Version 3 as of 9/3/2019

HudsonAlpha Institute for Biotechnology A and M University Tuskegee University University of Alabama at Birmingham University of Alabama in Huntsville University of Southern Research

Mon: Table&of&Contents& & ! Executive&Summary…………………………………………………………………………………….! 1! ! I.!Introduction………………………………………………………………………………………………! 2! ! II.!Research!Expertise!and!Capabilities…………………………………………………………..! 3! ! III.!Strategies!for!Enhancing!Collaboration……………………………………………………..! 4! ! IV.!Growth!of!Alabama!R&D…………………………………………………………………………..! 5! ! ! ! Statewide!Priorities………………………………………………………………………! 6! ! Institutional!Investment!Priorities…………………………………………………! 7! ! V.!Institutional!Points!of!Contact……………………………………………………………………! 9! ! VI.!Research!Expertise!and!Capabilities!Maps…………………………………………………! 10! ! ! Advanced!Manufacturing…………………………………………………………….....! 11! ! Agricultural!Products/Food!Production………………………………...... ! 12! ! Biosciences/Biotechnology………………………………………………...... ! 13! ! Chemical/Petrochemical………………………………………………………………..! 14! ! Energy…………………………………………………………………………………………..! 15! ! Forestry!Products……………………………………………………………...... !………..! 16! ! Information!Technology!and!Cybersecurity…………………………………....! 17! ! Metal!and!Advanced!Materials…………………………………………...... !! 18! ! Nanotechnology…………………………………………………………………...... ! 19! ! Plasma!Science…………………………………………………………………….!………..! 20! ! Transportation…………………………………………………………………………...... ! 21! ! Appendix&I……………………………………………………………………………………………...... ! 22! ! ! Advanced!Manufacturing……………………………………………………………….! 23! ! Agricultural!Products/Food!Production…………………………………………! 25! ! Biosciences/Biotechnology……………………………………………………………! 26! ! Chemical/Petrochemical……………………………………………………………….! 29! ! Energy………………………………………………………………………………………….! 31! ! Forestry!Products…………………………………………………………………………! 34! ! Information!Technology!and!Cybersecurity……………………………………! 35! ! Metal!and!Advanced!Materials……………………………………………………….! 37! ! Nanotechnology…………………………………………………………………………….! 39! ! Plasma!Science……………………………………………………………………………...! 40! ! Transportation……………………………………………………………………………...! 41! Alabama EPSCoR State Science and Technology Roadmap (AESSTR)1 EXECUTIVE SUMMARY Accelerate Alabama, the economic development strategic plan for the state, was led by the Alabama Economic Development Alliance, created in July 2011 by Executive Order of Governor Robert Bentley, and Chaired by the Alabama Secretary of Commerce. Accelerate Alabama, with input from more than 1,200 stakeholders, provides direction for Alabama’s economic development efforts. Accelerate Alabama identified targeted business sectors for Alabama to focus its efforts, as well as recommendations or accelerators, and related tactics, centered on three economic development drivers: Recruitment, Retention and Renewal. The targets and accelerators were identified based on extensive research, as well as input from the Alliance members and other stakeholders located throughout the State. In coordination and in support of the Accelerate Alabama economic development strategic plan, Alabama EPSCoR (ALEPSCoR) has developed the ALEPSCoR State Science and Technology Roadmap (AESSTR). AESSTR was crafted in consultation with the research leaders of the seven Ph.D. granting institutions in the State, representatives from the Alabama Department of Commerce, the Economic Development Partnership of Alabama (EDPA) and with input from research oriented companies such as the Hudson Alpha Institute for Biotechnology and Southern Research. The Roadmap complements Accelerate Alabama by identifying statewide research priorities and areas of research expertise across Alabama’s universities and laboratories that can provide the targeted economic growth. The AESSTR will be regularly updated to reflect evolving research priorities and new areas of research expertise. The AESSTR calls for partnership between the research and education enterprise of Alabama’s universities and economic growth in the state. It describes a pathway for utilizing the skills and resources at Alabama’s universities with private and public laboratories to achieve the goals of statewide Renewal of industry through the growth of innovation and research and development activities directly related to the expertise and strength of Alabama’s universities and laboratories. Alabama has a long history in agriculture, chemistry, forestry, manufacturing and transportation. More recently other domains, including biosciences, informatics technology, space sciences, energy, plasma science, information science and nanotechnology have emerged. A strategic, forward-thinking Alabama can take advantage of these emerging domains of strength to build a thriving, diverse economy. The AESSTR provides the mechanism for Alabama to capitalize on the inherent strengths of its institutions of higher education to bring a renewal to the state, building an environment where science, technology, and the economy grow alongside the intellectual and business opportunities of the future. The AESSTR identifies current technology expertise and planned focus areas in Science and Technology (S&T) at Alabama universities and institutes as well as map this expertise to potential industry sectors, makes recommendations for enhancing and expanding Alabama’s infrastructure, and lists resources needed to “Accelerate Alabama” to ensure the state is nationally and internationally competitive.

1 This AESSTR document was approved and endorsed by the Alabama EPSCoR Steering Committee on 7/21/2016.

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 1

I. INTRODUCTION On a national level, the America Creating Opportunities to Meaningfully Promote Excellence in Technology, Education, and Science (COMPETES) Act was enacted in 2007 and reauthorized in 2010. America COMPETES articulates the need for increased national attention to science, technology, engineering, and mathematics (STEM) education, research, and development. Alabama has long recognized the economic importance of encouraging growth in targeted STEM research areas. Initially, the 2009 Alabama Science and Technology Roadmap (2009 Roadmap) was developed to guide leaders in the public and private sector to ensure the growth of a strong science and technology foundation in Alabama. The 2009 Roadmap identified core technology assets in the state and called for enhancing state and private support for “applying core technologies more extensively to promote innovation and global competitiveness of Alabama’s key industries, such as automotive, , healthcare, agriculture, forest products and advanced manufacturing.” This was followed by the development of a more advanced economic development strategic plan for the State, Accelerate Alabama,2 led by the Alabama Economic Development Alliance, created in July 2011 by Executive Order of Governor Robert Bentley, and Chaired by Alabama Department of Commerce Secretary Greg Canfield.3 Accelerate Alabama includes eleven identified targeted business sectors for Alabama to focus its efforts, as well as recommendations or accelerators, and related tactics, centered on three economic development drivers: Recruitment of new business and industry, Retention and expansion of existing business and industry and Renewal through job creation, innovation and research and development, as well as commercialization. In coordination and in support of the Accelerate Alabama economic development strategic plan, Alabama EPSCoR (www.ALEPSCoR.org) has developed the Alabama EPSCoR State Science and Technology Roadmap (AESSTR). The AESSTR identified statewide research priorities and areas of research expertise across Alabama’s universities and laboratories that provide the targeted economic growth of Accelerate Alabama. Those statewide research priorities identified in the AESSTR are: advanced manufacturing, agricultural/food products, biosciences/biotechnology, chemical/petrochemical, energy, forestry products, information technology and cybersecurity, metal and advanced materials, nanotechnology, plasma science, and transportation. AESSTR was crafted in consultation with the research leaders of the seven Ph.D. granting institutions in the State, representatives from the Alabama Department of Commerce, the Economic Development Partnership of Alabama (EDPA) and with input from research oriented companies such as the Hudson Alpha Institute for Biotechnology (HudsonAlpha) and Southern Research (SR).4 This AESSTR plan, formally approved and endorsed by the Alabama EPSCoR Steering Committee on July 21, 2016, will be updated yearly to reflect evolving research priorities and new areas of research expertise. Education and research organizations contribute directly to economic development efforts and are important for the Recruitment of new business and industry. An important element to Retention of industry is research and development in collaboration with the existing industries in

2 See: http://www.madeinalabama.com/assets/2013/03/AccelerateAlabamaPlan.pdf 3 The Alabama Development Office (described in Reference 2) is now the Alabama Department of Commerce. 4 See: http://hudsonalpha.org, and http://www.southernresearch.org, respectively.

