Commonly Used Substance Use Disorder Screening Instruments
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Smoking Cessation Treatment at Substance Abuse Rehabilitation Programs
SMOKING CEssATION TREATMENT AT SUBSTANCE ABUSE REHABILITATION PROGRAMS Malcolm S. Reid, PhD, New York University School of Medicine, Department of Psychiatry; Jeff Sel- zer, MD, North Shore Long Island Jewish Healthcare System; John Rotrosen, MD, New York University School of Medicine, Department of Psychiatry Cigarette smoking is common among persons with drug and alcohol n Nicotine is a highly use disorders, with prevalence rates of 80-90% among patients in sub- addictive substance stance use disorder treatment programs. Such concurrent smoking may that meets all of produce adverse behavioral and medical problems, and is associated the criteria for drug with greater levels of substance use disorder. dependence. CBehavioral studies indicate that the act of cigarette smoking serves as a cue for drug and alcohol craving, and the active ingredient of cigarettes, nicotine, serves as a primer for drug and alcohol abuse (Sees and Clarke, 1993; Reid et al., 1998). More critically, longitudinal studies have found tobacco use to be the number one cause of preventable death in the United States, and also the single highest contributor to mortality in patients treated for alcoholism (Hurt et al., 1996). Nicotine is a highly addictive substance that meets all of the criteria for drug dependence, and cigarette smoking is an especially effective method for the delivery of nicotine, producing peak brain levels within 15-20 seconds. This rapid drug delivery is one of a number of common properties that cigarette smok- ing shares with hazardous drug and alcohol use, such as the ability to activate the dopamine system in the reward circuitry of the brain. -
Alcohol, Tobacco, and Prescription Drugs: the Relationship with Illicit Drugs in the Treatment of Substance Users
Macquarie University ResearchOnline This is the author version of an article published as: Teesson, M., Farrugia, P., Mills, K., Hall, W., & Baillie, A. (2012). Alcohol, tobacco, and prescription drugs: The relationship with illicit drugs in the treatment of substance users. Substance use & misuse, Vol. 47, Issue 8-9, p. 963-971. Access to the published version: http://doi.org/10.3109/10826084.2012.663283 Copyright: Copyright the Publisher 2012. Version archived for private and non- commercial use with the permission of the author/s and according to publisher conditions. For further rights please contact the publisher. Comorbidity 1 Alcohol, tobacco and prescription drugs: The relationship with illicit drugs in the treatment of substance users. Maree Teesson, Philippa Farrugia, Katherine Mills 1 Wayne Hall2, Andrew Baillie3. 1. National Drug and Alcohol Research Centre, University of New South Wales, Sydney, New South Wales 2052 Australia, 2. University of Queensland Centre for Clinical Research, 3. Centre for Emotional Health, Department of Psychology, Macquarie University. * Corresponding author: Maree Teesson National Drug and Alcohol Research Centre University of New South Wales, Sydney New South Wales 2052 Australia Tel: +61 2 9385 0333; fax: +61 2 9385 0222; email: [email protected] Abstract Alcohol, tobacco, prescription drug and illicit drug use frequently co-occur. This paper reviews the extent of this co-occurrence in both general population samples and clinical samples, and its impact on treatment outcome. We argue that the research base for understanding comorbidity between tobacco, alcohol, prescription and illicit drugs needs to be broadened. We specifically advocate for: 1) more epidemiological studies of relationships between alcohol, tobacco and other illicit drug use; and 2) increased research on treatment options that address the problematic use of all of these drugs. -
Concurrent Alcohol and Tobacco Dependence
