Supplementary Figure S1. TMEM2 Protein Expression Levels in Human

Supplementary Figure S1. TMEM2 protein expression levels in human cancer A SOX4 BDTMEM2 C SOX4 TMEM2 **** **** **** *** 6.0 3.0 1.5 2.0 4.0 2.0 1.0 1.0 2.0 1.0 0.5 Relative expression Relative Relative expression Relative expression Relative expression 0.0 0.0 0.0 0.0

MDA-LM2 MDA-LM2 CN34-LM2 CN34-LM2 MDA-parental MDA-parental CN34-parental CN34-parental EGMDA-LM2 FHMDA-LM2 CN34-LM1A CN34-LM1A SOX4 TMEM2 SOX4 TMEM2

1.0 1.0 1.0 1.0 **** **** **** **** **** **** 0.5 0.5 **** 0.5 0.5

**** Relative expression Relative expression Relative expression Relative expression 0.0 0.0 0.0 0.0

SOX4 SOX4 SOX4 SOX4 SOX4 SOX4 SOX4 SOX4 1 2 1 2 1 2 1 2 siControlsi si siControlsi si siControlsi si siControlsi si I

SOX4 SOX4 siCTRL si 1 si 2 Sox4 50

Gapdh

Supplementary Figure S2. SOX4 is necessary and sufficient for regulation of TMEM2. TMEM2TMEM2 1 2 shCTRLsh sh Tmem2 250 150

100

Gapdh

Supplementary Figure S3. Western blot quantification of Tmem2 in MDA-LM2 cells expressing shRNAs targeting TMEM2 or control shRNA. CN34-LM1A A B TMEM2 200 shCTRL 7 shTMEM2 X10 150 1.5 1.0 100 shCTRL ** 1.0 0.5

Normalized 50 lung photon flux lung photon 0.5 *** 0 Relative expression 0.0 0 1020304050 Days post-injection shTMEM2 shCTRL shTMEM2

Supplementary Figure S4. Knockdown of TMEM2 reduces lung colonization ability of CN34-LM1A cells. Supplementary Table S1. List of optimized primers used in qRT-PCR and ChIP- qPCR.

Primer name Primer sequences SOX4_Fwd 5’-GAAGGTGAAGTCCGGCAAC-3’ SOX4_Rev 5’-ACCGACCTTGTCTCCCTTCT-3’ TMEM2_Fwd 5’-TTCAGGGTGGTCAGAACAAGT-3’ TMEM2_Rev 5’-AAGCCTCTAATTGGGAACGTC-3’ TMEM2_pre_Fwd 5’-GTCCTCCTCCTTGTTGTGGA-3’ TMEM2_pre_Rev 5’-AAAATCGGACTTGACCAGGC-3’ 18S_Fwd 5’-GTAACCCGTTGAACCCCATT-3’ 18S_Rev 5’-CCATCCAATCGGTAGTAGCG-3’ GAPDH_Fwd 5’-AGCCACATCGCTCAGACAC-3’ GAPDH_Rev 5’-GCCCAATACGACCAAATCC-3’ #1_Fwd 5’-ACATTGACCCTCCCATACCC-3’ #1_Rev 5’-GAGAAACAGCAGCCACACTC-3’ #2_Fwd 5’-ATGTGTGGTGAGGGGTTAGG-3’ #2_Rev 5’-TGCGAAGACTTTGAGGTGGA-3’ #3_Fwd 5’-ACCCCAAGAGCACTCCATTT-3’ #3_Rev 5’-ATGCTGTAAGGGGCTTCACT-3’ #4_Fwd 5’-AAGGAGAGATGACAGGAGGC-3’ #4_Rev 5’-ACACTGGCTAAGACCTGAGAC-3’ #5_Fwd 5’-GCATCTGGTTGTGCTAGTGAG-3’ #5_Rev 5’-TGTACAGCCTGCAGAATCGA-3’ #6_Fwd 5’-AAAATCATGCAGGGGAGGGA-3’ #6_Rev 5’-GAGGTGAGGTCTGATGGGAG-3’ #7_Fwd 5’-CTCCCATCAGACCTCACCTC-3’ #7_Rev 5’-TTCATCCTGGGACGTGACAT-3’ #8_Fwd 5’-GTCATGTCACGTCCCAGGAT-3’ #8_Rev 5’-AGGCTCTGAGACACTGACAA-3’ #9_Fwd 5’-TGTCAGTGTCTCAGAGCCTG-3’ #9_Rev 5’-CGTTGAAGTGAGCCAAGACC-3’ #10_Fwd 5’-GGTCTTGGCTCACTTCAACG-3’ #10_Rev 5’-TAGTGGGGAACAGGGGTGTA-3’ #11_Fwd 5’-GTCTCCTACACCCCTGTTCC-3’ #11_Rev 5’-AATAGCAATTAGGCCAGGCG-3’ #12_Fwd 5’-CGCCTGGCCTAATTGCTATT-3’ #12_Rev 5’-TTAGCACACACAGAGGAGGG-3’ #13_Fwd 5’-TCCCCAACTCAAGAAGACCC-3’ #13_Rev 5’-CTTCTGGGATAGGCAGGGAG-3’ #14_Fwd 5’-AAAACCTTTCCTCCCTGCCT-3’ #14_Rev 5’-CGTCGCGCAATCTACTGAAT-3’ #15_Fwd 5’-CTAGTGACAGCTGCAGGACT-3’ #15_Rev 5’-GTAGATTGCGCGACGTCTG-3’ #16_Fwd 5’-CTCAGAGCGGCGTTTTGG-3’ #16_Rev 5’-TCTCAGCGCTGTCAGAAGAA-3’ #17_Fwd 5’-CTGGTACTGCGCCTGTCA-3’ #17_Rev 5’-ATATTTATTCCGGCCTGCGAG-3’ #18_Fwd 5’-TCCTTTCCCGGTTTCATCTCTG-3’ #18_Rev 5’-GCAAAGCACATTCCATCAACCT-3’ #19_Fwd 5’-ATTCCCAGCTTTTCTCTGCAGA-3’ #19_Rev 5’-AATTCAAGTGAGCTGTTTCCGC-3’ #20_Fwd 5’-CATACTGTGGTTGTGGGTCTGA-3’ #20_Rev 5’-GAAGACAGATTTCCAGTTCCGC-3’ #21_Fwd 5’-ATTAGAGGATCAGTTTGGGCGG-3’ #21_Rev 5’-TCTATTTCCCTGTCCACACACA-3’

Supplementary Table S2. List of 100 genes that were significantly upregulated in MDA-LM2 relative to MDA-parental as well as upregulated in CN34-LM1A relative to CN34-parental.

