Curriculum Vita

Name Hitoshi Morikawa, MD/PhD

Business Address University of Texas at Austin Department of and Waggoner Center for Alcohol and Research 2400 Speedway, PAT 402 Austin, TX 78712 Phone: (512) 232-9299 Fax: (512) 471-3878 E-mail: [email protected]

Education 1990 MD, Kyoto University Faculty of Medicine, Kyoto, Japan 1994 – 1997 Medical Science Graduate Program, Kyoto University Faculty of Medicine, Kyoto, Japan 1999 PhD in Medical Science, Kyoto University Faculty of Medicine, Kyoto, Japan

Professional Training and Employment 1990 Resident, Dept. of Anesthesiology, Kyoto University Hospital, Kyoto, Japan 1991 – 1994 Anesthesiologist, Dept. of Anesthesia, Ohtsu Municipal Hospital, Shiga, Japan 1997 – 1999 Instructor, Dept. of Anesthesiology, Kyoto University Hospital, Kyoto, Japan 1999 – 2002 Postdoctoral Research Fellow, Vollum Institute, Oregon Health & Science University, Portland, Oregon 2002 – 2008 Assistant Professor, Section of Neurobiology and Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin 2008 – present Associate Professor, Department of Neuroscience and Waggoner Center for Alcohol and Addiction Research, University of Texas at Austin Memberships 1991 – 2002 Japan Society of Anesthesia 1999 – present Society for Neuroscience 2003 – present Research Society on Alcoholism 2006 – present The American Society for Pharmacology and Experimental Therapeutics 2010 – present International Basal Ganglia Society

Grants and Awards 1994 – 1997 Japan Scholarship Foundation Predoctoral Scholarship Cellular and molecular investigation of opioid receptors 1998 – 1999 Ministry of Education, Science and Culture of Japan Grant-in-Aid for Scientific Research Cellular and molecular mechanism of opioid tolerance 1999 – 2000 Uehara Memorial Foundation Postdoctoral Fellowship Opioid action on midbrain 2002 – 2003 Texas Commission on Alcohol and Drug Abuse Grant (PI: 10% effort) Alcohol action in the brain reward circuit 2003 – 2005 Alcoholic Beverage Medical Research Foundation Grant (PI: 10% effort) Alcohol action on ion channels in the brain reward circuit 2003 – 2008 NIH R01 DA015687 (PI: 35% effort) Calcium signaling in the reward circuit & drug addiction 2004 – 2009 NIH R01 AA014874 (Co-I: 5% effort) Mu receptors and ethanol/dopamine interactions 2007 – 2012 NIH R01 AA015521 (PI: 3.5-month effort) Alcohol action on neurons in the brain reward circuit 2009 – 2014 NIH R01 AA06399 (co-I: 1.2-month effort) Alcohol actions: molecular targets on brain proteins 2009 – 2015 NIH R01 DA015687 (PI: 3.5-month effort) Calcium signaling in the reward circuit and drug addiction 2012 – 2017 NIH P01 AA020683 (co-I: 0.6-month effort) Novel molecular and cellular approaches for alcoholism medication development 2013 – 2019 NIH R01 AA015521 (PI: 3.5-month effort) Alcohol action in the brain reward circuit

2019 – 2021 NIH R21 MH119253 (PI: 2.0-month effort) Dopamine timing-dependent plasticity in reward learning 2020 – 2025 NIH R01 MH122539 (PI: 1.0-month effort; pending) Experience-Dependent Regulation of Reward Learning in Mental Illness

Teaching – Organized courses Spring 2003 Molecular Basis of Drug Addiction (BIO381K) Fall 2003 – present Neurobiology of Disease (NEU365T) Fall 2009 – present Neurobiology of Disease (NEU385L): co-taught with Drs. Robert J. Buchanan and Zoltan Nadasdy at Seton Brain and Spine Institute

Teaching – Other activities Fall 2002 NEU382T (Principles of Neuroscience): Gave a 1.5-hr lecture Spring 2003 BIO101C (ICMB Undergraduate Seminar Course): Gave a 1-hr lecture Spring 2003 Neurobiology Journal Club: Supervised three 1-hr student presentations Fall 2003 NEU185 (Principles of Neuroscience): Supervised three 1-hr student presentations Spring 2005 BIO101C (ICMB Undergraduate Seminar Course): Gave a 1-hr lecture and organized a section called “The Plastic Brain”. Spring 2005 Neurobiology Journal Club: Supervised two 1-hr student presentation sessions Fall 2006 Neurobiology Journal Club: Supervised three 1-hr student presentation sessions Spring 2007 BIO381K/NEU394P (Career Development for ): Participated as a guest speaker in a 1-hr discussion session on “Tenure track” Fall 2009 BIO101C (ICMB Undergraduate Seminar Course): Gave a 1-hr lecture Spring 2010 BIO381K/NEU394P (Career Development for Neuroscientists): Gave a 1-hr lecture and supervised a discussion session on “Tenure track” NEU383T (Principles of Neuroscience II): Supervised a 3-hr discussion session on “Dopamine and reward” Spring 2011 NEU383T (Principles of Neuroscience II): Supervised a 3-hr discussion session on “Dopamine and reward” Fall 2011 BIO101C (ICMB Undergraduate Seminar Course): Gave a 1-hr lecture Fall 2011 NEU482T/BIO437 (Principles of Neuroscience I): Gave a 1.5-hr lecture on “Brain reward mechanisms” Spring 2012 BIO381K/NEU394P (Career Development for Neuroscientists): Gave a 1-hr lecture and supervised a discussion session on “Tenure track” Fall 2012 NEU482T/BIO437 (Principles of Neuroscience I): Supervised a 1.5-hr discussion session on “Dopamine in reward processing and addiction” Spring 2013 NEU383T (Principles of Neuroscience II): Supervised a 3-hr discussion session on “Mesolimbic system: Dopamine or GABA?” Spring 2013 BIO101C (ICMB Undergraduate Seminar Course): Gave a 1-hr lecture on “Pavlovian learning and addiction” Spring 2014 NEU383T (Principles of Neuroscience II): Supervised a 3-hr discussion session on “Dopamine neurons in reward learning and expectation” Fall 2014 PGS185D/NEU185D (Responsible Conduct of Science): Supervised a 1-hr discussion session on “Publications and Authorship” Fall 2014 BIO101C (ICMB Undergraduate Seminar Course): Gave a 1-hr lecture on “Pavlovian learning and addiction” Spring 2015 NEU383T (Principles of Neuroscience II): Supervised a 3-hr discussion session on “ in the amygdala and fear conditioning” Spring 2016 NEU383T (Principles of Neuroscience II): Supervised a 3-hr discussion session on “Synaptic plasticity in the amygdala and fear conditioning” Fall 2016 PGS185D/NEU185D (Responsible Conduct of Science): Supervised a 1-hr discussion session on “Publications and Authorship” Spring 2017 NEU383T (Principles of Neuroscience II): Supervised a 1.5-hr discussion session on “Reward learning" Fall 2017 PGS185D/NEU185D (Responsible Conduct of Science): Supervised a 1-hr discussion session on “Publications and Authorship” Spring 2018 NEU383T (Principles of Neuroscience II): Supervised a 1.5-hr discussion session on “Reward system" Fall 2018 PGS185D/NEU185D (Responsible Conduct of Science): Supervised a 1-hr discussion session on “Publications and Authorship” Spring 2019 NEU383T (Principles of Neuroscience II): Supervised a 1.5-hr discussion session on “Reward system" Fall 2019 PGS185D/NEU185D (Responsible Conduct of Science): Supervised a 1-hr discussion session on “Publications and Authorship” Spring 2020 NEU383T (Principles of Neuroscience II): Supervised a 1.5-hr discussion session on “Reward system"