Concurrent Alcohol and Tobacco Dependence Mechanisms and Treatment David J. Drobes, Ph.D. People who drink alcohol often also smoke and vice versa. Several mechanisms may contribute to concurrent alcohol and tobacco use. These mechanisms include genes that are involved in regulating certain brain chemical systems; neurobiological mechanisms, such as cross-tolerance and cross-sensitization to both drugs; conditioning mechanisms, in which cravings for alcohol or nicotine are elicited by certain environmental cues; and psychosocial factors (e.g., personality characteristics and coexisting psychiatric disorders). Treatment outcomes for patients addicted to both alcohol and nicotine are generally worse than for people addicted to only one drug, and many treatment providers do not promote smoking cessation during alcoholism treatment. Recent findings suggest, however, that concurrent treatment for both addictions may improve treatment outcomes. KEY WORDS: comorbidity; AODD (alcohol and other drug dependence); alcoholic beverage; tobacco in any form; nicotine; smoking; genetic linkage; cross-tolerance; AOD (alcohol and other drug) sensitivity; neurotransmitters; brain reward pathway; cue reactivity; social AODU (AOD use); cessation of AODU; treatment outcome; combined modality therapy; literature review lcohol consumption and tobacco ers who are dependent on nicotine Department of Health and Human use are closely linked behaviors. have a 2.7 times greater risk of becoming Services 1989). The concurrent use of A Thus, not only are people who alcohol dependent than nonsmokers both drugs by pregnant women can drink alcohol more likely to smoke (and (e.g., Breslau 1995). Finally, although also result in more severe prenatal dam- vice versa) but also people who drink the smoking rate in the general popula age and neurocognitive deficits in their larger amounts of alcohol tend to smoke tion has gradually declined over the offspring than use of either drug alone more cigarettes. -
Substance Abuse: the Pharmacy Educator’S Role in Prevention and Recovery
Substance Abuse: The Pharmacy Educator’s Role in Prevention and Recovery Curricular Guidelines for Pharmacy: Substance Abuse and Addictive Disease i Curricular Guidelines for Pharmacy: Substance Abuse and Addictive Disease1,2 BACKGROUND OF THE CURRICULUM DEVELOPMENT PROJECT In 1988, the AACP Special Interest Group (SIG) on Pharmacy Student and Faculty Impairment (renamed Substance Abuse Education and Assistance) undertook the development of curricular guidelines for colleges/schools of pharmacy to facilitate the growth of educational opportunities for student pharmacists. These Curricular Guidelines for Pharmacy Education: Substance Abuse and Addictive Disease were published in 1991 (AJPE. 55:311-16. Winter 1991.) One of the charges of the Special Committee on Substance Abuse and Pharmacy Education was to review and revise the 1991 curricular guidelines. Overall, the didactic and experiential components in the suggested curriculum should prepare the student pharmacist to competently problem-solve issues concerning alcohol and other drug abuse and addictive diseases affecting patients, families, colleagues, themselves, and society. The guidelines provide ten educational goals, while describing four major content areas including: psychosocial aspects of alcohol and other drug use; pharmacology and toxicology of abused substances; identification, intervention, and treatment of people with addictive diseases; and legal/ethical issues. The required curriculum suggested by these guidelines addresses the 1 These guidelines were revised by the AACP Special Committee on Substance Abuse and Pharmacy Education. Members drafting the revised guidelines were Edward M. DeSimone (Creighton University), Julie C. Kissack (Harding University), David M. Scott (North Dakota State University), and Brandon J. Patterson (University of Iowa). Other Committee members were Paul W. Jungnickel, Chair (Auburn University), Lisa A. -
Barriers and Solutions to Addressing Tobacco Dependence in Addiction Treatment Programs
Barriers and Solutions to Addressing Tobacco Dependence in Addiction Treatment Programs Douglas M. Ziedonis, M.D., M.P.H.; Joseph Guydish, Ph.D., M.P.H.; Jill Williams, M.D.; Marc Steinberg, Ph.D.; and Jonathan Foulds, Ph.D. Despite the high prevalence of tobacco use among people with substance use disorders, tobacco dependence is often overlooked in addiction treatment programs. Several studies and a meta-analytic review have concluded that patients who receive tobacco dependence treatment during addiction treatment have better overall substance abuse treatment outcomes compared with those who do not. Barriers that contribute to the lack of attention given to this important problem include staff attitudes about and use of tobacco, lack of adequate staff training to address tobacco use, unfounded fears among treatment staff and administration regarding tobacco policies, and limited tobacco dependence treatment resources. Specific clinical-, program-, and system-level changes are recommended to fully