MDA-LM2 / MDA-parental CN34-LM1A / CN34-parental

SYMBOL fold_change p_value fold_change p_value ADAMTS17 4.389266902 0.0002 1.768928824 0.000845972 ADAMTS7 5.755215699 0.0002 1.969304224 1.06784E-06 AKAP13 1.751326414 0.00025 1.345031537 5.47401E-07 ALDH3A1 11.45376497 0.0001 103.7264489 9.07894E-09 ALDH3A2 1.844933736 0.00005 2.301891766 0 ALDOC 4.499578928 0.0007 1.334288833 0.00486621 ARHGAP26 1.762322552 0.00025 1.176665294 0.0153076 ARHGEF2 1.650924335 0.0007 1.257759425 0.000327173 BCAR3 1.57734364 0.0009 1.148664118 0.00869422 C6orf174,KIAA0408 1.973341985 0.0014 3.253313834 0 CADM1 5.448427855 0.00005 452.8313404 8.86749E-10 CELSR1 5.17801807 0.00005 2.231184783 0 COL13A1 2.090271004 0.00005 2.14244772 0 COL4A2 1.750508419 0.0003 1.746937507 0 COL4A5 2.708285816 0.00005 1.561045945 8.04219E-10 COL5A1 1.670531284 0.00015 2.059765359 0 COL6A1 6.544622597 0.00005 1.289673614 8.53252E-05 COL6A2 6.858247647 0.00005 1.849766285 9.11653E-11 DCLK1 11.69443292 0.00005 41.11805165 0 DOCK10 1.775462636 0.0015 14.36284856 0 DUSP4 1.621568535 0.0011 1.290674314 2.62376E-07 DZIP1 3.334198507 0.00055 67.88966212 0 ENG 22.98944926 0.00005 3.638137325 1.01083E-07 EREG 5.149991317 0.00005 2.566869587 0 FBLN1 5.694226972 0.00005 1.790284662 5.67763E-06 FBXL7 26.40300077 0.00035 674.2267232 8.88178E-16 FIBCD1 6.397773865 0.00115 2.716426478 9.30498E-05 FKBP10 347.9388583 0.0011 78.95233341 0 FLRT2 2.125555604 0.0001 3.1272618 0 FSCN1 3.016509237 0.00005 3.260131143 0 FZD8 3.241900921 0.00005 5.716808642 2.774E-11 GALNT14 5.18627965 0.00045 #VALUE! 7.38485E-26 GPR158 25.74535039 0.00005 23.30552326 0 IGF1R 1.873005323 0.00005 2.023047228 0 IGF2BP3 1.643170288 0.00125 1.675326168 0 IL1B 9.561321292 0.00045 5.21808339 8.93063E-13 INHBB 7.999057375 0.00005 6.084294559 0 ITGA6 2.161061306 0.00005 1.282941155 8.33886E-06 ITGB4 3.716719983 0.00005 4.939208942 0 KISS1 3.697320223 0.0006 4.117475313 0 KLF9 2.370662027 0.0005 1.388369907 1.76317E-08 LAMA4 7.486959758 0.00005 18.97923582 0 LAMA5 4.285192456 0.00005 1.277970913 3.09139E-06 LAPTM5 2.604813352 0.00005 1.258447473 2.12399E-06 LDOC1 2.351628227 0.0002 3.477233623 0 LEPREL4 5.448503387 0.00005 1.648243052 6.06772E-07 LINC00341 2.87998241 0.00065 1.978033692 7.363E-12 LOC100127888 17.68960588 0.00005 4.822930431 0 LOC339535 13.02038317 0.00015 4.767292019 0 LRRCC1 1.755170277 0.0015 1.34916893 0.000022414 MMP1 2.425496336 0.00005 151.9339006 0 MRPS11 1.712289925 0.0015 1.18609289 0.0153157 NMNAT2 1.884206388 0.0011 17.02815237 0 NQO1 1.884589094 0.00005 2.317918756 0 NUP210 3.678633631 0.00005 1.542863041 9.53506E-11 ODZ1 24.4108394 0.00005 59.61361679 0 ODZ3 1.948763477 0.00005 6.035402553 0 PARM1 2.664768121 0.00075 2.037118634 9.59908E-05 PCDH20 7.769436678 0.0013 8.567949638 0 PDGFA 3.133576035 0.00005 2.744779013 0 PEG10 1.593889926 0.00155 2.943657865 0 PHGDH 6.93713519 0.00005 3.162794892 0 PHIP 1.768937407 0.0002 1.270180036 1.27863E-06 PHLDA2 2.194770363 0.00005 1.503132305 6.42647E-08 PIK3CG 7.325767934 0.00055 66.5630668 6.88338E-15 PLCB1 101.7221465 0.00015 43.75967141 0 PLXNA2 2.01084238 0.00005 2.475929096 0 POU2F2 2.178869816 0.0002 1.68507406 0.00254664 POU3F2 8.952930581 0.00075 70.58745983 0 PPP2R2C 2.892486047 0.00005 1.800383191 4.57406E-08 PTK7 1.985646767 0.00005 1.405629135 2.93714E-10 PXDN 1.997101974 0.00005 4.487338447 0 QPCT 3.458820152 0.00005 1.384030753 0.00155481 RAP1GAP2 2.64485751 0.00005 4.933426448 0 RASGRF1 2.089807418 0.00065 3.071854748 0 ROBO1 2.175293396 0.00005 140.1142618 0 RORA 3.718059866 0.0003 19.1189316 0 SASH1 1.738197481 0.0007 1.46433841 6.93088E-11 SDC1 1.619041538 0.00145 1.800149843 0 SEL1L3 3.644775615 0.00005 2.66983392 0 SEMA3D 2.932457095 0.00015 7.252910267 0 SEMA4B 2.158785646 0.00005 1.377938978 9.84579E-05 SERPINB5 7.136021688 0.0004 51.50747811 0.000131962 SERPINE2 2.38073988 0.00005 3.008720309 0 SH3TC2 2.721250939 0.00005 2.292640263 0 SHISA3 3.336348514 0.00025 5.235945207 0 SLCO4A1 4.173390736 0.00005 1.515275373 0.00347006 SLIT2 1.724253625 0.00045 2.123965011 0 SOCS3 1.773133302 0.0015 2.745064408 0 SOX4 1.92576545 0.0008 3.969700045 0 SRGN 4.297685763 0.00005 1.798446197 0 ST6GAL1 3.894262136 0.0003 1.6318789 0.000143922 ST8SIA4 2.94857931 0.0001 1.687207017 0.000294438 TGFBI 2.600465684 0.00005 1.816703525 0 TMEM154 2.097048168 0.0004 1.63610008 2.34479E-12 TMEM2 1.686470403 0.0004 1.793044135 0 TTYH3 1.812892023 0.0003 1.241683945 0.00111094 WDR72 24.06759367 0.00005 82.12673279 0 ZIC2 3.16007763 0.00005 2.096423229 4.44089E-16 ZNF592 1.64789235 0.0011 1.203331385 0.00162136

Supplementary Table S3. List of 1356 genes that were significantly downregulated in the context of SOX4 knockdown relative to control MDA-LM2 cells.

MDA-LM2_siControl (avg) / MDA-LM2_siSOX4 (avg)

