Summer, 1982 MINNESOTA MEDICAL FOUNDATION

Board of Trustees: Anthony Bechik. University of Minnesota Medical Contents: President; John Coleman. M.D., Vice Schools: Lyle A. French. M.D., Vice Class of 1982 President; Eivind 0. Hoff, Treasurer; President of Health Sciences; N. L. Gault. DonaldS. Asp. M.D.; Reuben Berman, M.D .. Dean, University of Minnesota 10 Class of 1932 M.D., Arley R. Bjella, Conley Brooks, Medical School. Minneapolis; Paul C. 13 Reunion '82 David M. Brown. M.D., H. Mead Cavert, Royce, M.D., Dean, University of 16 Focus on Basic Science: Department M.D., Litton E.S. Field, Lyle A. French. Minnesota-Duluth School of Medicine. of Pharmacology M.D., N. L. Gault. M.D., Eugene Publishing Information: The University 21 On the Campus Gedgaudas. M.D .. Stanley M. Goldberg, of Minnesota Medical Bulletin is M.D., Norman E. Groth, Terrance Hanold, published quarterly by the Minnesota 24 Honors Arnold Kremen. M.D., James LaFave, Medical Foundation in behalf of the 29 Medical Foundation M.D., Eva Jane Larson, M.D . Roger University of Minnesota Medical Schools 30 Focus on Alumni: Dr. Charles Larson. C. Peter Magrath. Dwight L. (Minneapolis and Duluth). Minnesota Sheppard Martin. M.D .. Stephen L. Maxwell, Medical Alumni Society, and the George McClintock, Rudolph W. Miller, Minnesota Medical Foundation. 33 Alumni Notes Wenda Moore. Donn Mosser. M.D., Paul Statements and opinions published 34 In Memoriam G. Quie, M.D .. Jerry E. Robertson, Paul herein are exclusively those of the Be sure to read inside back cover for C. Royce. M.D., Edward L. Segal, M.D., authors themselves. news of the 1982 Alumni Directory. Nadine Smith. M.D., Vernon D. E. Smith. There is no subscription fee. No M.D .. William G. Stocks, Robert H. advertising is accepted. Publication is Tucker. H. E. Westmoreland. C. Paul made possible by contributions to the Winchell. M.D. Minnesota Medical Foundation. Staff: Eivind 0. Hoff, Executive Director; Publication Office: Minnesota Medical Donald A. Engel, Thomas Patterson, Foundation, 535 Diehl Hall. University of Scott D. Lothrop, Bruce P. Anderson. Minnesota. Minneapolis. Minnesota Development; Kathy Broderick. Kay 55455 Phone: (612) 373-8023. Editor: Martha Roth Geoffrey. Programs. Change of Address: Please enclose old Photos: Biomedical Graphic Minnesota Medical Alumni Society: and new address and mail to: The Communications; Steve Heasley; Jim DonaldS. Asp. M.D., President; Jan T. Minnesota Medical Foundation, 535 Boulger; Tom Foley; Minneapolis Star & Adams. M.D .. Vice-president: Richard A. Diehl Hall. University of Minnesota, Tribune; St. Paul Dispatch-Pioneer Carlson. M.D .. Secretary-Treasurer. Minneapolis, Minnesota 55455. Press.

Letter to the Editor

Dear Editor. Among the teachers that I remember ambiguous status as a medical student, from my days as a student at the Uni­ he treated me as a colleague. From his versity of Minnesota Medical SchooL example I learned humility, kindness. Maurice Visscher. about whom you the excitement of scientific research. wrote so well in your Spring, 1982. and the satisfaction of investigative issue. was certainly one of that rare rigor. Whatever success I have had breed: an inspiring scientist, a devoted since then I owe in good part to a few humanist. and an understanding man. outstanding teachers. and Maurice Viss­ In 1947. I was fortunate enough to be cher was a giant among them. accepted as a research assistant by Dr. James M.A. Weiss. M.D., M.P.H .. Visscher. to work on a project on the FACP. FRCPsych genesis of pulmonary edema following Professor and Chairman. vagotomy. . . . Despite my somewhat Department of Psychiatry University of Missouri-Columbia Class of 1982 On the brilliant afternoon of June 4, before a cheering, clapping audience of relatives and friends in Northrop Au­ ditorium, 271 young men and women accepted the hood of a Doctor of Medi­ cine from the deans of the University of Minnesota Medical School. Dean N. L. Gault welcomed the graduates, the audience, the faculty, Prior Lake; Karen M. Gosen. Little Falls; Park; Scott J. O'Connor. Duluth: and and introduced the Class of 1932 (see Therese M. Kitt, Minneapolis; Hollis E. Valerie K. Ulstad. article, p. 10), on campus for their 50th Krug, Minneapolis; Diane L. Liljegren. Dr. O'Connor and Dr. Ulstad spoke reunion. Associate Dean H. Mead Duluth: Elizabeth P. Loken-Egdahl, for the class of '82. Dr. Ulstad reminded Cavert announced the many awards Ada; Susan K. Nelson, Jane Nolting­ her classmates of the stages in their de­ and honors won by members of the Brown; Elizabeth R. Seaquist, Min­ velopment as physicians: " ... the first graduating class: neapolis: Valerie K. Ulstad. Edina: Deb­ baby you delivered ... the first patients - The Medical Student Achievement orah Ann Wheeler. Virginia; and Rober­ who shared their fear with you and Awards (see article, p. 24); ta L. Zimmerman. Hibbing; treated you as their doctor . . . " Dr. - The Ruth Boynton Memorial -The AEI Honor Award. to the 0' Connor looked ahead, to a lifetime of Scholarship, given for academic excel­ senior woman medical student who learning: "We must continue to be stu­ lence, to Alyce M. Hamilton, of Many best exemplifies excellence in clinical dents of medicine," he said, and re­ Farms, Arizona; performance, community service, schol­ minded his classmates of the need for - The Nicollet Clinic Founders' arship, and leadership, to Deborah Ann humility. Scholarship, given for academic excel­ Wheeler. Erwin L. Goldfine, Duluth, Regent of lence to Susan K. Nelson of Red Wing, Anthony Bechik, President of the the University, conferred degrees, and and Jane Nolting-Brown, of Kenosha. Minnesota Medical Foundation. pre­ graduates were hooded, congratulated, Wisconsin; sented two awards: to Alyce M. Hamil­ and sometimes hugged by W. Albert - The New York Life Scholarship, ton the Gail Parker Eady Memorial Sullivan, Jr., M.D., Associate Dean of given for academic excellence, to Award, given in memory of the late Dr. the Medical School; Pearl P. Rosen­ Wayne H. Jarvis, of Owatonna, and Eady, a 1980 graduate; and to Peter J. berg, Ph.D., Assistant Dean; James H. Rolf N. Sigford, of Minneapolis; Dehne!, of Minneapolis. the 1982 House, M.D., Professor of Orthopaedic - The American Cancer Society Undergraduate Research Award. The Surgery; and Ronald Soltis, M.D., Assis­ Scholarship, given for interest in cancer Gail Parker Eady Award is given tant Professor of Medicine. research, to Elaine A. Barrios, of Sac­ annually to the minority student who ramento, California; best exemplifies the late Dr. Eady' s ideal In a charming departure from the - The Southern Minnesota Medical of service to her fellow students, and the program, Regents' Professor of Astron­ Association Outstanding Senior Award recipient is chosen by fellow students. omy Edward P. Ney was called to the to Craig A. Walden, of Garvin; The Undergraduate Research Award stage to hood his daughter, Dr. Judith - The J. Thomas Livermore Memo­ was won by Dr. Dehne! for his paper. A. Ney. The new doctors were pre­ rial Award for outstanding research in ''Alterations in Glycosaminoglycan sented with wallet-sized copies of their hematology, won in 1981 by Candy S. Metabolism in Puromycin-Amino­ diplomas by the Minnesota Medical Abramson, Duluth, and in 1982 by nucleoside-induced Nephrotic Syn­ Foundation. Marie E. Steiner, Rochester; drome.'' Slightly more than 25% of the Class - The Janet M. Glasgow Memorial Graduating members of the Medical of '82 are women, and the proportion Award, given to the outstanding women Student Council included Lucinda J. of women in the Medical School is in the graduating class by the American Conroy, Minneapolis, President; There­ rising; 35% of current medical students Medical Women's Association, Inc., to sa M. Thorn, Northfield, Parliamentar­ are women. There are no marked dis­ Candy S. Abramson Duluth; Susan D. ian (Dr. Thorn served on the Medical tinctions between men's and women's Adamson, Thief River Falls; Dana L. Student Council for three of her four choice of specialty. Battles, Minneapolis; Kathleen S. Farah, years); Stuart J. Fischbein, St. Louis Most University of Minnesota Medical 1 BANASZAK, LLOYD J. Wayzata U of M/Morris Hennepin County Medical Center Family Practice BANGSTON. BRADLEY R. Hopkins UofM U of M Hospitals Anesthesiology BANNER. EDWARD A. Rochester Harvard MMF President Bechik congratulates, left, Dr. Hamilton, and, right, Dr. Dehne/. U of Texas Affiliated Hospitals Houston Anesthesiology BARNES. MATTHEW J. Aurora School graduates remain in the state. ABRAM. LEON J. Gustavus Adolphus Will the practice of medicine in Minne­ Duluth U of M/North Memorial Hospitals sota be changed. when a quarter of the U of M/Duluth Family Practice St. Joseph's Hospital state's doctors are women? It is too BARRIOS. ELAINE A Denver soon to say. but Assistant Dean Pearl Sacramento, CA Surgery Rosenberg says, "On the evidence. U of California/Davis women are more interested in com­ ABRAMSON. CANDY S. Valley Medical Center munity concerns .... As a consequence. Duluth Fresno we may be seeing broader, more holis­ U of M Pediatrics Barnes Hospital tic health care." BATTLES. DANA L. St. Louis Minneapolis Internal Medicine "A Sense of Humor" U ofM Commencement speaker Norman ADAMS. JEFFREY L. U of Washington Affiliated Hospitals Shumway. M.D., Ph.D .. Professor and Eveleth Seattle Head of the Department of Car­ Hamline Internal Medicine Duluth Family Practice Res. diovascular Surgery at Stanford Uni­ BELL VILLE, JOHN K. Family Practice versity School of Medicine, urged the Minneapolis new doctors to preserve their sense of ADAMSON. SUSAN D. U of M humor. "Medicine is one of the great Thief River Falls Menninger Foundation exciting professions." he said. "Good Bemidji State Topeka. KS judgment comes from experience. but U of M/Methodist Hospitals Psychiatry Family Practice experience comes from bad judgment. BERG. JOHN C. . . . Be not merely competitive; move AD LIN. MARILYN S. Stillwater the practice of medicine to new Minneapolis U of M heights." UofM Fitzsimmons Army Center Dr. Shumway, noted cardiac trans­ Hennepin County Medical Center Aurora. CO plant surgeon (see article on p. 21). is a Family Practice Internal Medicine distinguished alumnus of the University. ANDERSON. BLAIR M. BERG, JONATHON H. After receiving his M.D. from Vander­ Bloomington Albert Lea bilt. he came to Minnesota for his in­ U ofM St. Olaf ternship and residency and also earned Hennepin County Medical Center Saginaw Cooperative Hospital a Ph.D. in cardiovascular physiology. Internal Medicine Saginaw. Ml Family Practice At the end of the formal program. the ARNEY. JOEL W. audience sat in respectful silence while La Crescent BERGMAN. THOMAS A Dean Sullivan administered the Oath U of Wisconsin/LaCrosse Duluth Princeton for New Physicians. The organist, Assis­ U of M Hospitals U of M Hospitals Anesthesiology tant Professor of Medicine Wesley Mil­ Surgery ler. played a triumphant recessional and ASHPOLE. DAVID K. the graduates burst into the sunlight of BERGSTEIN, JACK M. LeSueur Minneapolis the Northrop Mall and the world of UofM U ofM medicine. SW Michigan Area Health Ed. U of M Hospitals Kalamazoo. MI Surgery Internal Medicine BIROS, MICHELLE H. AUTREY. ALAN W. Minneapolis St. Cloud College of St. Catherine Here are the graduates· names, home St. John's U of Cincinnati Medical Center towns. undergraduate colleges. and Hennepin County Medical Center Ohio places and types of residencies: Family Practice Flexible BONGARD, BONNIE F. COUSINS, RANDY J. DREVLOW, LAUREL E. FILIPOVICH, JOHN T. St. Louis Park Minneapolis Twin Valley St. Paul Northwestern U of M U ofM U of M Butterworth Hospital U of M/North Memorial Hospitals Abbott-Northwestern Hospital U of M/St. John's Grand Rapids, MI Family Practice Internal Medicine Family Practice Flexible COWAN, CHRISTOPHER L. DUGINSKI, THOMAS M. FISCHBEIN, STUART J. BONNER, TIMOTHY C. Apple Valley Moorhead St. Louis Park Grand Rapids U ofM Moorhead State UofM St. John's Letterman Army Medical Center Wilford Hall Medical Center Cedars-Sinai Medical Center Hennepin County Medical Center San Francisco San Antonio, TX Los Angeles Flexible Radiology Internal Medicine Obstetrics/Gynecology

BREZNIK, JOHN D. CRAGG, ANDREW H. ECKMANN, DAVID R. FISCHER, MARK D. Edina St. Paul Burnsville St. Paul U ofM St. John's U of M/Morris College of St. Thomas St. Mary's Hospital U of M Hospitals U of M Hospitals Tucson Hospitals Grand Rapids, MI Radiology Obstetrics/Gynecology Arizona Family Practice Flexible ENDRES, STEPHEN M. BRIDEN, MARIE E. DAHL, DAVID C. Austin FLEMING, RICHARD H. Edina Minneapolis St. Mary's Richfield Mt. Holyoke St. Olaf Mayo Graduate School of Medicine St. John's Hennepin County Medical Center U of M Hospitals Rochester U of M/St. John's Hospitals Dermatology Internal Medicine Anesthesiology Family Practice

BRYAN, ROY G. DALVE, RICHARD D. ERICKSON. PAUL F. FLETCHER, DEBORAH G. Mahtomedi Sacramento Minneapolis Minneapolis Coe College U of CA/Davis Macalester U of M McKennan Hospital Good Samaritan Hospital Duluth Family Practice Res. Hennepin County Medical Center Sioux Falls, SO Milwaukee Family Practice Internal Medicine Family Practice Family Practice ERICKSON, PETER J. FOX, WILLIAM D. CAHILL, TERENCE P. DAVIS, DAVID A. Roseville Duluth U ofM Milwaukee Minneapolis U of M/Duluth Sioux Falls Family Practice Res. Drake Macalester U of M/Bethesda Hospitals Naval Regional Medical Center VA Wadsworth Medical Center South Dakota Family Practice Charleston, SC Los Angeles Family Practice Family Practice Internal Medicine ERIE, JAY C. FRANZEL. JAMES R. Mound CARLSON, MARK C. DEHNEL, PETER J. Crookston St. Olaf Aitkin Bloomington St. Olaf Gustavus Adolphus Hennepin County Medical Center Hennepin County Medical Center U ofM Family Practice U of M/Bethesda Hospitals U of M Hospitals Flexible Family Practice Pediatrics FAHEY, JOSEPH B. FREEMAN, JAMES P. Little Falls CASTRO, DANIEL B. DERAUF, BRUCE J. St. Paul UofM Los Angeles St. Paul College of St. Thomas Hennepin County Medical Center Stanford St. Olaf Medical College of Wisconsin Internal Medicine LA County/Harbor-UCLA Mary Imogene Bassett Hospital Milwaukee Medical Center. Los Angeles Cooperstown, NY Anesthesiology Family Practice FREEMAN, RICHARDS. Flexible FARAH, KATHLEEN S. St. Paul CEYNOWA, TIMOTHY P. Prior Lake Cornell U Perham DICK, STANLEY P. College of St. Scholastica Emanuel Hospital St. John's Mountain Lake St. Paul-Ramsey Medical Center Portland, OR St. Paul-Ramsey Medical Center Augsburg Family Practice Flexible Family Practice U of South Dakota Affiliated Hospitals, Yankton, SO CHANG, EDWIN M. Surgery Minneapolis U ofM DOSLAND, THOMAS A. Ohio State U Hospitals, NewUlm Columbus, OH St. Olaf Neurosurgery Hennepin County Medical Center CONROY, LUCINDA J. Internal Medicine Minneapolis Stanford DOUGHERTY, LEAH E. U of M Hospitals Benson Internal Medicine St. Olaf Taking year off CORREA, RONALD J. Torrance, CA DRAKE, D. GORDON California State U/Los Angeles Minneapolis Western Medical Center Notre Dame Santa Ana, CA U of M Hospitals Family Practice Diagnostic Radiology HANSON, PAMELA J. FREUND, JOSEPH M. GOLDBLATT, DANIEL M. GRIEBIE, MATTHEW S. Minneapolis 4 Brooklyn Center St. Louis Park Hutchinson Carleton St. Olaf Carleton U of M/Monis U of Cincinnati Medical Center St. Joseph Mercy Hospital Taking year off Hennepin County Medical Center Surgery Family Practice Mason City, lA GOLDISH, GARY D. Family Practice St. Paul GROVES, NANCY L. HARMON, RONALD A. Sacramento GARDNER ROBERT N. U of M Granite Falls Butterworth Hospital Hamline California State Minneapolis U of California/Davis Affiliated Grand Rapids, MI U of M Hospitals U of M Hospitals. Sacramento Iowa Lutheran Hospital Flexible Anesthesiology Surgery Des Moines GONZALES, FELIX E. GUADARRAMA. MICHAEL A. Family Practice HART, PATRICIA A. Minturn, CO Naco, AZ St. Paul GAUTHIER ROBERT L. U of New Mexico U of California/San Diego U of Arizona Affiliated Hospitals Radcliffe Rochester U of California/Irvine Affiliated McGaw Medical Center Gustavus Adolphus Tucson Hospitals, Orange, CA Chicago Medical Center Hospital of Surgery Family Practice Internal Medicine Vermont. Burlington, VT GOODMAN, AVIEL L. Surgery HAATVEDT, CY B. HAVEL, PAUL E. St. Paul Fergus Falls GILBERTSON, CRAIG L. Swarthmore Minneapolis College of St. Teresa U ofM Duluth Institute of Living Youngstown Hospitals Gustavus Adolphus Hartford, CT Hennepin County Medical Cen Ohio Flexible Duluth Family Practice Res. Psychiatry Flexible Family Practice GOSEN. KAREN M. HAYNES, GREGORY D. HAGEDORN, LYNN A. GILBERTSON, JEFFREY J. Little Falls La Puente, CA St. Cloud St. Paul Drake California State College St. Cloud State Dartmouth Mayo Graduate School of Taking year off St. Paul-Ramsey Medical Center U of Utah Affiliated Hospitals Medicine, Rochester Obstetrics/Gynecology Salt Lake City Internal Medicine HEMPEL, STEPHEN L. Surgery Brooklyn Center GRAYDEN, THOMAS J. HALVERSON, LYNNE M. St. John's GILBERTSON, REID A. Excelsior Madelia U of Michigan Affiliated Hospit Bloomington Arizona State Hamline Ann Arbor, MI Bemidji State U of North Dakota Hospitals U of California/Davis Hospitals Internal Medicine U of M!Bethesda Hospitals Sacramento Grand Forks Family Practice Psychiatry Family Practice HERMANSON, BRUCE A. GLASS, ALAN I. Richfield HAMIL TON, ALYCE M. Rochester GREEN, EDDIE L. St. Olaf Many Farms, AZ U ofM Belzoni, MS U of Pittsburgh Affiliated Hospi1 University of Cincinnati Medical Millsaps College Macalester Psychiatry Abbott-Northwestern Hospital Center. Ohio U of M Hospitals Pediatrics Internal Medicine Internal Medicine HESSE. JEANNE M. Staples Concordia St. Paul-Ramsey Medical CentE Family Practice

