TIBCO Spotfire DecisionSite System Requirements - v9.1.2

TIBCO Spotfire DecisionSite Client 9.1.2 Category Requirement Operating 2000 Professional SP4 System Microsoft Windows XP Professional and Home Edition SP2 or higher Microsoft Windows XP 64-bit Edition SP2 or higher Microsoft Windows Vista (32- and 64-bit) Business, Enterprise and Ultimate Editions Microsoft Windows 7 (32- and 64-bit) Business, Enterprise and Ultimate Editions Processor 500 Mhz or better RAM 128 MB (recommend 256 MB or greater) Hard disk space The installation footprint is approximately 30 MB Display VGA, resolution 800x600 pixels, 256 colors (Recommend 1024x768 pixels, 16 bit high colors or greater) Other Hardware Network card or high-speed modem with Web connection to download software CD-ROM (if installed from CD distribution) Mouse TIBCO Spotfire Connection to a TIBCO Spotfire Analytics Server 9 or 10 Software NOTE: TIBCO Spotfire Server 3.0 is not supported. Installation TIBCO Spotfire DecisionSite Client must be installed under a Privileges Windows user account with full administrative privileges. Anti-Virus TIBCO Spotfire DecisionSite Client should be installed with Software Anti-Virus software disabled.

In addition, Anti-Virus software should also be disabled when downloading Server-delivered DecisionSite applications (e.g. Statistics, Lead Discovery or Functional Genomics). Microsoft TIBCO Spotfire DecisionSite Client supports Internet Internet Explorer Explorer versions 6 SP2 through 8.

NOTE: It's not technically possible to install TIBCO Spotfire DecisionSite Client on a machine with (the unsupported) Internet Explorer 9 installed. Microsoft .NET TIBCO Spotfire DecisionSite Client requires Microsoft .NET Framework Framework 1.1 SP1 - 3.5 SP1 to operate. Microsoft .NET Framework 2.0 or later is strongly recommended.

Click here to download Microsoft .NET Framework 3.5 Service Pack 1 Microsoft TIBCO Spotfire DecisionSite Client supports Windows Script Windows Script versions 5.1 through 5.8. This software includes Visual Basic Script Edition (VBScript.), JScript (JavaScript), Windows Script Components, Windows Script Host, and Windows Script Runtime.

Microsoft Windows Script 5.6.0.8820 or higher is strongly recommended. This is the version supplied with Microsoft Windows XP SP2.

Click here to download Microsoft Windows Script. Microsoft Data TIBCO Spotfire DecisionSite Client supports versions 2.6 Access through 2.8 SP1 (2.81.1117.6). Components Click here to download Microsoft Data Access Components. Importing SAS It is possible to import SAS data files (*.sas7bdat, *.sd2, data files *.sd7) into DecisionSite Client directly. The requirement for this functionality is that the SAS Providers for OLE DB (version 9.1.3 - 9.22) must first be installed on the client machine.

Click here to download SAS Providers for OLE DB (free registration on SAS website required).

NOTE: Microsoft Windows Vista is not a supported platform for SAS Providers for OLE DB 9.1.3. Network TIBCO Spotfire DecisionSite Client requires a network Connection connection to a TIBCO Spotfire Analytics Server 9.0 or higher, either at the hosted TIBCO Spotfire Analytics Server or a customer-specific TIBCO Spotfire Analytics Server. Microsoft Microsoft Internet Explorer on the client should be configured Internet Explorer to access the TIBCO Spotfire Analytics Server via the Options Settings standard network connection. Downloading signed ActiveX components, scripts and cookies from the TIBCO Spotfire server must be allowed to pass through the firewall and proxy server, if restricted.

