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2 WELCOME FESTIVAL AT A GLANCE DIRECTOR’S PICKS

Thank you to all those who have From an exploration of Shakespeare’s medicine cabinet to an evening of gin sampling and the UK’s contributed to the inspirational DISCOVER MORE AT SCIENCE FESTIVAL BIG THINKERS best science talent competition, Programme Director Sharon Bishop gives us an insider’s look at 2013 Festival programme, in the 2013 Science Festival… particular our Guest Directors – … WITH MEMBERSHIP FAVOURITES My Sister Rosalind Franklin p.11 computer scientist Dame Wendy Science Question Time p.12,17,20,24 Jocelyn Bell Burnell p.13 Hall, Science Minister David Willetts and comedian Dara O FameLab International Final p.25 Martin Rees: Surviving The PRIORITY BOOKING MUST LOVE LITERATURE? START HERE… Briain – who’ve added a generous Call My Genetically Century p.13 James Watson in Conversation with Matt Ridley (p.19) Pride, Prejudice and the Doctor (p.26) dose of their own ideas and Engineered Bluff p.38 James Watson p.19 Peter Higgs in Conversation with Dara O Briain (p.17) Do you Judge a Book by its Cover? (p.17) enthusiasm to the programme. The Over-Ambitious Demo Peter Higgs & The Higgs Boson: I’m so excited to welcome two of the world’s greatest living I love it when the Festivals come together, as we get to PROF. RUSSELL FOSTER Professor Russell Foster scientists to the Festival this year. James Watson drew a do things you simply wouldn’t find anywhere else – like FESTIVAL CHAIR Challenge 2013 p.40 From Theory To Reality p.19 Festival Chair line under one of the greatest races in science when he teaming the worlds of publishing and neuroscience to discovered the structure of DNA, and Peter Higgs’ ideas explain our reading choices and pairing a crime author inspired one, the well-publicised search for the “God and forensic psychologist to look inside the criminal mind FULL THE UNIVERSE THE HUMAN BODY HIGH TECH Particle.” This is an amazing chance to see two men whose (p.12). There’s a fresh perspective on our best-loved writers thinking has changed our understanding of the world: too in Shakespeare’s Medicine Cabinet (p.35) and a look at MEMBERS Jodrell Bank p.15 Hormone Fight Club p.11 Dementia Care And don’t miss it. how scientific thinking in Regency England affected Jane • Book first for top events SAVE 10% Exoplanet Explorers p.19 Bumpology p.23 Touch Screen Technology p.11 Austen’s plots and characters. • Save 10% on your tickets* Quantum Biology p.24 Michael Berkeley: Coding The Game p.20 • Save 5% at the Waterstones Festival The Kuiper Belt p.25 Hearing In A Creative World p.25 Fly-Sized Spies p.20 book tent* Mars Curiosity: Anatomy Scan: LIVE p.33 How Safe Is Your WiFi? p.24 DISCOVER SOMETHING NEW BRING YOUR FRIENDS PROFESSORS KATHY SYKES AND MARK LYTHGOE Join online at cheltenhamfestivals.com or The NASA Rover p.38 The Life Of Brain p.34 Raspberry Pi Workshop p.32 FameLab International Final (p.25) Botany of Gin (p.13) The Kuiper Belt (p.25) FESTIVAL DIRECTORS Great Comets (p.26) Stargazing (p.26) visit the Members’ Desk during the Festival One of my favourite parts of the Festival is discovering new From asking what makes the world turn to seeking out talent, so I love FameLab: our international competition to Gin. Need I say more? Plan a night out with a difference, the secrets of the perfect cuppa, our Science Festival is find the science stars of the future. It’s not easy to stand full of cocktails and chemistry. Or if space and the night all about asking questions. And the best thing is that – *Discounts and offers are exclusively for Full and Founding on a stage and captivate the audience with big ideas in skies are your thing then Friday night’s the time to be just like you don’t have to play an instrument to enjoy Members’ sole use and do not apply to Associate Members. YOUR HEALTH ANIMAL KINGDOM a music festival – you don’t have to be good at science Advance booking is for each Member and a guest. just three minutes, but the FameLabbers do it beautifully. out. Catch two prizewinning scientists from the US who to enjoy it. Just come armed with a curious mind and a Maurice Saatchi’s Medical The Origins Of Society p.11 Past FameLabbers have gone on to present on stages and discovered the Kuiper Belt (p.25), then an event on Great question or two! Find videos, interviews and more online at Innovation Bill p.13 Africa: Eye To Eye p.12 screens around the world, and the grand international final Comets (p.26), and top it off with a little stargazing in The Truth About Flu p.19 – featuring winners from 21 countries – takes place right Imperial Gardens. Fingers crossed for clear skies! At this year’s Festival we’ll be hosting some of our most cheltenhamfestivals.com/science The Ugly Animal Preservation here in Cheltenham. Don’t miss it. surprising, inspiring and explosive events yet. We’ll be Intensive Care With Kevin Fong p.24 Society p.26 exploring some of the last century’s landmark scientific discoveries with big thinkers Peter Higgs, James Watson Is My Immune System Normal? p.32 Animal Diaries p.37 and Jocelyn Bell Burnell, and looking to the future with a How is a butterfly wing like an iPad? Pain: Why Does It Hurt A Dog Nose Best p.38 focus on cutting-edge research. So Much? p.37 But it’s not just about the main events. Our Festival What does purple sound like? YOU CAN HELP MAKE A DIFFERENCE bubbles with the thrill of discovery in all the free venues Can an Act of Parliament cure cancer? Every booking includes a suggested voluntary donation, and if and activities as well – you can get hands-on with you’re able to give this we would really appreciate it. experiments in the Discover Zone; explore the future Is man-flu make-believe? FAMILY FRIENDLY SOMETHING LITERARY Since ticket sales cover less than half of our annual costs, of technology in Area 42; meet BBC producers and We’ll be asking our scientific friends some very supporting the Festivals you love with a donation makes a real presenters in the BBC Science Zone; or just browse the As If By Magic p.43 DIFFERENT DIVERSIONS big questions in the run-up to the Festival in June. difference, and allows us to nurture great talent and reach more Waterstones book tent, have a coffee in The Times Café Daredevil Labs: Everest p.44 Botany Of Gin p.13 Just So Science p.12 Join in the fun on Twitter and Facebook. people with free and educational events. and soak up the vibrant atmosphere. Albert Einstein: Relativitively The Colour Of Music p.21 Do You Judge A Book By Its Finally, thank you to all our wonderful sponsors and @cheltfestivals #cheltscifest Thinking Without Words: Cover? p.17 There are all kinds of ways you can help to secure the Festivals’ Speaking p.33 future, including individual donations, corporate sponsorship partners who make the Festival possible. Many of them facebook.com/cheltenhamfestivals The Tango p.34 Pride, Prejudice & The Doctor p.26 will be bringing their latest research, experiments and The Big Book Of Natural Lab Notes: Songs About Shakespeare’s Medicine and remembering the Festivals in your will. Your support, no matter what size, will make a difference to our work. Thank you. gadgets for you to play with at the Festival. History p.45 Science p.40 Cabinet p.35 We hope that you too can join us this summer to Science Misadventures p.45 Stand-up Maths p.35 Inside The Criminal Mind p.12 Find out more: cheltenhamfestivals.com/support-us celebrate the sheer variety, joy and surprise of science. Professors Kathy Sykes and Mark Lythgoe Festival Directors

3 4 5 FESTIVAL MAP AND FREE ACTIVITIES

…A WHOLE YEAR OF TOP TWEETS EDF ENERGY ZONE KNITTING CORNER FREE Every day SCIENCE Crafters from The Perovskite Project are knitting and crocheting SCIENCE ZONE CHELTENHAM FESTIVALS JOIN THE CONVERSATION their way to a giant model of the mineral Perovskite! They will be Cheltenham Festivals is unique: where else could you dance the The POD is EDF Energy’s Education TOWN HALL in the Waterstones Book Tent during the Festival so make sure Suitable for all ages Programme. Come and talk to staff IN THE you visit them – you could even have a go yourself! Complete FREE Thurs, Fri, Sat & Sun night away at a Prohibition-era Speakeasy, learn the science about how they work with PILLAR ROOM beginners to experienced crafters welcome. of zombie fighting, lose yourself in a sublime piano recital or schools and take part Meet the production teams Jan @janh1 SQUARE DISCOVER responsible for some of your favourite meet JK Rowling and Kofi Annan on the same weekend? in fun hands-on ZONE Very very excited at the thought of activities all week. BBC science programmes, explore the If you’d like to make the most of everything that Cheltenham Madeleine Peyroux and Van the Man HEAD SQUEEZE content further, get hands-on with jointhepod.org science and have the opportunity to has to offer, or would simply like to support the work we do, at Chelters Jazz Festival this year!! The team behind YouTube channel then becoming a Cheltenham Festivals Member is a brilliant Wooohoooo!!!!! quiz their family of expert presenters Head Squeeze will be bringing the in an informal setting. place to start. But whichever way you choose to enjoy them, best of the channel to the Festival, THE TIMES CAFE Niamh Shaw @niamhiepoos PARABOLA GE PAVILION EDF and they’re looking for the questions Visit cheltenhamfestivals.com/ we wish you a wonderful Festival year. AREA 42 ARTS CENTRE EDF ENERGY @marklythgoe Congrats on a terrific that you’re dying to know the answer bbc-science-zone for more details on EUREKA ENERGY ARENA content and sessions. ‘I had no idea of half the stuff that was even festival. My first #cheltscifest and Interactive science for over 14s TALKING TENT ZONE to! You’ll find the team around the every event has been a cracker. And Fri 3 – 8pm, Sat 12 – 8pm, POINT site wearing trademark Head Squeeze on in Cheltenham until I became a Member.’ Sun 12 – 6pm FREE T-shirts. its only Wed! BBC EXPERITENT Festivals Member youtube.com/headsqueeze Get hands-on with some of the most SCIENCE Arakwai, Glaws @Arakwai ZONE exciting cutting-edge research and BOX OMG! OMG! OMG! Peter Higgs! technology. OFFICE WINTON Jocelyn Bell Burnell! SQUEEEEEEE! cheltenhamfestivals.com/area42 CRUCIBLE :-D #CheltSciFest MRC HELIX James Quinn @JamesEQuinn THEATRE WATERSTONES AREA BOOK TENT ART AT THE FESTIVAL Last night’s performance of DISCOVER ZONE 42 Rachmaninov’s Vespers by Ex FREE Cathedra was just exquisite. My Interactive science for all ages 10am – 5pm daily FREE As part of the COS13 art trail, artists favourite concert in @cheltmusicfest from Cheltenham Open Studios will so far. Open every day of the Festival, be exhibiting in the Town Hall’s Spa the Discover Zone gives children Well (near to the front entrance). GE PAVILION dan @danniroo the opportunity to get hands-on Come along to see some local work! with interactive technology and Associate Membership Full Membership seen the @cheltfestivals list and SCIENCE EVENTS Suitable for all ages from experiments. TALKING POINT FREE Every day getting oh so excited! sorting our QUEEN’S HOTEL Priority privileges Priority privileges Our purpose built venues play host to £30 membership out this wkend! My cheltenhamfestivals.com/ 100s of events throughout the 6 days An event got you thinking? Continue ROWING THE Get to grips with some of GE’s • Priority booking for + discounts favourite week of the year discoverzone of the Festival. There are lots of free the debate with the speakers and cutting-edge aircraft technology: use other audience members at the ATLANTIC you and a guest All Associate benefits, plus events too! computer programming to control Talking Point. Meet the local team who will be James Mayhew @mayhewjames Messier-Bugatti-Dowty aircraft components, inflate a balloon • Advance brochures • 10% ticket discount* Visit cheltenhamfestivals.com/ rowing across the Atlantic this @cheltfestivals @ChickCorea science/whats-on to browse events. without touching it and see how you and previews December, and find out all about from • Special Festival offers @NickyBenedetti fare in a full-sized flight simulator. the competition they are running to Plus much more... • Invitations to • Year round offers @KermodeMovie @TheCBSO design an experiment for the boat. special events £15 I’m honoured to be mentioned in such MEMBERS They’ll be next to the EDF Energy SAVE IN K Arena all week. company! BOX OFFICE THE BOO AND INFO POINT TENT Visit rowingtheatlantic2013.com/ schools for details Open in Imperial Gardens every day WAYS TO JOIN cheltenhamfestivals.com/subscribe of the Festival from 9.30am until the OUTDOOR ACTIVITIES start of the last event of the day. Open daily from 9.30 to Festival close. Online at cheltenhamfestivals.com/membership @cheltfestivals #cheltscifest The Waterstones Book Tent stocks a SEE Suitable for all ages Call 0844 880 8094 wide range of science titles and will PAGE 50 facebook.com/cheltenhamfestivals Sat & Sun from 11am be hosting author signings. FOR OTHER In person at the Regent Arcade Box Office FESTIVAL Interactive activities for all the Family At the Festival at the Members’ desk in Imperial Gardens. VENUES

