Peter Carmeliet

CURRICULUM VITAE

Gender: male Place and date of birth: Leuven, December 8, 1959 Married to: Baes Myriam, November 11, 1958 Children: Tine, born February 16, 1990 Dries, born October 13, 1991 Reinout, born February 7, 1993 Address: Sappellenbos 10, B-3052 Blanden (+32-16-40.28.86) Office: Vesalius Research Center Vlaams Instituut voor Biotechnologie (VIB) University of Leuven (KULeuven) Campus Gasthuisberg, Herestraat 49 – B912 B-3000 Leuven, Belgium (Tel: +32-16-34.57.74; Telefax: +32-16-34.59.90) e-mail:[email protected]

Education 1984 Doctor in Medicine (M.D.), K. U. Leuven, Belgium (Maxima cum laude) 1989 Ph.D.; Aggregation "Higher Education in Medicine", K.U. Leuven, Belgium

Residencies and Research Fellowships 1978 Visiting research scientist, University of Maryland, Baltimore, USA 1981 Visiting research scientist, UCSF, San Francisco, USA 1984-1986 Resident Internal Medicine, University Hospital Leuven, Belgium 1986 Grass Fellow Marine Biological Laboratories, Woods Hole, MA, USA 1987 Visiting research scientist, University of Maryland, Baltimore, USA 1989-1990 Postdoctoral training (NATO Research Fellow, D. Collen Research Foundation Fellow), Harvard Medical School, Boston, MA, USA 1990-1992 Postdoctoral training (D. Collen Research Fellow); Whitehead Institute, MIT, Cambridge, MA, USA

Academic Appointments 1985-1989 Aspirant “National Fund for Scientific Research of Belgium” (NFWO) 1990-1994 Research Associate “National Fund for Scientific Research of Belgium” (Aangesteld Navorser, NFWO) 1993-1995 Lecturer in "Master & Ph.D. Program in Medical and Pharmaceutical Research", Free University of Brussels 1993-1996 Member of the Bureau of the Department of Molecular and Cardiovascular Biology, Faculty of Medicine, University of Leuven 1994-1998 Associate Professor (Hoofddocent), Faculty of Medicine, University of Leuven, Belgium 1994-1996 Adjunct Staff, Cleveland Clinic Foundation, USA 1995-1997 Visiting Professor, Free University of Brussels 1996-2008 Adjunct-Director, Center Transgene Technology & Gene Therapy, Flanders Interuniversity Institute for Biotechnology, University of Leuven, Belgium. 1996- Ph.D. thesis committee, Faculty of Medicine, University of Leuven, Belgium 1996-1997 Student-Researcher committee, Faculty of Medicine, University of Leuven, Belgium 1998-2000 Professor (Hoogleraar), Faculty of Medicine, University of Leuven, Belgium 1999- Professor, Cardiovascular Research Institute Maastricht, Maastricht, The

1 Peter Carmeliet

Netherlands 2000- Full Professor (Gewoon Hoogleraar), Faculty of Medicine, University of Leuven, Belgium 2004- Visiting Professor, Darthmouth University, NH, USA 2008- Director, Vesalius Research Center, Vlaams Instituut voor Biotechnologie, VIB

Teaching 1992- Interdisciplinary Seminars in Medicine (Gene targeting & gene transfer) (0.3 year.hr; 3rd year Medical School, University of Leuven, Belgium) 1993-1997 Seminars in Medical and Pharmaceutical Research (Gene targeting & gene transfer) (0.25 year.hr, University of Brussels) 1993- Biotechnology in Medical Science (0.25 year.hr; 5th year Agricultural Engineering, KU Leuven) 1994- Theoretical and Applied aspects of Gene Therapy (1.0 year.hr; 3rd and 7th year Medical School, University of Leuven, Belgium) Seminars in Cell- and Gene Biotechnology (0.25 year.hr; 3rd year Bioengineers in Cell- and Gene Biotechnology, University of Leuven, Belgium). 2001- Harvard Medical School, Boston, Massachusetts, USA (Course on Angiogenesis).

Awards and Honors 1984 Award of the Belgian Society for Cardiology, Belgium 1990 R. Stock Prize, University of Leuven, Belgium 1994 G. Zambon Prize, Group Zambon, Belgium 1994 Award of the Restenosis Summit VI, Cleveland Clinic Foundation, OH, USA 1995 Marion Barnhart Memorial Award, XVth Congress, Intl Society of Thrombosis and Hemostasis, Jerusalem, Israel 1996 Annual Owren Lecture on Hemostasis, The Norwegian Academy of Science and Letters, Oslo, Norway Medal of the British Society of Hematology, Birmingham, U.K. 1998 Biannual Prize of the International Society of Fibrinolysis Triannual Prize of Smith-Kline Beecham (Royal Academy of Belgium) 1999 Annual R. Berne Award of Vascular Biology, Univiversity of Virginia, Charlottesville, USA. Bekales Prize for Cardiology Investigation Achievement Award, Intl Society of Thrombosis and Hemostasis Elected Member of the European Molecular Biology Organization (EMBO) 2001 Elected as Fellow of the American Heart Association 2002 Nobel Forum Lecture (invited by Nobel Committee & Karolinska Institute) Elected Member, American Society of Clinical Investigation Harvey’s Centennial Celebration Lecture, Padova, Italy E.Giles Award, Calgary, Canada Outstanding Investigator Award, International Society of Heart Research Francqui Prize 2002, Belgian Academy Medicine (co-founder H. Hoover; 150,000€) Bristol Myers Squibb Unrestricted Grant ($500,000) Liliane Bettencourt Life Sciences Award 2002 (€250,000) 2003 George Brown Lecture and Plenary Lecture (Am Heart Assoc Meeting; Chicago) Marion Barnhardt Award, Intl Society Thromb Hemost (Birmingham, 2003) Perspectives in Molecular Medicine Lecture (Goethe University Frankfurt, Germany) Ernst Schering Lecture, Berlin, Germany 2004 Benditt Award, North American Vascular Biology Organization, Toronto, Canada Elected as Fellow of the Intl Society Heart Research Elected as Fellow of the Intl Society of Clinical and Applied Thrombosis and Hemostasis Einthoven lecture, Weinstein Symposium, Netherlands 2005 Interbrew-Baillet Latour Prize, 2005, Belgium (jointly with Désiré Collen; €200,000).

