2012 Cincinnati Children's Annual Report

ILLUMINATING DISCOVERIES

Production credits TABLE OF CONTENTS Affiliates Performance Leadership Team

Adolescent Health Center Michael Fisher Marianne F. James Produced by the Department of 2 Message from our CEO and Chairman of Greater Cincinnati President and Chief Executive Officer Senior Vice President, Information Marketing and Communications 4 Message from our Finance Leaders Janet Ach Services, and Chief Information Officer Cincinnati Children’s Hospital Medical Center Richard G. Azizkhan, MD President Jane Garvey, Vice President 6 Casting Light on a Rare Lung Disease Surgeon-in-Chief William M. Kent Frank Biro, MD Senior Vice President, Infrastructure Writer/project director 14 Tribute: William Kuenneth Schubert, MD Elisabeth Baldock, PhD Director, Division of Adolescent Medicine and Operations Beatrice Katz Senior Vice President, Human Resources CINCINNATI CHILDREN’S HOSPITAL MEDICAL CENTER 16 Deciphering the Mysteries of Eosinophilic Disorders Children’s Dental Uma R. Kotagal, MD Design Mitchell Cohen, MD 22 Revealing the Power of a Life-Altering Drug Care Foundation Senior Vice President, Quality Real Art Vice Chair of Pediatrics for Clinical Affairs Michael Lee, DDS and Transformation 28 Guiding Asthma Patients to a Better Quality of Life Donor recognition President Brian D. Coley, MD Charles Dean Kurth, MD Elli Edwards, Jennifer Sennett, 32 The Convalescent Hospital for Children: Radiologist-in-Chief and Director, Stephen Wilson, DMD, MA, PhD Anesthesiologist-in-Chief and Director, Shannon Studebaker Evolving, Educating, Empowering Department of Radiology Director, Division of Pediatric Dentistry Department of Anesthesia Photography 34 Donor Recognition Dwight E. Ellingwood Convalescent Hospital Frederick Ryckman, MD Ryan Kurtz; additional photos from Senior Vice President, Planning 77 Financial Report for Children Senior Vice President, Medical Operations the Cincinnati Children’s archive and Business Development Pamela Terp 80 Our Leaders James A. Saporito Printing Chair Michael K. Farrell, MD Senior Vice President, Development Wendling Printing Company Chief-of-Staff Phillip C. Long Elizabeth A. Stautberg, Esq. President Jane Garvey General Counsel and Senior Vice Vice President, Marketing Cincinnati Children’s Hospital Medical Center is a teaching Jack Rubinstein Foundation President, Legal and Public Affairs affiliate of the University of Cincinnati College of Medicine. and Communications for Developmental Disorders The medical center is accredited by The Joint Commission; Arnold W. Strauss, MD CARF, The Rehabilitation Commission; and the Association JoAnn Hagopian Tracy Glauser, MD Physician-in-Chief; Chair, Department for the Accreditation of Human Research Protection Programs, Inc. President Associate Director, Clinical Translational of Pediatrics, University of Cincinnati; We have been awarded Magnet recognition from the American Outcomes and Health Services Research, Nurses Credentialing Center for quality patient care and nursing David Schonfeld, MD and Director, Cincinnati Children’s Cincinnati Children’s Research Foundation excellence. Our pediatric residency training program is approved COVER Director, Division of Developmental Research Foundation ILLUMINATING by the Accreditation Council for Graduate Medical Education. Jordan Scott, 9, has eosinophilic

and Behavioral Pediatrics Scott J. Hamlin 2012 ANNUAL REPORT Cincinnati Children’s affirmatively seeks to attract to its staff esophagitis and is a patient of the Cincinnati Jeffrey Whitsett, MD Executive Vice President appropriately qualified persons of diverse backgrounds. The medical Center for Eosinophilic Disorders. Interim Associate Director, Basic Sciences, and Chief Operating Officer DISCOVERIES center does not discriminate against any employee or applicant Cincinnati Children’s Research Foundation based on race, color, creed, religion, sex, sexual orientation, BRIDGING RESEARCH, CARE AND COMMUNITY Cheryl Hoying, PhD, RN ancestry, national origin, age, disability, political affiliation or status as a disabled veteran or veteran of the Vietnam conflict. Senior Vice President, Department of Patient Services Cincinnati Children’s ranked third among all pediatric hospitals in the 3333 BURNET AVENUE, CINCINNATI, OHIO 45229-3026 2012 U.S. News & World Report survey of best children’s hospitals.

2012 ANNUAL REPORT From left to right: Cincinnati Children’s first home was a rented house. Two William Cooper Procter gave $2.5 million to build and endow the Children’s Hospital Research Foundation. Three Cincinnati Children’s was the first pediatric hospital to have a building dedicated to research. From left to right: Albert Sabin, MD, spent 30 years at Cincinnati Children’s. The Sabin oral polio vaccine was adopted by the World Health Organization in its campaign to eradicate polio worldwide. Two In 1988, Jeffrey Whitsett, MD, announced his research team had identified and cloned two It opened in 1931. Four Josef Warkany, MD, arrived January 1, 1932, for a one-year fellowship. He spent his entire career at Cincinnati Children’s, becoming a pioneer in the study of birth defects. Five Chemist and inventor Leland Clark, PhD, developed the first functional heart-lung machine. proteins essential for human surfactant. Today surfactant replacement therapy is routinely used to save the lives of premature infants with respiratory distress syndrome. Three Richard Ward, PhD, began studying rotavirus in 1981. His research, in partnership with David Bernstein, MD, led to development Using Clark’s machine, the cardiology team at Cincinnati Children’s performed the first open heart surgery. of a safe, effective vaccine to prevent rotavirus infection. The vaccine is now used around the world. Four Cincinnati Children’s broke ground for a new clinical sciences building in 2012. The 425,000 square foot building will provide space to consolidate and expand patient-oriented research activities.

1976 2007 1931 1957 2003 2010 1926 1963 Lonnie Wright, MPH, PhD, Location S opens on 1883 1924 The Children’s Hospital Research 1939 1951 The World Health 1988 1993 Demolition of the 1926 hospital Michael Fisher succeeds The Children’s Hospital establishes an academic Edward Pratt, MD, is named is appointed the hospital’s first the site of the 1926 Incorporation papers for Procter forms a dynamic Foundation opens. The Children’s Albert Sabin, MD, joins The Children’s Hospital Research Chemist Leland Clark, PhD, then based Organization chooses Neonatologist Jeffrey Whitsett, MD, Thomas Boat, MD, succeeds Dr. Schubert begins to make way for a new James Anderson as affiliation with the College of Medicine as chairman of Pediatrics and full-time president and CEO. hospital. The building the Protestant Episcopal partnership with Hospital is the nation’s first pediatric Foundation. His research proved that poliovirus enters at Antioch College, brings his bubble Sabin’s vaccine for announces his team has identified as chairman of Pediatrics and director of the research building. Construction president and CEO. the Department of Pediatrics. Dr. Mitchell director of The Children’s adds 415,000 square Hospital for children are the newly appointed hospital with a building dedicated the body through the digestive tract. He also found polio- defoam oxygenator heart-lung bypass machine worldwide testing. Millions and cloned two proteins essential Children’s Hospital Research Foundation. begins in 2004. is the first to be both chair of Pediatrics and Hospital Research Foundation. feet for research. Reflecting signed November 16, 1883. to research. resistant antibodies in some children, suggesting they 1979 to human surfactant. The discovery 2012 B.K. Rachford Chair physician-in-chief of The Children’s Hospital, to Cincinnati Children’s. Cardiologist Samuel of doses are given in Russia, the depth and breadth The hospital opens in had been infected by a weakened strain that produced made it possible to produce synthetic 1996 2004 of Pediatrics of the a tradition that continues today. Kaplan, MD, and surgeon James Helmsworth, Holland, Mexico, Chile, The Clinical Research Center Dr. Schubert succeeds of its research program, Cincinnati Children’s a rented three-bedroom 1921 1932 immunity. Based on these observations, he developed human surfactant for treating James M. Anderson succeeds Dr. University of Cincinnati MD, work with Clark to perfect it. A prolific Sweden and Japan. is established, with William Dr. Pratt as chairman The rotavirus vaccine Cincinnati Children’s breaks ground for a house in March 1884. On December 6, the hospital moves into its the world’s first attenuated (weakened) live-virus premature infants with respiratory Schubert as president and CEO. William Cooper College of Medicine, Albert Josef Warkany, MD, arrives from inventor, Dr. Clark also developed the Clark K. Schubert, MD, as its of the Department developed by Richard Ward, is now second in the 425,000 square foot new, 200-bed facility adjacent to the college, vaccine–the Sabin oral polio vaccine. 1960 distress syndrome. Procter, president of Graeme Mitchell, MD. Vienna for a one-year research oxygen electrode, which is used worldwide founding director. of Pediatrics and director PhD, and David Bernstein, nation in NIH grants clinical sciences building 1887 built on land Procter selected and purchased. Procter & Gamble, is Working together over the fellowship. He spends his entire in medical and industrial applications. The first US test of of the Children’s Hospital 1998 MD, is licensed in Mexico. for pediatric research. that will provide space Hospital moves elected president of next decade, Procter and and highly productive career 1942 the Sabin oral polio 1968 Research Foundation. 1991 Cincinnati Children’s begins Today the vaccine is used in to consolidate and expand to its second home. the hospital’s board of Dr. Mitchell increase the 1928 at Cincinnati Children’s. Ashley Weech, MD, is named chairman 1952 vaccine begins in The Institute for First new research building an ambitious building expansion. over 100 countries, and the Arnold Strauss, MD, patient-oriented research. The new hospital trustees, a position he size of The Children’s Dr. Mitchell advocates for research at Known as the father of teratology, of Pediatrics and director of The Children’s Using the heart-lung machine, the Cincinnati on April Developmental Research 1983 since 1968 opens, providing Over the next four years, the Sabin World Health Organization succeeds Dr. Boat When the building opens opens with 20 held until his death in Hospital, enlarge the staff The Children’s Hospital. In December, Dr. Warkany did pioneering Hospital Research Foundation. After WWII Cincinnati Children’s team performs 24, 1960, known as (IDR) opens. The building Dr. Schubert space for 19 research programs Education Center, a research wing, has recommended that as chair of Pediatrics in 2015, Cincinnati beds on two wards 1934. The hospital’s and expand the hospital’s Procter announces a gift of $2.5 million research on nutritional and ends, he expands the faculty, adding directors the earliest open heart surgery, reported Sabin Sunday. More doubled office and laboratory is appointed in 240 new labs. Research a garage, and a new hospital rotavirus vaccine be and director of the Children’s will have and room for two name is changed to mission to include medical to build and endow The Children’s environmental factors that of new subspecialty divisions as the field of in the Journal of the American Medical than 20,000 children space, and allowed a large president is increasingly focused building (now called Location A) included in all national Cincinnati Children’s 1.4 million square feet additional wards. The Children’s Hospital. education and research. Hospital Research Foundation. cause birth defects. pediatrics becomes increasingly specialized. Association (October 4, 1952). received the vaccine. influx of research scientists. and CEO. on molecular genetics. are added to the Burnet Campus. immunization programs. Research Foundation. for research.

Building a Research Legacy 1956–2012 on back cover 1883–1955 on FRONT cover Improving Child Health ILLUMINATING DISCOVERIES

Production credits TABLE OF CONTENTS Affiliates Performance Leadership Team

2012 ANNUAL REPORT ILLUMINATING DISCOVERIES BRIDGING RESEARCH, CARE AND COMMUNITY

2012 ANNUAL REPORT Dear Friends,

In our annual reports, we try to capture in words and These inspiring achievements are changing the outcome We remember 2012 as a year of exciting beginnings but pictures the vision that drives Cincinnati Children’s and for our patients today–and illuminating the way to also sad losses. In February, we lost one of our greatest our many partners: the passion to improve child health; a healthier future for children everywhere. leaders–William Kuenneth Schubert. the commitment to discovery, innovation and improvement. As leaders of Cincinnati Children’s, we know that a great In a career spanning nearly 50 years at Cincinnati Children’s, This year, we focus on one of the most powerful ways we and enduring institution must excel in the present and Dr. Schubert was a distinguished pediatrician, teacher, child improve child health: through patient-oriented research. continually look to the future. The strength of Cincinnati advocate, researcher and leader, as well as a generous supporter. Children’s today is a tribute to the wisdom, vision Research at Cincinnati Children’s spans the entire arc He made immeasurable contributions to our institution, and actions of leaders, staff and supporters throughout from basic science through application and outcomes our community and to the families we are privileged to our 129-year history. It’s the responsibility of this research, from bench to bedside and into the community. serve. We continue to build on the legacy he left. generation to plan for the well-being of the children Every day, we strive to cast new light on complex diseases– and families who will need us 129 years from now. and most importantly, to translate discoveries into new treatments that make a difference for patients. We were proud, therefore, to announce plans in April 2012 Sincerely, to build a new clinical sciences building. When it opens In this report, you’ll read about three programs that in 2015, it will provide space to consolidate and expand excel in bridging research, discovery and care. patient-oriented research activities. It will allow us to You’ll learn about two girls from Kuwait who are in strengthen the critical link between research and patient Cincinnati for lifesaving care of a rare lung disease, outcomes. It will help us do more, learn more and improve Michael Fisher and about pioneering research that offers them hope the lives of more children and families. President and CEO of a cure. You’ll learn how researchers and parents formed This investment is a mark of our unwavering commitment a productive partnership that resulted in rapid advances to improve child health. We move forward knowing that in the fight against eosinophilic gastrointestinal disorders. achieving the best results for children will take support And you’ll learn about leading-edge clinical trials of the from many partners and donors who share the passion Thomas G. Cody first medicine that can shrink brain, kidney and lung to make a difference. Together, we will advance knowledge, Chairman tumors in patients with tuberous sclerosis. improve care and change lives.

TOP TO BOTTOM Michael Fisher, Thomas Cody 3 Dear Friends,

In many ways, fiscal 2012 represents the culmination of This approach demands that we work with community In the end, revenue growth stimulated by increased demand a long, steady financial journey and first steps toward partners and stakeholders in ways we are only beginning for services, coupled with successful per-patient-treated a new way forward. to harness and adequately support. cost reductions led to net operating revenues of over $128 million–a strong improvement over last year. This, in turn, For the past seven years, Cincinnati Children’s has been Conversely, our commitment to being the global leader will allow us to accelerate our investment in new scientific exceptionally focused on improving and expanding for complex pediatric care requires a business model based discovery, new program offerings, expanded community programs, facilities, partnerships and infrastructure to on unique clinical capabilities coupled with leading-edge partnerships and in the infrastructure and family support meet two complementary but different goals: to better scientific discovery. To succeed, we must differentiate our our patients require. serve our community’s children and to be the global services from the national and global market and establish leader in providing complex care for patients from Cincinnati Children’s as the destination of choice for all geographies. The responsibilities and stewardship highly specialized care. associated with these roles required financial excellence Sincerely, The improved financial results of fiscal 2012 (see Financial in two very different and demanding business models. Report, pages 77-79) hint at the powerful potential locked As the community’s leader in promoting and improving within our journey to become far better at both roles– the health of our region’s children and teens, Cincinnati community leader and global leader. The statistical Children’s recognizes that healthcare must shift from a highlights in our financial report show that we were able Scott Hamlin system focused on delivering medical services to a new to touch the lives of a record number of patients and Executive Vice President and COO model that empowers children and families to take families in virtually every setting in which we provide charge of their own health. This year’s annual report care. Increased demand for our services and expertise features a story about our efforts to help families whose led to operating revenues that grew nearly 9 percent to children have asthma manage the disease more effectively $1.85 billion this year. And equally satisfying, our per Robert D.H. Anning and reduce their need for hospital care. This shift in patient encounter cost of providing clinical care actually Chair, Finance Committee philosophy requires a new business model–one focused decreased about 4 percent on an inflation-adjusted basis, on strengthening the patient’s self-management skills as a result of an institution-wide effort to decrease costs and on ensuring that when care is required, families have and improve efficiency and productivity. A nation hungry access to the right care, at the right time, in the right for demonstrably better value from its healthcare system Felicia Williams setting, which may well be outside our hospital walls. is demanding that we take this success much further in Chair, Audit and Compliance Committee the coming years–and we are committed to doing that.

TOP TO BOTTOM Scott Hamlin, Robert D. H. Anning, Felicia Williams 5 Nawaf and Fatemah Al-Shammari searched the world for a doctor who could help their daughter. By the time the search led them to Cincinnati Children’s, hope was running out for 3-year-old Nourah.

She was desperately ill from a mysterious lung disease. Within a month Nourah was in the ICU, unconscious, on a respirator. While she was in the ICU, her doctors At Cincinnati Children’s, the Al-Shammari family found performed the bronchoscopy. The results were surprising: a doctor with expertise in the complex treatment Nourah They didn’t find infection or inflammation, but sediments– needs. And more, they found a research team with expertise evidence of a very rare lung disease. Nourah Al-Shammari came to Cincinnati Children’s for in lung biology. lifesaving treatment for a rare lung disease. Now a cure Her parents and medical team began searching for help It’s a rare combination: outstanding patient care side- is on the horizon, thanks to pioneering research. outside Kuwait. by-side with outstanding research; collaboration among the doctors who treat sick children and the researchers “I sent her records to many hospitals,” her father recalls, studying what underlies disease; basic science grounded “but no one would accept her case.” in clinical challenges. Nourah’s doctor sought advice from pulmonary experts C asting For Nourah, it’s a combination that made all the difference. worldwide through an online discussion group on the internet. That’s how he found Robert Wood, MD, PhD, The best available treatment saved her life. Innovative director of bronchoscopy at Cincinnati Children’s. research offers hope for a complete cure. Light “I saw his inquiry and recommended whole lung lavage,” says A Mysterious Lung Disease on a Rare Lung Disease Dr. Wood. “He asked if he could send his patient to me.” Born in Kuwait in 2005, Nourah was an apparently healthy baby until she was 2½ years old. Then suddenly she became “ Wood’s Lung Laundry” very sick with asthma and coughing. She grew lethargic. Whole lung lavage (WLL) is a complicated procedure, used She turned blue. to treat pulmonary alveolar proteinosis (PAP). For decades the only thing known about this rare disease was that What was making her so sick? patients with PAP have too much surfactant in their lungs, A lung specialist wanted to do a bronchoscopy exam, making it difficult for them to get air in. but Nourah was too sick to risk giving her anesthesia Surfactant, a fatty substance produced by the lungs, reduces for the procedure. surface tension and keeps the lung’s tiny air sacs (alveoli)

7 excess surfactant. As a result, her family has remained in laboratory studies of an innovative genetic therapy that, Cincinnati since 2008. Dr. Wood washes her lungs every in preliminary tests, cures it. 3 to 6 weeks. Nourah and Bashayer will be in the first group of patients Cousin Bashayer Arrives offered the new therapy when it is approved for testing Nourah is alive today because of the expert care available at in humans. Cincinnati Children’s. But the story is far more complicated. Decades of Discovery Back home in Kuwait, her cousin, Bashayer, also suffered Scientists at Cincinnati Children’s have been at the leading from pulmonary alveolar proteinosis. Not long after Nourah edge of research on surfactant-related diseases since the arrived in Cincinnati, Bashayer’s family moved here, too. 1980s, when a team led by neonatologist Jeffrey Whitsett, MD, did groundbreaking work on respiratory distress Dr. Wood now was treating first cousins–just 3 and 4 Whole Lung Lavage Nourah undergoes whole lung lavage every three to six weeks. In the OR, Dr. Robert Wood inserts syndrome in premature infants. a breathing tube into her lungs. He keeps one lung mechanically ventilated and dry while he fills the other with saline, vibrates her years old–with PAP. chest wall to mix the surfactant into the saline, and then drains her lung. He repeats this several times. The process is repeated at a later The lungs of premature babies are not able to produce Very unusual. time to clean the other lung. enough surfactant. Respiratory distress due to insufficient For decades, PAP was believed to be an acquired disease, surfactant is a killer in these tiny babies. occasionally seen in children, but mostly in adults. Dr. Whitsett made an important breakthrough in the Today, because of Nourah, Bashayer and a handful of fight to save preemies. He identified and cloned two open. Having either too little or too much surfactant Dr. Wood, one of the world’s experts, has 40 years of other young patients, researchers at Cincinnati Children’s proteins essential to human surfactant. His research made is life-threatening. experience with the procedure in children. He agreed have identified a previously unknown hereditary type it possible to produce a genetically engineered surfactant to see Nourah. of PAP (hPAP). treatment for preemies. Surfactant replacement therapy Without it, air sacs in the lung collapse when we exhale is now routinely used in newborn ICUs–saving thousands and struggle to expand with a new breath. This is what The US and Kuwaiti embassies worked together to get Working rapidly, a research team led by Bruce Trapnell, MD, of babies every year. happens in premature babies who are born before their the family the necessary travel visas and arrange the 6,800 developed a test to diagnose hPAP and is conducting lungs have developed the capacity to produce surfactant. mile trip, accompanied by a doctor and nurse.