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 2

Alabama. Alabama’s efforts toward Renewal of industry through the development of innovations and research and development activities are directly related to the expertise and strength of Alabama’s universities and laboratories. The AESSTR primarily addresses the support for statewide Renewal. The S&T segment of Accelerate Alabama identifies the vast areas of expertise across Alabama universities and institutes and maps expertise to targeted industry sectors in the State. It is anticipated that this information will help describe a pathway for leveraging the skills and resources at Alabama’s universities and private and public laboratories to achieve the goals of Accelerate Alabama. This document has two areas of focus: 1. Identification of current technology expertise and planned focus areas in science and technology resident at Alabama universities and research institutes and maps these capabilities to potential industry sectors. In addition, institutional primary points of contact are included as well as a detailed spreadsheet outlining institutional capabilities and expertise. 2. Recommendations for implementation of the strategies/tactics posed in the 2016 Roadmap for enhancing and expanding Alabama’s infrastructure and resources needed for Accelerate Alabama to ensure that the state is nationally and internationally competitive.

II. RESEARCH EXPERTISE AND CAPABILITIES A critical step in the effort to support Renewal in Alabama is the creation of a comprehensive database of current programs in research and technological development underway at universities and research institutions in the state. The AESSTR identified statewide research priorities and areas of research expertise across Alabama’s universities and laboratories that provide the targeted economic growth of Accelerate Alabama. Those statewide research priorities identified in the AESSTR in alphabetical order are: 1. Advanced Manufacturing 2. Agricultural Products/Food Production 3. Biosciences/Biotechnology 4. Chemical/Petrochemical 5. Energy 6. Forestry Products 7. Information Technology and Cybersecurity 8. Metal and Advanced Materials 9. Nanotechnology 10. Plasma Science 11. Transportation Institutional research expertise in these priority areas is illustrated graphically in the Alabama Expertise Maps with more detail provided in the Alabama Research and Technology Data Base. a. Alabama Expertise Maps The maps provided in Section VI, pages 11-21, graphically describe the targeted industry sectors and expertise mapping for priority research and technology that support Alabama’s industries. The icons reflect the major research emphases at the Alabama research institutions. More

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 3 detailed information on the specific focuses in each area is provided in the Alabama Research and Technology Data Base, described below. b. Alabama Research and Technology Data Base The research expertise and capabilities data collected from the State’s major research institutions are summarized in greater detail in Appendix I, pages 23-41, in three levels of increasing detail. At the top level, research expertise across the State has been separated into the eleven Primary Target categories described previously. Each of these Primary Target Categories (see first column of Appendix I) is subdivided into several secondary Sub-Target Categories, each distinguished by a separate color (within the Primary Category). Specific institutional research strengths and capabilities are listed by column according to research institution with each specific capability highlighted in the same color as the Sub-Target Category for the State. This Research Capabilities Table will eventually be expanded into an extensive database of major research and development instrumentation and other resources for the State. This will include not only expertise, but also physical resources such as, but not limited to, high throughput screening labs for small molecule drug development, resources for additive manufacturing and the manufacture of advanced composites, and facilities to develop high temperature superconductors. This database will facilitate collaboration between and among universities, government labs and businesses in the State, and help minimize duplication of effort. The establishment and updating of this database will be supervised by members of the Alabama EPSCoR Steering Committee and the EDPA Foundation Board working with the Alabama Commerce Department. This group will track the development of new large-scale collaborative projects undertaken in Alabama. The continuing outcome assessment will be essential to determine the effectiveness of this component of the Renewal effort. III. STRATEGIES FOR ENHANCING COLLABORATION Research institutions throughout Alabama have, from their founding, engaged with their respective communities and regions to address public and private sector challenges. Whether responding to crises like natural and man-made disasters like the BP oil spill in the Gulf of Mexico, addressing societal issues or economic development opportunities, or contributing expertise to a space race that landed a man on the moon, Alabama colleges, universities and research centers have and continue to play a critical role in the state’s growth and prosperity. For more than a century, the talents of higher education faculty and staff have been leveraged to support community development efforts, education, and training. Experts from academia provide technical assistance to targeted populations; support Alabama business recruitment and expansion efforts; conduct industry-sponsored research and development; and make use of business and faculty knowledge to create innovative products that result in commercialization, increased entrepreneurship, and technology transfer. Given their extensive existing infrastructures and tradition of engagement, Alabama’s research institutions are poised to play an ever-increasing role in fostering the state’s flourishing knowledge-based economy through strategic public/private sector interactions. Groundwork for these interactions is already being laid in research parks, business incubators, and workforce development efforts throughout the State. Collectively, we are working to build stronger and better-informed collaborative relationships through extensive engagement with economic developers, civic leaders, state agencies,

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 4

Chambers of Commerce professionals, and other professional organizations across the region with improved economic development outcomes as our goal. The Alabama EPSCoR Steering Committee is one such collaborative organization where the Vice Presidents for Research (VPRs) representing Alabama’s seven Ph.D. granting research institutions meet quarterly with Alabama industry leaders from AT&T Alabama, Southern Research, Alabama Power, Research, and TVA, as well as, leaders from Alabama Commerce Department, the Alabama Commission on Higher Education (ACHE), and the Economic Development Partnership of Alabama (EDPA). The EDPA Foundation Board is another such collaborative organization where many of these same university and government leaders meet quarterly with Alabama industrial leaders. Alabama’s institutions of higher education have maintained continuously positive relationships with their valued external stakeholders and are now poised to explore creative ways to better serve existing partners and identify new ones. Meaningful partnerships and collaborations are currently on-going between Alabama’s research institutions and noted partners such as GE Aviation in Auburn, Group and Austal in Mobile, NASA Marshall Space Flight Center and in Huntsville, and the Mercedes, Honda, and Hyundai automotive plants in Tuscaloosa, Lincoln, and Montgomery to identify a few. We are committed to strengthen external engagement and economic development efforts, and work strategically and intentionally to build the economy of Alabama and the Southeast. IV. GROWTH OF ALABAMA R&D As in industry, universities and laboratories chart their future growth areas. Many of the areas in which universities are investing track well with the Renewal innovations and investments needed by Alabama’s small to large businesses and industries. As an example, listed below are some of the stated areas in which Alabama institutions are increasing their investments in faculty, instrumentation and facilities. As shown on the capability table (Appendix I) many universities and laboratories have already developed extensive R&D capabilities in multiple sectors and with the added capacity, Alabama will expand its support for economic growth. Some examples are: ü Additive Manufacturing/3D /4D Printing: This effort, which could revolutionize low cost, high throughput manufacturing technology for Alabama, has institutional participants including University of Alabama, Auburn University, University of Alabama in Huntsville, University of Alabama at Birmingham, University of South Alabama, Alabama A&M University, Southern Research and Tuskegee University. ü Precision and/or Smart Agriculture: This effort, which could significantly increase Alabama crop yields and reduce costs, includes expertise at Alabama A&M University, Auburn University, University of Alabama at Birmingham, University of Alabama, University of Alabama in Huntsville and Tuskegee University. ü Low Temperature Plasma Science and Technology: This effort, which underpins the existing aerospace and defense sectors, is finding novel applications within multiple areas including the automotive, health, agricultural, food, plasma medicine, nanotechnology and microprocessor, bio-electrochemistry, and optoelectronics industries from experts at University of Alabama in Huntsville, HudsonAlpha, Auburn University, University of Alabama in Birmingham, University of Alabama, Tuskegee University, University of South Alabama and Alabama A&M.