Postdoctoral Fellows Supervised Takashi Okamoto: 4/2003 – 3/2005 (→ Anesthesiologist at University of Occupational and Environmental Health in Japan) Stephen Boehm: 9/2004 – 6/2005 (→ Assistant Professor of Psychology at Binghamton University) Kee-Chan Ahn: 12/2006 – 7/2010 (→ Postdoc at University of British Columbia, Canada) Huanmian Chen: 5/2007 – 9/2007 (→ Research Associate at Johns Hopkins University) Simona Perra: 10/2007 – 12/2010 (→ Research Associate at Emergo Group) Michael Clements: 2/2010 – 1/2012 (→ Lead System Designer at GE Healthcare in UK) Mickael Degoulet: 7/2010 – 4/2015 (→Postdoc at Institut de de la Timone, France) Linzy Hendrickson: 5/2011 – 4/2013 (→ Medical Science Liaison at Marine Polymer Technologies) Swapna Immani: 7/2011 – 6/2015 (→ Research Associate at UT Austin) Jorge Tovar-Diaz: 1/2012 – 8/2017 (→ Research Associate at Universidad Católica del Norte, Chile) Jason Cook: 3/2014 – 1/2017 (→ Postdoc at NIEHS) Kevin Lominac: 9/2015 – 8/2017 (→ Technical Information Scientist at Jackson Laboratory) Claire Stelly: 1/2016 – 4/15/2016 (→ Postdoc at UT San Antonio) Sakthivel Govindaraj: 11/2019 – 7/2020 Saul Jaime: 8/2020 – present

Graduate Students Supervised Guohong Cui: 4/2003 – 4/2007 (Neuroscience; PhD awarded in 4/2007 → Postdoc at NIAAA → Principal Investigator at NIEHS) Mark Harnett: 5/2004 – 5/2009 (Neuroscience; PhD awarded in 5/2009 → Postdoc at Janelia Farm, Howard Hughes Medical Institute → Assistant Professor, Department of Brain and Cognitive Sciences and McGovern Institute at MIT) Matthew Sullivan: 4/2005 – 12/2008 (CMB; PhD awarded in 12/2008 → Associate at Austin Technology Incubator) Brian Bernier: 5/2006 – 6/2011 (Neuroscience; PhD awarded in 6/2011 → Postdoc at UT Austin) Leslie Whitaker: 9/2008 – 8/2012 (Neuroscience; PhD awarded in 8/2012 → Postdoc at NIDA) Claire Stelly: 5/2010 – 12/2015 (Neuroscience; PhD awarded in 12/2015 → Postdoc at UT Austin) Santiago Papini (10/2016 – present; primary mentor: Dr. Jasper A. Smits in Pyschology)

Rotating Graduate Students Guohong Cui: 11/2002 – 3/2003 (Neuroscience) Rosie Ramazani: 9/2003 – 12/2003 (Neuroscience) Mark Harnett: 1/2004 – 3/2004 (Neuroscience) Matthew Sullivan: 12/2004 – 3/2005 (CMB) Jon Theile: 3/2005 – 5/2005 (CMB) Gayathri Nattar Ranganathan: 9/2005 – 12/2005 (Neuroscience) Brian Bernier: 2/2006 – 5/2006 (Neuroscience) Jennifer Prowell: 11/2007 – 2/2008 (CMB) Leslie Ramsey: 5/2008 – 8/2008 (Neuroscience) Claire Stelly: 1/2010 – 5/2010 (Neuroscience) Lance Lepovitz: 6/2013 – 8/2013 (CMB) Matthew Pomrenze: 9/2013 – 12/2013 (Neuroscience) Brian Bondy: 9/2014 – 12/2014 (Neuroscience) David Haimes: 5/2015 – 8/2015 (CMB)

Undergraduates Supervised Huay-ying Lo: 1/2003 – 12/2003 Naren Venkatesan: 1/2003 – 12/2003 Linda Yang: 8/2003 – 12/2003 WeiQuing Ng: 9/2003 – 12/2003 Erin Maresh: 5/2005 – 7/2005 Clifford Buckley: 5/2005 – 12/2005 Deniz Gerecci: 11/2007 – 5/2008 Priya Davar: 1/2008 – 3/2008 Arseny Bezprozvanny: 2/2008 – 1/2009 Wei Liu: 1/2009 – 4/2010 Kavita Thakkar: 2/2011 – 5/2011 Nishita Soneji: 5/2012 – 11/2012 Harsh Thakkar: 6/2013 – 5/2015 Grant Garwood: 3/2014 – 5/2016 Jenna Worrell: 3/2014 – 5/2015 Thu Nhi Le: 1/2015 – 5/2016 Andrew Wright: 3/2015 – 8/2015 Russell Kan: 5/2015 – 11/2016 Jeremiah Lee: 5/2015 – 8/2016 Kelsey Toungate: 5/2015 – 7/2016 Christina Nania: 5/2015 – 10/2016 Jeremiah Ling: 8/2015 – 7/2016 Trevor Hadley: 11/2015 – 7/2016 Minh Do: 7/2016 – 12/2017 Amy Shoga; 1/2017 – 4/2018 Justin Daih: 5/2017 – 3/2018 Sabrina Clemens: 5/2017 – 12/2017 Abbey Joseph: 10/2017 – 12/2019 Christopher Tran: 1/2018 – 8/2019 Kristen D’Angelo: 5/2018 – 12/2019 Jessica Lau: 8/2018 – 3/2020 Marilynn Gonzales: 5/2019 – present