But if we have too much surfactant, as in PAP, it fills Dr. Wood performed Nourah’s first lavage treatment just

up space that should be filled with air. three days after she arrived in Cincinnati in November Opportunities for Discovery 2008. He washed her lungs with many liters of saline to There’s only one treatment for PAP: washing the lungs remove the surfactant sediment. Within three weeks, she “ You have to know enough basic science to be able to problem solve, and you have to understand the to get rid of excess surfactant. “Lung laundering,” was well enough to leave the hospital. disease enough to know what you’re looking for. Cincinnati Children’s brings the two halves together– as Dr. Wood calls it. Though the treatment is effective, lavage is a temporary research and clinical care, tools and patients. The combination makes this one of the best places on the Not many hospitals have the ability to perform whole lung fix. Nourah’s lungs continue to become clogged with lavage on a child as young, tiny and fragile as Nourah. planet to do pulmonary research.” Bruce Trapnell, MD

8 9 Dr. Whitsett and his research team have continued to focus “When this work began, no one knew how PAP intensively on lung biology and surfactant-related diseases. developed,” says Dr. Trapnell. “In fact, there was In fact, their research in the 1990s helped explain the basic a lot of misunderstanding.” People thought PAP was biology of PAP. the result of the body producing too much surfactant. Piece by piece, a different picture emerged from The Basics of PAP laboratory research at Cincinnati Children’s. The work began when scientists at MIT turned to Dr. Whitsett for help. They were trying to understand It turns out that PAP is not due to overproduction the role of a newly identified protein, GM-CSF (granulocyte of surfactant but under-clearance of old, used surfactant. macrophage colony-stimulating factor). The protein appeared Research showed that GM-CSF is needed for macrophages to promote the growth of macrophages. It was important to mature. If the cells don’t mature, they can’t do their job. to understand GM-CSF’s role, because macrophages in In the lung, a key job is to get rid of used surfactant. If they Left Jeffrey Whitsett, MD, conducted research in the 1980s that resulted in lifesaving surfactant replacement therapy for premature our white blood cells are a key part of the immune system. don’t do this, the surfactant accumulates as sediment. babies with respiratory distress syndrome. Right Cincinnati Children’s investigators have continued to focus on surfactant-related diseases. The research team studying hPAP includes (l-r) Takuji Suzuki, MD, PhD, Brenna Carey, PhD, and Bruce Trapnell, MD. Described as garbage collectors, macrophages travel through Over time, the lungs fill up. the body, looking for trash, such as worn out cells or toxins As this insight became clear, a research team in Japan or bacteria. When they find something that shouldn’t discovered that patients with PAP had an antibody against be there, they surround it and digest it. GM-CSF. By the early 2000s, the Japan and Cincinnati After a decade of work, we thought we had a pretty clear They reanalyzed the data and retrospectively found five To learn more about the role of GM-CSF in this process, teams were working together. picture of the basic biology of PAP. Until we started other cases. Then Nourah and Bashayer arrived. the scientists created a model in mice by knocking out the Meticulous work at Cincinnati Children’s proved that the seeing patients like Nourah and Bashayer. gene that makes the GM-CSF protein. They expected to By now there were enough cases to begin to define the antibody was not merely present, but was actually causing find that the mice would not be able to make macrophages. Because it turned out, they don’t have the antibody. natural history of this new condition. Going further, the disease. Dr. Trapnell developed a test to diagnose it, and he That’s not what happened. The mice did produce Hereditary PAP This finding defined PAP as an autoimmune disorder– created a mouse model to study it in the lab. macrophages, but oddly enough, the mice had a lot In 2007, Dr. Wood saw a 6-year-old girl from North Carolina a condition in which the body mistakenly attacks its own of surfactant in their lungs. Why? who appeared to have PAP. But when Dr. Trapnell ran the Molecular analysis identified a genetic defect in the normal functioning. diagnostic test on a blood sample, she did not have the antibody. macrophages. They can’t receive signals from GM-CSF. The researchers needed an expert in lung disease and One output of the research was a diagnostic test for When he measured her GM-CSF level, it was elevated. Since they don’t get the right message, they don’t clean surfactant. They turned to Dr. Whitsett, who recognized autoimmune PAP, making a bridge from the basic science up old surfactant. the mice had PAP. This was something new. lab to clinically relevant information. Today Cincinnati The outcome is the same as in autoimmune PAP–too Researchers at Cincinnati Children’s have been studying Children’s is one of just four centers worldwide that Over the years the research team had carefully maintained much surfactant in the lungs. But the disease pathway PAP ever since. performs diagnostic testing for autoimmune PAP. a database of patient information and blood samples. in hPAP is quite different.

10 11 Parents, physicians and researchers all feel a sense of urgency, “We know exactly where the target is,” says Dr. Trapnell. yet know the work must move forward step by step. It may “By deepening our understanding of the basic biology, we take two years or more before all the preclinical work can move toward therapy for these conditions, and we are is completed and Cincinnati Children’s receives approval likely to learn something more general about autoimmune to begin human testing through a clinical trial. and genetic diseases that can be applied to other, more common and complex conditions.” In the meantime, Nourah and Bashayer need regular lavage treatments. Is there a way they can have these treatments The long-term investment in lung research at Cincinnati in Kuwait? Children’s has had an enormous impact. It bridged the gap between understanding basic biology and advancing Dr. Wood has begun training Kuwaiti physicians to perform care to improve the health of children. whole lung lavage in children as small as Nourah and Left Bashayer Al-Shammari, Nourah’s cousin, also has hPAP and undergoes regular whole lung lavage treatments at Cincinnati Bashayer. As a first step, a Kuwaiti team visited Cincinnati Basic science studies of surfactant led to a lifesaving Children’s. Right Nawaf Al-Shammari searched the world for a hospital that could help his daughter. Here he shares a quiet Children’s in April to observe the procedure. A second trip treatment for respiratory distress syndrome in premature moment with Nourah. for more training and hands-on experience is being planned, infants and to an ongoing interest in other surfactant- in preparation for the children to return to Kuwait. related diseases, including PAP.

“They deserve to be home,” Dr. Wood says. Studying hPAP led to inventing a new procedure– pulmonary macrophage transplantation. “It’s not just Next Steps “We have all the facilities here,” says Dr. Trapnell. “We’ll do Why Study Rare Disease? a new treatment,” Dr. Trapnell says, “but a new class In a stunning advance, the basic research quickly led to a new the preclinical studies on safety and dosing. The Cincinnati PAP is a very rare disease–fortunately. One of the reasons of treatment.” It opens the potential for new therapeutic type of therapy: pulmonary macrophage transplantation. Children’s Vector Lab will make the gene therapy vector to focus on rare diseases, Dr. Trapnell points out, is that approaches to other lung diseases. and the Cell Manipulation Lab will prepare the cells for they typically have a single cause that can be isolated In the lab, Dr. Trapnell’s team is able to correct the gene defect genetic therapy. We have all the necessary infrastructure.” and studied. The possibilities are speculative at this stage. But that’s in mice macrophage cells and put the cells back into the lung. a critical part of clinical science: linking clinical need, For Nourah and Bashayer, macrophage transplant offers Autoimmune PAP is caused by an antibody that attacks “Because the GM-CSF levels are high, the macrophages creative thinking and meticulous basic science to push the hope of a complete cure. only one protein in a single signaling pathway that we put into the lung proliferate,” he explains. “They go the boundaries of knowledge, advance care and improve macrophages require to function normally. Hereditary through the lung like Pac-Man, cleaning up surfactant. “We’re very happy that there’s a treatment,” says Fatemah outcomes for patients. PAP is caused by a defect in another single component As they do this, they also get rid of excess GM-CSF, so Al-Shammari. “The girls can’t have lung lavage all their lives.” of the same signaling pathway. Cincinnati Children’s is proud to be at the forefront the whole system comes back into equilibrium. It works “Despite more than 20 years of research, not one lung of such cutting-edge translational research. so well, with just one treatment.” disease has been successfully treated by gene therapy,” Cincinnati Children’s is uniquely positioned to move Dr. Trapnell points out. “This has the potential to be this research from the lab to patients. a major advance, the first successful lung gene therapy.”

12 13 William Kuenneth Schubert, MD July 12, 1926–February 25, 2012

The Cincinnati Children’s community mourns the director of the Clinical Research Center. In 1968, he As a child advocate, he was a spokesman for the position Awards HONORING Dr. Schubert passing of one of our greatest leaders, William Kuenneth established the Division of Gastroenterology. He also that no child should be turned away for lack of ability Schubert, MD. served as director of the pediatric residency program to pay. He worked tirelessly to pass the Hamilton County 1989 William Cooper 2003 Murray Davidson and chief-of-staff. He went on to be chairman of the Health and Hospitalization tax levy and to consolidate Procter Medallion Award (American Academy In a career spanning nearly 50 years at Cincinnati Children’s, Department of Pediatrics and director of the Cincinnati pediatric care at Cincinnati Children’s, so that all kids (Cincinnati Children’s) of Pediatrics, Section Dr. Schubert dedicated his life to improving the health Children’s Research Foundation (1979-93) and president could be treated equally. on Gastroenterology) of children in our community and around the world. 1991 Daniel Drake Medal and CEO (1983-96). (University of Cincinnati 2004 Great Living He made immeasurable contributions as a physician, Under his leadership as chairman of Pediatrics and College of Medicine) Cincinnatian (Cincinnati child advocate, researcher, teacher, mentor and leader. Dr. Schubert was a compassionate physician, a brilliant president and CEO, Cincinnati Children’s grew in USA Regional Chamber) And throughout his career, he gave generously to support diagnostician and an outstanding educator. He inspired clinical and research programs, recruited world-class 1992 Distinguished the work of the institution he loved. generations of pediatricians and pediatric specialists. talent and added new facilities. After he retired in 1996, Alumni Award (University 2011 Business Hall Dr. Schubert continued to serve Cincinnati Children’s of Cincinnati College of of Fame (Jr. Achievement A Cincinnati native, Dr. Schubert attended the University As a scientist, he did important research on liver disease, as a trustee, advisor and elder statesman. Medicine) of Greater Cincinnati) of Cincinnati College of Medicine and completed his cholesterol, iron deficiency and Reye syndrome. He was 2003 Lifetime Hero pediatric residency and fellowship training at Cincinnati a model of the clinician/researcher and encouraged Award (Cincinnati Children’s. After seven years in private practice, he joined physicians to pursue research careers. Business Courier) Cincinnati Children’s full-time in 1963, as the founding

14 15 “ I remember telling my daughter Jori, when she was 14 years old, that she would not be able to eat food anymore,” recalls Ellyn Kodroff. “We sat at the kitchen table and sobbed as she took small sips of the vile-tasting formula, the only thing she could now have.”

Jori, now 20, has an eosinophilic gastrointestinal disorder “Food is far more than just nourishment,” says Karen (EGID). She and her parents travel to Cincinnati Children’s Philip, whose 12-year-old daughter, Grace, lives with an from Chicago every three months so that she can be treated EGID. “It is an expression of our cultures and traditions. by the Cincinnati Center for Eosinophilic Disorders (CCED), To have to view something so life- and soul-sustaining led by Marc Rothenberg, MD, PhD. as a physical threat is daunting and, at times, exhausting.”

Cincinnati Children’s has become the acknowledged leader Deciphering the Mystery in treating and studying eosinophilic disorders–newly A growing number of patients around the world face the recognized conditions in which the body’s immune system challenge of living with and finding care for eosinophilic treats food as a harmful entity, a foreign invader. conditions. In the last decade, rates of many types of allergic diseases have skyrocketed. EGIDs now affect as In response to food, the body rapidly produces too many many as one in 1,000 people. Though they are more immune cells called eosinophils. The cells attack the common than inflammatory bowel disease and Crohn’s pathway that food takes–esophagus, stomach, intestines disease in children, EGIDs are not yet as widely known Ashton Burke learns about eosinophils during lab day, when patients and other organs. with eosinophilic disorders get to meet researchers and have fun playing and are often misdiagnosed. The eosinophils trigger chronic inflammation, pain and educational games modeled on real research activities. During a recent orientation session for new patients tissue damage. Individuals with EGID suffer from growth at the CCED, several families talked about their problems, stomach cramps, vomiting and diarrhea, and difficulties of finding expert care: “My doctor had only have trouble swallowing. seen one other patient with this condition,” said one. Some patients do well if they eliminate specific foods “You’re kind of a mystery,” said another. from their diet. Others are forced to stop eating all food Deciphering Cincinnati Children’s is at the forefront of deciphering and live on a liquid formula diet. The social, emotional the mystery by bringing eosinophilic disorders to the and psychological effects can be staggering. attention of the medical community, as well as conducting the Mysteries research to understand these conditions and advance care. of Eosinophilic Disorders

17 research,” Dr. Putnam points out. “We’d only be able Transforming the Landscape to look at the end of the chain–the cells under a Today the CCED is the world’s largest, most experienced microscope. We wouldn’t understand the processes.” clinical program for EGIDs, and the most productive research center. As with any new research endeavor, securing funding to pursue new ideas was vital. In addition to traditional It has seen more than 1,000 children and adults since 1999. federal research grant funding, the partnership Families come from across the country and around the and investment of private donors proved essential world seeking hope, healing and a better quality of life. to advance the study and care of EGIDs. The center has brought major research discoveries from From hosting small fundraisers, to securing large-dollar the laboratory bench to the clinic–transforming the support from nonprofits and foundations, to creating landscape for patients living with eosinophilic disorders. Left Lab day is open to patients and family members of all ages. Here a youngster gets his first look through a microscope. advocacy groups and testifying before Congress, First, the CCED’s research in mouse models clarified the Right Marc Rothenberg, MD, PhD (at left), leads the Cincinnati Center for Eosinophilic Disorders. Here he meets with postdoctoral the EGID community quickly established itself research fellow Ting Wen, PhD. nature of these diseases. “Esophagitis used to be thought as an integral part of the CCED team. of as only acid reflux related,” says Dr. Rothenberg. The Kodroff family launched the Campaign Urging Research “Our early studies provided a new paradigm, which for Eosinophilic Disease (CURED), a national advocacy subsequently has been accepted–that esophagitis organization dedicated to raising public awareness of could be an allergen-driven inflammatory process.” The work began in 1999, with one child. At the time, there had been only a few reports in medical EGIDs and funds for research to cure it. The Buckeye journals about patients who were thought to have reflux This discovery led to a now widely practiced Gastroenterologist Philip Putnam, MD, had a new patient Foundation, which is managed by the Philip family, also disease but did not respond to medication and had elevated treatment approach: anti-inflammatory drugs in clinic. A biopsy sample of the child’s esophagus showed supports the CCED’s work. “It was a smart investment,” eosinophils. Not much was known about the condition. for eosinophilic esophagitis. a lot of eosinophils. says Karen. “Dr. Rothenberg had the infrastructure The Cincinnati Children’s team wanted to understand needed to make a meaningful impact on the disease. The CCED conducted the first controlled clinical trial He consulted with Dr. Rothenberg, director of the Division more about these mysterious conditions: How to recognize We knew our investment would yield results.” to test this approach. Today, two anti-inflammatory drugs of Allergy/Immunology, who had done extensive basic them. How to diagnose them. The underlying biological are routinely used to control symptoms, and others are research on eosinophils and their role in triggering These two groups have become transformational pathways. How to make life better for patients who suffer under development. allergic inflammation. partners, donating more than $4 million to advance with them. the study and care of EGIDs at Cincinnati Children’s. In another important contribution, the CCED advanced That first patient at Cincinnati Children’s was soon From that small beginning, a comprehensive patient care and understanding of the genetics of EGIDs. followed by others. Dr. Putnam and Dr. Rothenberg “Witnessing their huge commitment is a tremendous research program grew. It was the first of its kind anywhere. started holding a combined clinic and meeting to talk inspiration for our team,” says Dr. Rothenberg. The CCED’s patient data, along with information compiled about what they were seeing. Soon pathologist Margaret Partnering to Advance Research “Their partnership allowed us to pursue new ideas, from its web-based patient registry, revealed that the disease Collins, MD, joined their team. Linking clinical and research expertise was critical to the often less conventional and more far-reaching than occurs in families, suggesting that genetics has a role. program’s success. “We’d be flying blind without the basic would be acceptable to typical funding agencies.”

18 19 Left Jori Kodroff’s family established the Campaign Urging Research for Eosinophilic Disease (CURED). Their partnership has Ellie was diagnosed with eosinophilic esophagitis when she was a baby. At 2½ she was put on the elemental diet. She stopped eating provided critical support for research at Cincinnati Children’s. Right Philip Putnam, MD, talks to 4-year-old Ellie Plummer before food and got all her nutrition from an amino acid formula. After three months, the eosinophils cleared out. Then Dr. Putnam began he performs an endoscopy procedure to test for eosinophils in her esophagus. testing one food at a time to see what foods are safe for her. Today, Ellie can eat six foods, including apples, potatoes and grapes.

In fact, as EGIDs are better understood, many adults– Dr. Rothenberg’s team also has developed a molecular- the clinical research enterprise necessary for truly meaningful Dr. Rothenberg is convinced that “modern genetic approaches including the parents and relatives of some of our based diagnostic test for the disease. The test is currently translation of our findings to patients.” give us the technical capacity to begin to understand why pediatric patients–are finally being diagnosed after being commercialized so that it can be available to people develop the disease–and that will help us develop But more needs to be done to improve outcomes for those a lifetime of struggling with an unrecognized condition. patients everywhere. better diagnostic tests and treatments, and ultimately find who live with EGID. the cure.” The CCED team has done pioneering research to decipher Thanks to these and other achievements, doctors are “We’re making groundbreaking discoveries, but we still the genetic underpinnings of eosinophilic disorders. Dr. better able to reduce patients’ eosinophil levels and The patients and philanthropists who have run this race understand too little,” Dr. Rothenberg says. “A recent Rothenberg’s lab identified and defined the role of several control the disease. with him look forward to the day when they will cross study by our group, showed that children with EGID have genes and proteins involved. the finish line together. Jori is now able to eat a few foods. Her college the lowest quality of life compared with a wide number These discoveries are fueling research for another promising accommodates her very restricted diet by making her of other common pediatric chronic diseases. It’s humbling “I believe Dr. Rothenberg will find a cure,” Ellyn Kodroff treatment approach: antibodies against the proteins IL-5 individualized meals with foods that are safe for her. to see the degree of patient suffering despite all that we’re says. “Then Jori and all the others suffering will have the and IL-13. Dr. Rothenberg led the first trials of anti-IL-5 doing. We need to bring this whole field to a higher level– opportunity to eat and enjoy life again.” Moving to the Next Level and anti-IL-13. Several companies are now pursuing and we’re well positioned to do that.” “The partnership of philanthropists helped us bring these approaches. three major findings from the bench to patients,” says Dr. Rothenberg. “Their investment helped us build

20 21 Alyssa Loftus was a baby when she was diagnosed with a rare disease. Little was known about it, and there were very few specialized clinics in the country to serve patients with it.

Since there was no clinic for her in Cincinnati, Alyssa’s Every patient is affected differently. In some, symptoms parents traveled over 600 miles to take her to the nearest are mild. In others, they’re severe. Though the TS specialist–and he was about to retire. tumors are not cancerous, they can be devastating and life-threatening. Tumors in the brain can cause seizures, Concerned, they reached out to David Franz, MD, autism and profound developmental delay. Tumors can a young neurologist who had trained at Cincinnati destroy kidney and lung function. Children’s and was joining the staff. Would he start a clinic for patients with tuberous sclerosis (TS)? From the beginning, the Cincinnati Children’s clinic set out to offer a new level of care. He said yes, and the institution supported the effort. Patients once were isolated, and care was fragmented. That was 1992. Today that clinic is the largest, most At Cincinnati Children’s, care would be coordinated. comprehensive TS clinic in the world. It is transforming Patients would find lifelong care for all aspects of the disease. care for children and adults with tuberous sclerosis. “All the specialties were there, in one clinic,” says Alyssa’s “It was a huge leap of faith on the part of Cincinnati father. “The multidisciplinary approach was a huge benefit.” Children’s,” says Alyssa’s father, Douglas Loftus. “The whole David Franz, MD, launched a clinic for patients with tuberous sclerosis (TS) team’s commitment to creating a better future for kids In its first 10 years, the program gained recognition in 1992. Today the TS program at Cincinnati Children’s is the world’s largest with TS is just extraordinary.” for clinical excellence. In its second decade, it became and is recognized for clinical excellence and leadership in clinical research. a powerhouse for clinical research. Alyssa, now 21, “has gotten the best care available,” her father says, “and it was right here in our backyard.” The Cincinnati Children’s team has led a series of highly successful trials of the first drug that can alter the course Finding Hope of the disease. These studies resulted in rapid FDA Tuberous sclerosis is a genetic disease that can cause approval of the medicine’s use for brain and kidney Revealing tumors to grow throughout the body–in vital organs, complications of tuberous sclerosis. on the skin and in the eye. the Power The future is no longer hopeless for patients with TS. of a Life-Altering Drug

23 Left When Alyssa Loftus was a baby, her family traveled hundreds of miles to the nearest tuberous sclerosis specialist. Her parents Jonathan Fields underwent two surgeries for brain tumors caused by tuberous sclerosis. When he developed another tumor in 2008, asked Dr. Franz to start a TS program at Cincinnati Children’s. Right Douglas Loftus is deeply grateful for the care his daughter his physician in New York referred him to the clinical trial at Cincinnati Children’s. The medication has reduced the size of the has received, saying, “Alyssa would not have the life she has today if it were not for Cincinnati Children’s.” tumor and given Jonathan a better quality of life. Jonathan’s family moved to Cincinnati last year to be close to care.