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 5

ü Cybersecurity and Big Data Analytics: This effort, which could make Alabama a leader in analyzing Big Data and reducing the vulnerability of the Nation to cyber-attacks, has experts at Auburn University, University of South Alabama, University of Alabama in Huntsville, University of Alabama at Birmingham, Tuskegee University and HudsonAlpha. ü Biosensor Technology Development: This effort, which could revolutionize biological and medical sensing is primarily centered at Alabama A&M, University of Alabama in Huntsville, Auburn University, Tuskegee University, University of South Alabama, Southern Research and HudsonAlpha. ü Alternative Energy Systems: This effort to make Alabama a leader in renewable energy research has experts at Auburn University, Tuskegee University, University of Alabama in Huntsville, University of South Alabama, Southern Research and HudsonAlpha. ü Transportation: This effort to develop creative solutions for improvements in vehicle safety; design, construction and maintenance of roads and bridges; as well as the impact that a quality transportation system has on the state exist at Auburn University, Tuskegee University, University of Alabama, University of Alabama at Birmingham, University of Alabama in Huntsville and the University of South Alabama. A key component of ensuring the Renewal of Alabama industries is maintaining global competiveness. Innovation through research and development is critical to Alabama’s universities and other research institutions. Equally critical is enhancing Alabama’s R&D infrastructure. Listed below are some of the key resources included in strategic roadmaps at Alabama universities and laboratories. Provided below are examples of one important Statewide priority and several institutional priorities: Statewide Priorities: Creation of the Commercialization Scholars Program: A primary goal of “Accelerate Alabama” is to promote economic development in Alabama over the next several years by recruiting new industry, maintaining and enhancing those already in Alabama, and creating jobs from entrepreneurship, commercialization and research and development. A vital component of this job creation plan relies on using intellectual abilities at Alabama research universities, specifically those seven Ph.D. granting research universities that constitute the Alabama EPSCoR (www.ALEPSCoR.org).

In order to add to the intellectual firepower within the State, Alabama EPSCoR supports the recruitment of outstanding faculty Commercialization Scholars to the Alabama EPSCoR institutions. These new faculty Commercialization Scholars must be nationally recognized leaders in their field and must be recruited from outside the State. It is expected that those new individuals: 1. Either bring with them a substantive research funding portfolio that in itself within one year adds jobs to Alabama’s economy; or 2. Have a documented and demonstrated track record of utilizing their respective intellectual property to create successful new companies and/or licensing agreements.

This Commercialization Scholars program has the potential of leading to substantial economic growth and job creation in the State by bringing in people that either already have a substantial

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 6 research funding portfolio or that have a proven track record of spinning off successful high tech companies.

Institutional Investment Priorities: University of Alabama at Birmingham (UAB): Data and Genomic Sciences Building: Construction of a new research building that will house new investigators studying the genetics underlying personalized medicine and other “big data” subjects and result in an additional $20 million in grants annually and create hundreds of high-paying jobs. Alabama Drug Discovery Alliance: Expand the initiative by UAB and Southern Research (and potentially expand to other State universities) leading to new pharmaceuticals and add a lucrative ongoing new revenue stream to support State medical science initiatives. University of Alabama in Huntsville (UAH): Engineering Research Building: Construction of a new College of Engineering/UAH Research facility to replace the aging Von Braun Research Hall and College of Engineering buildings to enhance and support state-of-the-art research efforts at UAH. Auburn University (AU): Additive Manufacturing Laboratory: Equipment support and staffing to rapidly advance the state-of-the-art Additive Manufacturing Laboratory currently under construction to develop new low cost, high throughput manufacturing technologies. University of South Alabama (USA): USA Environmental Sciences Building: Construction of a state-of-the-art teaching and laboratory building. This will enable the development of solutions to pressing environmental issues, help support and create Alabama’s resilient and sustainable ecosystems, and educate the next generation of environmental scientists and professionals. Nuclear Genome Technology and Research Center: An interdisciplinary research group focused on DNA damage and repair, genome sequencing, big data analytics and mitochondrial DNA in metabolic syndrome. Funds would be used to support recruitment and additional nationally recognized researchers in the field, recruit additional researchers and research grants, and lead to job creation in Alabama. Alabama A&M University (AAMU): Science Building: Construction of a new science building that will be used for science educational activities. Discovery Center: Construct and equip a major co-laboratory where basic Science, Technology, Engineering, and Math (STEM) research activities will be centralized. University of Alabama (UA): Alabama Transportation Institute (ATI): Build on the strengths in surface transportation research directed toward solving many of our nation’s transportation problems, particularly in the area of highway safety, roadway engineering, and automated vehicles. This

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 7

initiative will consolidate several ongoing efforts at UA by providing a single interface to maintain a broad, interdisciplinary focus that will include every academic unit. Alabama Water Institute (AWI): Basic and applied research in water, severe weather, and disaster management to solve national and regional water issues including water resource management, severe weather issues including improvements in warning processes and disaster management for emergency responders. Southern Research (SR): Increased Capabilities for Renewable Energy and Energy Storage: Matching funds over a 3-year period to enhance the infrastructure being established for grid-ready energy storage, creating jobs for testing and development of new technologies. Bioscience Discovery Building: Matching funds for construction of a new research building on the SR campus to replace fifty-year-old buildings to recruit new Principal Investigators and teams who will drive innovations in infectious disease (including Zika), oncology and Central Nervous System (CNS) disorders via commercial clients, grants and new drugs. Tuskegee University (TU): New Research Building: Perform cutting edge research that will lead to new start-up businesses for the State. Student Endowments: Tuition support and stipend for 10 graduate students per year and salaries for five postdoctoral fellows per year to support cutting edge research that will create new jobs for the State. Hudson Alpha Institute for Biotechnology (HudsonAlpha) Genomics and Pharmacogenomics Core: Provide whole genome sequencing for Alabamians with a rare disease while enhancing the scientific prestige. This program may reduce the cost and make Alabama the first state to offer whole genome sequencing to all babies by 2021 through a combination of government, self-pay, insurance and philanthropy. "Correct Care Initiative": Provide genome sequencing for the elderly and offer cutting edge care to senior citizens of Alabama and make Alabama a hub for pharmaceutical companies interested in developing new targeted medical treatments. The funding would allow HudsonAlpha to provide genomic analysis for known genetic markers and work with commercial partners to develop new ones.

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 8

V. INSTITUTIONAL POINTS OF CONTACT

The following institutional points of contact can provide additional information about that institution’s S&T plan and research capability.

Institutional Points of Contact Provost, VP for Academic Affairs, Interim AAMU Daniel Wims VP for Research, Economic Development 256-372-5275 [email protected] and 1890 Programs Interim Executive Director, Research and AAMU Xiaoqing Qian 256-372-8187 [email protected] Sponsored Programs Dean - College of Engineering, Technology, AAMU Chance Glenn 256-372-5560 [email protected] and Physical Sciences Vice President for Research and Economic AU John Mason 334-844-5977 [email protected] Development Executive Director, External Engagement AU Larry Fillmer and Support and Interim Executive Director, 334-844-6140 [email protected] Auburn Research & Technology Foundation Hudson Intellectual Property and Industry Andy Crouse 256-327-9623 [email protected] Alpha Partnership Development, Research Affairs Hudson Carter Wells Vice President for Economic Development 256-327-5241 [email protected] Alpha SR Art Tipton President and CEO 205-581-2664 [email protected] SR Watson Donald Director, External Affairs 205-581-2641 [email protected] Vice President for Research and Dean of TU Shaik Jeelani 205-727-8970 [email protected] Graduate Studies VP for Research and Economic UA Carl Pinkert 205-348-4566 [email protected] Development UA John Higginbotham Associate VP for Research 205-348-7259 [email protected] Vice President for Research and Economic UAB Richard Marchase 205-934-1294 [email protected] Development UAB Kent Keyser Assistant Vice President for Research 205-934-7757 [email protected] Vice President for Research and Economic UAH Ray Vaughn 256-824-6100 [email protected] Development Director, Office of Technology UAH Kannan Grant 256-824-6621 [email protected] Communication Vice President for Research and Economic USA Lynne Chronister 251-460-6333 [email protected] Development Director of Commercialization and Industry USA Andy Byrd 251-460-6384 [email protected] Collaboration

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 9

VI. RESEARCH EXPERTISE AND CAPABILITIES MAPS

The maps in the following pages graphically describe the targeted industry sectors and expertise mapping for research and technology that support Alabama’s industries. The icons reflect the major research emphases at the Alabama research institutions, separated into eleven Primary Target categories: (listed in alphabetical order): Advanced Manufacturing Agricultural Products/Food Production Biosciences/Biotechnology Chemical/Petrochemical Energy Forestry Products Information Technology and Cybersecurity Metal and Advanced Materials Nanotechnology Plasma Science Transportation

