laboratory to conduct follow-up training for Brucella diagnosis and interpretation of statistical and PT results, 9-20 September 2012

With respect to anthrax training under the AIP EID Project  John Allen and Trevor Taylor conducted a scoping mission to Wates for Anthrax training, 21-29 November 2012

An important capacity building activity that AAHL is happy to support is the OIE twinning Project in Avian Influenza and Newcastle Disease between AAHL and the Veterinary Research Institute (VRI) at Ipoh in Malaysia:  Chris Morrissy visited VRI under the OIE Twinning Project, Ipoh, Malaysia, 26-29 March 2012 for project work planning consultations for the year  Chris Morrissy and Rod Howard, a senior biorisk management engineer from AAHL, travelled to VRI to assist in consultations on engineering requirements, 22-24 April 2012  Bernadette O’Keefe, the AAHL Quality Assurance Manager, travelled to VRI for follow-up on actions from the Internal Audit report undertaken in July 2011, 30 September to 9 October 2012  Paul Selleck assisted in establishing virus cultures as required under the OIE Twinning Project, Ipoh, Malaysia, 12-19 October 2012

In other capacity building activities for member countries:  Gary Crameri participated in the Chinese Academy of Sciences (CAS) exchange scheme work with the Wuhan Institute of Virology on the development of Chinese bat cell lines project. China, 26 March- 15 April 2012  Jianning Wang attended and presented at the molecular Diagnostic Workshop Program held at the National Centre for Biosecurity and Infectious Disease in Wallaceville, 1-2 May 2012  Debbie Eagles and Trevor Taylor conducted Brucella training for new veterinarians under a request from the Fijian Government, Fiji 11-23 June 2012  Trevor Taylor conducted follow-up support for the recently run Brucella Testing training for the Fijian Government, 26 August to 1 September 2012  Martyn Jeggo and Warren Michell attended a meeting at AMES for training officers to develop strategies on how to collaborate and harmonise the training that is conducted in high containment laboratories, USA, 22- 29 June 12

AAHL is also engaged in capacity building activities with laboratories servicing aquatic animal health needs:  Chris Morrissy facilitated project planning meetings for work to be conducted under an AusAID funded Public Sector Linkages program (PSLP) Project in Vietnam, 16-18 February 2012

 Nicholas Gudkovs attended the first project meeting and to assess current capabilities in AAH diagnosis at RAHO6 and the Central Vietnam Veterinary Institute under the PSLP Vietnam Project, Vietnam 16 February to 8 March 2012  Mark Crane and Nick Gudkovs conducted a workshop under the DAFF Regional PT Program for Aquatic Animal Disease Laboratories in the Asia-Pacific 24-28 July 2012  Nicholas Gudkovs and John Hoad commenced technical visits to provide advice and training in OIE based diagnostics (cell culture/virus isolation and molecular diagnosis) under the PSLP Vietnam project, 17 September to 3 October 2012

Another capacity building activity for aquatic animal health in the region is the provision of proficiency testing for certain major AAH pathogens, with funding from the Australian DAFF. (AAHL is accredited as a proficiency test provider to the international standard ISO/IEC 17043:2010.) This project which is just commencing will run over a number of years.  Nicholas Gudkovs travelled to Thailand under the ASEAN Aquatic Animal Health Proficiency Testing project to collect and prepare yellow head virus (YHV) infected tissue for transfer to AAHL for the development of PT panels, 3-10 October 2012 and to Indonesia to similarly collect and prepare infectious myonecrosis virus (IMNV) and Taura syndrome virus (TSV) viral inocula, 24 November to 7 December 2012

6. Organisation of scientific meetings on behalf of the OIE

AAHL did not specifically host major meetings on capacity building for the OIE during this period but helped plan and participated in capacity building meetings co-organized by OIE and FAO regional offices, with activities as outlined above in sections 4 and 5.

7. Coordination of scientific and technical studies in collaboration with other laboratories, organisations or collaborating centres

The project in the Laos PDR: Increased Productivity and Reduced Risk in Pig Production and Market Chains. Component 1: Animal and Human Health, has substantial components of capacity building for both laboratory and field staff. Project visits in support of this work included:  Dr John Allen travelled to Vientiane for implementation discussions and visits to field sites, 16-28 January 2012 and again 26 February to 2 March 2012  Jemma Bergfeld travelled to Vientiane to service the project field sites, 1-19 April 2012  John Allen returned for a brief implementation visit, 2-7 June 2012, returning 29 July to 6 August 2012 and again from 23-25 October 2012

