CDH4 Antibody Cat. No.: 26-035

CDH4 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse, Rat

Antibody produced in rabbits immunized with a synthetic peptide corresponding a region IMMUNOGEN: of human CDH4.

TESTED APPLICATIONS: ELISA, WB

CDH4 antibody can be used for detection of CDH4 by ELISA at 1:62500. CDH4 antibody APPLICATIONS: can be used for detection of CDH4 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

POSITIVE CONTROL: 1) Cat. No. 1211 - HepG2 Cell Lysate

PREDICTED MOLECULAR 82 kDa WEIGHT:

Properties

PURIFICATION: Antibody is purified by peptide affinity chromatography method.

CLONALITY: Polyclonal

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

September 25, 2021 1 https://www.prosci-inc.com/cdh4-antibody-26-035.html Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% BUFFER: sucrose.

CONCENTRATION: batch dependent

For short periods of storage (days) store at 4˚C. For longer periods of storage, store CDH4 STORAGE CONDITIONS: antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Additional Info

OFFICIAL SYMBOL: CDH4

ALTERNATE NAMES: CDH4, CAD4, FLJ22202, FLJ40547, MGC126700, MGC138355, RCAD

ACCESSION NO.: NP_001785

PROTEIN GI NO.: 14589893

GENE ID: 1002

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

CDH4 is a classical from the cadherin superfamily. The is a calcium- dependent cell- glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis- heterodimers of 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.This gene is a classical cadherin from the cadherin superfamily. The BACKGROUND: encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.

REFERENCES: 1) Maeda, M., (2006) Oncogene 25 (33), 4595-4604.

ANTIBODIES FOR RESEARCH USE ONLY.

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