Internet Options for Microsoft Internet Explorer 6 General tab: - Temporary Internet Files - Settings - Check for newer version of stored pages: - "Automatically" Security tab: - Internet zone - Security Level - "Medium" or lower (set this first) - Security Level - Custom Level ActiveX controls and plug-ins - Download of Signed ActiveX controls - "Enable" - Run ActiveX controls and plug-ins - "Enable" - Script ActiveX controls marked safe for scripting "Enable" Downloads - File Download - "Enable" - Font Download - "Enable" Scripting - Active scripting - "Enable" - Allow paste operations via script - "Enable" - Scripting of Java applets - "Enable" Miscellaneous - Access data across domains - "Enable" - UserData Persistance - "Enable" User Authentication - Logon - "Automatic logon only in Intranet zone" or "Prompt for user name and password"

Note: If Windows Integrated Authentication/NTLM is enabled, "Automatic logon with current username and password" will also work.

Do not use "Anonymous logon", because that means that it is impossible to login to a server with a correct user name and password. - Trusted Sites zone - Sites - add TIBCO Spotfire Analytics Server URL (example: http://home.spotfire.net) - Security Level - "Medium" or lower (set this first) - Security Level - Custom Level - set to same settings as Internetzone Custom Level settings above Privacy tab: - Settings - Medium level - Advanced - First Party Cookies - "Accept" - Web Sites - Edit (to override cookie handling if necessary) - add TIBCO Spotfire Analytics Server URL (example: http://home.spotfire.net) Microsoft Office Office 2000 Service Pack 3 Office XP Service Pack 3 Office 2003 Service Pack 1 Office 2007 System Checker Use TIBCO Spotfire's System Checker tool to test client system compliance. Click here to download. Citrix See the following section for more information on deploying TIBCO Spotfire DecisionSite through Citrix.

Deploying TIBCO Spotfire DecisionSite Client 9.1.2 on Citrix Presentation Servers Category Requirement Citrix Software Deployment of the TIBCO Spotfire DecisionSite Client is supported on:

Client: Citrix Presentation Server Client Packager - Version 9.150 or 9.200 Server: Citrix Presentation Server version 4.0 TIBCO Spotfire In order to install TIBCO Spotfire DecisionSite Client on Citrix DecisionSite Servers, all the standard TIBCO Spotfire DecisionSite Client Client system requirements must be met.

NOTE: Microsoft Windows 2003 SP2 is a supported platform for TIBCO Spotfire DecisionSite Client when running via Citrix

In addition, the Citrix Presentation Server system requirements must also be met - please see the following Citrix support article for more information regarding this.

For more complete details on installation, configuration and publishing the TIBCO Spotfire DecisionSite Client application, refer to the documentation Running TIBCO Spotfire DecisionSite Client on a Citrix Server. TIBCO Spotfire In order to run TIBCO Spotfire DecisionSite Applications (i.e. DecisionSite Functional Genomics, Lead Discovery, etc), all the standard Applications system requirements for each application must be met. TIBCO Spotfire Deployment of TIBCO Spotfire Analytics Server on Citrix Analytics Server Presentation Server is not a supported configuration.

TIBCO Spotfire DecisionSite Computation Services 9.1.2 Category Requirement Microsoft Internet Explorer 6 SP2 or higher is required for Computation Internet Services. Explorer Computation For connection to local PC SAS: Services Client software Connector - SAS/Base v9.1.3 for SAS AND - SAS Integration Technologies Client for Windows (Release 9.1 or 9.1.3)

For connection to SAS Server: Client software - SAS Integration Technologies Client for Windows (Release 9.1 or 9.1.3)

Server software - SAS/Base v9.1.2 or v9.1.3 AND - SAS Integration Technologies v9.1.2 or v9.1.3

NOTE: SAS is third-party software that must be installed by the customer. Computation S-PLUS Server Services - Version 7 Connector for Insightful S-PLUS SOAP Kit Click here for more information... S-PLUS NOTE: Insightful S-PLUS is third-party software that must be installed by the customer. Computation NOTE: The environment is not a commercially supported product Services and TIBCO Spotfire cannot guarantee its functionality or stability. Connector TIBCO Spotfire has been tested against the following R for R Server configuration.