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 10

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 11 Agricultural Products/

Food Production HudsonAlpha AAMU AU HudsonAlpha Alabama Auburn Institute for A and M University Biotechnology University

TU UA UAB Tuskegee University of University of University Alabama Alabama at Birmingham

AAMU UAH USA SR University of University of Southern Alabama in South Alabama Research Huntsville

HudsonAlpha UAH

Genomics & Precision Biotechnology UAB Agriculture SR

Modeling - Soil, Food Processing AU Climate & Water Nutrition & Packaging UA

TU Fisheries & Agricultural Waste Aquaculture Management

USA

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 12

Biosciences/

Biotechnology HudsonAlpha AAMU AU HudsonAlpha Alabama Auburn Institute for A and M University Biotechnology University

TU UA UAB Tuskegee University of University of University Alabama Alabama at Birmingham

AAMU UAH USA SR University of University of Southern Alabama in South Alabama Research Huntsville

HudsonAlpha UAH

Biomedical Pharmaceutical Patient Care & Genomics Development Clinical Research & Informatics UAB SR

Biomarker Disease Models Systems Discovery Biology

AU UA Protein Chemistry & Remediation & Biomedical Devices Engineering Waste Managment & Materials

TU Marine Molecular Agricultural Pharmacology Medicine Genomics & Informatics

Waste Water Plasma Treatment USA

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 13 Chemical/

Petrochemical HudsonAlpha AAMU AU HudsonAlpha Alabama Auburn Institute for A and M University Biotechnology University

TU UA UAB Tuskegee University of University of University Alabama Alabama at Birmingham

AAMU UAH USA SR University of University of Southern Alabama in South Alabama Research Huntsville

HudsonAlpha UAH

Analytical Chemical Petroleum Chemistry Engineering Remediation & Managment UAB SR

Computational Carbon Catalysis Chemistry Sequestration

AU UA

Environmental Surface Polymer & Material Chemistry & Chemistry Chemistry Toxicology

TU

Crystallography Biochemistry

USA

Medical Chemistry

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 14

Energy HudsonAlpha AAMU AU HudsonAlpha Alabama Auburn Institute for A and M University Biotechnology University

TU UA UAB Tuskegee University of University of University Alabama Alabama at Birmingham

UAH USA SR AAMU University of University of Southern Alabama in South Alabama Research Huntsville

HudsonAlpha UAH Propulsion Systems Power Grid Technology

UAB SR Energy Storage Biofuels

AU UA Wind & Solar Pollution Control

TU Hydrocarbon Energy Modeling & Engineering

High Temperature Plasma Materials USA

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 15 Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 16 Information Technology

& Cybersecurity HudsonAlpha AAMU AU HudsonAlpha Alabama Auburn Institute for A and M University Biotechnology University

TU UA UAB Tuskegee University of University of University Alabama Alabama at Birmingham

AAMU UAH USA SR University of University of Southern Alabama in South Alabama Research Huntsville

HudsonAlpha UAH

UAB Bioinformatics Security SR

AU Big Data Artificial Intelligence UA Machine Learning

TU Modeling & Image Software Processing Engineering

USA

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 17

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 18 Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 19 Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 20 Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 21 APPENDIX I ALABAMA RESEARCH AND TECHNOLOGY DATA BASE The Alabama Research and Technology Data Base summarizes the research expertise and capabilities data collected from the State’s major research institutions, in three levels of increasing detail. At the top level, research expertise across the State has been separated into eleven Primary Target categories (listed in alphabetical order): Advanced Manufacturing Agricultural Products/Food Production Biosciences/Biotechnology Chemical/Petrochemical Energy Forestry Products Information Technology and Cybersecurity Metal and Advanced Materials Nanotechnology Plasma Science Transportation Each of these Primary Target Categories (see first column) is subdivided into several secondary Sub-Target Categories, each distinguished by a separate color (within the Primary Category). Specific institutional research strengths and capabilities are listed by column according to research institution with each specific capability highlighted in the same color as the Sub-Target Category for the State. As an example, the first Primary Target Category is Advanced Manufacturing (see Page 23). The first Sub-Target Category under this Primary Target is Modeling and Simulation in blue, with specific research capabilities listed under AAMU (second column), AU (third column), TU (forth column) and UAB (sixth column).

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 22 Alabama Research Target Areas - Capabilities started Sept 2017, revised May 2018; revised July 2019 Primary Target Secondary, sub-target areas Areas HudsonAlpha update AAMU No changes ASU no changes as of TU (no updates per Jeelani UA update 7/29/2019 CN UAH updated 7/29/2019 USA updated 7/29/2019 SR update 7/29/2019 CN AU (added 8/22/19) UAB 7/29/2019 CN 2 √ required 8/8/2019 9/2/19) 2√ CN 2 √ CN 2 √ had questions

Alabama Life Research Plant Genomics/ Genetics Agricultural Biotechnology Plant Genetics Institute

Vaccine design/molecular Plant Genome Sequencing therapeutics (applicable to Molecular Genetics/ Biology Genomics and Biotechnology bovine & avian systems)

De novo assembly of complex plant genomes

Microirrigation and Precision Ag Enhanced Water Use Urban Greenroof multispectral remote sensing Efficiency Precision Agriculture

Disease / Pest Management Food Production

Soil/Climate Modeling Alabama Water Institute Atmospheric Science Atmospheric Science

Center for Complex Modeling - Soil, Climate and water resource management Water Hydrosystems Research

Remote Sensing Center

Food Processing/ Enhanced Novel Food Vitamin B Supplements and chemical and biochemical Food Chemistry and Safety Food Production Food production Engineering/ Packaging Products Nutrition testing

Toxicology and reproductive Sustainable Organic Plant Nutritional Biochemistry Food defense Nutrient Flow sensing Nutrient flow sensing toxicology testing of new and Animal Production additives and ingredients. Food Processing Nutrition and Packaging

Food Chemistry and Safety Sustainable Animal Feed

Alternative Dietary Protein

Integrative evolutionary Aquaponics and water science Urban Aquaculture Aquaculture ecology

Sustainable Water Usage Fisheries Fisheries and Aquaculture Agricultural Products/ Food Production

Water/Wastewater Treatment

Agricultural Waste Poulty manure to products Management Agricultural Waste Management Bioenergy and Biofuels, Water/Wastewater Treatment; Solid Waste Mgt.

Nanoparticle treatment for Low Temperature Plasma Surface Chemistry polymer filler compatibility HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Dynamic behavior of various Alabama Life Research Medical Genomics Nutrigenomics prey-predator models with Omics / Informatics Gene discovery Bio-informatics Genomics/Transcriptomics Microbial Metagenomics Institute delays

Bioinformatics and Data Silver and gold nanomaterials Molecular Medicine Alabama Water Institute Genomics Genetics Population Genetic Analysis Analysis for infectious diseases

Genomics Genomics Immunotoxicology Immunogenomics Pharmacogenomics Plant Genomics Retrospective, population- scale analyses of drug efficacy, Biomedical Genomics and drug safety, and public health microRNA Technologies Informatics

Novel Reagents to Assess Microbiomics DNA Damage and Repair

Silver Nanoparticles in Skin Biophysics Cancer Prevention

Single cell transcriptomics DNA mechanics (p. 1 of 3) of 1 (p.

