Program & Abstract Book 2019
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2nd OFFICIAL SIPS CONFERENCE ON PLACEBO STUDIES Program & Abstract book July 7 - 9, 2019 Leiden, the Netherlands Welcome Dear attendee of the 2019 SIPS conference, It is our great pleasure to welcome you to the 2nd official Society for Interdisciplinary Placebo Studies (SIPS) conference on placebo studies. The conference venue is the beautiful historic Stadsgehoorzaal in Leiden, the Netherlands. This second edition of the SIPS conference promises to be very inspiring. We highly appreciate that so many researchers contributed to the rich and varied conference program and made their way to attend the conference. The SIPS conference is devoted to the interdisciplinary study of placebo effects. It focuses on medical, psychosocial, philosophical, and neurobiological research on placebo and nocebo effects, and also addresses ethical dilemmas and treatment options. The range of topics mirrors the efforts of SIPS to advance research on knowledge of placebo and nocebo effects and to eventually improve clinical care. Next to the keynote speakers and the invited speakers, we are pleased to offer a diverse scientific program due to the many submitted contributions, with different parallel sessions to choose from. We are also very pleased to invite you to the conference dinner which will take place on Monday evening July 8, at beachclub BAIT in Wassenaar. The busses for the dinner will leave at 7 PM from the Stadsgehoorzaal in Leiden and will return to the conference location at 11 PM. We hope that this conference will foster the exchange of new ideas and promote new contacts between researchers on the placebo effect. We wish you an inspirational and fruitful conference, and hope that you will enjoy everything the conference and the beautiful city of Leiden has to offer! Sincerely, On behalf of the SIPS conference and steering committees, Andrea W.M. Evers Chair SIPS conference 2019 SIPS Conference Committee SIPS Steering Committee Andrea Evers (chair) John Kelley (chair) Judy Veldhuijzen Jens Gaab Kaya Peerdeman Charlotte Blease Liesbeth van Vliet Luana Colloca Aleksandrina Skvortsova Karin Jensen Stefanie Meeuwis Lene Vase Jaap-Willem Mink Irving Kirsch Atie Breugem Bruce Wampold The SIPS conference is sponsored by: - 1 - The SIPS Conference Committee Andrea Evers Judy Veldhuijzen Kaya Peerdeman Liesbeth van Vliet Aleksandrina Stefanie Meeuwis Jaap-Willem Mink Atie Breugem Skvortsova The SIPS Steering Committee John Kelley Jens Gaab Charlotte Blease Luana Colloca Karin Jensen Lene Vase Irving Kirsch Bruce Wampold - 2 - Contents Program Conference Day 1: Sunday July 7, 2019 ................................................................................................. 5 Conference Day 2: Monday July 8, 2019 ................................................................................................ 6 Conference Day 3: Tuesday July 9, 2019 ............................................................................................... 7 Sunday July 7 ........................................................................................................................................ 9 Keynote lecture: Jet Bussemaker .......................................................................................................... 10 Keynote lecture: Luana Colloca ............................................................................................................ 11 Selected Poster Session 1 .................................................................................................................... 12 Monday July 8 ...................................................................................................................................... 17 Keynote lecture: Tor Wager ................................................................................................................... 18 Plenary Session 1 How to use placebos in clinical practice? .............................................................. 19 Parallel Session 1.1 The power of nocebo: From mechanisms to clinical application ........................ 22 Parallel Session 1.2 Psychopharmacology and psychophysiology in placebo studies ...................... 24 Parallel Session 1.3 Placebo response and treatment expectations in clinical populations ............... 26 Parallel Session 1.4 What's in a definition: Conceptualizing placebo ................................................. 28 Parallel Session 1.5 Context matters! Contextual factors in placebo effects ...................................... 30 Poster Session 2 ................................................................................................................................... 32 Plenary Session 2 Neurobiological and pharmacological underpinnings of placebo effects .............. 