PRODUCT DATA SHEET Bioworld Technology,Inc.

BHLHB2 polyclonal antibody

Catalog: BS6451 Host: Rabbit Reactivity: Human,Mouse,Rat

BackGround: Specificity: Human DEC1, also known as SHARP2, is a 412 amino BHLHB2 polyclonal antibody detects endogenous levels acid, basic helix-loop-helix (bHLH) containing of BHLHB2 protein. that is involved in the control of proliferation and/or dif- DATA: ferentiation of several cell types including nerve cells, fi- broblasts and chondrocytes. The bHLH region of DEC1 is structurally similar to the bHLH regions of the mamma- lian HES family, Drosophila hairy and Drosophila En- hancer of split m7. DEC1 is a novel direct target for cAMP in a wide range of cells, and is involved in the control of expression in cAMP-activated cells. Brief light impulses induce the expression of DEC1 in a Western blot analysis of extracts of various cell lines, using BHLHE40 phase-dependent manner. DEC1 is highly expressed in antibody. cartilage, intestine, lung and spleen. DEC1 and DEC2 play a role in regulating the mammalian molecular by suppressing the transcription of specific clock . Both DEC1 and DEC2 are detected in the suprachiasmic nucleus in a circadian fashion. Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2 Immunohistochemistry of paraffin-embedded Mouse lung using BHL- Molecular Weight: HE40 antibody at dilution of 1:100 (x400 lens). ~ 46 kDa Swiss-Prot: O14503 Purification&Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific im- munogen and the purity is > 95% (by SDS-PAGE). Immunofluorescence analysis of HeLa cell using BHLHE40 antibody. Applications: Blue: DAPI for nuclear staining. WB 1:500 - 1:2000 Note: IHC 1:50 - 1:200 For research use only, not for use in diagnostic procedure. IF 1:50 - 1:200 Storage&Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Technology, Inc. Bioworld technology, co. Ltd. Add: 1660 South Highway 100, Suite 500 St. Louis Park, Add: No 9, weidi road Qixia District Nanjing, 210046, MN 55416,USA. P. R. China. Email: [email protected] Email: [email protected] Tel: 6123263284 Tel: 0086-025-68037686 Fax: 6122933841 Fax: 0086-025-68035151

PRODUCT DATA SHEET Bioworld Technology,Inc.

Bioworld Technology, Inc. Bioworld technology, co. Ltd. Add: 1660 South Highway 100, Suite 500 St. Louis Park, Add: No 9, weidi road Qixia District Nanjing, 210046, MN 55416,USA. P. R. China. Email: [email protected] Email: [email protected] Tel: 6123263284 Tel: 0086-025-68037686 Fax: 6122933841 Fax: 0086-025-68035151