2 Peter Carmeliet

ICRH Distinguished Lecture and Prize in Cardiovascular Sciences, Institute of Circulatory and Respiratory Health, Vancouver, Canada 2006 Feodor Lynen Lecture, Nature Biotechnology Winter Symposium, Miami, USA Sheila Essay Award, American Academy of Neurology, San Diego, USA ($25,000) Presidential Special Lecture, Society of Neuroscience Annual meeting, Atlanta, USA Holst Memorial Award, University of Eindhoven, Netherlands Francqui Leerstoel, University of Liege, Belgium 2007 Lucian Award for research in Circulatory Disease, McGill University, Canada ($50,000) European Society Cardiology William Harvey Lecture on Basic Science, ESC meeting, Vienna, Austria Francqui Leerstoel, University of Brussels, Belgium Roger Guillemin Nobel Lecture, Salk Institute, La Jolla, USA Ariens Lecture, Dutch Society of Pharmacology, Lunteren, The Netherlands 2008 Francqui Leerstoel, Université Catholique de Louvain, Brussels, Belgium

Membership in Professional Societies 1993- International Society on Thrombosis and Haemostasis 1994- International Society of Fibrinolysis 1996- Council of the European Vascular Biology Association (invited member) 1997- North American Vascular Biology Association 1998 Council Member, Intl Society Thrombosis and Hemostasis, Class 2004 (by election) 1998- Secretary of the European Vascular Biology Association

Editorial tasks − Editorial Board: Science (from mid 2005), Cancer Cell (from 2004), Journal of Clinical Investigation (from 2005), Circulation Research (2004), Atherosclerosis Thrombosis and Vascular Biology, European Heart Journal (2004) − Nature Reviews Cancer (Angiogenesis Highlights Advisor)(2002-2004) − Guest Editor of the Special Volume on Gene Transfer (Cardiovascular Research), Seminars in Cell & Developmental Biology (special seminar on "Angiogenesis"). − Solicited reviewer for: Nature, Nature Medicine, Nature Genetics, Nature Cell Biology, Nature Neuroscience, Nature Biotechnology, Science, Cell, Developmental Cell, Molecular Cell, Genes Development, Journal of Clinical Investigation, New England Journal of Medicine, Proceedings National Academy of Sciences USA, Journal of Cell Biology, Circulation, Circulation Research, Annals of Neurology, Development, Developmental Biology, Blood, Journal of Biochemistry, PloS, American Journal of Human Genetics, Journal Neuroscience, Trends in Cardiovascular Medicine, American Journal of Pathology, International Journal of Cancer, Thrombosis Hemostasis, Arteriosclerosis Thrombosis and Vascular Biology, Cardiovascular Research, Journal of Physiological Science, Biophysical Biochemical Acta, Developmental Dynamics, Journal of Vascular Research, Biochemical Pharmacology, European Journal of Physiology, Journal of Neurogenetics. − Solicited reviewer of grants: EMBO, NMRC Australia, Dutch Heart Foundation, Weizmann Institute, European Community Biomed programs, Human Frontiers Science Program, Welcome Trust UK, NATO, Telethon. − Panel Member of the European Research Council (ERC)

Participation in scientific advisory boards & international meetings 1993 Scientific Program Committee, XIIth Intl Congress “Fibrinolysis”, Belgium. 1995 Scientific Program Committee, XIIIth Intl Congress “Fibrinolysis”, Barcelona 1996 Scientific Program Committee, VIth Intl Congress, Metastasis Society, Belgium. Scientific Program Committee, IXth Intl Vascular Biology Meeting, Seattle Scientific Advisory Committee, 1st European American Conference, Paris

3 Peter Carmeliet

1997 Scientific Advisory Committee XIXth Meeting European Society Cardiology, Stockholm, Sweden. 1998 Chairman Vth Intl Meeting, European Vascular Biology Association, Belgium Scientific Advisory Board, 70th Europ Atheroscl Assoc Congress, Israel Co-chairman, Scientific Subcommittee on Animal, Cellular, and Molecular Models of Thrombosis 1999 Co-chairman IIGB Intl Meeting “Vasculogenesis & Angiogenesis”, Naples, Italy Chairman Intl Meeting “Angiogenesis”, Eur Society Hematology, Paris, France. Co-organizer 4th FASEB Conference, Vermont, USA. Co-organizer “1st US-European Meeting Mol Basis Cardiovasc Diseases”, Paris Scientific Advisory Committee, VIIth Intl Workshop “Plasminogen Acitivation”, Diablerets, Switzerland. Scientific Advisory Committee, XXth Intl Meeting ISHR, the Netherlands. Scientific Advisory Committee, XVIIth Intl Congress ISTH, Washington USA. Scientific Advisory Board, Max-Planck-Institut für physiologische und klinische Forschung, Bad Nauheim, Germany Co-chairman, Scientific Subcommittee on Animal, Cellular, and Molecular Models of Thrombosis 2000 Chairman Intl Meeting “Angiogenesis”, European Society of Hematology, Paris. Chairman, Subcommittee on Animal, Cellular and Molecular Models of Thrombosis, International Society on Thrombosis and Haemostasis. Co-organizer 19th World Congress Intl Union Angiology, Ghent, Belgium. Co-organizer Intl Congress European Tissue Repair Society, Brussels, Belgium Co-organizer 1st “European Life Scientist Organization” (ELSO), Geneva. Co-organizer 2nd Intl Symp “Cardiovascular physiology of mice”, Amsterdam Scientific Advisory Committee XVth Intl Congress “Fibrinolysis”, Japan. Scientific Advisory Board, Wellcome Trust Centre Human Genetics, Oxford 2001 Chairman Intl Congress “Angiogenesis”, European Society of Hematology, Paris Chairman, Subcommittee on Animal, Cellular and Molecular Models of Thrombosis, International Society on Thrombosis and Haemostasis. Co-chairman ‘Euroconference on Angiogenesis”, Paris, 2001 Member, Scientific Advisory Board, Wellcome Trust Centre Human Genetics, Oxford. 2002 Co-chairman International Keystone Symposium on ‘Angiogenesis”, Banff, Canada Scientific Program Committee XIIth Intl Vascular Biology Meeting, Tokyo 2003 Scientific Advisory Board: Cancer Research Institute, University Lausanne, Switzerland; Wellcome Trust Centre Human Genetics, Oxford, UK. 2005 Scientific Advisory Board: XIV Intl Symposium on Atherosclerosis, Rome, Italy Scientific Evaluation Committee : Centro Nacional de Investigaciones cardiovasculares “Carlos III” (CNIC), Madrid, Spain 2006 Scientific Advisory Board: Centro Nacional de Investigaciones Oncologicas (CNIO) , Madrid, Spain 2008 Co-chairman International Keystone Symposium on “Molecular Mechanisms of Angiogenesis in Development and Disease”, Vancouver, Canada

Research activities Research position Vice-Director; Supervising the “Functional Genomics Group” of more than 65 staff-members (including senior scientists, post-doctoral and pre- doctoral students, laboratory assistants). Research Areas Using genetic and gene-manipulation technologies in mice, zebrafish, Xenopus and humans, we study the molecular basis of: (i) angiogenesis and lymphangiogenesis in health and disease; (ii) cardiovascular disorders including hemostasis, atherosclerosis, myocardial ischemia,