Drug Delivery

Nanoscale materials and Protein Structure and 1 Million compound library Pharmaceutical Engineering Drug Delivery Drug Delivery Drug Discovery biointegration Characterization for new drug analysis

Nanomaterial based Computational Drug HTS (High throughput Drug Discovery / Drug Delivery Nano-biomedicine Biomaterials MCI Cancer Therapeutics diagnostic systems Discover screening) capabilities

NMR Characterization at Medicinal/organic chemical Drug target Alabama Life Research Central AL High-Field NMR Antimicrobial Development Local drug delivery systems synthesis and combinatorial identification/validation Institute Facility design Assay development and Drug metabolism and Medicinal chemistry validation for clinical trial Pharmaceutical Development disposition capabilities Candidate molecule Drug Trials - O'Neal FDA regulated preclinical optimization (medicinal Comprehensive Cancer Cnt capabilities chemistry) (CCC)

Infectious disease screening

Biosciences/ Biotechnology for new drugs and vaccines including biothreat

Preclinical toxicology

Genome sequencing, Drug Delivery Precision Diagnostics genotyping, and analysis

Additive manufacturing, for Pharmacogenomics Genomics custon implants

Precision Medicine Personalized Therapeutics

Drug Development

Precision Oncology

Pharmacogenomics HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Pharmaceutical care outcomes Alabama Life Research Arthritis and autoimmunity Diabetes and Insulin MCI Clinical Trials - Phase I, II, Personalized Medicine research Institute diagnosis and treatment Resistance III, IV

Retrospective, population- scale analyses of drug efficacy, Diabetes and obesity Opiod abuse and drug Microbiota and Cancer Clinical Genomic Medicine drug safety, and public health research, nutrition, and Drug Delivery interventions Therapy clinical care

Interventional clinical trials Institute for Rural Health Disability Health and Rare Diseases Biomedical imaging Research Rehabilitation Science Drug metabolism and Center for the Prevention of Basic and clinical studies of Polygenic Risk Scores Cell culture disposition Youth Behavior Problems aging Biofluid mechanics pulmonary diseases Clinical imaging

Exercise interventions (e.g., hypertension, vascular Health Disparities research CMR (cardiovascular inflammation, blood pressure) magnetic resonance imaging) Patient care and clinical Patient outcomes and Cardiovascular devices, research comparative effectiveness mechanics, pathology:

Exercise biology and Echocardiography medicine

Infectious diseases Endoscopy

Visual and oral systems Fluorescence imaging

Cancer care - O'Neal Heart failure Comprehensive Care Cnt

Neurological Diseases Human thermoregulation

Transplant Medicine Hyperspectral imaging

Local drug delivery systems Magnetic resonance imaging (MRI)

(p. 2 of 3) of 2 (p. Tissue engineering

Cancer Diagnosis and Biomarker ID for Human Biomarkers for the Detection biomarker assay Bio-scaffolds Bioinformatics Prognosis Disease of Ovarian Cancer development and validation

Biomarker Discovery Drug Response and Alabama Life Research Genome Transcription Biomarkers for the Detection Pharmacogenomics Institute Factors of Pancreatic Cancer

Cell Free DNA Analysis Tissue Engineering

Tumor models/ cancer In vivo model systems of Relevant models in cancer, progression and therapy Neurological Diseases Cancer and Health Disparities disease and drug action CNS, infectious disease mechanisms

Alzheimer's and Parkinson's In vivo imaging Autoimmunity Microbiota and Cancer Immuno-oncology models Disease

Biomolecular modeling and Virology Autism Diabetes simulation

Biosciences/ Biotechnology Amyotrophic Lateral Sclerosis Cancer Cardiac strain (ALS)

Cystic Fibrosis Aging Cell signaling modeling

Cystic Fibrosis Collective cell migration

Disease Models Cardiovascular Disease Heart failure

Sickle Cell Human thermoregulation

Bone Disease Radiation (biological effects)

Obesity

HIV/AIDS

Pulmonary Diseases (p. 2 of 3) of 2 (p. Biosciences/ Biotechnology

Disease Models

Hypertension

Kidney Disease

Reproductive Physiology/ Alabama Life Research Biomolecular modeling and Cancer Biology Microbiology Computational biology Biomedical Informatics Evolutionary Biology Endocrinology Institute simulation

Systems Biology Brain and Nervous System Lipid Biotechnology Cancer Biology Molecular Genetics/ Biology Computational Genomics Microbiology Biophysics Metabolic Systems Plant Molecular Biology Structural Bioinformatics Molecular Biology Bioreactor systems

Cardiovascular Disease Structural Biology HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Computational protein design Protein chemistry and Traditional and Novel Synthetic vaccines Protein Function and engineering enzymology Adsorbents Protein Chemistry and Engineering X-ray and Neutron Metallobiochemistry Crystallography

Protein modeling, design and Biological Waste Alabama Water Institute control Management

Microbial Remediation Remediation and Waste Management Water/Wastewater Treatment

Bioremediation, Solid Waste Mt

Device development for Forensic Drug Analysis Bio-sensors and Recognition Bio-tissue mechanics Wireless Biomedical Devices Hyperspectral Imaging Medical device engineering patient rehab

Biomedical Device Technology Bio-robotics and prosthetics Biosensors Theranostic Nanostructures Biomedical Devices

Alabama Life Research Ultra-hard Coatings for Biomechanics Hyperspectal imaging Biomedical Devices and Institute artificial joints Materials Additive manufacturing for New Dental Implant Materials Bio-composites orthotics, implants

Optical imaging (ALIAS) Cardiac Implants Bio-electromagnetics

MRIRC (3T/7T functional MRI) Orthopedic Implants Nano-medical technology

Ophthalmology Implants (p. 3 of 3)

Marine Pharmacology Marine Pharmacology

Broad Genomics and Molecular therapeutic platform Alabama Life Research Novel microbiological Genetics in Clinical and design (AAV-/linear phage- Molecular Medicine Institute approaches Research Approaches based)

Center for Water Quality Waste water treatment Waste Water Treatment Waste Water Treatment Research Waste water treatment Waste water treatment/ concrete wash water alkalinity

Plant Genomics/Genetics Plant Genomics/Genetics

Agricultural Genomics and Plant Genome Sequencing Genome Sequencing Informatics De novo assembly of complex plant genomes Biosciences/ Biotechnology

Nanobiotechnology, Nanoparticles as Nanoparticles based cancer Plasma dynamics/ Plasma Surface Modifiations Plasma Biology and Medicine Cancer Treatment Low Temperature Plasma antimicrobials, NPs as drug, treatment diagnostics of Vascular Grafts vaccine delivery agents

Neuroscience and neuro behavioral assesments CNS Plasticity neuroimaging for in vivo preclinical studies

Neurology Learning and Memory

Genetic Diseases

Rehabilitation Sciences and Biology of the Heart and Services, including the Rise Low-intensity ultrasound other organs Center

Restorative Medicine (p. 3 of 3)

Biosciences/ Biotechnology

Tissue Engineering and Assistive technologies Nanoengineering Restorative Medicine Engineering of Artificial Organ Products

Patient care: Transplantation of Bone Marrow or Tissue/Organs HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Carbon fuels and other Forensic Drug Analysis Small Molecule Synthesis Organic/inorganic synthesis Chemical Synthesis Analytical Analytical Chemistry chemical analysis

In situ/operando spectroscopy Chemical analysis Inorganic Chemistry Natural Chemical Synthesis Environmentally Benign Analytical Chemistry Central Analytical Facility Chemical Analysis Solvent Systems Metal-organic frameworks

Chromatography

Functionalized membranes Process Control and Chemical Engineering Transport Processes for separations and reactors Automation

Molecular thermodynamics

Microcontinuum fluid mechanics

Chemical Engineering Reactive chemical systems

Solution chemistry

Separation of nonpolar species

Solid-liquid mass transfer

Bioremediation, Oil Spill Management Petroleum remediation and Water/Wastewater Treatment management Petroleum Chemistry

Computational protein design (p. 1 of 2) of 1 (p. Computational chemistry Computational chemistry Protein Docking Monte Carlo methods and engineering Computational chemistry Molecular dynamics and simulations

CO2 capture and storage, Carbon Sequestration CO2 utilization adsorption, membrane CO2 sequestration Ionic Liquids separation Design and analysis of Artificial Photosynthesis Heterogenous catalysis Heterogeneous catalysis Catalysts and sensors Solar Fuel Catalysts Sensors catalysts

C1 catalusis Heterogenous Catalysts Supercritical Fluids

Phase - Transfer Catalysis

Noble metal catalysts

Chemical / Petrochemical / Chemical Phase-transfer catalysis

Activated carbons Catalysis

Supercritical fluids

Zeolites (p. 1 of 2) of 1 (p. Chemical / Petrochemical

Catalysis

Mesoporous materials

Microporous materials

Physical activation and adsorption

Biochemical and Molecular Environmental Chemistry and Remediation of petroleum Ionic Liquids Toxicology Toxicology contaminated soils