International Visiting Student Supervised William Harris: 9/2018 – 12/2018 (3rd-year undergrad from Univ. of Nottingham, UK)

Summer Students Supervised Kunal Thakrar: 5/2008 – 7/2008 (medical student, Texas A&M Health Science Center) Adam Gordon: 5/2015 – 7/2015 (2nd year INS student)

Research Assistants Nicholas Gustafson: 4/2006 – 6/2006 Kavita Thakkar: 6/2011 – 5/2012 Bahram Pahlavan: 10/2016 – 6/2018 Cecilia Nelson: 11/2017 – 4/2018 Brent Kisby: 5/2018 – 9/2018 Clayton Payne: 10/2018 – 12/2019

International Visiting Researchers Hiroaki Yasumoto: 7/2019 – 12/2019 Ahmad Sleem: 9/2019 – 6/2020

PhD Thesis Committees Sangwook Jung: 8/2002 – 8/2005 (CMB; PhD awarded in 8/2005) Tao Zhang: 8/2003 – 7/2005 (Neuroscience; PhD awarded in 7/2005) William Doyon: 1/2004 – 11/2005 (Pharmacy; PhD awarded in 11/2005) Nicholas Sanderson: 11/2004 – 7/2007 (Neuroscience; PhD awarded in 7/2007) Kally O’Reilly: 12/2004 – 3/2008 (CMB; PhD awarded in 3/2008) Guohong Cui: 3/2005 – 4/2007 (Neuroscience; PhD awarded in 4/2007) Paul Mathews: 4/2005 – 11/2008 (Neuroscience; PhD awarded in 11/2008) Matthew Sullivan: 3/2006 – 12/2008 (CMB; PhD awarded in 12/2008) Mark Harnett: 7/2006 – 5/2009 (Neuroscience; PhD awarded in 5/2009) Anne Baumgartner: 8/2006 – 12/2010 (Biology at UTSA; PhD awarded in 12/2010) Martin Job: 8/2006 – 2/3009 (Pharmacy; PhD awarded in 3/2009) Elaina Howard: 9/2006 – 5/2009 (Neuroscience; PhD awarded in 5/2009) Sukant Khurana: 10/2006 – 11/2009 (Neuroscience; PhD awarded in 11/2009) Jennifer Carrillo: 11/2006 – 9/2010 (Neuroscience; PhD awarded in 9/2010) Jon Theile: 12/2006 – 10/2009 (CMB; PhD awarded in 10/2009) Nicole Riherd: 3/2007 – 8/2009 (CMB; PhD awarded in 8/2009) Brian Bernier: 9/2007 – 6/2011 (Neuroscience; PhD awarded in 6/2011) Brenda Houk: 11/2007 – 10/2011 (Neuroscience; PhD awarded in 10/2011) Zachary Jeanes: 5/2009 – 7/2012 (Pharmacy; PhD awarded in 7/2012) R. Brandon Goertz: 6/2009 – 5/2012 (Biology at UTSA; PhD awarded in 5/2012) Christina Schier: 8/2009 – 11/2012 (Pharmacy; PhD awarded in 11/2012) Leslie Ramsey: 12/2009 – 8/2012 (Neuroscience; PhD awarded in 8/2012) Armando Salinas: 1/2010 – 8/2013 (Pharmacy; PhD awarded in 8/2013) Ashley Crisp: 12/2010 – 4/2013 (CMB; PhD awarded in 5/2013) Stephen Topper: 3/2011 – 12/2013 (CMB; PhD awarded in 12/2013) Rafael Renteria: 8/2012 – 8/2015 (Neuroscience; PhD awarded in 8/2015) Claire Stelly: 8/2012 – 12/2015 (Neuroscience; PhD awarded in 12/2015) Kevin Bieri: 3/2014 – 4/2015 (Neuroscience; PhD awarded in 5/2015) Shannon Zandy: 4/2014 – 10/2016 (Pharmacy; PhD awarded in 10/2016) Joshua Russell: 8/2014 (CMB; PhD awarded in 8/2014) Alex Fanning: 10/2015 – 5/2019 (Neuroscience; PhD awarded in 5/2019) Lina Gonzalez: 4/2016 – 4/2019 (Psychology; PhD awarded in 4/2019) Moushumi Dey: 7/2016 – present (Neuroscience) Adam Gordon: 8/2017 – 11/2019 (Neuroscience; PhD awarded in 11/2019) Philip Lambeth: 11/2018 – present (Neuroscience) Emily Hilz: 11/2019 – present (Psychology) Michael Dugan:

Master’s Thesis Committees Jeremy Colonna: 8/2013 (Neuroscience)

Qualifying Exam Committees Michelle Dupre: 5/2005 (Neuroscience) Sukant Khurana: 5/2005 (Neuroscience) Andrew George: 5/2005 (Neuroscience) Nicole Riherd: 4/2006 (CMB) Elaina Howard: 5/2006 (Neuroscience) Jennifer Carrillo: 5/2006 (Neuroscience) Brenda Houck: 5/2006 (Neuroscience) Sung-Jae Kim: 4/2007 (CMB; served as a chair) Na Ye: 5/2007 (Neuroscience) Ann Clemens: 5/2008 (Neuroscience) Lindsay Dickey: 5/2009 (Neuroscience) Sachin Vaidya: 5/2009 (Neuroscience) Zachary Jeanes: 5/2009 (Pharmacy) Christina Schier: 8/2009 (Pharmacy) Jeremy Colonna: 5/2011 (Neuroscience) Rafael Renteria: 5/2011 (Neuroscience) Jeremy Colonna: 11/2012 (Neuroscience) Rayna Harris: 4/2014 (CMB) Alex Fanning: 5/2015 (Neuroscience) Matthew Harger: 8/2015 (CMB) Adam Gordon: 5/2016 (Neuroscience) Philip Lambeth: 5/2017 (Neuroscience) Tiahna Ontiveros: 9/2018 (Neuroscience)