HILL, RICHARD S. Minneapolis Northwestern Albany Medical Center New York Otolaryngology HOGAN, TIMOTHY M. St. Paul St. John's Sioux Falls Family Practice Re~ South Dakota Family Practice HOMAN, HERBERT A. South St. Paul College of St. Thomas U of M/Bethesda Hospitals Family Practice

HOWE, JOHN B. Crystal U of M/Duluth St. Joseph's Hospital Marshfield, WI Flexible Norman Shumway addresses the graduates.

KITT, THERESE M. LEAVENWORTH, NANCY M. 5 Minneapolis Excelsior Augsburg Carleton U of Iowa Hospitals Hennepin County Medical Center Iowa City Flexible Internal Medicine LEONARD, THOMAS J. KOLARS, JOSEPH C. St. Paul Edina St. John's College of St. Thomas LaCrosse Lutheran Hospital U of California-San Diego LaCrosse, WI Affiliated Hospitals Internal Medicine Internal Medicine LEUKUMA, MARY A. HUDRLIK, TAMARA L. JOHNSON, GARNER P. KOSIAK, JOHN A. Excelsior Owatonna Rochester Minneapolis U of M U ofM Brown U of M U of M Hospitals U of M Hospitals U of Chicago Clinics St. Paul-Ramsey Medical Center Pediatrics Obstetrics/Gynecology Surgery Flexible LILJEGREN, DIANE L. HURD, RANDALL C. Duluth JOHNSON, GREGORY J. KRAMER, GEORGE H. Carleton Minneapolis Rochester Excelsior Carleton U of M Hospitals U ofM U of M Family Practice U of M/St. Mary's Hospitals Presbyterian-St. Luke's Hospital Mayo Graduate School of Family Practice Denver Medicine. Rochester LINDQUIST, MARK D. ILIKA, KAREN L. Flexible Otolaryngology Moorhead Bloomington Concordia KRAUSE, JAMES St. Olaf JOHNSON, JEAN A. R. Sioux Falls Family Practice Res. St. Paul Minneapolis Madigan Army Medical Center South Dakota Reed College Carleton Seattle Family Practice Michigan State U Associated St. Paul-Ramsey Medical Center Obstetrics/Gynecology Hospitals, East Lansing. MI Obstetrics/Gynecology LITWACK, ROBERTS. INMAN, STEVEN V. Internal Medicine Minneapolis Minneapolis KRUG, HOLLIS E. U of M U ofM JOHNSON, STUART B. Minneapolis Maricopa County General Hospital U of Colorado Affiliated Hospitals Bloomington U of Northeast Phoenix Denver Bethel U of M Hospitals Internal Medicine Pediatrics U of M Hospitals Internal Medicine LOKEN-EGDAHL, ELIZABETH P. Internal Medicine JANES, PETER C. LANGE, DANNY B. Ada Rochester JOHNSON, VICTORIA A. Harmony St. Olaf U ofM Deephaven Augsburg UCLA Neuropsychiatric Institute Presbyterian/St. Luke's Hospital St. Olaf Abbott-Northwestern Hospital Los Angeles Denver Dartmouth/Hitchcock Medical Internal Medicine Psychiatry Flexible Center, Hanover, NH LUDWIG, ANN M. Internal Medicine LANGER, MAREN L. JARVIS, WAYNE H. Minneapolis Cannon Falls Owatonna KAIHOI, DEAN A. Stanford College of St. Catherine U ofM Minneapolis Taking year off McKennan Hospital U of Kentucky Medical Center Bethel College Sioux Falls, SO Internal Medicine Lexington, KY U of M/Methodist Hospitals LANNON, CAROLE M. Surgery Family Practice Glen Ellyn, IL LUNDSTEN, THOMAS L. Macalester JEDDELOH, NEIL P. Bemidji KARNES, WILLIAM E. North Carolina Memorial U of M/Duluth St. Paul Rochester Hospital. Chapel Hill, NC Gustavus Adolphus U of M/St. John's Hospitals U ofM Flexible Family Practice U of M/North Memorial Hospitals U of M Hospitals Family Practice Internal Medicine LARSON, DAVID D. LYSNE, DWIGHT H. Fridley Moorhead· JENSEN, JOEL B. KEATING, MICHAEL R. U of M Moorhead State Minneapolis Rochester Mercy Hospital Dordt College U of California-San Diego Affiliated Colorado College San Diego, CA Hospitals U of M/North Memorial Hospitals Mayo Graduate School of Flexible Surgery Family Practice Medicine, Rochester JOHNSON, ALBERT D. Internal Medicine Virginia KEUL, THOMAS J. U ofM Duluth U of California-San Diego Affiliated UofM Hospitals U of M Hospitals Surgery Psychiatry JOHNSON, BRADLEY S. KILBURG, ELIZABETH A. Brooklyn Park Minneapolis U ofM U of Wisconsin St. Paul-Ramsey Medical Center U of M Hospitals Family Practice Obstetrics/Gynecology

Class president Cindy Conroy. MacDONALD, SUZANNE McLELLAN, DANIEL S. MOOS, MALCOLM C. NELSON, SUSAN K St. Paul Minneapolis St. Paul Red Wing U of Wisconsin St. Olaf Stanford St. Olaf Abbott-Northwestern Hospital U of M Hospitals U of M Hospitals U of M Hospitals Internal Medicine Pediatrics Pathology Psychiatry MacDUFF, MARIA I. MELCHER, GREGORY P. MORIN, WILLIAM D. Coleta, CA Buffalo White Bear Lake NERENBERG, LEX A. U of Pittsburgh U ofM U ofM Minneapolis U of Washington Affiliated Wilford Hall Medical Center Naval Regional Medical Center U ofM Hospitals. Seattle San Antonio, TX San Diego Hennepin County Medical Cer-1: Anesthesiology Internal Medicine Surgery Internal Medicine MacLEAN. DOUGLAS G. Minneapolis UofM U of MiSt. Mary's Hospitals Family Practice MADDAUS. MICHAEL A. Minneapolis U ofM U of M Hospitals Surgery MADDY. MICHAEL M. Duluth Carleton Hennepin County Medical Center Internal Medicine MALOTKY. RICHARD A. Minnetonka St. Olaf St. Michael Hospital Milwaukee Graduates Mark Fisher, left, Cindy Conroy, and Tom Dosland Family Practice with Dean Gault at the Dean's reception.

MANLOVE. JEFFREY C. MELLER WILLIAM H MROSAK DANIEL R NEUMANN, MARY P. St. Paul Edina Minneapolis Plymouth Carroll College Carleton U of M Gustavus Adolphus Mayo Graduate School of Medicine U of Iowa Hospitals U of Missouri-Truman Medical U of M Hospitals Rochester Iowa City Center, Kansas City, MO Pathology Otolaryngology Psychiatry Surgery NEY, JUDITH A. MANLOVE, STEPHEN P. MEURER ALLEN G. MUELLER MICHAEL L Minneapolis Eden Prairie Austin Shoreview U of M St. Olaf U of M/Duluth U ofM Mayo Graduate School of U of Virginia Medical Center Mayo Graduate School of Medicine William A. Shands Hospital & Medicine, Rochester Charlottesville, VA Rochester Clinic, Gainesville, FL Obstetrics/Gynecology Psychiatry Internal Medicine Anesthesiology NICOSKL RICKY A. Sartell MAYER ALAN D. MEYERS, BRYAN D. MULVAHILL, AMY S. Rochester St. John's Virginia Golden Valley Wausau Hospital Center-U of U ofM U of M/Duluth Tufts U of Colorado Affiliated Hospitals Marshfield-U of Wisconsin Affiliated Wisconsin Affiliated Hospitals U of M Hospitals Wausau, WI Ft. Collins. CO Hospitals Internal Medicine Family Practice Surgery Family Practice MURN, MELANIE C. NIELSON, SKOTT N. McCONNELL, CAMERON MICKMAN, JAMES K St. Cloud Farmington Wayzata Fridley U ofM Gustavus Adolphus St. Olaf U of M U of M Hospitals Maricopa County General Hos U of MiBethesda Hospitals Hennepin County Medical Center Obstetrics/Gynecology Phoenix Family Practice Internal Medicine Flexible McCROSSAN, MARY C. MIETTUNEN, JAMES B. NAWROCKI, JOSEPH W. NISSWANDT, ERIC A. St. Paul Hibbing Trimont Knife River Macalester Concordia Southwest State U of M/Duluth U of M;North Memorial Hospitals Mayo Graduate School of Medicine Sioux Falls Family Practice Res. SW Michigan Area Health Ed. Family Practice Rochester South Dakota Kalamazoo, Ml Otolaryngology Family Practice McD\NALD. DOUGLAS J. Flexible Albert Lea MONTBRIAND, JOEL R NELSON, KAREN L NOLTING-BROWN. JANE St. John's White Bear Lake Spicer Kenosha, WI Mayo Graduate School of Medicine Ham line Augsburg Valparaiso Rochester Hennepin County Medical Center U of M Hospitals U of M!North Memorial Hospil Orthopaedic Surgery Internal Medicine Psychiatry Family Practice NOMELAND, DAVID L. OSTLUND, MARK L. PFAFF, JAMES A. Osakis Minneapolis Columbia Heights U of M/Duluth U ofM St. John's Blodgett Memorial Medical Center U of Washington Affiliated Tripier Army Medical Center Grand Rapids, MI Hospitals, Seattle Honolulu, HI Obstetrics/Gynecology Internal Medicine Flexible NOONAN, DANIEL E. PAST, LARRY R. PLUMMER. DAVID W. Robbinsdale Minneapolis Edina College of St. Thomas U ofM St. Olaf U of M/North Memorial Hospitals Abbott-Northwestern Hospital Hennepin County Medical Center Family Practice Internal Medicine Flexible PAULSON, GARY L. NORGARD. RANDALL J. POOLER, PETE A. Glenwood St. Louis Park Duluth U of M/Morris College of St. Scholastica St. Olaf Hennepin County Medical Center U of M Hospitals Veterans Administration Hospital Surgery Minneapolis Internal Medicine Orthopaedic Surgery PAWLIK, MICHAEL J. PRIMROSE, DAVID C. Minneapolis Bloomington U ofM NORMAN, MATTHEW E. Maca! ester U of M Hospitals Minneapolis SUNY -Upstate Medical Center College of St. Thomas Internal Medicine Syracuse. NY Val Ulstad addressed her Hennepin County Medical Center PEARSON, GLENN E. Surgery classmates. Flexible Minneapolis QUADAY. JAMES W. ROGIN, ROBYN L. O'BRIEN, WILLIAM A. UofM Blue Earth St. Louis Park Edina Presbyterian Denver Hospital Denver U ofM U ofM MIT Hennepin County Medical Center Emanuel Hospital VA Wadsworth Medical Center Internal Medicine Internal Medicine Portland, OR Los Angeles PENROSE-MILLER, ALICE P. Flexible Internal Medicine Minneapolis REHBEIN, MICHAEL S. Queens U Bloomington ROSENSTEIN. ALEXANDER D. O'CONNOR, SCOTT J. St. Joseph Mercy Hospital Valparaiso St. Louis Park Duluth Ann Arbor, MI Travis AFB!David Grant Medical U ofM St. Olaf Internal Medicine Center, Fairfield. CA U of California-San Diego Affiliated Hennepin County Medical Center Pediatrics Hospitals Surgery PETERSON, BRADLEY J. Rushford REMARK, RICHARD R. Orthopaedic Surgery OGLE, KATHLEEN M. St. Olaf Fertile ROWE. SCOTT C. Minneapolis U of M Hospitals Concordia Minneapolis U ofM Anesthesiology U of New Mexico Affiliated Hospitals U of M U of M Hospitals PETERSON, DEBRA G. Albuquerque U of North Dakota Affiliated Internal Medicine Edina Internal Medicine Hospitals, Fargo, NO OLMANSON. DOUGLAS V. Luther College RENIER, HUGH P. Family Practice St. Peter Sioux Falls Family Practice Center Duluth SAKO, EDWARD Y. U of M South Dakota U of M/Duluth St. Paul U of M/St. Mary's Hospitals Family Practice Duluth Family Practice Res. U of M Family Practice PETERSON, MARGIE H. Family Practice U of M Hospitals Cannon Falls Surgery OLSON, MARY L. RHOLL, KENNETH S. U of Wisconsin/River Falls Golden Valley Madison Eau Claire Regional Consortium SAMLASKA, CURT P St. Olaf Gustavus Adolphus Madelia Eau Claire, WI Barnes Hospital/Washington U U of M/St. Mary's Hospitals Family Practice Mankato State Family Practice Hospitals, St. Louis Tripier Army Medical Center PETERSON, TIMOTHY M. Diagnostic Radiology Honolulu, HI OLSON, RUSSELL J. Benson Internal Medicine Cokato U of M/Morris RICE, MARGARET I. Mankato State Sioux Falls Family Practice Center Minneapolis SANDALL. PAUL G. U of M/Methodist Hospitals South Dakota U of Pennsylvania Minneapolis Family Practice Family Practice U of M Hospitals U of Wisconsin/Madison Internal Medicine St. Paul-Ramsey Medical Center RINIKER, ROBERT P. Psychiatry Minneapolis SCHMIDT, BRIAN E. U of Colorado Fergus Falls Hennepin County Medical Center U ofM Internal Medicine Abbott-Northwestern Hospital Internal Medicine RITTS, GRAHAM D. Rochester SCHNEIDER, DAVID E. Princeton Bloomington Mayo Graduate School of Medicine U ofM Rochester Hennepin County Medical Center Orthopaedic Surgery Family Practice As did Scott O'Connor. 7 STANGL, DOUGLAS V. THOMAS, SCOTT D. Claremont Rochester Mankato State U of M/Duluth Siouxland Medical Foundation Presbyterian-St. Luke's Hospital Sioux City, lA Denver Family Practice Flexible STARZINSKL DONALD T. THORN. THERESA M. St. Paul Northfield U of M U ofM U of M Hospitals U of Oregon Health Sciences Cer Neurology Portland, OR Internal Medicine STAUB, DAVID B. Minneapolis THORSGARD, KNUTE E. U of M Thief River Falls Mission Hospital Concordia Tandala, ZaYre U of North Dakota Affiliated Tropical Medicine Hospitals. Grand Forks. ND Family Practice STEIN, STEVEN D. Eivind Hoff, right, executive director of the Minnesota St. Paul TILBURY. RALPH T. Medical Foundation, congratulates Peter Dehne/, winner U of M Minneapolis of the MMF's Undergraduate Research Award. Abbott-Northwestern Hospital U ofM Internal Medicine Hennepin County Medical Cent SCHNELL. WILLIAM F. SIEMERS, ROSS F. Internal Medicine Litchfield Richfield STEINER MARIE E. Gustavus Adolphus St. John's Rochester TOSTESON, DAVID J. Medical College of Wisconsin Marshfield/U of Wisconsin St. Olaf Minneapolis Affiliated Hospitals Affiliated Hospitals U of M Hospitals U ofM Milwaukee Internal Medicine Pediatrics U of M/Methodist Hospitals Orthopaedic Surgery Family Practice SIEVERT, WILLIAM S. STOCKS, JEANNE M. SCHULLER ELDON M. Minneapolis Minneapolis TRUDE, TIMOTHY E. San Francisco U of M St. Olaf Duluth U of California/Davis St. Paul-Ramsey Medical Center Abbott-Northwestern Hospital Bethel College LA County/USC Medical Center Family Practice Internal Medicine U of M/Bethesda Hospitals Los Angeles Family Practice Flexible SIGFORD, ROLF N. STONE, SARAH L. Minneapolis Lake City ULSTAD, VALERIE K Edina SCHULTZ. STEPHEN M. U of M Michigan Technical U Winona Abbott-Northwestern Hospital U of Oregon Health Sciences St. Olaf St. Mary's Internal Medicine Center, Portland. OR U of M Hospitals Rush-Presbyterian-St. Luke· s Internal Medicine Internal Medicine Hospital. Chicago SIMONSON, JAYS. UNSER STANLEY H. Internal Medicine Prior Lake STRAND, MARILYN H. Oak Park Heights U ofM Morris U of M SEAQUIST. ELIZABETH A U of California Hospitals U of M/Morris Minneapolis Letterman Army Medical Cente San Francisco St. Paul-Ramsey Medical Center San Francisco Vassar Internal Medicine Pathology U of M Hospitals Flexible Internal Medicine SMITH. ANTHONY E. SVOBODNY, CYNTHIA LARSON VECHELL, DANIEL S. Edina Buffalo Chisholm SHANK JUDITH F. UofM Gustavus Adolphus Augsburg Minneapolis Hennepin County Medical Center U of M Hospitals Brooke Army Medical Center U of Iowa Family Practice Internal Medicine Denver U of M Hospitals Radiology Dermatology SMYRK THOMAS C SWANSON. TIMOTHY V. Rochester Minneapolis VON RUEDEN, KURT W. SHENK JOHN S. U of M St. Paul Wayzata UofM Mayo Graduate School of U of M Hospitals U of M Luther College Medicine. Rochester Pediatrics Rush-Presbyterian-St. Luke· s Hennepin County Medical Center Pathology HospitaL Chicago Surgery SYVERSON. DALE L. Orthopaedic Surgery SHOWERS. SIDNEY G. SORENSON, DIANE L. Cannon Falls VOSS. STEVEN H. Edina Albert Lea U of M Minnesota Lake Iowa State U of M U of Oregon Health Sciences St. John's U of M Hospitals Mayo Graduate School of Center, Portland. OR U of M/Bethesda Hospitals Pediatrics Medicine, Rochester Surgery Family Practice Internal Medicine SIELENL BRUCE A TALBERT. KENNETH E. WALDEN, CRAIG A West St. Paul STAHL. THOMAS J. St. Paul Garvin College of St. Thomas Bloomington Grinnell U of M/Morris U of Iowa Hospitals U ofM Rush-Presbyterian-St. Luke's Strong Memorial Hospital Iowa City U of M Hospitals Hospital, Chicago Rochester, NY Psychiatry Surgery Ophthalmology Internal Medicine 8 WALDRON, JOHN B. WELD, JUDY L. WILLERSCHEIDT, ANTON B. Minneapolis Minnetonka St. Paul UofM U of M/Duluth College of St. Thomas St. Paul-Ramsey Medical Center VA Medical Center Hennepin County Medical Center Family Practice Martinez, CA Flexible Internal Medicine WALKUP, JOHN T. WILLSON. STUART L. Minneapolis WEXLER, DEBORAH L. Minneapolis U ofM Minneapolis U of Wisconsin Yale-New Haven Medical Center U of M LA County/USC Medical Center New Haven, CT Eau Claire Regional Consortium Los Angeles Psychiatry Eau Claire, WI Internal Medicine Family Practice WALLER, STEVEN P. WEXLER, MICHAEL R. WOLTER, TIMOTHY J. Minneapolis St. Louis Park Minneapolis U ofM U of M Augsburg UCLA Hospitals and Clinics U of M Hospitals Sioux Falls Family Practice Center Los Angeles Pediatrics South Dakota Pediatrics Family Practice WHEELER, DEBORAH ANN P. WALSH, JOHN J. Virginia WOODWORTH, RANDON B. Duluth U ofM Winona St. Mary's U of Michigan Affiliated Hospitals St. Francis Medical Center Lawrence Ann Arbor, MI U of MISt. Mary's Hospitals LaCrosse, WI Anesthesiology Family Practice Family Practice WIECKS, MICHAEL J. WEBER, JAN C. Westbrook WORKMAN, CHARLES M. Isle Georgetown St. Paul Judson College UCLA-San Fernando Valley Hospitals U of M U of M Hospitals Los Angeles U of M/St. John's Hospitals Neurology Internal Medicine Family Practice WEINSTOCK, HENRY WILKOWSKI. MICHAEL J. ZIMMERMAN, ROBERTA L. Minneapolis Perham Hibbing U ofM Carleton College of St. Scholastica San Jose Hospital and Health Center U of Michigan Affiliated Hospitals United Hospitals San Jose, CA Ann Arbor, MI St. Paul Family Practice Internal Medicine Pathology

