The Weizmann Institute of Science
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
Science and the Public Interest an Open Letter to President-Elect Trump and the 115Th Congress
Science and the Public Interest An Open Letter to President-Elect Trump and the 115th Congress Scientific knowledge has played a critical role in making the United States a powerful and prosperous nation and improving the health and well-being of Americans and people around the world. From disease outbreaks to climate change to national security to technology innovation, people benefit when our nation’s policies are informed by science unfettered by inappropriate political or corporate influence. To build on this legacy and extend the benefits of science to all people, including Americans who have been left behind, the federal government must support and rely on science as a key input for crafting public policy. Policy makers and the public alike require access to high-quality scientific information to serve the public interest. There are several actions Congress and the Trump administration should take to strengthen the role that science plays in policy making. First, creating a strong and open culture of science begins at the top. Federal agencies should be led by officials with demonstrated track records of respecting science as a critical component of decision making. Further, recognizing that diversity makes science stronger, administration officials should welcome and encourage all scientists regardless of religious background, race, gender, or sexual orientation. Second, Congress and the Trump administration should ensure our nation’s bedrock public health and environmental laws—such as the Clean Air Act and the Endangered Species Act—retain a strong scientific foundation, and that agencies are able to freely collect and draw upon scientific data to effectively carry out statutory responsibilities established by these laws. -
Clima Te Change 2007 – Synthesis Repor T
he Intergovernmental Panel on Climate Change (IPCC) was set up jointly by the World Meteorological Organization and the TUnited Nations Environment Programme to provide an authoritative international statement of scientific understanding of climate change. The IPCC’s periodic assessments of the causes, impacts and possible response strategies to climate change are the most comprehensive and up-to-date reports available on the subject, and form the standard reference for all concerned with climate change in academia, government and industry worldwide. This Synthesis Report is the fourth element of the IPCC Fourth Assessment Report “Climate Change 2007”. Through three working groups, many hundreds of international experts assess climate change in this Report. The three working group contributions are available from Cambridge University Press: Climate Change 2007 – The Physical Science Basis Contribution of Working Group I to the Fourth Assessment Report of the IPCC (ISBN 978 0521 88009-1 Hardback; 978 0521 70596-7 Paperback) Climate Change 2007 – Impacts, Adaptation and Vulnerability Contribution of Working Group II to the Fourth Assessment Report of the IPCC (978 0521 88010-7 Hardback; 978 0521 70597-4 Paperback) Climate Change 2007 – Mitigation of Climate Change CHANGE 2007 – SYNTHESIS REPORT CLIMATE Contribution of Working Group III to the Fourth Assessment Report of the IPCC (978 0521 88011-4 Hardback; 978 0521 70598-1 Paperback) Climate Change 2007 – Synthesis Report is based on the assessment carried out by the three Working Groups -
Annual Report 2018
ANNUAL REPORT 2018 JULY 1, 2017 – JUNE 30, 2018 be out-of-date or reflect the bias and expeditionary initiative, which traveled to SCIENCE stereotypes of past eras, the Museum is Transylvania under Macaulay Curator in endeavoring to address these. Thus, new the Division of Paleontology Mark Norell to 4 interpretation was developed for the “Old study dinosaurs and pterosaurs. The Richard New York” diorama. Similarly, at the request Gilder Graduate School conferred Ph.D. and EDUCATION of Mayor de Blasio’s Commission on Statues Masters of Arts in Teaching degrees, as well 10 and Monuments, the Museum is currently as honorary doctorates on exobiologist developing new interpretive content for the Andrew Knoll and philanthropists David S. EXHIBITION City-owned Theodore Roosevelt statue on and Ruth L. Gottesman. Visitors continued to 12 the Central Park West plaza. flock to the Museum to enjoy the Mummies, Our Senses, and Unseen Oceans exhibitions. Our second big event in fall 2017 was the REPORT OF THE The Gottesman Hall of Planet Earth received CHIEF FINANCIAL announcement of the complete renovation important updates, including a magnificent OFFICER of the long-beloved Gems and Minerals new Climate Change interactive wall. And 14 Halls. The newly named Allison and Roberto farther afield, in Columbus, Ohio, COSI Mignone Halls of Gems and Minerals will opened the new AMNH Dinosaur Gallery, the FINANCIAL showcase the Museum’s dazzling collections first Museum gallery outside of New York STATEMENTS and present the science of our Earth in new City, in an important new partnership. 