Local Responsibilities/Activities 2003 – 2006 INS Seminar Committee 2006 – 2011 CMB International Admissions Committee 2007 – 2010 Secretary, Society for Neuroscience Austin Chapter 11/2007 Gave a neuroscience lecture to Austin Japanese community 3/2008 Gave a lecture to “” (a club formed by UT undergraduates interested in neuroscience) 5/2008 CMB Responsible Conduct of Research Workshop: participated as a small group discussion leader 1/2010 Post Tenure Review Committee 2/2010 Gave a neuroscience lecture to students (K-9) at Austin Japanese School 2011 – 2016 Chair, INS Progressions Committee 1/2011 Post Tenure Review Committee 2/2012 Gave a lecture to TriBeta (biological honors society at UT) 2012 – 2014 UT Recreational Sports Committee 11/2012 Gave a lecture to Japan Business Association in Texas (representing 6 major cities in Texas) 10/2013 Gave a lecture to JASGA (Japan-America Society of Greater Austin) 2014 CMB International Admissions Committee 2015 Department of Neuroscience Faculty Annual Review/Workload Committee 04/2019 Gave a lecture to “Synapse” (a club formed by UT undergraduates interested in neuroscience) 04/2019 Judge, CNS Undergraduate Research Forum 08/2019 – Consultant on R21DA049539 (Isradipine and Virtual Reality Cue Exposure for Smoking Cessation) 10/2019 Gave a lecture to “Synapse” (a club formed by UT undergraduates interested in neuroscience)

Other Responsibilities/Activities 8/2002 Reviewer, US Army Congressionally Directed Medical Research Program 2/2005 Reviewer, NIH, Neurobiology of Motivated Behavior Study Section (IFCN-1) 8/2006 Reviewer, NSF Career Development Award 5/2007 Reviewer, NIH, Neurobiology of Motivated Behavior Study Section (NMB) 2006 – present Participant/organizer, “Dopamine club”: a biannual scientific meeting with Drs. Charles Wilson and Carlos Paladini at UT San Antonio 2006 – present Editorial Advisory Board: Journal of Pharmacology and Experimental Therapeutics 2006 – 2011 Scientific Advisory Committee: Specialized Neuroscience Research Program (SNRP) at UT San Antonio 10/2007 Reviewer, Parkinson’s Disease Society Project Grant 2/2008 Panelist, Hereditary Disease Foundation Workshop (“Calcium in ”) 6/2008 Reviewer, NSF Grant 3/2009 Reviewer, NSF Grant 3/2009 Reviewer, Medical Research Council (UK) Grant 4/2009 Reviewer, Research Grants Council of Hong Kong Grant 9/2010 Reviewer, NIH, Special Emphasis Panel for PPG (ZRG1 IFCN-H (40) P) 9/2010 Reviewer, Neurological Foundation of New Zealand Grant 2010 – present Review Editor, Frontiers in Addictive Disorders and Behavioral Dyscontrol 11/2010 Named “Top Reviewer 2009–2010” for 3/2011 Reviewer, NIH, Special Emphasis Panel for PPG (ZRG1 MDCN-F (50) P) 3/2012 Reviewer, NIH, Special Emphasis Panel for R01/R21 (ZRG1 ETTN-B (02) M) 4/2012 Reviewer, NIH, Special Emphasis Panel for PPG (ZRG1 MDCN-F (50) P) 5/2013 Reviewer, VA, Special Emphasis Panel Neurobiology A (NURA) 8/2013 Reviewer, Michael J. Fox Foundation for Parkinson’s Research (MJFF), Rapid Response Innovation Awards Program 11/2013 Reviewer, VA, Special Emphasis Panel Neurobiology A (NURA) 11/2013 Reviewer, Medical Research Council (UK) Grant 2/2014 Discussion Leader, Gordon Research Conference: Alcohol & the Nervous System 6/2014 Reviewer, NIH, Fellowship Study Section (F02A) 11/2014 Reviewer, Swiss National Science Foundation Grant 12/2014 Reviewer, VA, Special Emphasis Panel Neurobiology A (NURA) 02/2015 Reviewer, NIH, Special Emphasis Panel for R01/R21 (ZRG1 IFCN-Z (02) M) 05/2015 Reviewer, VA, Special Emphasis Panel Neurobiology A (NURA) 05/2015 Reviewer, French National Research Agency (ANR) Grant 11/2015 French National Research Agency (ANR), Pre-proposal Evaluation Panel 04/2016 Reviewer, UT Austin CNS Catalyst Grant 07/2016 Reviewer, NIH, Small Business Panel (ETTN-L (11)) 11/2016 Reviewer, Brain Research Foundation Seed Grant UT internal competition 12/2016 Reviewer, Swiss National Science Foundation Grant 11/2017 Reviewer, NIH, Special Emphasis Panel for F32/K22 (ZNS1 SRB-M (04)) 12/2017 Reviewer, Swiss National Science Foundation Grant 07/2018 Reviewer, French National Research Agency (ANR) Grant 11/2018 Reviewer, Brain Research Foundation Seed Grant UT internal competition 6/2019 Reviewer, NIH, Neurobiology of Learning and Memory Study Section (LAM) 3/2020 Reviewer, NIH, Special Emphasis Panel for R01/R21 (ZRG1 IFCN-E (02) M)

Ad Hoc Reviewer (2002 – present): Addiction Biology Alcohol Alcoholism: Clinical and Experimental Research American Journal of Biochemical Pharmacology Biological BMC Neuroscience Brain Research Cell Cellular and Molecular Life Sciences Cell Reports Current Biology eLife European Journal of Neuroscience European Journal of Pharmacology Frontiers in Cellular Neuroscience Frontiers in Neuroscience Frontiers in Psychiatry Journal of Cell Science Journal of Journal of Journal of Neuroscience Journal of Neuroscience Methods Journal of Pharmacology and Experimental Therapeutics Journal of Physiology Journal of Psychiatry and Neuroscience Molecular Interventions Molecular and Cellular Neuroscience Nature Communications Nature Reviews Neuroscience Neural Plasticity Neurobiology of Disease and Neuropharmacology Neuropsychopharmacology Neuroscience Pflugers Archiv: European Journal of Physiology Plos ONE Scholarpedia Scientific Reports Synapse Trends in Neurosciences