4 Peter Carmeliet

systemic and pulmonary hypertension, arrythmias; (iii) neurodegeneration; in particular the role of VEGF in motor neuron degeneration (ALS). Publications The author's scientific output consists of 368 published research papers, and survey articles in peer-reviewed international journals, and 29 survey chapters in books. 27.796 citations. Updated March 2009

The author’s scientific analysis in the Angiogenesis domain has been highlighted in “The Special Topics site” of the ISI Essential Science Indicators (ESI). www.esi-topics.com/angiogenesis/interviews/PeterCarmeliet.html

An analysis by Science Watch published in Jan-Feb 2006 that Peter Carmeliet ranked on position 8 of the 10 most cited authors in General Biomedicine. Science Watch¨, January/February 2006, Vol. 17, No. 1 Citing URL: http://www.sciencewatch.com/jan-feb2006/sw_jan- feb2006_page1.htm http://scientific.thomson.com/products/esi/

Grants 1994-1999 VLAB/COT-008, Belgium; €1.25 mio 1996-1999 Human Frontiers Science GR 363/95; €0.64 mio 1996-2001 VIB, Belgium; €18 mio 1998-2001 EU Grant BMH4-CT98-3380; €0.75 mio total (coordinator: €0.133 mio) 1998-2000 FWO-7.0019.98 Levenslijn, Belgium, €0.29 mio 1999-2001 FWO Angiogenesis G.0125.00, Belgium; €0.0775 mio 1999-2001 ASLK Cancer, Belgium; €0.15 mio 2000-2004 GOA/KULeuven, Belgium; €1.5 mio 2001-2004 FWO Gas6 G0265-01, Belgium; €0.125 mio 2000-2002 Thromb-X, Belgium (corporate); €0.5 mio 2001-2003 EU grant ‘Angionet’QLRT-2000-0530, €0.56 mio 2001-2003 EU grant ‘Atronet’ QLGI-CT2001-1172, €0.25 mio 2002-2006 VIB, Belgium; €15.75 mio 2002-2005 FWO PlGF G.0121.02, Belgium; €0.15 mio 2002-2005 FWO Neuro G.0113.02, Belgium; €0.275 mio 2001-2007 Interuniversity Attraction Pole; €0.75 mio 2002-2003 Muscle Dystrophy Association; €0.225 mio 2002-2007 Bristol Squibb Myers Research Grant; €0.56 mio 2003-2007 FWO G.0378.03, Belgium; € 0.27 mio 2003-2007 FWO G.0281.03, Belgium; € 0.29 mio 2003-2006 European grant QLRT-2001-01955; € 0.42 mio 2003-2005 Forton Fund for Mucoviscidosis Res., Belgium; € 0.1 mio 2003-2005 AHAF Alzheimer’s Disease Res. Prog., USA; € 0.1 mio 2003-2004 IFP Zurich, Switserland; € 0.075 mio 2004-2005 Association Française contre les Myopathies (AFM), France; € 0.015 mio) 2004-2006 Muscle Dystrophy Association; € 0.363 mio 2004-2007 Philip Morris Research Grant Foundation; € 0,8 mio 2004-2007 FWO G.0265.04, Belgium; € 0.4 mio 2004-2008 European grant 6th Framework; € 1.25 mio 2004-2006 IWT Belgium; € 1.0 mio

5 Peter Carmeliet

2005-2008 Amyotrophic Lateral Sclerosis Association; € 0.175 mio 2005-2008 FWO Lymphangiogenesis G.0567.05, Belgium; € 0.22 mio 2005-2009 GOA/KULeuven, Belgium; €1.5 mio 2005-2006 Charcot Stichting – Belgische Vereniging voor Neurologie, Belgium; € 0,04 mio 2005-2006 Inbev Baillet Latour Prize, Belgium; € 0,025 mio 2006-2008 Littlefield AACR Research grant; $ 0.250 mio 2007-2011 VIB Belgium, € 23 mio 2007-2010 FWO Axon Guidance, Belgium; € 0.375 mio 2007-2011 Interuniversity Attraction Pole; € 0.80 mio 2007-2010 Motor Neuron Disease Organization; £ 0.200 mio 2007-2014 Methusalem – KULeuven, Belgium : € 6,65 mio 2007-2009 IWT, Belgium; € 0,720 mio 2008-2009 GSKE, Belgium; € 0,05 mio 2009-2009 EFSD – Diabetes; 0,010 mio 2009-2011 Susan G. Komen for the Cure – Research Grant; € 0,480 mio 2009-2012 Belgische Stichting tegen Kanker, € 0,320 mio 2009-2012 FWO G.0676.09N VEGF & Neuromuscular Junction, Belgium; € 0,371 mio 2009-2010 FWO G.0567.05N, Lymphangiogenomics Belgium; € 0,195 mio 2009-2012 FWO G.0677.09N, VEGF & Cerebellum development, Belgium; € 0,080 mio 2009-2011 EU FP7 Health – Infarct Cell Therapy; € 0,300 mio updated January 2009

Fellowships 1992-1994 senior scientist (paid by Cleveland Clinic, OH, USA) 1993-1996 senior scientist (paid by Cleveland Clinic, OH, USA) 1994-1996 TMR post-doctoral student; senior scientist (paid by Toronto University, Canada) 1996-2000 3 FWO PhD students; 1 IWT PhD student 1997-1998 1 post-doctoral student (paid by Tokyo University, Japan) 1997-1999 TMR post-doctoral student; 2 PhD students (paid by Notre Dame University, USA); senior scientist (paid by University of Amsterdam, NL) 1997-2001 1 FWO PhD student; 1 IWT PhD student; 1 PhD student (Thromb-X) 1998-2000 Swiss National Science Foundation post-doctoral student 1998-2002 1 FWO PhD student 1999-2003 1 IWT PhD student 2000-2004 1 IWT PhD student 2000-2004 1 FWO PhD student, 1 EMBO long term fellowship 2001-2003 1 FWO post-doctoral student 2001-2005 2 IWT PhD students 2001-2005 1 FWO PhD student 2002-2005 3 post-doctoral fellows 2003-2005 1 NIH postdoctoral fellow 2003-2005 1 Philip Morris postdoctoral fellow 2003-2005 1 EU Marie Curie postdoctoral fellow 2003-2005 1 CNIC postdoctoral fellow 2003-2005 1 BAEF postdoctoral fellow 2003-2007 1 IWT PhD student 2004-2005 1 ARS postdoctoral fellow 2004-2007 1 CNIC postdoctoral fellow 2004-2005 2 GRF postdoctoral fellow 2004-2005 1 AFM fellowship 2004-2005 2 Ministerio de Educación y Cïencia – Spain postdoctoral fellows 2005-2007 1 EU Marie Curie postdoctoral fellow 2005-2007 1 Shering postdoctoral fellow 2005-2007 1 EMBO long term fellow