JIM AL-KHALILI SWINGLE SINGERS MAKE 2013 CHELTENHAM THE TIMES CHELTENHAM MARK KERMODE CHELTENHAM A FESTIVAL JAZZ FESTIVAL SCIENCE FESTIVAL MUSIC FESTIVAL 1-6 MAY 4-9 JUNE NICOLA BENEDETTI 3-14 JULY LUCY WORSLEY YEAR! Members’ booking from 25 Feb Members’ booking from 15 Apr Members’ booking from 25 Mar Public booking from 4 Mar Public booking from 22 Apr Public booking from 2 Apr RAVI COLTRANE ALICE ROBERTS 6 7 8 GUEST DIRECTORS

WENDY HALL DAVID WILLETTS DARA O BRIAIN Dame Wendy Hall is Professor of As Minister for Universities and Comedian, presenter and theoretical Computer Science at the University Science, Rt Hon David Willetts physics graduate Dara O Briain of Southampton and is one of the is at the forefront of scientific joins us to explore his love of all most influential people working policy in the UK. An advocate for things scientific. The frontman of in UK I.T. One of the first computer the study of STEM subjects and BBC 2’s Science Club and Stargazing scientists to undertake serious public communication of science, Live, Dara is a keen astronomer research in multimedia and David is a regular visitor to Science with a curious mind. Throughout hypermedia, she has been at its Festivals across the country. He the Festival he’ll be flexing his forefront ever since. Wendy joins joins us in Cheltenham to explore scientific muscle in an interview with us in Cheltenham to explore how the challenges facing science and Professor Peter Higgs, pitting brains the internet impacts on our society, innovation in the UK today. against brawn in School of Hard shapes how we think and changes Sums, and hosting a live Science the way we interact with each other ‘Cheltenham is one of the Club with some special guests from and the world around us. country’s great science festivals the show. – with an amazing atmosphere ‘Cheltenham Science Festival “I am delighted to be returning to the and fascinating selection of Festival as Guest Director this year, a surprises me because of the things to do. Festivals offer a role that allows me not just to indulge appetite for science I see there. unique opportunity for scientists my scientific passions, whether in From children all the way up to and experts to share their maths or physics or video games, but adults and experts, the audiences ideas with the public and start which also historically grants me the real conversations about their right to graze cattle on the square here – as well as the topics – are so and shoot Welshmen with a bow and diverse and people just love it!’ research. It’s great to see what arrow from the city walls. Sadly, with quality science communication live versions of both School of Hard we have in this country, and this Sums and Science Club to host as well Festival is at the forefront of that.’ during the Festival, I won’t have time to do either. Another time!”

WENDY’S EVENTS DAVID’S EVENTS DARA’S EVENTS Is The Web Changing Society? p.33 Science, The Economy And You p.21 Coding The Game p.20 The Web And Us p.32 The Eight Great Technologies p.23 Peter Higgs In Conversation With Dara O Briain p.17 Cyber Security Conference p.10 Farming For The Future? p.23 Dara O Briain: School Of Cyber Security Conference p.10 Hard Sums p.15 Dara O Briain’s Science Club p.21

THE SPIEGELTENT THE TIMES CHELTENHAM LITERATURE FESTIVAL 4-13 OCTOBER Members’ booking from 26 Aug IMPERIAL GARDENS Public booking from 2 Sept

9 THE WORLD OF TECHNOLOGY

We should never underestimate the difference that technology is going to make for our children. Today, HP EVENTS AT THE FESTIVAL more than ever before, we are faced with serious challenges that we will need technology to tackle Is The Web Changing Society? p.33 – from climate change to addressing the needs of Raspberry Pi Workshops p.32 our aging populations. HP is a technology company Raspberry Pi: Imaginarium p.34 – we’ve spent 60 years developing technologies that help tackle the big issues that society faces. The Web And Us p.32 But we need everyone, not just technologists, to The Science Of The Internet p.45 understand science and technology so they can participate in the big debates about technology, its uses and abuses. That’s why we support The Times Cheltenham Science Festival – not just because PLUS, MORE TECH EVENTS… it celebrates the contribution of science and technology to our society – but because it engages How Safe Is Your Wifi? p.24 all – young and old – in the big issues of science and James Gleick: The Information p.38 technology that we will all face in the future. Coding The Game p.20 Nick Wainwright Get Hands-On In The GE Pavilion p.8 Director of European Projects, HP Labs Bristol.

CHELTENHAM CYBER SECURITY CONFERENCE 2013 New for 2013, Cheltenham Festivals is running a 1 day Cheltenham Cyber Security Conference (CCSC) during the Science Festival. CCSC 2013 gives business leaders the opportunity to get up-to- date information from some of the UK’s leading experts in the field and understand what actions organisations of all sizes can take to tackle the growing threat of cybercrime.

Visit cheltenhamfestivals.com/ccsc2013 for more information.

DON’T MISS THE CODE-BREAKING TRAILS IN THE DISCOVER ZONE AND AREA 42… Two new trails are being brought to the Festival by Cyber Security Challenge UK. Can you break the codes?

10 Box Office: 0844 880 8094 TUESDAY4JUNE cheltenhamfestivals.com/science

DEMENTIA CARE THE RISE OF DESIGNING FOR LIGHT AND TOUCHSCREEN RESISTANT BACTERIA: AND LIFE TECHNOLOGY SHOULD WE BE WORRIED? S005 Pillar Room S001 Pillar Room 3.30 – 4.30pm 11.30am – 12.30pm S003 Pillar Room £7 (£6) Members 10% off £7 (£6) Members 10% off 1.30 – 2.30pm Few things lift your mood as much A recent study showed that touchscreen £7 (£6) Members 10% off as a sunny day. Daylight improves technology, such as the iPad, can help Are you worried about the possibility of mental wellbeing, reduces jetlag to improve quality of life for people untreatable infections? Why is being sick and even eases symptoms in people living with dementia. iPads can inspire at home healthier than being in hospital? living with dementia. Neuroscientist creativity and reminiscence and also help Resistance to antibiotics is on the rise and Russell Foster and architect Ian improve communication with families in our globalised society it could become Ritchie explore how light affects our and carers, leaving a positive emotional a crisis. In a world where new antibiotic bodies and how our bodies’ needs impact. Author of the study, cognitive drugs are scarce, public health expert are influencing the design of homes, psychologist Tim Jones, and Tim Lloyd- Anthony Kessel, medical microbiologist buildings and vehicles. Yeates, founder of Alive!, a charity that Mark Wilcox and biophysicist Elspeth provides interactive activity sessions Garman explore the dangers of in care homes across the South West, antibiotic resistance and what is being explore how modern technology can done about it. improve quality of life and build bridges between generations.

MY SISTER ROSALIND FRANKLIN S002 Winton Crucible 1.30 – 2.30pm £7 (£6) Res Members 10% off The pioneering molecular biologist Rosalind Franklin’s life was cut short by ovarian cancer at the age of only 37. She is remembered now for her significant part in the discovery of the structure of DNA, the start of the greatest biological revolution of the twentieth century. But her world-famous distinguished scientific achievements started earlier, with her work on coals and carbons, and continued later, with her work on the structure of viruses. Join her sister Jenifer Glynn for this fascinating illustrated talk THE ORIGINS OF HORMONE FIGHT CLUB – drawn from the pages of her memoir SOCIETY My Sister Rosalind Franklin. S006 Winton Crucible S004 EDF Energy Arena 3.30 – 4.30pm 2 – 3pm £7 (£6) Res Members 10% off £7 (£6) Res Members 10% off From the moment you’re born to your Tim Clutton-Brock, behavioural very last breath, hormones direct your biologist and Fellow of the Royal life. They determine your health, fertility Society, explores how and why animal and even your weight. They constantly societies differ and how they affect the change as you age to meet your body’s development of males and females. Tim needs, but what challenges does this is known for his long-term, individual- present along the way? Take a whistle- based studies of mammals, including stop tour on the hormone journey with primates, red deer, Soay sheep and Anne-Lise Goddings on adolescence meerkats in the Kalahari Desert, where and hormones, Stafford Lightman his work has provided the basis for the on stress and Waljit Dhillo on how first animal docu-soap, Meerkat Manor. hormones make you fat.

ROSALIND FRANKLIN A member of the Society of Biology

Enjoy discounts and special offers all year round with Cheltenham Festivals Membership 11 Box Office: 0844 880 8094 TUESDAY4JUNE cheltenhamfestivals.com/science

SCIENCE QUESTION TIME JUST SO SCIENCE S009 Eureka Tent 4 – 5pm FREE S012 Eureka Tent Explore today’s biggest debates, newest 6 – 7pm discoveries and favourite Festival £9 (£8) Members 10% off moments with a selection of the day’s In his highly fantasised origin stories, speakers, The Times’ journalists and the Rudyard Kipling tells tales of how wild Festival team. animals have been modified from their original forms by the acts of man. But Vivienne Parry has been finding out that there are plenty of wild animals that are transforming man, or at least the medicines of man. She invites a panel of scientists to reveal the science behind some modern Just So Stories about naked mole rats, Tasmanian Devils, and pythons. You’re welcome to JAMES HONEYBORNE join us, My Best Beloved.

13 AFRICA: EYE TO EYE S007 EDF Energy Arena 4 – 5pm £7 (£6) Res Members 10% off

How do you unwind after being in ANDREA SELLA the water with 30 feeding great white sharks? How do you film a giraffe fight in super-slow motion without distracting the animals? What does STRANGE ICE a cameraman think about while an S010 Winton Crucible elephant is trying to shake him out of 5.30 – 6.30pm a tree for four hours in the night? The recent BBC series Africa has captured £7 (£6) Res Members 10% off our imagination and hearts. Join series Though you will find it in every VIVIENNE PARRY producer James Honeyborne as he refrigerator in the world, water ice is a shares behind-the-scenes stories and material so strange that it breaks almost unseen footage as they filmed the every rule in our textbooks. Chemist impossible. Andrea Sella delves into the intriguing world of ice, inspecting its properties and how it compares to other ices. Discover how it may warn of a future much less certain than we imagine... THE SECRETS OF BRAGGING ABOUT CREATIVE PEOPLE CRYSTALLOGRAPHY S013 MRC Helix Theatre S008 MRC Helix Theatre INSIDE THE 6 – 7pm 4 – 5pm CRIMINAL MIND £9 (£8) Members 10% off £7 (£6) Members 10% off DIRECTOR’S Q: How can you become more S011 Pillar Room PICK From hormones to DNA, and even how creative? A: Work with and speak drugs work in our cells, crystallography 5.30 – 6.30pm to people who are already creative! provides insight into the sheer £9 (£8) Members 10% off Computer scientists Yvonne Rogers complexity and wonder of biological Crime writers and solvers have a and Steve Benford have been structures. 100 years since the Bragg common goal: to understand criminals. travelling the world interviewing and equation that made it all possible, Author and ex-probation officer Ann working with wine-makers, dancers, Elspeth Garman and Tom Blundell Cleeves discusses how she creates her chefs and other artisans in an effort take us through the history and into the murderous villains, while James Grieve to boost their creativity. Join them future of X-ray crystallography. Celebrate takes a look at the forensic pathologist’s as they share the secrets of creative the achievements of past and present perspective as they explore what drives people and learn how you can be more scientists in the field and hear about the the criminal mind. creative too. latest advances.