address the problem of tobacco use among alcohol and other drug abuse patients. KEY WORDS: Alcohol and tobacco; alcohol, tobacco, and other drug (ATOD) use, abuse, dependence; addiction care; tobacco dependence; smoking; secondhand smoke; nicotine; nicotine replacement; tobacco dependence screening; tobacco dependence treatment; treatment facility-based prevention; co-treatment; treatment issues; treatment barriers; treatment provider characteristics; treatment staff; staff training; AODD counselor; client counselor interaction; smoking cessation; Tobacco Dependence Program at the University of Medicine and Dentistry of New Jersey obacco dependence is one of to the other. The common genetic vul stance use was considered a potential the most common substance use nerability may be located on chromo trigger for the primary addiction. -
Vol. 1, Issue 1
Methamphetamine Topical Brief Series: Vol. 1, Issue 1 What is countries involved in World War II provided amphetamine to soldiers Methamphetamine? for performance enhancement and the drug was used by “actors, artists, Methamphetamine is an addictive, athletes, politicians, and the public stimulant drug that affects the alike.”5 central nervous system. It is typically used in powder or pill form and can By the 1960s, media coverage be ingested orally, snorted, smoked, began drawing simplistic, negative or injected. Methamphetamine is connections between amphetamine known as meth, blue, ice, speed, and and crime, and government officials 1 crystal among other names. The term discussed public safety and drugs amphetamine has been used broadly as a social concern.6 Over-the- to refer to a group of chemicals that counter amphetamines were have similar, stimulating properties available until 1959,7 and by 1970 and methamphetamine is included in all amphetamines were added to 2 this group. According to the National the controlled substances list as Institute on Drug Abuse (NIDA), Schedule II drugs. Schedule II drugs “Methamphetamine differs from required a new prescription with amphetamine in that, at comparable each fill and strict documentation doses, much greater amounts of the by doctors and pharmacists.8 drug get into the brain, making it a The reduction in a legal supply 3 more potent stimulant.” of amphetamine led to increased black-market production and sale From the 1930s to the 1960s, of various types of amphetamine U.S. pharmaceutical -
Drug Use and Gender
Drug Use and Gender Tammy L. Anderson, Ph.D. University of lllinois, Chicago, lL GENDER DIFFERENCES IN study-report a greater occurrence ofillicit substance use DRUG USE AND ABUSE among males than among females. Both surveys have consistently documented this pattern over the years. Looking at the world through a "gender lens" began According to the 1997 NHSDA survey, men reported a in most areas of social science during the second wave of higher rate of illicit substance use (any illicit drug) than the women's movement, or the late 1960s through the women, 8.5 percent to 4.5 percent, nearly double. Men 1970s. During this time feminist researchers began report higher rates of cocaine use .9 percent versus .5 questioning science's conclusions by pointing to percent. alcohol use (58 percent versus 45 percent), binge male-oriented biases in research questions, hypotheses, drinking (23 percent versus 8 percent), and heavy drinking and designs. (8.7 percent versus 2.1 percent). The same pattern was Unfortunately, the "gender lens" did not appear in observed in marijuana use (Office of Applied Studies substance use research until the early 1980s. Prior to the [OAS] tee7). 1970s, most studies of alcohol and other drug use were Johnston. O'Malley, and Bachman (1997) the conducted among males. Early studies that included at University of Michigan yearly women suffered from the "add women and stir compile data on the substance use of 8th. 10th, and 12th graders, college students, approach." Females were added to samples, but no and young adults in the MTF study. -
Evidence-Based Guidelines for the Pharmacological Management of Substance Abuse, Harmful Use, Addictio