R on Red hat Enterprise 5.4 (including standard Software Development packages) - Version 2.2.1 (http://www.cran.r-project.org/src/base/R-2/R-2.2.1.tar.gz)

NOTE: R on other operating systems and newer versions of R have not been tested and may lead to unknown issues.

RSOAP - Version 1.1.4 (http://sourceforge.net/projects/rsoap/)

Python - Version 2.4.4 (http://www.python.org/ftp/python/2.4.4/Python-2.4.4.tgz)

Python modules - rpy 0.99.2 (http://heanet.dl.sourceforge.net/sourceforge/rpy/rpy-0.99.2.tar.gz)

- pyXML 0.8.4 (http://heanet.dl.sourceforge.net/sourceforge/pyxml/PyXML- 0.8.4.tar.gz)

- SOAPpy 0.12.0 (http://surfnet.dl.sourceforge.net/sourceforge/pywebsvcs/SOAPpy- 0.12.0.tar.gz)

- fpconst 0.7.3 (http://ovh.dl.sourceforge.net/sourceforge/rsoap/fpconst- 0.7.3.tar.gz)

NOTE: R and its related components are third-party software that must be installed by the customer. Computation SciTegic Pipeline Pilot Server Services - Version 5.0.x, 5.1.x, and 6.0.x Connector for Pipeline TIBCO Spotfire Software Pilot - DecisionSite Client 9.1.1 or higher and TIBCO Spotfire Analytics (additional Server 9.0 or higher. license required) NOTE: SciTegic Pipeline Pilot Server is third-party software that must be installed by the customer.

TIBCO Spotfire DecisionSite Statistics 9.1.2 Category Requirement TIBCO Spotfire Connection to TIBCO Spotfire Analytics Server 9.0 or higher Software via TIBCO Spotfire DecisionSite Client 9.1.1 or higher.

TIBCO Spotfire Developer Network Category Requirement Web connection Web connection to access TIBCO Spotfire-hosted website at http://developer.spotfire.com Microsoft Microsoft Internet Explorer 6 SP2 or higher. Internet Explorer

TIBCO Spotfire DecisionSite Builder Category Requirement Operating Microsoft Windows 2000 Professional SP4 System Microsoft Windows XP Professional and Home Edition SP3 Installation TIBCO Spotfire DecisionSite Builder must be installed under Permissions a Windows user account with full "Administrator" permissions. Microsoft Microsoft Internet Explorer 6 SP2 or higher Internet Explorer Microsoft Windows Script 5.6 versions of build 5.6.0.8820 or higher Windows Script Microsoft XML Microsoft XML Core Services (MSXML) v2.6 or higher Core Services Microsoft Code In order to be able to sign code, the Microsoft code signing Signing tool tool (signcode.exe) is required. This utility is included in:

 Microsoft Authenticode for IE5  Microsoft Platform SDK, version 1.0 and 1.1 (NOTE: Later versions of this do not include the signcode.exe utility)  Microsoft .NET Framework SDK, version 1.0 and 1.1

TIBCO Spotfire TIBCO Spotfire Analytics Server 9.0 or higher Software TIBCO Spotfire DecisionSite Client 9.1.1 or higher

TIBCO Spotfire API Terminal Category Requirement TIBCO Spotfire Connection to TIBCO Spotfire Analytics Server 9.0 or higher Software via TIBCO Spotfire DecisionSite Client 9.1.1 or higher.

