GEMIN8 Antibody Cat. No.: 59-561

GEMIN8 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human

HOMOLOGY: Predicted species reactivity based on immunogen sequence: Bovine, Mouse

This GEMIN8 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 213-239 amino acids from the C-terminal region of human GEMIN8.

TESTED APPLICATIONS: WB

APPLICATIONS: For WB starting dilution is: 1:1000

PREDICTED MOLECULAR 29 kDa WEIGHT:

Properties

This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification.

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

September 26, 2021 1 https://www.prosci-inc.com/gemin8-antibody-59-561.html CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: GEMIN8

ALTERNATE NAMES: Gem-associated protein 8, Gemin-8, Protein FAM51A1, GEMIN8, FAM51A1

ACCESSION NO.: Q9NWZ8

PROTEIN GI NO.: 52782795

GENE ID: 54960

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating BACKGROUND: their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

REFERENCES: 1) Carissimi, C., et al. J. Biol. Chem. 281(48):37009-37016(2006)

2) Carissimi, C., et al. J. Biol. Chem. 281(12):8126-8134(2006)

ANTIBODIES FOR RESEARCH USE ONLY.

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September 26, 2021 2 https://www.prosci-inc.com/gemin8-antibody-59-561.html