From Gene Discovery to Treatment reasoned this drug might reduce the growth of tumors it could fix a genetic condition. Some thought it might the brain, Dr. Franz wanted to try it. Could it also shrink New information about the genetics and molecular in patients with TS. make the tumors worse.” this patient’s brain tumor? It did–leading Dr. Franz and biology of tuberous sclerosis made this progress possible. colleague Darcy Krueger, MD, PhD, to launch a study Their insight opened the door to the first effective treatment. Exceeding Expectations of TS patients with brain tumors. In the 1990s, researchers identified the TS mutation “The families and patients who participated in the trial They began to plan a clinical study of rapamycin and in two genes. By 2000, scientists had discovered that were more than equal partners in this research,” says While monitoring patients’ lungs, Dr. Bissler build the necessary infrastructure for the research. normally these genes control a protein, mTOR, that Dr. Bissler. “They were courageous and altruistic.” found that those with a dangerous lung disease– regulates cell growth throughout the body. The pilot study tested whether rapamycin could reduce lymphangioleiomyomatosis (LAM)–showed improved As a precaution, Dr. Bissler monitored the brain the size of kidney tumors in TS patients and prevent new lung function. LAM affects up to 40 percent of women The research to identify the mTOR pathway was done and lungs of study participants for potential harmful tumors from growing. It was led by nephrologist John with TS. Could rapamycin help them and others with by cancer biologists, but the Cincinnati Children’s TS side effects of the drug. This led the research in Bissler, MD, the world’s leading expert on the kidney LAM? A third trial was launched, led by pulmonologists team seized on the implications for tuberous sclerosis. unexpected directions. complications of tuberous sclerosis. Frank McCormack, MD, from the University of Cincinnati, In individuals who inherit the TS mutation, mTOR One patient enrolling in the kidney trial was found and Bruce Trapnell, MD, from Cincinnati Children’s. As the trial began in 2003, there were doubters. is overactive, causing uncontrolled cell growth and to have a brain tumor. Early results of the kidney study The rare combination of wide-ranging expertise in one tumors. But there was an existing drug, rapamycin, Dr. Franz recalls, “The drug had been used for transplant suggested rapamycin was shrinking kidney tumors. institution, along with a commitment to clinical that inhibits mTOR. The Cincinnati Children’s team and cancer patients. Skeptics asked what made us think Even though it was thought rapamycin did not penetrate

24 25 Dr. Franz recruited 28 patients at Cincinnati Children’s Dr. Bissler presented outcomes of his international for a larger-scale brain tumor study. Alyssa was the 17th follow-up study in February 2012. Kidney tumors to enroll. She had developed a tumor that was rapidly shrunk in all patients who received the drug. 42 percent growing and was facing the possibility of a very difficult of patients experienced a 50 percent reduction in tumor brain surgery. After six months on the medicine, the size. In April 2012 the FDA responded to the data tumor had shrunk 50 percent. In fact, tumors shrunk by granting expedited approval of the drug for non- in all 28 patients. None required surgery for brain cancerous kidney tumors in TS patients. tumors after treatment. Of those with active epilepsy, Within hours, Dr. Bissler started receiving calls from 86 percent had seizures less often. patients around the world wanting to come to Cincinnati These results were reported in 2010. The FDA responded Children’s for care. by granting accelerated approval of the drug for TS patients Left Nephrologist John Bissler, MD (left), is the world’s expert on the kidney complications of tuberous sclerosis. Here he talks with Transforming Lives with brain tumors, while requiring a larger study. research associate Brian Siroky, MD. Right Misty Orlando Barnhart with Jo Coombs, RN. Misty was diagnosed with TS at age 14 The outcome of these clinical trials has been transformational and underwent surgery to remove a tumor-filled kidney at 19, but new tumors grew in her remaining kidney. She found the clinical This next, placebo-controlled trial involved 117 patients for patients and extraordinarily gratifying for the doctors trial at Cincinnati Children’s in 2010. “When I came here, the tumors were so big you couldn’t see my kidney,” she says. “Now you can’t at centers in the US, Canada and Europe. The outcome, and nurses who work closely with them. “I have the best see the tumors, and I have 100 percent normal kidney function. I call it my miracle.” reported at professional meetings in 2011 and published job in the world,” says Jo Coombs, RN. “We see truly in 2012, confirmed the robust results of the initial study. amazing affects of this drug. It changes lives.”

A larger-scale LAM study was coordinated through Says Dr. Bissler, “The families and patients inspire us. a consortium of 13 institutions around the world. It’s deeply gratifying that now we can actually do research, made it possible for Cincinnati Children’s The medicine reduced the size of kidney tumors in all The findings, published in 2011, showed that the drug something that gives them hope for the first time.” to lead simultaneous trials for kidney, brain and lung. participants. When it was stopped, tumors grew again stabilizes lung function and improves patients’ quality in most patients. Of those with LAM, 70 percent had “I get passionate when I talk about it,” Doug Loftus In each case, results exceeded expectations. of life. In 2012, a citizen’s petition requesting accelerated improved lung function that was partially sustained even acknowledges. “Alyssa would not have the life she has approval of the drug for treating LAM was filed with Finally, An Approved Drug Therapy after the medicine was stopped. today if it were not for Cincinnati Children’s.” the FDA. Meanwhile multicenter research to confirm Results of all these trials have been reported at professional These initial findings supported the idea that inhibiting the study results are in progress. meetings and in major medical journals, beginning in mTOR is an effective treatment, and led to larger follow- 2006 when Dr. Franz published data for the first five up studies. patients with brain tumors to be treated with rapamycin. Tumor size decreased in all patients. Dr. Bissler organized a placebo-controlled trial of kidney tumors. The national TS Alliance spread the word Results of a two-year study of patients with kidney tumors, that Cincinnati Children’s was recruiting participants. LAM or both were reported in 2008. Participants received 118 patients in 11 countries enrolled. the medicine for a year, followed by a year without it.

26 27 Charlotte Long is all smiles as she watches her grandson run and play at Cincinnati’s beautiful new Washington Park. “It’s wonderful to see him,” she says. “Last summer was really bad. He was sick a lot and couldn’t play outside.”

Antonio Long, 4, suffers from asthma. Exercise is one health care nurses, inpatient and outpatient services, of the triggers that starts him coughing and wheezing. hospital staff and community partners.

Before his asthma was under good control, breathing Knowledge and confidence problems brought Antonio to the emergency department For Antonio, the path to a better quality of life began last Antonio Long was able to play outdoors this summer because (ED) several times, and his grandmother, who is his guardian, January, during a routine visit to the Pediatric Primary his asthma is under control, thanks to an intensive education missed work to take care of him when he was sick. Care Center (PPCC) at Cincinnati Children’s. and support initiative at Cincinnati Children’s. Antonio and Charlotte enjoyed a happier summer this Because Antonio required emergency care several times year, thanks to an intensive effort at Cincinnati Children’s in 2011, Charlotte was offered the opportunity to to improve care for children with asthma. meet with Lauren Poling, one of two asthma care GUIDING ASTHMA PATIENTS TO coordinators in the PPCC. Targeting community health issues Cincinnati Children’s strategic plan targets four major Says Charlotte, “I’m so glad I took advantage A Better community health issues. Asthma is one of those priorities. of the opportunity.” Asthma is the most common chronic disease of childhood Having a care coordinator means that Charlotte now has and one of the top reasons children are admitted to the a teacher and an advocate to help reduce barriers to care. Q uality hospital. In Hamilton County, Ohio, one in six children Charlotte counts on her if she has questions or concerns. has been diagnosed with asthma. The figure increases “I feel comfortable calling Lauren when I’m unsure what to significantly for children who live below the poverty line. do,” she says, recalling one hot, smoggy day when she called to confirm when to give Antonio his medicine and how of Life Our goal is to help patients improve control of their much to give. Poling was able to review the asthma care asthma to prevent ED visits and hospitalizations. plan developed by Antonio’s provider and give her guidance. The work is being accomplished through a large-scale Poling also referred Charlotte to another service that collaboration of primary care doctors and pulmonary made a difference: the Asthma Home Health Pathway. disease specialists, asthma care coordinators and home Since 2010, Cincinnati Children’s home health nurses

29 a month’s supply of medicine and a copy of the child’s hospitals and organizations across the community to marshal asthma care plan. health information technology to improve asthma care. The Department of Health and Human Services launched In another improvement on the inpatient units, respiratory the Beacon Community Program in 2010 with grants to therapists now conduct an asthma risk assessment, using 17 communities, which are models for innovation using a checklist embedded in the hospital’s electronic medical information technology to tackle leading health problems. record. The assessment identifies families who would benefit The Greater Cincinnati HealthBridge collaboration is from an asthma care plan, education during the hospital focusing on asthma and diabetes. stay, participation in the Asthma Home Health Pathway or referral to community resources. In March, HealthBridge introduced an ED Admit Alert System that sends electronic alerts to primary care The same risk assessment tool is used by asthma care physicians when their patients with asthma or diabetes Left Because Antonio needed emergency care several times in 2011, he was referred to the asthma care coordinator in the Pediatric coordinators in our primary care clinics to assess high- visit the emergency room in any of 21 area hospitals. Primary Care Center. Right Asthma care coordinator Lauren Poling (right) talks with Mona Mansour, MD, in the Pediatric risk patients and by our home health care nurses during Primary Care Center. home visits. Mona Mansour, MD, heads the Beacon program for the Cincinnati Children’s primary care clinics. She notes that When conventional treatment, care coordination and “having regional alerts made us aware of patients who are education aren’t enough, the hospital’s Asthma Center offers eligible for asthma care coordination because of visits to intensive, specialized care by pulmonary disease experts. have visited over 500 families to provide asthma care “Education is everything,” Charlotte says. “I know providers outside of the hospital. It allows us to reach out teaching in the home. I’m doing it right, and Antonio was learning with me. Partners in the community to these patients, regardless of where they go for care.” He knows how many puffs to take.” Work to improve outcomes for children with asthma extends Cheryl Patterson, RN, visited Charlotte and Antonio All of these initiatives are keeping kids out of the hospital. to collaborations with many partners in the community. six times over six months to reinforce the education A bundle of interventions Dr. Mansour reports that children admitted to the hospital Charlotte received in the hospital. Antonio’s asthma is under much better control, thanks One effort is a school-based asthma initiative at Rockdale for asthma are now 50 percent less likely to be readmitted to education and support that gave Charlotte the skills and South Avondale elementary schools, both located She helped Charlotte identify things in the environment or to be seen in the ED within 30 days, and are 23 percent and confidence she needs to manage his care. near our main campus in the Avondale neighborhood. that can trigger Antonio’s asthma. She taught her to less likely to return within 90 days. For high-risk children look for early signs of an asthma episode, so she can give The asthma initiative also includes approaches designed Another is a long-standing asthma initiative with 38 who receive asthma care coordination in our primary care Antonio medicine to stop the attack from getting worse. to meet other challenges families face. community-based pediatric practices that are members clinics, the average number of days between ED visits or She reviewed the difference between controller medicine, of Tri State Child Health Services, a physician hospital hospital admission has gone from 173 to 325 days. An Asthma Inpatient Task Force, led by hospitalist Jeffrey which is given daily to reduce inflammation and prevent organization. Collectively these practices serve 13,000 Simmons, MD, and Asthma Center director Carolyn The numbers are impressive. But nothing is more flare-ups, and rescue medicine, which is given as a fast- children with asthma in Greater Cincinnati. Kercsmar, MD, spearheaded efforts to improve families’ impressive to Charlotte Long than watching Antonio acting treatment for wheezing and shortness of breath. access to asthma medications at home. Children who’ve And as a participant in the Greater Cincinnati Beacon run through the park. And she coached Charlotte on how to fit the inhaler mask had a hospital stay due to asthma now go home with Collaboration, Cincinnati Children’s is working with correctly so Antonio gets all the medicine into his lungs.

30 31 MAKING A DIFFERENCE

THE CONVALESCENT HOSPITAL FOR CHILDREN Left Project SEARCH founder Erin Riehle, MSN, RN (center), with program graduates (l-r) Eric Johnson, Paul Wilson and EVOLVING, EDUCATING, EMPOWERING Mary Bodle. Right Project SEARCH graduate Jill Frambes works as a sterile processing technician at Cincinnati Children’s.

The hallmark of a successful organization is being nimble Hospital for Children has continuously evolved to meet The program partners with schools and a diverse cadre coupled with a passionate program leader and supported enough to meet the changing needs of the community. the most pressing needs of children and teens in our of employers to transition students with special needs by a world-class organization, has created amazing outcomes. That is exactly what the Convalescent Hospital for community and beyond. from high school to meaningful employment. Project Project SEARCH has expanded to more than 200 programs Children has done for more than 180 years. While SEARCH opens new doors for its graduates and allows “Cincinnati Children’s and the Convalescent Hospital in hospitals and businesses in 42 states and seven countries. it closed its doors as a separate hospital a decade ago, them to establish independence and build self-esteem. for Children have an impressive history of championing More than 2,500 students participate in the program the Convalescent Hospital has opened thousands more the care of children,” says Convalescent Hospital board “What began with the vision and determination of one worldwide each year, with approximately 67 percent doors through its formal partnership with Cincinnati member Pam Terp. “Today, we are working together person has grown into a program that provides a future obtaining full-time employment by graduation. Children’s, bringing hope and healing to children and to meet the complex needs of young adults with and a purpose to thousands of people with disabilities,” families in their time of need. “The Convalescent Hospital is very proud to partner with developmental disabilities.” says Marie Huenefeld, a Convalescent Hospital board Cincinnati Children’s in this program,” Marie says. “It has From responding to the needs of children orphaned by member and strong supporter of Project SEARCH. Project SEARCH is one of the more recent programs been a thrill for all of us connected to Project SEARCH a cholera epidemic in the 1830s to providing a resource for “One of the best parts is that so many former Convalescent to benefit from the support of the Convalescent Hospital. to watch the growth and impact it has had not only in children suffering with chronic illnesses in the 1930s; from Hospital children have benefited from the program.” Founded at Cincinnati Children’s more than 15 years Cincinnati, but across the US and around the world.” funding research to battle respiratory distress in premature ago, Project SEARCH is an internationally recognized job Convalescent Hospital’s investment in Project SEARCH infants in the 1980s to supporting the underserved needs training program for people with significant disabilities. has been instrumental to its success. Their partnership, of patients with mental illness in the 1990s, the Convalescent

32 33 As a nonprofit hospital and research center, advance treatments and change the outcome Cincinnati Children’s relies on friends like you for children in Cincinnati, across the nation to provide hope and healing to the children and around the world. and families entrusted to our care. ParTNERSHIP We are profoundly grateful to those who have MAKES THE Your partnership provides seed money to develop chosen to partner with Cincinnati Children’s new programs and services. Your support improves to advance discovery and help bridge what the quality, safety and reliability of pediatric happens in our research labs into improved healthcare. Your investment provides funding treatments and care. Together, we are Difference for innovative research to prevent disease, improving child health.

GIFTS TO CINCINNATI CHILDREN’S Fiscal year 2012: July 1, 2011–June 30, 2012

UNRESTRICTED (21%) RESEARCH (41%) Supports the most pressing needs Advances groundbreaking discoveries that will improve of the medical center. care for kids in our community and around the world.

$6,376,775 $11,805,512 $12,730,129

PATIENT CARE (38%) Provides expert family-centered care TOTAL: $30,912,416 to all children entrusted to our care.

As a nonprofit hospital and research center, we are grateful for all gifts made to Cincinnati Children’s. Unless otherwise noted, this report lists all donors who gave $500 or more in fiscal year 2012 (July 1, 2011 through June 30, 2012). We have made every effort to be accurate and complete with this listing. Should you find an error or omission, please call the Department of Development at 513-636-6347.

35 DONOR RECOGNITION

Kohl’s Department Stores Dr. and Mrs. Joseph A. Pichler Estate of Louis M. Sloan Leukemia and Lymphoma Society- The Procter & Gamble Fund Hannah Jo Smith Research Southern Ohio Estate of Lova D. Riekert for Leukemia Foundation The H.B., E.W., and F.R. Luther Estate of Dr. George Rieveschl Jr. Estate of Joseph S. Stern Jr. Charitable Foundation John J. & Mary R. Schiff Foundation Estate of Ralph J. Stolle Ruth Lyons Children’s Fund The Robert C. and Adele R. Schiff The Sunshine Charitable Foundation Cornerstone Contributors March of Dimes Foundation Family Foundation, Inc. Mrs. Mary Lou Tecklenburg These generous supporters have made gifts to Cincinnati Children’s totaling $1 million or more. Because of their partnership, Marriott International Estate of Leroy E. Schilling Mr. G. Richard Thomas Cincinnati Children’s continues to be a leader among pediatric hospitals. Our research pioneers are changing the way doctors Dr. and Mrs. Lester W. Martin Roger P. Schlemmer Toyota Motor North America, Inc. all over the world care for children. Our clinicians are able to provide state-of-the-art, family-centered care, and countless Mr.* and Mrs. Manuel D. Mayerson Charlotte R. Schmidlapp Fund Western & Southern Financial lives have been saved. Dr. and Mrs. Robert L. McLaurin Jacob G. Schmidlapp Trusts Group Masters Dr. and Mrs. C. Nelson Melampy Marge & Charles J. Schott Foundation Louise A. Williams Trust The Oxley Foundation Michael M. Shoemaker Trust Estate of Louise S. Wilshire Dr. and Mrs. Ira A. Abrahamson Jr. Cincinnati Center for Developmental Fondation Leducq Ms. Jean L. Abrahamson Disorders Foundation Mr. Robert B. Gardner American Heart Association Mr. and Mrs. Thomas G. Cody Sr. Bill and Melinda Gates Foundation Anonymous (8) Mr. Reed L. Coen General Electric Evendale Employees’ MAKING A DIFFERENCE Association of Volunteers The Convalescent Hospital for Children Community Service Fund Dr. and Mrs. Richard G. Azizkhan The Cooperative Society Emma Margaret Goldman Trust Dennis and Ann Flaherty Patricia Heekin Briggs Dr. and Mrs. Alvin H. Crawford Estate of Irving Goldman Hemophagocytic lymphohistiocytosis (HLH)–two words to improve care for those diagnosed and to help families CURED The Greater Cincinnati Foundation Mrs. Lela C. Brown that changed Dennis and Ann Flaherty’s life forever. facing HLH, the Flahertys have provided seed funding Buckeye Foundation Charles H. Dater Foundation Marjory J. Johnson Trust Their son William was diagnosed with this life-threatening for the HLH Center of Excellence at Cincinnati Mr. and Mrs. David G. Bunning Boomer Esiason Foundation Ms. Lyn M. Jones immunodeficiency disorder when he was only 3 years old. Children’s. The center is focused on four pillars– Robert Rogan Burchenal Foundation James M. Ewell Charitable Junior Co-Operative Society After a long battle that included a bone marrow transplant, research, education, clinical care and family support. Estate of Dorothy S. Campbell Remainder Trust Ida C. Kayser Trust William is now a happy and healthy 8-year-old, but Dennis “This center will significantly change the outcome Mr. and Mrs. Lee A. Carter Fifth Third Bank Robert T. Keeler Foundation and Ann haven’t forgotten how daunting the journey to the for families facing this disease through earlier detection, cure can be. treatments and family-focused support,” Dennis says. Cincinnati Children’s Employees Mrs. Barbara J. Fitch Dorothy M. M. Kersten Trust “This journey can be extremely dark at times, and the The Children’s Heart Association The Flaherty Family Kindervelt of Children’s Hospital Determined to find a way to bring more awareness about HLH Center of Excellence at Cincinnati Children’s will Food Allergy Initiative Medical Center the newly recognized disorder to the medical community, Children’s Miracle Network Hospitals be a beacon of hope.”

