Christopher M. Barker and William E. Walton Co-Directors PacVec At-A-Glance

Research

Collaboration Training & Community Theme 1: Field evaluation of surveillance and control • Predicting efficacy of field adulticiding from bottle bioassays and kdr frequency (Cornel)

• Monitoring tolerance to bacterial insecticides used for vector control (Gill)

• Sustainable use of pesticides in complex urban and suburban environments (Gan) Theme 2: Next-generation surveillance technologies • Enhance arbovirus surveillance (Coffey, Le Roch)

• Improved traps for mosquito detection (Carde)

• Next-generation trapping technologies (Keogh) Theme 3: Innovative control methods & evaluation

• Genetic estimates of Aedes aegypti abundance and dispersal to inform control strategies (Lanzaro, Lee)

• Using the piRNA system of Aedes and Culex to engineer immunity to human pathogens (Atkinson)

• Recombinant bacteria for mosquito control (Federici) Theme 4: Epidemiology and vector ecology

• Epidemiology of tick-borne pathogens in the southwestern US (Foley) • Define geographic and seasonal variation in urban Aedes densities to improve surveillance and control strategies (Barker) • Distribution and control of Aedes in phytotelmata (Walton) Training and Collaboration Undergraduate, graduate, and • Vector ecology/public health postdoctoral training entomology • Direct training opportunities Medical outreach • Small grants program • CME training for physicians • Internships with VCDs • Integration of VBD material into medical and veterinary curricula Continuing Education • Engagement of CoE investigators Citizen Science in regional CE in • USDA Invasive Mosquito Project • Extension of training to AZ, HI, (moved to UCR) Guam, other Pacific Islands Workshops National public health • Insecticide resistance organizations • Arbovirus testing and biosafety • CSTE, NACCHO PacVec Training Grants

• $900,000 ($600K CDC + $300K UCD) to be awarded 2018-2021 • 1- year projects up to $25,000 • Support for research stipend+supplies and travel for trainees (graduate or undergraduate students, postdocs) • Open to investigators in CA, AZ, NV, HI, UT and USAPIs Training Program: Awards FY 2018

Project Title Collaborating Agencies State University (Swei, Sambado) California Assessment of risk and transmission cycle of the Department of Public Health - Vector-borne Disease emerging tick-borne pathogen, Borrelia miyamotoi Section, UC Davis - One Health Institute

Genomic basis of mammal-biting in Culex pipiens, UC Santa Cruz (Kilpatrick, Haba) Multiple CA, OR, WA, NV a primary vector of WNV mosquito control agencies

Northern University (Hepp, Ridenour) Coachella Circulation of St. Louis encephalitis virus in the Valley MVCD, Maricopa Country Environmental Services southwestern Department Vector Control Division

Is adaptation mal adaptation: an assessment of University of Arizona (Brown, Shilan) Pima County Health mosquitoes and water harvesting Department, City of Tuscon Water District

University of Arizona (Ernst, Arnbrister) Arizona Engaging community health workers for vector Department of Health Services Vector-borne Disease and control and surveillance Zoonotic Disease Program, Border Infectious Disease Surveillance Officer

Genetic variation and endosymbiont diversity of University of Arizona (Walker, Brophy) Arizona Department Rhipicephalus sanguineus populations across of Health Services Arizona

University of the Pacific (Thiemann, De La Vega, Ryan) Lake Pyrethroid resistance in Culex tarsalis County VCD, Placer MVCD, Sacramento-Yolo MVCD, San Joaquin County VCD PacVec Training Grants

• Go to pacvec.us and click “Funding Opportunities” • Preference for (1) collaboration with public health of vector control (2) matching funds from collaborators (3) compelling plan for public health-related career • 2019 call for proposals in January https://www.naccho.org/uploads/downloadable-resources/Mosquito-control-in-the- U.S.-Report.pdf Percentage of vector control organizations carrying out pesticide resistance testing Of the vector control organizations ranked as Needs Improvement, nearly all of them (98%) lack the capability or capacity to perform pesticide resistance testing.

https://www.naccho.org/uploads/downloadable-resources/Mosquito-control-in-the- U.S.-Report.pdf PacVec Training Videos Overview of Larval Mosquito Bioassays Bioassays using Bacterial Larvicides Bioassays using Spinosad Bioassays using Methoprene https://youtu.be/5ulNOaB4nNM Bottle Bioassays for Adult Mosquitoes PacVec Seminars and Brown Bag Discussions Monthly seminars - 2nd Tuesday of each month - Alternating between UCD and UCR with webcast to other campus - Open to public health and vector control collaborators

Brown bag discussions - On/around 4th Tuesday of each month - Arranged separately on UCD and UCR campuses - Postdocs and graduate students present and discuss proposed research or work in-progress PacVec Seminar Series Available through Zoom to subscribers to https://pacvec.us - Second Tuesday of each month during the academic year Video archive: https://www.youtube.com/playlist?list=PLn8A0VsfhF9ithvW50pyiYpeFY7yBAPK2 Community of Invasive Aedes maps Practice: PacVec Services • R&D for new surveillance and control technologies • Diagnostic test development Arbovirus maps • Vector genetics and genomics • Bottle bioassay training and testing • PH pesticide deposition, degradation and environmental fate • Data management & analytics • Expansion to other states and territories: Guam, Pacific Islands, , New Jersey Connect with us! Website: pacvec.us Twitter: @PacVecCenter 19 https://www.cdc.gov/parasites/education_training/lab/bottlebioassay.html