Anti-CNTNAP4 / Caspr 4 Antibody (ARG43335)

Product datasheet [email protected]

ARG43335 Package: 50 μl anti-CNTNAP4 / Caspr 4 antibody Store at: -20°C

Summary

Product Description Rabbit Polyclonal antibody recognizes CNTNAP4 / Caspr 4

Tested Reactivity Hu, Ms

Tested Application WB

Host Rabbit

Clonality Polyclonal

Isotype IgG

Target Name CNTNAP4 / Caspr 4

Species Human

Immunogen Synthetic peptide derived from Human CNTNAP4 / Caspr 4.

Conjugation Un-conjugated

Alternate Names CASPR4; Cell recognition molecule Caspr4; Contactin-associated protein-like 4

Application Instructions

Application table Application Dilution

WB 1:1000 - 1:3000

Application Note * The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Positive Control LoVo

Observed Size ~ 145 kDa

Properties

Form Liquid

Purification Affinity purification with immunogen.

Buffer PBS (pH 7.4), 150 mM NaCl, 0.02% Sodium azide and 50% Glycerol.

Preservative 0.02% Sodium azide

Stabilizer 50% Glycerol

Concentration 1 mg/ml

Storage instruction For continuous use, store undiluted antibody at 2-8°C for up to a week. For long-term storage, aliquot and store at -20°C. Storage in frost free freezers is not recommended. Avoid repeated freeze/thaw cycles. Suggest spin the vial prior to opening. The antibody solution should be gently mixed before use.

Note For laboratory research only, not for drug, diagnostic or other use.

www.arigobio.com 1/2 Bioinformation

Gene Symbol CNTNAP4

Gene Full Name contactin associated protein-like 4

Background This gene encodes a member of the neurexin protein family. Members of this family function in the vertebrate nervous system as cell adhesion molecules and receptors. This protein contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like domains. This protein may also play a role in proper neurotransmission in the dopaminergic and GABAergic systems and mutations in this gene may be associated with certain psychiatric illnesses. A polymorphism in an intron of this gene may be associated with longevity. [provided by RefSeq, Apr 2016]

Function Presynaptic protein involved in both dopaminergic synaptic transmission and GABAergic system, thereby participating in the structural maturation of inhibitory interneuron synapses. Involved in the dopaminergic synaptic transmission by attenuating dopamine release through a presynaptic mechanism. Also participates in the GABAergic system (By similarity). [UniProt]

Calculated Mw 145 kDa

Cellular Localization Cell junction, synapse, presynaptic cell membrane; Single-pass type I membrane protein. Note=Specifically present within the presynaptic compartment of synapses. [UniProt]

Images

ARG43335 anti-CNTNAP4 / Caspr 4 antibody WB image

Western blot: LoVo whole cell lysate stained with ARG43335 anti- CNTNAP4 / Caspr 4 antibody.