SYMBOL fold change p-value AARS 2.001786717 1.9679E-11 ABCA1 3.885147193 0 ABCC3 1.530430683 0.000339573 ABHD4 1.299715913 0.033824168 ABHD7 1.413565257 0.004629544 ABHD8 1.29239975 0.037739747 ABI1 1.528217143 0.000358762 ABLIM3 1.323089425 0.023491678 ABR 1.660244148 9.28073E-06 ACAA2 1.397616487 0.006319714 ACAD10 1.29814398 0.034635994 ACER3 1.287955944 0.040293541 ACOT7 1.656613531 1.03681E-05 ACSL5 1.348020676 0.015535506 ACVR1 1.421322503 0.003963754 ACVR1B 1.337918498 0.018426241 ADAM17 1.446127098 0.002371482 ADAM19 1.751648694 4.70154E-07 ADAM8 1.478304481 0.001171048 ADD3 1.404745321 0.005506316 ADM2 1.29215608 0.037876271 ADRA2C 1.316604261 0.026050128 ADRBK1 1.371086097 0.010356569 AFAP1 1.302935239 0.032210373 AFTPH 1.449911466 0.002187664 AGA 1.418534191 0.004192494 AGGF1 1.32428839 0.023042618 AGPAT9 1.419072932 0.004147399 AGR2 1.345739306 0.016151849 AHNAK 1.71780135 1.48177E-06 AHNAK2 1.596137715 6.02411E-05 AIFM2 1.311964602 0.028020197 AKAP13 1.35821188 0.013022653 AKR1B1 2.029075999 5.52036E-12 AKR1B10 4.074212334 0 AKR1B15 1.888254881 2.71154E-09 AKR1C2 2.962230879 0 AKR1C3 2.939345385 0 AKR1C4 3.599175383 0 ALAD 1.365284935 0.01149252 ALDH3A2 2.208918015 5.55112E-16 ALDH3B1 1.276180372 0.04774416 ALDOA 1.416272078 0.004386667 ALS2CR4 1.450969348 0.002138642 AMD1 1.50347334 0.000653682 AMMECR1 1.530766715 0.000336745 AMT 1.425763777 0.00362243 ANAPC11 1.412360845 0.00474142 ANGEL2 1.294286122 0.036696378 ANKHD1-EIF4EBP3 1.306156947 0.030659545 ANKRA2 1.632764044 2.11572E-05 ANKRD11 1.433817176 0.003070133 ANKS1A 1.57984703 9.41381E-05 ANO6 1.371671969 0.010247481 ANTXR2 1.279663947 0.045433246 ANXA1 1.292082124 0.037917788 ANXA10 1.387521421 0.007653112 ANXA11 1.295966917 0.035786704 ANXA7 1.40365072 0.00562483 AP3D1 1.309030474 0.029328982 AP3S1 1.330191296 0.020935801 APBB3 1.464353258 0.001598872 APPBP2 1.319467989 0.02489298 APTX 1.342590174 0.017036971 ARAP2 1.284575404 0.042328852 ARHGAP1 1.281231712 0.044423007 ARHGAP12 1.4724296 0.001336497 ARHGAP21 1.287027077 0.040844698 ARHGAP28 1.313870276 0.027196496 ARHGEF6 1.310636932 0.028606261 ARL2 1.339426143 0.017967709 ARL2BP 1.29574719 0.035904564 ARL4C 1.489468859 0.000907246 ARPC1A 1.302015924 0.032664592 ARSD 1.312355885 0.027849396 ARV1 1.288238358 0.040127169 ASB13 1.610161891 4.06377E-05 ASCC3 1.356180677 0.013493397 ASF1A 1.295138867 0.036232522 ASNS 1.925769322 5.68058E-10 ATG10 1.274674881 0.048771563 ATG4B 1.343050051 0.016905183 ATP2B1 1.375380063 0.009580014 ATP5G2 1.317058001 0.02586384 ATP6AP2 1.353656352 0.014098837 ATP6V0A1 1.563760139 0.000144625 ATP6V0D1 1.473724557 0.001298293 ATP6V0E1 1.354760673 0.013831152 ATP6V1E1 1.276158706 0.047758822 ATP7A 1.618558841 3.19713E-05 ATP9A 1.4533015 0.002034071 ATPBD4 1.535675373 0.000297851 ATPIF1 1.403177794 0.00567673 ATXN1L 1.440447472 0.00267367 ATXN7L3 1.282520699 0.043606035 AUH 1.409810943 0.004986264 AXUD1 1.313283155 0.02744809 B3GALT4 1.306703006 0.030402919 B3GNTL1 1.319392235 0.024923026 B4GALT3 1.313758316 0.027244324 B4GALT5 1.412834724 0.004697118 BACH1 1.277407402 0.046919671 BAIAP2L1 1.531727535 0.000328779 BAMBI 1.574572841 0.000108504 BAZ2B 1.635893158 1.92948E-05 BBX 1.325946669 0.022433458 BCL2L13 1.631673102 2.18457E-05 BCL3 1.618710799 3.18319E-05 BCL6 1.785230343 1.43086E-07 BCL7B 1.304242818 0.031573311 BHLHB2 1.497671327 0.000749536 BIK 1.382492536 0.008405426 BIRC3 1.309688362 0.029031195 BNIP3L 1.395786034 0.006545022 BPGM 1.290200916 0.038986372 BRMS1 1.299990178 0.03368414 BRP44L 1.448981501 0.002231597 BRPF3 1.391832498 0.007056042 BRWD1 1.452819866 0.002055279 BSDC1 1.468719641 0.001451706 BTBD2 2.081863567 4.2899E-13 BTN3A2 1.362773909 0.012016847 C10orf104 1.470008944 0.001410678 C10orf116 1.422302513 0.003886053 C10orf54 1.284434073 0.042415721 C10orf78 1.295953639 0.035793817 C10orf84 1.283275136 0.043133518 C10orf90 1.374217539 0.009785061 C11orf1 1.366009694 0.011344927 C11orf49 1.452809045 0.002055757 C11orf63 1.280327129 0.045003672 C11orf70 1.35755384 0.013173579 C11orf73 1.382980981 0.008329612 C11orf74 1.486958332 0.000961292 C12orf35 2.014769939 1.07944E-11 C12orf51 1.28431523 0.04248888 C14orf100 1.610955758 3.97318E-05 C14orf126 1.296140052 0.03569406 C14orf133 1.296603237 0.035447175 C14orf139 1.475632866 0.001243811 C14orf173 1.385651672 0.007925604 C14orf78 1.787977789 1.29526E-07 C15orf38 1.342488816 0.017066134 C16orf58 1.599567074 5.47564E-05 C16orf7 1.308894177 0.029390992 C17orf44 1.309746906 0.029004818 C17orf49 1.2798457 0.045315189 C17orf61 1.499401709 0.000719674 C17orf63 2.11960733 6.38378E-14 C17orf68 1.394806758 0.006668452 C17orf91 1.379705877 0.008849652 C19orf22 1.571775767 0.000116935 C19orf50 1.308747988 0.029457623 C1orf131 1.2962713 0.03562396 C1orf24 1.398518556 0.006211227 C1orf43 1.35444728 0.013906669 C1orf52 1.319534669 0.024866559 C1orf54 1.316306872 0.026172832 C1orf85 1.390744521 0.007202711 C1QTNF1 1.286943157 0.040894792 C20orf100 2.226025924 2.22045E-16 C20orf199 1.351096109 0.01473666 C20orf30 1.413158551 0.004667056 C21orf33 1.363703865 0.011820293 C21orf59 1.427624514 0.003487444 C2CD2 1.457286772 0.001866066 C2orf28 1.413522474 0.004633478 C2orf47 1.276480886 0.047541168 C3orf52 1.294114021 0.036790579 C3orf64 1.430956772 0.003256955 C4orf34 1.370634907 0.010441267 C4orf41 1.575541154 0.000105721 C5orf22 1.352350505 0.014421121 C6orf1 1.433534984 0.003088125 C6orf115 1.326401043 0.022268936 C6orf129 1.436660446 0.00289405 C6orf136 1.334569147 0.019480673 C6orf25 1.275289766 0.048349828 C6orf47 1.365290352 0.01149141 C6orf64 1.296992593 0.035240728 C7orf25 1.35112032 0.014730514 C7orf54 1.318864364 0.025133235 C8orf33 1.463302988 0.001636242 C8orf55 1.278278514 0.046341298 C9orf119 1.34343994 0.016794136 C9orf89 1.612808417 3.76915E-05 C9orf91 1.364608632 0.011631746 CA13 1.382224827 0.008447235 CADM1 2.095662304 2.15383E-13 CADPS2 1.299093546 0.034143698 CALB2 2.108617912 1.1191E-13 CAMKK2 1.313142104 0.027508821 CAMSAP1 1.413546003 0.004631314 CAPN2 1.432928003 0.003127147 CARS 1.357567136 0.013170514 CAST 1.504900734 0.000631901 CBLB 1.569650224 0.000123748 CBWD5 1.358098858 0.013048469 CC2D1B 1.327732578 0.02179266 CCDC106 1.577417103 0.000100519 CCDC47 1.300912191 0.033216894 CCDC6 1.343472163 0.016784987 CCDC78 1.308789314 0.029438774 CCDC90B 1.293237282 0.037273549 CCDC92 1.525001488 0.000388438 CCNC 1.312406604 0.027827321 CCNJL 1.334278326 0.0195746 CCNY 1.385047719 0.008015427 CD163L1 1.59049061 7.04162E-05 CD58 1.474003123 0.001290206 CD96 1.368100941 0.010928254 CDC14B 1.327768293 0.021780005 CDC40 1.274105217 0.049164901 CDCP1 1.395993575 0.006519124 CDK6 1.388656709 0.007491713 CDK7 1.514898039 0.000497161 CDKN1A 1.606893161 4.45773E-05 CDRT1 1.388825399 0.007467989 CDRT4 1.325592506 0.022562404 CDS1 1.361612681 0.012266257 CEBPD 1.920751738 7.02728E-10 CFDP1 1.305770686 0.030842153 CGGBP1 1.367598035 0.011027221 CGI-96 1.279785087 0.045354533 CHD2 1.2823581 0.043708418 CHEK1 1.373116359 0.009982812 CHFR 1.345077725 0.016334457 CHMP1A 1.387256704 0.007691183 CHMP1B 1.904637627 1.38092E-09 CHMP2A 1.331787933 0.020394787 CHMP2B 1.44087308 0.002649875 CHMP5 1.38901706 0.007441114 CHP 1.418245939 0.004216802 CICE 1.316733089 0.025997122 CISD1 1.360238859 0.012567109 CLASP2 1.425935529 0.003609777 CLCN3 1.474032582 0.001289354 CLCN7 1.537229259 0.000286438 CLDN7 1.442455412 0.002563076 CLEC16A 1.389648167 0.007353222 CLEC4D 1.325347616 0.022651931 CLIP1 1.322212824 0.02382464 CLIP4 1.332750538 0.020074372 CMAS 1.519085078 0.000449072 CMTM3 1.889373741 2.59042E-09 CNBP 1.337574648 0.018532203 COASY 1.375263943 0.009600325 COG2 1.376115395 0.009452264 COG3 1.341938609 0.017225193 COL18A1 1.297892434 0.034767379 COMMD2 1.311407504 0.028264884 COMMD6 1.347433345 0.01569222 COPB2 1.278974011 0.045883645 COPS7A 1.281224637 0.044427525 COQ6 1.28221035 0.04380162 COX17 1.384686734 0.008069541 COX5B 1.28844573 0.040005361 CPD 1.702247119 2.46847E-06 CPEB2 1.424768405 0.003696547 CPNE8 1.495603241 0.000786722 CPT2 1.411416705 0.004830798 CPVL 1.32708236 0.02202415 CPXM1 1.471377776 0.001368281 CREB5 1.323399589 0.023374809 CRTC3 1.390627534 0.00721864 CRY2 1.326463386 0.022246442 CRYZL1 1.50056748 0.000700178 CSDA 1.285534478 0.041743149 CSF2 1.451895755 0.002096533 CSF3 1.332989571 0.019995473 CSNK1G1 