Note: For all those who counted names and found us one short: Dr. Richard Robinson, currently serving his residency at Hurley Medi­ cal Center, Flint, Ml, received his diploma in June although he was listed as a member of the Class of '81 in the Bulletin for Summer, 1981.

From left, Jim Boulger, associate dean of UMD School of Medicine, with graduates Tom Keul, Eric Nisswandt, and Brad Johnson (holding his daughter Lu) and UMD Dean Paul Royce. All these graduates are UMD alumni. q 10 Class of 1932

University of Minnesota Medical School 50th Anniversary Reunion June 3, 1982

Front, left to right: Elizabeth Conforth. Eva Shaperman Gordon, Aileen Petri. Rear, left to right: Reinhardt Schmidtke, Philip Gordon, Reuben Berman, Kenneth Olson, Russell Sather, Wallace Merritt, Earl Ellis, Cyrus Erickson, Albert Ritt.

Members of the Class of 1932, hold­ ent student body: The Medical School about 14 women in our class. out of ing their 50th reunion. were honored admits 239 students into the Phase A about 140, and three of us are here. guests at Commencement festivities. program: after two years 40 students That's pretty good, I think." The · 32 graduates attended their own from UM-Duluth's two-year medical "Beats the men." said Karin Petri. Reunion Dinner on June 3 at the Min­ school join the class. in Phase D. who practiced pediatrics in Houston. neapolis Club; they toured the Health Currently, 35% of medical students "but then. we always did!" Sciences Center and met again for are women, and 8% are members of The third alumna. Eva Shaperman lunch on June 4; and the class was in­ minority groups: Black. Native Amer­ Gordon. agreed. She too is retired. but troduced by Medical School Dean N. L. ican Indian. or Spanish-surnamed. her husband, Dr. Philip Gordon. still Gault as part of the 1982 graduation More Minnesota graduates enter pri­ practices physiatry in San Diego. Russell program. mary care specialties than the national Sather of Crookston still practices inter­ Co-chairmen Reuben Berman and AI average: 65% take their residency train­ nal medicine at Northwestern Clinic. but Ritt welcomed 12 classmates and their ing in Pediatrics, Obstetrics and Gyne­ most of the other classmates have re­ spouses to the reunion. For those who cology. Internal Medicine, or Family tired. hadn't visited the campus in recent Practice. And the rate of attrition over After two days of almost continuous years. like Dr. and Mrs. Kenneth Olson. the four years is only 2%, due mainly to excitement, reminiscence of teachers who divide their time between Gulf illness or changed family circumstances. and absent classmates, and comparing Stream. Florida, and South Bend. Indi­ "That's certainly a change from our of children and grandchildren, the 50th ana. the most astonishing development day,'' remarked AI Ritt. "We expected a reunion ended with dessert and coffee was "the (U of M West Bank) campus high wash-out rate." at the home of Dr. and Mrs. Berman. on the other side of the river!" "True: but we don't wash out medi­ The classmates of 1932 bid one another Even more recent visitors were per­ cal students any more," said Dean cheerful goodbyes, with, "See you in plexed by the streamlining of the Seven Gault. "We admit good students. and another 50 years.'' Corners area. 'T d never be able to find we want to see them all graduate." These members of the Class of · 32 my way around," said Cyrus Erickson. The Dean also lauded the Medical provided information about themselves: who now lives in Tennessee. School's distinguished departments of At lunch in the Campus Club on basic science, in which 250 graduate Reuben Berman retired from the pri­ Commencement Day. the '32 gradu­ students are currently enrolled in doc­ vate practice of internal medicine in ates met Dr. Donald Asp ('64). Presi­ toral degree programs. "Our Pharma­ 1980. but he still sees some patients and dent of the Medical Alumni Society. cology Department has the No. 1 does research in hypertension at Mt. and heard Dean Gault report on the graduate program in the US." he said Sinai Hospital in Minneapolis. He and current status of their school. He spoke (see p. 16), "and the others are not far his wife, Isabel. have six children. all proudly of Minneota· s high standing behind." graduates of the University of Minneso­ among US medical schools, and also "Let's see," said Elizabeth Conforth. ta; their three sons are all physicians. gave some information about the pres- who lives in San Diego, "there were "Music has been a lifelong hobby." he writes, "the clarinet since childhood, 11 and I changed to the bassoon six years ago." He is immediate past president of the Minnesota Medical Foundation.

Theodore J. Catlin and his wife. Shirley. live in Buffalo, Minnesota. He retired from general practice in 1968 and enjoys woodworking, gardening, and "cutting firewood." The Catlins have three daughters.

Elizabeth Conforth has practiced pathology for 35 years, "chiefly in San Diego and Los Angeles." She served as a "contract surgeon" for four years in an army hospital in Frankfurt when her husband was stationed in Germany with the US Army of Occupation. She and elude "the great opportunity and stimu­ Philip and Eva Shaperman Gor­ her husband are close to their seven lating experience of working as student, don, after many years of practice brothers and sisters and their "flocks of volunteer assistant, or research fellow together in Minneapolis. at the Gordon nieces and nephews." Among her hob­ under such great Minnesota faculty of Clinic, moved to San Diego to be near bies are "growing orchids, camellias, our era as E. T. Bell, Owen Wangen­ their pathologist daughter and their annuals, and strawberries. cooking, steen, Irvine McQuarrie. . . . and foot grandchildren. While still in Minneapo­ bridge, and playing the organ." ball under Bernie Bierman!" lis, Philip, a specialist in physical medi­ He and his wife. Bernice, have a son cine. took a residency in psychiatry. Eva Earl W. Ellis says that. before he re­ and a daughter. Hobbies include golf. retired from the practice of pediatrics tired from general practice in 1980, he gardening, "long-distance management when she moved to San Diego. was "the busiest physician in Wabasha of family farm and lakeshore near Alex­ 'Tm the only physician in San Diego County." He and his wife, Marvel. live in andria," and "periodic return to office to who still makes rounds every morning," Elgin. Minnesota; his most recent investigate records and follow-up of says Philip. "The younger doctors can't accomplishment was winning the Uterine Cancer Cytology Project - 30- understand it." Senior State Left-Handed Golf Tourna­ year follow-up!" ment in 1976; and he also enjoys Hugo V. Hullerman, after nearly 30 years as a hospital administrator in Illi­ gardening, playing the piano, and paint­ Muriel C. Gaffney has retired and nois and Michigan. retired with his wife, ing in acrylics. The Ellises have three lives in Silver Spring, Maryland. where Maurine, to Sun City, Arizona. There he married daughters. she enjoys "hard crossword puzzles, serves as chairman of the board of the reading the classics," and her nine chil­ Sun Health Corporation and on the Cyrus E. Erickson writes, "During dren and nineteen grandchildren. She board of the Boswell Memorial Hospi­ the past 45 years I have primarily did not attend the reunion because her tal. In his spare time he enjoys golf. 'bragged' about being a Minnesota youngest daughter, Kathy. was bridge, fishing, silver craft, and lapidary graduate!" After internship. residency, married June 5. Vivid memories of work. The Hullermans have two daugh­ and graduate training in pathology, in medical school include "Anatomy dis­ ters and five grandchildren. Minneapolis, Detroit, and Rochester, he section. From what I hear, it's a lot joined the faculty of Duke University neater now.'' H. P. Lenton is a Fellow of the Amer­ Medical School, where he stayed until ican College of Chest Physicians and a 1950. A lieutenant colonel in the Harold E. Gillespie, semi-retired in member of the American Society of In­ USRMC, he saw active duty in World Richmond, Virginia, served as Captain ternal Medicine. He and his wife live in War II with Duke's 65th General Hos­ (MC), US Navy, from 1932 to 1963. Carlisle, Pennsylvania. His outstanding pital Unit in the US (Fort Bragg), Eng­ aviation medicine his specialty. He won medical school memory ·is of "the first land, and Germany. seven campaign ribbons and six battle examination in physiology. and the In 1950, he moved to the University stars, and after leaving the service he question, 'What about a fog?'" of Tennessee, where he served the Col­ became assistant commissioner of the lege of Medicine and the Medical Units Virginia State Health Department. Of Alfred Merrill McCausland and his as professor, as head (1968-72), and as medical education he remembers physician wife, Frances Holmes director of the School of Cytotechnolo­ "being a junior intern at Northwestern McCausland. live in Los Angeles where gy (1951-75). Retiring in 1974, he is Hospital for 2 1/2 years." he practiced obstetrics and gynecology now Professor Emeritus. Among many He and his wife have three children, until his retirement in 1977. He reports, awards and honors he is particularly one a Lieutenant Commander (MC). "I am unable to be present at our reun­ proud of several awards from the Amer­ USN. He writes, "Nothing would please ion due to health problems (Parkin­ ican Cancer Society, the 1965 Papa­ me more than to attend and renew son's)." He is a Fellow of both the nicolaou Award, given by the American friendships"; however. the reunion con­ AAOG and the ACOG, and has been Society of Cytology, and a Distin­ flicts with the annual visit of his two very active in several professional guished Alumnus Award from Duke grandsons and "the boys are fishing age organizations in California. The (1972). and look forward all year to going out McCauslands have a son and a daugh­ His memories of medical school in- on Chesapeake Bay." ter, both physicians. 12 Russell 0. Sather has practiced in­ ternal medicine at Northwestern Clinic. Crookston. Minnesota, since 1937. ex­ cept for his five years of military service. He won a bronze star in the Spice Is­ lands. Southwest Pacific Theater. and was given the University of Minnesota's Harold Diehl Award in 1976. His most memorable experiences in medical school include "Instructor for 9 months with Dr. E. T. Bell - especially his en­ tertaining CPC conferences, clerkship under Dr. Hobart Reiman. and working with Dr. Francis Lynch in the outpatient dermatology clinic.'· He has a daughter and a son, who heads the Division of Family Practice at the University of Ala­ Wallace A. (Bud) Merritt practiced ophthalmology at the University of Min­ bama Medical SchooL and his hobbies internal medicine at the Mayo Clinic nesota Hospitals from 1945 to 1948. include traveL growing roses, photogra­ from 1938 until his retirement in 1976. and subsequently practiced ophthal­ phy, and Crookston community affairs. except for four years in the US Medical mology in Duluth until his retirement in He is a past Trustee of the Minnesota Corps during World War II when he 1979. About medical school he recalls Medical Foundation. served in New Guinea. the Philippines. "playing on the University hockey team and Tokyo. He still lives in Rochester. for three years and going through pre­ Jan H. Tillisch lives in Rochester, Minnesota. where he enjoys yard work med and medical education at the same Minnesota, where he has practiced in­ golf, and volunteer work. From medical time. A sense of satisfaction in having ternal medicine and aerospace medi­ school he has fond memories of "the been able to do it." He has one daugh­ cine. He and his wife have a daughter lectures and demonstrations of Drs. ter and his hobbies include "gardening. and a son. and his hobby is study of the Scammon. Rasmussen. and E. T. Bell." fishing. curling. walking. and reading." Civil War. He and his wife Thelma have a son and "I will do my best to attend the ban­ two daughters. quet." he wrote, but added that he was S. W. Watson writes that his "only "host for the 50th reunion of the survi­ accomplishment was rural general prac­ After practicing radiology for 34 years vors of the USS Hammann DD412 tice for 50 years and not being in South Bend. Indiana. Kenneth L. which was sunk at the Battle of Midway arrested." He and his wife live in Royal­ Olson retired to Gulf Stream. Florida. in in 1942. · · This reunion took place in ton, Minnesota, and he enjoys many 1976. He writes. "I enjoyed radiology. Duluth at the same time. hobbies. including photography, and was president of the Indiana Roent­ gardening, golf, hunting, and fishing. gen Society. and of the Indiana Medical Karin Aileen Petri had a distin­ What "stands out after 50 years." he Association in 1959-60." He served the guished career as a student: Rockefeller writes. are "Dr. Scammon's lectures in profession and the community in many Fellow at the University of Minnesota. embryology and clinical medicine under other volunteer capacities. such as the 1933-35: grantee from the Child Re­ Dr. George Fahr and Dr. Moses Bar- " Community Chest and the United Way. search Council, University of Colorado. ron. The Olsons have three daughters. 1935-37: and Sigma Xi. Now retired from her private pediatric practice in "Hard work and no money" is Houston. she remembers particularly A Class of '32 Fund was established. George E. Penn's outstanding memory "Dr. Richard Scammon's embryology stimulated by a generous gift from of medical school. Retired in 1972 from lectures. Dr. Esther Greisheimer' s help­ Dr. and Mrs. Ritt and the gifts of his practice of obstetrics and gynecology fulness and concern. and all the Pediat­ several others. The Fund has been in Mankato. Minnesota. George writes. ric Department, especially Dr. Irvine designated the Class of 1932 Loan "My greatest life reward has been my McQuarrie and Dr. Arild Hansen." She Fund and will be administered by the many satisfied patients." He and his has two sons and her hobbies include Minnesota Medical Foundation. second wife. Bess, have a son and a "gardening. fishing. traveling, and en­ According to Dr. Reuben Berman. daughter and three small grandchildren. joying my grandchildren." MMF Trustee and co-chair of the His main hobby is collecting: advertising class reunion, loans will be available pencils and yardsticks: antique tools. Albert E. Ritt, who retired from from the Fund to current medical stu­ medical instruments and books. and general practice in 1965, served as dents at educational rates of interest. musical instruments: china: and Amer­ President of the American Academy of Members of the Class of 1932 are ican pressed glass. He also likes to re­ Family Practice, 1963-1964, and was encouraged to contribute to the store and refinish antique furniture and active in the Ramsey County and Min­ Loan Fund, said Berman, by bequest to collect cut and study gemstones and nesota State medical societies and the or by current gift. other minerals. AMA. He remembers "Graduation To obtain information about tes­ Day'" as the outstanding event of tamentary gifts, contact the Minneso­ John H. Peterson started out in medical school. He and his wife have ta Medical Foundation, 535 Diehl general practice, but after serving as a three children and live in St. PauL HalL University of Minnesota, Min­ medical officer in the US Navy from where AI is President of the Midway neapolis, MN 55455. 1941 to 1945. he took a fellowship in National Bank. Reunion '82 13