Ionic Liquids

Environmental Chemistry and Volatile organic compound Toxicology (VOC) emissions

Ionic liquids

Pharmaceuticals in the environment; Pharmaeutical bioremediation

Raman Spectroscopy Studies Surface Chemistry Surface Chemistry Absorption of Bioactive Materials

Surface Chemistry Adsorption

Multicomponent adsorption HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Polymer chemistry- Nanoparticle catalysis, nanoparticle synthesis, Polymer coated metal cellulose deconstruction, Polymer chemistry, materials Polymer material science Polymers Materials Chemistry nanoparticles and nanotubes small molecule synthesis and chemistry Polymer and Material characterization; plant derived extracts; bioactive Chemistry compound synthesis

Polymeric Materials for

(p. 2 of 2) Water Purification

polymer coatings Bionanotechnology

Small Molecule Crystal Growth Chemical Oceanography Crystallography Crystallography Protein Crystallography for Crystallography Drug Design

Nanotechnology for Biochemistry Photosynthesis Biochemistry Biomedical sensing

Computational protein design Alabama Life Research Drug Design and Adhesive Joints for Natural Products and engineering Institute Development Composite Materials

Medical Chemistry Novel Chemical Development Medicinal chemistry of Cancer treatment, Chemical / Petrochemical / Chemical diagnosis and analysis

Microwave Plasma Synthesis plasma induced Plasma Induced chemical Combustion For Micro- Low Temperature Plasma and Processing of superhard nanoparticles synthesis reactions Thrusters Materials HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Water management and Water Resources Water Resources Hydrology treatment

Sea level rise Water Resources Living shorelines

Coastal resilience and vulnerability Sustainable, healthy wildlife Wildlife Management Environmental Engineering Insect Phermonology populations Aquatic Ecology Carbon Sequestration Genetics Environmental monitoring Forest fire fighting Environmental Health for Combustion Wetlands technology Humans Control of animal and plant Volatile organic compound Environmental Health and Forest Ecology invasive species (VOC) emissions Modeling Pharmaceuticals in the Modeling of climate influences Ecology environment; Pharmaeutical on forests, wildlife, and people bioremediation

Socioeconomic factors

Plant Functional Expanding products, reducing Biomass sugars to chemicals Wood Products Technology Lignocellulose extraction Sustainable Energy Natural Products Chemistry Biomass dissolution Genomics/Genetics manufacturing costs process technology

Lowering transportation costs biomass to liquid fuel Forestry Products Plant Genome Sequencing Biofuels Biopolymers Alternative Fuels Fermentation Bioenergy and biofuels for bioenergy feed stocks process technology

De Novo assembly of Metabolic engineering for Liquid biofuels/ combustion Biocomposites Biofuels and Products complex genomes energy production technologies

Bioenergy/ Biorefinery Technologies, Pulp and Paper Process Engineering

Biodiesel from vegetable oils with honeycomb monolithic catalysts

Remote Sensing Center Weather/Climate Models Atmospheric Science Atmospheric Science HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Analysis of Chemical Surface characterization of Plasticity and dislocation Surface and other capabilities Mechanical Property Testing Forensic Drug Analysis In situ/operando spectroscopy Structure Physical/ Optical Polymers, Ceramics, and Dynamic fracture mechanics dynamics for characterization Function Metals

Chemical Property Analysis low-temp epitaxial growth of Optical/ Nonlinear Optical Void and defect Crystal Growth and Testing semiconductors Testing characterization

material detection and Extrusion classification

Monolayer mechanics and stress microscopy

Development and Testing of High magnetic materials Magnetic materials Nanostructured Superconductors Superconducting Materials

Low cost carbon and, natural Process and Fabrication (metal Material Processing Metal coatings and corrosion Materials Chemistry fiber materials, reinforced Material Science Steel Structural Engineering casting and microjoining) ceramics Welding and repair of rail (p. 1 of 2)

Biodegradable Composite Lanthanide and Actinide steel and thick section Solid State Chemistry Bioprocesses Materials Chemistry structures Characterization of high-Z Integrated computational Advanced Metal Casting Structural Engineering materials materials engineering Technology

Metal casting and Metasurfaces and Fracture and failure analysis Friction Stir Welding Materials Processing and solidification metamaterials Chemistry Micro/nano-fluids and Reliability and failure Analysis suspensions

Microporous materials

Polymer composites

porous media

Adaptive (bio, acoustic wave, semiconductor thin film Alloy formulation and Semiconductors, complex Composite fabrication Advanced Composites and electrochemical) Sensors techniques characterization materials capabilities Metal and Advanced Materials

Smart Nanomaterials and Metamaterials for wireless flexible electronics Spintronic materials Smart Buildings Nanocomposites sensing

HLSA cast material, 7000 Carbon materials Quantum Dots Smart Materials series as cast aluminum

Low RE containing Two-dimensional quantum magnesium alloys, materials computational alloy design

Micro and nanostructure characterization

Surface modification of Plasma erosion of surfaces, nanoparticles, metals metal Surface Interactions, Low Low Temperature Plasma atomic processes at plasma- surface treatment oxides, alloys and polymer work function materials surface interfaces for compatiblity HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Optics and electro-optics Electronic and optical Laser-based optical methods Photonics and biophotonics Optics Tight Binding Models Electrical Insulation manufacturing under ISO and materials TS for military applications

wide band-gap semiconductors, metal-oxide Defects in semiconductors material Electronic and optical Dielectrics (p. 2 of 2)

materials Electrorheological fluids

Magnetorheological fluids Insulation

SAW (surface-acoustic wave) electronic devices

Materials under extreme Full Materials High Temperature Materials High strength low alloy steels pressure and electromagnetic Superconducting devices Characterization Capability at fields extreme temperatures Extreme materials

High temperature ceramic materials

Full Materials Laser Treatment New Coating Technologies Surfaces and Interfaces Characterization at extreme Materials treatment temperatures

Ion-bombardment UV Processing Metal and Advanced Materials

Nuclear Material Safety Nuclear Material Safety HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Modeling and Adaptive Automotive Process, Systems Extrusion compression Modeling and Simulation Control of Electromechanical Modeling and Simulation and Data Analysis molding, injection molding Modeling and Simulation Systems Manufacturing process simulation

3D Scaffolds for infectious Production and Additive manufacturing, 3D Printing with 3-D printing / additive Additive manufacturing of 3-D Printing/Additive disease testing and tissue Printable Electronics characterization of metals, polymeric Biocompatible Plastics manufacturing biomedical implants Manufacturing regeneration composites, and polymers

Additive manufacturing Additive manufacturing, metals In-space manufacturing Additive manufacturing Supply Chain Manufacturing (metals)

Manufacturing process Cyber Security for additive Additive manufacturing Robotics optimization and cost Lean Manufacturing manufacturing (polymer composites) (p. 1 of 2)

minimization Additive manufacturing

UAVs for infrastructure Additive Manufacturing Three-dimensional printing safety and monitoring

Three-dimensional integrated- circuits (3D ICs)

Compound semiconductors

Smart materials for tissue polymeric composites, fiber Composite characterization, Lightweight composites for Composites for Aerospace Composite fabrication Nano Materials Concrete Science engineering reinforced composites development and processing automotive and aerospace Applications capabilities

Long fiber reinforced Intelligent and Virtual Optics and electro-optics High-temperature polymer New electronic and magnetic Advanced Manufacturing Polymers thermoplastic materials Polymers Manufacturing for manufacturing under ISO and composites materials processing Composite Materials TS for military applications

Organic electronics and Electrospinning Green Manufacturing Microfibrous materials Advanced Materials

Cellulose Nanofiber Induction melting efficiency Extraction

Highway safety (roadside Advanced manufacturing barriers)

Carbon fiber reinforced polymer (CFRP)

Bio-composites

Nano- and microparticle Surface treatment, Surface Low Temperature Plasma Surface engineering Surface treatment Deposition surface treatment formation and control ablation HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Cyber security for critical Cyber Security for additive infrastructure Alabama Cyber Institute Cybersecurity Supply-Chain Security manufacturing Interdependency and Security cascading