1.280928203 0.044617157 CSNK1G2 1.317032818 0.02587415 CSRP2BP 1.483675931 0.001036416 CSTF2T 1.284758005 0.042216828 CTBP1 1.281324896 0.044363535 CTBS 1.49974306 0.000713914 CTDP1 1.295201836 0.036198461 CTH 1.75162035 4.70616E-07 CTHRC1 1.276921603 0.047244722 CTNNA1 1.303541944 0.031913475 CTNS 1.402192352 0.005786245 CTSK 1.415937656 0.004416044 CTSL1 2.085866714 3.51608E-13 CUTL1 1.289666035 0.039294638 CXCL13 1.326561872 0.022210947 CXorf57 1.395904664 0.006530207 CXorf61 1.294519045 0.036569198 CYB561D1 1.463015609 0.001646605 CYP1B1 3.067174188 0 CYP27C1 1.327083806 0.022023633 CYP2C9 1.283761532 0.042831079 CYP4V2 1.501824455 0.000679703 DAAM1 1.490071638 0.000894692 DAB2 1.446029012 0.002376427 DAG1 1.280664162 0.044786615 DCAF7 1.329956407 0.021016408 DCP1A 1.354244225 0.013955787 DCUN1D4 1.351064995 0.014744562 DDIT4 1.481272969 0.001094786 DDX10 1.471399496 0.001367617 DEDD 1.417348575 0.004293283 DENND4A 1.393708422 0.006809334 DHRS7 1.552765248 0.00019269 DHX32 1.460244504 0.001749644 DIABLO 1.448746868 0.002242807 DNAL4 1.290310819 0.038923276 DNASE2 1.539701982 0.000269113 DNM1L 1.350515312 0.014884758 DPAGT1 1.304263026 0.031563548 DPH2 1.574324391 0.000109229 DPH3 1.415100573 0.004490351 DPY19L1 1.701362834 2.54031E-06 DSCR4 1.297522814 0.034961177 DSE 1.284074353 0.042637475 DSG2 1.757110672 3.8878E-07 DSTN 1.325184213 0.022711834 DUS4L 1.349704909 0.01509354 DUSP18 1.640741465 1.67134E-05 DUSP22 1.511524981 0.000539322 DUSP4 1.311260891 0.028329574 DYNC2LI1 1.29469806 0.036471699 DYNLRB1 1.413114019 0.00467118 DYNLT3 1.294312159 0.036682143 E2F7 1.986607194 3.93292E-11 EAF1 1.320710979 0.024404309 ECE2 1.349503489 0.01514582 ECH1 1.968737252 8.76809E-11 EDEM1 1.597155792 5.8561E-05 EDEM2 1.381260676 0.008599326 EDEM3 1.346661904 0.015900118 EEF1A1 1.275235635 0.048386837 EFNB2 1.374416788 0.009749647 EGFR 1.52484647 0.000389925 EHD1 1.354662474 0.013854777 EHD4 1.353461854 0.014146442 EI24 1.477582086 0.001190329 EIF2AK1 1.282860974 0.0433924 EIF2S2 1.587554511 7.63259E-05 EIF4EBP2 1.331236036 0.02058044 ELAVL1 1.286887495 0.040928046 ELF1 1.440255547 0.002684464 EMP1 1.456347678 0.001904477 ENTPD6 1.352663546 0.01434329 EP400 1.353448321 0.01414976 EPCAM 1.279957363 0.045242782 EPHX1 1.295397336 0.036092878 EPM2AIP1 1.341377661 0.017388658 EPN1 1.331116583 0.02062081 EPRS 1.393784138 0.006799538 EPS15 1.299112419 0.034133972 EREG 2.353098332 0 ERRFI1 1.918136901 7.84768E-10 ETV6 1.363623388 0.011837191 EVI5 1.279793787 0.045348884 EXOC2 1.280043922 0.045186717 EXOSC6 1.504847602 0.0006327 EXT2 1.439285347 0.00273963 F11R 1.516103777 0.000482845 F2RL1 1.806321147 6.60523E-08 F2RL2 1.814984522 4.78051E-08 FAH 1.411040742 0.004866806 FAHD1 1.534521977 0.000306594 FAM102A 2.418632835 0 FAM115C 1.276226608 0.047712883 FAM116A 1.837846401 2.00398E-08 FAM127C 1.346941823 0.015824411 FAM129B 1.661729973 8.86783E-06 FAM133A 1.406305532 0.005341226 FAM159B 1.295762294 0.035896452 FAM160B1 1.30822063 0.029699029 FAM162A 1.325499763 0.022596274 FAM164A 1.45272597 0.002059436 FAM171A1 1.731220032 9.45795E-07 FAM177A1 1.739676673 7.09774E-07 FAM189B 1.550489535 0.000204346 FAM18B2 1.325725567 0.022513885 FAM195B 1.445954686 0.00238018 FAM21C 1.341114378 0.017465837 FAM43A 1.567637152 0.000130542 FAM60A 1.277888028 0.046599848 FAM62B 1.290328512 0.038913127 FAM74A3 1.279938999 0.045254684 FAM84B 2.136466324 2.67564E-14 FASTK 1.30305154 0.032153284 FAT1 1.355645309 0.013619891 FBXL13 1.471728582 0.001357604 FBXL18 1.69969365 2.68143E-06 FBXO21 1.348762493 0.015339493 FBXO30 1.526596879 0.000373441 FBXO32 1.36705345 0.011135268 FBXO33 1.764777066 2.97083E-07 FBXO38 1.357587285 0.013165872 FBXO8 1.396263013 0.006485637 FBXW7 1.532239655 0.000324604 FERMT3 1.349769085 0.015076915 FKBP14 1.273310511 0.049717852 FKRP 1.500554521 0.000700392 FLAD1 1.43574007 0.002950026 FLJ20273 1.378718788 0.00901187 FLJ20444 1.299300253 0.034037299 FLJ35220 1.386919315 0.007739947 FLJ46363 1.311578458 0.02818961 FLRT2 1.301047971 0.033148538 FMO4 1.420140138 0.004059348 FNDC3B 1.48595148 0.000983787 FNTA 1.362503867 0.012074451 FOSB 1.284990151 0.042074757 FOXD4 1.298836082 0.034276607 FOXD4L1 1.315562745 0.026481981 FOXK1 1.564854456 0.000140512 FOXRED1 1.287135212 0.040780221 FRAP1 1.374583451 0.009720111 FRAT2 1.752190269 4.61405E-07 FRMD8 1.758296795 3.72996E-07 FSCN1 1.426707244 0.003553412 FTH1 1.400028447 0.006033327 FTHL11 1.505524685 0.000622593 FTHL12 1.408006727 0.005166248 FTHL2 1.361478728 0.012295314 FTHL3 1.359130088 0.012814555 FTHL7 1.336543965 0.018852936 FTHL8 1.533128472 0.000317477 FURIN 1.453302159 0.002034042 FVT1 1.364820164 0.011588043 FYCO1 1.275018198 0.048535729 FZD8 1.433526148 0.00308869 G6PD 1.525056287 0.000387914 GALC 1.311949672 0.028026732 GALE 1.34037439 0.017684325 GALK2 1.276909681 0.047252722 GARS 1.530571047 0.000338389 GATAD2A 1.306024892 0.030721874 GBE1 1.31846267 0.025294191 GBP2 1.411315677 0.004840451 GCLC 1.958842622 1.35829E-10 GCLM 1.346803034 0.015861909 GDF15 1.28094974 0.044603358 GEMIN8 1.355182741 0.013730008 GHITM 1.306317525 0.030583894 GJA1 1.304401997 0.031496474 GJB2 1.4441482 0.00247307 GLA 1.790209178 1.19435E-07 GLG1 1.323043059 0.023509191 GLRX 1.650692397 1.24058E-05 GLS 2.126679747 4.44089E-14 GMDS 1.305327247 0.031052902 GNG11 1.620104724 3.05799E-05 GNG2 1.320882295 0.024337593 GOLGA3 1.307038183 0.030246283 GOLGA7 1.35045773 0.01489951 GOLGA8B 1.328070079 0.021673315 GOLGB1 1.324013151 0.023145062 GOLPH3L 1.540698897 0.000262408 GOLT1B 1.640960753 1.66048E-05 GORASP1 1.445129847 0.002422195 GPR110 1.378740563 0.009008264 GPR68 1.660968052 9.07733E-06 GPR83 1.405916393 0.005381985 GPRC5C 2.046100648 2.45548E-12 GSPT1 1.30330503 0.032029141 GSR 1.596578429 5.95083E-05 GSTM3 1.545999602 0.000229298 GTF2H2B 1.285900668 0.041521257 GTF3C3 1.418141103 0.004225673 GYG1 1.45467455 0.001974698 H1F0 1.314454078 0.026948234 H2AFY 1.463461941 0.001630536 HADH2 1.370684145 0.010431995 HARS2 1.743635442 6.19838E-07 HAX1 1.434784326 0.003009183 HCFC1 1.46223934 0.001674897 HDAC4 1.362744197 0.012023174 HDAC7A 1.285412533 0.041817254 HDDC3 1.453588718 0.002021519 HDHD1A 1.312575668 0.027753839 HEATR5B 1.312289149 0.027878466 HEBP1 1.381000323 0.008640806 HECTD3 1.430012321 0.003320849 HECW2 1.363474796 0.011868448 HERPUD1 1.464683368 0.001587288 HEY1 1.370239286 0.01051603 HGS 1.575524637 0.000105768 HIBADH 1.688177708 3.88043E-06 HIGD1A 1.329673818 0.021113733 HINT2 1.30598639 0.030740067 HIPK2 1.839303848 1.89442E-08 HIST2H2BF 1.378570778 0.009036417 HIVEP1 1.314692733 0.026847293 HKDC1 1.290225836 0.038972058 HLA-A29.1 1.275426705 0.048256303 HOXD1 1.401641078 0.005848324 HOXD3 1.300341706 0.033505363 HPCAL1 1.712364976 1.7733E-06 HPS5 1.352023818 0.014502733 HS3ST1 1.317285339 0.025770924 HSD17B10 1.32688795 0.022093766 HSPA13 1.457274772 0.001866552 HTATIP2 1.418798121 0.004170347 HTR7 1.363049862 0.011958228 HYAL2 1.289337138 0.039485173 ICA1 1.619137076 3.1444E-05 IDE 1.414513315 0.004543145 IER3 1.390970063 0.007172087 IFNGR2 1.356328445 0.013458662 IFT52 1.275430977 0.048253388 IFT74 1.490992975 0.000875812 IGF2BP2 1.433377981 0.003098176 IGF2BP3 2.010017058 1.34605E-11 IGF2R 1.334710964 0.019435009 IK 1.272952031 0.049968899 IKBKG 1.795617689 9.80264E-08 IL13RA2 1.602809659 5.00066E-05 IL18BP 1.351100181 0.014735627 IL1A 2.270386822 0 IL1R2 1.281727646 0.044107232 IL1RAP 1.43807034 0.002810159 INO80 1.306047506 0.030711193 INSIG1 1.567196273 0.000132077 INTS10 1.283687102 0.042877248 INTS12 1.483066536 0.001050942 INTS5 1.294702622 0.036469217 IRAK2 1.89532311 2.02969E-09 ISG20 1.404670439 0.005514353 ISY1 1.307552291 0.030007328 ITFG1 1.309044441 0.029322634 ITFG3 1.464573023 0.001591152 ITGA2 1.748885632 5.17335E-07 ITGA3 1.376118952 0.009451649 ITGA5 1.864557695 7.04343E-09 ITGAV 1.454796898 0.001969484 ITGB3BP 1.464725561 0.001585813 ITGB4 1.838253164 1.9728E-08 ITIH2 1.274975259 0.048565175 ITPRIP 1.330724052 0.020753944 ITPRIPL2 1.814970203 4.78308E-08 JARID2 2.147117493 1.53211E-14 JMJD8 1.724936266 1.16826E-06 JOSD1 1.537471636 0.000284695 JUP 1.710197424 1.90424E-06 KBTBD8 1.32503265 0.022767516 KCND1 1.335532882 0.019172146 KCNQ2 1.308405482 0.029614224 KCTD10 1.43205754 0.003183882 KCTD2 1.458286528 0.001825948 KDM5B 1.321777396 0.023991499 KIAA0194 1.396535231 