36 37 Individuals and Family Foundations Anonymous (6) Mr. Dee Ellingwood and Andrea Lerner Levenson Cincinnati Children’s is able to change the outcome for families because of our long-standing partnership with donors. We thank Dr. and Mrs. Ellis Arjmand Ms. Kaycee McGinley Dr. Stephen Levitt the many patients, families, staff and friends who have made charitable gifts to support our work. Each and every donor makes Dr. and Mrs. Richard G. Azizkhan Mrs. Barbara J. Fitch LKC Foundation a difference in the lives of the families we serve. Ted and Kim Beach Mr. and Mrs. Walter C. Frank Jerry and Tyra Markham Mr. Leonard H. Berenfield Mr. and Mrs. Thomas W. Gougeon Ms. Dee A. Martin Dr. Janet A. Borcherding Robert Gould Foundation Mrs. Martha H. McGraw Mr. and Mrs. Brian K. Bourgraf Mr. Donald L. Grant Mr. and Mrs. Gene I. Mesh $1,000,000 + Mrs. Mary Lou Tecklenburg Mr. and Mrs. Scott J. Hamlin Mr. and Mrs. Elroy E. Bourgraf Sr. Mr. and Mrs. James J. Gusweiler Mitch’s Mission The Flaherty Family Mr. G. Richard Thomas Mr. and Mrs. Terence L. Horan Mr. and Mrs. William C. Bray Mr. and Mrs. Clinton A. Haynes Ms. Gail Norris Dr. and Mrs. Robert L. McLaurin Nancy and David Wolf Mr. and Mrs. David C. Horn Mr. and Mrs. Thomas W. Brennaman Mr. and Mrs. Richard L. Hildbold Ohio River Valley Combined Dr. and Mrs. Joseph A. Pichler Richard L. Hunt* Mr. and Mrs. Michael S. Cambron Mr. and Mrs. Ronald P. Ipach Federal Campaign $50,000 – $99,999 The Sunshine Charitable Foundation Mr. and Mrs. Donald J. Jaquet Mr. and Mrs. Lee A. Carter Marianne and Donald James Jane and Rob Portman Anonymous (2) Mr. and Mrs. Mitchell S. Meyers Dr. and Mrs. Brian D. Coley Mr. Brandon J. Janszen Mr. and Mrs. Andrew B. Quinn $100,000 – $999,999 Henry and Elaine Fischer Mrs. Nancy M. Miller Dr. Robin T. Cotton and Mrs. Molly E. Kaplan* Dr.* and Mrs. Joseph L. Rauh Anonymous (3) Dr. and Mrs. David L. Goldfarb Donald J. Moeggenberg* Ms. Cynthia M. Fitton Mr. and Mrs. Jeffrey Karsen Mr. and Mrs. Andrew S. Ritch Mrs. Lela C. Brown Mr. and Mrs. Timothy L. Mathile Namaste Foundation The Crosset Family Fund Walter and Olivia Kiebach Dr. and Mrs. Jeffrey Robbins Mr. and Mrs. Thomas G. Cody Sr. Sophie’s Angel Run LLC. Mr. and Mrs. Franklin W. Reilly Mr. and Mrs. Roger W. Dean Charitable Foundation Trust Mr. and Mrs. Gerald J. Robinson CURED Mr. Richard A. Weiland Mr. and Mrs. Michael J. Sepela Mr. and Mrs. Thomas J. DiMarco Ellen and Mark Knue Dr. Frederick C. and Michael and Suzette Fisher $25,000 – $49,999 Rudolph and Marie Simich The Dodson Foundation Inc. The Ronald Kuntz Family Mrs. Susan H. Ryckman Food Allergy Initiative Annie Wallingford Family Foundation Dr. Dennis Drotar and Denise and John Kuprionis Ms. Donna L. Schiff Joseph E. Ghory Allergy Fund of Anderson Foundation Mr. and Mrs. Eric L. Smidt Dr. Peggy A. Crawford Dr. C. Dean Kurth Alan and Cheryl Schriber The Greater Cincinnati Foundation Elizabeth Mendenhall Mrs. Mauri Willis Liam’s Lighthouse Foundation Anderson Foundation Mrs. Jean E. Wommack Neena Rao Charitable Corporation Mr. James M. Anderson and The Craig Young Family Foundation John J. & Mary R. Schiff Foundation Reverend Marjorie C. Anderson The Robert C. and Adele R. Schiff Anonymous (4) $10,000 – $24,999 Family Foundation Inc. Children’s Circle of Care Dr. Nathaniel A. Chuang and Mr. and Mrs. Samuel M. Allen Mr. William J. Sinkula Dr. Jeannie S. Huang Alpaugh Foundation Individuals, couples and family foundations that gave $10,000 or more during calendar year 2011, or whose cumulative gifts Hannah Jo Smith Research Clack Foundation Inc. Amgis Foundation have exceeded $1 million, are recognized as members of Children’s Circle of Care. Founded in 1995 by North America’s most for Leukemia Foundation Dr. and Mrs. Alvin H. Crawford Mr. and Mrs. Robert D.H. Anning prestigious children’s hospitals, Children’s Circle of Care honors the major benefactors of the 25 leading pediatric hospitals.

38 39 Skyler Foundation Mr. and Mrs. Ronald K. Chasteen George W. and Elizabeth W. Mrs. Mary Jane Schubert Dr. Lesley L. Breech and Dr. Cheryl L. Hoying and Mr. and Mrs. Mark D. Smith Madge Chidlaw* Kelly Foundation Schwab Charitable Fund Dr. Jack B. Basil Mr. Joseph L. Hoying Dr. Joseph T. Stegmaier and Dr. and Mrs. Daniel I. Choo Mr. and Mrs. William M. Kent Mr. and Mrs. Marvin H. Schwartz Dr. Rebeccah L. Brown and Mr. and Mrs. James L. Jaeger Mrs. Barbara R. Sporck-Stegmaier Gerry and Bill Cowlin Foundation Mr. and Mrs. Daniel E. Kincaid The Scoliosis Foundation Mr. Dan O. Jones Mr. Thomas A. Johnson Ms. Elizabeth A. Stautberg Mr. and Mrs. James R. Cummins Mr. and Mrs. Thomas E. Kinman Mr. and Mrs. Joseph C. Seta Mr. and Mrs. William B. Brown Jr. Mr. and Mrs. Terry S. Karageorges The Robert and Christine Steinmann Mr. and Mrs. Thomas J. Danis Mr. and Mrs. Daniel P. Klare Mr. Jay Shaw Mr. and Mrs. Danny R. Ms. Joyce J. Keeshin Brummett-Mason Family Foundation John & Shirley Davies Foundation Dr. and Mrs. Frederick W. Koch Mr. and Mrs. David L. Singer Mr. and Mrs. Roy C. Kiessling Mr. and Mrs. Robert K. Citrone Mr. and Mrs. Harold W. Still Colin J. Dembo Memorial Foundation Edward T. and Blanche C. Korten Mr. and Mrs. Robert B. Stein Jr. Mr. and Mrs. Jeff Klare Mr. William C. Clasen and Ms. Mr. and Mrs. Peter S. Strange Amy Diamond and Family Charitable Fund Mr. and Mrs. John W. Steinman III Mr. and Mrs. Paul C. Koch Kathleen Winter Mr. and Mrs. Bernard P. Suer Mr. and Mrs. Richard A. Dineen Arthur and Elizabeth Kuhn Fund Mrs. Barbara E. Stern Jay and Karen Kratz Mr. Robert L. Collins The Sutphin Family Foundation Mr. and Mrs. George A. Dunn Jr. Mr. John E. Lanier and Mrs. Mary L. Strutz Dr. Catherine L. Krawczeski and Dr. Sandra J. Degen and The Richard H. Sutphin Dr. Nancy K. and Mr. David A. Eddy Ms. Jane E. Garvey Mr. and Mrs. Davis M. Tapp Mr. Richard A. Krawczeski Family Foundation Dr. Jay L. Degen Mrs. Trudie R. Ficks Mr. and Mrs. Joseph T. Lukens Jr. Mr. Jerome F. Tatar Mr. Michael Kresser JS Turner Family Foundation Mr. and Mrs. Robert E. Donelan Jr. Mrs. Roberta S. Fisher Mr. and Mrs. Millard H. Mack Mr. and Mrs. Alexander Thomson III Dr. Ann W. Kummer Dr. and Mrs. Daniel von Allmen Graw Jr. Ms. Sonia L. Donoher Donald and Deborah Gilbert Anne S. and James J. Mc Max Richard Thornsbury Foundation Mr. and Mrs. Christopher D. Lah IV Mr. and Mrs. Gary W. Wright Dr. Lorah D. Dorn Mrs. Jocelyn H. Glass The Mead Foundation Mr. Alan S. Threlkeld Mr. John LaRocca Mr. and Mrs. Robert S. Yeakle Mr. and Mrs. David F. Dougherty Dr. and Mrs. James M. Greenberg Blanche M. and Herbert A. Metzger Mr. and Mrs. Terry L. Tranter Mr. and Mrs. Jeffrey W. Lazarow YOT Full Circle Foundation Memorial Fund Mr. and Mrs. David W. Ellis III Mr. and Mrs. Thomas T. Gregory Mr. and Mrs. David I. J. Wang Mr. Jie Li Mr. and Mrs. John H. Enneking III Mr. James A. Miller Dr. and Mrs. Philip K. Lichtenstein $5,000 – $9,999 Mr. and Mrs. Harold B. Guttman Mr. Jonathan Zipperstein Morgan Family Foundation Ms. Margaret A. Everist Helen T. Andrews Foundation Mr. and Mrs. Louis B. Guttman Mr. and Mrs. Douglas P. Loftus Dr. Ardythe L. Morrow and $2,500 – $4,999 Mr. and Mrs. Wayne I. Fanta Anonymous Mr. and Mrs. Joseph P. Hayden III Dr. and Mrs. Daniel J. Lovell Mr. Kenneth R. Haag Mr. and Mrs. Michael J. Abbinante Dr. and Mrs. Michael K. Farrell Dr. Diane S. Babcock Ms. Casey Hilmer Dr. and Mrs. Francesco T. Mangano Dr. and Mrs. Martin J. Murphy Anonymous Mrs. Sandy L. Fritz Drs. Wynndel P. Baldock and Mr. and Mrs. Michael A. Hirschfeld Mr. and Mrs. Michael E. Martin Dr. Arthur M. Pancioli and Dr. and Mrs. Mark C. Ault Mr. and Mrs. William J. Gentner Elisabeth E. Baldock Mr. Michael J. Hoogeveen Mr. and Mrs. Scott Mattis Dr. Rita M. Girard Mr. and Mrs. Michael B. Baughan Mr. and Mrs. Matthew T. Hanson Mr. and Mrs. Andrew L. Berman Dr. Margaret K. Hostetter Mr. Ken May Nina and Edward Paul Ms. Marty Betagole Mrs. Phyllis Harlow Mr. and Mrs. Robert W. Blackmore III Mr. and Mrs. Andrew J. Johnson Dr. Jaclyn W. McAlees and Dr. John P. Perentesis and Dr. Francis M. Biro and John and Carrie Hayden Mr. Marcus McAlees Mr. and Mrs. William B. Brown III The Raymond C. and Dr. Stella M. Davies Ms. Nancy L. Bloemer Family Foundation Ms. Madeleine Burmester Anna T. Johnson Foundation Inc. Dr. and Mrs. John E. McCall Mr. and Mrs. Bernie Rabinowitz Mr. and Mrs. Gary S. Bohn Mr. and Mrs. Paul L. Helpling Dr. and Mrs. Steven C. Carleton Mr. and Mrs. Thomas M. Keckeis Mr. and Mrs. George M. Menyhert Dr. and Mrs. Robert C. Schiff Jr. Mr. and Mrs. Robert A. Bowen Mr. Aaron Hempfling

40 41 Mr. Steven Messer Dr. Parke G. and Dorothy M. Mr. and Mrs. Jeffrey R. Anderson Jr. Mr. and Mrs. Douglas S. Brown Mr. and Mrs. Steven A. Cirino Mr. and Mrs. Daniel H. Demmerle II Mr. Peter D. Morey and Smith Foundation Mr. and Mrs. Rob H. Anning II Mr. James M. Brown Dr. Douglas F. Clapp Mr. and Mrs. Paul DeNicolo Dr. Bernadette L. Koch The Philip Smith Foundation Anonymous (3) Mr. James W. Brown Mr. and Mrs. James W. Cochran Mr. and Mrs. Andrew E. DeWitt Ms. Anne K. Morton Mrs. Violet K. Solomon Mr.* and Mrs. Neil A. Armstrong Dr. Pamela I. Brown Dr. Mitchell B. Cohen and Dr. and Mrs. Thomas G. DeWitt Mr. Todd Moss Mr. and Mrs. Russell L. Speed Mr. and Mrs. James Barter Bruce Family Foundation Dr. Morissa Cohen Mr. and Mrs. William O. DeWitt Jr. Dr. and Mrs. Louis J. Muglia Dr. Lori J. Stark and Mr. and Mrs. Michael L. Bauer Mr. and Mrs. Daniel W. Brummett Mr. and Mrs. Thomas P. Collins Mr. and Mrs. David W. Deye Dr. and Mrs. Charles M. Myer III Mr. Eric A. Grohsgal Mr. and Mrs. Charles E. Baverman Jr. Mrs. Cynthia Burnett Dr. Beverly L. Connelly Dr. and Mrs. Scott E. Dillingham Mr. and Mrs. Suresh Nirody Mr. Daryl Strother Mr. and Mrs. Michael Beard Mr. and Mrs. Stephen R. Burns Mr. and Mrs. Dave Cook Dr. Mark S. Dine Mr. James R. Office Mr. and Mrs. Gary Sullivan Mr. and Mrs. Edward D. Beckman Mr. and Mrs. Frank D. Buttari Mr. and Mrs. Dannah J. Crosby Alex Dinkel Foundation The Richard and Dorothy Mr. and Mrs. Michael J. Sylvester Mrs. Cindi Bedinghaus Mr. and Mrs. Kerry R. Byrne Dr. Michael H. Cynamon and Mr. James R. Doellman Pandorf Foundation Mr. and Mrs. Steve Sylvester Mr. and Mrs. Richard J. Beiting Mr. Michael Camacci and Ms. Wendy Ressler Mr. and Mrs. Michael V. Downing Mr. Ian Pinales Mr. and Mrs. Thomas T. Terp Mr. and Mrs. Stephen J. Beiting Ms. Diana L. Collins Ms. Sarah Dailey Mr. and Mrs. Peter H. Dworjanyn Mr. and Mrs. Paul S. Preston Dr. and Mrs. Thomas U. Todd Mrs. Lois G. Benjamin Mrs. Tiffanne Campbell Mr. and Mrs. Clayton C. Daley Jr. Ms. Lalita Duggal Drs. John and Judy Racadio Dr. and Mrs. Jeffrey A. Towbin Mr. Richard L. Betagole Mr. Stephen S. Campbell Lewis and Marjorie Daniel Foundation Mr. Darryl Echoles Mr. Raja Ram Ms. Robin Uhl Mr. Travis Bible Mr. Thomas J. Cash Mr. and Mrs. Richard Darlington Mr. and Mrs. William R. Eckerle Dr. and Mrs. Stephen M. Rauh Mr. and Mrs. Michael D. Valentine Drs. David and Elaine Billmire Ms. Susanne M. Cassidy Mr. and Mrs. Shailaja Datla Mr. and Mrs. Ian S. Edwards Mr. William R. Remke Mr. and Mrs. Ray Van Der Horst Mr. and Mrs. Erik Bjerke Ms. Carrie A. Cassis Mrs. Katharine M. Davis Mr. and Mrs. Barry N. Ehrnschwender Ms. Erin Riehle Dr. and Mrs. Jeffrey A. Whitsett Dr. Melodie G. Blacklidge and Mr. and Mrs. Michael J. Cebo Dr. and Mrs. Adekunle H. Dawodu Mr. and Mrs. Richard H. Elder Rose Family Fund Mr. Brian R. Wildman Mr. Kenneth Dunn Mr. and Mrs. Scott L. Chandler Mr. and Mrs. Patrick J. Dearing Gene and Neddie Mae Elkus Mrs. Susan Rutkowski Mr. and Mrs. Jay V. Wittenbaum Mr. Thomas H. Blalock Dr. Barbara A. Chini and Mr. and Mrs. Charles A. DelGrande Family Foundation Mr. and Mrs. James A. Saporito Mr. and Mrs. James M. Blanton Mr. Paul V. Janavicius Mr. and Mrs. Randall L. Delk Mr. and Mrs. John H. Elms $1,000 – $2,499 Mr. and Mrs. Morgan S. Schafer Mr. and Mrs. Donald E. Able Mr. and Mrs. Arlen D. Bockhorn Mr. and Mrs. Brett Schappacher Mr. and Mrs. John T. Acklen Mr. and Mrs. Damon D. Bowling Mr. Matt Schmitz Mr. and Mrs. James R. Adams Mr. and Mrs. James P. Boyce Mr. and Mrs. Jeffrey N. Schner Dr. Evaline A. Alessandrini and Dr. Rebecca C. Brady Mr. and Mrs. Gregory W. Schube Mr. Thomas F. Alloy Mr. and Mrs. Richard D. Branson Schubert Society Mr. and Mrs. Gerald S. Skidmore Dr. Raouf S. Amin and Mrs. Eleanor J. Brenan Employees of Cincinnati Children’s who give $1,000 or more in a fiscal year are recognized as members of the William K. Catharine S. Smith, C. Kenneth Smith, Dr. Amal H. Assa’ad Dr. Maria T. Britto Schubert, MD, Society. Named for the beloved and greatly missed pediatrician and dedicated leader of the medical center, and Philip S. Smith Family Fund Mr. and Mrs. Aaron L. Broomall Mr. Robert A. Anderle this society honors those who follow Dr. Schubert’s example of generous philanthropic support.