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The Summerfield Lecture MAURICE SAATCHI’S MARTIN REES: MEDICAL INNOVATION SURVIVING THE BILL CENTURY S014 EDF Energy Arena S018 EDF Energy Arena 6 – 7.15pm 8.45 – 9.45pm £9 (£8) Res Members 10% off £10 (£8) Res Members 10% off After the death of his wife from ovarian Our world is getting more crowded cancer, Maurice Saatchi felt crushed MAURICE SAATCHI and interconnected, and its resources by the ‘medieval’ treatment that are under pressure. We can’t survive cancer patients must endure. It drove without powerful new technologies – him to launch a Private Member’s Bill such as biotechnology, robotics and the in the House of Lords, which seeks exploitation of space – and they offer to promote medical innovation and exciting opportunities. But what if they reduce doctors’ fear of litigation in the run out of control? The downsides could event of something going wrong. This have a global impact and even jeopardise change could save lives. But is it right humanity’s entire future. These ‘existential to give doctors license to experiment threats’ may seem unlikely, but Martin on their patients with unapproved Rees argues that it would be prudent treatments, even if they have the to pay more attention to safeguarding best of intentions? Is the distinction ourselves against them. between responsible innovation and reckless experimentation so easily made? Lord Saatchi is joined by Dame Gail Rebuck who recently lost her husband to cancer and others to MURDER MYSTERY: discuss the challenges a Bill like this WORKSHOP faces. S016 Supported by The Patrons of Cheltenham Eureka Tent Festivals 8 – 10pm £15 (£13) Members 10% off A murder has been committed at the Festival and we need crime scene investigators. Are you up to the job? With the help of forensics experts collect evidence from the scene and take it back to the lab for analysis. Lift fingerprints, examine hair and fibre samples and decipher blood spatter patterns to identify the perpetrator.

DIRECTOR’S JOCELYN BELL THE MIND OF AN BOTANY OF GIN PICK BURNELL: IN PURSUIT OLYMPIC CHAMPION OF PULSARS S019 Pillar Room S017 MRC Helix Theatre 8.45 – 10.45pm S015 Winton Crucible 8 – 9pm £25 (£23) 7.30 – 8.30pm £9 (£8) Members 10% off Includes cocktails and nibbles Over 18s only £9 (£8) Res Members 10% off The Olympics are over, medals won, As a 24-year-old PhD student Jocelyn Bell but what next for all our athletes? What Are all gins the same? Or are some Burnell made a discovery that changed techniques did they use to deal with the chemically superior to others? And what’s the way we see the Universe. The existence pressures in the run-up to and during so dry about London Dry Gin? Chemist of pulsars – dense cores of collapsed the Olympics? For those retiring how will and mixologist Noel Jackson serves up stars that emit pulsating radio waves – they cope without one of the biggest a tasty combination of science and gin in suddenly made black holes seem much challenges of their lives to plan for? Will this hands-on session. Learn how gin is more likely and provided further proof to we have another Olympics as successful made, what the Gin Act of 1736 was and Einstein’s theory of gravity. Joining us now, as 2012? Or did having a home crowd if a G&T can be considered medicinal. as a Dame and eminent astrophysicist, help increase the medal count? Sport Taste selected gins, identify the plants Jocelyn reveals the nature of pulsars and psychologist Marc Jones returns to look that give them their distinctive flavours their extreme physical properties. back at London 2012 and gives us the and discover the brands you really prefer, latest on research about enhancing sport all in the name of science! In association with IOP South West Branch performance using psychology alone. Dress to impress and book your taxi home now!

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STROKE S020 Pillar Room 12.30 – 1.30pm £7 (£6) Members 10% off One person has a stroke every 5 minutes in the UK, and those who survive are often left with devastating brain damage. Join physiologist and President and Vice-Chancellor of The University of Manchester Nancy Rothwell to find out more about strokes, their causes and how her research could revolutionise the way they are treated.

HELEN CZERSKI LIVE FROM THE ICE AGE UNIVERSE VIA JODRELL BANK S021 EDF Energy Arena 2.15 – 3.15pm S023 Winton Crucible £7 (£6) Res Members 10% off 2.30 – 3.30pm The northern hemisphere is balmy today, £7 (£6) Res Members 10% off but for most of the last 2.5 million years it When we began using telescopes was blasted by a series of ice ages. North to view our skies, the sights were America, Europe and Siberia were once astonishing. But this visible Universe is home to giant mammals - sabre tooth only part of the picture. In the 1940s, cats, ground sloths, woolly mammoths Jodrell Bank Observatory pioneered and rhinos. How did our human our exploration of the Universe using ancestors ride out the Ice Age when so radio waves instead of visible light. This DARA O BRIAIN many species perished and what does dramatically expanded our horizons history tell us about the role of glaciers – we could see quasars, pulsars and and icebergs in climate change? Join even the fading glow of the Big Bang Alice Roberts as she talks all things icy itself. With a live link to the Jodrell Bank with Operation Iceberg’s Helen Czerski Observatory, Tim O’Brien explores and archaeologist Matt Pope. modern astrophysics using real-time radio telescope observations. DARA O BRIAIN: SCHOOL OF HARD SUMS MENOPAUSE: TO HRT S025 EDF Energy Arena OR NOT TO HRT 4.15 – 5.15pm £12 (£10) Res Members 10% off S022 Pillar Room Marrying humour and science, this 2.30 – 3.30pm SCIENTIFIC IDEAS AND show is a brains against brawn contest £7 (£6) Members 10% off HUMAN DECISIONS to solve a number of intriguing The use of HRT in menopause remains puzzles. Theoretical physics graduate S024 a topic of real controversy in women’s MRC Helix Theatre Dara O Briain uses maths to find the health. Barely a week goes by without 3.45 – 4.45pm answer whilst his fellow comics, with a media report on HRT. Is it helpful? £7 (£6) Members 10% off no special aptitude for the subject, use more practical means. Show Question Harmful? Useless? What is going on and Science can tell us a lot about the world why does so much of the research seem Master Marcus du Sautoy wows us and how it works, but what we do with with fascinating facts such as how to contradict itself? Physiologist Stephen that knowledge is a very human choice – Franks and endocrinologists Saffron sheep’s ankles were man’s earliest form from decisions about medical treatments, of casino. Whitehead and Helen Buckler explore to assisted dying, to nuclear physics and the issues in menopause and the role the use of technology. Physicist Martin You can see Dara O Briain: School of for HRT. Rees and philosopher Ray Tallis debate Hard Sums on Wednesdays at 8pm from the ethical and prudential application of 1st May on Dave science. In Association with Dave A member of the Society of Biology

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HOMES THAT CUT CARBON AND COSTS S026 Winton Crucible 4.30 – 5.30pm £7 (£6) Res Members 10% off Want to save money on energy bills? Want to cut your home’s carbon emissions? Join Jonathon Porritt as he talks to people at the cutting-edge of cutting costs and emissions in both new and old homes. Jonathan Hines is an expert in the Passive House movement, LUCY WORSLEY the gold standard in efficiency; Bill Dunster is the architect behind London’s zero energy development; and Adrian Phillips describes how existing houses in Cheltenham have been retrofitted to improve their energy efficiency. DONOR CONCEPTION: A PRIVATE FAMILY FIT TO RULE: HOW MATTER? ROYAL ILLNESS CHANGED HISTORY S028 Eureka Tent 5 – 6pm S030 EDF Energy Arena £7 (£6) Members 10% off 6.15 – 7.15pm £10 (£8) Res Members 10% off In 2009, 1,756 children were born in the UK following donation of eggs or The Royal Family is, and always has been, a sperm. Should these children be told fascination of the British people (especially how they were conceived? If so, how? as we all wait for the arrival of the newest And by whom? What rights do donors Royal baby). But how much do we really have in learning about children they know about our past monarchs? Lucy have helped create? Join sociologist Worsley, Chief Curator at Historic Royal Tabitha Freeman, egg donor and Palaces and presenter of BBC2’s Fit to Rule is CEO of the National Gamete Donation joined by Wellcome Trust medical historian Trust Laura Witjens and Professor of Elizabeth Hurren and BBC Commissioning IS IT A BOY OR A Social Work Eric Blyth as they discuss Editor for History Martin Davidson to the big ethical questions about donor uncover some of the frailties and biological GIRL? conceptions. weaknesses of our previous Royal Families S027 Pillar Room and reveal the truth behind some age old mysterious Royal deaths… 4.30 – 5.30pm £7 (£6) Members 10% off What makes boys boys and girls girls? Is everyone a boy or a girl? These questions are difficult to answer, especially since sex and gender are MEAT AND POTATOES SOLAR SUPERSTORMS: not the same thing. Hormones play a OR TWO VEG? GLOBAL THREAT OR pivotal role in determining how our STORM IN A TEA CUP? sex develops both in and out of the S029 MRC Helix Theatre womb. But how we feel about our 6.15 – 7.15pm S031 Pillar Room gender is influenced by our sex, society £9 (£8) Members 10% off 6.30 – 7.30pm and culture. Anatomist and presenter £9 (£8) Members 10% off Alice Roberts, paediatric psychologist Science has shown that our love Polly Carmichael and others discuss of meat is contributing to carbon Our lives revolve around technology. But what decides your gender – hormones, emissions and climate change. But this reliance means we are at the mercy of anatomy, society or all three? how many of us are taking this phenomena like space weather which can seriously? Do we need to change the disrupt satellites, power supplies, air travel amount of meat we consume? Will and other technologies. How much should it take a change in policy to force us we worry about this? Could it ever cause a to cut back or are there other ways catastrophic electronic black out? And how to get us to rethink? Tim Lang, Tara can we protect ourselves against its effects? Garnett and Richard Twine consider Solar scientist Lucie Green is joined by the carnivore’s dilemma. Fellow of the Royal Academy of Engineering Paul Cannon to explore space weather and its impact on our daily lives.

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SCIENCE QUESTION TIME S032 Eureka Tent 7 – 8pm FREE Explore today’s biggest debates, newest discoveries and favourite Festival moments with a selection of the day’s speakers, The Times’ journalists and the Festival team.