6 Peter Carmeliet

2006-2010 4 IWT PhD students 2006-2007 1 Lymphatic Research Foundation postdoctoral fellow 2006-2007 1 EU Marie Curie postdoctoral fellow 2006-2007 1 BOF postdoctoral fellow 2006-2008 1 EMBO postdoctoral fellow 2007-2009 1 EMBO postdoctoral fellow 2007-2009 1 DKH postdoctoral fellow 2008-2010 1 DFG postdoctoral fellow 2008-2010 1 EU Marie Curie postdoctoral fellow 2008-2012 2 IWT PhD students 2007-2011 3 EMBL PhD students 2008-2012 2 PhD students 2008-2010 1 HFSP postdoctoral fellow 2008-2010 1 postdoctoral fellow funded by Nara University - Japan 2009-2011 1 EU Marie Curie postdoctoral fellow 1994-now more than 50 pre- or postdoctoral students have worked in our Center for between 1 to 6 months (own funds) updated January 2009

Patent Applications

Application nr Description Inventor(s) Ownership GB 0002527.0 Vascular endothelial growth Carmeliet P., Collen D. DCRF, VIB factor (VEGF), placenta growth factor (PlGF) or both for preventing or treating ischemic diseases or stroke. EP 00201325.8 Use of VEGF and homologues to Carmeliet P., Collen D., VIB, DCRF treat neuron disorders Oosthuyse B. GB 0009321.1 Use of inhibition of a GAS6 Carmeliet P., Collen D., VIB, DCRF function or of a GAS6 receptor Angelillo-Scherrer A. for preventing and treating a cardiovascular disease EP 00201714.3 Use of inhibitors of placental Carmeliet P., Collen D., VIB, DCRF growth factor for the treatment of De Falco S., Menotti R. pathological angiogenesis, pathological arteriogenesis, inflammation, tumour formation and/or vascular leakage

EP 00202228.3 Use of urokinase inhibitors for the Carmeliet P., Collen D., VIB, DCRF treatment and/or prevention of Heymans S., Levi M. pulmonary hypertension and/or cardiac remodelling

7 Peter Carmeliet

EP 01201481.7 Use of hypoxia inducible factor Carmeliet P. & VIB, DCRF 2alpha for curing neonatal Compernolle V. respiratory distress syndrome and as a target for the treatment of pulmonary hypertension US 60/299,610 Method of treating Carmeliet P., Hicklin D., Imclone Systems atherosclerosis Liao F., Luttun A. & Wu Incorporated, VIB Y. US 60/299,192 Stimulation of vascularization Eriksson U., Li X., Ludwig Institute for with VEGF-B Carmeliet P., Collen D. cancer research, VIB EP 01204998.7 Use of urokinase receptor Carmeliet P., Collen D., VIB, DCRF antagonists to modulate Theilmeier G. & Van ischemia-reperfusion injury Aken H. GB 0201983.4 Tissue adhesion formation Koninckx Ph., Carmeliet LRD, VIB, control P., Collen D., Molinas S., Thromb-x Carlos R. EP 02075544.3 AC133, a novel target to inhibit Carmeliet P., Moons L. VIB, DCRF angiogenesis EP 02077591.2 Placental growth factor as a Carmeliet P., Collen D., VIB, DCRF, LRD target for the treatment of Bouillon R., Carmeliet G. osteoporosis US 10/303.997 Composition and method for Li X., Eriksson U., Ludwig Institute for modulating vasculogenesis or Carmeliet P., Collen D. Cancer Research, angiogenesis VIB US 60/445.021 VEGF-B and PDGF modulation Alitalo K., Eriksson U., Ludwig Institute for of stem cells Ylä-Herttuala S. Salven Cancer Research, P., Rajantie I., Carmeliet VIB P., Collen D. EP 03103675.9 Means and methods for the Carmeliet P., Twja M. DCRF recruitment of stem cells EP1517704 Use of antibodies against FLT-1 Carmeliet P., Collen D., VIB, LRD, DCRF for the treatment of osteoporosis Carmeliet G., Bouillon R. WO 2005007183 Treatment of anemia Angelillo-Sherer A., Thromb-X Carmeliet P., Collen, D. EP 03104123.9 Transgenic amphibian models for Carmeliet P. VIB, DCRF lymphatic vessel development EP 04102334.2 Treatment of amyotrophic lateral Carmeliet P. VIB, DCRF sclerosis EP 05105923.6 Treatment of liver cirrhosis and Carmeliet P. VIB, DCRF, UGent its complications Colle I. Geerts A. EP06100440.4 Inhibitors of Prolyl-hydroxylase 1 Carmeliet P. VIB, LSRP for the treatment of skeletal Aragones J.L. muscle degeneration EP20060120124 Means and methods for the Carmeliet P VIB, LSRP, stimulation of skeletal muscle Minchiotti G. Minchiotti G, regeneration Carmeliet P EP20060117242 Use of PPAR-alpha agonists to Carmeliet P VIB, LSRP, treat skeletal muscle wasting Carmeliet P.

8 Peter Carmeliet

disorders

US20060909604 Novel anti-PlGF antibody Carmeliet P. VIB, DCRF Stassen J.M. Thromb-X Collen D.

Honorary Lectures by Election or Invitation (selected list) 1992 − VIIth International Symposium “Biology of the Vascular Cells”, San Diego, USA. Plenary Lecture

1993 − 37th Annual Meeting Gesellschaft für Thrombose- und Hämostase-Forschung, Austria. Plenary Lecture − 62nd Congress, European Atherosclerosis Society, Israel. − Keystone Symposia “The Molecular Biology of the Endothelial Cell”, USA. Plenary Lecture

1994 − Gordon Research Conference “Proteases and Inhibitors”, N London, New Hampshire, USA − Gordon Research Conference “Vascular Wall Biology”, N London, New Hampshire, USA − Gordon Research Conference “Hemostasis”; Andover, New Hampshire, USA − Gordon Research Conference “Thrombolysis”, Ventura, California, USA. − XIIth Intl Symp “Fibrinolysis & Thrombolysis”, Leuven, Belgium, State of the Art Lecture − VIIIth International Symp “Biology of Vascular Cells”, Germany − Xth Intl Symp “Atherosclerosis”, Canada. Plenary Lecture − Intl Symp Belgian Society Haemostasis and Thrombosis, Belgium.