As indicated in last year’s report, AAHL has commenced an FMD Risk Management Project with the primary aim of evaluation of vaccines contained in the Australian FMD bank using challenge studies. These will be conducted in Vietnam (in pigs), in South Africa (in sheep) and in Argentina (in cattle), with supporting studies being conducted at the OIE FMD Reference Laboratory at Pirbright. Capacity building, particularly in diagnostics and molecular characterization, is an essential component of the studies. During the current year the following activities have been conducted in partner countries:  Chris Morrissy helped establish and initiate the laboratory trials of FMD in pigs at NAVETCO in Vietnam, 4- 11 February 2012  Wilna Vosloo, Jacqui Morris and Negendra Singanallur commenced the experimental infection of pigs and followed up with titration of challenge virus for use in future pig challenge experiments at RAHO6, Vietnam 15 February to 3 March 2012  Wilna Vosloo, Jacqui Morris and Negendra Singanallur continued work on the experimental infection of pigs under at RAHO6, Vietnam, 13 March to 4 April 2012.  Chris Morrissy travelled to Vietnam to assist with the work, 5-7 April 2012  Jacqui Morris, Jianning Wang and Nagendra Singanallur commenced PCR and virus isolation on materials collected during the FMD pig trials at RAHO6, Vietnam 22-28 April 2012  Jacqui Morris, Wilna Vosloo and Nagendra Singanallur continued pig inoculations for the vaccine efficacy studies using 01 Manisa monovalent vaccine in Vietnam, 7-31 May 2012  Nagendra Singanullar returned to Vietnam partner laboratories. This phase included performing the in-vitro assays on samples previously collected, Vietnam 22 July to 25 August 2012  Jacqui Morris continued work in Vietnam with collaborators at NAVETCO, 31 July to 24 August 2012

 Jacqui Morris conducted the second phase of the FMD project to generate pig challenge virus for a serotype A Vietnamese isolate belonging to the MAY/THAI genotype, Vietnam 1-19 October 2012.  Nagendra Singanallur continued work in Vietnam, continuing with the adaptation and titration of this strain in pigs and perform the vaccine efficacy studies using A Malaysia 97, Vietnam, 11 November to 5 December 2012

Under the collaborative project Control and characterisation of highly pathogenic avian influenza strains in poultry in Indonesia funded by ACIAR  Peter Durr continued work with the University of Melbourne in collaboration with Bbalitvet on AI Surveillance in Indonesia, 19 May to 2 June 2012  Peter Durr travelled to Indonesia project activities, 23-30 September 2013 and again 20-27 November 2012

8. Publication and dissemination of any information within the remit of the mandate given by the OIE that may be useful to Member Countries of the OIE

Journal Articles  Conlan, J. V., Vongxay, K., Jarman, R. G., Gibbons, R. V., Lunt, R. A., Fenwick, S., Blacksell, S. D. (2012). Serologic Study of Pig-Associated Viral Zoonoses in Laos. American Journal of Tropical Medicine and Hygiene, 86(6), 1077-1084. doi: 10.4269/ajtmh.2012.11-0195  Daniels, P., Morrissy, C., Poermadjaja, B., Selleck, P., Stratton, J., Allen, J., Kalpravidh, W. (2012). Diagnostic capacity for regional emergency infectious disease preparedness. ACIAR Proceedings Series(137), 83-86.  Daniels, P., Wiyono, A., Sawitri, E., Poermadjaja, B., & Sims, L. (2012). H5N1 highly pathogenic avian influenza in Indonesia: retrospective considerations. Curr Top Microbiol Immunol, online in press, 20.  Foord, A., Middleton, D., & Heine, H. (2012). Hendra virus detection using Loop-Mediated Isothermal Amplification. Vet Microbiol, 181, 93-96.  Henning, J., Wibawa, H., Yulianto, D., Usman, T. B., Junaidi, A., & Meers, J. (2012). The management of smallholder duck flocks in Central Java, Indonesia, and potential hazards promoting the spread of Highly Pathogenic Avian Influenza virus. Worlds Poultry Science Journal, 68(3), 513- 528. doi: 10.1017/s004393391200061x  Hoque, M. A., Skerratt, L. F., Garland, S., Burgess, G. W., & Selleck, P. (2012). Adaptations of a Competitive Enzyme-Linked Immunosorbent Assays for the Detection of Antibodies to Influenza A Virus in Horse Sera for Use in Wild Aquatic Birds. Indian Journal of Virology, 23(3), 261-269. doi: 10.1007/s13337-012-0074-3  Jaramillo, D., Tweedie, A., Becker, J. A., Hyatt, A., Crameri, S., & Whittington, R. J. (2012). A validated quantitative polymerase chain reaction assay for the detection of ranaviruses (Family Iridoviridae) in fish tissue and cell cultures, using EHNV as a model. Aquaculture, 356, 186-192. doi: 10.1016/j.aquaculture.2012.05.017  Kaku, Y., Noguchi, A., Marsh, G. A., Barr, J. A., Okutani, A., Hotta, K., Wang, L.-F. (2012). Antigen capture ELISA system for henipaviruses using polyclonal antibodies obtained by DNA immunization. Arch Virol, 157(8), 1605-1609. doi: 10.1007/s00705-012-1338-3  Kaku, Y., Noguchi, A., Marsh, G. A., Barr, J. A., Okutani, A., Hotta, K., Wang, L.-F. (2012). Second generation of pseudotype-based serum neutralization assay for Nipah virus antibodies: Sensitive and high-throughput analysis utilizing secreted alkaline phosphatase. J Virol Methods, 179(1), 226-232. doi: 10.1016/j.jviromet.2011.11.003  Keeling, S. E., Johnston, C., Wallis, R., Brosnahan, C. L., Gudkovs, N., & McDonald, W. L. (2012). Development and validation of real-time PCR for the detection of Yersinia ruckeri. Journal of Fish Diseases, 35(2), 119-125. doi: 10.1111/j.1365-2761.2011.01327.x  Kumar, A., Wong, A. K. L., Lizard, M. L., Moore, R. J., & Lefevre, C. (2012). miRNA_Targets: A database for miRNA target predictions in coding and non-coding regions of mRNAs. Genomics, 100(6), 352-356. doi: 10.1016/j.ygeno.2012.08.006  Serrao, E., Meers, J., Pym, R., Copland, R., Eagles, D., & Henning, J. (2012). Prevalence and incidence of Newcastle disease and prevalence of Avian Influenza infection of scavenging village chickens in Timor-Leste. Preventive Veterinary Medicine, 104(3-4), 301-308. doi: 10.1016/j.prevetmed.2011.12.018