Cyber security of Cybersecure Electronics

(p. 2 of 2) Trusted Supply Chains Manufacturing Databases Manufacturing

Tribology, wear and coatings Tribology Tribology, wear and coatings Coating Technologies Full testing capabilities

Micro-Fabrication and Rapid Model-based systems Prototyping with Multi- Joining technology Spacecraft thermal systems Industrial Control Systems Steel Structural Engineering Full testing capabilities engineering Materials

Engineering Lighter Weight Electromechanical systems Composite Based Heavy Systems Engineering Truck Components Systems Engineering Systems Engineering of Embedded systems Advanced Robotics Composite Based Auto parts

Development of light weight Manufacturing metrology composite armor for the Army and Navy

Electromechanical, Optical Laser-based optical diagnostic pods, turrets, and stabilized and Infrared methods gimbal systems Advanced Manufacturing HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Bioinformatics and Data Bioinformatics Bioinformatics Biometrics Analysis

Software engineering, reliable Security and Privacy, Wireless and secure software Cyber Vulnerability Assessment Networks, Cyber Physical Alabama Cyber Institute Cryptography Software Safety Smart Grid development Systems

Software reliability and User and Device Cybersecurity UAV Security UAS Security Server-Area Networking security Authentication

High performance computing Industrial Control System Network security Mobile Device Security Embedded Systems intrusion detection Security (SCADA)

Cyber security for advanced Automotive security/ smart Vehicle Cyber Security Digital Forensics manufacturing car research

Device Design for Cyber (p. 1 of 2) Homeland security Security, Signal Processing, Software Protection Embedded Systems

Digital Forensics and Cyber security for IOT Cloud Security Security Cybercrime Investigation Cyber identity protection and Financial Service Security Cyber Physical Systems privacy

Blockchain and Security of 3D Printing Cyptocurrencies

Cloud Computing Security Voting Systems

Security of Internet of Things Insider Threats

Quantum Computing Supply-Chain Security

Malware Analysis

Electronic Medical Device Security

Mobile Device Protection

Cyber security Reliable and secure software Big Data Big Data Internet of Things Big Data Analysis Data analytics Big data analytics Data mining Neural networks development IOT - building sensors for High-performance Biological meta analysis Data Mining Big Data Data Mining Data Mining Big Data Big Data facilities management computing Information Technology andCybersecurity Technology Information Analytics for Forensics, Bioinformatics and Study Data Mining- using Tableau Cybercrime, and Biomedical Design and Power BI Applications Data Visualization

Artificial Intelligence, Artificial Intelligence Machine Machine learing for robotic Agent-directed simulation Machine Learning, and Smart Machine learning Machine Learning Machine Learning Learning platforms Health Networks Artificial Intelligence Identity science AI-Signal Processing Ontology Machine Learning Neural networks

Neuromorphic computing

Intelligent computing hardware HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Signal/Image Processing, Imaging processing and Geographic information Clinical Information Modeling and Simulation Sensor Data Analytics, Control Theory Optimization algorithms analysis systems Extraction Intelligent Systems

VR/MR applications for Statistical Signal and Image building inspection, Alabama Cyber Institute Image/Video Processing Image Processing Optimization of systems Processing Modeling and Image maintenance & safety Processing Modeling and Simulation of Drone technology for buildings Systems (Communications, Scientific Visualization Modeling and Simulation Hyperspectral Imaging Bio, UAV, Vehicles) (p. 2 of 2)

Automatic Target Detection Shape Modeling Visualization and Graphics and Tracking

Genomics Analysis Pipeline Center for Software Software Engineering Software Engineering Distributed Software Systems Software Engineering Development Engineering Clinical Genomics Software Secure Software Gaming Software engineering for CLIA certified use Development Bioinformatics and Data Software Systems for Analysis Massive Datasets Cybersecurity

New Programming Languages Software metrics

Information Technology and Technology Information High speed imaging and image processing Low Temperature Plasmas High performance computing of atomic processes in plasmas HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Energy Device Combustion in rocket Internal combustion engines Power Systems Characterizations engines

Advanced vehicle systems Propulsion Electric sails and components

Traditional and alternative Supersonic vehicles Propulsion Systems fuel combustion

Space propulsion systems

Unmanned aerial vehicles

Distributed co-operative Optimization of electric power Building energy and HVAC control, optimization and Smart Grids Smart Grid Batteries for grid storage systems systems stability of power systems

Particle swarm optimization Gas Turbine Technology / Alabama Cyber Institute

(p. 1 of 3) applied to power systems Power Generation

Renewable energy integration Micro grid power and micro-grid simulations distribution Energy

Smart grid data analysis Smart grid

Power Grid Technology Dynamic Co-operative Distributed Control and Optimization of Power Flexible power management Systems with Integrated devices Renewable Energy Systems Using Game Theory

Particle swarm optimization test bed for power loss in Virtual power plants transmission lines Hardware-In-The-Loop Simulation of Power Wide area power monitoring Systems/Smart Grid Real-time Statistical Analysis Inductive power transfer of Smart Grid Data (IPT) Power management devices Power systems Pulsed power HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Thermal management for Fuel Cell Science and Chemical approaches to Batteries and Advanced Solar and energy storage for Artifical Photosynthesis Solid oxide fuel cell materials Natural Gas Storage battery systems Technology energy storage Energy Storage grid-ready

Conversion of water into Repurposing of electric Energy systems modeling Industrial Control Systems Hydrogen Storage hydrogen energy vehicle batteries Power system protection and Thin film Super-capacitors, control, fault detection Ionic Liquids Lithium process technology Light weight energy storage hardware

Energy Storage Modeling and High temperature energy Simulation for Renewable Home Energy Monitoring storage using sorbents Energy Systems

Radiant Heat Control for Battery Technology Energy storage Solar HVAC Application Dynamic Analysis Tool for Rapid Charging Technology Renewable Energy/Grid Synthetic natural gas Energy storage and harvesting Direct energy conversion

Renewable energy Thermoelectric power generators

Batteries for electric vehicles (p. 2 of 3)

Cellulosic crop and biomass Bioenergy Production and Bioreactors for fuel and fine Microbiological energy Energy Efficiency & Biofuels (Diesel) Photosynthesis Biomass Processing Biomass gas to liquids genomics Bioproducts chemical production production Environmental Sustainability

Growing and harvesting Plant Genomics/Genetics Biomass Production Alternative fuels Biofuels Bioenergy and biofuels Bioenergy fuels

Energy Biofuels Plant Genome Sequencing Biogas conversion Renewable natural gas

De novo assembly of complex plant genomes

Conversion of solar energy, Photon and Particle Sensing Testing and Optimization of Solar Energy Production Wind and solar engineering mechanical energy, chemical Photovoltaic materials Multijunction solar cells Technology commercial panels into electrical energy

Wind/photo-voltaic (PV)/fuel cell modeling, simulation and Solar/Wind/Hydro Modeling Radiation-hard solar cells control

Wind and Solar Hardware validation of PhotoElectroChemical (PEC) Wind/PV/Fuel Cell-Grid hydrogen production Models

Wind and Solar Modeling Photovoltaic devices and Energy Prediction

Renewable Energy, Power Systems Analysis HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Broad range of technology Biogas conversion Carbon Capture and testing for air pollution control from fossil fuels

Carbon capture at power Erosion and sediment control Ionic Liquids Pollution control plant stage (Wilsonville, AL)

Wastewater Treatment; Fuel and chemical Bioremediation; Solid Waste production for waste Mgt streams

Hydro-carbon energy Hydrocarbon Systems Combustion Petroleum Geology Hg testing from fossil fuels

(p. 3 of 3) of 3 (p. Full Modeling and Process Population, system testing Process intensification Engineering Thermodynamics and Fluid Building energy simulations Mechanics Modeling and Engineering Modeling and Simulation Energy

Civil Engineering

Full Materials High Temperature Materials High Temperature Materials Characterization Capability at extreme temperatures

Satellite Propulsion, Space Electric propulsion, plasma Low Temperature Plasma Plasma Radiation Thermal properties of plasmas Small Satellite Propulsion systems assisted combustion HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Novel Nano-Composite Nanomaterials for bacterial Engineered Nanoporous Material Processing Nanomaterials Development and Nano-phase stability Nanocomposites Nano- & Micro fabrication pathogens Materials Application