THE FUTURE OF BRITAIN’S FORESTS S033 MRC Helix Theatre 8.15 – 9.15pm £9 (£8) Members 10% off The British Isles are great for tree growth thanks to mild winters, plentiful rainfall and fertile soil. But the future of Britain’s trees could be in jeopardy. Pressures from tree disease and insect damage, climate change and tree farming practices are DO YOU JUDGE A BOOK BADGER CULLING: all taking their toll on our forests. Joan Webber and Daniel Bebber discuss BY ITS COVER? THE DEBATE what is happening and what can be done S035 Pillar Room DIRECTOR’S S036 Winton Crucible to save the future of British forests. 8.30 – 9.30pm PICK 8.30 – 9.45pm

£9 (£8) Members 10% off £10 (£8) Res Members 10% off Join us as we take a close look at the The motion: This House believes business of book marketing from the that badger culling will decrease the A member of the Society of Biology (often vexed) process of designing and occurrence of bovine TB. approving a jacket, to its final position June sees the start of the badger cull on the shelves of your local bookstore. pilot in Gloucestershire and Somerset James Daunt, Chief Executive of high but it faces great opposition. How do DIRECTOR’S street retailer Waterstones, and Claire PICK we balance the needs of badgers and Ward, Creative Director of Transworld farmers? For the motion are vet Roger Publishers, offer their unique insights Blowey and farmer Phil Latham and into the book business while Professor against are vet Elizabeth Mullineaux of Neuroscience Barbara Sahakian and ex-farmer Pauline Kidner. provides insights into the decision Chaired by Jonathon Porritt. making process to see if we choose books with our hearts or with our minds. PETER HIGGS THE WAR ON VIRUSES 13 S037 Eureka Tent 9 –10pm PETER HIGGS IN £9 (£8) Members 10% off CONVERSATION WITH Is it worth being vaccinated? Or are we DARA O BRIAIN causing viruses to become smarter and S034 EDF Energy Arena more insidious? Epidemiologist Katrina Lythgoe delves into the virus vortex 8.30 – 9.30pm WED 5 JUNE to show how humans are driving their £15 (£13) Res Members 10% off It’s not what you do, it’s the way that you do it evolution. With a live simulated infection Meet Peter Higgs, the man behind the to show how viruses spread, this is one Many businesses have started on the Higgs boson, as he talks to Dara O Briain bug you will want to catch! journey to being more sustainable, but about his life and work – where the are they being as effective as possible? inspiration came from and how he feels about the recent discovery of a Higgs- Cheltenham Science Festival is proud to be partnering with Commercial Group for its like-boson in CERN. seventh CSR day programme, providing the perfect platform for sharing best practice and innovative ideas to reinvigorate Sustainability initiatives within business. See csrday.co.uk for more information.

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WATER: IT’S ALL THAT SLEEPLESS IN MATTERS CHELTENHAM S038 Pillar Room S043 Winton Crucible 11.30am – 12.30pm 4 – 5pm £7 (£6) Members 10% off £8 (£7) Res Members 10% off One person uses an average of 150 litres We all need a good forty winks. But for of water per day. But unlike the ever- many people, this is just a dream. The increasing global population, the amount reality is a nightmare of disturbed sleep of water on Earth remains the same. With brought on by a variety of disorders. some regions already drought-stricken, Sleep clinician Kirstie Anderson talks how can we ensure there is enough to about the conditions that keep Britain go around? Environmental engineer up at night, while respiratory consultant Paul Younger explores the science and JAMES WATSON John Stradling looks at how one of the politics of our most precious resource. commonest conditions, sleep apnoea, For the last fifty years, wars have been impacts our overall health, with Russell fought over oil; for the next fifty, will they Foster in the chair to keep us all awake. be fought over water?

DIRECTOR’S PICK LIQUID CRYSTALS: The Times Interview FROM BUTTERFLIES JAMES WATSON IN TO iPADS CONVERSATION WITH MATT RIDLEY S039 Pillar Room 1.30 – 2.30pm S041 EDF Energy Arena £7 (£6) Members 10% off 2 – 3pm Liquid crystals were once the curious £15 (£13) Res Members 10% off property of a simple molecule from a In the year that marks the 60th carrot, with no apparent use; now they anniversary of the discovery of the support a multi-billion pound industry. structure of DNA, James Watson, the Stephen Kelly explores the beauty, man responsible for that momentous history and evolution of liquid crystals, discovery with Francis Crick, joins Matt from the iridescence of a butterfly wing Ridley to discuss his life and latest work. through the very first digital watches and calculators to the latest iPads, LCD screens and mobile phones.

THE TRUTH ABOUT FLU? S042 Pillar Room THE HIGGS BOSON: EXOPLANET 3.30 – 4.30pm FROM THEORY TO EXPLORERS £7 (£6) Members 10% off REALITY S040 Winton Crucible Does being on public transport increase S044 EDF Energy Arena 2 – 3pm your chances of catching flu? Does ‘man 4 – 5.15pm £7 (£6) Res Members 10% off flu’ actually exist? Do pets make you healthier? Discover what the recent UK £10 (£8) Res Members 10% off Thousands of planets outside our solar Flusurvey reveals about the myths and 2012 was a monumental year in particle system have been discovered since the truths of flu and how best to avoid its physics. Almost 50 years after its first in 1995, but what are these other clutches, with flu researchers Alma Adler existence was first predicted the elusive worlds like, and could any of them and Ken Eames from the London School Higgs boson – or something a lot like sustain life? Exoplanet investigator of Hygiene & Tropical Medicine along it – was detected at the Large Hadron and Royal Society University Research with doctor Dawn Harper. Collider. Peter Higgs is joined by CERN Fellow Giovanni Tinetti joins Director for Research Sergio Bertolucci astrobiologist Paul Davies and David The Flusurvey is a Europe-wide project, and experimental physicist Tara Shears Acreman, who uses Met Office models started during the swine flu epidemic in to discuss how his theory is becoming to predict climate on exoplanets, 2009. It aims to understand how flu spreads reality and what the discovery means for to explore the possibilities of these by gathering data directly from members CERN and particle physics as a whole. exciting discoveries. of the public.

Join the survey at flusurvey.org.uk

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DIABETES, HEART ATTACKS AND FLU S045 MRC Helix Theatre 4.45 – 5.45pm £7 (£6) Members 10% off There is growing evidence of a link between catching flu and your chances of developing diabetes. On the bright side, however, people who receive flu jabs are half as likely to have heart attacks. Join leading researchers Tom Jefferson and John Oxford as they uncover some of the lesser known facts about flu and discuss our attitudes towards hand washing, handshakes and vaccinations.

THE SCIENCE AND ART FAMELAB OF PATIENT CARE INTERNATIONAL SEMI-FINAL S048 Pillar Room 5.30 – 6.45pm Winton Crucible £8 (£7) Members 10% off S050 6.45 – 8.15pm Good medicine goes far beyond S051 9 – 10.30pm science: trust, ethical judgment, patient £6 (£5) Res Members 10% off dignity and care are as important as The world’s greatest international the technical treatment of disease. competition returns! In just three In the light of the Francis report into minutes, the finalists excite and WHEN DISASTER failings at mid-Staffs hospital,Sean entertain you with the latest in science Elyan, Medical Director at Cheltenham and engineering, and with only the STRIKES General Hospital; Jocelyn Cornwell of props they can carry on stage! Quentin The Point of Care Foundation and the S046 Cooper introduces finalists from over 20 Parabola Arts Centre King’s Fund; philosopher Ray Tallis; 5 – 6pm countries as they battle it out for a place and poet Jo Shapcott come together in the FameLab International Final. £8 (£7) Res Members 10% off to discuss the science, art, morality After an earthquake or tsunami, the and politics of medicine. Chaired by urge to help is very strong. No wonder Consultant Oncologist and Curator of medical teams fly in to do whatever Medicine Unboxed, Sam Guglani. they can. But sometimes their attempts In association with Medicine Unboxed to help can make things worse. Hear www.medicineunboxed.com surprising perspectives from those who FLY-SIZED SPIES have worked in emergency relief: Tony Redmond, Lead for Global Health at the S052 MRC Helix Theatre Manchester Academic Health Sciences CODING THE GAME 6.45 – 7.45pm Centre, University of Manchester; former £9 (£8) Members 10% off Director General of Army Medical S049 EDF Energy Arena Services Major General Alan Hawley; and 6.15 – 7.15pm Insect-sized surveillance robots will soon be on the move. Swarms of them Rony Brauman, who was president of £10 (£8) Res Members 10% off Médecins Sans Frontières for 15 years. could be used by the military for covert From the ‘bedroom coders’ of the 80s surveillance or by humanitarian outfits to to the studios behind many of today’s find natural disaster survivors.Richard most popular international video games, Bomphrey, a biologist whose work the UK has always been at the forefront on insect wing design can be of great of games development. Dara O Briain importance to the miniature machines joins Alex McLean, a 20-year games of the future, is joined by Airbus wing SCIENCE QUESTION TIME industry veteran most recently CTO at designer Norman Wood to explain how Codemasters and former head of their the technology from these miniature S047 Eureka Tent Bafta winning F1 Birmingham Studio, and marvels could apply to human-sized 5 – 6pm FREE others, to get into the detail of what’s aircraft. Explore today’s biggest debates, newest involved in making modern video games. discoveries and favourite Festival moments with a selection of the day’s speakers, The Times’ journalists and the Festival team.

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GENES, CELLS AND SCIENCE, THE BRAINS: PROMISES OF ECONOMY AND YOU THE NEW BIOLOGY DARA O BRIAIN’S SCIENCE CLUB S057 Pillar Room S053 Eureka Tent 8.45 – 9.45pm 7 – 8pm S055 EDF Energy Arena £9 (£8) Members 10% off 8.30 – 9.30pm £9 (£8) Members 10% off These are times of austerity, yet the £15 (£13) Res Members 10% off The human genome project, DNA biobanks, Government has repeatedly shown a stem cell research and the brain sciences all Dara O Briain invites you to join his commitment to funding for science, once made extravagant claims: we’ll cure Science Club. With a crack team of engineering and technology. Why? Can diseases like cancer and schizophrenia; we experts – including Mark Miodownik, investment in these areas really help can explain who we are using DNA and Helen Czerski and Alok Jha – he our economy out of the doldrums? nerve cells. Where is the new world we were brings us the very latest, astonishing Will it be enough to maintain the UK’s promised? Feminist sociologist Hilary Rose science that will transform our lives, international profile in science, as well and neuroscientist Steven Rose deconstruct our future and our understanding of as having an impact at local level? Guest these extravagant claims by dissecting both the universe! The weird and wonderful Director David Willetts, Jim Al-Khalili the science and the political economy of worlds of music, extinction and space and guests discuss science, the economy these vast projects. featured in the first series. What will and its impact on you. they investigate here? Check cheltenhamfestivals.com to find out.

A member of the Society of Biology STEM CELLS AND SAFER MEDICINES S058 Eureka Tent 9 – 10pm £9 (£8) Members 10% off Only 1 in 5,000 potential new drugs reaches the market. Many fail in trials or are withdrawn because serious side effects are not spotted early. About 45% of drug withdrawals are down to toxic effects on the heart, a common cause of clinical trial failures. It puts patient safety at risk and costs pharmaceutical companies billions. But what if we could avoid these problems? Stephen Minger discusses how using human heart and liver cells grown from stem cells could provide more reliable testing of new medicines.

THE COLOUR OF MUSIC THE SCIENTIST AND THE LANDSCAPE S054 Parabola Arts Centre 7.30 – 9pm DESIGNER £12 (£10) Res Members 10% off S056 MRC Helix Theatre Artist Philippa Stanton has synaesthesia, 8.45 – 9.45pm meaning she ‘sees’ sounds as she hears £9 (£8) Members 10% off them. In this special event, watch as Renowned landscape architect pianist Alex Wilson performs Mussorgsky’s and designer Charles Jencks finds Pictures at an Exhibition, with Philippa inspiration in the patterns of nature painting the shapes and colours that she and science. His latest work is a sees while listening to the music. They sculpture of RNA, the sister molecule will be joined by neuroscientist Jamie to DNA, which was unveiled by Ward, who will explain how the senses of James Watson in April this year at people with synaesthesia cause them to Dublin’s National Botanic Garden. experience the world in a unique way. Here, the scientist and the landscape designer share their passion for science and art, and the points of Messier-Bugatti-Dowty intersection between them where beautiful and meaningful things can happen.

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Find out how our research has had a lasting influence on healthcare and wellbeing in the UK and globally at our centenary website: www.centenary.mrc.ac.uk

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SCIENCE FROM BENEATH THE SEA S059 MRC Helix Theatre 10.15 – 11.15am £7 (£6) Members 10% off What could organisms from the sea offer? Sunscreen from corals? Medicine from sponges? Chemists Paul Long and Marcel Jaspars explore what we could make from under the sea, with biologist Helen Scales who asks why keeping our oceans healthy is so important. There is plenty more than just fish in the sea!