0.006451959 KIAA0232 1.311689256 0.028140912 KIAA0494 1.384102944 0.008157735 KIAA0831 1.284975445 0.042083745 KIAA0892 1.314618523 0.026878646 KIAA1211 1.374926232 0.00965961 KIAA1217 1.56589592 0.0001367 KIAA1324 1.413373475 0.0046472 KIAA1539 1.640364968 1.69015E-05 KIAA1598 1.376712947 0.00934955 KIAA1600 1.322502824 0.023714052 KIAA1671 1.326148737 0.022360166 KIF16B 1.407110775 0.005257756 KIF1B 1.780568587 1.6929E-07 KIF21A 1.417462699 0.004283488 KIFAP3 1.370107868 0.010540968 KITLG 1.322464526 0.023728631 KLF10 1.355067975 0.013757447 KLF13 1.90486291 1.36805E-09 KLF4 1.742682326 6.40432E-07 KLF9 1.332392048 0.020193198 KLHDC3 1.321613927 0.024054394 KLHL12 1.47983298 0.001131193 KLHL4 1.486760445 0.000965676 KLHL5 1.54077036 0.000261933 KLK3 1.466086551 0.001538898 KLRC2 1.644004481 1.51645E-05 KLRC3 1.273624319 0.049498917 KRT24 1.491466784 0.000866246 KYNU 3.90220272 0 L3MBTL4 1.427189903 0.003518562 LAMC1 1.283642014 0.042905235 LAMC2 1.538991118 0.000273991 LANCL1 1.496131283 0.00077707 LARP1B 1.275897949 0.047935564 LARS 1.40615017 0.005357466 LCMT1 1.369367538 0.010682418 LDLR 1.794529981 1.0201E-07 LEMD3 1.329797449 0.021071107 LGTN 1.279094871 0.045804488 LHFPL2 1.302578259 0.032386128 LIMS1 1.278847302 0.04596675 LMBRD1 1.459178576 0.001790817 LMNA 1.456124268 0.001913721 LMO4 1.4839636 0.001029623 LOC100127888 1.308300133 0.02966253 LOC100128405 1.276993534 0.047196479 LOC100128977 1.299762148 0.033800529 LOC100129086 1.384789741 0.008054067 LOC100129361 1.293291355 0.037243613 LOC100129860 1.284264232 0.042520305 LOC100129908 1.337907441 0.01842964 LOC100130154 1.301721394 0.032811227 LOC100130886 2.449927887 0 LOC100131261 1.279025732 0.045849757 LOC100131403 1.321658898 0.024037078 LOC100131785 1.46745026 0.001493161 LOC100131905 1.274594686 0.048826783 LOC100132510 1.280289315 0.045028077 LOC100132707 1.405858472 0.005388075 LOC100132787 1.274764625 0.048709827 LOC100133163 1.299893563 0.033733413 LOC100133169 1.310120637 0.028836901 LOC100133171 1.457825398 0.001844354 LOC100133576 1.369676855 0.010623119 LOC100133741 1.28988355 0.03916904 LOC100134265 1.794248806 1.03065E-07 LOC100134537 1.536302593 0.000293194 LOC146517 1.368705119 0.010810381 LOC151300 1.333036392 0.019980049 LOC162073 1.483303701 0.001045267 LOC201175 1.389826555 0.007328545 LOC23117 1.305475151 0.030982477 LOC255326 1.450273396 0.002170778 LOC284293 1.419803509 0.00408694 LOC286208 1.290901879 0.038585372 LOC339352 1.30343476 0.031965762 LOC339843 1.36431397 0.011692863 LOC344887 2.092146602 2.56906E-13 LOC345645 1.309762548 0.028997774 LOC388789 1.311279778 0.028321233 LOC389137 1.420129222 0.004060241 LOC390345 1.349361813 0.015182686 LOC400406 1.487675483 0.000945559 LOC401233 1.35066587 0.014846245 LOC402175 1.423902505 0.003762126 LOC402251 1.281016366 0.04456069 LOC440055 1.317960167 0.025496757 LOC441268 1.3808854 0.008659171 LOC442057 1.33472943 0.01942907 LOC552889 1.44862717 0.002248545 LOC613037 1.317194354 0.025808077 LOC641825 1.323657821 0.023277882 LOC642031 2.020057542 8.43392E-12 LOC642197 1.402462922 0.005755991 LOC642570 1.276510443 0.04752124 LOC643479 1.32355732 0.023315564 LOC643668 1.392552599 0.006960422 LOC643847 1.332544865 0.020142472 LOC643938 1.330090945 0.020970207 LOC644086 1.409679784 0.004999158 LOC644124 1.346005749 0.016078802 LOC644132 1.663977303 8.27642E-06 LOC644173 1.309317391 0.029198801 LOC644330 1.278732171 0.046042367 LOC644496 1.553749395 0.000187845 LOC644607 1.303124469 0.032117527 LOC644739 1.43823284 0.002800632 LOC644761 1.430384138 0.003295561 LOC644869 1.35860354 0.012933535 LOC644979 1.318801942 0.025158191 LOC645233 1.373631592 0.009889856 LOC645381 1.55863714 0.000165422 LOC645387 1.343148522 0.016877078 LOC645715 1.334852591 0.019389497 LOC645931 1.285037111 0.042046065 LOC646144 1.280940087 0.044609542 LOC646754 1.311702731 0.028134995 LOC647349 1.608175965 4.299E-05 LOC648024 1.289713169 0.039267394 LOC648665 1.313336265 0.027425251 LOC648980 1.514626813 0.000500435 LOC650737 1.311762009 0.028108975 LOC650832 1.288074011 0.040223919 LOC651476 1.293025821 0.037390809 LOC651697 1.453252425 0.002036223 LOC651834 1.298810376 0.0342899 LOC652045 1.283839135 0.042782985 LOC652881 1.377803182 0.009164662 LOC653103 1.4073217 0.005236084 LOC653105 1.282541274 0.043593093 LOC653219 1.297438463 0.035005527 LOC653450 1.346803224 0.015861858 LOC653506 1.411341885 0.004837945 LOC653620 1.282788808 0.043437637 LOC727865 1.294685164 0.036478715 LOC727938 1.496946391 0.000762383 LOC728411 1.367012312 0.011143467 LOC728457 1.33464473 0.019456325 LOC728492 1.317488522 0.025688117 LOC728661 1.60997211 4.08571E-05 LOC728855 1.33134361 0.020544141 LOC728877 1.371758527 0.01023145 LOC728931 1.318026136 0.025470087 LOC729009 1.875930611 4.46885E-09 LOC729148 1.570929293 0.000119605 LOC729574 1.301474738 0.032934445 LOC729660 1.436226401 0.002920327 LOC729776 1.328416373 0.021551436 LOC729779 1.927775758 5.21564E-10 LOC729843 1.335354327 0.019228992 LOC729960 1.313094962 0.027529144 LOC729978 1.318296102 0.025361187 LOC730235 1.351658061 0.014594576 LOC730278 1.435917834 0.002939139 LOC730284 1.304016253 0.031682943 LOC731511 1.326565095 0.022209786 LOC732138 1.278959722 0.045893011 LOC732360 1.340825328 0.017550906 LOC88523 1.404193754 0.005565755 LOC93432 1.293690461 0.037023264 LPCAT3 1.28753472 0.040542727 LRBA 1.377729051 0.009177132 LRP5 1.651438804 1.21294E-05 LSM2 1.305774139 0.030840516 LTA4H 1.280883292 0.044645944 LY96 1.273481988 0.049598122 LYPD3 1.286338178 0.041257403 LYPLA2 1.293045273 0.03738001 LYPLA2P1 1.325387681 0.022637264 M160 1.640507857 1.68298E-05 MAF1 1.30791211 0.029841018 MAFG 1.496450116 0.000771294 MALL 2.285518606 0 MAP2K3 1.33347654 0.019835548 MAP3K2 1.294639269 0.036503695 MAP4K4 1.776025406 1.9925E-07 MAP7D1 1.293902514 0.036906621 MAPK6 1.566703009 0.000133813 MAPKAP1 1.378507911 0.009046861 MAPKAPK5 1.329513935 0.021168966 MARCKSL1 1.373708924 0.009875969 MARS 1.422381326 0.003879864 MBD6 1.294166231 0.036761981 MBNL2 1.510739411 0.000549605 MBOAT1 1.369102283 0.0107335 MBP 1.723916758 1.20879E-06 MCTP1 1.469073399 0.001440342 MDC1 1.695550265 3.06488E-06 MDP1 1.352200268 0.014458604 ME1 1.354574539 0.013875961 MED20 1.685290558 4.25324E-06 MED8 1.378008931 0.009130132 MEF2D 1.835289887 2.21118E-08 MEGF9 1.595195072 6.18372E-05 METRNL 1.360751347 0.012454141 MFF 1.346903035 0.015834883 MFSD1 1.284496421 0.042377381 MGAT4B 1.303101165 0.032128949 MGC42630 1.315578235 0.026475514 MGC4294 1.34628299 0.016003095 MGC71993 1.296809834 0.035337509 MGC87042 1.517055287 0.000471819 MGST1 1.745386503 5.83652E-07 MID1IP1 1.489199685 0.000912904 MIDN 1.474243605 0.001283262 MIF4GD 1.411648332 0.004808733 MIR1281 1.338506189 0.01824633 MIR1976 1.336014355 0.019019571 MIR302C 1.320027344 0.024672068 MKLN1 1.409336501 0.005033044 MLKL 1.305460755 0.030989326 MMP1 1.375008173 0.009645196 MOBKL2C 1.287267868 0.040701237 MPDZ 1.477247357 0.00119936 MPHOSPH8 1.301517442 0.032913085 MR1 1.685447516 4.23212E-06 MRPS10 1.299467075 0.033951628 MRPS31 1.334229038 0.019590557 MRPS33 1.582055562 8.86705E-05 MRRF 1.290225718 0.038972126 MSRB2 1.552757877 0.000192727 MTDH 1.372661531 0.010065504 MTHFD2L 1.369821389 0.010595509 MTMR11 1.358293625 0.013004009 MTMR14 1.706345827 2.16011E-06 MTMR2 1.442479482 0.002561776 MTMR9 1.805426069 6.82828E-08 MTX2 1.322839863 0.023586069 MURC 1.279656901 0.045437828 MUT 1.301025916 0.033159634 MVP 1.345164658 0.016310362 MXD1 1.607654834 4.36283E-05 MXD4 1.35870456 0.012910634 MYADM 1.392103756 0.007019887 MYLIP 1.567165773 0.000132183 MYPOP 1.296156962 0.035685022 N4BP1 1.328427663 0.021547472 N4BP2L2 1.284148934 0.042591422 NAMPT 1.617338861 3.31115E-05 NAT15 1.273437658 0.049629053 NAV3 1.484347606 0.001020619 NBEA 1.550310398 0.000205291 NBL1 1.858593385 8.92057E-09 NCOA1 1.279440669 0.045578614 NCOA3 1.516952402 0.000473 NCOA7 1.507216811 0.000597982 NCOR2 1.742687227 6.40324E-07 NDNL2 1.291486269 0.038253635 NDRG1 1.504759888 0.00063402 NDUFA9 1.35625647 0.013475571 NDUFV1 1.28149168 0.044257252 NECAP1 1.452964183 0.002048903 NEK3 1.358939194 0.01285758 NENF 1.334359954 0.019548197 NFE2L2 1.342996724 0.01692042 NFKBIA 1.448084533 0.002274727 NGLY1 1.321775171 0.023992354 NGRN 1.286129846 0.041382874 NINJ1 1.685711631 4.19681E-06 NIPA1 1.421866244 