Seminars 3/2003 UT Institute for Neuroscience Annual Symposium “Glutamate-induced inhibition of dopamine neurons” 5/2005 UT Neurobiology Seminar “Alcoholic story of pacemaker currents in dopamine neurons” 1/2006 UT Pharmacy Seminar “How does alcohol boost brain dopamine signal?” 2/2006 Morehouse School of Medicine Neuroscience Institute Seminar “How does alcohol boost brain dopamine signal?” 3/2006 UTSA Neurobiology Seminar “How does alcohol boost brain dopamine signal?” 1/2007 Winter Conference on Brain Research “Burst-induced Ca2+ signals in dopamine neurons: Regulation, plasticity & amphetamine” 3/2007 Baylor College of Medicine Neuroscience Seminar “Ca2+ signals in dopamine neurons: Regulation, synaptic plasticity & amphetamine” 7/2007 Research Society on Alcoholism Symposium “Ethanol action on tonic and phasic dopamine signals” 8/2007 UT Neurobiology Seminar “DANs and TANs: Two key players in the central dopaminergic system” 4/2009 NIDA Intramural Research Seminar “Burst timing-dependent synaptic plasticity of NMDA receptors in dopamine neurons: A cellular form of Pavlovian learning?” 4/2009 NIAAA Intramural Research Seminar “Burst timing-dependent synaptic plasticity of NMDA receptors in dopamine neurons: A cellular form of Pavlovian learning?” 1/2010 Winter Conference on Brain Research “Dopamine neuron plasticity in Pavlovian learning and addiction” 3/2010 University of New Mexico Neuroscience Seminar “Dopamine neuron plasticity in Pavlovian learning and addiction” 4/2010 University of Tennessee Health Science Center Neuroscience Seminar “Dopamine neuron plasticity in Pavlovian learning and addiction” 4/2011 Northwestern University Department of Physiology Seminar “Synaptic plasticity and metaplasticity in dopamine neurons: Potential roles in Pavlovian learning and addiction” 5/2011 International Congress on Alcoholism and Stress, Volterra, Italy “Ethanol experience enhances synaptic plasticity of NMDA receptors in the ventral tegmental area” 10/2011 UT Behavioral Neuroscience Seminar “Synaptic plasticity and metaplasticity in mesolimbic dopamine neurons: From brain slice to behaving animals” 11/2011 Mini-symposium: Society for Neuroscience Annual Meeting “NMDA receptor metaplasticity in the VTA and drug addiction” 3/2012 UCSF Gallo Center Seminar "Calcium signaling in the mesostriatal circuit: Dopamine neurons vs. striatal spiny neurons" 4/2012 Georgia State University Biology Seminar "The impact of early life experience on dopamine neuron activity and plasticity: Drug, social isolation, and junk food" 6/2012 Research Society on Alcoholism Symposium “Tonic and phasic dopamine in alcoholism” 9/2012 International Society for Biomedical Research on Alcoholism Symposium, Sapporo, Japan “VTA plasticity and metaplasticity in alcohol and psychostimulant addiction” 5/2013 Congress Dopamine 2013, Alghero, Italy “Dopamine neuron plasticity in alcoholism/addiction: Drug, stress & junk food” 6/2013 Research Society on Alcoholism Symposium “Synaptic plasticity and metaplasticity in VTA dopamine neurons: Drug, stress & junk food” 3/2014 UT Health Science Center at San Antonio Physiology Seminar “Can antihypertensives treat addiction?” 3/2014 University of North Carolina Center of Alcohol Studies Seminar “Can antihypertensives treat addiction?: L-type calcium channel blockade in the VTA extinguishes drug-cue memory” 4/2014 UT Austin Neuroscience Seminar “Can antihypertensives treat addiction?: L-type calcium channel blockade disrupts drug-cue memory” 5/2014 Alcoholism and Stress Conference, Volterra, Italy “Food and alcohol: Common neuroadaptations in the VTA” 5/2014 Japanese Society of Anesthesiologists Annual Meeting “How does the brain become addicted?” 6/2015 NIDA Intramural Research Seminar “Antihypertensive medication treats addiction: Disruption of drug-cue memory” 1/2016 Winter Conference on Brain Research “Dopamine regulation of Ca2+ signaling in the nucleus accumbens: Timing matters!” 6/2016 Research Society on Alcoholism Symposium “Drug experience makes dopamine neurons better teachers” 10/2016 UT Austin Institute for Mental Health Research Lunch “Antihypertensive medication treats addiction: Disruption of drug-cue memory (at least in rats...)” 10/2016 UTSA Neuroscience Symposium 2016 - Dopamine Neurons & Motivated Behavior “Synaptic plasticity in the dopamine circuit: Does timing matter?” 11/2016 OHSU Vollum Institute Seminar “Calcium signaling in mesolimbic dopamine circuit: Does timing matter?” 1/2017 Winter Conference on Brain Research “Food and alcohol: Common & differential neuroadaptations in the VTA” 3/2017 International Basal Ganglia Society (IBAGS) 2017 “Calcium regulation of neuronal activity and plasticity in the mesolimbic system” 9/2017 IUPUI Neuroscience Seminar “Learning to be addicted: Impact of daily life experience” 7/2018 JTW Neuroscience Retreat at Vollum Institute “Ca ⇔ DA” 10/2019 UT Behavioral Neuroscience Seminar “Stress / amphetamine / exercise: Aberrant reward learning revealed and relieved”

Bibliography

Research Articles

1. Papini S, Young CC, Gebhardt CS, Perrone A, Morikawa H, Otto MW, Roache JD, Smits AJ (2020) Isradipine enhancement of virtual reality cue exposure for smoking cessation: Rationale and study protocol for a double-blind randomized controlled trial. Contemporary Clinical Trials 94:106013.

2. Pomrenze MB, Tovar-Diaz J, Blasio A, Maiya R, Giovanetti SM, Lei K, Morikawa H, Hopf FW, Messing RO (2019) A corticotropin releasing factor network in the extended amygdala for anxiety. J Neurosci 39:1030-1043.

3. Tovar-Diaz J, Pomrenze MB, Kan R, Pahlavan B, Morikawa H (2018) Cooperative CRF and α1 adrenergic signaling in the VTA promotes NMDA plasticity and drives social stress enhancement of cocaine conditioning. Cell Reports 22:2756-2766.

4. Cook JB, Hendrickson LM, Garwood GM, Toungate KM, Nania CV, Morikawa H (2017) Junk food diet-induced obesity increases D2 receptor autoinhibition in the ventral tegmental area and reduces ethanol drinking. PLoS One 12:e0183685.

5. Ponomarev I, Stelly CE, Morikawa H, Blednov YA, Mayfield RD, Harris RA (2017) Mechanistic insights into epigenetic modulation of ethanol consumption. Alcohol 60:95-101.

6. Stelly CE, Pomrenze MB, Cook JB, Morikawa H (2016) Repeated social defeat stress enhances glutamatergic synaptic plasticity in the VTA and cocaine place conditioning. eLife 5:e15448.

7. Swapna I, Bondy B, Morikawa H (2016) Differential dopamine regulation of Ca2+ signaling and its timing dependence in the nucleus accumbens. Cell Reports 15:563-573.

8. Degoulet M, Stelly CE, Ahn KC, Morikawa H (2016) L-type Ca2+ channel blockade with antihypertensive medication disrupts VTA synaptic plasticity and drug-associated contextual memory. Mol Psychiatry 21:394-402. [This study was featured in the following websites: Texas Science (http://news.utexas.edu/2015/06/23/medication-may-stop-drug-and-alcohol-addiction) UT News - Year in Review: Top Research News (http://news.utexas.edu/2015/12/21/year-in-review-top-research-news) Popular Science (http://www.popsci.com/blood-pressure-drug-helps-break-alcohol-and-cocaine-)]

9. Clements MA, Swapna I, Morikawa H (2013) Inositol 1,4,5-triphosphate drives glutamatergic and cholinergic inhibition selectively in spiny projection neurons in the striatum. J Neurosci 33:2697-2708.