1995 − 39th Ann Meeting Gesellschaft für Thrombose- und Hämostase-Forschung, Austria. Plenary Lecture − ASIP/FASEB Meeting, Atlanta, USA. − Restenosis Summit VII, Cleveland, USA − XVth Congr International Society of Thrombosis and Hemostasis, Jerusalem, Plenary "Marion Barhart Memorial Lecture": − Gordon Research Conference “Atherosclerosis”, Meriden, New Hampshire, USA − XIIIth meeting of the International Society of Haematology, Istanbul, Turkey. − Australian Vascular Biology Society meeting, Terrigal, Australia. Keynote Address − Tumor Necrosis meeting, Max-Planck-Gesellschaft, Schloss Ringsberg, Germany.

1996 − Symp Dutch Society of Thrombosis and Hemostasis, Houthalen, Belgium. − IVth Saratoga International Conference on “Atherosclerosis”, Hawaii − Gordon Research Conference on “Thrombolysis”, Ventura, USA − VIIIth Research Initiatives “Vascular Disease Conference (NIH)”, Bethesda, USA. − Asian-Pacific Congress “Vascular Disease Prevention”, Singapore. Plenary Lecture − Symposium “Growth factors, mechanical forces and extracellular interactions in the regulation of cardiovascular function”, British Heart Foundation, Oxford, UK − Annual Meeting German Society on Cardiology, Mannheim, Germany.

9 Peter Carmeliet

− Restenosis Summit VIII, The Cleveland Clinic Foundation, Cleveland, OH, USA − 2nd Meeting of the European Haematology Association, Paris, France. − XIIIth Intl Congress “Fibrinolysis and Thrombolysis”, Barcelona, Spain. Plenary Lecture − 66th Congr European Atherosclerosis Society, Florence, Italy. Plenary Lecture − Meeting of the Max-Planck-Gesellschaft, Schloss Ringsberg, Germany. − Gordon Research Conference “Peptide Growth Factors”, New Hampshire, USA. − Sixth World Congress of “Microcirculation”, Munich, Germany − IXth Intl Vascular Biology Meeting, Seattle, Washington, USA. Plenary Lecture − VIth Intl Congress of the Metastasis Research Society, Ghent, Belgium. − Symposium Update on “Thrombolysis”, Heidelberg, Germany. − 3rd Intl Zimmerman Conference: “Progress in Vascular Biology, Thrombosis and Hemostasis”, Hakone, Japan. Plenary Lecture − 14th Intl Congress on “Thrombosis”, Montpellier, France. Plenary Lecture − The Annual Owren Prize Lecture, Oslo, Norway. − 69th American Heart Association Meeting, New Orleans, USA.

1997 − 2nd COE Intl Symp “New Frontiers in Vascular Biology”, Osaka, Plenary lecture − Institut Pasteur Euroconferences, Paris, France − 4th International Symp “Multiple Risk Factors in Cardiovascular Disease”, Washington, USA. Plenary Lecture − 2nd Intl Symp “Cardiovascular Biology and Medicine”, Pamplona, Spain − 68th European Atherosclerosis Society Meeting, Brugge, Belgium. Plenary lecture − International Symposium on the “Biology of Tumors”, Roveroto, Italy. − XVIth Congr Intl Society of Thrombosis and Hemostasis, Florence, Italy − Gordon Research Conference “Atherosclerosis”, Meriden, New Hampshire, USA − 4th Intl Franz Volkhard Symposium “Smooth muscle lineage development”, Berlin, Germany − XXXIIIth International Congress Physiological Sciences, St-Petersburg, Russia. − Gordon Research Conference on “Matrix Metalloproteinases”, New Hampshire, USA. − 3rd FASEB Conference “Thrombin and Vascular Medicine”, Saxton's River, Vermont, USA. − Gordon Research Conference “Angiogenesis and microcirculation”, Salve Regina, USA − Intl symposium on “Hypertension” ("Forefronts of Hypertension"), Berlin, Germany. − International Workshop “Gene targeting”, Israel Academy of Science, Weizmann Institute, Rehovot, Israel − XIth International Symposium on Atherosclerosis, October 2-4, 1997, Bordeaux, France − XIth International Symposium on “Atherosclerosis”, October 5-10, 1997, Paris, France. − Intl Meeting “Cardiovascular Research in Europe: proposals for the future”, Rome, Italy. − Wood Symposium, October 29-30, 1997, Cleveland Clinic, Ohio, USA − VIth International Workshop “Molecular and Cellular Biology of Plasminogen Activation”, San Diego, USA − 70th International Meeting American Heart Association, Orlando, Florida, USA. − International Workshop on “Receptor Tyrosine Kinases”, Helsinki, Finland. − Intl Workshop “Cardiovascular specific gene expression”, Maastricht, the Netherlands. − Symposium on “Atherosclerosis: From Molecule to Man”, Physiological Society Meeting, Cambridge, UK. Keynote lecture

1998 − Conference American Association Cancer Research "Angiogenesis and Cancer", Orlando, Florida, USA. Plenary lecture − Gordon Research conference on “Thrombolysis”, Ventura, CA, USA

10 Peter Carmeliet

− Meeting British Society of Cardiovascular Research, London, UK − Annual Meeting “Gesellschaft Thrombose- and Hämostaseforschung”, Frankfurt, Germany. − Intl Meeting “The Genome Program: Applications to Cardiovascular Biology”, San Diego, USA. Plenary lecture − British Connective Tissue Society-Spring meeting, Cardiff, UK − International Vascular Biology Meeting (NAVBO), San Francisco, USA. Plenary Lecture − British Society of Cardiovascular Research Spring meeting, London, UK. − Intl American Thoracic Society/International Lung Organization meeting, Chicago, USA − Sigrin Juselius Symposium on “Angiogenesis”, Helsinki, Finland − International Meeting on “Proteinases in Tumor Biology”, Copenhagen, Denmark. Plenary Lecture − 14th International Congress on “Fibrinolysis and Thrombolysis”, Ljubljana, Slovenia. Plenary ISTF Prize Lecture − Gordon Research Conference on “Hemostasis”, Plymouth, New Hampshire, USA. − 27th Congress International Society of Haematology, Amsterdam, the Netherlands. − 70th European Association of Atherosclerosis, Genève, Switzerland. Plenary Lecture − Xth International Meeting on Vascular Biology, Cairns, Australia. − 5th International Franz Volkhard Symposium, Berlin, Germany − International Symposium on “Update on Thrombolysis 1998”, Berlin, FRG. − 13rd Seminar on Nephrology, October 15-16, 1998, Paris, France. − 2nd International Meeting on “Stunning, Hibernation, and Preconditioning”, Taormina, Sicily, − 3rd European Research Conference “Blood Pressure and Cardiovascular Disease”, Noordwijkerhout, the Netherlands. − Annual Meeting Hematology, Thrombosis & Hemostasis Societies, Tenerife, Canary Islands. − Forbeck Symposium on “Angiogenesis and accessibility”, South Carolina, USA. − International Meeting on “Mouse models of cardiology”, Amsterdam. Keynote address − Intl Symposium “Vascular Protection: From basic sciences to the clinic.”, Los Angeles, USA.