0.003920473 NKAP 1.355042019 0.013763659 NKIRAS1 1.363684126 0.011824436 NKIRAS2 1.86570916 6.72813E-09 NLRX1 1.449012367 0.002230126 NME6 1.31009609 0.028847905 NMI 1.326923721 0.022080943 NOP2 1.422733187 0.003852341 NP 1.612150362 3.84046E-05 NPAS2 1.462751736 0.001656173 NPL 1.335956227 0.019037936 NR1D2 1.292222408 0.037839069 NR1H2 1.402661182 0.005733911 NRG1 1.412210726 0.004755532 NRP1 1.307184592 0.030178072 NSMAF 1.518448262 0.000456096 NSMCE2 1.279053204 0.045831764 NTN4 1.356534722 0.013410303 NUDT5 1.288570859 0.039932007 NUPR1 1.601284517 5.219E-05 OCIAD2 1.513667654 0.000512173 ODZ3 1.424108841 0.003746405 OGFR 1.390363592 0.007254695 OKL38 2.305738081 0 OMA1 1.543822447 0.000242395 OPTN 1.411723424 0.004801599 OR2A42 1.296237411 0.035642049 OR7E156P 1.32567215 0.022533353 OSBPL2 1.277922761 0.046576804 OSGIN1 1.676287047 5.64841E-06 OSTC 1.274537977 0.048865861 OSTF1 1.305879837 0.03079046 P2RY11 1.278591453 0.046134925 P8 1.580435317 9.26515E-05 PAAF1 1.400107603 0.006024127 PACSIN2 1.531743137 0.000328651 PAG1 1.378825084 0.008994277 PAIP1 1.277614122 0.046781898 PAN3 1.294060681 0.036819816 PANX2 1.588254784 7.48754E-05 PAPD4 1.293648783 0.037046224 PARN 1.375034589 0.009640553 PARP6 1.343298207 0.016834432 PAXIP1 1.324657623 0.02290579 PBX2 1.328189507 0.021631217 PCBP3 1.276374398 0.047613019 PCDH20 1.368202808 0.010908302 PCDHB17 1.313424541 0.027387326 PCGF2 1.35096843 0.014769108 PCK2 1.584911835 8.20414E-05 PCMTD1 1.597523383 5.79653E-05 PDCD10 1.418378729 0.004205588 PDXK 1.461078628 0.001718027 PELI2 1.623550754 2.76817E-05 PERP 1.568819816 0.00012651 PET112L 1.342648257 0.017020277 PEX1 1.289219826 0.039553315 PEX16 1.351775669 0.01456499 PEX19 1.306052178 0.030708986 PEX6 1.429129052 0.003381621 PFKFB3 1.489935961 0.000897504 PGD 2.065055804 9.80993E-13 PHACTR2 1.281179634 0.044456272 PHC2 1.67959473 5.09149E-06 PHF16 1.504554336 0.000637125 PHF17 1.380801986 0.008672522 PHF3 1.298897946 0.034244632 PHGDH 1.348910893 0.015300536 PHLDA2 1.274857984 0.048645671 PHYH 1.448431087 0.002257974 PI15 1.286704643 0.041037442 PICALM 1.371261105 0.010323877 PIGK 1.32716071 0.021996147 PIGP 1.690405585 3.61432E-06 PIGQ 1.364182319 0.011720259 PIP4K2A 1.546482567 0.000226483 PIPSL 1.453780213 0.002013189 PIR 1.996279477 2.53296E-11 PITRM1 1.319954286 0.024700828 PKIG 1.385158395 0.0079989 PKN1 1.376825596 0.009330296 PLD3 1.35881681 0.012885229 PLEK2 1.80755174 6.31004E-08 PLEKHA9 1.433922339 0.003063452 PLEKHF1 1.343258633 0.016845698 PLEKHH1 1.370506187 0.010465541 PLS1 1.276406821 0.047591133 PLXNA1 1.34220418 0.017148262 PMP22 1.300118866 0.033618602 PMPCB 1.431059562 0.003250068 PNPLA8 1.28730094 0.040681565 PNPO 1.31397682 0.027151046 PNRC2 1.357931625 0.013086748 POFUT1 1.344388065 0.016526695 POFUT2 1.279001098 0.045865894 POLDIP2 1.27460241 0.048821462 POLR2E 1.424085912 0.003748149 POLR3GL 1.328067852 0.021674101 POPDC3 1.352317812 0.014429271 POT1 1.284198186 0.042561031 PPCS 1.278482486 0.046206701 PPFIBP1 1.347552747 0.015660252 PPIC 1.283596175 0.042933704 PPIL1 1.364058491 0.011746078 PPP1R11 1.278002199 0.046524133 PPP2R2C 1.354343758 0.013931692 PPP6C 1.617494776 3.29637E-05 PRAGMIN 1.406361504 0.005335386 PRDM4 1.52468177 0.00039151 PRDX1 1.48811477 0.00093604 PRKAB2 1.355582734 0.013634743 PRKCA 1.358418904 0.012975481 PRKCD 1.44267669 0.002551145 PRMT2 1.401808595 0.005829398 PRR14 1.359202736 0.012798214 PRSS23 1.423623336 0.003783491 PRSS3 1.807612658 6.29576E-08 PSAP 1.423762646 0.003772816 PSAT1 1.539343822 0.00027156 PSEN2 1.307453339 0.030053198 PSKH2 1.332054394 0.020305661 PSMA1 1.435250417 0.002980201 PSMA3 1.323524497 0.023327882 PSMB7 1.326745862 0.022144763 PSMC2 1.283534102 0.04297228 PSMD10 1.289896004 0.039161859 PSMF1 1.299873957 0.033743419 PTGR1 1.94974447 2.02339E-10 PTGS2 1.586916522 7.76704E-05 PTHLH 1.634330637 2.02044E-05 PTPDC1 1.421588416 0.003942534 PTPRK 2.077798415 5.2458E-13 PUS3 1.304199765 0.03159412 PVRL3 1.535065793 0.000302443 PXMP3 1.365738641 0.011399932 PYGB 1.334956106 0.01935629 QARS 1.364858436 0.011580151 RAB10 1.373236151 0.009961132 RAB22A 1.644828626 1.47955E-05 RAB2A 1.305849433 0.030804852 RAB2B 1.464316369 0.001600172 RAB31 1.750488395 4.89439E-07 RAB40A 1.313036413 0.027554402 RAB8B 1.341018621 0.01749398 RAB9A 1.29035307 0.038899042 RAC2 1.402773661 0.005721418 RAD1 1.289542657 0.039366025 RALGAPA1 1.887371564 2.81104E-09 RALGDS 1.278404234 0.0462583 RAP1GAP 3.2937347 0 RAPGEF2 1.406884539 0.005281089 RASA1 1.377261468 0.009256125 RBBP4 1.328883274 0.021388026 RBM22 1.382870695 0.008346677 RBM34 1.324211325 0.023071263 RBM47 1.797944773 9.00029E-08 RCBTB2 1.44293509 0.002537275 RCOR3 1.276461045 0.047554549 RDH10 1.297465314 0.034991404 RECQL 1.333963314 0.019676773 RECQL5 1.349367021 0.01518133 RELB 1.380977981 0.008644373 REPIN1 1.46549788 0.001559033 REXO1 1.689652474 3.70226E-06 REXO1L5P 1.311400827 0.028267827 RFNG 1.341690646 0.017297289 RGS17 1.743143649 6.30383E-07 RGS20 1.356513847 0.01341519 RICS 1.417997852 0.004237823 RIOK3 1.51299876 0.000520509 RNASEH1 1.36301072 0.011966528 RNF11 1.418876307 0.004163807 RNF113A 1.370222031 0.010519302 RNF121 1.418929809 0.004159336 RNF13 1.371103069 0.010353394 RNF14 1.518797848 0.000452228 RNF141 1.308294271 0.02966522 RNF149 1.373151141 0.009976513 RNF160 1.505372336 0.000624854 RNF170 1.31884473 0.025141082 RNF181 1.443094637 0.002528746 RNF19B 1.326991457 0.022056678 RNF216 1.350406879 0.014912549 RNF38 1.630588332 2.25513E-05 RNF41 1.337238517 0.018636287 RNF44 1.770559734 2.42104E-07 RNF7 1.370106328 0.010541261 RPGR 1.300961128 0.033192244 RPH3AL 1.310901102 0.028488845 RPIA 1.320434159 0.024512436 RPL13 1.280173157 0.045103114 RPL34 1.47817287 0.001174539 RPLP0 1.351966998 0.014516968 RPRC1 1.460386234 0.001744235 RPS4X 1.321800882 0.023982474 RPS6KA2 1.513135529 0.000518795 RRAGC 1.282321059 0.043731769 RRAS2 1.289770204 0.039234448 RSU1 1.316403984 0.02613271 RUFY3 1.2768926 0.047264185 RXRA 1.542336948 0.000251728 S100A10 1.380553122 0.008712463 S100A11 1.34385244 0.016677329 S100A16 1.336683221 0.018809327 S100A4 1.325965172 0.022426738 S100A7A 1.297926065 0.03474979 SAMD11 1.32770841 0.021801227 SASH1 1.359143592 0.012811517 SBF1 1.482147699 0.001073198 SCAND1 1.62628886 2.55664E-05 SCD 1.657515615 1.00871E-05 SCG5 1.506491643 0.000608417 SCYL2 1.519004756 0.000449952 SDCBP 1.514503163 0.000501934 SDCCAG1 1.305675837 0.030887131 SDSL 1.372160696 0.01015725 SEC11C 1.377351959 0.009240791 SEC24C 1.302835989 0.032259158 SEL1L3 1.961633641 1.20107E-10 SEMA4B 1.507556942 0.000593145 SEPT9 1.453905637 0.00200775 SERF1B 1.302491824 0.032428802 SERPINA1 1.412683938 0.004711174 SERPINB2 2.786943708 0 SERPINB5 1.610325595 4.04493E-05 SERPINE2 1.506249188 0.000611943 SERPINI1 1.343690497 0.016723103 SETDB2 1.30511295 0.031155175 SF3B5 1.349245141 0.015213104 SFRS2B 1.353771426 0.014070736 SFRS4 1.300558925 0.033395283 SFXN5 1.41121126 0.004850445 SGPP2 1.274005129 0.04923427 SH3GL1 1.285481498 0.041775331 SH3KBP1 2.291463549 0 SHMT2 1.275788828 0.048009682 SIDT2 1.510763025 0.000549293 SIGLEC9 1.304686756 0.031359404 SIP1 1.303213095 0.032074119 SIPA1L2 1.485291713 0.000998787 SIRT5 1.407128856 0.005255895 SIRT7 1.287643191 0.040478439 SKP2 1.331129061 0.02061659 SLC10A7 1.356912489 0.013322129 SLC15A4 1.352848571 0.014297458 SLC23A2 1.383580504 0.008237378 SLC23A3 1.622250546 2.87432E-05 SLC25A14 1.307188421 0.03017629 SLC25A39 1.405571379 0.005418353 SLC2A1 1.3624623 0.012083339 SLC2A3 1.928313187 5.09754E-10 SLC30A5 1.282373866 0.043698483 SLC35A2 1.341507919 0.017350582 SLC35A5 1.339442251 0.017962864 SLC35C2 1.318867443 0.025132004 SLC35D2 1.456798149 0.001885963 SLC38A1 1.311801987 0.028091438 SLC38A2 1.33619461 0.018962716 SLC38A6 1.288567432 0.039934014 SLC38A9 1.391246887 0.007134656 SLC39A11 1.489054182 0.000915976 SLC3A2 1.534812627 0.000304369 SLC6A9 1.919889505 7.28811E-10 SLC7A11 1.517062664 0.000471734 SLC7A5 1.400260591 0.00600638 SLCO4A1 1.31918566 0.025005112 SLK 1.395881491 0.006533099 SLMAP 1.418333179 0.004209432 SLU7 1.454984414 0.001961518 SMAD1 1.384283208 0.008130413 SMAD3 1.351658038 0.014594582 SMAGP 1.348699151 0.015356146 SMAP2 1.454031461 0.002002307 SMARCAD1 1.340860643 0.017540494 SMARCD1 1.431125069 0.003245686 SMUG1 1.288135579 0.040187652 SNAP23 