TIBCO Spotfire DecisionSite for Functional Genomics 9.1.2 Category Requirement TIBCO Connection to TIBCO Spotfire Analytics Server 9.0 or higher via Spotfire TIBCO Spotfire DecisionSite Client 9.1.1 or higher. Software Affymetrix Will access binary CHP files and metrics file output from GCOS Files 1.1 and 1.2. Affymetrix Will access Oracle, SQLServer and MicroDB databases Database containing data generated output from Affymetrix Microarray Suite 4.0 and 5.0. Affymetrix To utilize the new feature to automatically add NetAffx annotation NetAffx data to your existing dataset, you will need to:

1. Install the NetAffx SDK which can be downloaded here. 2. Have a valid NetAffx login and password to access the annotation data. If you do not have a NetAffx login, you can go to the Affymetrix website: http://www.affymetrix.com and click the Register link.

TIBCO Spotfire DecisionSite for Lead Discovery 9.1.2 Category Requirement TIBCO Spotfire Connection to TIBCO Spotfire Analytics Server 9.0 or higher Software via TIBCO Spotfire DecisionSite Client 9.1.1 or higher. Chemistry Included Data Sources: Services Components  SDFiles **  SMILES strings in DecisionSite dataset **  ChimeStrings in DecisionSite dataset ** One available  MOL files in DecisionSite dataset ** data source, renderer, and Available Data Sources - Local TIBCO Spotfire Analytics editor Server: component provided with  MDL ISIS/Host, version 5.1  MDL Direct (formerly ISIS/Direct and Relational Chemistry Server), Analytics Server versions 5.1 or 6.0 license.  MDL ISIS/Base, version 2.4 and later Additional  Accelrys Accord Chemistry Cartridge version 6 components may  CambridgeSoft Oracle Cartridge version 9.0  Daylight DayCart version 4.83 be purchased.  JChem Oracle Cartridge version 3.2.1  MOL files on client PC filesystem **  MOL files in Oracle CLOB or BLOB **  SMILES strings in JDBC-compliant database **

Available Data Sources - Hosted TIBCO Spotfire Analytics Server (home.spotfire.net):

 MDL ISIS/Host, version 5.1  MDL ISIS/Base, version 2.4 and later  MOL files on client PC filesystem **

** denotes data sources which do not support structure searches

Available Renderers:

 MDL Draw Enterprise Edition 2.1 or 3.0  MDL ISIS/Draw, version 2.4 and later  Accord Chemistry Control version 6  CambridgeSoft ChemDraw version 8, 9 or 10 (Pro or Ultra)  MarvinSketch version 4.1.3

Available Editors:

 MDL Draw Enterprise Edition 2.1 or 3.0  MDL ISIS/Draw, version 2.4 and later  CambridgeSoft ChemDraw version 8, 9, or 10 (Pro or Ultra)

SDFiles Standard SDFiles can be imported and exported directly into and out of DecisionSite. If there are MOL formatted structures in an imported SDFile, they will be automatically rendered by the 3rd party MOL rendering tool for which you have the appropriate Chemistry Services Component. MDL Notes NOTE: The system requirements for MDL Products can be found at www.mdl.com.

NOTE: TIBCO Spotfire supports MDL Molecules databases. TIBCO Spotfire does not support Reaction databases.

NOTE: Occasionally customers have difficulty connecting DecisionSite for Lead Discovery to complex Hviews. For example, Hviews containing multiple levels of nesting and concatenated databases may be difficult to align with the data model in DecisionSite. Such issues have typically been resolved by using Hviews with a simplified structure, e.g., Compound ID and structure only.

NOTE: The functionality of DecisionSite for Lead Discovery will to some extent depend on the MDL software configuration, as in the following examples:

 Similarity search is not available for local ISIS databases  Key-based clustering is supported for the 166 structure key set when stored in ISIS as comma separated numbers

TIBCO Spotfire DecisionSite MapConnect 9.1.2 Category Requirement TIBCO Spotfire Connection to TIBCO Spotfire Analytics Server 9.0 or higher Software via TIBCO Spotfire DecisionSite Client 9.1.1 or higher. ESRI Software Versions 9.0, 9.1 or 9.2 of one of the following: ESRI ArcView ESRI ArcEditor ESRI ArcInfo ESRI ArcGIS ESRI ArcMap