Polymer Nano-Composites Nanostructure Nanomedicine and Their Applications Functionalized Fibers Nano material Composites and Fabrication Nanocomposites

Nano-medical technology

Nano/micro-fluids and suspensions

Capabilities for production Silver and silver CNT Alabama Life Research and testing of drug products Laser Treatment composites for infectious Tissue Engineering Bionanotechnology Institute (SLN, nano and diseases Therapeutics and Drug microparticles) Delivery Nanoparticle-based drug Metal core nanomaterials Antimicrobial peptides delivery and biomedical (cancer therapeutics) imaging

Food Packaging Food Packaging

Nanotechnology-based Plasmonic and Liquid Crystal Forensic Drug Analysis Bio Sensing Sensor technology Sensor Technology Imaging capabilities sensing sensing Sensor Technology Micro- and nano-scale sensors Nanoenabled biosensors Microfluidics Mechanical Force Sensors and electronics

Nanostructures and Nanofibers Inorganic nanomaterials Silicon/Protein interfaces Inorganic Chemistry nanostructured biomaterials

Nanomaterial formulation Lanthanide and Actinide Nanomedicine Nanoparticles and characterization Chemistry

Nanostructure Magnetic nanomaterials

Nanotechnology functionalization (chemical)

Nanostructures, particles and Nanocomposites chemistry Carbon nanotubes and nanofibers

Nanoelectronics

Nanostructures

Nanoparticle superlattices

Plasmonics and Quantum Engineered nano effects Quantum dots Plasmonics Dots

Low-power custom- Microelectronics and MEMS Asynchronous Digital Nanoelectronics Nanoimprint lithography integrated nano electronic Packaging Circuits systems Nanoelectronics Carbon based transistors Micro- and nano-scale sensors and interconnects for Electrodeposition and electronics computing hardware

Nanoparticle pattern formation Device fabrication, Plasma Device Fabrication Processes Plasmonics Nanobitechnology Nanoparticles and polymer Smart materials Low Temperature Plasma in magnetized plasmas synthesis of nanomaterials and Diagnostics HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Laboratory Plasma Experiments Material Science / Engineering Material Science / Engineering Material Science / Engineering Gas Discharge Probe Development

Probe Development Chemistry Gas Discharges Chemistry Optical plasma diagnostics Plasma physics Experimental Plasma Science

Fusion energy research Gas Discharges Probe diagnostics Plasma switches

Optical Plasma Diagnostics Space weather

Plasma Probe Engineering Bioscience / Bioengineering Propulsion

Engineering of Optical Plasma Aerospace Engineering Diagnostic Systems

Biomedical

Space Plasma Space Plasma Space Plasma Space Plasma Theory / Computation /

Modeling Atomic Physics Material Science / Engineering Basic Plasma Science

Chemistry

Education / Human Resources Human Development Human Development Human Development Human Development

Nanoparticle Pattern Microwave Plasma Synthesis Plasmas for Food and LTP for vascular graft Plasma Induced Nanoparticle Plasmas for Surface Seed Treatment and Food Plasma Related Combustion Plasmonics Formation in Magnetized and Processing of Superhard Agriculture development and Polymer Synthesis Chemistry Processing Applications for Micro-Thrusters Plasmas Materials

Plasma as a biocide for Plasma Engineering of Nanoparticle Based Cancer Plasma Based Smart Plasma Induced Chemical Plasma Based Nanodevice treating seed and food- Plasma Erosion of Surfaces Plasma Surface Interactions Surfaces for Manufacturing Treatment Materials Reactions Fabrication and Diagnostics borne diseases Plasma Sciences Plasma

Olasma Induced seed Plasma Surface Treatments germination and early Atomic Proceses at Plasma- Plasma Surface Treatment for Plasma Surface Deposition Plasma Based Cancer and Surface Ablation for Plasma Biology and Medicine sprouting in rhizomatous Surface Interfaces Nanoparticles and Polymers for Advanced Manufacturing Treatment Advanced Manufacturing crops.

Plasmas for Nano and Plasma Surface Treatments Promote plant growth, yield Plasma Surface Treatment for Plasma Related Satellite Plasmas for Small Satellite Microparticle Formation and for Advanced Materials and and quality Metals, Alloys, Metal Oxides Propulsion and Systems Propulsion Control in Manufacturing Advanced Manufacturing

Plasma activated water with Plasma Science for High Speed Plasma Surface Treatments Plasmas for Electric soluble nitrogen as a liquid Imaging and Image Processing for Manufacturing Propulsion fertilizer

Applications of Plasma Science Plasma of Applications Plasma and Atomic Science for High Performance Computing

Energy Related Thermal Properties of Plasmas

Plasma as a biocide for sanitizing poultry egg surface HudsonAlpha AAMU ASU AU TU UA UAB UAH USA SR

Testing of electronic components for harsh environment, CAVE3, Center One of the Top Five Test Bed Vehicle dynamics and DOT Personal Training Intelligent transportation Traffic Engineering Route Optimization for Advanced Vehicle Facilities in the Nation controls Electronics for Extreme Environment

Wireless sensor and bridge Autonomous vehicle Vehicle sensing and re- Test Bed of 85 Radio- weigh in motion (BWIM) Geographic Information Intelligent transportation Intelligent transportation development, guidance and identification applications Instrumented Traffic Signals system for next generation Systems systems (ITS) control and GPS systems infrastructure safety

Infrastructure-to-Vehicle Automatic road sign Communication Test Bed Simulation Transportation systems detection for smart vehicle Research

Test Bed is a Prototype for Traffic Engineering Alabama's DOT State-Wide Public Transport Round-About Design Signal System

Traffic Management Urban Planning Highways and intersections Management Systems Roundabouts (traffic)

Highways Traffic circles Traffic congestion and control Traffic operation

Use of the NCAT test track for Electric battery impedance Heavy Equipment Engine Spacecraft propulsion testing of vehicle and fuel Fuels testing measurement facility Efficiency Combustion systems systems

Hybrid propulsion system for automobile using combination Center for Advanced Vehicle Rotorcraft Vehicle development of electric and internal Technologies combustion and fuel cell.

Vehicle Antennas for a Connected-Vehicle Environment

Materials engineering for Timely and Less Costly transportations sector: Highway structures Roadway Pavement Transportation Engineering Coastal Engineering Composites testing automotive, aerospace, Rehabilitation Techniques defense and marine Transportation Related Transportation Engineering "Behind the meter" energy Planning (transportation General Civil Engineering storage utilizing previously systems) used EV batteries

Repository and Study Center for Data for Crashes, Construction site work zone Roadway Characteristics, Software Safety Critical safety; wrong way driving Transportation Safety Traffic, Driver Credentials, Systems Cybersecurity solutions Emergency Response and Patient Treatment

Transportation Safety Fatigued driving Highway safety Resiliency (transportation systems) Roadway departure accidents

Safety in transportation systems Transportation

Concrete Pavement Friction Asphalt pavement research Bridge Maintenance and Texture

Reinforced Structural Highway structures Infrastructure Resilience Composites

Intelligent transportation Design Prestressed Girders Bridge Wave Load systems

Highway Runoff Treatment and Management

Road Technology Pile Foundation Setup (geotechnical)

Asphalt pavements

Recycled materials (pavements)

Sustainable pavements

Warm mix asphalt

Pavement modelling ! ! ! ! ! ! ! ! !

! ! Chris&Lawson,&Ph.D.& Executive&Director& Tel:!!205.975.5059;[email protected]! ! Charlotte&Nix& Briauna Perryman& Program&Administrator& Program&Coordinator&II& Tel:!! Tel:!205.348.7079;[email protected]! 205.996.7168;! ! [email protected] ! Alabama!EPSCoR! !The!University!of!Alabama!at!Birmingham!! Administration!Building,!Room!770Q!! 701!20th!Street!South! Birmingham,!AL!35294R1152! !Tel:!205.975.5059;!Fax:!205.975.0866!! !!Web:!!www.alepscor.org! !

Alabama EPSCoR State Science and Technology Roadmap (AESSTR) 42 as of 9/3/2019