10. Whitaker LR, Degoulet M, Morikawa H (2013) Social deprivation enhances VTA synaptic plasticity and drug-induced contextual learning. Neuron 77:335-345. [This study was featured in the following journals/websites: Nature (http://www.nature.com/nature/journal/v494/n7438/full/494405e.html) Cell (http://www.sciencedirect.com/science/article/pii/S0092867413001372) Texas Science (http://web5.cns.utexas.edu/news/2013/01/socially-isolated-rats-addiction/)]

11. Beatty JA, Sullivan MA, Morikawa H, Wilson CJ (2012) Complex autonomous firing patterns of striatal low-threshold spike interneurons. J Neurophysiol 108:771-781.

12. Blednov YA, Benavidez JM, Geil C, Perra S, Morikawa H, Harris RA (2011) Activation of inflammatory signaling by lipopolysaccharide produces a prolonged increase of voluntary alcohol intake in mice. Brain Behav Immun 25:S92-S105.

13. Bernier BE, Whitaker LR, Morikawa H (2011) Previous ethanol experience enhances synaptic plasticity of NMDA receptors in the ventral tegmental area. J Neurosci 31:5205-5212. [This study was featured in “This Week in The Journal” in J Neurosci (http://www.jneurosci.org/content/31/14/i.full) and also in the following websites: Scientific American (http://www.scientificamerican.com/article.cfm?id=mouse-study-suggests-why) Texas Science (http://web5.cns.utexas.edu/news/2011/04/alcohol-helps-the-brain-remember/)]

14. Perra S, Clements MA, Bernier BE, Morikawa H (2011) In vivo ethanol experience increases

D2 autoinhibition in the ventral tegmental area. Neuropsychopharmacology 36:993-1002.

15. Theile JW, Morikawa H, Gonzales RA, Morrisett RA (2011) GABAergic transmission modulates ethanol excitation of ventral tegmental area dopamine neurons. Neuroscience 172:94-103.

16. Ahn KC, Bernier BE, Harnett MT, Morikawa H (2010) IP3 receptor sensitization during in vivo amphetamine experience enhances NMDA receptor plasticity in dopamine neurons of the ventral tegmental area. J Neurosci 30:6689-6699.

17. Harnett MT, Bernier BE, Ahn KC, Morikawa H (2009) Burst timing-dependent plasticity of NMDA receptor-mediated transmission in midbrain dopamine neurons. Neuron 62:826-838.

18. Theile JW, Morikawa H, Gonzales RA, Morrisett RA (2009) Role of 5-HT2C receptors in Ca2+-dependent ethanol potentiation of GABA release onto ventral tegmental area dopamine neurons. J Pharmacol Exp Ther 329:625-633.

19. Sullivan MA, Chen H, Morikawa H (2008) Recurrent inhibitory network among striatal cholinergic interneurons. J Neurosci 28:8682-8690. (This article was featured in “This Week in The Journal”.)

20. Theile JW, Morikawa H, Gonzales RA, Morrisett RA (2008) Ethanol enhances GABAergic transmission onto dopamine neurons in the ventral tegmental area of the rat. Alcohol Clin Exp Res 32:1040-1048.

21. Cui G, Bernier BE, Harnett MT, Morikawa H (2007) Differential regulation of - and metabotropic glutamate receptor-induced Ca2+ signals by inositol 1,4,5-trisphosphate in dopamine neurons. J Neurosci 27:4776-4785.

22. Ponomarev I, Maiya R, Harnett MT, Schafer GL, Ryabinin AE, Blednov YA, Morikawa H, Boehm SL II, Homanics GE, Berman A, Lodowski KH, Bergeson SE, Harris RA (2006)

Transcriptional signatures of cellular plasticity in mice lacking the α1 subunit of GABAA receptors. J Neurosci 26:5673-5683.

23. Okamoto T, Harnett MT, Morikawa H (2006) Hyperpolarization-activated cation current (Ih) is an ethanol target in midbrain dopamine neurons of mice. J Neurophysiol 95:619-626. [This study was featured in the following editorial focus: Lupica CR, Brodie MS (2006) Queer currents, steady rhythms, and drunken DA neurons. J Neurophysiol 95:585-586.]

24. Cui G, Okamoto T, Morikawa H (2004) Spontaneous opening of T-type Ca2+ channels contributes to the irregular firing of dopamine neurons in neonatal rats. J Neurosci 24:11079-11087.

25. Paladini CA, Robinson S, Morikawa H, Williams JT, Palmiter R (2003) Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism. Proc Natl Acad Sci USA 100:2866-2871.

26. Morikawa H, Khodakhah K, Williams JT (2003) Two intracellular pathways mediate mGluR-induced Ca2+ mobilization in dopamine neurons. J Neurosci 23:149-157.

27. Shoda T, Fukuda K, Uga H, Mima H, Morikawa H (2001) Activation of µ-opioid receptor induces expression of c-fos and junB via mitogen-activated protein kinase cascade. Anesthesiology 95:983-989.

28. Paladini CA, Fiorillo CD, Morikawa H, Williams JT (2001) Amphetamine selectively blocks inhibitory glutamate transmission in dopamine neurons. Nat Neurosci 4:275-281.

29. Morikawa H, Manzoni OJ, Crabbe JC, Williams JT (2000) Regulation of central synaptic

transmission by 5-HT1B auto- and heteroreceptors. Mol Pharmacol 58:1271-1278.

30. Morikawa H, Imani F, Khodakhah K, Williams JT (2000) Inositol 1,4,5-triphosphate-evoked responses in midbrain dopamine neurons. J Neurosci 20:RC103.

31. Morikawa H, Mima H, Uga H, Shoda T, Fukuda K (1999) Opioid potentiation of N-type Ca2+ channel currents via pertussis toxin-sensitive G proteins in NG108-15 cells. Pflügers Arch 438:423-426.

32. Fukuda K, Shoda T, Morikawa H, Kato S, Mima H, Mori K (1998) Activation of

phospholipase A2 by the nociceptin receptor expressed in Chinese hamster ovary cells. J Neurochem 71:2186-2192.

33. Fukuda K, Kato S, Shoda T, Morikawa H, Mima H, Mori K (1998) Partial agonistic activity of naloxone on the opioid receptors expressed from complementary deoxyribonucleic acids in Chinese hamster ovary cells. Anesth Analg 87:450-455.