1999 − Intl Symposium on “Neoangiogenesis and the Endothelium”, Maastricht, the Netherlands − Symposium of the Imperial College School of Medicine, London, UK. Keynote speaker − 34th Annual Meeting of the German Diabetes Association, Frankfurt, Germany − Vth Saratoga International Conference on Atherosclerosis, Barcelona, Spain − 71st European Atherosclerosis Society Congress, Athens, Greece. Plenary lecture − 71st European Atherosclerosis Society Congress, post-congress symposium, Kos, Greece − 4th Congress of the European Hematology Association, Barcelona, Spain. Plenary Presidential Symposium Lecture − International Society for Heart Research, XXI Annual Scientific Meeting, San Diego, USA − FASEB meeting on “Thrombin and Vascular Medicine”, Vermont, USA − XXth Meeting European Section Intl Society of Heart Research,, Maastricht, the Netherlands. − Gordon Research Conference on “Atherosclerosis”, Meriden, New Hampshire. − Wolfson Institute for Biomedical Research, London, UK − 48th Symposium on the “Biology of Skin”, Snowmass Village, Colorado, USA − Gordon Research Conference “Angiogenesis and Microcirculation”, Newport, Rhode Island − European Society of Cardiology, Barcelona, Spain − International Symposium on Cardiovascular Biology, Cambridge, UK − Angiogenesis Meeting on Angiogenesis, Utrecht, The Netherlands. Keynote Lecture − First International Meeting on Vascular Medicine, Düsseldorf, Germany − International Symposium on “Heart Failure”, Rome, Italy

11 Peter Carmeliet

− International Symposium “Thrombosis and Coagulation”, Nordic Society of Thrombosis, Göteborg, Sweden − Intl Conference Angiogenesis and Tumors, European Society of Hematology, Paris, France − Annual Berne Lecture, University of Virginia, Charlottesville, Virginia, USA − Intl Meeting American Society of Nephrology, Florida, USA. State-of-the-Art Lecture − 1st US-European Meeting on Molecular Basis of Cardiovascular Diseases, Paris − Meeting of the French Society of Cancer, Paris, France

2000 − Conference of the New York Academy of Sciences, New York, USA − Keystone Symposium on “Molecular Biology of the Cardiovascular system”, Snowbird, Utah, USA − IBC Global Conference on “Therapeutic Control of Angiogenesis”, London, UK − Scripps Research Institute, La Jolla, California, USA − Keystone Symposium on “Angiogenesis”, Keystone, Colorado, USA. Plenary Lecture − Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, USA − The Wistar Institute, Philadelphia, USA − Symposium “Vascular Biology”, Dresden, Germany − 2nd Intl Symposium “Cardiovascular physiology of mice in vivo”, Amsterdam, The Netherlands − International Congress on “Angiogenesis”, Leiden, The Netherlands − Annual Meeting of the German Society of Cardiology, Düsseldorf, Germany − 19th World Congress of the International Union of Angiology, Ghent, Belgium − International Congress of the European Tissue Repair Society, Brussels, Belgium − International Symposium on “Etiology and Treatment of Coronary Arterial Thrombosis: Basic Science and New Clinical Approaches”, Chapel Hill, North Carolina, USA − First annual Spring meeting of the Council on Arteriosclerosis, Thrombosis, and Vascular Biology (ATVB) of the American Heart Association, Denver, Colorado − European Society of Microcirculation, Stockholm, Sweden − International Society for Heart Research, XXI Annual Scientific Meeting, Louisville, USA − International Conference on “Sudden death and Long-QT Syndrome”, Nice, France − Euroconference “Heart Failure: an epidemics of the 21st century”, Paris, France − XIIth International Symposium on Atherosclerosis, Stockholm. Plenary Lecture − Gordon Conference on “Vascular Biology”, New Hampshire, USA − Gordon Conference on “Thrombosis and Hemostasis”, New Hampshire, USA − International workshop on “Hypoxia and its role in Angiogenesis”, Ascona, Switzerland. − Angiogenesis and DMR, Washington, USA, June 22-23, 2000, Featured Lecture − 55th Congress of the Brazilian Society of Cardiology, Rio de Janeiro. Plenary Lectures − XXIIth Congress of the European Society of Cardiology, Amsterdam, The Netherlands − First “European Life Scientist Organization” (ELSO), Geneva, Switzerland − XIth International Vascular Biology Meeting, Geneva − International Angiogenesis Meeting, Seeon, Bavaria, Germany − 2nd Symposium on Vascular Biology, Münster, Germany, October 5, 2000. Key Note Lecture − XVth Congresso Nazionale della Societa Italiana di Cancerologica, Torina − EMBO Workshop, Nice, France − American Heart Association Meeting, New Orleans, USA, State of the Art Lecture. − 16th LIAC Latin meeting, on Lipid metabolism and related pathology, Lissabon, Portugal − International Meeting on “Tumor Angiogenesis: From Bench to Bedside”, Freiburg, Germany − 3rd Imperial College School of Medicine Symposium, London, U.K − 1st Hannover seminar on transplantation and vascular biology. Hannover, Germany − International Symposium on Vascular Biology, Kyoto, Japan

12 Peter Carmeliet

2001 − American Heart Association Meeting on Angiogenesis, Santa Fe, USA − Intl ABC/WIN (Neuroradiology/intervention) meeting, Val d’Isère, France, Keynote Lecture − Belgian Ass Cancer Research Meeting: “Tumor Hypoxia: friend or foe?”, Brussels, Belgium − Euroconferences on Angiogenesis, Paris, France. Keynote Lecture − 4th Dutch Atherosclerosis Society Symposium, Ermeloo, The Netherlands. Keynote Lecture. − 50th Annual Scientific Session of the American College of Cardiology, Bethesda, USA − 6th Saratoga International Conference on Atherosclerosis, Tokyo, Japan − Keystone Meeting on Angiogenesis & Chronic diseases, April 24-29 2001, Colorado, USA − Gordon Conference on Atherosclerosis, June 24-28 2001, Kimball Union Academy, USA − Gordon Conference on Atherosclerosis, Kimball Union Academy, USA − XVIIIth Congress Intl Society Thrombosis Hemostasis, Paris, France, State of the Art Lecture − XXIIIth Congress of the European Society Cardiology, Stockholm, Sweden − Euroconferences on Angiogenesis, Paris, France, Keynote Lecture − 35th Annual Meeting European Society Clinical Investigation, Barcelona, Spain − IVth International Meeting Platelets and Vascular Occlusion, Capri, Italy − Dutch Society Matrix Biology, Arnhem, The Netherlands, Keynote Lecture − 4th Annual Symposium on Angiogenesis and DMR, Washington DC, USA, Plenary lecture − XXIIth Congress European Society Cardiology, Amsterdam, The Netherlands − 46th Ann meeting German Society of Neuropathology & Neuroanatomy, Freiburg, Germany − 1st Interdisciplinary Euroconference on Angiogenesis, Paris, France − Meeting of Belgian Society for Cell Biology, Liege, Belgium − Angiogenesis Course, Harvard Medical School, Boston, USA − Gordon Research Conference “Angiogenesis and Microcirculation”, Newport, Rhode Island − French Society of Endocrinology Meeting, Liege , Belgium