 Stubbs, S., Oura, C. A. L., Henstock, M., Bowden, T. R., King, D. P., & Tuppurainen, E. S. M. (2012). Validation of a high-throughput real-time polymerase chain reaction assay for the detection of capripoxviral DNA. J Virol Methods, 179(2), 419-422. doi: 10.1016/j.jviromet.2011.11.015  Wang, L.-F., & Daniels, P. (2012). Diagnosis of henipavirus infection: current capabilities and future directions. Curr Top Microbiol Immunol, 359, 179-196. doi: 10.1007/82_2012_215  Wibawa, H., Henning, J., Waluyati, D. E., Usman, T. B., Lowther, S., Bingham, J., Meers, J. (2012). Comparison of serological assays for detecting antibodies in ducks exposed to H5 subtype avian influenza virus. BMC Veterinary Research, 8(117), (23 July 2012)-(2023 July 2012).

Conference Papers  Babiuk, S., Bowden, T., Wallace, D., Mather, A., Gertds, V., & Babiuk, L. (2012). Sheep and goat pox viral diagnostics and vaccine development collaboration. Paper presented at the 11th Annual Meeting of the Canadian Animal Health Laboratorians Network, Winnipeg, Canada.  Bagnara, A., & Lunt, R. (2012). Validation of Equine IgM Capture ELISA for Serodiagnosis of West Nile Virus Infection. Paper presented at the AAVLD Conference, University of Sydney, NSW.  Daniels, P. (2012). Advances in Biomedical Research and Biosecurity: Biorisk management issues in Animal Health Labs (Abstract). Paper presented at the 7th APBA Scientific Conference, Moving Towards One World-One Health, Bali, Indonesia.  Daniels, P. (2012). Emerging and Re-emerging Disease Control. Facing New Challenges: Emerging Pathogens & Disease Surveillance Control (Abstract). Paper presented at the The 7th APBA Scientific Conference, Moving Towards One World-One Health, Bali, Indonesia.  Daniels, P. (2012). The Challenge of Influenza Surveillance in the Intensive Animal Industries, The Joint NHMRC and Bill & Melinda Gates Foundation Forum: H5N1: are we prepared?, 1 November 2012, NHMRC Canberra  Daniels, P. (2012). Animal Health Challenges and Climate Change, 15th AAAP Animal Science Congress, 26-30 November 2012, Thammasat University, Thailand  Daniels, P., Diaz, F., & Hamilton, K. (2012). OIE guidelines and recommendations for biorisk management in veterinary laboratories (Abstract). Paper presented at the The 7th APBA Scientific Conference, Moving Towards One World-One Health, Bali, Indonesia.  Nining Hartaningsih, Mia Kim, Paul Selleck, Frank Wong, James McGrane, Elly Sawitri, Pudjiatmoko, Muhammed Azhar (2012) Sustainable approach to influenza virus monitoring for animal health in Indonesia. 8th International Symposium on Avian Influenza, Royal Holloway, University of London. 1-4 April 2012.  Holmes, C., Crameri, S., & Hyatt, A. (2012). Diagnostic electron microscopy and communications via a high definition interactive communication platform. Paper presented at the The Joint APMC 10/ICONN 2012/MMA22 Conference, Perth, WA.  Juzva, S., Meehan, B., Carlile, G., & Morrissy, C. (2012). Diagnostics for the Detection of CSFV and PRRSV and the Importance of Proficiency Testing. Follow-up to CSFV and PRRSV Workshop (HCMC July 2011). Paper presented at the Veterinary Research Institute Conference, Ipoh, Malaysia.  Juzva, S., Riddell, S., Morrissy, C., & Allen, J. (2012). Diagnostic Serology for the Detection of Brucellosis. Paper presented at the Australia-Indonesia Partnership for Emerging Infectious Diseases - Bovine Brucellosis Diagnostic Training Workshop - DIC Maros, Maros, South Sulawesi, Indonesia.  