34. Morikawa H, Fukuda K, Mima H, Shoda T, Kato S, Mori K (1998) Nociceptin receptor-mediated Ca2+ channel inhibition and its desensitzation in NG108-15 cells. Eur J Pharmacol 351:247-252.

35. Morikawa H, Fukuda K, Mima H, Shoda T, Kato S, Mori K (1998) Tyrosine kinase inhibitors suppress N-type and T-type Ca2+ channel currents in NG108-15 cells. Pflügers Arch 436:127-132.

36. Kato S, Fukuda K, Morikawa H, Shoda T, Mima H, Mori K (1998) Adaptations to chronic agonist exposure of µ-opioid receptor-expressing Chinese hamster ovary cells. Eur J Pharmacol 19:221-228.

37. Morikawa H, Fukuda K, Mima H, Shoda T, Kato S, Mori K (1998) Desensitization and resensitization of δ-opioid receptor-mediated Ca2+ channel inhibition in NG108-15 cells. Br J Pharmacol 123:1111-1118.

38. Mima H, Morikawa H, Fukuda K, Kato S, Shoda T, Mori K (1997) Ca2+ channel inhibition by endomorphins via the cloned µ-opioid receptor expressed in NG108-15 cells. Eur J Pharmacol 340:R1-R2.

39. Fukuda K, Shoda T, Morikawa H, Kato S, Mori K (1997) Activation of mitogen-activated protein kinase by the nociceptin receptor expressed in Chinese hamster ovary cells. FEBS Lett 28:290-294.

40. Fukuda K, Kato S, Morikawa H, Shoda T, Mori K (1996) Functional coupling of the δ-, µ-, and κ-opioid receptors to mitogen-activated protein kinase and arachidonate release in Chinese hamster ovary cells. J Neurochem 67:1309-1316.

41. Morikawa H, Fukuda K, Kato S, Mori K, Higashida H (1995) Coupling of the cloned µ-opioid receptor with the ω-conotoxin-sensitive Ca2+ current in NG108-15 cells. J Neurochem 65:1403-1406.

Review Articles/Commentaries

1. Dobbs LK, Morikawa H (2020) Biasing Neurotensin Receptor Signaling to Arrest Psychostimulant Abuse. Cell 181:1205-1206.

2. Gantz S, Ford CP, Morikawa H, Williams JT (2018) The evolving understanding of dopamine neurons in the Substantia Nigra and Ventral Tegmental Area. Annu Rev Physiol 80:219-241.

3. Cui C, Noronha A, Morikawa H, Alvarez VA, Stuber GD, Szumlinski KK, Kash TL, Roberto M, Wilcox MV (2013) New insights on neurobiological mechanisms underlying alcohol addiction. Neuropharmacology 67:223-232.

4. Morikawa H, Paladini CA (2011) Dynamic regulation of midbrain dopamine neuron activity: Intrinsic, synaptic, and plasticity mechanisms. Neuroscience 198:95-111.

5. Morikawa H, Harris RA (2011) Small K channels: Big targets for treating alcoholism? Biol Psychiatry 69:614-615.

6. Morikawa H, Morrisett RA (2010) Ethanol action on dopaminergic neurons in the ventral tegmental area: Interaction with intrinsic ion channels and inputs. Int Rev Neurobiol 91:235-288.

Book Chapter

1. Whitaker LR, Hendrickson LM, Morikawa H (2014) Neural plasticity in the ventral tegmental area and alcohol addiction. In Neurobiology of Alcohol Dependence (Elsevier): Chapter 12 (p.227-249).

Clinical Case Reports

1. Morikawa H, Mima H, Fujita H, Mishima S (1995) Oxygen embolism due to hydrogen peroxide irrigation during cervical spinal surgery. Can J Anaesth 42:231-233.

2. Morikawa H, Hirota K, Kito K, Fujita H, Mishima S (1994) Re-expansion pulmonary oedema following removal of intrathoracic haematoma. Acta Anaesthesiol Scand 38:518-520.

Abstracts

1. Morikawa H (2017) Calcium regulation of neuronal activity and plasticity in the mesolimbic system. International Basal Ganglia Society (IBAGS) 2017

2. Morikawa H (2017) Food and alcohol: Common & differential neuroadaptations in the VTA. Winter Conference on Brain Research

3. Morikawa H (2016) Dopamine regulation of Ca2+ signaling in the nucleus accumbens: Timing matters! Winter Conference on Brain Research

4. Morikawa H (2016) Drug experience makes dopamine neurons better teachers. Research Society on Alcoholism Symposium

5. Cook JB, Hendrickson LM, Garwood GM, Toungate KM, Morikawa H (2015) Extended access to cafeteria diet reduces ethanol sensitivity of VTA dopamine neurons via enhanced D2 autoinhibition. Alcohol Gordon Conference.

6. Tovar-Diaz J, Pomrenze M, Morikawa H (2015) Stress acutely promotes calcium-dependent glutamatergic synaptic plasticity via differential actions of CRF and . Society for Neuroscience.

7. Cook JB, Hendrickson LM, Thakkar HB, Morikawa H (2014) Extended access to a highly palatable cafeteria-style diet reduces VTA dopamine neuron activity and ethanol consumption. Society for Neuroscience.

8. Stelly C, Degoulet M, Pomrenze MB, Morikawa H (2014) Chronic social stress persistently facilitates NMDAR-LTP induction mechanism in VTA dopaminergic neurons. Alcoholism and Stress Conference.

9. Morikawa H, Hendrickson LM, Pomrenze MB, Okamoto T, Bernier BE, Perra S (2014) Food and alcohol: Common neuroadaptations in the VTA. Alcoholism and Stress Conference.

10. Stelly C, Morikawa H (2013) Chronic social stress persistently facilitates NMDAR-LTP induction mechanism in VTA dopaminergic neurons. Society for Neuroscience.

11. Degoulet M, Stelly C, Ahn KC, Morikawa H (2013) L-type calcium channel blockade in the VTA disrupts cocaine-associated contextual memory. Society for Neuroscience.

12. Morikawa H (2013) How do adverse social experiences influence VTA synaptic plasticity and drug-induced contextual learning? Research Society on Alcoholism.

13. Morikawa H (2013) Dopamine neuron plasticity in alcoholism. Dopamine 2013.

14. Morikawa H (2012) Metaplasticity in the ventral tegmental area promotes alcohol- and psychostimulant-induced contextual learning. International Society for Biomedical Research on Alcoholism.

15. Degoulet M, Ahn KC, Morikawa H (2012) L-type calcium channels in the ventral tegmental area: a critical contribution to cocaine-associated contextual memory. Federation of European Neuroscience Societies.