16 and exciting ways. The Halls will also provide an important physical link to the Gilder All of this is testament to the public’s hunger BOARD OF Center for Science, Education, and Innovation for the kind of science and education the TRUSTEES when that new facility is completed, vastly Museum does, and the critical importance of 18 improving circulation and creating a more the Museum’s role as a trusted guide to the coherent and enjoyable experience, both science-based issues of our time. -
No Haven for the Oppressed
No Haven for the Oppressed NO HAVEN for the Oppressed United States Policy Toward Jewish Refugees, 1938-1945 by Saul S. Friedman YOUNGSTOWN STATE UNIVERSITY Wayne State University Press Detroit 1973 Copyright © 1973 by Wayne State University Press, Detroit, Michigan 48202. All material in this work, except as identified below, is licensed under a Creative Commons Attribution-NonCommercial 3.0 United States License. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc/3.0/us/. Excerpts from Arthur Miller’s Incident at Vichy formerly copyrighted © 1964 to Penguin Publishing Group now copyrighted to Penguin Random House. All material not licensed under a Creative Commons license is all rights reserved. Permission must be obtained from the copyright owner to use this material. Published simultaneously in Canada by the Copp Clark Publishing Company 517 Wellington Street, West Toronto 2B, Canada. Library of Congress Cataloging in Publication Data Friedman, Saul S 1937– No haven for the oppressed. Originally presented as the author’s thesis, Ohio State University. Includes bibliographical references. 1. Refugees, Jewish. 2. Holocaust, Jewish (1939–1945) 3. United States— Emigration and immigration. 4. Jews in the United States—Political and social conditions. I. Title. D810.J4F75 1973 940.53’159 72-2271 ISBN 978-0-8143-4373-9 (paperback); 978-0-8143-4374-6 (ebook) Publication of this book was assisted by the American Council of Learned Societies under a grant from the Andrew W. Mellon Foundation. The publication of this volume in a freely accessible digital format has been made possible by a major grant from the National Endowment for the Humanities and the Mellon Foundation through their Humanities Open Book Program. -
Gain-Of-Function Effects of Mutant P53 Explored Using a Three
Gain-of-Function Effects of Mutant p53 Explored Using a Three- Dimensional Culture Model of Breast Cancer William A. Freed-Pastor Submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy under the Executive Committee of the Graduate School of Arts and Sciences COLUMBIA UNIVERSITY 2012 © 2011 William A. Freed-Pastor All Rights Reserved ABSTRACT Gain-of-Function Effects of Mutant p53 Explored Using a Three-Dimensional Culture Model of Breast Cancer William A. Freed-Pastor p53 is the most frequent target for mutation in human tumors and mutation at this locus is a common and early event in breast carcinogenesis. Breast tumors with mutated p53 often contain abundant levels of this mutant protein, which has been postulated to actively contribute to tumorigenesis by acquiring pro-oncogenic (“gain- of-function”) properties. To elucidate how mutant p53 might contribute to mammary carcinogenesis, we employed a three-dimensional (3D) culture model of breast cancer. When placed in a laminin-rich extracellular matrix, non-malignant mammary epithelial cells form structures highly reminiscent for many aspects of acinar structures found in vivo. On the other hand, breast cancer cells, when placed in the same environment, form highly disorganized and sometimes invasive structures. Modulation of critical oncogenic signaling pathways has been shown to phenotypically revert breast cancer cells to a more acinar-like morphology. We examined the role of mutant p53 in this context by generating stable, regulatable p53 shRNA derivatives of mammary carcinoma cell lines to deplete endogenous mutant p53. We demonstrated that, depending on the cellular context, mutant p53 depletion is sufficient to significantly reduce invasion or in some cases actually induce a phenotypic reversion to more acinar-like structures in breast cancer cells grown in 3D culture. -