WILL HUMANS EVOLVE THE EIGHT GREAT IN THE FUTURE? TECHNOLOGIES: HOW S062 EDF Energy Arena BRITAIN LEADS THE 12 – 1pm WORLD £8 (£7) Res Members 10% off S060 Pillar Room 5 million years of evolutionary challenges 10.45 – 11.45am have made us into Homo sapiens, but £7 (£6) Members 10% off how might our physiology evolve in the future as we face new challenges like Did you know that a modern tomato climate change? Could we adapt to live is as sophisticated as an iPhone? Will in extreme environments – even space Britain’s engine technology create – if we need to? Mark Thomas, Damian the first genuinely reusable space Bailey and David Green explore where plane? When will we 3D print the first we have come from, the importance of aeroplane? Join David Willetts to cultural evolution and where we may be explore examples of the eight great heading in the future. technologies – from synthetic biology to advanced materials – that will drive In association with EHBEA BUMPOLOGY: Britain into Tomorrow’s World. THE TRUTH ABOUT PREGNANCY S064 Pillar Room A member of the Society of Biology 1.15 – 2.15pm £8 (£7) Members 10% off Farming for the Is the age of silicon How much alcohol is really safe in Future? over? pregnancy? Will the shape of my bump tell me the sex of my child? Can eating S061 S063 The Queen’s Hotel MRC Helix Theatre curry make the new baby prefer curry 12 – 2pm 12.15 –1.15pm later? Pregnancy provokes moments of £5 (contribution to a light lunch) £8 (£7) Members 10% off wonder and a stream of contradictory How will we feed the estimated nine In 100 years’ time silicon chips will look advice. For New Scientist’s Linda billion people on the planet by 2050? retro, replaced by new and smarter Geddes, pregnancy inspired a personal How will this impact on the environment materials. What will be the next big quest for intelligent answers. She is and the UK agricultural sector? This thing? Colin Humphreys champions joined by Tracey Brown from Sense Sciencewise session – hosted by Science gallium nitride, which beats silicon About Science and Vivette Glover Minister, David Willetts – is your in cost, size, weight, efficiency and from the Fetal and Neonatal Research chance to let the Government know power; Neil Alford makes the case for Group at Imperial College London. what you think about using science and graphene, with which we can make Chaired by Alice Roberts. technology to increase food production bendable electronic gadgets; and and make farming more sustainable. The Nikolay Zheludev picks up the baton discussions will feed directly into the for metamaterials and nanophotonics, future implementation of the UK’s new where light replaces electrical signals agri-tech strategy. altogether. Could Silicon Valley be headed for a name change?

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QUANTUM BIOLOGY HOW SAFE IS YOUR WIFI? S065 EDF Energy Arena 2 – 3pm S069 Winton Crucible £8 (£7) Res Members 10% off 4 – 5pm The strange theory of quantum £8 (£7) Res Members 10% off mechanics – where tiny particles behave James Lyne, Director of Technology in extraordinary, counter-intuitive ways – Strategy at anti-virus company Sophos, is fundamental to chemistry and physics has been putting Cheltenham’s wireless but could it also help answer some of the security to the test. Over 200,000 new great questions in the biological world? variants of malicious code are seen Jim Al-Khalili, Johnjoe McFadden, KEVIN FONG every day, each of them designed to Alexandra Olaya-Castro and Paul steal your data, your money and invade Davies discuss the emerging field of your privacy. With cybercrime being quantum biology and the role it can play such big business nowadays, how safe in our understanding of the natural world, INTENSIVE CARE is your WiFi? James demonstrates some from photosynthesis to bird navigation to WITH KEVIN FONG innovative ways your data gets hacked, evolution and the origins of life. how to avoid it and reveals how secure S067 MRC Helix Theatre Cheltenham’s networks really are... 2.15 – 3.15pm £8 (£7) Members 10% off If an accident or illness causes you to stop breathing and your organs to fail, your best chance of survival is in an intensive care unit. But how do doctors keep critically ill patients alive? Celebrating the 60th anniversary of intensive care medicine, doctor Kevin Fong and a panel of his colleagues share their unique experiences.

JIM AL-KHALILI REGENERATIVE MEDICINE: WHERE PARTICLE PHYSICS: WILL WE BE IN 50 AN INTRODUCTION YEARS? S070 EDF Energy Arena 4 – 5pm S068 Pillar Room £8 (£7) Res Members 10% off 3.30 – 4.30pm £8 (£7) Members 10% off Particle physicists Tom Whyntie and Mike Charlton give a whirlwind OF MICE AND MEN Regenerative medicine has come a long introduction to particle physics, way in the last thirty years, from the first covering 100 years’ worth of science S066 Winton Crucible isolation of embryonic stem cells in the in just one hour. From electrons and 2 – 3pm eighties to the first human windpipe Crookes tubes to trapped antimatter, reconstruction in 2012. What lies in store £8 (£7) Res Members 10% off the Higgs boson and the Large Hadron in the next fifty years? Will we see an end Collider, come along and find out what Why are animals so important to to organ donor shortages, or be able you (and everything else in the world) scientific research? It’s an issue that to regenerate whole limbs? Pioneering are made of. Beginners welcome. causes considerable ethical debate, yet surgeon Martin Birchall and plastic the reality of animal research remains and reconstructive surgeon Felicity out of sight of the wider public. Not any Mehendale discuss what the future longer. With pictures and video from might hold for this exciting branch of the mouse house at a research facility in medicine. Oxfordshire, biologist Adam Rutherford and researcher Steve Brown explore the debate and examine whether media SCIENCE QUESTION TIME reports match the reality of animal research. S071 MRC Helix Theatre 4.30 – 5.30pm FREE Explore today’s biggest debates, newest discoveries and favourite Festival moments with a selection of the day’s speakers, The Times’ journalists and the Festival team.

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CAN WE TRUST CLIMATE MODELS? AUTONOMOUS ROBOTS S072 Pillar Room 5.45 – 6.45pm S077 Parabola Arts Centre £8 (£7) Members 10% off 6.30 – 7.30pm £10 (£8) Res Members 10% off Computer-generated models are used to predict future climates, but how much From self-driving cars to rovers on faith should we put in them to guide MICHAEL BERKELEY Mars, we need our robots to have future actions? Should we treat their enough autonomy to get from A to predictions as fact or fiction? With the hot B. Even in the home, robots won’t be topic of climate change ever current, can bringing us tea in bed until they can we wait to find out? Join climate scientist MICHAEL BERKELEY: find the milk in the fridge and get Tamsin Edwards, sceptic Jonathan HEARING IN A upstairs without tripping over the Jones and policy adviser Claire Craig. CREATIVE WORLD dog. Meet some engineers working Temperatures could rise in this session… on autonomous robots: Alan Winfield S075 MRC Helix Theatre of Bristol Robotics Laboratory with 6.30 – 7.30pm a handful of swarming robots; Nick Hawes of Birmingham University £10 (£8) Members 10% off Cabot Institute with his robot Dora the Explorer; In association with ice2sea Radio 3 presenter Michael Berkeley has and Abigail Hutty of Astrium with a been composing music since he was six. prototype for the next Mars rover. His whole life has revolved around music. The Kavli Prize Laureate Lecture But then, two years ago, an ordinary cold THE KUIPER BELTT virusv triggered a catastrophic loss of hearing. He joins Owen Brimijoin from S073 Winton Crucible DIRECTOR’S tthe Scottish section of the MRC Institute PICK 6 – 7pm of Hearing Research to describe how £10 (£8) Res Members 10% offoff he came to terms with his deafness and discover how the brain compensates for Beyond the orbit of Neptune in the the loss of one of its vital senses. deep dark depths of our Solar System There will be a BSL interpreter in this event. lies the Kuiper Belt, home of the former planet Pluto and billions of other objects made of dust and ice. The discovery and exploration of the belt earned astronomers David Jewitt, from UCLA in California, and Jane Luu, from MIT in Boston, the prestigious Kavli Prize for DIRECTOR’S astrophysics. They join Adam Rutherford PICK to discuss their work and what it has revealed about the formation and evolution of the Solar System.

QUENTIN COOPER

VIRUS ATTACKS FROM THE SKY FAMELAB WHO HOLDS THE INTERNATIONAL FINAL SCALPEL? S074 Eureka Tent S076 6.30 – 7.30pm EDF Energy Arena S078 ExperiTent 6.30 – 8pm £8 (£7) Members 10% off 7.30 – 8.30pm £10 (£8) Res Members 10% off £10 (£8) Members 10% off Midges and mosquitoes are spreading viruses to where they have never been They’ve enthralled audiences. They’ve Surgeons have to practice, but should it before, including Britain. But why? What fought for their place. Now, with an be on us? Professor of Surgical Education are the consequences? What will arrive arsenal of charm, personality and Roger Kneebone and his team explore next? Virologist Peter Mertens discusses scientific expertise, the remaining 10 the ethics of this cutting edge area. With what impact these viral diseases have, contestants each deliver three minutes video footage of actual surgery, see the entomologist Simon Carpenter looks of science in style and compete to be subtle ways in which master surgeons at what pests are bringing them to our crowned the FameLab International pass on their craft and the challenges shores and geneticist Mark Fife explains winner 2013. Join Quentin Cooper for that they face in training. how genomics can help control the the biggest FameLab competition. Who damage now and in the future, with John will you cheer on? Fazakerley in the chair.

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ENERGY HARVESTING GREAT COMETS DIRECTOR’S S079 Eureka Tent S081 MRC Helix Theatre PICK 8.30 – 9.30pm 8.30 – 9.30pm £10 (£8) Members 10% off £10 (£8) Members 10% off What if your phone could be charged Great Comets are exceptionally bright, by walking? Energy harvesting devices meaning we can see them with the are scavengers, capturing energy that naked eye when they hurtle through would otherwise be wasted and storing our skies. Normally we see Great Comets it for future use. Vibration from engines, about once per decade but, in 2013, two temperature gradients and even blood will be visible. Join astronomers Alan sugar can all generate enough energy Fitzsimmons, David Jewitt and Pete to power electronic devices. Engineers Lawrence for a sparkling insight into Paul Mitcheson and Geoff Merrett are these icy rocks from outer space with tips DIRECTOR’S working in this exciting field, as is heart on how best to spot them. PICK surgeon Sukumaran Nair, who is looking at ways that energy harvesting might be used to keep artificial hearts pumping.

PRIDE, PREJUDICE

THE UGLY ANIMAL AND THE DOCTOR PRESERVATION S083 Parabola Arts Centre SOCIETY 8.30 – 9.30pm £10 (£8) Res Members 10% off S082 Winton Crucible 8.30 – 10pm Pride and Prejudice is one of the best- £10 (£8) Res Members 10% off loved novels of all time and celebrates its 200th anniversary this year. But The panda gets too much attention. how much were Jane Austen’s plots The Ugly Animal Preservation Society is and characters influenced and shaped dedicated to raising the profile of Mother by the views – and prejudices – of the Nature’s more aesthetically challenged medical men and theories of her day? children. But the Society needs a Vivienne Parry is joined by Austen mascot, a creature to rival the cute and expert Janet Todd and medical cuddly emblems of many charities and historian Michael Worboys to discuss organisations. Join Simon Watt and how scientific thinking in the Regency friends as they each champion a different period influenced attitudes towards, ugly endangered species. Vote for what amongst other things, health, sex, will become the Society’s symbol in a childbirth and women. comedy night with a conservation twist!

ENERGY SCIENCE OF TEA 13 S084 EDF Energy Arena S080 Pillar Room 9 – 10pm 8.30 – 10pm £10 (£8) Res Members 10% off £12 (£10) Energy seems such a fundamental STARGAZING Milk first or after? Paper or china? concept and yet is so hard to describe, Health drink or caffeine high? We all with biologists, chemists and physicists S085 MRC Helix Theatre love a good cuppa and this is your each seeming to have their own 10pm – Late FREE chance to learn about the chemistry definition. So what is energy? How do we and pharmacology behind the perfect make and collect it, and how do we use Join the Cotswold Astronomical Society brew. Taste your way through a myriad it? Join Jim Al-Khalili in an event that will for an evening of stargazing, including of teas with an expert tea-taster from sort out your matter from your antimatter, an introduction to advances in telescope Taylor’s of Harrogate and avid tea- your potential from your magnetic and observing, a chance to observe the drinking scientists Clive Page, Andrea your thermal from your radiant and take heavens for yourself and the possibility of Sella and Mark Miodownik. you back to the basics of energy. seeing Saturn’s rings.