42 43 Dr. and Mrs. Richard A. Falcone Jr. Mrs. Kimberly Goins Ms. Mary Maureen Heekin Mr. and Mrs. Tony L. Johnston Susan and Roy Kulick Dr. Mona E. Mansour Mr. and Mrs. D. Vincent Faris Mr. and Mrs. Kevin C. Gold Mr. Paul Heiman Dr. and Mrs. Blaise V. Jones Mr. and Mrs. Donald P. Laden Mr. and Mrs. Randall G. Marsh Ms. Jena Feichtner Mrs. Amanda J. Goldsmith Mr. and Mrs. Jeffrey K. Heinichen Mr. and Mrs. David J. Josephic Mr. Chris D. Lahna Mr. and Mrs. Luke S. Martin Mr. and Mrs. Thomas B. Feldmann Dr. and Mrs. Stuart L. Goldstein Dr. and Mrs. Michael A. Helmrath The Juilfs Foundation Dr. Tal Laor Mr. and Mrs. Alexander R. Marx Mr. and Mrs. Thomas M. Finn Mr. and Mrs. Robert P. Goodwin Mr. and Mrs. William J. Hemingway Dr. Karen A. Kalinyak and Mr. and Mrs. Joseph Lapinsky Mr. and Mrs. Clayton L. Mathile Mr. and Mrs. Marc E. Flick Mr. and Mrs. Bradley M. Govert Mr. and Mrs. Keith Henize Mr. Joseph G. Martin Mr. and Mrs. John P. Larson Mr. and Mrs. Brian May Mr. and Mrs. Timothy J. Fogarty Mr. Louis C. Graeter II Mr. and Mrs. Daniel F. Henke Mr. and Mrs. Carl F. Kalnow Ms. Michele Laumer Mr. and Mrs. Joshua K. Mayers Mr. and Mrs. William W. Ford III Mr. and Mrs. Michal L. Grau Mr. and Mrs. Robert J. Herman Mr. and Mrs. Bill E. Katz Mr. and Mrs. Simati L. Laupola Dr. and Mrs. David C. Mayhaus Mr. and Mrs. William A. Forrester Mr. and Mrs. Frederick H. Gribbell The Herzog-Beckman Foundation Ms. Stacy Katz Mr. Eric Lavender Dr. and Mrs. John J. McAuliffe III Mr. Gary Franke Mr. Thomas W. Griffiths Mr. Ronald G. Hess Dr. and Mrs. Andrew V. Kayes Mr. Ernest Lawhorn Mr. John McCann Mr. and Mrs. James R. Frebis Mr. and Mrs. Thomas N. Haas Dr. and Mrs. James E. Heubi Dr. and Mrs. Gary L. Keller Ms. Ruth Lebow Dr. and Mrs. James J. McCarthy Mr. and Mrs. Stephen F. Frey Mr. and Mrs. Michael J. Habel Mr. Ron Hicks and Mr. and Mrs. John A. Kerechek Mr. William T. Lecher Mr. and Mrs. Kevin T. McCormick Dr. and Mrs. Harry F. Fry Ms. Jamilah Hackworth Ms. Michele Fronckiewicz Mr. Stephen J. Knox and Mr. and Mrs. John W. Leikhim Mr. and Mrs. Mark B. McDonald Mr. and Mrs. Christopher S. Frye Mr. and Mrs. Gary G. Hagopian Mr. and Mrs. James L. Hill Ms. Betsy Kiley Dr. and Mrs. Marc A. Levitt Mr. Robert W. McDonald Mr. and Mrs. William J. Fussinger Hainline Family Foundation Mr. and Mrs. Max W. Hillman Jr. Mr. and Mrs. Steven C. Kimball Mrs. Barbara G. Lewis Mr. Powell McHenry Mr. and Mrs. John A. Gaskey Ms. Joy E. Hamilton Mr. and Mrs. Harlyn J. Hubers Dr. Eileen C. King and Mr. and Mrs. Jeffrey A. Litmer Ms. Vicki M. McIver Mr. Dennis W. King Ms. Joan M. Gates Mr. and Mrs. Jason E. Hammann Mr. and Mrs. Robert C. Hughes Dr. Mitchel D. Livingston and Ms. Sharon M. McLeod Dr. and Mrs. John W. Klekamp Dr. and Mrs. Rodney P. Geier Ms. Michele Hanson Mrs. Martha G. Huheey Mrs. Carol Livingston Dr. and Mrs. Daniel McLinden Ariana Knue Dr. Michael J. and Ms. Roberta S. Harding Ms. Mary Jo Hutchins Mr. John J. Locaputo Mr. and Mrs. Arthur F. McMahon III Carly Knue Dr. Janelle A. Gelfand Dr. Parameswaran Hariharan and Ms. Tracy Inman Ms. M. Anne Longo Dr. Charles T. Mehlman and Mr. Kevin E. Gessner Dr. Lalitha Hariharan Mr. and Mrs. James H. Irvine Zachary Knue Dr. Sarah L. Lopper and Dr. Elsira M. Pina Mr. and Mrs. Karl J. Gieseke Robert & Helen Harmony Fund Mr. and Mrs. Brian R. Jacob Mr. and Mrs. Peter C. Koch Mr. Jeffrey A. Lopper Mrs. Jodi Meister Mr. and Mrs. William S. Giesler For Needy Children Mr. and Mrs. Harold Jarnicki Mr. and Mrs. Louis Koenig Mr. George B. Lott and Dr. and Mrs. C. Nelson Melampy Ms. Barbara L. Glassmeyer Mr. Danny D. Harris Mr. and Mrs. Richard T. Jinks Mr. and Mrs. Chase M. Kohn Ms. Barbara N. Wurth Ms. Kristin R. Melton Ms. Julie M. Glassmeyer and Mr. and Mrs. John Hartz Dr. and Mrs. Alan H. Jobe Mr. and Mrs. Curt W. Koslovsky Mrs. Elizabeth Lovett Grover Ms. Patricia L. Messmer Mr. Paul D. Berlage Mr. and Mrs. Timothy J. Hastings Mrs. Arlyn T. Johnson Dr. Alice Kreisle and Mr. Jon Bormet Dr. Maurizio Macaluso Mr. and Mrs. Matthew J. Meyer Dr. and Mrs. Jack L. Gluckman Mr. and Mrs. Christopher S. Hatcher Ms. Patricia A. Johnson Mr. and Mrs. David J. Krier Mr. and Mrs. Carlos F. Mahaffey Mr. and Mrs. Edward J. Millar Mrs. Deane B. Godfrey Mr. and Mrs. John L. Hausfeld Mr. and Mrs. Rick L. Johnson Mr. Gerard Kroger Mr. and Mrs. Kenneth M. Mailender Mr. and Mrs. J. Michael Miller Mr. and Mrs. Robert A. Goering Mr. and Mrs. Keith A. Hazlewood Mr. Robert A. Johnston Mr. and Mrs. Joseph M. Kroner Mr. David B. Malik Mr. Kelly T. Miller

44 45 Ms. Maura L. Moran Mrs. Christine Opdycke Ms. Judith R. Ragsdale Mr. Tim and The Honorable Mr. Steve M. Singer Ms. Terri L. Thrasher Mr. George E. Morgan III Dr. and Mrs. Joseph J. Palermo Jr. Mr. and Mrs. Robert D. Rands Kathleen Rodenberg Mr. and Mrs. Steve Singleton Mr. Timothy M. Timmers Dr. and Mrs. Michael L. Mucenski Mr. and Mrs. Ronald A. Panioto Jr. Mr. and Mrs. Doug B. Rawlings Mr. and Mrs. John W. Rogers Mr. and Mrs. James A. Sluzewski Ms. Patricia M. Tobergte Dr. and Mrs. Stephen E. Muething Dr. Ruben Papoian and Ms. Lynn Briggs Red Bird Hollow Foundation Ms. Nicole R. Rotunno and John G. Smale* Mr. and Mrs. Paul H. Tobias Mr. and Mrs. Alan W. Mullins Mr. and Mrs. Paul A. Pappenheimer Jr. Dr. Pramod P. Reddy and Mr. Robert F. Rogas Mr. and Mrs. Tim Smallwood Dr. Joseph C. Todd Dr. Joel N. Myers Mr. and Mrs. Christopher J. Parker Dr. Usha P. Reddy Mr. and Mrs. Jerry L. Rutherford Mr. Christopher J. Smith Mr. and Mrs. Mark W. Townsend Mr. and Mrs. John C. Myers Dr. Alice A. Passer and Richard D. Reis Family Foundation Mr. and Mrs. William E. Rutz Solomon/Rau Family Mr. and Mrs. Glenn A. Travis Mr. Jason W. Napora and Mr. Barry I. Krieger Mr. and Mrs. Gregory W. Renzenbrink Dr. and Mrs. Howard M. Saal Dr. and Mrs. Imre Solti Mr. and Mrs. Anthony M. Sansalone Ms. Alison Momeyer Dr. and Mrs. William S. Pease Mrs. Gayle P. Riemer Mr. and Mrs. Anthony C. Saladonis Mr. and Mrs. James W. Sowar Jr. Mr. and Mrs. Charles W. Turner Jr. Mr. and Mrs. Timothy E. Needham Dr. and Mrs. Robert C. Pence Mr. and Mrs. Brad A. Rife Mr. and Mrs. Michael E. Saxion Paul and Karen Sparling Mr. and Mrs. Douglas Tyger Dr. David P. Nelson Mrs. Sandra S. Perry Dr. Isidro Risma and Mr. and Mrs. William R. Saxton Mr. and Mrs. Frederick S. Spohr Dr. Judith B. Van Ginkel Mr. and Mrs. Hale Newman Mr. and Mrs. James P. Pilcher Dr. Kimberly A. Risma Ms. Anne Scharff Dr. and Mrs. S. Andrew Spooner Mr. Herbert L. Venable and Ms. Laura C. Nixon Mr. and Mrs. John J. Planes Jr. Mr. and Mrs. Eppa Rixey IV Mr. and Mrs. Alan M. Schell Dr. and Mrs. Paul E. Steele Ms. Julia Abell Mr. and Mrs. John Nordmeyer Mr. and Mrs. Kim F. Pleggenkuhle Mr. and Mrs. Danny L. Roark Ms. Mary A. Schell Mr. and Mrs. Joe Steinert Carl S. and Stephanie M. Vorhoff Ms. Debbie H. Ogden Ms. Carrie Pollick Reuben B. Robertson Foundation Mr. Thomas R. Schiff Dr. Mark C. Steinhoff Mr. and Mrs. Christopher and Ms. Lynn R. Olman Mr. Jay R. Purdy Dr. Nicole C. Robinson and Mr. and Mrs. Alan G. Schmidt Ms. Yvonne E. Stepter Kathleen Vuturo Dr. Bryce Robinson Mr. and Mrs. David B. O’Maley Mr. and Mrs. Kevin E. Quill Mr. and Mrs. Stephen J. Schmitz Mrs. Amy Stoll Susan Wade Murphy Dr. David P. Schor and Dr. and Mrs. Arnold W. Strauss Mr. James T. Walker and Ms. Susan M. Elek Ms. Kathleen A. Furlong Mr. Richard Stuart Mr. John T. Schwierling Jr. Mr. and Mrs. Jason A. Walker Mr. and Mrs. Gail R. Stultz MAKING A DIFFERENCE Ms. Elizabeth Schumacher Mr. and Mrs. Brian Sullivan Mr. Richie Walker Ms. Mary Beth Schutter Ms. Kathleen M. Sullivan Mr. and Mrs. John Waltz Joe and Susan Pichler Mr. Christopher M. Scowden Mr. and Mrs. Paul M. Sullivan III Mr. and Mrs. William H. Ward Dr. Robert A. Shapiro and Gary D. Webb Joe and Susan Pichler have known many families whose mental illness, an area of medicine that is often underserved Ms. Regina C. Surgener Dr. Ms. Elaine E. Fink Mr. and Mrs. Brian A. Webb children have received exceptional care at Cincinnati and underfunded. The Pichlers responded with a significant Dr. Alexandra Szabova Ms. Julie Ann Shaw Mr. and Mrs. Andrew A. Webster Children’s, often for conditions that require sophisticated gift in support of the Partial Hospitalization Program, Dr. Nicole M. Tepe and Mr. and Mrs. David L. Shelton analysis and treatment. These experiences led them to talk which provides inpatient therapeutic care for children Mr. Matthew Wortman The Weichert Kranbuhl with Arnold Strauss, MD, chair of the Department of and adolescents in a daily, nine-hour program that allows Mr. John M. Shepherd Family Foundation Mr. James W. Thompson Pediatrics, who told them of the critical need to expand them to go home to their families each night. Mr. and Mrs. Joseph M. Sims Dr. and Mrs. Derek Wheeler Mr. Robert W. Thompson treatment programs for children and teens suffering from

46 47 Mr. and Mrs. Richard H. Wick Dr. and Mrs. Bruce J. Aronow Dr. Daniel T. Brown and Dr. and Mrs. Kerry R. Crone Mr. and Mrs. Kenneth R. Elder Ms. Erin Gore Mrs. Joyce R. Wilhelm Dr. Cindy J. Bachurski Mr. Mark R. Haggard Mr. and Mrs. Charles E. Curran III Dr. and Mrs. Ravindhra G. Elluru Dr. and Mrs. Jack W. Gottschalk Mr. and Mrs. Jeffrey Willett Mr. and Mrs. Timothy J. Bankes Dr. Jennifer M. Brown and Mr. and Mrs. John Curro Mr. Gilbert Embry The Charles M. Grant Foundation Dr. and Mrs. J. Paul Willging Mr. and Mrs. Bernard M. Barbash Mr. Richard T. Brown Mr. and Mrs. Terry L. Davies Mr. and Mrs. Mark A. English Mr. Joseph N. Green Mr. and Mrs. Wayne A. Williams Ms. Cheryl D. Bauer Ms. Kim R. Brown Mr. and Mrs. Craig M. Davis Mr. Jeffrey Engram Dr. and Mrs. John H. Greinwald Jr. Dr. and Mrs. Stephen Wilson Mr. Richard L. Bere Mr. and Mrs. Larry J. Brueshaber Mrs. Kathleen G. Davis Dr. Kelly T. Epplen and Mr. James M. Grodnick Mrs. Roberta Winters Mrs. Mildred Berning Mr. and Mrs. Michael E. Brunner Dr. and Mrs. Alessandro de Alarcon Mr. Michael F. Epplen Mr. Charles R. Grone Mr. David Wiser Mrs. Arlene Bertellotti Mr. and Mrs. Stephen D. Bryen Mr. and Mrs. Jeffrey R. Decker Mr. and Mrs. William T. Fagin II Dr. Neera Gulati Mr. and Mrs. Michael R. Witte Mrs. Janet Betts Mr. and Mrs. Mark E. Buchheit Dr. William R. DeFoor and Ms. Karen Fahlgren Dr. D. Robert Haas Dr. and Mrs. Edward J. Wnek Mr. Mark S. Bever and Mr. and Mrs. Michael W. Burlingham Dr. Catherine A. DeFoor The Farmer Family Foundation Beth Joanna Habbert Memorial Fund Ms. Gin L. Wong Ms. Nancy J. Burns Ms. Jessica H. Byerly Mr. and Mrs. James K. Dempsey III Mr. and Mrs. Gregory M. Feary Mr. and Mrs. David W. Hammer Wood-Byer Foundation Mr. and Mrs. Paul Beyer Jr. Dr. Donita Bylski-Austrow Ms. Dawn M. Denno Mrs. Robin L. Felty Mr. and Mrs. David E. Hampton Dr. Linda L. Workman Dr. and Mrs. Jorge A. Bezerra Dr. Marc M. Cahay Mr. and Mrs. Jeffrey DeRossette Mr. and Mrs. David L. Fisher Mr. and Mrs. James N. Harjo Sr. Dr. and Mrs. Richard A. Yauss Mr. and Mrs. Douglas S. Bible Ms. Barbara Campbell Dr. Peter Dickie Mr. and Mrs. Marc D. Fisher Mr. and Mrs. John C. Hartman Marilyn and Thomas Zemboch Mr. and Mrs. Robert A. Bitter Mr. and Mrs. Robert A. Carpenter Mr. Richard Dobson Mr. and Mrs. Brian Florko Mr. and Mrs. Michael D. Hartman Mr. James Zenni Mr. and Mrs. Tom Booth Mr. and Mrs. Samuel M. Cassidy III Mr. and Mrs. Richard D. Dobson Mr. and Mrs. Jeremy D. Focht Mr. and Mrs. Steven R. Hartman Ms. Sharon E. Ziegler Mrs. Monica Borell Mr. and Mrs. Ryan K. Chambers Mrs. Clarissa C. Doggett Mr. and Mrs. Earl D. Folker The Hayden Foundation Mr. and Mrs. Ronald R. Borgman Mr. Weiguo Chen Mr. and Mrs. Ronald J. Dolan Mr. and Mrs. David E. Foxx Dr. Daniel Heffernan $500 – $999 Mr. and Mrs. Thomas W. Bosse Mr. and Mrs. Kyle M. Chirico Mr. and Mrs. James M. Dole Mr. Steven L. Frank Mr. and Mrs. Anthony E. Helton Ms. Ngqika Abdul-Khabir Mr. and Mrs. Charles Bost Mr. Kevin M. Clark Ms. Lisa Dorriere Mr. and Mrs. Ralph Freiberger Colonel and Mrs. Thomas Henwood Dr. Denise M. Adams and Mr. Ms. Mary A. Bowling Mr. and Mrs. Michael P. Cloughessy Mr. and Mrs. Donald J. Doyle Jr. Mr. Alan P. French Christopher S. Adams Mr. and Mrs. Gerald L. Heringer Ms. Catherine O. Bradford Mr. Timothy J. Collins Mr. and Mrs. Richard J. Driscoll Mr. and Mrs. Donald C. Fritz Mrs. Ruth Adams Mr. and Mrs. Christopher N. Herrell Dr. and Mrs. Kim Brady Mr. and Mrs. Fred Cooper Mr. and Mrs. Gary G. Drook Mr. and Mrs. Daniel J. Gahl Mr. and Mrs. James T. Aglamesis Mr. and Mrs. Gregory L. Herrin Mr. and Mrs. Joseph A. Brant Ms. Melinda S. Corcoran Mr. and Mrs. Dana M. DuBois Mr. and Mrs. Lawrence R. Gamblin Dr. and Mrs. Henry T. Akinbi Mr. and Mrs. Theodore F. Herschede Mr. Mark Brasington Mr. and Mrs. Gary G. Cox Mr. and Mrs. Christopher A. Dyer Mrs. Susanne E. Geier Mrs. Sharon L. Andersen Dr. Andrew D. Hershey and Mr. Stephen Breech Dr. and Mrs. Edward J. Crane Ms. Stephanie Ebken Mr. John B. Goering Dr. Gurjit Khurana Hershey Ms. Michelle L. Annis Mr. and Mrs. Jerome A. Brehm Mr. John Craynon Ms. Elli Edwards and Mrs. Dolores S. Goldfinger Mr. and Mrs. Jeffrey G. Hester Anonymous (2) Mr. John W. Brod Dr. and Mrs. Michael D. Crenshaw Mr. Michael Scarpa Mr. Jack Goldsmith Mr. Donald Hiler Mrs. Wilma D. Anthony Dr. and Mrs. Alan S. Brody Dr. Gail Croall and Mr. David T. Croall Mr. and Mrs. W. Charles Ehlers Ms. Kathleen Good Mr. John J. Hill

48 49 Mr. and Mrs. Thomas G. Hoel Mr. Kenneth Kemen Dr. and Mrs. Ronald S. Levin Mr. and Mrs. William G. McBrayer III Mr. Nicholas P. Miller and Mrs. Diana L. Nordling Mr. and Mrs. David D. Hoguet Mr. Michael R. Kemer Mr. and Mrs. Ozzie Levine Ms. Mara M. McClellan Ms. Hillery A. Banawitz Mr. and Mrs. Robert P. Nordloh Mr. and Mrs. Irving W. Horowitz Mr. Steven Kenat and Ms. Heidi B. Jark Mr. and Mrs. James I. Lewis Mr. Edward L. McClure Mrs. Arlene F. Mitchell Dr. and Mrs. Thomas R. Nymberg Mr. and Mrs. Terry L. House Mr. James R. Kimmel Mr. and Mrs. Michael Leyritz Mr. Scott McDermott and Mrs. Judy A. Moermond Mr. Michael F. O’Connor Mr. and Mrs. James R. Huesing Mr. and Mrs. Paul W. King Mr. and Mrs. Ralph W. Little Ms. Shannon Studebaker Mr. and Mrs. John A. Monroe Ms. Mandy O’Leary Ms. Elizabeth J. Hunt Ms. Angela Kinstler Mr. Mark Lloyd Mr. and Mrs. Robert E. McEwan Mr. Richard T. Morgan Mr. Michael E. Ollinger Dr. Lisa L. Hunter and Ms. Shawna K. Kirkendall Mr. and Mrs. John A. Lobono Mr. Sarah McGough Mr. and Mrs. Richard C. Morris Jr. Dr. Lauren R. Ostling Mr. Richard W. Smolak Mr. and Mrs. David A. Kitzmiller Mr. and Mrs. Leon H. Loewenstine Sr. Mr. and Mrs. Larry T. McGruder Mr. and Mrs. Mark Moskowitz Mr. and Mrs. James Overbey Mr. John M. Isidor and Mr. and Mrs. Robert M. Klare Mr. Terrence Loftus Mr. and Mrs. Thomas M. McKee Mrs. Marjorie Motch Mr. Richard A. Padgett Ms. Sandra P. Kaltman Mr. Barry S. Klein and Mr. and Mrs. Kevin L. Logemann Mr. and Mrs. Edward P. McNamara Mr. and Mrs. Michael S. Nelson Mr. James Page Ms. Janet Jacob Ms. Dawn M. Denno Mr. Joseph Lohre Meisel Family Foundation Inc. Mrs. Jenifer Neltner Dr. Shobana Pandian and Mr. and Mrs. Mark Jeanmougin Ms. Lori S. Klug Mr. and Mrs. John M. Lohrer Mr. and Mrs. Carl W. Mercurio Mr. and Mrs. Joseph B. Neville Dr. Joseph Eapen Dr. Clinton H. Joiner and Mr. and Mrs. Thomas B. Koenig Dr. Jason T. Long Dr. Arnold C. Merrow Mr. and Mrs. Jerry Newell Paroz Family Foundation Dr. Mary E. Frederickson Mrs. Christina S. Kohnen Mr. and Mrs. Kurt Louis Mr. and Mrs. Richard G. Meyer Mr. and Mrs. Andy Newton Dr. Peter Pathrose Ms. Diane B. Jokerst Mrs. Suzanne Kopcha Mr. and Mrs. Ted M. Lucien Dr. Linda J. Michaud Mr. and Mrs. Simon C. Nielsen III Mr. Mario Patino Mr. and Mrs. Leighton Jones Mr. Mark U. Krone Mr. and Mrs. James E. Lunsford Mr. and Mrs. Larry Middendorf Dr. Orly Ben-Yoav Nobel and Mr. and Mrs. David W. Peck Mr. and Mrs. Andrew J. Junga Ms. Tina M. Kroovand Mr. and Mrs. Christopher G. Lutz Mr. Alexander P. Miller Mr. Robert Nobel Mr. and Mrs. John E. Pepper Jr. Mr. Paul Justice Dr. and Mrs. Darcy A. Krueger Mr. Eric Mailloux Ms. Judith E. Miller Mr. and Mrs. Robert B. Noll Jr. Mrs. Dorothy H. Perlman Dr. and Mrs. Suhas G. Kallapur Mr. and Mrs. Joseph L. Kuhlman Dr. Janine C. Malone and Dr. Geraldine M. Kaminski Mr. and Mrs. John P. Kuhr Sr. Mr. Joseph A. Malone MAKING A DIFFERENCE Mr. and Mrs. Garrett A. Kamstra Mr. and Mrs. Samir Kulkarni Dr. and Mrs. Peter B. Manning Mrs. Olga D. Kanuschak Mr. and Mrs. Daniel Kuy Mr. and Mrs. Eric M. Markus Ms. Lisa Keegan Mr. and Mrs. Andrej P. Kyselica Dr. Lisa J. Martin and David and Nancy Wolf Ms. Lisa K. Keehan Dr. and Mrs. Stephen L. Lamendola Mr. Chad J. Martin David and Nancy Wolf have a theory about the secret gift, the Wolfs have funded an opportunity for doctors Mr. Thomas K. Keehan Mr. Matthew G. Lanier Mr. and Mrs. John R. Martindell of our success, and they want to share that with children from Israel to do just that. The David and Nancy Wolf Mrs. Barbara Keeling Mr. and Mrs. Brian Lawson Dr. and Mrs. Jack Matyas around the globe. “A special passion exists at Cincinnati Israel Exchange Training Program provides top medical Ms. Lisa A. Kellar Mr. and Mrs. Daniel W. LeBlond Dr. and Mrs. Todd A. Maugans Children’s,” David says. “Nancy and I have seen it in every students from Israel with the opportunity to spend time doctor, nurse and staff member. We want doctors and at Cincinnati Children’s learning from our world-class Mr. and Mrs. Jay Keller Mr. and Mrs. Guenter Lensges Mr. and Mrs. Douglas C. Maxwell researchers from across the world to experience that passion physicians and researchers, impacting an exponential Mr. Paul A. Kelly Mr. and Mrs. Lawrence A. Leser Mr. Tony Mazzone and carry it on to their patients.” Through a generous number of doctors and patients from across the world.