Recognition of alumni who have made extraordinary contributions to the health sciences and to the university was also part of the spring reunions and celebrations.

For more recent alumni as well, the weekend provided opportunity to renew friendships and rekindle memories. Several classes held private celebra­ tions, like the Class of '47, for its 35th reunion. And the Medical Alumni Socie­ ty's cocktail party, on June 5, in the Ski­ U-Mah Room of the Minnesota Alumni Club, saw alumni, spouses, and friends happily mingling.

High points of the Annual Meeting of the University of Minnesota Medical Alumni Society, at its luncheon on June 5, 1982, were the presentation of the University of Minnesota Alumni Service Award to Clinical Emeritus Professor of Surgery William C. Bernstein, M.D. ('28), former President of the Society; the Harold S. Diehl Award for distfn­ guished service to S. Lane Arey, M.D. (' 32), Clinical Emeritus Professor of Pediatrics, and Kristofer Hagen. M.D.

Continued 14

('42), family practitioner and medical of the Division of Colon and Rectal for outstanding contributions to the field missionary: and a keynote address by Surgery. a post he held until he retired of colon and rectal surgery. John L. McKelvey, M.D .. Emeritus Pro­ in 1972. Eivind Hoff. Executive Director of the fessor of Obstetrics and Gynecology Dr. Bernstein's deep commitment to Minnesota Medical Foundation. pre­ Lunch was served to nearly 200 the University and to the Medical sented the Alumni Service Award to Dr. alumni and guests in the colorful Spec­ School are reflected in his service as a Bernstein in behalf of the University. trum Cafeteria in the Phillips­ faculty member and clinician, and as Diehl Awards Wangensteen Building, separating the Clinical Professor Emeritus he has con­ two sessions of the Alumni Society's tinued to serve the Department of The Harold S. Diehl Awards are given Postgraduate course, "New Horizons in Surgery as its Director of Special Proj­ annually by the Medical Alumni Asso­ Minnesota Medicine." Konald A. Prem ects. Notable among these special proj­ ciation in the name of the former Dean ('50) was Master of Ceremonies. Dr. ects have been his chairmanship of the of the Medical School. who died in Prem. Head of the Department of Ob­ Committee for the Construction of the 1973. They honor Minnesota physi­ stetrics and Gynecology, was the out­ Kidney Dialysis Center and the produc­ cians for outstanding service to their going President of the Medical Alumni tion of the documentary film, "Progress profession and their community. This Society. in Surgery through Research at the Uni­ year's recipients. Dr. Arey and Dr. versity of Minnesota." Hagen. are two shining examples of creative and committed service. Service Award He is a recipient of the Mt. Zion Humanitarian Award. the President's S. Lane Arey grew up in Minnesota The Alumni Service Award is the high­ Award for Distinguished Service from and graduated from medical school in est award the University grants to an the Minnesota Medical Association. and 1931. Although he trained as a pediatri­ alumnus for significant service to the in­ the Clifford Emerson Hardwick Award cian and took a pediatrics internship at stitution. Only four or five medical graduates have received it, including Virgil Lundquist ('43). William Bernstein (right) accepts the UM Alumni Service Award from Eivind Hoff. Dr. William C. Bernstein is former Director of the Division of Colon and Rectal Surgery in the Medical School. past President of the Alumni Society, as mentioned. and 1971 recipient of the Diehl Award. He holds three degrees from the University: B. S ( 1925 ), M. B. (1927). and M.D. (1928). From 1929 to 1940. Dr. Bernstein practiced family medicine in the south­ ern Minnesota community of New Rich­ land. His growing interest in diseases of the lower bowel, however. led him to the new field of colon and rectal surgery, and from 1940 to 1943 he was a voluntary Fellow in the Department of Surgery under Dr. Walter A. Fansler. After serving with the University's Medical Unit in Oak Ridge. Tennessee, during World War II, Dr. Bernstein was asked to head the new proctologic di­ agnostic and surgical service at the Min­ neapolis Veterans' Hospital in 1946. In 1958. he succeeded Dr. Fansler as chief 15

Children's Memorial Hospital in Chica­ go, Dr. Arey did not practice pediatrics until 1943. "My father died nine months after I began practice, and I took over his family practice out here in Minnetonka. Then the war came along, and I went into the Navy. I was dis­ Kristofer Hagen, left, and S. L. Arey,- right. charged in 1943, because I had TB, and I became a practicing pediatrician as served on the board of missions of the Other Health Sciences soon as I got over that." American Lutheran Church, checking Alumni Awards on the progress and development of Dr. Arey has also been a clinical Lutheran hospitals around the world. The Outstanding Achievement Award teacher since 1943. both at Minneapolis From 1965 to 1972, he also served as of the University of Minnesota Alumni General (now Hennepin County Medi­ an associate editor of Modem Medicine, Association was awarded to Gary Lewis cal Center) and at the University, and a the semi-monthly magazine for physi­ Filerman, Ph.D. (Epidemiology, '70), pioneer in pediatric allergy. His service cians that was then published in Edina. at the School of Public Health com­ through the Minnesota Medical Associa­ mencement on May 22, 1982. Dr. Filer­ tion and Rotary International "has In 1974 he helped set up a hospital at man is president of the Association of earned him the admiration, respect, and Waldia, in Ethiopia, with equipment University Programs in Health Adminis­ love of the entire Minnesota medical from Metropolitan Medical Center, Fair­ tration. He became the AUPHA' s first community," in the words of his Diehl view Hospital, and St. Mary's Hospital executive director in 1965 and has citation. in Rochester, among other places. "We taught surgery to the young Ethiopian steered that organization to its present In 1970, Dr. Arey sailed to North Afri­ doctors on an old operating table that position as a developer of more than 70 ca with Project Hope. He is an enthu­ Dr. Charlie Mayo used. We did about graduate-level training programs in the siastic flyer and skier, and "an alleged 375 operations in 100 days." health care field. golfer." On receiving the Diehl Award, A subendocardial infarct in 1976 The School of Nursing also honored he quoted Robert Montgomery: "If you slowed but did not stop him; in 1977 he two graduates with Outstanding achieve success, you will get applause. was off to Taiwan for six months, and in Achievement Awards at its alumni reun­ If you get applause, you will hear it. My 1980 to Honduras. Still practicing at ion on April21, 1982. Patricia A. Del­ advice concerning applause: Enjoy it, Fairview-Southdale (he was one of the man, M.N. ('57), M.P.H. ('73), is a but never quite believe it." first physicians to occupy the new com­ nursing consultant to the U.S. Depart­ Kristofer Hagen, M.D. ('42), has plex in 195 7), he has no immediate ment of Health and Human Services practiced family medicine in an unusual plans to travel . . . "but one never and has served as program director with variety of places: in this country with the knows.'' the Pan American Health Organization, Indian Health Service and in Richfield Distinguished former recipients of the in which capacity she helped to estab­ and Edina; in Bihar, India; and in Diehl Award have included Owen H. lish nursing standards throughout Latin Ethiopia, Taiwan, Honduras, and Viet­ Wangensteen, who received it in 1962, America. nam. the first year the award was bestowed; Marie L. O'Koren, R.N. ('46), is With the Santa] Mission in Bihar, east William C. Bernstein, as mentioned; dean of the School of Nursing at the of Calcutta, he opened an abandoned Reuben Berman; Russell Sather; University of Alabama. A native of hospital in 1952 with the help of a team Leonard Lang; and Eva Jane Larsen. Eveleth, Dean O'Koren established one of Minnesota nurses. They developed of the South's first doctoral programs in the hospital from 60 to 125 beds and New Alumni Slate nursing at Alabama and also developed added a nursing school. The school and New officers of the Medical Alumni an innovative off-campus "mobile class­ hospital are called Mohulpahari, "forest Society, installed at the luncheon meet­ room" technique for continuing nurs­ place," in Hindi, and its graduates now ing, are Donald Asp ('64), President; ing education. receive the highest scores in the region Jan Adams (' 72), Vice-president; and on national tests. Richard A. Carlson ('72), Secretary­ From 1964 to 1969, Dr. Hagen Treasurer. 16

Focus on Basic Science Department of Pharmacology

The Department of Pharmacology at search into cancer chemotherapy. Stud­ gical Sciences: Professor Wilcox with the University of Minnesota is a research ies on drug metabolism. toxicology. psychiatrists: and Professor Takemori is and teaching department with both a and carcinogenesis take place in the conducting a collaborative study of opi­ basic and an applied dimension. "It is laboratories of Professors M. W. Anders. oid receptors with Prof. Philip S. Por­ actually a combination,'' says Frederick Patrick E. Hanna. and Gilbert J. Man­ toghese. of the College of Pharmacy. E. Shideman. Ph. D .. M.D., Professor nering. Professor Jack W. Miller's work "But," says Professor Takemori. "our and Head of the Department. "because is in reproductive and endocrine phar­ strength is that we are independent in­ we use the techniques of the basic sci­ macology. vestigators. ences to investigate drugs. Pharmacolo­ Members of the Pharmacology De­ gy is the science of how chemical sub­ partment teach undergraduate medical Strength of the Graduate Program stances - drugs - interact wtih bio­ students- pharmacology courses are a "Dr. Shideman has people with ex­ systems. ·· required part of both the Phase A and pertise in all areas: all fields are repre­ Professor Shideman is only the third the Phase B curriculum - dental stu­ sented. That's why this Department is Head of Pharmacology since the De­ dents. nursing students. pharmacy stu­ so good for training graduate students. partment was organized, in 1913. He dents, and dental hygiene students. The first year. they rotate through four took over in 1962 from Dr. Raymond or five Ia boratories. and then they Bieter. who had headed the department choose a dissertation advisor." The since 1943. when he succeeded Dr. Ar­ Pharmacology Department has been thur D. Hirschfelder. Before Dr. Hirsch­ ranked No. 1 in the United States for its felder' s appointment, in 1913, phar­ graduate training program. macology was regarded as a branch of "In the first two years," continues physiology. uniting the fields of toxicol­ Professor Takemori. "graduate students ogy and materia medica and therapeu­ need a lot of supervision. By the third tics. year, they're almost on their own. By Among the faculty members Dr. the fourth year, they're starting to teach Shideman brought to Minnesota in his me.'' first years as Head are Professors Akira Graduates of this Department can be Takemori and Ben Zimmerman. In found heading and staffing other de­ 1964. Dr. Bernard Mirkin joined the partments of pharmacology in universi­ faculty: his primary interest is develop­ ties around the country, as well as serv­ mental pharmacology, and since 1971 ing in government and industry. he has headed the Division of Clinical Pharmacology within the Department. Clinical Pharmacology A strong neuropharmacology group F. E. Shideman, M.D., Ph.D. In addition to Dr. Mirkin, who is also has emerged within the Department. in­ Professor of Pediatrics, members of the cluding Professors Richard A. Meisch. These courses involve both lectures and Division of Clinical Pharmacology come Sheldon B. Sparber. Takemori. and laboratory work. from other departments in the medical George L. Wilcox. Professors Robert F. Undergraduate students in the Basic school, jointly supported by their clinical O'Dea and Nelson Goldberg are con­ Sciences can also take either a major or departments and by Pharmacology. ducting investigation into receptor a minor in Pharmacology. The 23 facul­ Research activity in the Division in­ mechanisms, at cellular and subcellular ty members in the department lecture in volves investigation in several different these undergraduate courses and are levels. areas: By far the largest group of investiga­ also the mentors of the 30 to 35 pre­ tors are those concerned with car­ doctoral graduate students and 15 or so - long-term study of neural tumors diovascular and renal pharmacology: post -doctoral fellows. of childhood, specifically neuroblasto­ Professors Earl W. Dunham, Thomas P. There are many examples of interdis­ ma. This project involves animal models Green. A.J. Quebbeman, Shideman. ciplinary research in the Department: as well as clinical research; Alan R. Sinaiko, and Zimmerman. Pro­ Professor Goldberg works with - treatment and causes of childhood fessor Norman E. Sladek conducts re- biochemists from the College of Biola- hypertension. Minnesota is one of the 17

world centers of this research. Many of the newest antihypertensive drugs being used to treat children were tested in this project; -atherosclerosis. Prof. Donald Hun­ ninghake has been conducting a large­ scale human study of the effectiveness of various drugs in lowering blood cholesterol and lipids; - kidney disease. including drug problems of kidney transplant patients. our understanding of basic biological anesthesia and surgery completely al­ Professor Mirkin estimates that Division processes. ters the functioning of the vascular sys­ members do "400 to 500 consultations "Unlike a biochemist, who may be tem." says Dr. Zimmerman. "You get per year" in the University of Minnesota interested in characterizing an enzyme elevated levels of renin. elevated pros­ hospitals on problems associated with by doing amino acid sequencing or de­ taglandins, especially prostacyclin. and kidney disease, including drug interac­ termining its crystalline structure. we the surgical trauma completely changes tions, immunosuppression, and the might want to know. for example. how the response of the kidney. Information day-to-day effects of drugs on kidney that enzyme mediates the effects of a is either exaggerated, or it's masked. patients; drug, or vice versa - whether it is a "Also, when the dogs are conscious, - the appropriate use of antibiotics. therapeutic agent, a drug of abuse. or a we can follow them for a relatively long Professor Mirkin describes the work pharmacological probe.'' time. We've done longitudinal studies of of the Division as "trying to provide in­ renal blood flow, blood pressure, plas­ terfaces between basic and clinical sci­ A Model of Hypertension ma renin activity, and renal vascular re­ ences." Clinical medicine has made sistance. We get a pretty fair picture of great technical advances, such as organ The place looks like a physiology the influence of hypertension on the transplantation, but "the basic biologi­ laboratory. A large, placid dog lies, fully target organ - the kidney. cal questions are still unresolved. The conscious, on a padded table, while its "Hypertension is a fascinating disease real issue is to understand how these blood pressure and renal blood flow are to study, because it is so multi­ things work." being monitored. A laboratory worker. determined. Irvine Page, who did some In the brief articles that follow, the one of Dr. Ben Zimmerman's assistants, of the early work on the renin­ Bulletin takes a look at work in three of speaks soothingly to the dog, and it angiotensin system. described it as a the Department's laboratories. As with thumps its tail on the table. 'mosaic.· We just look at one small part the other basic sciences, there is a di­ This dog. with instruments chronically of it. and we try to describe accurately versity of techniques, instruments, and implanted, is known as an animal model what we see. experimental approaches that an out­ of hypertension. Dr. Zimmerman and "The difference between what we do sider finds bewildering. But Professor his assistants have performed a mod­ here and what a renal physiologist does Sparber, a nationally recognized au­ ified Goldblatt procedure, constricting is that we're investigating drugs- drug thority on developmental and behavior­ one renal artery to produce renovascu­ effects, a whole spectrum of the drugs al effects of drugs, particularly drugs of lar hypertension, in order to examine that are used to treat this condition in abuse, describes their basic unity: what happens to the dog's own produc­ human beings, as well as a whole group "When pharmacologists use drugs as tion of the enzyme renin and the hor­ of substances that are not drugs, that we tools, we are generally aware that they mone angiotensin when the dog is given administer in order to study their effects: have a diversity of actions, selectivity antihypertensive drugs - the same naturally occurring substances like being dependent upon the appropriate drugs that are used for lowering high acetylcholine, bradykinin, and dose or concentration. Our understand­ blood pressure in human beings. angiotensin, and the adrenergic trans­ ing of the selective effects of drugs and "We use conscious dogs, because mitter. norepinephrine. how they affect physiological or bio­ when you examine these things in an "Antihypertensive drugs work in chemical processes may then advance anesthetized animaL the combination of different ways. Some are angiotensin 18