51 Plenary Session 3 Nocebo: Expecting harmful effects will make you ill ............................................. 54 Keynote lecture: Ionica Smeets ............................................................................................................. 57 Tuesday July 9 ..................................................................................................................................... 59 Keynote lecture: Irving Kirsch ................................................................................................................ 60 Plenary Session 4 The future of placebo: Conceptualizations and beyond ........................................ 61 Parallel Session 2.1 Open up about placebos: Open label placebo applications ............................... 64 Parallel Session 2.2 From genes to expectancies: Predicting placebo effects ................................... 66 Parallel Session 2.3 New applications of traditional conditioning paradigms ..................................... 68 Parallel Session 2.4 Placebo effects in psychotherapy and neurocognitive disorders ....................... 70 Parallel Session 2.5 Placebo and nocebo effects on cognition ........................................................... 72 Poster Session 3 ................................................................................................................................... 74 Parallel Session 3.1 Neural mechanisms in placebo studies .............................................................. 94 Parallel Session 3.2 Placebo effects in clinician-patient interactions .................................................. 96 Parallel Session 3.3 Placebo effects in children and adolescents ...................................................... 98 Parallel Session 3.4 Innovative ways to enhance placebo analgesia ............................................... 100 Parallel Session 3.5 Novel perspectives on placebo effects ............................................................. 102 Plenary Session 5 Novel neuroimaging findings: How do placebo effects work? ............................. 104 Practicalities......................................................................................................................................... 107 Accreditation ........................................................................................................................................ 112 Notes ................................................................................................................................................... 113 - 3 - - 4 - Conference Day 1: Sunday July 7, 2019 Conference venue: Stadsgehoorzaal, Leiden Time Activity Location 03:00 PM Registration Entree Foyer 04:00 PM Conference Opening Grote Zaal John Kelley (President SIPS) Special Welcome Henri Lenferink (Mayor Leiden) Short welcome Andrea Evers (Chair conference committee) Keynote Lecture Jet Bussemaker - Breaking the boundaries Keynote Lecture Luana Colloca - Mechanisms of observationally-induced pain modulation: From placebo effects to virtual reality Travel awards ceremony 06.00 - Opening reception and selected poster presentations Catharina Foyer 07.30 PM - 5 - Conference Day 2: Monday July 8, 2019 Conference venue: Stadsgehoorzaal, Leiden Time Activity Location 08:00 AM Registration and welcome with coffee and tea Entree Foyer 08:30 AM Keynote Lecture Grote Zaal Tor Wager - Placebos, therapy, and self-fulfilling prophecies 09:15 AM Plenary session 1 Grote Zaal How to use placebos in clinical practice? 11:00 AM Coffee break Catharina Foyer 11:30 AM Parallel sessions 1 1.1 The power of nocebo: From mechanisms to clinical Grote Zaal application 1.2 Psychopharmacology and psychophysiology in Aalmarktzaal placebo studies 1.3 Placebo response and treatment expectations in Breezaal clinical populations 1.4 What’s in a definition: Conceptualizing placebo Jan Willem Schaap zaal 1.5 Context matters! Contextual factors in placebo effects Cornelis Schuytzaal 12:30 PM Lunch Catharina Foyer 1:00 PM Poster presentations / Lunch Catharina Foyer 02:00 PM Plenary session 2 Grote Zaal Neurobiological and pharmacological underpinnings of placebo effects 03:45 PM Coffee break Catharina Foyer 04:15 PM Plenary session 3 Grote Zaal Nocebo: Expecting harmful effects will make you ill 06:00 PM Keynote Lecture Grote Zaal Ionica Smeets - This study will change your life – health news in the media 06:45 PM Short break 07:00 PM Busses depart from conference location 07:30 PM Conference dinner Beachclub BAIT Wassenaar 11:00 PM Busses return to conference location - 6 - Conference Day 3: Tuesday July 9, 2019 Conference venue: Stadsgehoorzaal, Leiden Time Activity Location 08:00 AM Registration and welcome with coffee and tea Entree