50 51 Mr. and Mrs. Scott Sheffer Mr. and Mrs. Charles H. Taylor Mr. and Mrs. Herbert B. Weiss Dr. Sally R. Shott and Mr. and Mrs. Michael L. Taylor Mr. and Mrs. Mark Wendling Mr. Andrew M. Shott Mr. Nicholas Teegarden Ms. Mary Sue Wentzel Mr. and Mrs. Christopher R. Simon Dr. and Mrs. Roger E. Teller Mr. Barton Weprin Ms. Melody L. Siska Dr. Nathan Timm and Mr. Thomas E. Wheat and Mr. Drew L. Smith Dr. Kimberly Daly Ms. Anne E. McGrath Dr. and Mrs. Hugh C. Smith Jr. Mr. J. Raphael Tincher Ms. Katrina White Dr. Teresa A. Smolarek Mr. James N. Trumble II Mr. Roger B. White and Mr. R. J. Solway Mr. and Mrs. William Tsacalis Mrs. Marsha K. Lee-White Mr. Robert D. Sommer Mr. and Mrs. Benjamin T. Tunney Mr. and Mrs. Steven M. Wilhelm Mr. J.D. Spahn Ms. Molly Vance Mr. and Mrs. Gregory K. Williams Mr. Randal Spear Mr. and Mrs. Eric Vanderschueren Ms. Tabitha Williamson Mr. and Mrs. Brian W. Pfeiffer Mr. and Mrs. Sean D. Rice Dr. and Mrs. Michael D. Scheiber Mr. Peter Spreen Ms. Sue M. Vanney Mr. Steven R. Wilson Dr. Jannel Phillips Dr. and Mrs. Ward R. Rice Mr. and Mrs. Steven C. Schlachter Dr. Mary A. Staat Mr. and Mrs. Drew Verdecchia Mr. and Mrs. Bradley Wittenbaum Mrs. Vivian Planck Mr. Kenneth Richardson Dr. Mary W. Schley Mr. and Mrs. Kenneth W. Stecher Dr. Marty O. Visscher Dr. Yan Xu Mr. and Mrs. Sanford H. Pliskin Ms. Terri A. Roberts Mr. and Mrs. Anthony J. Schmidt Steenberg Family Foundation Dr. Brian E. Volck and Mr. and Mrs. Gary Yarger Ms. Eveline A. Poe Mr. and Mrs. Stacey M. Robinson Mr. Robert C. Kanter and Mr. and Mrs. Bertram H. Steinhard Dr. Jill S. Huppert Mr. and Mrs. Thomas Young Mr. and Mrs. Barry S. Porter Mr. and Mrs. Jack Robke Dr. Rosemary E. Schmidt Mr. and Mrs. Jerry D. Stephenson Mr. and Mrs. Joseph P. Vonderhaar Mrs. Layel Zelazny Mr. Mark E. Potticary Mr. and Mrs. Robert T. Roeder Mr. and Mrs. Thomas D. Schmidt Ms. Janine Stockmeier Mr. and Mrs. Jeffery J. Waggoner Mr. and Mrs. Donald A. Zengel Mr. and Mrs. Randy Potts Mr. and Mrs. Lawrence C. Rohling Mr. John H. Schnehain Mrs. Caroline F. Sutphin Ms. Judith A. Walsh Mr. and Mrs. James T. Ziegler Mr. J. Dale Proffitt Dr. and Mrs. Marc E. Rothenberg Mr. Eugene Schneider Mrs. Jean W. Sutphin Mr. George W. Webb Ms. Maria Zigmunt Mr. Adam Puccini Mr. Ricardo Ruiz Mrs. Joan E. Schraml Mr. Richard Sutphin Mr. and Mrs. David A. Weiper Mr. and Mrs. John R. Zimmerly Mr. Christopher Puckett Mrs. Jennifer Ruschman Ms. Margie Scruggs Dr. Mary E. Sutton Mr. and Mrs. William W. Pugh Mr. and Mrs. Craig Russell Mr. and Mrs. Robert J. Searfoss Ms. Doreen A. Quinn Mr. and Mrs. Brian M. Russell Ms. Sylvia F. Sears MAKING A DIFFERENCE Mr. and Mrs. Arthur J. Raible Jr. Dr. Michael Rutter Mr. and Mrs. Marcus Sebens Mr. and Mrs. Robert B. Raines Mr. and Mrs. Robert P. Saalfeld Mr. Sai Shankarlingam and “Our family chose to help Cincinnati Children’s because it was a smart investment. They had the Mr. and Mrs. Daniel F. Rechtin Mr. and Mrs. R. Daniel Sadlier Mrs. Anitha T. Panchanathan infrastructure in place needed to make a meaningful impact on the disease. We knew our investment Mr. and Mrs. Gregory E. Reder Mr. and Mrs. Jason T. Saskowsky Mr. and Mrs. Manivakkam J. Shanker would yield results.” Karen Philip, The Buckeye Foundation

52 53 William Cooper Procter Society Ms. Anna M. Elsasser Mrs. Willa M. Garner Mr. and Mrs. John W. Hayden The William Cooper Procter Society recognizes and honors friends of Cincinnati Children’s who inform us that they have included Ms. Gladys R. Elsasser Ms. Alice M. Geier Dr. and Mrs. Richard B. Heyman the medical center in their will, estate plan or other deferred gift arrangement. Named in memory of Colonel Procter, whose Mr. and Mrs. Mark G. Essig Mrs. Susanne E. Geier Mr. and Mrs. Richard L. Hildbold visionary gift established our research endowment, this society acknowledges these generous individuals who have chosen to Mr. and Mrs. David Falk Dr. John A. Gennantonio and Mrs. Kathleen L. Hill leave a legacy to improve children’s lives for generations to come. Dr. and Mrs. Michael K. Farrell Dr. Margretta E. Gennantonio Mr. and Mrs. Roy D. Hockney Ms. Terri J. Feie Dr. and Mrs. Roger G. Giesel Mrs. Barbara Hoekenga Mr. and Mrs. John B. Fillion Ms. Gladys R. Glassmeyer Ms. Marion R. Holthaus Mr. Michael D. Finch Mrs. Dolores S. Goldfinger Mr. and Mrs. Wallace R. Holzman Jr. Dr. and Mrs. Ira A. Abrahamson Jr. Mrs. Beatrice Bluestein Mrs. Charlene F. Combs Michael and Suzette Fisher Mr. Wayne C. Gover Ms. Shawn Hooper Ms. Jean L. Abrahamson Mr. and Mrs. Donald R. Blum Mr. and Mrs. Michael A. Conner Mrs. Barbara J. Fitch Dr. and Mrs. Gregory A. Grabowski Mr. and Mrs. Terence L. Horan Dr. and Mrs. Richard I. Abrahamson Dr. Thomas and Dr. Barbara Boat Mrs. Lois A. Cooper Mr. and Mrs. Sheldon R. Flowers Mr. and Mrs. Gaylord R. Gross Mr. and Mrs. Jason Humphreys Dr. Ann L. Akeson Dr. Janet A. Borcherding Dr. Robin T. Cotton and Dr. and Mrs. Harold Fogelson Mr. Raymond J. Haarman Mr. Richard L. Hunt* Mr. and Mrs. Samuel M. Allen Mr. and Mrs. Elroy E. Bourgraf Sr. Ms. Cynthia M. Fitton Mr. and Mrs. Walter C. Frank Mr. and Mrs. Alfred P. Hallam Dr. and Mrs. Joe F. Inman Mr. Robert A. Anderle Mr. and Mrs. Harry L. Bradbury Dr. and Mrs. Alvin H. Crawford Mr. and Mrs. William A. Friedlander Mrs. Margaret H. Hamer Ms. Barbara A. Jackson Mr. James M. Anderson and Mr. and Mrs. Lawrence W. Bratburd Mrs. Geraldine Crawford Mr. Robert B. Friedman Mr. and Mrs. Scott J. Hamlin Dr. Richard L. Jackson and Reverend Marjorie C. Anderson Mrs. Mary E. Briggs Dr. and Mrs. Stephen R. Daniels Lillian M. Fritz Mrs. Marilyn H. Harra Dr. Judith A. Harmony Mr. and Mrs. Robert D.H. Anning Mrs. Lela C. Brown Mrs. Barbara R. DeGarmo Dr. and Mrs. William M. Fye Mr. and Mrs. Thomas P. Hatala Mrs. Betty K. Johnson Ms. Carole J. Arend Robert Rogan Burchenal Foundation Dr. and Mrs. Charles Deitschel Jr. Dr. and Mrs. Bruce J. Aronow Mr. Peter W. Bushelman Dr. Alexander M. Della Bella MAKING A DIFFERENCE Dr. and Mrs. Richard G. Azizkhan Mr. and Mrs. Michael S. Cambron Mrs. Barbara Dellerman Dr. Diane S. Babcock Mr. and Mrs. Lee A. Carter Dr. and Mrs. Thomas G. DeWitt Dr. Earladeen D. Badger Department of Surgical Services, Mr. and Mrs. William O. DeWitt Jr. Tom and Mary Ellen Cody Mrs. Elaine H. Baverman* Cincinnati Children’s Ms. Audrey J. Dick “Anything you can do to get involved with Cincinnati and education. The Codys’ gift will impact all three. Dr. and Mrs. Corning Benton Division of Pediatric Otolaryngology, Ms. Lynne Downs Children’s is a privilege,” says Tom Cody, chairman of In addition to supporting continuing education for the Mr. and Mrs. Ronald W. Beshear Cincinnati Children’s Ms. Jane R. Dummer the Cincinnati Children’s Board of Trustees. In addition institute’s pediatric cardiac specialists, it will also expand Dr. Francis M. Biro and Dr. Douglas F. Clapp Mr. and Mrs. Todd M. Duncan to his institutional leadership, Tom and his wife Mary the Ventricular Assist Device (VAD) Program. VADs are Ms. Nancy L. Bloemer Mr. and Mrs. James W. Cochran Ms. Donna S. Eby Ellen are passionate philanthropists who are leading mechanical pumps used to keep patients alive while they by example through their generous support of the Heart wait for heart transplants, and they are also being studied David D. Black* Mr. and Mrs. Thomas G. Cody Sr. Dr. and Mrs. Franklin J. Edge Institute. The institutes at Cincinnati Children’s are as a treatment to repair cardiac muscle damage, reducing Mr. and Mrs. Thomas C. Blinn Mr. Reed L. Coen Mrs. Joan T. Ehas grounded on three mainstays–clinical care, research the number of patients needing heart transplants.

54 55 Ms. Lyn M. Jones Dr. Harold K. Marder and Mr. and Mrs. Patrick O’Brien Ms. Arlene J. Sansone Ms. Michelle B. Starkey Drs. Brad W. Warner and Mrs. Mildred A. Jones Dr. Jewel D. Slesnick Mr. and Mrs. Richard H. Okenfuss Mr. and Mrs. Robert B. Sathe Dr. James F. Steiner Barbara B. Warner Ms. Margaret H. Jung Ms. Marie A. Marley Dr. Sonya G. Oppenheimer Ms. Donna L. Schiff Mrs. Mary S. Stern Dr. Richard B. Warriner III Dr. Mark A. Kahn Dr. and Mrs. James M. Marrs Mr. Maurice E. Oshry Dr. and Mrs. Robert C. Schiff Jr. Dr. and Mrs. Richard J. Stevenson Mr. and Mrs. Todd Washburn Mrs. Olga D. Kanuschak Dr. and Mrs. Lester W. Martin Mr. Bruce A. Pavlech Mrs. Nancy L. Schlemmer Mr. and Mrs. Charles N. Stix Mr. Dustin J. Waters Mrs. Molly E. Kaplan* Mr. Manuel D. Mayerson* Mr. and Mrs. Charles H. Pease Mr. and Mrs. Robert F. Schmidt Ms. Kathleen J. Stotler Mr. and Mrs. Barry S. Weinstein Mrs. Marie C. Katzenstein Mrs. Rhoda Mayerson Mr. and Mrs. Kroger Pettengill Mr. Robert C. Kanter and Dr. C. Frederic Strife and Mr. Harvey M. Weitkamp Dr. and Mrs. Emanuel Kauder Mr. and Mrs. Dale L. McGirr Dr. Steven M. Pilipovich Dr. Rosemary E. Schmidt Dr. Janet L. Strife Dr. and Mrs. Thomas R. Welch Mr. Aloysius F. Keller Mr. and Mrs. Michael S. McGraw Mr. and Mrs. Geoffrey Place Ms. C. Jean Schroer Dr. and Mrs. David M. Sullivan Mr. and Mrs. Robert Wert Dr. and Mrs. Thomas R. Kimball Dr. and Mrs. Robert L. McLaurin Mr. and Mrs. John J. Planes Jr. Dr.* and Mrs. William K. Schubert Mr. G. Richard Thomas Dr. Clark D. West Mr. Allen J. King Dr. J. Scott McMurray Mr. and Mrs. Robert B. Raines Mr. and Mrs. Phil F. Schultz Mr. James L. Thompson Mrs. Patricia P. Whitaker Ms. Patricia Kisker* Jeanette L. Meier Dr. and Mrs. Joseph L. Rauh Dr. William J. Scott Jr. Mr. and Mrs. Paul H. Tobias Dr. and Mrs. Jeffrey A. Whitsett Mrs. Margaret W. Kite Dr. and Mrs. C. Nelson Melampy Mr. and Mrs. Louis Rauh Kenneth and Lois Sears Dr. Joseph C. Todd Dr. and Mrs. J. Paul Willging Mr. and Mrs. Ronald A. Koetters Dr. Mary P. Melvin* Dr. and Mrs. Stephen M. Rauh Mr. and Mrs. David B. Sharrock Dr. and Mrs. Thomas U. Todd Dr. and Mrs. Gordon W. Womack Mrs. Gladys M. Kurtz Reverend and Mrs. Roger L. Meredith Dr. and Mrs. J. Mark Reed Dr. and Mrs. Curtis A. Sheldon Mr. Leonard C. Tolliver Jr. Mrs. Jean E. Wommack Dr. Beatrice C. Lampkin Dr. and Mrs. Richard A. Meyer Dr. and Mrs. David M. Rider Mrs. Kathleen A. Sherlock Dr. and Mrs. Randolph T. Travis Mrs. Joan R. Wood Dr. and Mrs. Robert J. Lerer Mrs. Frances M. Miller Reverend Mr. Luis O. Riva Saleta Mr. Andrew M. Shott and Mr. and Mrs. Ronald E. Vankalker Mr. and Mrs. Robert C. Woodiwiss Dr. and Mrs. James L. Lessard Mr. John N. Miller Mrs. Marjorie B. Robbins Dr. Sally R. Shott Dr. and Mrs. Jeffrey J. Wacksman Dr. and Mrs. Frank C. Woodside III Dr. Joseph E. Levinson and Ms. Judith E. Miller Dr. and Mrs. Jeffrey Robbins Ms. Miriam R. Siegel Ms. Saundra E. Walker Ms. Lynne T. Wu Dr. Sophia M. Levinson Dr. Anthony J. Mortelliti and Mr. and Mrs. Gerald J. Robinson Dr. and Mrs. Hugh C. Smith Jr. Mr. and Mrs. John P. Zanotti Dr. and Mrs. Philip K. Lichtenstein Dr. Gisella Mortelliti Mrs. Phyllis M. Romanow Mr. Thomas A. Long* and Mrs. Marjorie Motch Ms. Andrea T. Rosenthal Dr. Ann R. Gelke Carl J. Mueller* Mrs. Ruth F. Rosevear Dr. John R. Liu and Ms. Kari A. Jodal Ruth M. Mueller Dr. Robert R. Ross Dr. Jennifer M. Loggie Dr. and Mrs. Charles M. Myer III Mr. and Mrs. Snowden M. Rowe Mr. George B. Lott and Mrs. Gayle R. Nesselhuf Mr. and Mrs. Michael P. Russell Ms. Barbara N. Wurth Mr. and Mrs. Joel L. Newberg Estate of Lucile H. Ryan Mr. and Mrs. Ronald W. Lyons Mr. and Mrs. Hale Newman Dr. Frederick C. and Mr. and Mrs. Millard H. Mack Mr. Paul L. Niklas Mrs. Susan H. Ryckman

56 Estates and Trusts Corporations, Foundations and Other Nonprofits Throughout our history, Cincinnati Children’s has benefited from thoughtful friends who have provided for the future needs Businesses, foundations and nonprofit organizations–both large and small–partner with Cincinnati Children’s in our important of the medical center. With grateful appreciation, we honor the memory of these donors who provided a gift during the past work. Their generous support of our mission plays a vital role in advancing care for patients and families, while strengthening year through their estate plan. and enriching our community.