1.446232825 0.002366162 SNAP91 1.423875494 0.003764189 SNHG5 1.310884108 0.028496386 SNORA11D 1.277092656 0.047130064 SNORD13 1.553589806 0.000188623 SNX1 1.419648257 0.004099721 SNX13 1.301579653 0.032881988 SON 1.285715401 0.0416334 SOX4 1.215173814 0.105312676 SPANXA1 1.674477749 5.97718E-06 SPANXA2 1.362403553 0.012095911 SPANXB1 1.42273162 0.003852463 SPANXB2 1.455125493 0.001955544 SPANXC 1.347943166 0.015556111 SPANXD 1.732613217 9.02303E-07 SPANXE 1.607344176 4.4013E-05 SPATA2L 1.332718337 0.020085022 SPATS2 1.286858081 0.040945628 SPATS2L 1.291834871 0.038056856 SPG11 1.326167029 0.022353541 SPINK1 1.389469903 0.007377955 SPINK6 1.311897803 0.028049443 SPP1 1.284485309 0.042384212 SPRED2 1.316663662 0.026025676 SPRY2 1.611530169 3.90883E-05 SPRY4 1.41956599 0.004106509 SPRYD3 2.14869667 1.40998E-14 SPTLC3 1.322089433 0.023871825 SQRDL 1.28454136 0.042349764 SQSTM1 1.51109437 0.000544936 SREBF1 1.478694727 0.001160752 SRF 1.292092637 0.037911884 SRGAP1 1.35437459 0.013924235 SRI 1.304376721 0.031508665 SRPR 1.39394836 0.006778335 SRXN1 2.300652417 0 SSR1 1.339726037 0.01787767 SSR3 1.364369994 0.011681221 ST13 1.409738577 0.004993375 ST7 1.486753349 0.000965833 ST8SIA4 1.28711927 0.040789721 STAMBP 1.290629563 0.038740755 STEAP1 1.441124273 0.002635921 STK24 1.397852416 0.00629118 STK36 1.352313807 0.014430269 STK40 2.384344168 0 STX11 1.292408539 0.03773483 STX1A 1.37648275 0.009389003 STX3 2.156439594 9.32587E-15 STX6 1.348834674 0.015320534 STXBP5 1.380327887 0.008748751 STYXL1 1.702403316 2.45598E-06 SUV420H1 1.343893813 0.016665652 SV2B 1.282061172 0.043895885 SVIL 1.319172554 0.025010327 SYNJ2 1.291885859 0.038028144 SYT1 1.437842701 0.002823553 SYT15 1.48686921 0.000963264 SYVN1 1.558046786 0.000167991 TAF4 1.340674555 0.017595419 TALDO1 1.546831996 0.000224467 TATDN3 1.287287506 0.040689554 TAX1BP1 1.570034107 0.00012249 TBC1D13 1.598130273 5.69944E-05 TBC1D19 1.350783149 0.014816304 TBCE 1.280037718 0.045190733 TBK1 1.384777484 0.008055907 TCEB2 1.282270126 0.043763894 TCN1 1.621334227 2.95144E-05 TCTN1 1.282042324 0.043907807 TDG 1.363468902 0.011869689 TEAD3 1.42112664 0.003979449 TEF 1.346541245 0.015932848 TERF2IP 1.27483499 0.048661466 TEX264 1.341219844 0.017434886 TFPI 1.930897357 4.56514E-10 TGFBR2 1.493446087 0.000827314 TGFBR3 1.638271532 1.79845E-05 THADA 1.296727335 0.035381268 THEM2 2.339674002 0 THNSL1 1.317574248 0.025653246 TJAP1 1.305041383 0.031189392 TJP1 1.305396527 0.031019898 TKT 1.671061686 6.64834E-06 TLK1 1.331044227 0.020645297 TM2D3 1.43124818 0.003237465 TM4SF1 1.813233121 5.1048E-08 TM4SF18 1.306230616 0.030624819 TM4SF19 2.113510581 8.72635E-14 TMBIM4 1.537092887 0.000287423 TMEM106B 1.464909049 0.001579413 TMEM126A 1.27429717 0.04903208 TMEM126B 1.307159633 0.030189691 TMEM127 1.327712052 0.021799936 TMEM131 1.371639179 0.01025356 TMEM135 1.514159154 0.000506126 TMEM144 1.674601965 5.95404E-06 TMEM14C 1.381243366 0.008602079 TMEM150A 1.303979024 0.031700988 TMEM154 1.290855964 0.038611536 TMEM156 1.465831231 0.001547601 TMEM158 1.733141781 8.86311E-07 TMEM165 1.305339355 0.031047131 TMEM180 1.292416313 0.037730482 TMEM185B 1.305066044 0.031177598 TMEM189 1.458996557 0.001797935 TMEM189-UBE2V1 1.406851913 0.005284462 TMEM2 1.747591622 5.40967E-07 TMEM206 1.291700466 0.038132627 TMEM42 1.473919255 0.001292636 TMEM43 1.535660663 0.000297961 TMEM44 1.367050357 0.011135884 TMEM55A 1.390660556 0.007214141 TMEM63A 1.309038367 0.029325394 TMEM77 1.400819898 0.005941892 TMEM86B 1.40552458 0.005423303 TMSB4X 1.307822051 0.029882572 TMSL3 1.627363423 2.47789E-05 TMX1 1.365000009 0.011550998 TNFAIP1 1.350730687 0.014829691 TNFRSF10B 1.531483907 0.000330782 TNFRSF14 1.289333377 0.039487357 TNFRSF21 2.175752599 3.33067E-15 TNIP1 1.681629323 4.77541E-06 TNIP3 1.38505292 0.00801465 TNKS1BP1 1.47561577 0.00124429 TOM1 1.300318736 0.033517021 TOR1AIP1 1.33427498 0.019575683 TOX2 1.753279383 4.44283E-07 TP53I3 1.646242947 1.4182E-05 TPBG 1.468332307 0.001464243 TPK1 1.806952447 6.45216E-08 TPP1 1.580313227 9.29582E-05 TPPP3 1.356003868 0.01353506 TPRG1L 1.36941522 0.010673258 TRAF3IP2 1.649949034 1.2687E-05 TRAFD1 1.291029986 0.038512451 TRIB1 1.622968483 2.81524E-05 TRIB3 1.531548044 0.000330253 TRIM38 1.350212783 0.014962405 TRIM5 1.343578298 0.01675488 TRIM68 1.491493351 0.000865712 TRIML2 2.709516436 0 TRMT112 1.31603283 0.02628633 TRO 1.305484116 0.030978212 TROVE2 1.29830736 0.034550878 TSC22D1 2.507089333 0 TSC22D3 1.375931262 0.009484113 TSG101 1.419553968 0.004107501 TSGA14 1.547562802 0.000220305 TSKU 1.792599532 1.09468E-07 TSNAX 1.312855072 0.027632754 TSPAN8 1.299610375 0.033878178 TUBB3 1.316506476 0.026090421 TUBB4 1.297897924 0.034764507 TUBE1 1.566505532 0.000134514 TUG1 1.422103274 0.003901738 TUSC4 1.324849325 0.02283502 TXN 1.301048301 0.033148372 TXNRD1 1.536839904 0.000289259 UBA52 1.327297895 0.021947187 UBAP2L 1.390279548 0.007266209 UBC 1.301777812 0.032783097 UBE1DC1 1.289607496 0.039328496 UBE2D2 1.300091399 0.033632582 UBE2J2 1.293211868 0.037287626 UBE2O 1.352833033 0.014301302 UBE3B 1.459625329 0.001773454 UBN1 1.393352846 0.006855503 UBN2 1.280374561 0.044973073 UBQLN2 1.308204065 0.029706638 UBQLN3 1.807628907 6.29196E-08 UBXN11 1.327478227 0.021882968 UBXN6 1.318736608 0.025184332 UCN 1.338927959 0.018118138 UGDH 1.952810395 1.76984E-10 UGT2B11 1.293383056 0.03719289 UHRF1BP1 1.370977312 0.010376935 ULK1 1.618978904 3.15874E-05 UNC50 1.311242725 0.028337597 UNC84B 1.534322 0.000308135 UQCC 1.616259784 3.4152E-05 UROS 1.338013859 0.018396945 USF2 1.624895526 2.66229E-05 USO1 1.54044909 0.000264073 USP36 1.333529856 0.019818105 USP42 1.400249053 0.006007716 USP48 1.314642526 0.026868502 USP8 1.288852068 0.039767553 UTP14C 1.328559783 0.021501132 UTP3 1.294186553 0.036750854 VAMP4 1.575029951 0.000107182 VAMP7 1.324511059 0.02296002 VAMP8 1.390117928 0.007288395 VCL 1.398039883 0.006268587 VCP 1.299617385 0.033874589 VPS33B 1.400859225 0.005937381 VPS35 1.585801754 8.00732E-05 VPS36 1.645608675 1.44541E-05 VPS37C 1.438248754 0.0027997 VPS41 1.478777758 0.001158572 VRK3 1.407672156 0.005200252 WASF2 1.660669317 9.16075E-06 WBP1 1.324323179 0.023029697 WBP2 1.602074064 5.10487E-05 WBSCR27 1.315018309 0.026710096 WDR22 1.307138782 0.030199401 WDR37 1.287064279 0.040822506 WDR41 1.398066719 0.006265359 WDR51B 1.330664868 0.02077408 WDR55 1.287888474 0.040333371 WDR59 1.275301256 0.048341975 WDR78 1.285300295 0.041885554 WDSUB1 1.27908199 0.045812919 WFDC3 1.567262792 0.000131844 WNK4 1.35835201 0.012990707 WRB 1.428145524 0.003450467 WRN 1.403218534 0.005672243 WWP1 1.809194477 5.93581E-08 XAGE1 1.288424254 0.040017961 XBP1 1.816835205 4.45953E-08 XKR8 1.27651854 0.047515782 XPNPEP1 1.373829627 0.009854329 YARS 1.453830087 0.002011025 YIPF5 1.293293099 0.037242648 YPEL5 1.403062013 0.005689501 YRDC 1.321693993 0.024023571 YWHAG 1.352942314 0.014274285 ZBTB43 1.386388662 0.007817195 ZBTB45 1.387395761 0.007671163 ZC3H12A 1.382943763 0.008335367 ZCCHC24 1.314488059 0.026933842 ZCCHC6 1.282006248 0.043930633 ZDHHC11 1.332238568 0.020244252 ZDHHC4 1.490105183 0.000893998 ZDHHC9 1.367898057 0.010968086 ZEB1 1.303516124 0.031926064 ZER1 1.300509941 0.033420081 ZFAND2A 1.318073735 0.025450858 ZFAND5 1.279114762 0.045791471 ZFYVE16 1.346715479 0.015885604 ZFYVE26 2.079132542 4.91052E-13 ZMAT2 1.316865995 0.025942533 ZMIZ2 1.727792718 1.06153E-06 ZMYM4 1.374881949 0.009667407 ZMYM6 1.276850623 0.047292366 ZNF187 1.414279963 0.004564276 ZNF25 1.427874094 0.003469687 ZNF252 1.444889843 0.002434545 ZNF263 1.273605181 0.049512247 ZNF32 1.299298037 0.034038438 ZNF333 1.30290624 0.032224621 ZNF358 1.579554319 9.48861E-05 ZNF362 1.525573764 0.000382995 ZNF395 1.290236887 0.038965712 ZNF398 1.303682623 0.031844956 ZNF419 1.332272411 0.020232985 ZNF426 1.354872256 0.01380435 ZNF524 1.390381908 0.007252188 ZNF585A 1.389953697 0.007311002 ZNF643 1.350656369 0.014848673 ZNF746 1.318364422 0.02533369 ZNF768 1.362557817 0.012062924 ZNF783 1.341892792 0.017238495 ZNF790 1.41333889 0.00465039 ZNF827 1.30299077 0.032183104 ZNF845 1.313741869 0.027251356 ZNHIT1 1.361359555 0.012321215 ZNHIT3 1.331801086 0.02039038 ZSCAN18 1.344110911 0.016604493 ZSWIM1 1.378645999 0.009023934 ZSWIM4 1.92577698 5.67874E-10 ZSWIM7 1.348472883 0.015415764 ZXDB 1.280279135 0.045034649 ZZEF1 1.506440997 0.000609152