DIRECTOR’S A member of the Society of Biology PICK

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We’re all diff erent. We like diff erent things and we read the news in diff erent ways. So our subscription packs are designed to fi t your life. Why not discover which one suits you? Visit timespacks.com/ fi ndtherightpack or call one of our experts on 0800 001 4254 and quote ‘Recommend8’. After a few questions we’ll identify the pack that’s perfect for you. PLAN YOUR PERFECT FESTIVAL 10am 11am 12noon 1pm 2pm 3pm 4p TUESDAY 4 JUNE S001 DEMENTIA CARE AND S003 THE RISE OF S005 DESIGNI PILLAR TOUCHSCREEN TECHNOLOGY RESISTANT BACTERIA LIGHT AND S004 THE ORIGINS ARENA OF SOCIETY S S002 MY SISTER ROSALIND CRUCIBLE FRANKLIN S006 HORMONE F HELIX S EUREKA WEDNESDAY 5 JUNE S022 MENOPAUSE: TO HRT PILLAR S020 STROKE OR NOT TO HRT? ARENA S021 ICE AGE S023 LIVE FROM THE CRUCIBLE UNIVERSE VIA JODRELL BANK S024 SCIE HELIX HUMA EUREKA THURSDAY 6 JUNE S038 WATER: IT’S ALL THAT S039 LIQUID CRYSTALS: FROM PILLAR MATTERS BUTTERFLIES TO iPADS S042 THE TRUTH A S041 JAMES WATSON ARENA AND MATT RIDLEY CRUCIBLE S040 EXOPLANET EXPLORERS HELIX EUREKA PAC FRIDAY 7 JUNE S060 THE EIGHT GREAT S064 BUMPOLOGY: THE S068 REGENE PILLAR TECHNOLOGIES TRUTH ABOUT PREGNANCY MEDICIN S062 WILL HUMANS EVOLVE S ARENA IN THE FUTURE? S065 QUANTUM BIOLOGY CRUCIBLE S066 OF MICE AND MEN S059 SCIENCE FROM S063 IS THE AGE OF SILICON S067 INTENSIVE CARE HELIX BENEATH THE SEA OVER? WITH KEVIN FONG EUREKA PAC QUEEN’S S061 FARMING FOR THE FUTURE? X-TENT SATURDAY 8 JUNE S092 CONTROLLING THE MIND AND PILLAR SLICING THE BODY WITH LIGHT S099 THE WEB AND US S104 AGEING FAST AND SLOW S100 BANG GOES THE ARENA SF07 TALON-SPOTTING S097 HORIZON FIREWORK SF08 STEFAN GATES AND CRUCIBLE ANDREA SELLA SF10 PERIODIC SUCCESS S102 THE HAZARDS OF LIFE S098 IS MY IMMUNE SYSTEM HELIX S089 FLEXIBLE INHERITANCE NORMAL? S101 HAPPY BIRTHDAY MRC SF03 CRIME SCENE SF04 CRIME SCENE SF05 CRIME SCENE SF06 CRIME SCENE EUREKA INVESTIGATION INVESTIGATION INVESTIGATION INVESTIGATION SEC S086-087 INTRICATE OPERATIONS / S090-091 NO MORE SCALPELS? / S095-096 EMERGENCY TRAUMA (CHECK LISTING FOR EXACT TIMES) S088 CLIMATE: A VERY SF09 DAREDEVIL LABS: S103 ALBERT EINSTEIN: PAC SHORT INTRODUCTION EVEREST RELATIVITIVELY SPEAKING SA S093 RASPBERRY Pi WORKSHOP S094 RASPBERRY Pi WORKSHOP CLC SF11 FIRE: FRIEND OR FOE? SUNDAY 9 JUNE S126 PAIN: WHY DOES IT S131 THE AGEING IMMUNE S133 CALL MY GENETICALLY PILLAR HURT SO MUCH? SYSTEM ENGINEERED BLUFF S132 JAMES GLEICK: THE S1 ARENA SF17 TSUNAMI SURVIVAL S129 A DOG NOSE BEST INFORMATION SF18 SCIENCE SF20 DO YOU SEE CRUCIBLE S121 ANIMAL DIARIES MISADVENTURES WHAT I SEE? S123 MIND CONTROLLING S130 BRAIN ENHANCING SF19 THE BIG BOOK OF HELIX MICROBES DRUGS: WOULD YOU? NATURAL HISTORY EUREKA SF13 DINOSAUR DIG SF14 DINOSAUR DIG SF15 DINOSAUR DIG SF16 DINOSAUR DIG SEC S119-120 INTRICATE OPERATIONS / S124-125 NO MORE SCALPELS? / S127-128 EMERGENCY TRAUMA (CHECK LISTING FOR EXACT TIMES) X-TENT 10am 11am 12noon 1pm 2pm 3pm 4p

28 VENUES ARENA = EDF ENERGY ARENA CRUCIBLE = WINTON CRUCIBLE EUREKA = EUREKA TENT X-TENT = EXPERITENT PILLAR = TOWN HALL PILLAR ROOM PAC = PARABOLA ARTS CENTRE SEC = Box Office: 0844 880 8094 cheltenhamfestivals.com/science

4pm 5pm 6pm 7pm 8pm 9pm 10pm

DESIGNING FOR S011 INSIDE THE GHT AND LIFE CRIMINAL MIND S019 BOTANY OF GIN S014 MAURICE SAATCHI’S MEDICAL S018 MARTIN REES: S007 AFRICA: EYE TO EYE INNOVATION BILL SURVIVING THE CENTURY S015 JOCELYN BELL BURNELL: RMONE FIGHT CLUB S010 STRANGE ICE IN PURSUIT OF PULSARS S008 BRAGGING ABOUT S013 THE SECRETS OF S017 THE MIND OF AN CRYSTALLOGRAPHY CREATIVE PEOPLE OLYMPIC CHAMPION S009 SCIENCE QUESTION TIME S012 JUST SO SCIENCE S016 MURDER MYSTERY

S035 DO YOU JUDGE A BOOK S027 IS IT A BOY OR A GIRL? S031 SOLAR SUPERSTORMS BY ITS COVER? S025 DARA O BRIAIN: S030 FIT TO RULE: HOW ROYAL S034 PETER HIGGS AND SCHOOL OF HARD SUMS ILLNESS CHANGED HISTORY DARA O BRIAIN S026 HOMES THAT CUT CARBON AND COSTS SF01 AS IF BY MAGIC S036 BADGER CULLING: THE DEBATE 024 SCIENTIFIC IDEAS AND S029 MEAT AND POTATOES S033 THE FUTURE OF HUMAN DECISIONS OR TWO VEG? BRITAIN’S FORESTS S028 DONOR CONCEPTION: S032 SCIENCE A PRIVATE FAMILY MATTER? QUESTION TIME S037 THE WAR ON VIRUSES

S048 THE SCIENCE AND ART OF S057 SCIENCE, THE ECONOMY TRUTH ABOUT FLU? PATIENT CARE AND YOU S044 THE HIGGS BOSON: S055 DARA O BRIAIN’S FROM THEORY TO REALITY S049 CODING THE GAME SCIENCE CLUB S043 SLEEPLESS IN CHELTENHAM S050 FAMELAB INTERNATIONAL SEMI-FINAL S051 FAMELAB INTERNATIONAL SEMI-FINAL S045 DIABETES, HEART ATTACKS S056 THE SCIENTIST AND AND FLU S052 FLY-SIZED SPIES THE LANDSCAPE DESIGNER S047 SCIENCE S053 GENES, CELLS S058 STEM CELLS AND QUESTION TIME AND BRAINS SAFER MEDICINES S046 WHEN DISASTER STRIKES S054 THE COLOUR OF MUSIC

REGENERATIVE S072 CAN WE TRUST CLIMATE MEDICINE MODELS? S080 SCIENCE OF TEA S070 PARTICLE PHYSICS: AN INTRODUCTION S076 FAMELAB INTERNATIONAL FINAL S084 ENERGY S069 HOW SAFE IS S082 THE UGLY ANIMAL PRESERVATION YOUR WIFI? S073 THE KUIPER BELT SOCIETY S071 SCIENCE S085 QUESTION TIME S075 MICHAEL BERKELEY S081 GREAT COMETS STARGAZING S074 VIRUS ATTACKS FROM THE SKY S079 ENERGY HARVESTING S083 PRIDE, PREJUDICE S077 AUTONOMOUS ROBOTS AND THE DOCTOR

S078 WHO HOLDS THE SF02 WORLD OF SURGERY SCALPEL?

S109 THINKING WITHOUT LOW WORDS: THE TANGO S115 SCIENCE BURLESQUE S105 ANATOMY SCAN: LIVE S112 BIRDWATCHING S117 STAND-UP MATHS 2013 S108 THINKING WITHOUT S113 MICHAEL MOSLEY: S118 WHAT MAKES INSECTS WORDS THE FAST DIET TICK? SF12 EXTREME SPORTS IN S111 RASPBERRY Pi: SPACE IMAGINARIUM S114 EXTREMES S106 DRAW YOUR ALLERGY

S107 IS THE WEB CHANGING SOCIETY? S110 THE LIFE OF BRAIN S116 SHAKESPEARE’S MEDICINE CABINET

OE?

LLY S144 LAB NOTES: SONGS S137 LANDGRABBERS FROM SCIENCE S134 MARS CURIOSITY: THE S138 RISE OF THE NASA ROVER CONTINENTS S135 ARE YOUR MAGISTERIA S140 THE OVER-AMBITIOUS DEMO OVERLAPPING? CHALLENGE 2013 SF21 THE SCIENCE OF S139 RICHARD FEYNMAN: S145 THE IMPORTANCE OF THE INTERNET NO ORDINARY GENIUS BEING INTERESTED S136 HOW WAS IT FOR YOU?

S142 ETHICS AT THE CUTTING EDGE 4pm 5pm 6pm 7pm 8pm 9pm 10pm

E SEC = SANDFORD EDUCATION CENTRE CLC = CHELTENHAM LADIES’ COLLEGE SA = ST ANDREW’S CHURCH QUEEN’S = THE QUEEN’S HOTEL HELIX = MRC HELIX THEATRE QFAMILY EVENT 29 LABORATORY: BIOMEDICAL HUB

A WORLD OF SURGERY WITH ROGER KNEEBONE

We’re committed to giving our audiences the opportunity to meet some of the best biomedical scientists and to hear about EVENTS AT THE SCIENCE FESTIVAL their latest research, so we’re thrilled Who Holds the Scalpel? p.25 that our four Festivals have become a Ethics at the Cutting-edge p.40 biomedical hub for events like these. We Free sessions on cutting-edge surgical technology want to take this further, developing this on Sat 8 June and Sun 9 June, 10am - 4pm in the ExperiTent programme into a national showcase for biomedical research. Don’t miss our other biomedical events, including: LabOratory lets us put biomedical Maurice Saatchi’s Medical Innovation Bill p.13 science in the spotlight in a series Stroke p.15 of events across all four Festivals. The Science and Art of Patient Care p.20 So if you enjoy what you hear at the Intensive Care with Kevin Fong p.24 Science Festival, you can now join in the Intricate Operations, No More Scalpels? discussion all year round. and Emergency Trauma medical workshops at Visit cheltenhamfestivals.com/ Sandford Education Centre (p.31 and p.37) laboratory for more information.