444324 JOP0010.1177/0269881112444324Lingford-Hughes et al.Journal of Psychopharmacology 2012 BAP Guidelines BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, Journal of Psychopharmacology 0(0) 1 –54 harmful use, addiction and comorbidity: © The Author(s) 2012 Reprints and permission: sagepub.co.uk/journalsPermissions.nav recommendations from BAP DOI: 10.1177/0269881112444324 jop.sagepub.com AR Lingford-Hughes1, S Welch2, L Peters3 and DJ Nutt 1 With expert reviewers (in alphabetical order): Ball D, Buntwal N, Chick J, Crome I, Daly C, Dar K, Day E, Duka T, Finch E, Law F, Marshall EJ, Munafo M, Myles J, Porter S, Raistrick D, Reed LJ, Reid A, Sell L, Sinclair J, Tyrer P, West R, Williams T, Winstock A Abstract The British Association for Psychopharmacology guidelines for the treatment of substance abuse, harmful use, addiction and comorbidity with psychiatric disorders primarily focus on their pharmacological management. They are based explicitly on the available evidence and presented as recommendations to aid clinical decision making for practitioners alongside a detailed review of the evidence. A consensus meeting, involving experts in the treatment of these disorders, reviewed key areas and considered the strength of the evidence and clinical implications. The guidelines were drawn up after feedback from participants. The guidelines primarily cover the pharmacological management of withdrawal, short- and long-term substitution, maintenance of abstinence and prevention of complications, where appropriate, for substance abuse or harmful use or addiction as well management in pregnancy, comorbidity with psychiatric disorders and in younger and older people. Keywords Substance misuse, addiction, guidelines, pharmacotherapy, comorbidity Introduction guidelines (e.g. -
Opioid and Nicotine Use, Dependence, and Recovery: Influences of Sex and Gender
Opioid and Nicotine: Influences of Sex and Gender Conference Report: Opioid and Nicotine Use, Dependence, and Recovery: Influences of Sex and Gender Authors: Bridget M. Nugent, PhD. Staff Fellow, FDA OWH Emily Ayuso, MS. ORISE Fellow, FDA OWH Rebekah Zinn, PhD. Health Program Coordinator, FDA OWH Erin South, PharmD. Pharmacist, FDA OWH Cora Lee Wetherington, PhD. Women & Sex/Gender Differences Research Coordinator, NIH NIDA Sherry McKee, PhD. Professor, Psychiatry; Director, Yale Behavioral Pharmacology Laboratory Jill Becker, PhD. Biopsychology Area Chair, Patricia Y. Gurin Collegiate Professor of Psychology and Research Professor, Molecular and Behavioral Neuroscience Institute, University of Michigan Hendrée E. Jones, Professor, Department of Obstetrics and Gynecology; Executive Director, Horizons, University of North Carolina at Chapel Hill Marjorie Jenkins, MD, MEdHP, FACP. Director, Medical Initiatives and Scientific Engagement, FDA OWH Acknowledgements: We would like to acknowledge and extend our gratitude to the meeting’s speakers and panel moderators: Mitra Ahadpour, Kelly Barth, Jill Becker, Kathleen Brady, Tony Campbell, Marilyn Carroll, Janine Clayton, Wilson Compton, Terri Cornelison, Teresa Franklin, Maciej Goniewcz, Shelly Greenfield, Gioia Guerrieri, Scott Gottlieb, Marsha Henderson, RADM Denise Hinton, Marjorie Jenkins, Hendrée Jones, Brian King, George Koob, Christine Lee, Sherry McKee, Tamra Meyer, Jeffery Mogil, Ann Murphy, Christine Nguyen, Cheryl Oncken, Kenneth Perkins, Yvonne Prutzman, Mehmet Sofuoglu, Jack Stein, Michelle Tarver, Martin Teicher, Mishka Terplan, RADM Sylvia Trent-Adams, Rita Valentino, Brenna VanFrank, Nora Volkow, Cora Lee Wetherington, Scott Winiecki, Mitch Zeller. We would also like to thank those who helped us plan this program. Our Executive Steering Committee included Ami Bahde, Carolyn Dresler, Celia Winchell, Cora Lee Wetherington, Jessica Tytel, Marjorie Jenkins, Pamela Scott, Rita Valentino, Tamra Meyer, and Terri Cornelison. -
A Molecular Basis for Nicotine As a Gateway Drug
The new england journal of medicine special article shattuck lecture A Molecular Basis for Nicotine as a Gateway Drug Eric R. Kandel, M.D., and Denise B. Kandel, Ph.D. From the Howard Hughes Medical Insti- n the historic occasion of the 122nd Shattuck Lecture and tute (E.R.K.), Kavli Institute for Brain Sci- the 200th anniversary of the New England Journal of Medicine, we chose to ad- ence (E.R.K.), and the Departments of Neuroscience (E.R.K.) and Psychiatry Odress a topic that is at once scientific and personally historic. In recent (E.R.K., D.B.K.), College of Physicians debates over legalizing marijuana, from all-out acceptance in Colorado to narrow and Surgeons, and Mailman School of decriminalization in Maryland, the scientific question of the role of marijuana as a Public Health (D.B.K.), Columbia Univer- sity, and the New York State Psychiatric gateway drug (i.e., a drug that lowers the threshold for addiction to other agents) Institute (D.B.K.) — all in New York. Ad- has loomed large. Both opponents and proponents of legalization have distorted dress reprint requests to Dr. E. Kandel at what science does and does not tell us — and both sides have overlooked the im- the Department of Neuroscience, Col- lege of Physicians and Surgeons, Colum- portance of nicotine as a gateway drug. bia University, 1051 Riverside Dr., Unit Epidemiologic studies have shown that nicotine use is a gateway to the use of 87, New York, NY 10032, or at erk5@ marijuana and cocaine in human populations. -