16. Morikawa H (2012) How does repeated ethanol experience alter tonic and phasic activity of dopamine neurons? Research Society on Alcoholism.

17. Whitaker LR, Degoulet M, Morikawa H (2011) Social isolation during adolescence enhances a dopamine neuron learning mechanism. Gordon Research Conference.

18. Morikawa H (2011) NMDA receptor metaplasticity in the VTA and drug addiction. Society for Neuroscience.

2+ + 19. Clements MA, Morikawa H (2011) IP3-induced activation of Ca -sensitive K channels in striatal medium spiny neurons. Society for Neuroscience.

20. Degoulet M, Ahn KC, Morikawa H (2011) L-type voltage-gated calcium channels in the ventral tegmental area regulate acquisition and extinction of cocaine-induced place conditioning. Society for Neuroscience.

21. Bernier BE, Ramsey LA, Morikawa H (2011) Previous ethanol experience enhances synaptic plasticity of NMDA receptors in the ventral tegmental area. Winter Conference on Brain Research.

22. Morikawa H (2011) Previous ethanol experience enhances synaptic plasticity of NMDA receptors in the ventral tegmental areas: Interaction with CRF. International Congress on Alcoholism and Stress.

23. Beatty JA, Morikawa H, Wilson CJ (2010) Spontaneous activity of striatal low-threshold spike interneurons. Society for Neuroscience.

24. Ahn KC, Bernier BE, Harnett MT, Morikawa H (2010) NMDA receptor metaplasticity in VTA dopamine neurons promotes learning of environmental stimuli during psychostimulant experience. International Basal Ganglia Society.

25. Beatty JA, Morikawa H, Wilson CJ (2010) Spontaneous activity of striatal low-threshold spike interneurons. International Basal Ganglia Society.

26. Morikawa H (2007) Dopamine neuron plasticity in Pavlovian learning and addiction. Winter Conference on Brain Research.

27. Bernier BE, Morikawa H (2010) In vivo ethanol exposure enhances inositol triphosphate-mediated calcium signaling in ventral tegmental area dopamine neurons. Research Society on Alcoholism.

28. Bernier BE, Morikawa H (2009) In vivo ethanol exposure enhances inositol triphosphate-mediated calcium signaling in ventral tegmental area dopamine neurons. Society for Neuroscience.

29. Harnett MT, Ahn KC, Bernier BE, Morikawa H (2009) Burst timing-dependent plasticity of NMDA receptor-mediated transmission in dopamine neurons. International Narcotics Research Conference.

30. Perra S, Morikawa H (2009) Hypodopaminergic state during alcohol withdrawal: enhanced

D2 receptor-mediated autoinhibition of dopamine neurons. Research Society on Alcoholism.

31. Ahn KC, Bernier BE, Morikawa H (2008) Amphetamine conditioning enhances mGluR-dependent facilitation of burst-induced calcium signals in dopamine neurons. Society for Neuroscience.

32. Harnett MT, Morikawa H (2008) Burst timing-dependent plasticity of NMDA receptor-mediated synaptic transmission in midbrain dopamine neurons. Society for Neuroscience.

33. Theile JW, Morikawa H, Gonzales RA, Morrisett RA (2008) Role of extracellular and intracellular calcium in ethanol enhancement of GABAergic transmission onto VTA dopamine neurons. Research Society on Alcoholism.

34. Ahn KC, Harnett MT, Bernier BE, Morikawa H (2008) Metabotropic receptor-mediated facilitation of burst-induced Ca2+ signals in VTA dopamine neurons correlates with amphetamine-conditioned place preference. Canadian College of Neuropsychopharmacology.

35. Bernier BE, Cui G, Harnett MT, Morikawa H (2007) Ethanol action on metabotropic glutamate receptor-mediated pause in dopamine neurons. Society for Neuroscience.

36. Bernier BE, Cui G, Harnett MT, Morikawa H (2007) Ethanol action on mGluR-mediated pause in dopamine neurons. Research Society on Alcoholism.

37. Theile JW, Morikawa H, Gonzales RA, Morrisett RA (2007) Mechanisms underlying ethanol enhancement of GABAergic transmission on VTA dopamine neurons. Research Society on Alcoholism.

38. Morikawa H (2007) Burst-induced Ca2+ signals in dopamine neurons: Regulation, plasticity & amphetamine. Winter Conference on Brain Research.

39. Cui G, Harnett MT, Morikawa H (2006) Ca2+ store-dependent regulation of afterhyperpolarizations in midbrain dopamine neurons. Society for Neuroscience.

40. Harnett MT, Morikawa H (2006) Short- and long-term plasticity of NMDA receptor-mediated synaptic transmission in midbrain dopamine neurons. Society for Neuroscience.

41. Sullivan MA, Morikawa H (2006) Polysynaptic pause in striatal cholinergic interneurons. Society for Neuroscience.

42. Theile JW, Harnett MT, Morikawa H, Gonzales RA, Morrisett RA (2006) Low levels of ethanol directly enhance GABA release onto midbrain dopamine neurons. Research Society on Alcoholism.

43. Harnett MT, Morikawa H (2005) Active repolarization of synaptically-driven NMDA plateau potentials in midbrain dopamine neurons via Ca2+-induced Ca2+ release and SK channels. Society for Neuroscience.

44. Okamoto T, Morikawa H (2004) Ethanol enhancement of hyperpolarization-activated cation currents in midbrain dopamine neurons. Society for Neuroscience.

45. Cui C, Morikawa H (2004) Calcium influx through T-type calcium channels triggers spontaneous miniature outward currents in dopamine neurons of neonatal rats. Society for Neuroscience.

46. Okamoto T, Blednov YA, Morikawa H (2003) Ethanol stimulates G protein-gated K+ channels in dopamine neurons. Society for Neuroscience.

47. Cui G, Morikawa H (2003) Spontaneous outward currents in dopaminergic neurons of neonatal rats. Society for Neuroscience.

48. Morikawa H, Blednov YA (2003) Ethanol enhancement of G protein-gated K+ channels in dopamine neurons. Research Society on Alcoholism.

49. Morikawa H, Williams JT (2001) IP3-independent release of release of calcium mediated by mGluRs in midbrain dopamine neurons. Society for Neuroscience.

50. Imani F, Morikawa H, Williams JT, Khodakhah K (2001) Inositol 1,4,5-triphosphate evoked responses in dopaminergic cells of ventral midbrain. Biophysical Society.

51. Morikawa H, Imani F, Khodakhah K, Williams JT (2000) InsP3-evoked responses in midbrain dopamine neurons. Society for Neuroscience.