Rose M. Albrecht Trust Estate of Jackie Kasten Estate of Marie A. Reichel $1,000,000 + $100,000 – $249,999 Bill and Melinda Gates Foundation Doris M. Akeson Ida C. Kayser Trust Carolyn Rueppel The Convalescent Hospital for Children American Liver Foundation Histiocytosis Association of America William Belmont Backs and Dorothy M. M. Kersten Trust Estate of Lucile H. Ryan Cystic Fibrosis Foundation American Thoracic Society Hope on Wheels Hyundai Dealers Louise Nuxoll-Backs Trust Estate of Richard C. and Jean Kinstler Estate of Leroy E. Schilling (National Headquarters) Angels for Eosinophilic Josh Cares Mary S. Belville Trust Otto Luedeking Trust Charles W. Scott Trust Division of Emergency Medicine, Research Alliance The Sidney Kimmel Foundation Katherine E. Cooke Trust Estate of Donald J. Moeggenberg Michael M. Shoemaker Trust Cincinnati Children’s Children’s Digestive Health for Cancer Research The Edward and Edna Frances T. Marion H. Morrison Trust J. Frederick and Helen B. Vogel Trust Fondation Leducq Nutrition Foundation Kohl’s Department Stores Everlien Charitable Trust Dorothy T. Mueller Trust Estate of Mildred J. Walters March of Dimes Foundation The Children’s Heart Association Leukemia Research Foundation Estate of Joseph W. Heideman, Jr. Mandyam Dhati Narayan Trust Louise A. Williams Trust The Perinatal Institute Children’s Heart Foundation Lupus Foundation of America Inc. Juliet C. Muller Helmsworth Trust Betty H. Palmer Charitable Lead Trust Bernal R. Woodward Trust Toyota Motor North America Inc. Children’s Miracle Network Hospitals The H.B., E.W., and F.R. Luther Estate of Richard L. Hunt Cincinnati Center for Developmental Charitable Foundation, Fifth Third $500,000 – $999,999 Disorders Foundation Bank and Narley L. Haley, Co-Trustees American Heart Association Inc. The Cure Starts Now Foundation Macy’s Department Stores The Sontag Foundation Division of Pediatric and Adolescent Matching Gifts St. Baldrick’s Foundation Gynecology, Cincinnati Children’s Masimo Foundation

$250,000 – $499,999 Helen G., Henry F. & Louise Tuechter The Ohio National Foundation Autism Speaks Dornette Foundation, Fifth Third The Procter & Gamble Fund Bank, Trustee Burroughs Wellcome Fund Marge & Charles J. Schott Foundation Fifth Third Bank CancerFree KIDS Pediatric John A. Schroth Family Charitable Trust Cancer Research Food Allergy Initiative Speedway LLC Crohn’s & Colitis Foundation of America Fosdick & Hilmer Inc. The V Foundation for Cancer Research Orthopaedic Research & Foundation for Anesthesia Walmart Foundation Education Foundation Education and Research

59 $50,000 – $99,999 Robert Wood Johnson Foundation Bear Necessities Pediatric Macy’s Inc. Dairy Queen Corporation TriVersity Construction American Lung Association Markey Cancer Foundation Cancer Foundation Medtronic Foundation Dental Care Foundation, Truist (Headquarters) Max’s Blue Butterfly Children’s Cancer Research Fund Messer Construction Company Cincinnati Children’s Turner Construction Company Anonymous National Tuberous Sclerosis Association Cincinnati Bell Technology Solutions Muscular Dystrophy Association Inc. Endocrine Fellows Foundation Wound Healing Society Foundation Aplastic Anemia & MDS Ohio Cancer Research Associates Dikla Insurance Company Ltd. The PNC Financial Services Group Epic Systems Corporation $5,000 – $9,999 International Foundation The PNC Foundation Ethicon Endo-Surgery Inc. The Nelson Stark Company Gabrielle’s Angel Foundation AFLAC The Childhood Brain Society of Cardiovascular Fort Washington Investment Taft Stettinius & Hollister LLP for Cancer Research Tumor Foundation AHRA Education Foundation Anesthesiologists Foundation Advisors Inc. THP Limited Inc. GE Aviation Cystic Fibrosis Foundation The Archiable Electric Company Tourette Syndrome Association GBBN Architects Thrasher Research Fund The Gerber Foundation Therapeutics Inc. Bahl & Gaynor Investment Counsel Inc. UCB Inc. General Electric Evendale Employees’ Western & Southern Financial The Gorilla Glue Company Charles H. Dater Foundation Butler County Medical Center LLC Victory Wholesale Community Service Fund Group Masters Healthnetwork Foundation The Cambridge Charitable Foundation Fifth Third Asset Management Inc. General Electric Foundation Huron Consulting Group Inc. $25,000 – $49,999 $10,000 – $24,999 Chase Bank The Hartmann-Ryan Team Matching Gifts Interim HealthCare of Cincinnati Inc. at Cassidy Turley American College of Rheumatology American Academy of Allergy, Children’s Tumor Foundation HORAN International House of Pancakes Insuring The Children Research & Education Asthma & Immunology Circle K Midwest Howard Hughes Medical Institute The Frank J. Kloenne and Jacqueline Auction to Benefit Project SEARCH American Academy of Pediatrics International OCD Foundation Johnson Investment Counsel Inc. D. Kloenne Foundation Clover Hill Farm Inc. American Endowment Foundation Leukemia & Lymphoma Society The Columbus Foundation American Financial Group Inc. R.G. McGraw Insurance Agency Inc. Corporex Companies Inc. MAKING A DIFFERENCE American Society for Surgery National Hemophilia Foundation Cotswold Foundation of the Hand Al. Neyer Inc. CSL Behring LLC Anonymous Walmart/Sam’s Club NISH National Office Deloitte Carpet Cushions & Supplies Inc. When corporations and communities come together, Club family,” says regional manager David Gose. Operating Account DiaPharma Group Inc. Cincinnati Bell Inc. miracles can happen. Cincinnati-area Walmart and “Our customers and associates are parents, aunts and Ohio Casualty Foundation Duke Energy Foundation Cincinnati Music and Sam’s Club customers and employees rallied during the uncles, brothers and sisters and of course, grandparents. Ohio Credit Union League dunnhumbyUSA Wellness Coalition Children’s Miracle Network Hospitals’ Miracle Balloon When we see children who need medical care, we want Omnicare Inc. Foxx Construction LLC Campaign benefiting Cincinnati Children’s. This year’s to make a difference. The Miracle Balloon Campaign CinRon Marketing Group LLC The Peck Hannaford & Briggs Co. Frost Brown Todd LLC campaign was one of the most successful ever, more than provided an opportunity for our customers and associates Cisco Systems Inc. Plastic Surgery Foundation Genesys Telecommunications doubling last year’s contribution. to give whatever they could afford to children who need Citizens United for Research RCF Group Laboratories Inc. the level of care that Cincinnati Children’s provides, in Epilepsy “The children treated at Cincinnati Children’s hold Tackling TS Charity Give with Liberty Matching and they gave without hesitation.” Costco Wholesale-Springdale a special place in the hearts of the Walmart and Sam’s Gifts Program

60 61 GKN Aerospace Cincinnati Time Warner Cable Dell Inc. Palo Alto Networks Inc. Cafco Han’s White Tiger Tae Kwon Do Great Clips Inc. The Union Central Life Delta Community Credit Union The Procter & Gamble Company Anthony D. Castelli, Attorney at Law Harmony Staffing Services LLC The Highfield Foundation Insurance Company EMC Corporation Shareholder Services Department of Accounting, Healthcare Regional Marketing J.P. Morgan Chase & Co. United Way of Greater Cincinnati Five Guys Burger and Fries Ransohoff Inc. Cincinnati Children’s Hub Pen Company Inc. Katz, Teller, Brant & Hild Valvoline Instant Oil Change General Electric United Way Campaign Ruttle Design Group Inc. Department of Home Care Pharmacy, Human Arc Corporation Kicks for Kids WLWT Genzyme Corporation SGC Foundation Cincinnati Children’s IBM Employee Services Center Lundbeck Inc. Wright Brothers Inc. GR/AD Architects Smile Train Division of Infectious Diseases, Jack Dym Investment LTD. Cincinnati Children’s M&T Investment Group Graydon Head & Ritchey LLP The Success Group LTD. Johnstone Supply/Controls Center Inc. $2,500 – $4,999 Champion Window Mfg. & Supply Marriott Foundation For People United Group Services Inc. 3D Exhibits The Health Foundation Just Give With Disabilities of Greater Cincinnati Maxwell C. Weaver Foundation Cincinnati Wholesale Ice Cream Inc. Ace Hardware Foundation Kao Brands Company Marriott International Hispanics Avanzando Hispanics The Wilbert Foundation Cochlear Americas American College of Radiology Keating, Muething & Klekamp PLL Joanna McAfee Childhood Human Genetic Therapies Inc. Zanett Commercial Solutions Inc. Controlled Credit Corp. Avaya Inc. Kessler Foundation Cancer Foundation Huntington Bank Zeus Sports Inc. CREW Greater Cincinnati Baker Concrete Construction Key Foundation Matching Gifts Custom Glass & Glazing Inc. Miles That Matter Foundation J. II Fire Systems Inc. Kroger Company Bank of America $1,000 – $2,499 Cystic Fibrosis Foundation Olivia J. Murray Foundation Kenneth Wong Corporation LPK Bank of America Matching Gifts The 100 Times Foundation Corporation Pharmacy LLC MV Commercial Construction LLC KeyBank Martin & West PLLC Bayer Becker / Terracon W. Ron Adams P.S.C. Dinsmore & Shohl LLP Nativity The Pop Opera KLH Engineers Inc. McCarthy Strategic Solutions Beth Israel Deaconess Medical Center Akers Packaging Services Inc. Economy Linen & Towel Service PEDCO E & A Services Inc. Kolar Design Med Assets Brenco Inc. American Lung Association Every Child Succeeds Pension Corporation of America Lone Star Steakhouse & Saloon Building Blocks Foundation of the Midland States Med-El Corporation PNC Bank Findlow Filtration Inc. Lone Star Steakhouse-Middletown American Scaffolding Inc. Merrill Lynch Matching Gift Program Clever Crazes for Kids Fink Foundation Pomeroy Loth, Inc./IWS CBCE Arthritis Foundation Mid-American Junior Golf Tour RE/MAX Regional Services- FirstGroup America The Lubrizol Foundation BHDP Architecture Middletown Community Foundation cHc Manufacturing Inc. Gas America Charitable Foundation Alpharetta, GA Luckenbach Lines Inc. Chico’s FAS Inc. Bowling Green Pediatric Dental Group Mike-Sells Potato Chips Sigma Theta Tau International Honor The Patrick and Amanda Gavin Macy’s Foundation BP Fabric of America Fund New York Life Insurance Co-Cincinnati Society of Nursing Cintas Corporation Charitable Foundation Meijer Brooks Brothers Group Inc. Neyer Properties Inc. Society for Pediatric Dermatology CO-OP Financial Services The Greater Cincinnati Foundation Netscout Bruegger’s Enterprises Inc. Northrop Grumman Corporation Sodexo CTS Telecommunications Green Crest Golf Course Novartis International AG Buffalo Wild Wings Nutricia North America Strauss & Troy Curtis Inc. H & R Block Financial Advisors Inc. OMNOVA Solutions Foundation Butler Technology and Career Océ North America, Inc. Matching Thompson Hine LLP DeBra-Kuempel Carol and Ralph V. Haile Jr., ORACLE Gifts Program Development School U.S. Bank Foundation

62 63 Office Depot Regional Office Total Quality Logistics Carrigan and Grimm Inc. Illinois Tool Works Foundation Niscayah Inc. Standex Electronics Inc. Ohio Legislative Black Traction LLC Department of Home Health Care, Matching Gifts Northwestern Mutual-West Chester Steiner Electric Company Caucus Foundation Traincroft Inc. Cincinnati Children’s Information & General Services NxTech, Incorporated Stiles Associates Ohio Physical Therapy Association US Bank Chemed Foundation MBA Chapter OK Interiors Corporation Tactical Advantage Group LLC Omega Processing Solutions LLC Vorys, Sater, Seymour and Pease LLP Cheviot Savings Bank International Traders Inc. Dennis Ott Builders Inc. U.S. Bancorp Matching On Line Design Inc. Ashley Ward Inc. Chick-fil-A JPMorgan Chase Matching P L Marketing Inc. Gift Foundation Gifts Program Oticon Inc. Widmer’s Cleaners CINFAB, LLC The Pampered Chef United Cerebral Palsy of Greater JTM Provisions Co. Inc Phonak Corporation ComDoc Paragon Financial Group Cincinnati Inc. $500 – $999 Ben Kelhoffer Foundation Inc. Pitcher, Enders & Drohan CPA’s Inc. CTL Engineering Inc. Parkside Nursing and United Way of Greater Stark County AAkron Rule Corp. Planes Moving & Storage Inc. Custom Fabricators Inc. Kenwood Dealer Group Inc. Rehabilitation Center Vanguard Charitable Advanced Bionics Pratt Corrugated Holdings Inc. Customer Relationship Metrics LaRosa’s Pizzerias Passport Health Communications Inc. Endowment Program Advanced Health Media LLC Prestige Technical Services Inc. Cutting Edge Services Corporation LexisNexis Performance Honda Vitronic Promotional Group Alternative Design Pride Technologies Doner Financial Inc. LifeCenter Organ Donor Network Perry Interiors Inc. W E L Ventures Inc. American Cold Storage Systems Inc. Progressive Podiatry LLC Duke Energy Matching Gifts Program Lindhorst & Dreidame Company Pfizer Inc. Waltz Business Solutions American Cornhole LLC Radisson Hotel Cincinnati Riverfront Duke Energy-Zimmer Logistics and Procurement Services LLC Pinnacle Environmental Consultants Inc. Warren County Records Anonymous (2) Center & Archives Remke bigg’s Generation Station Market Precision Inc Reed Medical INC. Aptalis Pharma US Inc. Western & Southern Life August A. Rendigs, Jr. Foundation Duke Realty Corporation Maxor National Pharmacy Service Corp. REinvest Consultants Arts Rental Equipment Inc. Insurance Company Rite Aid Corporation Ernst & Young Foundation McLane Food Service Inc. #153 RespirTech Baule USA LLC WKRC-TV Sinai Hospital Express Employment Professionals Inc. Medco Employee Giving Campaign SALIX Baxter Healthcare Corporation Women’s Plastic Surgery Centre Scripps Financial Service Center Figure Weight Loss Miltenyi Biotec Inc. SEI-Cincinnati LLC Besse Medical Associates WRP Associates LLC See Kids Dream Food Lion MMG Corporate Communication Inc. Spina Bifida Association of Cincinnati R. P. Biederman Co. Inc. XL Insurance Group Semler Industries Inc. Gannett Foundation Matching Gifts M-Pact Corporation SpringHill Suites Boutique 280 YPO Forum X Sharefax Credit Union Inc. Genentech Inc. The Carter Nedley Foundation by Marriott-Waterstone Bow Automation Sheldon-Reder Gilead Sciences Inc. Bretagne, LLC Kentucky Account Suburban Real Estate Corporation Greystone Investments Management Brower Insurance Agency Incorporated Superior Honda Hahana Beach Tim Browne Memorial Inc. Teri Studios Handy Window Shade Inc. MAKING A DIFFERENCE The Bungie Foundation TGW International Inc. Healthlinx Executive Search Inc. “When we see children who need medical care, we think of their families and we want to work with CAI Insurance Agency Inc. Thunder11 Hill-Rom Holdings Inc. Cincinnati Children’s to make a difference.” David Gose, Walmart/Sam’s Club

64 65 Chairs and Fellowships The Beatrice C. Lampkin Chair The George Rieveschl, Jr., The Division of Pediatric We are grateful to the individuals, families, corporations and foundations that had the vision to establish permanent endowment of Pediatric Hematology/Oncology Chair in Research Surgery Research Chair accounts to benefit the children and families we serve. Their investment in the future of the medical center provides ongoing support The Joseph E. Levinson Chair The Jeff Robbins Chair The Katherine Stewart Waters for salaries, equipment and laboratory costs that are necessary to create new knowledge to advance and improve child health. of Pediatric Rheumatology The Thelma and Jack Rubinstein Chair of Experimental Hematology The Luther Foundation Research Chair Chair of Pediatric Developmental and Cancer Biology of Pediatric Pulmonary Medicine Disorders and Mental Retardation The Transplant Hepatology Chair The Lester W. Martin Chair The Richard Ruddy and Barbara The Carl Weihl Chair of General of Pediatric Surgery Wriston-Ruddy Chair of Pediatric and Community Pediatrics Chairs The Alvin H. Crawford Chair The Marjory J. Johnson Chair The Robert and Sarah McLaurin Chair Emergency Medicine Research The Clark D. West Chair The Division of Allergy of Pediatric Spine Surgery of Pediatric Hematology/Oncology of Pediatric Neurosurgery Research The Frederick C. Ryckman Chair of Pediatric Nephrology and Immunology Chair The Robert L. Creedon Chair The Marjory J. Johnson Chair The C. Nelson Melampy Chair of Pediatric Surgery The Louise M. Williams Chair The Richard and Geralyn Azizkhan of Pediatric Dentistry of Brain Tumor Translational Research of Pediatric Anesthesiology The Albert B. Sabin Chair of Pediatric Nephrology Chair of Pediatric Surgery The Division of Critical Care The Marjory J. Johnson Chair of The A. Graeme Mitchell Chair of Pediatric Infectious Diseases The William F. and Rebecca A. Balistreri Medicine Chair Vascular Tumor Translational Research Fellowships of Human Genetics The Schlemmer Family Chair Chair of Pediatric Hepatology The EMSC Chair of Pediatric The Neil D. Johnson Chair The William George Bauer Fellowship The M. Susan Moyer Chair of Pediatric of Pediatric Research The William S. Ball Chair ER Medicine of Radiology Informatics in Pediatric Hematology/Oncology Inflammatory Bowel Disease The Jacob G. Schmidlapp Chair of Radiology Research The Gunnar Esiason/Cincinnati Bell The Rob and Jessican Kahn Chair of The Mary Louise Burton Fellowship The Robert Myers and Mary of Pediatric Hematology/Oncology The Corning Benton Chair Chair of Life Sciences Research General and Community Pediatrics in Pediatric Gastroenterology Colgate Shoemaker Chair The William K. Schubert Chair of Radiology Education The James M. Ewell Chair The Samuel and Molly Kaplan Chair The Ruth Knittel Dietz Perinatal of Pediatric Endocrinology of Pediatric Research The Thomas Boat Chair of Pediatric Research of Pediatric Cardiology Research Institute Fellowship The Sonya Oppenheimer The Curtis Sheldon and Jeffrey of Pulmonary Medicine The David G. and Priscilla R. The Dorothy M.M. Kersten Chair The Katharine S. and Gerald J. Ficks Chair of Developmental Wacksman Chair of Pediatric Urology The Kevin E. Bove Chair Gamble Chair of Neonatology of Pediatric Gastroenterology Fellowship in Neonatology and Behavioral Pediatrics The Frederic and Carolyn Silverman of Pediatric Pathology The Division of Pediatric The Kindervelt Chair of Pediatric The Andrew Jergens Foundation The Division of Pathology Chair Chair of Pediatric Radiology The Hubert and Dorothy Campbell Gastroenterology Chair Pulmonary Biology Fellowship in Pediatric Endocrinology The Aaron W. Perlman Chair of The Charles H. Sloan Sr., Olive Louise Chair of Pediatric Pulmonology The Emma Margaret and Irving The Deb Kleisinger Chair The Junior Co-Operative Society Pediatric Rehabilitative Medicine Sloan, and Charles H. Sloan Jr. Chair The Lee Ault Carter Chair Goldman Chair of Pediatric of Novel Cancer Treatment Fellowship in Pediatric Diabetes The B.K. Rachford Chair of Pediatrics of General Pediatric Research of Pediatric Ethics Ophthalmology The Othilda Krug Chair The Junior Co-Operative The Louise W. and Joseph L. Rauh The StarShine Chair The Robin T. Cotton Research Chair The David N. Glass Chair of Child Psychiatry Society Fellowship in Pediatric Chair of Adolescent Medicine The Janet L. Strife Chair of of Pediatric Otolaryngology of Pediatric Rheumatology The Beatrice C. Lampkin Chair Infectious Diseases The Pauline and Lawson Reed Chair Radiology Quality and Safety The Alvin H. Crawford Chair The Carolyn Hamlin Chair of Cancer Biology The Ida C. Kayser Fellowship of Pediatric Infectious Diseases The Ralph J. Stolle Chair of Pediatric Orthopaedic Surgery of Otology Research in Pediatric Pulmonology of Pediatric Immunology