Susan Solomon National Oceanic and Atmosphere Administration, USA
One Hundred Reasons to be a Scientist SCIENCE OFFERS AN IMPORTANT INPUT Susan Solomon National Oceanic and Atmosphere Administration, USA I began life in Chicago, and first got hooked on science watching the undersea adventures of Jacques Cousteau on TV. In high school, my confidence that science was the right choice for me was boosted when I was lucky enough to take third place in a nationwide science fair with a project that measured the amount of oxygen in gas mixtures. While in undergraduate school studying chemistry at the Illinois Institute of Technology in Chicago, I was fascinated to learn of work being done regarding the chemistry of the atmosphere of the planet Jupiter. That’s what started me on the path to doing chemistry on a planet instead of in a test tube. After graduating from IIT I went to © Courtesy of Carlye Calvin graduate school in chemistry at the University of California at Berkeley. My doctoral dissertation was about chemistry on a planet—not Jupiter but on Earth. I earned my doctorate in chemistry in 1981. Prior to the discovery of the ozone hole, my work focused on what you might call some esoteric aspects of understanding the atmosphere. I was looking at things like the impact of natural factors including the aurora on the chemistry of the mesosphere, thermosphere, and stratosphere. Then the ozone hole was discovered, and that changed everything. I was intrigued by the observation, and one of the first things I thought about, coming from this mesosphere/thermosphere kind of work, was whether reactive nitrogen from phenomena like solar protons could be responsible. -
Calendario De Mujeres Científicas Y Maestras
Mil Jardines Ciencia y Tecnología Calendario de Mujeres Científicas y Maestras Hipatia [Jules Maurice Gaspard (1862–1919)] Por Antonio Clemente Colino Pérez [Contacto: [email protected]] CIENCIA Y TECNOLOGÍA Mil Jardines . - Calendario de Mujeres Científicas y Maestras - . 1 – ENERO Marie-Louise Lachapelle (Francia, 1769-1821), jefe de obstetricia en el Hôtel-Dieu de París, el hospital más antiguo de París. Publicó libros sobre la anatomía de la mujer, ginecología y obstetricia. Contraria al uso de fórceps, escribió Pratique des accouchements, y promovió los partos naturales. https://translate.google.es/translate?hl=es&sl=ca&u=https://ca.wikipedia.org/wiki/Marie-Louise_Lachapelle&prev=search Jane Haldiman Marcet (Londres, 1769-1858), divulgadora científica que escribió sobre química, enero 1 botánica, religión, economía y gramática. Publicó Conversations on Chemistry, con seudónimo masculino en 1805, pero no fue descubierta su autoría hasta 1837. https://lacienciaseacercaalcole.wordpress.com/2017/01/23/chicas-de-calendario-enero-primera-parte/ https://mujeresconciencia.com/2015/08/19/michael-faraday-y-jane-marcet-la-asimov-del-xix/ Montserrat Soliva Torrentó (Lérida, 1943-2019), doctora en ciencias químicas. https://es.wikipedia.org/wiki/Montserrat_Soliva_Torrent%C3%B3 Florence Lawrence (Canadá, 1886-1938), actriz del cine mudo apasionada por los coches, que inventó el intermitente, pero no lo consideró como propio y pasó el final de sus días sola y arruinada. https://www.motorpasion.com/espaciotoyota/el-dia-que-una-mujer-invento-el-intermitente-y-la-luz-de-freno-para-acabar-despues- arruinada Tewhida Ben Sheikh (Túnez, 1909-2010), primera mujer musulmana en convertirse en medica y llegó a plantear temas como la planificación familiar, la anticoncepción y el aborto en su época, en el norte enero 2 de Africa. -
David Rittenberg 1906–1970