2002 − Intl ABC/WIN (Neuroradiology/intervention) meeting, Val d’Isère, France, Keynote Lecture − Keystone Symposium on Molecular and Cellular Biology, Banff, Alberta, Canada − EMBO Workshop, 2nd IRCC International. Cancer Conference, Turino, Italy − Nobel Forum Lecture, Stockholm, Sweden (invited by Nobel Committee and Karolinska Institute) − Harvey’s Centennial Celebration Lecture, Padova, Italy − American Association Cancer Research Meeting, San Francisco, USA − Angiogenesis Course, Harvard Medical School, Boston, USA − Intl Symposium ‘Molecular Mechanisms of Pathogenesis’, Wurzburg, Germany − International Meeting ‘The Lymphatic continuum’, Lymphatic Research Foundation, NIH, Maryland, USA − XIIth International Vascular Biology Meeting, Karuizawa, Japan − Intl Meeting “Angiogenesis”, Monte Verita, Switzerland − Intl Symposium Exploring the Potential Cardiovascular Therapeutic Values of Protein, Gene, and Cell-Based Strategies for Angiogenesis and Myogenesis, Washington, USA − 20th World Congress of Dermatology, Paris, France, Plenary Lecture − 22nd ISHR meeting, Outstanding Investigator Prize, Hungary − 2nd Intern. Symp. of the German Priority Research Program: ‘Angiogenesis’ Kloster Seeon − 2nd Interdisciplinary Euroconference on Angiogenesis, Lisbon, Portugal − American Heart Association Meeting, USA, Plenary Lecture, Brown Lecture − Intl Conference on HIF/Hypoxia mediated responses in Tumor Biology, Manchester, UK − 8th meeting of the German Society of Neurogenetics, Ulm, Germany

13 Peter Carmeliet

2003 − Intl ABC/WIN (Neuroradiology/intervention) meeting, Val d’Isère, France, Keynote Lecture − Gordon Conference on ‘Vascular Cell Biology’, Ventura, CA, USA − CRT2003 meeting, Washington, USA − Ernst Schering Lecture, Berlin, Germany − 6th European Congress of Endocrinology, Plenary Lecture, Lyon, France − Angiogenesis Course, Harvard Medical School, Boston, USA − 8th Congress of the EHA, Plenary Lecture, Lyon, France − Gordon Conference on ‘Atherosclerosis’, New Hampshire, USA − International meeting ‘Angiogenesis in Cancer’, Reykjavik, Iceland − XIXth Congr ISTH, Plenary Lecture, Birmingham, UK − Gordon Conference on ‘Angiogenesis and Microcirculation’, Newport, RI, USA − 1st Annual Atherothrombosis Summit, Cleveland, Ohio, USA − XIIIth International Symposium on Atherosclerosis, Kyoto, Japan − Intl Society of Atherosclerosis Sattelite Symposium, Kobe, Japan − American Association Cancer Research, Angiogenesis meeting, Chicago, USA − 3nd Interdisciplinary Euroconference on Angiogenesis, Dublin, Ireland − First BJP Symposium, Intl AHA Meeting, Orlando, USA − Perspectives in Molecular Medicine Lecture, Frankfurt, Germany

2004 − Keystone Symposium on ‘Angiogenesis’, Santa Fe, New Mexico, USA − AIDS-related cancer meeting, London, UK − 1st Developmental Vascular Biology Workshop, NAVBO, Asilomar, CA, USA − Babraham Institute Lecture, Cambridge, UK − Cancer Seminar Series, Vall d´Hebron Univ Hospital Research Institute, Barcelona, Spain − Franqui Colloquium, Brussels, Belgium − Cancer Meeting, Milan, Italy − Gordon Research Conference on ‘Molecular Mechanisms in Lymphatic Function and Disease’, Ventura, USA − Keystone Symposium on ‘The biology of Hypoxia’, Steamboat Springs, Colorado, USA − CRT 2004 meeting, Washington, USA − Einthoven lecture, Weinstein Symposium, Leiden, Netherlands − 3th ESH Interdisciplinary Euroconference on Angiogenesis, Helsinki, Finland − Benditt Award Lecture, North Atlantic Vascular Biology Assoc (NAVBO), Toronto, Canada − Angiogenesis Course, Harvard Medical School, Boston, USA − 36th Japanese Atherosclerosis Society Meeting, Fukuoka, Japan − World Congress of Gastro Intestinal Cancer, Barcelona, Spain − 3rd Annual Symposium on ‘Anti-Signalling Strategies in Human Neoplasia’, Barcelona, Spain − Kloster Seeon Meeting Angiogenesis, Chiemsee, Germany − Darthmouth Life Sciences Symposium, Hanover-New Hampshire, USA − American Society of Nephrology Congress, St Louis, MI , USA, Keynote Lecture − Nobel Conference on Oxygen Biology, Stockholm, Sweden − International Symposium on ALS/MND, Philadelphia, USA, State-of-the Art Lecture

2005 − Intl ABC/WIN (Neuroradiology/intervention) meeting, Val d’Isère, France, Keynote Lecture − European Society of Human Genetics, Prague, Czech Republic

14 Peter Carmeliet

− Keystone Symposium on ‘Molecular Biology of Cardiac Diseases and Regeneration, Steamboat Springs, Colorado, USA − 1st Annual ARVO/Pfizer Ophtalmics Research Institute Conference, Fort Lauderdale, USA − 4th ESH Interdisciplinary Euroconference on Angiogenesis, Sitges, Spain − Angiogenesis Course, Harvard Medical School, Boston, USA − Gordon Conference on ‘Angiogenesis and Microcirculation’, Newport, RI, USA − 2nd International Conference on Angiogenesis, Monte Verita, Switzerland − ICRH Distinguished Lecture and Price in Cardiovascular Sciences, Institute of Circulatory and Respiratory Health, Vancouver, Canada − Special AACR Conference on ‘Anti-Angiogenesis and Drug Delivery to Tumors: Bench to Bedside and Back’, Boston, USA − Society for Neuroscience meeting, Special Symposium on ‘Novel Directions in Neural-Vascular Interactions’, Washington, USA − 28th Congress of the Japanese Society of Thrombosis and Hemostasis, "Moleculo-medical Exploration of Blood-Vascular Interface", Fukuoka, Japan, Special Lecture − 3rd Annual “Angiogenesis in Drug Discovery & Development Summit”, Cambridge, MA, USA, Keynote Lecture − International Conference on "Exploring the Future of Vascular and Inflammatory Mediators", Lund, Sweden, Keynote Lecture