Department of Pharmacology

serendipity in this field: we often end up in the response to pain. When we inject with results that are totally contrary to substance P intrathecally, we observe our suppositions. behavior appropriate to the perception "Elevation of blood pressure seems of mild pain." to be the end-result of many different Substance P, says Dr. Wilcox. has processes. Perhaps you could say the several characteristics that make it a same about coronary artery disease. likely candidate for the role of a neuro­ But over the long term, even a rather transmitter for pain: it is contained in the small degree of hypertension seems to appropriate neurons: it is released from damage the target organs. That's what these neurons by painful stimulation: its we are looking at, in our research. injection seems to produce mild pain: "Clinicians believe that treating mild and this pain is blocked by morphine. hypertension early will avoid damage, The investigators found that in­ in the long run." And perhaps discover­ trathecal substance P caused mice to ies made on Zimmerman's dogs will bite, lick, and scratch the skin of their some day influence the drugs available abdomens, "for about a minute, as long to human beings. as the substance lasts before enzymes destroy it. After presenting these results Where Does It Hurt? at several meetings, we found that peo­ Dr. George L. Wilcox, Assistant Profes­ ple asked, 'Are you sure it's not itch?' sor of Pharmacology, directs a team of Classically, itch is regarded as a mild investigators in studies on the neuro­ form of pain. Ben Zimmerman biology of pain and itch. "I began my "That raised the question of what itch career as a neurophysiologist,'' he says. is. This question required looking at the antagonists and converting enzyme in­ "Neurophysiologists deduce function many neurotransmitters that may be in­ hibitors: some are alpha adrenergic from the electrical activity of different volved in the perception of sensation. blockers that block the actual receptor places in the brain. "Another peptide seems to be associ­ sites on vascular muscle cells. There are "But neuroscientists have come to ated with itch - a substance called neural blocking agents that block re­ realize the limitations of studying only somatostatin. When we inject somato­ lease of the neurotransmitter substance: electrical activity; brain function is highly statin intrathecally in mice, we observe and there are prostaglandin synthesis chemical. Every neuron, or nerve cell, generalized scratching of quite a differ­ inhibitors that also affect vascular con­ releases at least one and perhaps sever­ ent kind . . . and its effect is not pre­ trol. We look at all of them, in our al chemical substances called neuro­ vented by morphine. hypertensive model, and we see what transmitters. The study of the function "Now, it seems that morphine effects they produce on the renal cir­ of these neurotransmitters is in the doesn't block itch in humans: in fact, culation and on the animal as a whole. realm of pharmacology." intrathecal morphine causes itch." "We're interested in the effects on the The other members of Dr. Wilcox's Other investigators' neurophysiological whole animal. You could describe what team are Janice Hylden, a graduate stu­ studies have shown that substance P we do as pathophysiology, even though dent, and Sutaeg Hwang, M.D., a generally excites neurons in the spinal we only intervene in the renovascular psychiatrist from Korea who is taking cord, whereas somatostatin inhibits system." postdoctoral training in neuropharma­ them. "In other words, pain may be ex­ Support for the work in Dr. Zimmer­ cology. Their current project began citation of a neuron, and itch may be man's laboratory comes mainly from when Ms. Hylden wanted to investigate inhibition of the same neuron. the National Institutes of Health, the effect of substance P injected in­ "I got onto this last summer, when I although they have some industrial sup­ trathecally, directly onto the spinal cord. was stung on the hand by a yellow­ port: Marion Laboratories has funded a "We've known about substance P for jacket. Two days later, my hand itched study of alpha adrenergic blocking a long time," says Dr. Wilcox. "It's a intensely. Now, common sense tells us drugs. "Quite a basic study, obviously," material that occurs naturally in sensory that pain reverses itch; after all, that's says Dr. Zimmerman. "There's a lot of neurons, and its release may play a role what we do when we scratch an itch, we 19

Left, Janice Hylden probes the rat nervous system. Right, the Wilcox team: Hylden, Sutaeg Hwang, and George Wilcox.

produce mild pain, which stops the itch. "So as an experiment, I applied ther­ mal pain in the hope of altering the itch of the sting. I bathed my hand in water at about 60oC, too hot for my unbitten hand to stand, and it felt wonderful! The itch was gone. By the next day, the hand with the sting was swollen, be­ cause I'd scalded it ... and here's the exciting part: I never felt the pain of the scald. "So, the hypothesis reads: Pain blocks itch, and vice versa. Pain and itch are opposites. Pain, mediated perhaps by substance P, excites spinal neurons, while itch, mediated perhaps by soma­ The Chemistry of are constantly taking place in our en­ tostatin, inhibits them." Perception vironment. This project has been supported by 'The concept of receptors has been several grants, including a research A distinguished investigator in the De­ around for some time - but techniques grant from the Minnesota Medical partment Dr. Nelson Goldberg, is an were not available until recently to Foundation and funds from the Nation­ internationally known authority on cy­ prove their existence. However, many al Institute of Drug Abuse. This spring, clic nucleotide metabolism. The walls of of the new drugs you read about, called the project was awarded a three-year his office are bright with Chinese water­ agonists or antagonists, are designed research grant from Procter & Gamble's colors among the textbooks, and some­ from information that has been de­ University Exploratory Research Pro­ one has cut out a magazine cartoon veloped from this concept: The beta gram, for $119,000. showing a chef tasting a dish and say­ blockers, which have recently been About the future of the research, Dr. ing, "More Yin, less Yang.'' shown to produce such dramatic and Wilcox says, "It's hard to quantify be­ In an informal but impressively well­ beneficial effects in the treatment of car­ havior satisfactorily. 'Hard' science re­ organized conversation, Dr. Goldberg diac problems such as angina, are a quires measurements. The biting, lick­ told the Bulletin how his work connects good example. ing, scratching behavior we observe in with the more tangible clinical aspects of "In this laboratory, we work on what our mice is 'soft'; it's animal behavior, health science. lies beyond the receptor." Dr. Goldberg graded by a less than perfect human. "Some fifty years ago, A. J. Clark a occupies most of the fourth floor of "We need to measure the activity of pharmacologist, proposed the existence Lyon Laboratories. Working with him spinal neurons projecting to the brain, in of receptors or recognition sites on the are research fellow Dr. Tim Walseth, response to pain, itch, and injected sub­ outside of cells, that could recognize a associate scientist Beth Kuehn, and stances. And that is what we are propos­ hormone molecule or neurotransmitter junior scientist Susan Eide. Several ing to do.'' such as epinephrine - Adrenalin. members of the Biochemistry Depart­ These 'messenger' molecules are dis­ ment from the College of Biological Sci­ charged from certain sensing organs like ences also collaborate, specifically Prof. the brain to signal specific types of cells John Gander and senior scientist Tom that can recognize the 'message' to per­ Krick. form or not to perform the particular "We are interested in what happens function for which they were designed. after the 'messenger' molecules attach 'The recognition of the messenger to their receptor. How is the information molecule by the receptor causes a re­ transmitted from the surface into the programing of the body's functions to a cell? What are the 'effector' molecules new set of instructions that permits that actually modify the function of the accommodation to the changes that cell's internal machinery? The Goldberg team. Seated, from left: junior 20 scientist Susan Eide, Nelson Goldberg, senior scientist Tom Krick, Prof. John Gan­ der. Standing. Tim Walseth, Beth Kuehn.

Department of Pharmacology

"We already know that the message The Yin/Yang hypothesis came to the within milliseconds; but whether or not received by the receptor is transmitted attention of Chinese scientists, who this really occurs, we don't know. to a transducer. The transducer is linked have an active research effort in this "We believe this represents the long­ up to another molecule called a cyclase. area, and Dr. Goldberg was invited to sought magnification step in vision. and which amplifies the signal. In fact. the come to China and lecture to medical we are studying this system from the whole system can best be described as a school faculties. perspective of the light stimulus repre­ multi-stage amplification network. rep­ "I lived there for two months, mostly senting the hormone. In order to test resented by a cascade of enzymes that is in Shanghai and Peking. They have re­ this new concept in the retina and other capable of amplifying the signal from a cently appointed me Honorary Profes­ systems, we have developed a means of single molecule. such as epinephrine, to sor at the Shanghai Medical College. monitoring the dynamics of cGMP and more than a trillion molecules of glucose I've been invited again this fall, and I'd cAMP metabolism in intact cells. simply that are released, for example from the like very much to contribute to the de­ by substituting water containing isotopic liver, to maintain the blood sugar level velopment of Chinese medical science, oxygen for regular water in the cell in­ during fasting." but things in my laboratory are so excit­ cubation medium. This complex system of reception and ing that I'll probably have to postpone a "When the cyclic nucleotides are communication is very delicate. It can return visit for a while.'' hydrolyzed, an atom of the isotopic ox­ be affected by external stimuli as well as What is exciting in the Lyon Labora­ ygen becomes permanently trapped in by internal cellular events. Dr. Goldberg tories is that Dr. Goldberg's work with the metabolic product. We have made and his colleagues have focused on the cGMP has led to work on the chemistry the first measurements of how the cyclic basic chemical mechanisms under­ of the transduction of light by the retina nucleotide systems really behave in in­ lying the regulation of cell functions. of the eye into a neural impulse - the tact cells, and we have been astounded "Cyclic adenosine monophosphate chemistry of sensory perception. at how much more dynamic these sys­ - cAMP - plays a key role as an effec­ "We know, now, that cGMP is in­ tems are than was previously thought. tor within the cell that controls numer­ timately involved in sensory reception. "It's difficult to predict exactly how ous cellular processes. Another cyclic which we believe may represent a mod­ our basic studies of cyclic nucleotide nucleotide, cyclic guanosine el for its involvement in other cell pro­ metabolism and its involvement in con­ monophosphate or cGMP, we discov­ cesses. The problem in understanding trolling cell functions will ultimately re­ ered is also present, in all cells. We the precise biological importance of late to clinical medicine, but the poten­ believe it plays an equally important but cGMP is that the mechanism by which it tial seems to be considerable. Imbal­ opposing role: If cAMP inhibits white controls cell function has not been de­ ances in cyclic nucleotide metabolism blood cells from performing their func­ fined. A new concept we have been are believed to be the cause of many tion, for example, we find that cGMP is working on represents the antithesis of disease processes, including cancer. car­ intimately involved in promoting the the classical view, which has failed to diovascular disease, diabetes, epilepsy. complex function of these cells. cAMP come up with the answer to this impor­ asthma, and blindness. stimulates the contractility of the heart. tant problem. "Other basic studies have made cGMP inhibits it. ''Our idea is that destruction of cGMP possible the development of receptor "From these observations we formu­ by way of its hydrolysis is the important antagonists and agonists that are effec­ lated what we called the Yin/Yang aspect of its metabolism, and that this tive for the treatment of scores of dis­ hypothesis of biological regulation, a process is a means of generating pro­ orders: antibiotics. antipsychotic agents. metaphor. really for the relationship of tons, rather than merely getting rid of anticonvulsants, drugs that prevent re­ these two substances in controlling cell the cGMP, as everyone had thought. In jection of transplanted organs (see story processes. It is a concept that is con­ the case of the retina, for example, it on p. 21), and others. sonant with the theories of classical can be shown that one photon of light "I can go back to China another time. Oriental medicine, which are based on a has the potential to promote the hy­ For now, I'm involved in this work." system of complementarities." drolysis of 100,000 molecules of cGMP ~ 21

On the Campus

New Health Sciences VP responsibility for clinical research. ified candidates to President Magrath, Teaching hospitals also have traditional­ who chose Dr. Vanselow. "When someone comes into a new ly taken care of indigent patients.'' "He had experience as a dean and as situation," says Neal A. Vanselow, Born in Milwaukee, Dr. Vanselow a vice-president,"' says Dean Stauffer, M.D., the new vice-president for health studied at the University of Michigan, "and he had done a successful job of sciences at the University of Minnesota, where he received his M.D. cum laude negotiating with the Nebraska legisla­ "the first thing they have to do is listen, in 1958. He lived in Minneapolis in ture. In talking with him and seeing him rather than tell people what they're 1958-59. when he served a rotating in­ relate to people, we found him an open going to do." ternship at ''the hospital that is now person, forthright, accessible, but firm in On September 1, when Dr. Vanselow called Hennepin County Medical Cen­ his ideas. People feel comfortable with comes to the Twin Cities from Omaha, ter." then went back to Ann Arbor for him; he has a sort of Minnesota air." where he has served as Chancellor of a residency in internal medicine and a Dr. Vanselow and his wife, Mary the University of Nebraska Medical fellowship in allergy. Ellen, have two children, Julie and Center and vice-president of the Uni­ He joined the faculty of Michigan's Richard, both students at Iowa State versity, he says he plans "to do a lot of Department of Internal Medicine. then University. "You know," commented listening." Dr. Vanselow, "the year we spent in Dr. Vanselow will take over the vice­ Minneapolis was the first year we were presidency from Dr. Lyle A. French, married. I made $75 a month as an in­ who has occupied the position since it tern. My wife, who was a nurse, made was created in 1970. Dr. French told the $320. It was wonderful; we've never Board of Regents in July, 1981, that he had more money in our lives. wished to return to teaching and clinical "We're looking forward to the Minne­ work as professor of neurosurgery. sota autumn," he said. Dr. Vanselow will be the guest speaker at this year's A Challenging Position Annual Meeting of the Minnesota Medical Foundation, to be held October "From what I know," continues Dr. 27, at the Minneapolis Club. Vanselow, "all the health sciences at Minnesota are superb. Still, there will be Heart Transplant Study many challenges in this position." He states firmly that construction of the new at U of M hospital is "going to have to be the No. "No one person can .know everything 1 priority. The commitment has already there is to know about heart trans­ Neal A. Vanselow been made. plantation," says Dr. Ron Ferguson, ''Controlling health care costs will be became Head of the Department and one of the University of Minnesota's a big issue in the years to come. Here in Director of the Medical Center Office of transplant surgeons. "There's the car­ Nebraska, we're looking at ways to cut Health Professions Education and Re­ diology, the medical management, the costs, to reorganize outpatient depart­ search. In 1974, he went to the Uni­ transplant surgery itself, and the im­ ments or reassign students. Of course, versity of Arizona as a Professor of munosuppression. It is a team effort." we are only approximately half the size Medicine and Dean of the College of The University's cardiac transplanta­ of Minnesota. Medicine, and in 1977 to Nebraska as tion team will have a chance to demon­ "Still, University hospitals are going professor and chancellor. strate the success of the procedure in the to have to change. On the other hand, course of an 18-month study of heart teaching hospitals provide a lot of im­ "A Minnesota Air" transplantation, jointly sponsored by the portant functions that are not always federal Health Care Financing Adminis­ consonant with the greatest cost­ The search committee for the new Min­ tration (HCFA) and the US Public efficiency. You can't really compare nesota vice-president, headed by Lee Health Service. The study will deter­ them with other hospitals. They train D. Stauffer, Dean of the School of Pub­ mine whether the operation, first per­ students and residents; they have the lic Health, presented a list of five qual- formed 25 years ago by Dr. Christiaan 22