66 67 The Edward L. Pratt Fellowship The Reginald C. Tsang Fellowship in The Frank C. Woodside and Mr. Joshua C. Mack Timothy Browne Andrew J. Hagen in Pediatric Medicine and Nutrition Neonatology and Pulmonary Biology Dinsmore & Shohl Fellowship Kurtis Martin Raymond Buse III Christopher Harmon The Edward F. Scully Fellowship The Josef F. Warkany Fellowship in Epidemiology and Biostatistics Dr. and Mrs. Robert L. McLaurin Paul Carroll Kaylynn M. Hartman in Pediatric Endocrinology in Human Genetics Mr. Nick Moloney Dalton Chandler Joyce Heiman Mr. and Mrs. Jeffrey Northern Arun Chatterjee Zachary Heringer Ms. Priscilla Peyton Manuel Chavez Sr. Mary Hess Tribute Gifts Ms. Cameron Rawlings Steven A. Cirino II Mr. Anthony G. Hoel When donors make a gift in honor or memory of a loved one, our patients benefit from their generosity. We thank the families Dr. Pramod P. Reddy and Jennifer K. Clanton Kyle T. House and friends of the following individuals, who have had $500 or more donated in their name. Dr. Usha P. Reddy Phyllis Clyde Anabelle Huff Mr. Seth Rogers Bruce W. Cochran Alice Humbert Ms. Lynn W. Roy Sophia Cordier Elizabeth M. Igel In Honor Of Dr. Mitchell B. Cohen and Ms. Julien R. Guttman Brayden Schindler Joyce W. Coykendall Gregg Jacob Dr. and Mrs. Richard G. Azizkhan Dr. Morissa Cohen Dr. Nancy Hagerman Mrs. Catherine A. Schneider Hunter A. Creech Judith Johnson Mr. Lynwood L. Battle Jr. Ms. Maya Collins Ms. Sylvia Heiby Ms. Sara Shinn Mary Christine Daush Richard E. Kaeser Jamie Benassi Mr. Louis Costello Bailey A. Hemingway Mr. Reese Stuart Mrs. Shirley I. Davies Jenna Kamphaus Mr. Jake Bertellotti Dr. and Mrs. Kerry R. Crone Ms. Casey Hilmer Grace Tapp Rowan Dinn Joseph Kanuschak Mr. Pierce J. Blalock Carter John Davis Mr. Jacob T. Hoffman Dr. Ann Weichert Dr. Harold Downing John B. Kara Cameron I. Bordainick Colin Davis Ms. Kai N. Hollingsworth Dr. Brenda Wong Amanda M. Drake Ben Kelhoffer Mr. Matthew K. Bormet Mr. Shane P. DiGiovanna Mrs. Kristin Horsburgh Patricia Droppelman-Helton Hayes R. Kelley In Memory Of Mr. and Mrs. Elroy E. Bourgraf Sr. Tanner Dole Mr. Frank Wray and Erik Anderson Emily Dubois Richard C. Kinstler Mr. and Mrs. William C. Bredenfoerder Nicholas Dworjanyn Ms. Kathleen M. Kool-Wray Rebecca Archambeault Deborah L. Folker Matthew Korfhagen Nathaniel Brown Master Manish Eapen Ms. Katherine Koslovsky Regan Leigh Arnold Ayelet Y. Galena Wright Lanier Curtis G. Buerkett Mr. Ryan Elliot Dr. Helen Kranbuhl Henrietta F. Belmont Julia Gallino Jenna C. Laumer Master Michael Buerkett Ms. Elsa Fagin Mr. and Mrs. Venu G. Krishnamoorthy Michael Blessinger Clifton Kippy Gideon Andrew Lee Brady Campbell Ms. Marie Fern Mr. Jonathan J. Calderas and Lora Bodley Judith E. Gilliam Michael Little Dr. and Mrs. Daniel I. Choo Mr. Michael A. Fisher Dr. Corinne Lehmann Norbert Borgman Caroline Goebel Thomas A. Long Jonah Chuang Dr. David N. Franz Ms. Kathryn Leikhim Natalie Bost Kim Goebel Eleanor S. Lortz Mr. and Mrs. Thomas G. Cody Sr. Ms. Ava M. Gallino Dr. and Mrs. Marc A. Levitt Emily M. Brehm Joseph M. Gruber Patricia E. Macke Ms. Ashley Gavin Ms. Lauren Lloyd Gerardo (Jerry) Brindisi Florence Guttman Manuel D. Mayerson

68 69 Auxiliaries Junior Co-Operative Society President: Marjorie Gilsdorf United by a common interest in supporting the medical Gift: $482,832 center, Cincinnati Children’s auxiliaries have been essential to our success. If you would like more information about Established in 1910, the Junior Co-Operative Society our auxiliaries, or if you wish to join in their important operates and staffs the Gift Shops at Cincinnati Children’s work, please call 513-636-6080. Burnet and Liberty campuses. The Gift Shops are filled with a wonderful selection of toys, games, cards and books to lift the spirits of hospitalized children. All proceeds from the Gift Shops are donated to the medical center. Kindervelt Their dedicated volunteers live by their motto, “the more City President: Buffie Rixey you shop, the more we give.” Gift: $575,550

Our largest fundraising auxiliary, Kindervelt is widely Association of VolunteerS President: Jeane Elliott Shelia McCuddy Dr. Jack H. Rubinstein Joe Stima recognized as one of Greater Cincinnati’s outstanding Gift: $60,300 Sophie Meinhardt Michael Salt Abby Lyn Streszoff volunteer organizations. With nearly 1,000 members Patrick & Drew Meisenheimer Mitchell W. Sayre Robert Taylor Jr. in groups around the region, linked by a citywide board The Association of Volunteers has supported of trustees, Kindervelt truly lives its mission to “have the Convalescent Hospital for Children, an affiliate Tony R. Merk Robert F. Schapker Marjorie Timko fun while raising funds” for the patients and families of Cincinnati Children’s, for more than 40 years. William J. Meyer Francis J. Scharon Michael C. Torbeck of Cincinnati Children’s. In its more than 40-year history, To raise funds for the Convalescent Hospital, the Kyle Miller Holly Schmitz Samuel George Towne the women of Kindervelt have contributed over $15 million association sponsors the Cincinnati Art & Antiques Mary Susan Moyer Jonathan P. Schmitz Faith Venerable to the medical center. Festival. This four-day antique show, held each October, Ms. Janie Newton Dr. William K. Schubert Mason Ward is one of the largest and finest in the country. Kurt A. Ostling Paul D. Seiter Michael T. Washburn The Cooperative Society Norman Oxley Luke Seitz Lillian Wesner President: Nancy Sorg Funny Companie Clowns Gift: $761,600 Dr. Aaron W. Perlman George Shelby Molly West President: Donald Bachmann Gift: $13,160 Crystal G. Phillips Kathleen A. Sinkula Ronald West Our first auxiliary, the Cooperative Society has served Ian Pierce Sophia Jane Smallwood William Whitsett Cincinnati Children’s for more than 125 years. In addition Since 1983, the Funny Companie Clowns have been Bhama Rajaram Kortney Snyder Ryan Wilson to financial contributions, members of the Cooperative delighting children and adults throughout the community, Society also give generously of their time. Members volunteer while raising money for Cincinnati Children’s. The 25- Puli Pradip Reddy Russell Dale Stephenson Sarah E. Zoz for the Division of Child Life and Recreational Therapy, member volunteer auxiliary performs at holiday parties, the Mayerson Center for Safe and Healthy Children and company picnics, birthday parties and festivals, and has the sewing room. raised nearly $200,000 for the medical center.

70 71 Special Events and Community Organizations $2,500 – $4,999 B2B Halloween Bash- Kiwanis Club of Kenwood-Silverton- Special events bring people together to benefit our young patients, while building awareness of the medical center and children’s American Board of Internal Medicine Families Against Brain Injury Madeira Golf Outing health issues. Cincinnati Children’s thanks each and every volunteer and supporter who gave time, talent and resources for an Brenco Golf Outing Chipping In for Children Happy Hour Leis for Sheriff Committee event that benefited the medical center. Those events that raised $500 or more are listed here. Chippin’ in for Children CJCC Volleyball Tournament A Night In For Neuroblastoma SGC Foundation Golf Outing Cincinnati Friends of Charity Olde Sawmill Elementary Torch Relay Cincinnati Marathon, Inc. Our Lady of Lourdes School Toys for Nicholas Cincy Kids 4 Kids Primrose School of West Chester $500,000 + Katie Linz Foundation Becca’s 2nd Annual Legendary Turpin Parents Soccer Club John R. Estep Charity Golf Outing R.C. Hinsdale School Cincinnati Walks for Kids The Plaid Open Run for the Cure Xavier University Charity Golf Outing Families Against Brain Injury Rocks Football Team 7th and 8th Celestial Ball Sample, Savor and Support Liam Nolen Bradley Memorial Xavier University Dance Marathon Abby Glaser’s Family Talent Grade Car Wash Tennis Masters Series Fairlawn Local School Show Fundraiser Ronald McDonald House Charities $250,000 – $499,999 $1,000 – $2,499 of Greater Cincinnati Warrior Run: The Race For Life Ellen B. Ganson Memorial Foundation Green Crest Christmas Walk An Evening to Honor Milt Kantor Acoustic Night at Scotty’s Kendall’s Second Annual EB Walk/Run Han’s White Tiger Tae Kwon Do Ross-Butler Tech DECA $10,000 – $24,999 All Saints School Powder Puff Football Game $100,000 – $249,999 Kilgore Elementary Dance-a-thon Break-a-Thon Champions Fore Cincinnati Angels of Mercy the SaNyiah Saint Ignatius of Loyola Angels for Eosinophilic Research Kolping Seth Stevens Memorial Immaculate Heart of Mary Children’s Golf Outing Rose Lynn Memorial 7:30pm Music Group Golf Tournament Soccer Tournament Kenwood-Silverton-Madeira Funny Companie Clowns The Basement Band Paul Seiter Annual Memorial Fundraiser Ruth Lyons Children’s Fund Olivia J. Murray Second Kiwanis Golf Outing Hearts are Trump Euchre Tournament Annual Golf Outing $50,000 – $99,999 LEGO KidsFest Nativity The Pop Opera Annual Golf Outing Benefiting Neurosurgery Chiari Fundraiser Operation Beard for Bucks! MAKING A DIFFERENCE the Center for Infants and Children StarShine Hospice Cornhole St. Ursula Academy with Special Needs Charity Classic Orange & White Football Game Memorial Cancer Research Golf Outing Tri State Society of An Evening Honoring Milt Kantor Simon’s Fund Passport to Forever Healthcare Engineers, Inc. The Spirit Of Cincinnatus Milt Kantor is a businessman, a husband, a father, life and his generosity during an event that benefited StarShine Hospice Golf Classic Win a Wine Cellar Max Richard Thornsbury a grandfather and a friend to many. As an avid the Cancer and Blood Diseases Institute at Cincinnati philanthropist for most of his life, Milt has called upon Children’s. Guests included Bobby Knight, Cris $25,000 – $49,999 $5,000 – $9,999 Foundation-CDH Research many of his friends in the world of sports to share their Collinsworth, “Big O” Oscar Robertson, Dolph Schayes, Bluegrass for Babies 2012 Auto Expo Team Jenna time and resources for causes that are close to his heart. Bob Huggins and others who were thrilled to honor Milt Children’s Charitable Care Golf Outing Abby’s Run for the Heart Walk for EB while supporting the health and healing that Cincinnati Cincinnati Golfers for Charity For his 85th birthday, Milt’s family gathered some of those Association of Philippine Physicians Children’s provides for kids around the world. of Greater Cincinnati sports legends, and 500 other friends, to celebrate his

72 73 Shred Day-Souders Financial Group Greek Philoptochos Society Riverside Athletic Boosters Catholic Kolping Society of Cincinnati Ethicon Endo-Surgery Inc. Indy Racing League Spooky Film Festival Hoops for the Cure Rockdale Temple Religious School Department of Audiology, Felix Leshey Foundation Jimmy’s Limousine Service StarShine Plant and Flower Sale International Society for Research Saint Cecilia School Fundraiser Cincinnati Children’s First Christian Church Kai’s Love Hats Sycamore Community School District in Human Milk & Lactation Saint Ignatius of Loyola Cengage Learning First Watch Restaurants Inc. Ms. Hadia Kahn Sycamore High School Student Lakota West High School-School Saint Margaret York Parish Cincinnati Carvers Guild Mr. Daigle Fisher KIDSovercancer Foundation Council Event-Mr. Sycamore Government Association St. Romain Dance Academy Cincinnati Precision Instruments Inc. Mr. and Mrs. Jeremy D. Focht Kindergarden School Ben Kelhoffer Golf Outing South Central Ohio Minority Cincy Kids 4 Kids Mr. Grant Forster La Salle High School $500 – $999 Madeira City School District Supplier Development Council Cintas Corporation Mrs. Theresa L. Labbe Wise Bethel International Freestore Foodbank Shirley Mann Elementary School Amanda Thomson Piano Recital Cisco Systems, Inc. United Methodist Church Frisch’s Restaurants Mr. and Mrs. Rodney Ladrigan Sucker Sale “Ella’s Elves” Warren County Records Center Clark Montessori School Florence Lodge 33 From the Heart Church Lakota Plains Junior School Music Therapy Donation & Archives Bake Sale Foundation, Inc. Fraternal Order of Eagles Ministries of Cincinnati The LaRosa Family from Thomas Wright Lemier Westboro Friends Church Coca-Cola Refreshments Germania Society GE Aviation Dr. Ernest H. Lawhorn and Nu Chapter Omega Woodland Elementary Walk-a-Thon Mr. and Mrs. Thomas G. Cody Sr. Dr. Susan R. Lawhorn Gorilla Glue 1/2 Day Vacation Raffle Ms. Joanne Geiger Parkway Products Annual Golf Outing Coldwell Banker West Shell Mr. and Mrs. David Gilday Ms. Latisha Lewis Commonwealth Financial Network Mr. and Mrs. Olivier R. Gillier Dr. Anne Lucky Gifts-in-Kind Companions in Courage Foundation Girl Scout Daisy Troop #43840 Luxottica Retail Compass Group Girl Scout Troop #41725 Mann Elementary School We thank the following individuals, corporations and organizations that helped ease the stress of our patients and families with Coney Island their donations of toys, services and other non-cash gifts, valued at $500 or more. Girl Scout Troop #42599 The Marvin Lewis Community Fund Ms. Deanna Cox Mr. Gavin Goeser Mason Intermediate School Ms. Gail Cox Greater Cincinnati Relocation Ms. Virginia J. McDowell Ms. April Dalton Council (GCRC) Messer Construction Company Adopt-a-Book- Ms. Hanna Barlow Boy Scouts Pack 742 Ms. Barbara Decker GWRRA Chapter OhX2 Miami University Hannah and Alex Laman Mr. and Mrs. Arnold R. Barnett Brent James and the Contraband Mr. and Mrs. Jason Dickman Mr. Justin Hall Miami University Residence Amazon.com Bennett’s Beavers Ms. Tammy Brinegar The Dragonfly Foundation Hamilton County Sheriff’s Department Hall Association American Book Company Mr. and Mrs. Chad Blanchard Mr. and Mrs. Vasiliki Brunson Drawing Dreams Foundation Jeffrey Thomas Hayden Foundation Ms. Abby Murphy Mrs. Frank Anastasia Blue Ash Airport Days Mr. Daniel P. Bueche dunnhumbyUSA Mrs. Pat Hueslman Music to Heal APKE Premium Cleaning Bob Roncker’s Running Spot Bunnies By The Bay Mrs. Betty Dzeich Mr. and Mrs. Gary Huysse Nativity The Pop Opera Mr. and Mrs. Chris C. Ayers Books for Cure-Natasha Saputra Mr. Kevin Burton Elisha Lodge #106 IKEA West Chester Mr. Michael Nesi Ms. April Baker and Megha Battina Mr. and Mrs. Thomas M. Carroll Mr. and Mrs. David Ellis Indian Hill Newport Aquarium

74 75 Newport Independent School- Response Marketing Inc. Terrace Park Elementary Newport Intermediate School Roads, Rivers and Trails Mr. R. Jeffrey Thomas The Ohio State University College Dr. and Mrs. Jeffrey Robbins Mr. Richard Thomas of Veterinary Medicine The Alicia Rose “Victorious” Foundation Ms. Tari Torbeck Otis Spunkmeyer Inc. Mr. and Mrs. Jeff Rosenlieb Total Quality Logistics Ms. Catherine A. O’Toole Saint Susanna School Toyota Motor Sales, USA, Inc. Nina and Edward Paul Sans Souci Sorority Toys for Nicholas P.F. Chang’s China Bistro Scarlet Oaks Tri State Paranormal Pepsi Beverages Company The Friends of The School for of Northern Kentucky FINANCIAL REPORT PetSmart Creative & Performing Arts Ms. Missy Tripp Fiscal year 2012: July 1, 2011–June 30, 2012 Phillip A. Sharp Middle School Ms. Shannon Scott University of Cincinnati The PNC Financial Services Group Seven Hills Church University of Cincinnati-Public Safety Procter & Gamble Dr. and Mrs. Peter Y. Sheng Ursuline Academy (Dollars in Thousands) Q Laboratories Inc. Skyline Chili of Middletown Ms. Amy Vaughan Readers Hideaway Sodexo Walmart Foundation Operating Revenues and Expenses fy 2012 fy 2011 Pete Delois Recreations Outlet Mr. and Mrs. Joel Staffilino Warren County Records Mr. and Mrs. Eugene K. Reis Ms. Lynova Stamper Center & Archives Operating Net Hospital Patient Services Revenue $1,286,492 $1,144,142 Mr. and Mrs. Justin D. Reno Ms. Kimetra Stone Ms. Carol Wobser revenues Professional Services Revenue 252,401 229,749 Republic Capital Truck and Trailer Sale Ms. Tatiana M. Yewisiak Stonz Research Grants 149,858 153,914 Other Operating Revenue 162,987 165,603 * Deceased Total Operating Revenues 1,851,738 1,693,408

Operating Salaries and Benefits 1,072,522 1,033,823 expenses Services, Supplies and Other 514,968 479,392 Depreciation 119,574 110,716 Interest 15,926 16,104 Total Operating Expenses 1,722,990 1,640,035 As a nonprofit hospital and research center, we are grateful for all gifts made to Cincinnati Children’s. Unless otherwise noted, this report Available to Reinvest in the Mission $128,748 $53,373 lists all donors who gave $500 or more in fiscal year 2012 (July 1, 2011 through June 30, 2012). We have made every effort to be accurate and complete with this listing. Should you find an error or omission, please call the Department of Development at 513-636-6347.

76 77 (Dollars in Thousands)

Statistical Condensed Balance Sheet fy 2012 fy 2011 Highlights fy 2012 fy 2011 fy 2010 fy 2009 fy 2008

Assets Cash and Equivalents $169,667 $97,451 Patients Admissions (includes short stay) 30,579 30,951 32,981 31,217 27,392 Marketable Securities 258,903 227,642 Average Length of Stay (days) 4.7 4.4 4.1 4.4 4.5 Patient Accounts Receivable, Net of Allowances for Uncollectible Amounts 214,355 204,081 Emergency Department Visits 124,274 121,875 125,130 114,985 93,456 Other Current Assets 126,599 122,522 Patient Encounters 1,144,858 1,087,260 1,078,798 1,003,079 925,944 Current Assets 769,524 651,696

Property and Equipment, Net of Accumulated Depreciation 840,978 851,701 Funds Held in Trust 3,678 4,620 Outpatient Primary 65,347 65,446 65,915 60,243 61,788 Other Long-term Assets 81,324 74,261 visits Specialty 832,317 797,280 793,814 735,926 693,636 Interest in Net Assets of Supporting Organizations 937,327 886,162 Test Referral Center 65,247 29,868 28,374 29,635 31,941 Total Assets $2,632,831 $2,468,440

Liabilities Liabilities and Accounts Payable and Accrued Expenses $227,089 $188,643 Surgical Inpatient 6,365 6,141 5,667 5,667 6,323 net assets Current Portion of Long-term Debt 20,365 19,432 procedures Outpatient 27,094 26,168 25,492 24,669 22,845 Current Liabilities 247,454 208,075 Surgical Hours 44,240 42,874 40,825 39,462 43,325

Long-term Debt 467,223 481,471 Other Long-term Liabilities 441,819 245,039

Total Liabilities 1,156,496 934,585 People Active Medical Staff 1,572 1,516 1,498 1,442 1,292 Total Employees 12,932 12,654 12,368 11,666 10,680

Full-time Equivalents 10,976 10,781 10,455 9,871 9,104 Net Assets Unrestricted Net Assets 397,514 526,991 Temporarily Restricted Net Assets 156,702 135,943 Permanently Restricted Net Assets 922,119 870,921 Total Net Assets 1,476,335 1,533,855

Total Liabilities and Net Assets $2,632,831 $2,468,440

78 79 OUR LEADERS (Lists reflect leadership as of June 30, 2012)

Officers of the Board Board of Trustees

Thomas G. Cody, Esq. Sharry Addison Pamela Terp Chairman Robert D. H. Anning Felicia Williams Michael Fisher Carol Armstrong Craig Young President and Chief Executive Officer Richard G. Azizkhan, MD Trustees Ex Officio Vicki L. Davies Lynwood Battle Rt. Reverend Thomas Breidenthal Treasurer Michael S. Cambron The Episcopal Diocese of Southern Ohio Elizabeth A. Stautberg, Esq. Willie F. Carden Jr. Kay Fricke Secretary Lee A. Carter Family Advisory Council Thomas G. Cody, Esq. Katharine DeWitt Jr. Auxiliaries Nancy Krieger-Eddy, PhD Nancy Sorg Michael Fisher President, Cooperative Society Vallie Geier Marjorie Gilsdorf Louis D. George President, Junior Co-Operative Society Michael Hirschfeld, Esq. Buffie Rixey Joyce J. Keeshin President, Kindervelt M. Denise Kuprionis, Esq. Trustees Emeriti Peggy Mathile Ralph Burchenal Jane Portman Barbara Fitch John Steinman Kroger Pettengill Arnold W. Strauss, MD

80 ILLUMINATING DISCOVERIES

Production credits TABLE OF CONTENTS Affiliates Performance Leadership Team

Building a Research Legacy 1956–2012 on back cover 1883–1955 on FRONT cover Improving Child Health ILLUMINATING DISCOVERIES

Production credits TABLE OF CONTENTS Affiliates Performance Leadership Team

2012 ANNUAL REPORT