HOW DO THE FESTIVALS MAKE YOU FEEL? HAPPY EXCITED INTRIGUED INSPIRED SURPRISED AMUSED FASCINATED AMAZED For the first time ever, this year we will be conducting a unique experiment to find out how the four Cheltenham Festivals make people feel. The Jazz, Science, Music and Literature Festivals obviously have an impact on Cheltenham from a cultural and economic perspective, but this is the first time that we have ever investigated the emotional impact of the Festivals on audiences and Festival-goers. With the help of our partners, Plymouth University (i-DAT) and Warwick University, we’ll be starting the research very soon and you will be able to see real time results online later in the year. Sign up for Festival alerts at cheltenhamfestivals.com/subscribe to get the latest news.

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30 Box Office: 0844 880 8094 SATURDAY8JUNE cheltenhamfestivals.com/science

EXTRAORDINARY EVERYDAY IN ASSOCIATION WITH GLOUCESTERSHIRE HOSPITALS Go behind-the-scenes of the NHS with our selection of hands-on workshops at Sandford Education Centre in Cheltenham. Plus, explore the FREE Have-A-Go Healthcare Science Zone. Visit cheltenhamfestivals.com/extraordinary-everyday for more information. INTRICATE OPERATIONS NO MORE SCALPELS? EMERGENCY TRAUMA Sandford Education Centre Sandford Education Centre Sandford Education Centre S086 10am – 12pm S090 10.30am – 12.30pm S095 11am – 1pm S087 1 – 3pm S091 1.30 – 3.30pm S096 2 – 4pm £10 (£8) Members 10% off £10 (£8) Members 10% off £10 (£8) Members 10% off Over 12s only Over 12s only Over 12s only Please arrive 20 minutes before your Please arrive 20 minutes before your Please arrive 20 minutes before your allocated time. allocated time. allocated time. How does a surgeon operate on the In this fascinating series of workshops Did you know Cheltenham General is tiniest part of an eye? What does a find out about the technology and one of the only hospitals in the world broken voice look like? And how do human skill that enables surgeons to offering keyhole aneurysm repair? doctors and nurses care for new- perform intricate operations without This is a chance to meet this ground- born babies in intensive care? In this scalpels. Try your hand at rebuilding a breaking team and try their high-tech selection of workshops, explore the sportsman’s knee, snake through the training equipment, find out what world of micro-surgery and get hands- colon with a mini camera and get behind emergencies are really like with Simon on with realistic operation simulations the scenes with the NHS specialists who the Patient Simulator and have a go at used by real surgeons in training. keep hearts pumping. rebuilding a jaw, eye socket or nose.

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CLIMATE: A VERY FLEXIBLE SHORT INTRODUCTION INHERITANCE: EPIGENETIC-EFFECTS S088 Parabola Arts Centre 10 – 11am ON HEALTH £8 (£7) Res Members 10% off S089 MRC Helix Theatre What is the difference between the 10.15 – 11.15am climate and the weather? How do the £8 (£7) Members 10% off oceans and the atmosphere distribute DNA contains all the instructions that the Sun’s energy around the planet? make you who you are. But there is What is El Niño? What are the real threats another set of rules which scientists of climate change? Geographer Mark are coming to realise may alter how we Maslin sheds light on the many factors think about inheritance. These hidden CONTROLLING THE that control our climate and how it influences, called the epigenome, mean MIND AND SLICING affects life on Earth. that events like childhood trauma and THE BODY WITH LIGHT famine – in your grandparents’ lives – can be passed down generations to S092 Pillar Room impact your and your children’s health. 10.30 – 11.30am Join Nessa Carey, Anne Ferguson- £8 (£7) Members 10% off Smith and Wolf Reik as they discuss It may seem impossible, but we are now epigenetics and what it may mean for able to control the brain by flashing a our daily lives. light on it – this is optogenetics. Watch

as Mark Lythgoe, Amit Jathoul and Clare Elwell reveal cancer cells that glow, use light to detect early signs of autism and shed light on the brain before your very eyes in a new revolution of optical imaging and control of the body! With a live link to the CABI imaging labs at UCL.

Search for an event using the QUICKFIND CODE at cheltenhamfestivals.com to go straight to the right page 31 Box Office: 0844 880 8094 SATURDAY8JUNE cheltenhamfestivals.com/science

IS MY IMMUNE SYSTEM NORMAL? S098 MRC Helix Theatre 12.15 – 1.15pm £8 (£7) Members 10% off Over the winter, every other advert tells us we need to boost our immune systems: they imply that if we get one cold, it’s proof that our immune system BANG GOES THE must be failing; two and we’re not FIREWORK normal. But how do you know what’s normal? Join immunologists Joanna S100 EDF Energy Arena Sheldon, Arne Akbar and Rick Maizels 2 – 3pm RASPBERRY Pi as they discuss what effect factors £9 (£8) Res Members 10% off WORKSHOP like age, stress, exposure to microbes and your genes have on your immune What makes a firework whistle, crackle or St Andrew’s Church system while Vivienne Parry does her bang? How are the different colours made? Using spectacular demos, Ron Lancaster S093 11am – 1pm best to find out what’s normal. explores the explosive chemistry behind S094 2 – 4pm fireworks and pyrotechnics. Includes £12 (£10) Members 10% off flashes and loud noises! Ever wanted to try computer A member of the Society of Biology programming? A Raspberry Pi is a computer the size of a credit-card but it can do everything your desktop PC can, and has vast potential. From writing your own games, building robots, taking time-lapse photos to controlling a coffee machine: you will be amazed at what it can do. Explore the fascinating and fun world of computer science with Raspberry Pi engineer and evangelist Rob Bishop and have a go at programming your very own Pi. No previous experience necessary!

THE WEB AND US HAPPY BIRTHDAY MRC: CELEBRATING HOW HORIZON S099 Pillar Room A CENTURY OF REPORTED THE WORLD 12.45 – 1.45pm CHANGING LIVES AND CHANGED IT £8 (£7) Members 10% off It’s not a coincidence that patterns of S101 MRC Helix Theatre S097 EDF Energy Arena connectivity in our brains are similar to 2.15 – 3.15pm 12 – 1pm the patterns of connectivity on the Web. £8 (£7) Members 10% off £8 (£7) Res Members 10% off The Web is not trying to replicate human You are invited to the 100th birthday The last fifty years have seen remarkable intelligence, but it might be getting close because of the way that we, as humans, party of the Medical Research Council, advances in science. But at its heart the hosted by presenter Vivienne Parry, same eternal questions remain – What use it. How will it continue to evolve? Guest Director Wendy Hall leads this with eminent scientists and prominent is out there? Where did we come from? public figures. Celebrate the best What is life? For almost half a century discussion about how society is shaping the Web as the Web is shaping society, advances in medical research of the the BBC’s flagship Horizon series has past century, as voted for by you; see documented the stories of the scientists with neuroscientist Uta Frith, social scientist Aleks Krotoski and Artificial if discoveries such as insulin, DNA, who have wrestled with these questions. vaccines, MRI or stem cells have taken Current Editor Aidan Laverty and Intelligence engineer Nigel Shadbolt. Joined on stage by Twitter chair Bill the top spot in the hearts and minds of contributors past and present look at the the British people. science through the lens of the day. Thompson.

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THE HAZARDS OF LIFE AGEING FAST AND SLOW DRAW YOUR ALLERGY S102 Winton Crucible S104 Pillar Room S106 Eureka Tent 2.30 – 3.30pm 3 – 4pm 4.30 – 6pm £8 (£7) Res Members 10% off £9 (£8) Members 10% off £10 (£8) Members 10% off There is risk in everything we do, but Heart attacks and stroke are responsible Why do so many of us get allergies? what should we actually be worried for one UK death every six minutes. As What’s happening inside your body and about? What is the chance of being we age, our risk of developing these could this inspire a work of art? Using harmed by breast screening, a value- diseases increases as part of the normal clues found in images from science burger shortening your life or being hit ageing process. However, children with and art, immunologist Donald Palmer by a meteorite? The upside of chance a rare genetic disease called Progeria and artist Lizzie Burns give a quirky could mean you win the lottery, but age prematurely and often die of heart introduction to allergies. Join them in is the risk of driving to buy the ticket disease as if they were elderly. Researchers a workshop and get creative to make worth it? David Spiegelhalter explores Joanna Bridger and Ian Kill are looking something unique to take home! how we play the odds every day, how for a treatment to help these children, we feel about the threats we face and but a treatment may also give Cathy how statistics can help with life’s endless Shanahan a way to tackle ageing itself. series of choices. A member of the Society of Biology

WENDY HALL

IS THE WEB CHANGING SOCIETY? ALBERT EINSTEIN: S107 Parabola Arts Centre RELATIVITIVELY 4.30 – 5.30pm SPEAKING £8 (£7) Res Members 10% off Only 20 years old, yet the World Wide S103 Parabola Arts Centre Web has changed our lives already. 2.30 – 3.30pm ANATOMY SCAN: LIVE But what is its impact on society? Is £10 (£8) Res Members 10% off it shaping how we think? How we S105 By Tangram Theatre Company EDF Energy Arena interact with one another? How we 4.15 – 5.45pm Einstein possessed one of the conduct our lives on- and offline? £10 (£8) Res Members 10% off greatest minds and the über coolest And how might it shape us in the moustaches of the twentieth century. In an anatomy lesson with a big future? Guest Director Dame Wendy Combining comedy songs, clowning difference, BBC presenterMichael Mosley Hall shares her thoughts on what the and gloriously bad puns alongside and consultant radiologist Iain Lyburn Web means for society and for us as proper explanations of the science send a volunteer off for a full-body MRI individuals. behind his landmark theories, this scan courtesy of Cobalt Imaging Centre, show is a hilarious and thought- Cheltenham. With a live feed from the provoking answer to everything you scanner, explore what your insides look ever wanted to know about Einstein like, why things are where they are and but were too afraid to ask. how everything is joined together. A PAC and Cheltenham Science Festival In association with Cobalt co-promotion.

Book ahead with Cheltenham Festivals Membership 33 Box Office: 0844 880 8094 SATURDAY8JUNE cheltenhamfestivals.com/science

BIRDWATCHING S112 EDF Energy Arena 6.45 – 7.45pm £10 (£8) Res Members 10% off There are around 10,000 species of bird in the world and ornithologist Tim Birkhead has spent his life studying quite a number of them. He shares his THINKING WITHOUT THE LIFE OF BRAIN knowledge of bird brains and behaviour WORDS with James Watson, who brings tales of S110 Parabola Arts Centre time spent indulging his passion for bird- S108 Winton Crucible 6.30 – 7.30pm watching – the pastime that originally 4.45 – 5.45pm £9 (£8) Res Members 10% off took him into zoology and matured into a serious interest in genetics. £8 (£7) Res Members 10% off The most complex system in the Words are not the only ways in which Universe, 1.4kg of a jelly-like substance we communicate. This is no more with one hundred billion cells: your evident than in a dance partnership, brain. Yet how does it work? How does where two people need to understand it control your movements, store your each other without uttering a single memories or allow you to see? How word; their bodies say it all. Argentine does it make you who you are? Join Jack Tango partners, neuroscientist Nicky Lewis for an introduction to your most Clayton and artist Clive Wilkins, precious organ. explore the notion of thinking and acting without words and encourage us to use our imaginative powers to think outside the box of traditional RASPBERRY Pi: communication. IMAGINARIUM S111 MRC Helix Theatre THINKING WITHOUT 6.30 – 7.30pm MICHAEL MOSLEY WORDS & TANGO £8 (£7) Members 10% off DANCE CLASS At less than £30, the Raspberry Pi is a cheap, credit-card-sized computer. S109 Winton Crucible It’s easily programmed at home and MICHAEL MOSLEY: & Pillar Room readily connected to different bits THE FAST DIET 4.45 – 7pm of kit through its ‘PiFace’. With it, you £16 (£14) Res Members 10% off can create programming solutions to S113 Winton Crucible Ticket includes Talk (S108) real-world problems: a cupboard that 7 – 8pm and Dance Class (S109) tweets when you snack late at night, £10 (£8) Res Members 10% off a bird box that snaps photos of your You have heard the theory, now get elusive feathered friends and so much BBC presenter Michael Mosley has a the chance to put it into practice as more. Join Raspberry Pi Evangelist Rob radical new approach to weight loss. Nicky and Clive lead you through a Bishop, computer scientist Andrew Scientific trials of Intermittent Fasting tantalising Argentine Tango taster Robinson and colleagues to explore and have shown that it will not only help session exploring an alternative way be inspired by the great things you can the pounds fly off, but also lower your to capture thoughts – a new way of do with a Raspberry Pi. risk of a range of diseases, including thinking. diabetes, heart disease and cancer. No need to bring a partner. He talks about his latest book, dieting phenomena and the science behind it all.

