Astellas Pharma US, Inc. Company Facts

U.S. Headquarters Astellas Pharma US, Inc./Astellas US LLC Major Pharmaceutical Products Three Parkway North Deerfield, IL • VESIcare® (solifenacin succinate) 60015-2548 is indicated for the treatment of with symptoms of urgency, Global Headquarters frequency, and urge incontinence. Astellas is Astellas Pharma Inc. 3-11, partnered with GlaxoSmithKline for the co- Nihonbashi-Honcho 2-chome promotion of VESIcare. Chuo-ku 103-8411, • Prograf® () is indicated for the prophylaxis of organ rejection in patients receiving kidney or liver transplants. • Mycamine™ (micafungin sodium) is U.S. Management the product for prophylaxis of Yoshihiko Hatanaka, Ph.D. Candida in patients undergoing Chairman and CEO hematopoietic stem cell transplantation and Astellas Pharma US, the treatment of esophageal candidiasis. Inc./Astellas US LLC • Protopic® (tacrolimus ointment) is Global Management used to treat eczema (atopic dermatitis). • Adenoscan® (adenosine injection) is Masafumi Nogimori, a pharmacologic stress agent indicated as Ph.D. an adjunct to thallium-201 myocardial President and CEO perfusion scintigraphy in patients unable to Astellas Pharma Inc. exercise adequately. Company US Web site • Adenocard® (adenosine injection) is www.astellas.com/us indicated for the conversion to sinus rhythm of paroxysmal supraventricular tachycardia (PSVT) Company Global Web site • AmBisome® (liposomal www.astellas.com ) is a sterile, non-pyrogenic Financial Figures lyophilized product for intravenous infusion 2004 Combined Yamanouchi and Fujisawa and a true single bilayer liposomal drug Forecasted Earnings (fiscal year ending delivery system. March 2005) • Flomax® is indicated for the • 849 billion yen in sales (approximately treatment of functional symptoms of benign $7.8 billion) prostatic hyperplasia. Astellas is partnered • 176 billion yen in operating income with Boehringer Ingelheim Pharmaceuticals, Inc. for the copromotion and Abbott (approximately $1.6 billion) Laboratories, Inc for distribution. Number of Employees Current Workforce • Approximately 17,000 people worldwide The Astellas Name The Astellas name Concentrated Therapeutic Areas signifies the company’s aim to deliver hope • to people through stateof-the-art • Infectious disease pharmaceutical products and to grow into a • Dermatology single, global mega pharmaceutical • company with worldwide headquarters in • Cardiovascular disease Japan. Astellas expresses the idea of “aspired stars” and “advanced stars” based on Latin “stella,” Greek “aster,” and English “steller,” which all refer to stars.