NATIONAL ACADEMY OF SCIENCES DAVID RITTENBERG 1906–1970 A Biographical Memoir by DAVID SHEMIN AND RONALD BENTLEY Any opinions expressed in this memoir are those of the authors and do not necessarily reflect the views of the National Academy of Sciences. Biographical Memoirs, VOLUME 80 PUBLISHED 2001 BY THE NATIONAL ACADEMY PRESS WASHINGTON, D.C. Courtesy of Dr. Ronald Bentley DAVID RITTENBERG November 11, 1906–January 24, 1970 BY DAVID SHEMIN AND RONALD BENTLEY AVID RITTENBERG WAS a leader in the development of the D isotopic tracer technique for the study of biochemical reactions in intermediary metabolism. In a brief but his- toric paper published in Science in 1935, Rittenberg and Rudolph Schoenheimer described work at the Department of Biochemistry at Columbia University’s College of Physicians and Surgeons. Their pioneering experiments used deuterium, 2H, the heavy, stable isotope of hydrogen, to trace the fate of various compounds in the animal body. The metabolites containing 2H had properties essentially indistinguishable from their natural analogs by the methods commonly used. Nevertheless, the presence of the isotope made it possible to trace their metabolic fate. Thus, if a 2H-containing com- pound, B, was isolated after feeding the 2H-labeled com- pound, A, to an animal, the metabolic conversion A → B was established. Prophetically, these authors noted that “the number of possible applications of this method appears to be almost unlimited.” Subsequent developments have shown that they were true prophets. In the mid-1930s little was known about the chemical reactions used by living systems to synthesize and degrade cellular components. One difficulty was that methods for the isolation and purification of carbohydrates, lipids, and 3 4 BIOGRAPHICAL MEMOIRS proteins were primitive and methods for the detailed study of enzymes were lacking. -
Recognition of Achievement Not Been Conducted and Here We Suggest It As a Discipline For
Materials Today Volume 00, Number 00 September 2016 COMMENT Comment working in the science and engineering of ceramics and glass has Recognition of achievement not been conducted and here we suggest it as a discipline for consideration as a model for study. Ceramics and glass, a sub-unit – priorities and process of materials science and engineering, encompasses (oxides, 1,2,* nitrides, borides, carbides, inorganic carbon) both traditional Lynnette D. Madsen 1 and new materials. A study of 100 women of achievement in this Svedberg Science, Inc., United States 2 discipline has just been published [2] and this group offers a useful National Science Foundation, United States model for recognition of achievement for organizations in general. [email protected] Election to the National Academies ‘‘is considered one of the 1,2 highest professional honors . new members are elected by cur- Rita R. Colwell rent members based on outstanding achievement and commit- 1 University of Maryland, College Park, United States ment to service’’ [3]. Inherent to the process is nomination by an 2 Johns Hopkins Bloomberg School of Public Health, United States academy member, to be recognized for achievement and subse- quent election by the membership. Election to foreign associate is also important, since foreign associates comprise approximately A closer look at the national 10% of membership in the Academies and foreign women can be academies (and have been) elected as associates. Unlike a nomination for the Nobel Prize [4], nomination for membership in the US National Academies is made by US academy members. Honorary membership organizations strive to recognize excel- Thirteen outstanding women having significant accomplish- lence in performance and achievement. -
The Interuniversity Institute for Marine Sciences in Eilat Most Active Non-Resident Researchers
The Interuniversity Institute for Marine Sciences in Eilat Most Active Non-Resident Researchers Short CVs and lists of 5 significant recent publications Abelson, Avigdor – Tel Aviv U. Lazar, Boaz –Hebrew U. Abramovich, Sigal – Ben Gurion U. Levy, Oren – Bar Ilan U. Addadi, Lia – Weizmann Inst. Lindell, Debbie – Technion Agnon, Amotz –Hebrew Univ. Lotan, Tamar – U. Haifa Beja, Oded – Technion Loya, Yossi – Tel Aviv U. Belmaker, Jonathan – Tel Aviv U. Mass, Tali – U. Haifa Benayahu, Yehuda – Tel Aviv U. Oren, Aharon – Hebrew U. Berman-Frank, Ilana – Bar Ilan U. Shashar, Nadav – Ben Gurion U. Dubinsky, Zvy – Bar Ilan U. Shavit, Uri – Technion Erez, Jonathan – Hebrew U. Shemesh, Aldo –Weizmann Inst. Gildor, Hezi – Hebrew U. Shenkar, Noa – Tel Aviv U. Goodman-Tchernov, Beverly – U. Haifa Sher, Daniel – Haifa U. Ilan, Micha – Tel Aviv U. Tchernov, Dan – U. Haifa Iluz, David – Bar Ilan U. Treibitz, Tali – U. Haifa Keren, Nir –Hebrew Univ. Vardi, Assaf - Weizmann Kushmaro, Ariel – Ben Gurion U. Weiner, Steve –Weizmann Inst. Prof. Abelson, Avigdor (Back to top of document) Affiliation: Dept. of Zoology, Faculty of Life Sciences, Tel Aviv University Tel. No: 972-3-6407690; 972-3-6406936; 972-54-6967555 Email: [email protected] URL: https://en-lifesci.tau.ac.il/profile/avigdor Academic Degrees: 1981-1984 B.Sc. The Hebrew University of Jerusalem, Israel 1985-1987 M.Sc. Tel Aviv University, Israel 1987-1993 Ph.D. Tel Aviv University, Israel 1993-1995 Post-doctoral fellow Stanford University, USA Academic Positions: 2007-present Associate Professor Dept. of Zoology, Tel Aviv University 1999-2007 Senior Lecturer Dept. of Zoology, Tel Aviv University 1995-1999 Lecturer Institute of Nature Conservation, Tel Aviv University Selected Awards: 1989 Mifal-Hapais - Landau Award for Graduate Students 1989 The Zoological Society of Israel - Blondheim Prize for the best M.Sc. -