On the Campus

Barnard. with techniques developed at proved immunosuppression,'' says Dr. Clayton Named to NBME the University by Dr. Norman Shumway Ferguson. ''Not only are we seeing few­ (see Commencement story. p. 1 ). and er rejection episodes. but also fewer in­ Paula J. Clayton, M.D .. Professor and others. is a viable and cost -effective fections.'' Head of the Department of Psychiatry. medical procedure. Cytomegalovirus (CMV) has been a University of Minnesota Medical "We feel that heart transplantation is well publicized cause of some post-heart School, has been appointed to the no longer experimental." says Dr. John transplantation infections. ''Cyclosporin National Board of Medical Examiners (NBME). as a member of the Board's Najarian. chief of surgery. is effective against it,'· says Dr. Fergu­ Part II Psychiatry Test Committee. Minnesota is one of only six centers son. "We're seeing a markedly reduced She joins a corps of more than 100 across the country that will participate in incidence of CMV." distinguished medical educators who the study: the Medical College of Virgin­ As soon as HCFA determines the dol­ have accepted the responsibility for de­ ia. Columbia-Presbyterian Hospital in lar amount that each hospital study cen­ veloping and maintaining the NBME' s New York City: the University of Pitts­ ter will receive, the program will begin. evaluation system. burgh, the University of Arizona, and "We could start tomorrow." says Dr. Stanford University, where Dr. Shum­ Ferguson. "I think if s good to have standard way is chief of cardiovascular surgery. tests." says Dr. Clayton, "especially in are the others. Lazarow Lecturer psychiatry. The examination gives the specialty a more credible and less am­ Dr. Najarian said he expects a posi­ biguous standing than the image it tive outcome to the 18-month study. has had in the past." "Two and three years afterward, some of these patients appear perfectly A native of St. Louis. Dr. Clayton healthy." he says. Of the ten patients came to Minnesota in 1981 from the who have received heart transplants at Department of Psychiatry at Washing­ the University since 1978. five are alive ton University Medical School. where and well. "We believe this proportion she received her M.D., and where she will grow ... says Dr. Ferguson, "and that was Professor of Psychiatry and Direc­ 50 to 70% of patients will do very well.·' tor of the Adult Inpatient Service at Barnes Hospital. "With heart transplant patients," he The National Boards are universally continues. "we are looking at people recognized as indicators of professional with end-stage cardiac disease. You've Stefan S. Fajans, M.D., Professor of qualifications. Medical licensing author­ got to be realistic.'' Medicine and Head of the Division of ities in 48 of 50 states accept Board cer­ Realistically, such patients can expect Endocrinology and Metabolism at the tification without further requirements. only a year or two of painful disability University of Michigan, Ann Arbor.de­ About 80% of U.S. medical graduates before they die, unless they receive a livered the Seventh Annual Lazarow are licensed to practice medicine new heart. The costs of the procedure. Lecture on June 24. The lecture series. through National Board certification. honoring Dr. Arnold Lazarow, former which now run between $40,000 and In the words of Edithe J. Levit, M.D., Professor and Head of the Department $50,000. not including post-operative President and Director of the NBME. of Anatomy, who died in 1975, is spon­ care, must be balanced against such an "The test committees form an integral sored jointly by the Department and the unacceptable quality of life and against part of the Board's evaluation system, Minnesota Medical Foundation. the costs of frequent hospital admissions and it is through the dedicated efforts of and palliative care. Dr. Fajans, who directs the Michigan these individuals [examiners] that the The major complication of heart Diabetes Research and Training Center, Board . . . provides examinations of transplantation has been rejection of the spoke on "The Heterogeneity of Di­ high quality." implanted organ. The next most serious abetes Mellitus," presenting the current complication is infection, when patients view that diabetes is a syndrome rather are given immunosuppressant drugs to than a single disease, representing the overcome the organ rejection. ''The end-point of different pathogenetic drug cyclosporin has tremendously im- mechanisms. 23

Mellon Foundation Grant vious consequence of understanding Retirement mechanisms of reproduction is being Grace Mary Ederer. M.P.H. ('62). pro­ The University of Minnesota has re­ able to control them, either to aid infer­ fessor in the Division of Medical Tech­ ceived a three-year grant from the tility or to manage fertility." Andrew W. Mellon Foundation for a nology. Department of Laboratory project in which Dr. David Hamilton, Medicine and Pathology. retired on head of the Department of Anatomy, Faculty News June 30. 1982. after 30 years at the will study sperm cell maturation. Pro­ university. A native of Morton. Minne­ Dr. Elof G. (Gus) Nelson. assistant pro­ teins on the surface of sperm cells seem sota. Professor Ederer received her B.A. fessor of family practice and community to govern their motility as well as their in 1941 from the College of St. Cather­ health. has been named vice-president capacity to fertilize ova of the same spe­ ine. St. Paul. and served her medical for health and human services at North cies. Dr. Hamilton's investigations will technology internship at Providence Memorial Hospital in Minneapolis. He involve developing antibodies to sperm Hospital. Detroit. She came to the Uni­ will remain a part-time member of the cell surface proteins: these antibodies versity of Minnesota in 1952 as an in­ Department faculty and will continue to serve as markers and enable the investi­ structor in laboratory technology and coordinate the Behavioral Medicine cur­ gator to locate a particular protein, both progressed steadily through the riculum. where it appears on the cell surface and at academic ranks. becoming an associate what stage in the maturation process it is Professor of Medicine Athanasios professor of laboratory medicine and formed. Theologides will be the new head of pathology in 1967. A specialist in micro­ oncology at Hennepin County Medical Dr. Hamilton, a graduate of Harvard biology, at her retirement Professor Center. He remains a full-time member Ederer was Director of Bacteriology. (B.A., 1957), the University of Kansas of the Department of Medicine. (M.A., 1960), and Cambridge Universi­ Mycology. and Parasitology in the Mi­ ty (Ph.D., 1963), has studied mamma­ crobiology Laboratory of the University lian reproductive anatomy for a number of Minnesota Hospitals. Departmental Appointments of years. Until his 1981 paper, "Alpha­ Richard W. Asinger. Gary S. Francis. Lactalbumin-like activity in fluids of the In the Department of Anatomy. Dr. Paul Roger L. Gebhard. Robert P. Hebbel. male reproductive tract" (Biology of Re­ C. Letourneau was promoted from William F. Keane. Craig J. McClain. production 25:385), "it was assumed," assistant to associate professor: Martin Oken. Lance Peterson. and he says, "that alpha lactalbumin was In the Department of Biochemistry. Geza Simon from assistant to associate present only in the milk of lactating Dr. James B. Howard from associate professor: Dr. Russell V. Luepker from mothers. Now we have found that it is professor to professor: lecturer to associate professor. to con­ present in semen in animals in very high In the Department of Family Practice form to his appointment 'in the School quantities.'' and Community Health. Dr. Richard L. of Public Health: It is possible, he believes, that "this Holloway from assistant to associate In the Department of Neurology. Dr. molecule has some regulatory role in professor: Ronald E. Cranford from assistant to how the (surface) protein is assem­ In the Department of Laboratory associate professor: bled." This summer, Dr. Hamilton is Medicine and Pathology, Dr. Patricia In the Department of Otolaryngology. working on sperm cell surface proteins Ferrieri. professor of pediatrics. to pro­ Drs. Robert H. Maisel and T etsuo Mori­ with Dr. Roger Craig at the Courtauld fessor: Dr. Leo Furcht from associate zono from assistant to associate pro­ Institute of Biochemistry in London. professor to professor: Drs. Larry D. fessor: The Mellon award of $185,000 will Bowers. Lance Peterson. Richard Sib­ In the Department of Radiology, Dr. be administered by the Minnesota ley, and Michael J. Wilson from assis­ Mathis P. Frick from assistant to associ­ Medical Foundation. For the past sev­ tant to associate professor: ate professor: eral years, the Mellon Foundation, In the Department of Medicine. Dr. In the Department of Surgery. Dr. like the Ford and Rockefeller Founda­ Morrison Hodges from associate profes­ Theodor B. Grage from associate pro­ tions, has included basic study of repro­ sor to professor: Dr. Rex B. Shafer from fessor to professor and Dr. Santhat duction in its population program. associate professor of medicine and Nivatvongs from assistant to associate According to Dr. Hamilton, "the ob- radiology to professor of both: Drs. professor. 24

Honors

which students present their research course and as a member of the Neuro­ Student Achievement results. and in fall, 1981. she attended a logical Science track committee. Awards special NIH course in clinical hematolo­ The third-year student nominated for Four graduating medical students and gy. A summa cum laude graduate of outstanding achievement is Daniel D. one third-year (Phase D3) student won Stanford University, she is also a mem­ Buss. President's scholar and summa the 1982 Medical Student Achievement ber of AOA and Phi Beta Kappa. cum laude graduate of the University of Awards from the Minnesota Medical Minnesota and a member of Sigma Xi Foundation. The awards. in the amount and AOA. He has already shown ex­ of $1.000 each. recognize extraordinary traordinary ability as an investigator. achievement in medical school. in specifically in developing a blunt trauma academic and clinical work. research. animal model for studying and evaluat­ leadership. and community service. ing osteoarthritis, and his academic re­ Nadine Smith, MD. presented the cord is faultless. In addition. he has awards at a meeting of the Medical maintained an unusually high level of School Administrative Board on May participation in community affairs. serv­ 20. ing on the student grievance committee The 1982 winners were Candy and the cardiovascular course commit­ Abramson. Duluth; Thomas Bergman. tee, as well as coaching Little League Daniel Buss. and Matthew Norman. all baseball and chaperoning youth of Minneapolis; and Carole Lannon. groups. Glen Ellyn. Illinois. Students are nomi­ "I really only have two passions ... he says. "medicine and my wife. We got nated by medical school faculty, clinical Candy Abramson preceptors. other students. or col­ married this year. and she is immensely supportive - emotionally as well as leagues with a knowledge of their work. About Thomas Bergman's clinical financially." The MMF Awards and Honors Commit­ work, one of his advisors wrote. "His tee selects each year's recipients from clarity and inquiring insight served as a Buss's research in the Department of among the nominees. model even for those his seniors in ex­ Orthopedic Surgery was made possible Candy Abramson. described by her perience." His research record is also a by a fellowship from MMF. As an under­ teachers as an "outstanding young sci­ distinguished one; he received both an graduate. his three years of research in entist" who has already "made major MMF research grant and a student re­ biochemistry won the Thomas E. contributions to the medical field." has search grant from the Department of Andrews Award, and he has published done most of her work in cancer im­ Laboratory Medicine and Pathology. two papers in the biochemical literature. munology. her primary field of interest. Neurological disease has been his pri­ "My mother had cancer ... she says. ''in mary interest, although he also partici­ 1974: that sparked my interest. She's pated in research projects on endocrine doing all right now. But I want to find disorders and head trauma. He is now a out as much as I can about these dis­ resident in neurosurgery at the Universi­ eases. ty of Minnesota Medical Center. To date. Dr. Abramson has eight Dr. Bergman's academic record in publications to her credit. as principal medical school continued his excellent author or co-author, and she is currently undergraduate record. For eight straight a resident in medicine at Barnes Hospi­ years. since he first enrolled as a fresh­ tal. St. Louis. man at Princeton in 1974, he received In 1981. she won the MMF's J.T. the annually renewable Alworth Schol­ Livermore Award for outstanding re­ arship. and he was vice-president of the search in hematology. She has achieved Minnesota chapter of AOA. He served distinction outside the laboratory as his class as student representative for well: she helped to organize a seminar the Planning and Management Com­ program within the medical school. in mittee of the Phase B reproduction Thomas Bergman 25

Carole Lannon's work, both clinical ing and able to pursue student lead­ and investigative, shows "a scope and ership, community service, and depth rarely seen in a medical student," academic excellence simultaneously." according to one of her advisors. A She is a special-program pediatric resi­ summa cum laude graduate of Macales­ dent at the University of North Carolina ter College, Dr. Lannon received "out­ - Chapel Hill, where she will continue standing" evaluations throughout her to integrate her social and scientific medical school career; she coordinated commitments. the Humanistic Medicine student group, which sponsored noon seminars and Although emergency medicine is not ali-day workshops, and twice she was normally a part of the medical curricu­ voted the Lange Award by her class­ lum, Matthew Norman has distin­ mates, for extracurricular activities ben­ guished himself in this field, as a four­ efiting the class. year volunteer with the University of Between her third and fourth years, Minnesota Emergency Medical Re- she took a year off and divided the time Matthew Norman between research on lymphoid dif­ ferentiation, under Dr. Alexandra Filipo­ his undergraduate career at the College vich, and work in the Lao and Khmer of St. Thomas, where he helped to start refugee camps of Thailand, under the a successful cooperative program with aegis of the International Rescue Com­ St. Paul-Ramsey Medical Center, offer­ mittee. Her research was supported by ing paraprofessional experience for a Zagaria Fellowship, an MMF grant, undergraduates in the biological scien­ and an NIH student research grant. She ces. He is now a resident in ophthalmol­ is also an active member of Physicians ogy at the Mayo Graduate School of for Social Responsibility and has tes­ Medicine. tified before the state hearing examiner on proposed uranium exploration in Bacaner Basic Science Minnesota. Awards In the words of another advisor, Dr. Lannon's work shows that she is "will- Carole Lannon The Minnesota Medical Foundation and the Department of Biochemistry sponse Team (UMEMRT), a member were hosts at a dinner arid symposium and instructor of the National Ski Patrol, honoring the winners of the Fifth and an instructor in first aid and CPR Annual Bacaner Basic Science Awards. training for Health Sciences students. The Bacaner Awards, given through His academic record is excellent, as is MMF by Professor Marvin Bacaner of his research: he has helped to develop a the Department of Physiology in mem­ new fluorophotometric technique for ory of his parents. Jacob and Minnie evaluating retinal lesions in diabetic re­ Bacaner. are given to graduate students tinopathy. in each of the six basic science depart­ "Diabetes is the major cause of blind­ ments who have done outstanding re­ ness in young adults," he says, "and the search - one each from the Depart­ sooner we can catch it, the more effec­ ments of Anatomy, Biochemistry, tively we can prevent it. This technique Laboratory Medicine and Pathology may lead to earlier detection: I hope [Pathobiology], Microbiology, Pharma­ so." cology. and Physiology. Dr. Norman's unusual dedication and On Monday night, May 17, at dinner Daniel Buss breadth of interest were evident during in the Minnesota Alumni Club, citations 26

Honors

and the $500 awards were given to the AOA Scholarship six winners. and at the two-part sympo­ sium. given Monday afternoon and On his wife's birthday. Phase A Tuesday morning. they presented their (freshman) medical student Jeff Robin­ papers. John A. Dani. Department of son found "a nice bond envelope in the Physiology. spoke on "Water and Ion maiL with a hand-typed address." He Permeability Properties of the Gramici­ wondered. he says. "if I won anything." din Channel... Randolph C. Steer. of That letter brought the news that he the Pathobiology graduate program of had indeed won something: the $1.000 the Department of Laboratory Medicine scholarship given annually to an out­ and Pathology. presented "Phos­ standing medical student by the Minne­ phoprotein Metabolism in the Nuclear sota Medical Foundation. with funds Envelope... Clifford J. Unkefer. Bio­ from medical honor society Alpha Ome­ chemistry. presented his work on "The ga Alpha. "A nice present for CaroL" he Carbon-13 and Phosphorus-31 NMR says. "and a terrific surprise for me.·· Spectroscopy of the 5-0-B-D­ A graduate of Highland Park High Galactofuranosyl-containing Gly­ School in Saint PauL Jeff did his under­ copeptide from Penicillium charlesii." graduate work at Washington Universi­ From the Anatomy Department. ty. Saint Louis, where he majored in Dana E. Johnson presented the results physics and biology. Returning to Min- of his work on "The Streptozoticin­ Jeff Robinson Nicotinamide-induced Rat Islet Adeno­ ma: Characterization of in vitro Proinsu­ M. B. Peterson Award nesota for medical school, he entered lin and Insulin Synthesis in Whole the university in Fall. 1981. and almost Tumor Tissue and Tumor Derived Cell­ The first Mary Bizal Peterson Memo­ immediately became active in a letter­ Free Systems." Pancras C. Wong. of rial Award. for a graduating medical stu­ writing campaign sponsored by the the Department of Pharmacology. dent who has chosen a residency in American Association of Medical Col­ spoke on "The Roles of the Renin­ neurology at the University of Minneso­ leges. protesting cuts in public aid to Angiotensin System and Renal Prostag­ ta Health Sciences Center. was medical education and the substitution landins in the Control of Blood Pressure awarded to Donald T Starzinski of St. of the high-interest Health Education and Renal Blood Flow": and Paul Paul. Administration Loan (HEAL) program. Orndorff. from the Department of Mic­ Dr. Starzinski, who earned a Ph.D. in "If costs keep going up and aid keeps robiology. read "Cell Surface Proteins Psychopharmacology before entering going down," he says, "soon the only and Development in Myxococcus medical schooL wrote. "As a psycholo­ people who will be able to become doc­ xanthus. ·· gy undergraduate. I became interested tors will be the rich. We'll be creating a Dr. H. P. C. Hogenkamp. Professor in the neurological correlates of be­ rigid class system.'' Jeff and Phase B and Head of the Department of Bio­ havior and as a graduate student, student Mark Schmalz. also active in the chemistry. chaired the symposium. The neuropharmacology fascinated me. letter-writing campaign, told their story six basic science departments. each of Medical school has led to an apprecia­ on a local television show in May. 1982. which selects its own recipient for the tion of clinical applications of the neuro­ Even with this extracurricular activity. logical sciences. I expect to see exciting Bacaner Award. host the annual sym­ Jeff was able to maintain outstanding posium in rotation. new horizons in Neurology related to grades. He and his wife are caretakers in advances in Neuropharmacology. The Bacaner Basic Science Awards their apartment building: she works full are intended to stimulate "creative re­ Dr. Edward Noh! Peterson ('24). of time in retail menswear, and Jeff some­ search" in the basic sciences. "The en­ Virginia. Minnesota. established this times pinch-hits for her. Marriage couragement of young investigators." annual award through the Minnesota "makes things a bit easier," he says. Dr. Bacaner has said. "is to my thinking Medical Foundation in memory of his "The other person can pick up the slack the most important contribution anyone wife. Mary Bizal Peterson. - financially and emotionally." can make to assure the fruitful future." Jeff has many good things to say 27