2006 − Intl ABC/WIN (Neuroradiology/intervention) meeting, Val d’Isère, France, − Keystone Symposium ‘Hypoxia and Development, Physiology and Disease’, Breckenridge, CO, USA − 2nd Developmental Vascular Biology Workshop, NAVBO, Asilomar, CA, USA − Feodor Lynen Lecture, Nature Biotechnology Winter Symposium, Miami, USA − Keystone Symposium on Atherothrombosis/Molecular Biology of the Vasculature, Keystone, CO, USA − Oncoforum, Brussels, Belgium − 6th ESH Conference on Angiogenesis, Mandelieu-Nice, France − 19th International Congress on Thrombosis, Tel Aviv, Israel, Plenary Lecture − Days of Molecular Medicine Symposium, Stockholm, Sweden − Angiogenesis Course, Harvard Medical School, Boston, USA − XIVth International Vascular Biology Meeting, Noordwijkerhout, The Netherlands − 18th Annual Pezcoller Symposium, Trento, Italy − FENS Satellite Workshop, Keynote Lecture, Vienna, Austria − Gordon Research Conference on Lymphaniogensis, Les Diablerets, Switzerland − JAMR Presidential Symposium, Tokushima, Japan − Special Presidential Lecture, Neuroscience Meeting, Atlanta, USA − 3rd International Symposium on Angiogenesis and Cancer, Malaga, Spain − Holst Memorial Lecture, University of Eindhoven, Netherlands − Third NBRC International Conference, New Delhi, India

2007 − Intl ABC/WIN (Neuroradiology/intervention) meeting, Val d’Isère, France, − Keystone Lecture, 9th International Symposium on anti-angiogenic agents, San Diego, USA − European Society Cardiology W. Harvey Lecture on Basic Science, ESC meeting, Vienna, Austria − American Association for Cancer Research Annual Meeting, Los Angeles, USA − 8th Congress of the French Neuroscience Society, Montpellier, France − 3rd Meeting “Molecular Mechanisms of Neurodegeneration”, Milan, Italy

15 Peter Carmeliet

− 7th ESH Conference on Angiogenesis, Algarve, Portugal − Angiogenesis Course, Harvard Medical School, Boston, USA − 4th IRCC International Cancer Conference, Torino, Italy − 5th European Zebrafish Meeting, Amsterdam, The Netherlands − International Society for Neurochemistry, Cancun, Mexico − Gordon Research Conference on Angiogenesis, Newport RI, USA − 4th IC on Thrombosis and Hemostasis Issues in Cancer, Bergamo, Italy − 3rd International Conference of Tumor Stroma Interaction, Monte Verita, Ascona, Switzerland − Breast Cancer and Metastasis Conference, Rome, Italy

2008 − Intl ABC/WIN (Neuroradiology/intervention) meeting, Val d’Isère, France, − Keystone Symposia - Angiogenesis and Hypoxia, Vancouver, Canada − Frontier Science in the Netherlands, Erasmus MC Rotterdam, Netherlands − 87th Annual Meeting German Physiological Society, Köln, Germany − ISCO Congress 2008, Amsterdam, Netherlands − Nobel Forum Lecture, Stockholm, Sweden − European Society for Clinical Investigation Annual Meeting, Geneva, Switserland − NAVBO – Experimental Biology Meeting, San Diego, USA − TRM Oncology - 3rd Angiogenesis course, Barcelona, Spain − ESH 8th Conference on Angiogenesis, Paris, France − World Biomaterial Congress 2008, Amsterdam, Netherlands − 23rd Annual Critical Issues in Tumor Microcirculation, Angiogenesis and Metastasis Course, Boston, USA − Hypertension 2008 Conference, Berlin, Germany − Communities in Practice : Leuven Lung Cancer Group, Leuven, Belgium − CNIC 1st Cardiovascular Symposium, Madrid, Spain − 30th Annual ASBMR, Montreal, Canada − 5th International Kloster Seeon Meeting, Seeon, Germany − From the lab to the clinic : Mechanisms of Disease Chronicity, Trinity College Oxford, UK − Koninklijke Belgische Academie voo Geneeskunde - Angiogenese, Brussel, Belgium − Académie Royale de Médecine de Belgique, Bruxelles, Belgie − BioSymposia : Hypoxia, Ischemia, and Inflammation: Essential Connection, Boson, USA − International Symposium on Angiogenesis and Cancer, University of Malaga, Spain − 31st Congress of the Japanese Society for Thrombosis & Haemostasis, Osaka, Japan

2009 − Keystone Symposium - Angiogenesis and Lymphangiogenesis in Cancer, Big Sky, Montana, Canada − European Union network of Excellence "Cells into Organs” Meeting “Tissue Specification and Organogenesis”, Gulbenkian Foundation, Lisbon, Portugal − Dahlem Colloquium, Max Planck Institute, Berlin, Germany − Gordon Research Conference - Vascular Cell Biology, Ventura, USA − 1st Joint Meeting of the Swiss and German Society of Cell Biology (ZMG/GDZ), Konstanz, Germany − Leopoldina Sateliet Symposium on Neuro-Immune Cross Talk, Antwerpen, Belgium − AACR 100th Annual Meeting, Denver, USA − Annual Meeting of the Spanish Society for Atherosclerosis, Pamplona, Spain − EMBO Vascular (Developmental) Biology workshop, Helsinki, Finland − 2009 Annual Tumor Course: Critical Issues in Tumor Microenvironment, Angiogenesis and

16 Peter Carmeliet

Metastasis, Harvard Medical School, Boston, USA − EACR Conference - Inflammation and Cancer, Berlin, Germany − 25. Ernst Klenk Symposium in Molecular Medicine on Cellular Matrix in Health and Disease, Cologne, Germany

2010 − Keystone Symposium - Hypoxia: Molecular Mechanisms of Oxygen Sensing and Response Pathways, Colorado, USA − Keystone Symposium - Angiogenesis in Health and Disease, Colorado, USA − Keystone Symposium - Metabolism and Cancer Progression, Vancouver, Canada

17