CHEMICAL HERITAGE FOUNDATION JEROME A. BERSON Transcript Of
CHEMICAL HERITAGE FOUNDATION JEROME A. BERSON Transcript of an Interview Conducted by Leon Gortler at New Haven, Connecticut on 21 March 2001 (With Subsequent Corrections and Additions) Upon Jerome Berson’s death in 2017, this oral history was designated Free Access. Please note: Users citing this interview for purposes of publication are obliged under the terms of the Chemical Heritage Foundation (CHF) Center for Oral History to credit CHF using the format below: Jerome A. Berson, interview by Leon Gortler at New Haven, Connecticut, 21 March 2001 (Philadelphia: Chemical Heritage Foundation, Oral History Transcript # 0196). Chemical Heritage Foundation Center for Oral History 315 Chestnut Street Philadelphia, Pennsylvania 19106 The Chemical Heritage Foundation (CHF) serves the community of the chemical and molecular sciences, and the wider public, by treasuring the past, educating the present, and inspiring the future. CHF maintains a world-class collection of materials that document the history and heritage of the chemical and molecular sciences, technologies, and industries; encourages research in CHF collections; and carries out a program of outreach and interpretation in order to advance an understanding of the role of the chemical and molecular sciences, technologies, and industries in shaping society. JEROME A. BERSON 1924 Born in Sanford, Florida, on 10 May Education 1944 B.S., chemistry, City College of New York 1947 A.M., chemistry, Columbia University 1949 Ph.D., chemistry, Columbia University Professional Experience 1944 Hoffmann-La Roche 1944-1946 U.S. Army University of Southern California 1950-1953 Assistant Professor 1953-1958 Associate Professor 1958-1963 Professor 1963-1969 University of Wisconsin, Professor Yale University 1969-1979 Professor 1979-1992 Irénée du Pont Professor 1992-1994 Sterling Professor 1994-present Sterling Professor Emeritus of Chemistry and Senior Research Scientist Honors 1949 National Research Council Postdoctoral Fellowship, Harvard University (R.B. -
THE AMERICAN JOURNAL of CANCER a Continuation of the Journal of Cancer Research
THE AMERICAN JOURNAL OF CANCER A Continuation of The Journal of Cancer Research - - VOLUMEXXX AUGUST,1937 NUMBER4 THE TRANSMISSIBLE AGENT OF THE ROUS CHICKEN SARCOhIA NO. 1 JAMES W. JOBLING, M.D., E. E. SPROUL, M.D., AND SUE STEVENS, M.A. (From the Department of Patlzology, College of Physicians and Surgeons, Columbia University) That animal tumors can be successfully transmitted within the species has been known for many years. The process was easily understood so long as living cells were required for transmission, the growth presumably resulting from continued division of the viable tumor cells. The discovery by Rous in 19 11 ( 1) that a chicken sarcoma could be produced in normal fowl by in- jection of a cell-free extract of the tumor considerably altered the general point of view, but at the same time offered the hope that the nature of the responsible agent would eventually be established. The hypotheses which have stimulated widely varying experimentation may be roughly divided into those regarding the agent as of extrinsic origin and those seeking its source in the metabolic processes of the host itself. Interpretation of the development of the Rous sarcoma as the result of infection with a living parasite, a virus more related to the causative agent of chicken pox, vaccinia, herpes, etc., is supported chiefly by analogy. An- drewes (2) has been most impressed by the properties borne in common by the Rous sarcoma and the more readily accepted virus infections. Nor does he accept the variation in type of response as a serious discrepancy, since he shows that the viruses can stimulate hyperplasia as well as necrosis and that all gradations between the two can be found.