about the Medical School, especially the Carolyn Borow Wins administration. "People are really coop­ Burke Award erative. They're wonderful about cut­ ting red tape. Somehow I got two ID Carolyn J. Borow, M.D., a resident at The Department of numbers at one point, and the folks in Fairview-St. Mary's Smiley's Point Clin­ Family Practice and Community Health the office smoothed it out for me. They ic, has won the 1982 Leonard P. Burke cordially invites you to a know how hard we work.'' Memorial Award for extraordinary He looks forward to Phase B and its achievement by a Resident in Family rotating clerkships. "We've learned to Practice and Community Health at the take histories and do physicals, but University. for that's not enough. I want to see some At a banquet honoring 43 new Fami­ sick patients and learn from them." Jeff ly Practice Residency Training Program ~R]irJU]1111f7.G P\ESIOB~IJ?S has not chosen a specialty, but "almost graduates, Dr. Borow was presented certainly clinical medicine." with a certificate and a check for $750 ~ Jeff will keep on writing letters, and from the Minnesota Medical Founda­ the AOA scholarship will certainly come tion. Dr. Edward W. Ciriacy, Professor ~ in handy: "It'll be more difficult to work and Head of the Department of Family as the curriculum becomes more de­ Practice and Community Health, pre­ uof m}ilfurnQi ~rub manding. I'd never really known about sided at the banquet, for nearly 200 AOA before," he says. "But if they do guests, in the University of Minnesota good work like this, I'm all for them. I Alumni Club on June 2. A Minneapolis native, Dr. Borow hope to belong, someday." Dr. Borow has shown an unusual in­ attended the University of Minnesota as terest in the community health needs of an undergraduate (B.A., summa cum the mentally ill. Her interest in psycholo­ laude, 1973) and Boston University 1982 Barnum Fellows gy led her, in her second year of resi­ School of Medicine, where she was dency, to form the Minnesota Archetyp­ awarded a certificate of recognition as The Department of Biochemistry has al Study Center. MASC is an organiza­ the best student in community medi­ announced the winners of Cyrus P. Bar­ tion that refers patients to free or low­ cine, 1978. She is a member of Physi­ num, Jr., Teaching Fellowships for cost sources of therapy and to classes cians for Social Responsibility, the Twin 1982: teaching assistants Richard Mik­ and community activities that address Cities C. G. Jung Association, and the sicek and Luann P. Rosenthal each re­ psychological needs. Sierra Club. ceived $400 cash prizes and certificates Seeing a lack of facilities available in The Leonard P. Burke Memorial through the Minnesota Medical Found­ the community for severely disturbed Award was established by his family on ation for their exceptional work during patients, Dr. Borow worked as a volun­ Dr. Burke's death, in 1979, after nearly the 1981-82 academic year. teer with Hennepin County mental 50 years of family practice in Verona, Miksicek, a graduate of Northwestern health personnel and others to establish N.J., to reflect his high ideals of com­ University, is completing his graduate a residential treatment center for chroni­ munity service by a family physician. He work in Dr. Howard C. Towle's labora­ cally mentally ill young adults, where in­ was a 1931 graduate of the University tory. He plans to go to Heidelberg for tensive psychological therapy could be of Minnesota Medical School. his post-doctoral work. combined with training in independent Dr. Borow has extended her three­ Rosenthal received her undergradu­ living skills. year residency into four years, as a re­ ate training at the Universite de Paris, After more than a year of hard work, sult of her commitment to Janus. In VII. She is working as a graduate stu­ such a facility, called Janus, opened in their nomination, her colleagues said, dent with Prof. James W. Bodley. March, 1982, under the joint aegis of "We believe her unique approach of The Barnum Traching Fellowship in Hennepin County, MASC, and the Wil­ combining the efforts of allopathic Biochemistry is awarded annually in lows Convalescent Centers. Dr. Borow medical methodology with a basic memory of Cyrus Paine Barnum, Jr., a developed the family therapy compo­ psychological approach to care and distinguished member of the biochemis­ nent of the treatment facility as her treatment of a difficult group of patients try faculty who died in 1965. Community Health rotation. is to be highly commended." 28

Honors

New AOA Members New AOA members of the Class of Members of the Class of 1983: At ceremonies held April 13. 1982 at 1982: Jeffrey L. Adams. Eveleth; Susan Robert E. Anderson, Aberdeen, SO; the Town and Country Club, St. Paul, D. Adamson, Thief River Falls; Dana L. Neil M. Bealka, Stillwater; William D. medical honorary society Alpha Omega Battles, Minneapolis; Jay C. Erie, Beyer. South St. Paul; Dawn M. Blom­ Alpha announced the election of 45 Crookston; Karen M. Gosen, Brainerd; gren, Hopkins; Denise L. Bonde, Fari­ new members, 22 of them graduating Paul E. Havel, Minneapolis; Stuart B. bault; Daniel D. Buss, Claremont; John seniors in the University of Minnesota Johnson, Bloomington; Danny B. W. Crump, Glen Ellyn, IL; Maryanna Medical School and the rest, members Lange, Harmony; Michael A. Maddaus, Destro, Rochester; David C. Eitrheim, of the Class of 1983. Minneapolis; Douglas J. McDonald, Rochester; Nancy C. Elder, Blooming­ Peter Dehne!, M.D., '82. president of Albert Lea; Gregory P. Melcher, Buffa­ ton; William A. Fintel, Minneapolis; Cin­ the Alpha (Minnesota) chapter, lo; William D. Morin, White Bear Lake· dy M. Howe, Minneapolis; Mary D. announced the donation of a $1,000 Susan K. Nelson, Red Wing; David C Johnson, Sidney, MT; Julianne E. Kos­ scholarship award for academic excel­ Nomeland, Osakis; David C. Primrose, ki, Babbitt: Theodore J. Loftness. lence to the Minnesota Medical Founda­ Bloomington; Kenneth S. Rholl, Gold­ Gibbon; Cynthia L. Lystad, St. Paul; tion. (See story on p. 26.) Drs. Joyce L. en Valley; Graham D. Ritts, Rochester; Richard J. O'Neill, Duluth; Bruce E. Funke, Assistant Professor of Medicine Elizabeth R. Seaquist, Minneapolis; Rolf Shapiro, Minneapolis; David L. Slater, and Assistant Director of Boynton N. Sigford, St. Paul; Valerie K. Ulstad, St. Paul; Marilyn A. Thompson, Val­ Health Service, and W. Albert Sullivan, Edina; Craig A. Walden, Balaton; and ders, WI; Kevin W. Treacy, St. Paul: Associate Dean of the Medical SchooL Roberta L. Zimmerman, White Bear Jeffrey N. Weitzel, Brooklyn Center; were guests at the banquet, which was Lake. and John L. Zenk, Olivia. attended by 125.

The 50 Club: 1982 Edition Leonard A. Lang, Edina Twenty-two alumni of the Medical Alex G. Berger, Minneapolis Russell C. Lindgren, Edina School were among those physicians Alice H. Fuller, Minneapolis Burtis J. Mears, St. Paul honored by the Minnesota Medical Joseph L. Garten, Minneapolis Stephen D. Mills, Rochester Association on May 27, 1982 for 50 John A. Haugen, Minneapolis Elisabeth M. Murray. Minneapolis years of medical practice. Walter K. Haven, Minneapolis Maynard C. Nelson, Minneapolis Recognized as new members of Raymond P. Hawkinson, Minneapolis 0. L. Norman Nelson, Minneapolis MMA's Fifty Club were these senior Samuel M. Herman, West St. Paul Albert E. Ritt, St. Paul alumni, most of whom were part of the Elmer M. Hill, Minneapolis William G. Rogne, Spring Grove Class of 1932: Llewellyn P. Howell, Rochester Reinhardt L. Schmidtke, Bloomington Willard M. Akins, Red Wing Alex A. Kugler, St. Paul Nels N. Sonnesyn, Tampa, Florida

Continuing Education Aug. 5-6, Recognizing and Resolving Sept. 13-17, Radiology/82: Skeletal Oct. 6-7, A Symposium: The Clinical Chemical Abuse Problems, Hazelden Radiology Including the Spine, Willey Use of Exercise Testing, Prescription Foundation. Center City, MN Hall, U of M, Minneapolis and Training, North Memorial Medical Sept. 23-25, Fifth Annual Trauma Center, Minneapolis Sept. 1-3, Annual Autumn Seminar: Seminar. Hennepin County Medical Oct. 20-23, Principles of Colon and Obstetrics & Gynecology, Hyatt Regen­ Center, Minneapolis cy, Minneapolis Rectal Surgery, Mayo Memorial Au­ Sept. 24-25, Endourology: Percu­ ditorium. Minneapolis Sept. 9-10, Topics in Geriatric Medi­ taneous Access to the Urinary Tract, cine: Endocrinology and the Elderly. Health Sciences Unit A, U of M, Min­ For further information, call Continuing Willey HalL U of M, Minneapolis neapolis Medical Education, (612) 373-8012 29

Medical Foundation

Small Research Grants (TCGF)-Dependent Responses and the Expression of the TCGF Receptor''; Small research grants totalling $35,000 were awarded by the Minnesota Medi­ R.V. Clayman, Assistant Professor of cal Foundation in fiscal 1981-82: Urological Surgery, received $3,692 for V.S. Seybold, Assistant Professor of work on "Cholesterol Biosynthesis in Anatomy, received $3,490 for a project Human Renal Malignancy: In vivo entitled "Receptor Autoradiography us­ Studies using Athymic Mice." ing a Darkfield Stereomicroscope"; K.W. Adolph, Assistant Professor of Board Report Biochemistry, received $3,692 to in­ At their Spring Board meeting, the vestigate "Nonhistone Proteins and Trustees of the Minnesota Medical HeLa Chromosome Structure"; Foundation set a fund-raising goal of J.J. O'Leary, Assistant Professor, $3.5 million for fiscal year 1983 and and J. Donhowe, Instructor of Labora­ approved a $3.145 million program of tory Medicine, received $3,692 to pur­ service to the University's two medical sue their work on "Mechanism of schools at Minneapolis and Duluth. Altered T and B Lymphocyte Function An important part of this program will in Aging Man"; be $500,000 in loans to medical stu­ K.S. Kleiman, Post-doctoral Fellow dents. Seven new faculty research pro­ in Medicine, also received $3,692 to posals worth $36,450 and two student perform "In vitro Studies of Human proposals for $1.800, making a total of Monocyte T Cell Interactions in Uremic $38,250 in small grants, were approved Patients"; by the Board. P.K. Peterson, Associate Professor of Special Grants were approved which Medicine, received $3,100 to study will provide $15,000 to fund a clinical "Receptors of Human Alveolar Mac­ research project in radiation therapy rophages and Polymorphonuclear and $5,380 for three other University Leukocytes for C5a and C3b"; projects in research and education. Spe­ cial grants often have a timely urgency, J.D. Taurog, Assistant Professor of perhaps rescuing an investigator when Medicine, received $3,500 for "Studies other support may have been suddenly of the Cellular Basis of Adjuvant reduced or canceled in federal budget Arthritis"; cutbacks. The new MMF budget in­ N.J. Vogelzang, Assistant Professor cludes $350.000 for the Research of Medicine, received $3,692 for a proj­ Grants Program. ect on "Human Germ Cell Tumor The 1982 Annual Meeting of the Xenografts Maintained in Thymus­ Foundation will be held Oct. 27 at the Deficient (Nude/Nude) Mice: Morphol­ Minneapolis Club, at 6:30p.m. Dr. Neal ogical and Biochemical Studies"; Vanselow. new Vice-President for J.M. Pries, Assistant Professor of Health Sciences at the University, will Medicine, received $3,350 to study be the guest speaker. "Canalicular Membrane Permeability in Mechanical Obstruction of the Liver''; R.K. Fidelus-Gort, Postdoctoral Associate, and R. Ferguson, Assistant Professor of Surgery, received $3,100 to perform studies on "The Effect of Cyclosporin A on T Cell Growth Factor 30

Focus on Alumni Dr. Charlie Sheppard

Dr. Charles Sheppard. Class of 1935. counseling sessions every evening. I'd gated. One of the first things we did was has combined several professional never had any training in psychiatry. but to mix them up. It was decided to mix careers in a single lifetime and is still what I was doing was really psychiatry. them by county, rather than by sex or going strong. Dr. Sheppard will retire "So I sold my practice and came severity of illness, and we saw imme­ from his current post as Medical Direc­ down to work at St. Peter State Hospi­ diate improvement! The women began tor of the Minnesota Security Hospital. tal." He laughs. "In those days- still. to to take more care with their appear­ St. Peter. in September. some extent - they had difficulty get­ ance. and so did the men. Their social In his 18 years of public service in St. ting good doctors. Often people came interaction improved. The more closely Peter. Dr. Sheppard has pushed for to the hospital after a scandal - drug the hospital resembled normal life. the change - for new buildings, for more addiction. malpractice, or a crime. I re­ less crazy the patients acted. treatment. and for a generally more member one of the nurses asking me. "We improved the hospital, too - humane attitude toward the residents of 'Tell me. doctor, what did you do. to pictures on the walls. flowers on the all three state hospitals in St. Peter. have to come here?''' tables. We started a dress code. It was Charlie Sheppard came to St. Peter Dr. Sheppard brought the touch of a very simple: clothes instead of nothing. State Hospital in 1964 as a hospital doc­ family physician into the sordid world of But it worked. There are more streakers tor. He became assistant medical direc­ the state mental hospitals. Also. on the outside, now. than there are on tor for both the State Hospital and the although he would never say it, he the inside." Minnesota Security Hospital in 1969: brought the dedication of a professional Minnesota State Security Hospital then he was appointed Medical Direc­ who prefers to use his training and au­ formerly was called the Hospital for tor of the Security Hospital, a post he thority in public service. and forgo the the Criminal Insane. That phrase has has held ever since. Before coming to material rewards of private practice. just about passed out of the language. St. Peter. he had been a successful solo "It was just like you read about: the as psychiatry and criminal justice studies general practitioner in Hutchinson. back wards were full of forgotten peo­ have evolved toward a different view of Minnesota. for 27 years. What led him ple. Being sent to St. Peter was like a life guilt. responsibility. and punishment. to make such a change? sentence. Patients received little help. Since 1963, the emphasis at the State "As a GP. I found that more and and their cases were almost never re­ Security Hospital has been on treat­ more of my time was taken up with viewed. One floor was full of bedridden ment, rather than incarceration. counseling my patients. It got so I never old women. "The psychotropic drugs made the saw my family. I had to schedule "The men and women were segre- single biggest difference in the care of

Old St. Peter State Hospital, Main building 31

"The back wards were full of forgotten people. Being sent to St. Peter was like a life sentence."

the mentally ill," says Dr. Sheppard, Also, I thought maybe having the judge state Independent-Republican politics "whether or not they are criminals. on the panel who sentenced them was for many years; Senator Rudy Bosch­ What used to be called criminal insan­ prejudicial. witz calls her his "mentor." ity is now regarded in two aspects: one "So the requirement was changed; is that the person is mentally disturbed it's still a three-person panel, but "Retiring on the but able to know that what s/he did one is a lawyer, one is a psychologist instalment plan" was wrong, and the second is those and the other is usually a judge, and it's cases where the crime was part of a not the original judge. They usually After such an active professional life - delusional system. reach a decision within 30 days.'' or two - does retirement seem a dull "It's in the second type that you get Was it difficult for Dr. Sheppard to prospect to Dr. Sheppard? "Not at all. a verdict of not guilty by reason of in­ involve himself in the politics of mental I've tried to take my father's advice. He sanity. That's Rule 20.02 of the Rules of illness and custodial care? "No; I've was an 1891 graduate of the Univer­ Criminal Procedure. That began to be always been very interested in politics. sity of Minnesota Medical School, and used in 1975. The Hospital Commit­ Back in 1939, when I first joined the he told me, 'Retire on the instalment ment Act was revised, under Doug Minnesota Medical Association, I was plan.' I've always taken a month's va­ Head in 1967, and now it's being re­ told it was run by an oligarchy. The cation, all in a lump. At first, so I could vamped again." Mcleod County Medical Society sent be with my family while they were Dr. Sheppard himself has had some me down to the convention as a dele­ growing up, and then so I could have influence on the redrafting of laws deal­ gate - not everybody's interested, the experience of organizing my lei­ ing with the mentally ill and dangerous you know- and I walked in and in due sure time - retiring by stages. patient. "When people sentenced to time, asked, 'Who runs this organiza­ "I have all sorts of plans, but do not St. Peter came up for review, it used tion?' Ultimately. I was asked. 'How plan to leave le Sueur. We love this old to be that there was a three-judge panel, would you like to run for vice-speaker house we live in, which was built by one including the judge that sentenced them of the House of Delegates?' of the founders of Green Giant. I plan to and two nearby judges. They took their "After that I was Speaker for 11 do some consulting and some court time about reaching a decision; some­ years, and then in 1967 they elected me work, but otherwise plan to do pretty times six to eleven months would go President." Mrs. Sheppard also has much as I please. I hope to go back to by between the hearing and the deci­ a great interest in politics. She was ac­ take some music lessons, learn Spanish sion. This was very unfair to the patient. tive in Mcleod County, District 2, and and brush up on my German, as well as