Supplementary Table S4. List of 26 genes that were obtained by overlapping the 100 genes that were enriched in highly metastatic derivatives with the 1356 genes whose expressions were downregulated upon SOX4 knockdown.

MDA-LM2 / MDA-parental CN34-LM1A / CN34-parental MDA-LM2 siControl (avg) / siSOX4 (avg)

SYMBOL fold_change p_value fold_change p_value fold_change p-value AKAP13 1.751326414 0.00025 1.345031537 5.47401E-07 1.35821188 0.013022653 ALDH3A2 1.844933736 0.00005 2.301891766 0 2.208918015 5.55112E-16 CADM1 5.448427855 0.00005 452.8313404 8.86749E-10 2.095662304 2.15383E-13 DUSP4 1.621568535 0.0011 1.290674314 2.62376E-07 1.311260891 0.028329574 EREG 5.149991317 0.00005 2.566869587 0 2.353098332 0 FLRT2 2.125555604 0.0001 3.1272618 0 1.301047971 0.033148538 FSCN1 3.016509237 0.00005 3.260131143 0 1.426707244 0.003553412 FZD8 3.241900921 0.00005 5.716808642 2.774E-11 1.433526148 0.00308869 IGF2BP3 1.643170288 0.00125 1.675326168 0 2.010017058 1.34605E-11 ITGB4 3.716719983 0.00005 4.939208942 0 1.838253164 1.9728E-08 KLF9 2.370662027 0.0005 1.388369907 1.76317E-08 1.332392048 0.020193198 LOC100127888 17.68960588 0.00005 4.822930431 0 1.308300133 0.02966253 MMP1 2.425496336 0.00005 151.9339006 0 1.375008173 0.009645196 ODZ3 1.948763477 0.00005 6.035402553 0 1.424108841 0.003746405 PCDH20 7.769436678 0.0013 8.567949638 0 1.368202808 0.010908302 PHGDH 6.93713519 0.00005 3.162794892 0 1.348910893 0.015300536 PHLDA2 2.194770363 0.00005 1.503132305 6.42647E-08 1.274857984 0.048645671 PPP2R2C 2.892486047 0.00005 1.800383191 4.57406E-08 1.354343758 0.013931692 SASH1 1.738197481 0.0007 1.46433841 6.93088E-11 1.359143592 0.012811517 SEL1L3 3.644775615 0.00005 2.66983392 0 1.961633641 1.20107E-10 SEMA4B 2.158785646 0.00005 1.377938978 9.84579E-05 1.507556942 0.000593145 SERPINB5 7.136021688 0.0004 51.50747811 0.000131962 1.610325595 4.04493E-05 SERPINE2 2.38073988 0.00005 3.008720309 0 1.506249188 0.000611943 SLCO4A1 4.173390736 0.00005 1.515275373 0.00347006 1.31918566 0.025005112 SOX4 1.92576545 0.0008 3.969700045 0 1.215173814 0.105312676 ST8SIA4 2.94857931 0.0001 1.687207017 0.000294438 1.28711927 0.040789721 TMEM154 2.097048168 0.0004 1.63610008 2.34479E-12 1.290855964 0.038611536 TMEM2 1.686470403 0.0004 1.793044135 0 1.747591622 5.40967E-07