McNabb, L., Lunt, R., Barr, J., Crameri, G., Juzva, S., & Wang, L. (2012). Developments in Hendra virus serology using Henipavirus binding and blocking assays. Paper presented at the Emerging Infectious Diseases Symposium (EIDS), Geelong.  Mohr, P., Moody, N., & Crane, M. (2012). Real-time PCR limits of detection: can a ct value >40 be positive. Paper presented at the 8th Annual Meeting of the Australian Association of Veterinary Laboratory Diagnosticians, DPI, Victoria, AgriBio Centre, La Trobe University, Bundoora, Vic.  Payne, J., Bergfeld, J., Rookes, J., Bingham, J., & Middleton, D. (2012). Title: Pesky Prions: disease, disinfection and diagnosis. Paper presented at the AIMS National Meeting, Darwin, NT.  Riddell, S., Certoma, A., van der Heide, B., Wong, F., Walker, S., Ha, W., Daniels, P. (2012). Laboratory diagnosis of Hendra virus infection during the 2011 outbreaks in Australia. Paper presented at the 6th Asia Pacific Conference on Medical Virology, Adelaide.  Shan, S. (2012). Avian paramyxovirus serotype 1 (APMV-1) in Australia. Paper presented at the The Asian-Pacific Regional Workshop on Newcastle disease in China, Qingdao, China.  Paul Selleck, Frank Wong, Mia Kim, Nining Hartaningsih, Elly Sawitri, Pudjiatmoko, Muhammad Azhar, Gwenaelle Dauphin, James McGrane, John Allen and Peter Daniels (2012) Monitoring

antigenic variation of H5N1 avian influenza viruses in Indonesia towards improved vaccine selection. 6th International Veterinary Vaccines and Diagnostics Conference, 29 July – 1st August 2012, Cairns, Queensland, Australia  Paul Selleck, Frank Wong, Mia Kim, Nining Hartaningsih, Elly Sawitri, Pudjiatmoko, Muhammad Azhar, Gwenaelle Dauphin, James McGrane, John Allen and Peter Daniels (2012) Monitoring antigenic variation of H5N1 avian influenza viruses in Indonesia towards improved vaccine selection. Emerging Infectious Diseases Symposium, October 22-23, 2012, Geelong, Australia  Vosloo, W. (2012). Diagnostic tools and their role in the global control of Foot-and-Mouth Disease. Paper presented at the Second Global Conference on FMD control, Bangkok, Thailand.  Vosloo, W., Morris, J., Nguyen, T. T. H., Kim, P., Quach, N., Le, P., Singanallur, N. (2012). Using ropes to detect Foot-and-Mouth Disease virus infection in pigs. Paper presented at the Bi-Annual EUFMD Open Session, Jerez de la Frontera, Spain.  Wang, J. (2012). Molecular diagnosis of emergency animal diseases at the Australian Animal Health Laboratory. Paper presented at the Moleuclar Diagnostics Workshop 2012 - National Centre for Infectious Disease and Biosecurity (NCBID), New Zealand, Wellington, New Zealand.  Wong, F., Kim, M., Selleck, P., Stevens, V., Davies, K., Allen, J., Daniels, P. (2012). Update on H5N1 activity and diversification in Indonesian poultry. Paper presented at the 8th International Symposium on Avian Influenza, Royal Halloway, University of London, UK.  Wong, F., Selleck, P., Bruce, K., Allen, J., Claes, F., Kim, M., & Daniels, P. (2012). International avian influenza activities at AAHL: contributions to one health from regional veterinary surveillance programs. Paper presented at the Asia-Pacific Congress for Medical Virology, Adelaide.

______

Annual reports of OIE Reference Centres, 2012 9