In 1964, when Dr. Charlie Sheppard came to St. Peter State Hospital, it housed between 1,400 and 1,500 pa­ tients, many of them in a three-story building called "the Flats," which had been built about 1866. "The further back and the higher up, the worse you were," he remembers. "My introduction to Upper Flat 3 came on my first day: a schizophrenic girl of 14 or 15 was huddled, naked, in the corner of a locked room. When the attendant opened the door to bring her lunch, she sprang up and ran past us out the door, knocking the tray of food all over us. She ran onto the porch and cowered in a corner there. "I heard from her, just the other month. She has been ou.t for years. She'll always be schizophrenic, but she does all right on medication." 32

"I'm glad I will have had these three months in the new building ... "

taking in a lot of plays and concerts." they had a mental illness. of course. but Dr. Sheppard is a dedicated jazz pia­ I never feared for my safety. I never In one of Dr. Charlie Sheppard's nist, who enjoys the classical repertory as really was attacked. There was one guy other lives, when he was a family physi­ welL and a passionate photographer. - luckily he had a guard on either side cian in Hutchinson, Minnesota, he grew He has taken moving and still pictures - he reached out and choked me. The a beard to help the town celebrate its on every trip, including seven trips guards stopped him. And I didn't punish Centennial in 1955, "when beards abroad. The Sheppards have visited him: we went over to a corner of the were absolutely a no-no - for any­ Russia and China, as well as most of ward and talked about why he did that. body!" To warn his patients of the the countries of Europe. on their four why he choked me. We got to be good change in their family doctor's appear­ People-to-People International travel friends.·· ance, he wrote these verses and posted missions, and they have also traveled There is a full-time psychiatrist on the them on his office door: abroad on their own. visiting their staff, now. "First time ever'" crows Dr. Let all who come into this office be­ many friends in foreign countries. Sheppard- and the new Medical Direc­ ware! "We were able to organize and de­ tor will be a psychiatrist. Dr. Brian Gott­ The Doctor has covered his face with velop contacts with physicians in every lieb. "I'm sure the hospital will be in hair- country we visited." good hands. And I'm very glad that I The "centennial bug" has bit him at Dr. and Mrs. Sheppard have two will have had these three months in the last, grown children, and their grandchildren new building. It would have been hard So please forgive this trip into the come to spend some time with them to leave, otherwise." past. every summer. About 150 patients moved up the hill All Docs in that long-forgotten day So retirement is merely the next chal­ to the new facility in June, and almost Adorned their faces with species of lenge in a life that has been filled with 200 staff members. Spread over three hay. challenges. He has switched from pri­ acres. the new hospital cost $9.5 mil­ So come, guys, join in vate practice to public service; from lion. 'Tve written to the welfare com­ To shave now is a sin family medicine to administration of a missioner and asked permission to push And see what you can grow on your large institution; from family practice to the plunger when they blow the old chinny-chin-chin! a population of mentally ill and often place up." says Dr. Sheppard, with a dangerous offenders. straight face. "Seems to me it's the least "I was never afraid for myself; I knew they could do."

New St. Peter State Hospital campus Alumni Notes 33 30s Harold G. Scheie, M.D. ('35), D.Sc. 50s Guttman conducted a two-week course ('40), was honored by the Philadelphia at the Peking Medical College for 67 City Council, on May 13, 1982. Born Dale D. Lindholm ('57) has been in the physicians, who came from 25 of Chi­ on a farm near Warren, Minnesota, Dr. private practice of nephrology and inter­ na's 30 provinces. sponsored by the Scheie put himself through medical nal medicine since 1979, with offices in ministry of public health. He also visited school during the Depression and be­ Scranton and Moscow, PA. He serves and lectured at medical schools in Xian came the first resident in ophthalmology on the faculty of the Scranton-Temple and Shanghai. at the University of Pennsylvania University Internal Medicine Residency His wife, Dagmar, accompanied him, School of Medicine. He is the founder Program and is a member of the Amer­ and she lectured at the three medical of the Scheie Eye Institute, Phil­ ican Society of Nephrology and the schools to the faculties of the depart­ adelphia, which houses the Depart­ American Society for Artificial Internal ments of English, on the subject of mod­ ment of Ophthalmology and is part of Organs. Dr. Lindholm has more than 40 ern methods of second language in­ the University of Pennsylvania Medical publications, mostly in the areas of ure­ struction. On their way back to Canada, Center. Members of the Philadelphia mia disorders. dialysis problems, the Guttmans stopped in Paris, where City Council presented him with an biocompatibility of synthetic materials, Dr. Guttman was an invited speaker at a embossed copy of their resolution citing and urinary microscopy. He and his symposium honoring Prof. Jean Ham­ his "contribution to the welfare of the wife, Dolores, have two children: Cyndi. burger, "the father of nephrology" in people of Philadelphia and the world 16, a high school junior, and Ron. 23, a France and Europe. and his accomplishments in the field of graduate of the University of Scranton ophthalmology.'' who is in Baptist seminary training. Harold J. Hofstrand, M.D. ('69), Ph.D. (Anatomy, '71), has been named direc­ 40s tor of emergency services at St. Paul Children's Hospital. He served a res­ Philip Y. Paterson ('47), a microbiol­ idency in pediatrics at the University of ogist, neuroimmunologist, and special­ Colorado Medical School and was an ist in infectious diseases, who is current­ NIH Fellow at the National Cancer Insti­ ly Head of the Department of Micro­ tute, Bethesda, for two years. Dr. and biology-Immunology at Northwestern Mrs. Hofstrand live in St. Paul and have University Medical and Dental Schools, two daughters, both of whom attend Chicago, has been named the first Guy Carleton College in Northfield. and Anne Youmans Professor of Micro­ biology-Immunology. The Youmans professorship honors Dr. Guy P. You­ Vincent R. Hunt ('60), chief of the de­ mans, professor emeritus and former partment of family practice at St. Paul­ department chair in microbiology at Ramsey Medical Center, recently Northwestern, and his wife, Dr. Anne helped to develop the first family prac­ Youmans, who served as his research tice residencies in Bahrain and the associate for more than 30 years. American University in Beirut. After Dr. Paterson came to Northwestern in spending a one-year sabbatical in the 1965 as chief of the infectious diseases Middle East, Dr. Hunt was asked to re­ section. In 1975, he was named to the turn to Bahrain and Lebanon periodi­ department chair in microbiology­ cally to help guide the program. immunology. Dale D. Lindholm The author of nearly 200 scientific Ross Olson ('67) has completed a term publications, Dr. Paterson serves on the George Skaff ('59) finishes his term this of missionary service and is now practic­ editorial boards of eight journals and is summer as chief of the medical staff at ing pediatrics with Group Health, Inc., associate editor of the Journal of Infec­ Kaweah Delta Hospital, Visalia, Califor­ in the Twin Cities. He finished pediatrics tious Diseases. nia. Two other Minnesotans serve with training during a two-year furlough him there: Tom Johnson, executive here. Wife Karin and family are relo­ Troy G. Rollins ('46), clinical professor director, and Judith Berg, M. N., director cated in Minnesota after several years of dermatology at Oregon Health Scien­ of nursing. spent in Hong Kong. ces University, Eugene, was honored by the Oregon Alumni Association with a meritorious achievement award for out­ 60s 70s standing contributions to the School of Ron Guttman ('61 ). professor of medi­ William H. Reid (' 70) is currently Medicine, at the Sumner Memorial Lec­ cine at McGill University and Director of associate professor of psychiatry and tureship Meeting in the spring of 1982. the Royal Victoria Hospital Transplant clinical research coordinator of the Ne­ Service in Montreal, recently returned braska Psychiatric Institute, University from a month-long visit to China as a of Nebraska College of Medicine, consultant for the World Health Organ­ Omaha. His sixth book, Violence in ization. Under the auspices of a United Medical Facilities, co-edited with John Nations Development Program. Dr. Lion, will be published this summer. 34

In Memoriam

John G. Freeman ('44). former medi­ Orville J. Johnson ('28) died on March cal director of two California state hos­ 12, 1982, in Edina. He was retired from pitals, died on Sept. 30. 1981. After in­ the practice of psychiatry. terning at Miller Hospital in St. Paul. Dr. Freeman entered Mayo Graduate John M. Leonard ('64) died on April3. School of Medicine in 1944 as a fellow 1982. at the age of 42. while in Hawaii. in neurology and psychiatry, served in His death was caused by a heart attack. the Army. and later practiced in Minne­ sota, Nebraska, and Montana before Daniel A. MacDonald ('09), for many settling in California. years associated with Lutheran Dea­ coness Hospital in Minneapolis. at one David Gaviser ('37). director of surgical time chief of surgery there, and since education at Mt. Sinai Hospital in Min­ 1967 honorary president of its medical neapolis and longtime Minneapolis and surgical staffs, died after a long ill­ surgeon, died on April 12. 1982. Survi­ ness in the hospitaL now called Fairview vors include his wife, daughter, and son. Deaconess. on May 4. 1982, at the age Dr. James Gaviser ('68). a Minneapolis of 95. Dr. MacDonald served as first plastic surgeon. lieutenant in the Army Medical Corps during World War I. He was among the Esther M. Greisheimer ('23). who oldest living graduates of the Medical taught physiology at the University of School. Minnesota Medical School when Elias Potter Lyon was its Dean, died on Donald C. MacKinnon ('32) died in March 9. 1982, in Rydal Park, Pennsyl­ May. 1982, in Naples. Florida, where he vania, at the age of 90. was retired from the practice of general A Pennsylvania native, Dr. Greis­ surgery. He had been active in the Min­ heimer attended college at the Uni­ nesota Medical Association during his versity of Ohio and received her B.S.: professional career in Minneapolis. she earned an M.S. from Clark Uni­ versity, and a Ph. D. in physiology from Gerald T. Mullin, Sr., powerful advo­ the University of Chicago before cate of the University of Minnesota in coming to medical school at Minnesota. the state legislature and past president She became professor of physiology of Minnegasco, died on April 28, 1982. and anesthesiology at Women's Medi­ He served 27 years in the legislature cal College in Philadelphia in 1935 and and was a major influence on the joined the faculty ofTemple University's Medical School's building program. in­ School of Medicine in 1944. cluding construction of the Mayo build­ Dr. Greisheimer wrote approximately ing in the early 1950s. In 1957. he was 150 contributions to the professional given the first Regents' Award bestowed literature and in 1972 co-authored Phy­ by the University for his tireless support. siology and Anatomy with another which included fund-raising for the Min­ Temple professor: the textbook is now nesota Medical Foundation. He is sur­ in its ninth printing. In 1980, she was vived by his wife, Ruth: two daughters: elected to the Ohio Women's Hall of and two sons, one of them, Dr. Gerald Fame. She was active in many profes­ T. Mullin, Jr. ('58). a Minneapolis sional and honorary societies, and an rheumatologist. Esther M. Greisheimer Memorial Fund has been established to provide finan­ Wallace I. Nelson ('27), a general cial aid for women medical students at surgeon, died on May 11, 1982. He was Temple University School of Medicine. still serving on the staffs of Eitel Hospital 35

and the Nicollet Clinic, Minneapolis, at George E. Williams, Assistant Dean for the time of his death. Student Affairs and Admissions at the University of Minnesota Medical Paul R. (Dick) Pedersen (' 66) was School, died on March 31. 1982. at the killed in a traffic accident near Minne­ age of 61. after 27 years of service to apolis on April 26, 1982, at the age of the University. A psychiatrist who en­ 41. An internist, Dr. Pedersen was a joyed close personal relationships with member of a group practice in Mound, both students and colleagues, Dr. Wil­ Minnesota, and he also saw patients in liams early recognized the need for on­ Waconia and at the Masonic Home in campus counseling services, and he Bloomington. founded a student-support program in 1960. In the 1970s, he helped to launch Abraham B. Rosenfield ('24) died on the Program in Death Education and May 11, 1982, at the age of 84. He was Research at the university. and he past director of special services of the served on its board of directors until his Minnesota State Board of Health and a death. major (retired) in the U.S. Army Medical A native of Fenimore, Wisconsin. Dr. Corps and had been an important figure Williams attended St. Louis University in Minnesota public health circles for School of Medicine and served his res­ many years. idency at the V.A. and University Hos­ pitals in Minneapolis. From 1946 to Margaret L. Stevenson (' 42) died on 1948. he served as captain in the U.S. July 31, 1981, in Alhambra, California, Medical Corps. of cancer. She had practiced obstetrics Dr. Williams first became involved in and gynecology in Alhambra from 1948 public health in 1950. when he estab­ until her illness necessitated the closing lished the Zumbro Valley Mental Health of her office in 1972. center in Rochester, Minnesota. and also was a consultant in psychiatry at Rodney F. Sturley ('37), former clinical the Mayo Clinic. specializing in child de­ associate professor of obstetrics and velopment. In 1955, he was appointed gynecology in the Medical School, died associate professor in the Medical on March 15, 1982, in Sun Valley, Ida­ George E. Williams School jointly in the Department of ho, at the age of 68. He had practiced 1920-1982 obstetrics and gynecology in St. Paul for Psychiatry and the School of Public many years. Health. Throughout his involvement on cam­ Bertram L. Trelstad ('32) died on May pus, Dr. Williams also maintained a 18. 1982, in Salem, Oregon, at the age practice in downtown ·Minneapolis of 77. Born in Menomonie, Wisconsin, where, among other patients, he coun­ he graduated from St. Olaf College in seled and treated many members of Northfield, then taught high school sci­ Catholic religious orders. A consultant ence before studying medicine. He to Catholic Charities. he supervised practiced family medicine in California treatment of patients under its auspices. until 1941, when he entered the US His widow. Mrs. Alice Williams. and Army. He was discharged with the rank other family members have established of major in 1945, and the Trelstads the Dr. George E. Williams Memorial moved to Oregon in 1946. He is sur­ Scholarship Fund. Contributions may vived by his wife, Adelaide, three sons, be sent to the Fund through the Minne­ two of whom are doctors, and two step­ sota Medical Foundation, Box 193, daughters. Health Sciences Center, University of Minnesota, Minneapolis, MN 55455. 36

Announcing-

Two new estate planning brochures from Minnesota Medical Foundation:

"Your Will- New Tax Law Strategies"

Tells how to take full advantage of the changes / brought about by ERTA- the Economic Recovery Tax Act of 1981. Whether or not you already have a will, this booklet provides important, up-to-date information for you.

"Planning for Your Successful Retirement"

Retirement planning involves a variety of personal and financial decisions. This pamphlet will help you examine the questions that must be raised as you reflect upon retirement and your own planning needs. ·------

Mail to: Minnesota Medical Foundation 0 Please send "Your Will­ 535 Diehl Hall New Tax Law Strategies" University of Minnesota Minneapolis, MN 55455 0 Please send "Planning For Your Successful Retirement"

Or use the business reply envelope bound into the middle of this Bulletin.

Name ______

Address ______------

City------State ______Zip--- We Need Your Help'

For the 1982 edition of the University of Minnesota Medical Alumni Direc­ tory we need to update and correct our records. You can help us to find your classmates and friends. Some may have died: others have moved: others have changed their names. If you know the current address of any of the following alumni, please get in touch with Kay Geoffrey. room 535. Diehl Hall, University of Minnesota. Minneapolis. MN 55455: (612) 373-8023. Thank you'

For these alumni. the last address we have is not correct:

1940 1948 1963 Carl A. Hanson Alexander M. Boysen David B. Youel 330 South St. 523 G Murphy Circle 159 D E. Pike St. Waterloo. IA Ft. McPherson. GA Pontiac. MI 1964 1943 Joyce S. Lewis. Jr. James D. Lehmann Erling G. Hestenes San Diego, CA Parkland Memorial Hospital Mission Hospital - Zululand Dallas. TX Hlabisa. Rep. of South Africa 1959 Wilfred A. Corson R H. Richardson Clinton F. Snyder Firland Sanatorium 229 Arthur SE Edgewood Arsenal, MD Seattle. WA Minneapolis. MN 55414 Lawrence G. Thouin 1962 1965 1620 West Ave. S. Jay T. Ballhagen Gerald C. Peterson Lancaster. CA 3100 S. Sheridan Blvd. Peace Corps Denver. CO Caracas. Venezuela 1944 Wallace A. Rogers Joseph P. Belshe Charles S. Ostrov Parasitology Unit 5025 Garfield S. Cincinnati General Hospital Center for Disease Control Mpls .. MN Cincinnati. OH Atlanta. GA Calvin L. Strand Hennepin County Medical Center Mpls. MN For these alumni. we have no addresses:

1909 1936 1944 J J. Buckley C. J. Bell P. Lawson W. POlson D. Peterson A. L. Vadheim L Van Deboget 1937 C. M. Biddle 1945 1910 R A. Globe P. Jewsbury J. J Petit H. Katzovitz J. McFie E. M. Watson A. E. Miller W. W. Wood 1946 1931 B. Levin Paul L. Eneboe 1938 J. Locken M. Shaw R A. Collins H. Peir Stevenson C. G. Wingquist

1932 1939 1947 L L Freidman William Birnbaum C. Paterson A. M. Nielson 1933 1949 R C. Paulson 1940 A. H. Tallakson C. S Tierney Betty J Hall Taylor W. Woltjen 1934 R B. Boetiner 1943 1953 S Mullin I. L. Gilinsky RD. Pugsley J Neander 1935 0. Rotnem Herbert A. Blumenthal P. Russell 1957 D. N. Rudin A. Welte W. J. Anderson