Adults with Attention Deficit Hyperactivity Disorder and Substance Use Disorders
ADVISORY Behavioral Health Is Essential To Health • Prevention Works • Treatment Is Effective • People Recover Adults With Attention Deficit Hyperactivity Disorder and Substance Use Disorders Attention deficit hyperactivity disorder (ADHD) Which ADHD symptoms are most prominent is one of the most common childhood mental varies with age and circumstance. The hyper- disorders, and it can persist through adolescence activity symptoms are usually the most noticeable and adulthood. The medications most commonly during the preschool and elementary school used to treat ADHD are stimulants, and survey years. Late in elementary and middle school, the inattention symptoms come to the fore.2 data show that abuse of prescription stimulants Among adolescents, hyperactivity may be limited is on the rise. This Advisory discusses the co- to fidgeting and be experienced as feelings of occurrence of ADHD and substance use disorders jitteriness and impatience. DSM-5 notes that (SUDs), the misuse of prescription stimulants, ADHD symptoms wax and wane depending and treatment and prevention approaches to on the circumstance. Close supervision, a new these problems. setting, an engrossing activity, or frequent rewards for appropriate behavior may make symptoms go The Definition of ADHD away temporarily.1 According to the Diagnostic and Statistical Adult ADHD Manual of Mental Disorders (5th ed.; DSM-5),1 the essential feature of ADHD is a persistent For many years, experts believed that children 3 pattern of inattention, hyperactivity-impulsivity and adolescents outgrew ADHD. However, (they are grouped together), or both that interferes research that followed children with ADHD into adulthood showed that the condition can persist with normal functioning and development.1 into adulthood. -
ADHD and Co-Morbid Substance Use Disorder – a Guide for Clinicians
ADHD and co-morbid substance use disorder – a guide for clinicians Background ADHD is a heterogenous behavioural syndrome characterised by the core symptoms of hyperactivity, impulsivity and inattention. While these symptoms tend to cluster together, some people are predominantly hyperactive and impulsive while others are inattentive. Most young people do not use illicit drugs and among those who do only a small number will develop serious problems.1 ADHD and substance misuse can often co-occur.1 However, most studies of ADHD treatment typically exclude those with a substance use disorder.2 Pharmacological treatment of ADHD should not be postponed pending resolution of substance misuse.1 Individuals with substance use disorders (SUDs) and ADHD have an earlier onset of substance abuse than those without ADHD, a greater likelihood of having continuous problems if they develop substance dependence, a reduced likelihood of going into remission, and a tendency to take longer to reach remission. The diagnosis and treatment of ADHD in patients with SUD is essential to achieve the best possible outcome.3 Although the British Association for Psychopharmacology (BAP) highlight that it is unclear what the ideal management of people with concurrent substance use disorders is (e.g. detoxification/behavioural modification before, after or combined with ADHD treatment),4 others suggest that the simultaneous treatment of both conditions is likely to be the optimal approach because ADHD symptoms will interfere with SUD treatment, and substance use will limit the benefit of ADHD treatment.3 In addition, existing evidence indicates that treatment of ADHD with medication does not exacerbate SUD2 or increase the risk of the development of substance misuse in the treated individual.1,5 These guidelines should be read alongside other current guidance (NICE, Trust guidelines and Shared Care Protocols) and they are intended to support a treatment strategy for young people and adults with ADHD who have a co-morbid SUD.