Recombinant Cynomolgus Cd3d/CD3 Delta Protein

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Recombinant Cynomolgus CD3d/CD3 delta Protein

Catalog No.: RP00778 Recombinant

Sequence Information Background

Species Gene ID Swiss Prot T-cell surface glycoprotein CD3 delta chain (CD3D) is a single-pass type I Cynomolgus 102133701 Q95LI8 membrane protein. CD3D, togetherwith CD3-gamma, CD3-epsilon and CD3-zeta, and the T-cell receptor alpha/beta and gamma/deltaheterodimers, forms the T Tags cell receptor-CD3 complex. CD3 chains are present as 6×His tag at the C-terminus CD3gammaepsilon,deltaepsilon, and zetazeta dimers in the receptor complex and play critical roles in the antigen receptorassembly, transport to the cell surface, Synonyms and the receptor-mediated signal transduction. T cell receptor-CD3complex plays T-cell surface glycoprotein CD3 delta an important role in coupling antigen recognition to several intracellular signal- chain; T-cell receptor T3 delta chain; transductionpathways. This complex is critical for T-cell development and CD3d; CD3D function, and represents one of the mostcomplex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmicimmunoreceptor tyrosine-based activation motifs(ITAMs). CD3D contains 1 ITAM domain and has Product Information been shownto interact with CD8A.

Source Purification Basic Information Human Cells > 95% by SDS- PAGE. Description Endotoxin Recombinant Cynomolgus CD3d/CD3 delta Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Phe22-Ala105) < 1 EU/μg of the protein by LAL of cynomolgus CD3d/CD3 delta Protein (Accession #Q95LI8) fused with a 6×His tag method. at the C-terminus. Formulation Bio-Activity Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4. Contact us for customized product Storage form or formulation. Store the lyophilized protein at -20°C to -80 °C for long term. After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C Reconstitution for up to 1 week. Avoid repeated freeze/thaw cycles. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water.

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Recombinant Cynomolgus CD3d/CD3 delta Protein was determined by SDS-PAGE under reducing conditions with Coomassie Blue.