34 Search for an event using the QUICKFIND CODE at cheltenhamfestivals.com to go straight to the right page Box Office: 0844 880 8094 SATURDAY8JUNE cheltenhamfestivals.com/science

EXTREMES: LIFE, DEATH AND THE LIMITS OF THE HUMAN DIRECTOR’S BODY PICK S114 MRC Helix Theatre 8.30 – 9.30pm £9 (£8) Members 10% off How do our bodies respond to extremes of heat, cold, vacuum, altitude, age or disease? With gripping accounts of extraordinary events, Kevin Fong reveals how science, technology and medicine have made what was once lethal survivable. He takes us to the limits where life is balanced on a knife edge to explore how our bodies work, what life is, and what it means to be human. SHAKESPEARE’S MEDICINE CABINET S116 Parabola Arts Centre 8.45 – 10.45pm £15 (£13) Res Members 10% off Shakespeare often refers to drugs, poisons and medicines in his plays, with some of his plots – Romeo and Juliet and Hamlet, for example – depending absolutely upon their use. But were these references merely dramatic license or was there real science behind them? Find out with pharmacologist Rod Flower and Shakespearean scenes from a troupe of actors.

WHAT MAKES INSECTS TICK? HOW A member of the Society of Biology DO YOU SMELL TO A MOSQUITO? S118 Winton Crucible SCIENCE BURLESQUE: 13 9 – 10pm The Innocent Joy of Discovery £9 (£8) Res Members 10% off at the Heart of Science, Plied Complimentary refreshments will be Insects couldn’t be more different from with Absinthe Till it Wakes in a provided during the short interval. humans; they wear their skeletons on Stranger’s Bed the outside, breathe through the sides of their bodies and have some parts S115 Pillar Room STAND-UP MATHS 2013 that look almost alien. Join James 8.45pm – Late Logan from the London School of £15 (£13) Members 10% off S117 EDF Energy Arena Hygiene & Tropical Medicine and BBC You’d be surprised how many scientists 8.45 – 9.45pm Four’s Insect Dissection to look inside secretly want to dress up in a corset £15 (£13) Res Members 10% off the bodies of some well-known six- and swap the bright, shiny lab for the legged pests and discover their special The UK’s foremost and only Stand-up features, such as a mosquito’s amazing dark, seedy cabaret. Tonight, some of Mathematician is back in Cheltenham for them will get the chance. You may be sense of smell. what is statistically likely to be another entertained, thrilled, amused, excited and sell-out show. From Rubik’s Cubes to disturbed, but you won’t be educated... binary numbers, Matt Parker covers not about science anyway. Chemistry his current favourite bits of maths in a and conjuring, mathematics and music comedy show accessible to everyone. and, of course, biology and burlesque. Featuring all-new material, come and Definitely NOT for children. watch him not divide by zero, live on The bar will be open during this event stage! “Capable of generating big laughs using the deceptively simple power of numbers” (Guardian)

Enjoy discounts and special offers all year round with Cheltenham Festivals Membership 35 EPSRC Supporting the Cheltenham Science Festival

Visit our Advanced Materials interactive exhibit in the Discover Zone to learn more about graphene, LEDs and metamaterials.

GRAPHENE LEDs METAMATERIALS

EPSRC is the main UK government agency for funding research and training in engineering and physical sciences, investing around £800 million a year in research to help the nation handle the next generation of technological change. Visit our web site at www.epsrc.ac.uk to find out more about us.

Join us The secretsSecrets ofof creativeCreative people People 4 June 6pm- 6:00 - 7:00 pm at events Is the SiliconAge of SiliconAge Over? Over? throughout 7 June 12.15pm- 12:15 - 1:15 pm the Festival Autonomous forRobots the people including: 7 June 6.30pm- 6:30 - 7:30 pm

Energy harvestingHarvesting 7 June 8.30pm- 8:15 - 9:15 pm Box Office: 0844 880 8094 SUNDAY9JUNE cheltenhamfestivals.com/science

EXTRAORDINARY EVERYDAY IN ASSOCIATION WITH GLOUCESTERSHIRE HOSPITALS Go behind-the-scenes of the NHS with our selection of hands-on workshops at Sandford Education Centre in Cheltenham. Plus, explore the FREE Have-A-Go Healthcare Science Zone. Visit cheltenhamfestivals.com/extraordinary-everyday for more information. INTRICATE OPERATIONS NO MORE SCALPELS? EMERGENCY TRAUMA Sandford Education Centre Sandford Education Centre Sandford Education Centre S119 10am – 12pm S124 10.30am – 12.30pm S127 11am – 1pm S120 1 – 3pm S125 1.30 – 3.30pm S128 2 – 4pm £10 (£8) Members 10% off £10 (£8) Members 10% off £10 (£8) Members 10% off Over 12s only Over 12s only Over 12s only Please arrive 20 minutes before your Please arrive 20 minutes before your Please arrive 20 minutes before your allocated time. allocated time. allocated time. How does a surgeon operate on the In this fascinating series of workshops Did you know Cheltenham General is tiniest part of an eye? What does a find out about the technology and one of the only hospitals in the world broken voice look like? And how do human skill that enables surgeons to offering keyhole aneurysm repair? doctors and nurses care for new- perform intricate operations without This is a chance to meet this ground- born babies in intensive care? In this scalpels. Try your hand at rebuilding a breaking team and try their high-tech selection of workshops, explore the sportsman’s knee, snake through the training equipment, find out what world of micro-surgery and get hands- colon with a mini camera and get behind emergencies are really like with Simon on with realistic operation simulations the scenes with the NHS specialists who the Patient Simulator and have a go at used by real surgeons in training. keep hearts pumping. rebuilding a jaw, eye socket or nose.

A map will be sent with your tickets

RORY WILSON

MIND CONTROLLING ANIMAL DIARIES PAIN: WHY DOES IT MICROBES HURT SO MUCH? S121 Winton Crucible S123 MRC Helix Theatre 10 – 11am S126 Pillar Room 10.15 – 11.15am £8 (£7) Res Members 10% off 10.45 – 11.45am £8 (£7) Members 10% off For more than 30 years Rory Wilson £8 (£7) Members 10% off Think your decisions are your own? has been inventing special high-tech Pain is an important warning signal that They may not be if you are suffering tags and attaching them to wild can help us to avoid harm, but for people from microbial mind control! Microbes animals in an attempt to understand living with prolonged, chronic pain it can persuade crickets to take a suicidal more about them. Starting with can have devastating consequences. leap and turn ants into infectious time penguins and moving to armadillos, Neuroscientist Stephen McMahon bombs. They can even make humans sloths and even sharks, his work has researches the causes of chronic pain more likely to crash cars and could be given him access to their daily lives. He and new ways to treat it. He is joined by a factor in schizophrenia. Join Joanne joins us with some incredible footage researcher and consultant neurologist Webster, Ben Bleasdale, Charlotte and reveals some of the animal secrets David Bennett who works with patients Sayers and FameLabber Lucy he has uncovered. suffering from nerve damage. Thorne to find out who’s making your decisions.

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THE AGEING IMMUNE CALL MY GENETICALLY SYSTEM ENGINEERED BLUFF S131 Pillar Room S133 Pillar Room 12.45 – 1.45pm 3 – 4pm £9 (£8) Members 10% off £9 (£8) Members 10% off As we get older we become more A complex algorithm of an event, during susceptible to sickness, cancer, which some eminent machines probe, pneumonia and other illnesses. Right? modify, and tell outrageous porkies Not necessarily. Specialists Donald about the nuts and bolts of obscure Palmer, Arne Akbar and Thomas von technological words and phrases. Base Zglinicki explore how age effects your pair Kathy Sykes and Mark Lythgoe, immune system and how, in your youth, lead the research, assisted by Timandra you can prepare it for the challenges Harkness, Helen Arney, Frank Burnet ahead. and Matt Parker. Uncivil engineer Marcus Moore draws doodles of their findings on the back of an envelope.

A DOG NOSE BEST S129 EDF Energy Arena 12 – 1pm £9 (£8) Res Members 10% off Dogs: they’ve been man’s best friend for thousands of years and in that time we have learned to rely on their enhanced sense of smell to do a variety of jobs. Hear how Gloucestershire Police use dogs to sniff out drugs, cash and arms, how Alex Butler trains dogs to find missing people and how Claire Guest is learning from dogs how to detect bladder cancer. Each brings their canine companion to the stage. Be prepared for our police dog to search the audience in a demonstration!

JAMES GLEICK: THE MARS CURIOSITY: INFORMATION THE NASA ROVER BRAIN ENHANCING S132 EDF Energy Arena S134 EDF Energy Arena DRUGS: WOULD YOU? 2 – 3pm 4 – 5pm £9 (£8) Res Members 10% off £9 (£8) Res Members 10% off S130 MRC Helix Theatre 12.15 – 1.15pm Our world relies on information, from Since its dramatic landing on the red £8 (£7) Members 10% off African talking drums to letters to planet back in 2012, NASA’s Mars texting. The mode might have changed, Curiosity Rover has identified a dry If you could take a drug to boost but the underlying principle remains: we riverbed, drilled samples of rock, sent your brain power, would you? Should are sending, storing and communicating back thousands of photos and even everyone? But what if it only works for a knowledge. James Gleick, author of The posed for a self-portrait. Join Curiosity small number of people; is it fair for only Information and winner of 2012’s Royal science team member and geologist a few to benefit? NeuroscientistsBarbara Society Winton Prize for Science Books, Sanjeev Gupta and astrobiologist Sahakian and Elizabeth Tunbridge joins us to talk about information – how and FameLabber Lewis Dartnell for and ethicist Julian Savulescu explore we use it and why. an update – hot off the NASA presses cognitive enhancers, how they work, who – on what Curiosity is up to, what our they work for and the ethics of taking discoveries tell us about life on Mars these drugs. and whether there is still hope for life

on other planets. In association with NASA

A member of the Society of Biology

38 Book ahead with Cheltenham Festivals Membership Box Office: 0844 880 8094 SUNDAY9JUNE cheltenhamfestivals.com/science

ARE YOUR MAGISTERIA OVERLAPPING? S135 Winton Crucible 4.15 – 5.15pm £10 (£8) Res Members 10% off Science. Religion. Religion. Science. Always having a pop at each other, demanding we take sides. But maybe our magisteria don’t need to overlap. Maybe we just need to accept that science and religion, as Stephen Jay Gould put it, each have a ‘legitimate magisterium or domain of teaching authority’. Welcome to NOMA. (That’s Non-Overlapping Magisteria.) Still with us? Robin Ince is, and so is Reverend Richard Coles. They are joined by Bishop of Swindon Lee Rayfield and a scientist to tread gracefully along the borders of our equally enchanting magisteria. In association with Greenbelt Festival and

IAIN STEWART

RICHARD FEYNMAN: NO ORDINARY GENIUS RISE OF THE S139 KATHY SYKES & MARK LYTHGOE CONTINENTS MRC Helix Theatre 6.15 – 7.15pm S138 EDF Energy Arena £10 (£8) Members 10% off 6 – 7pm Richard Feynman was perhaps the most HOW WAS IT FOR YOU? £10 (£8) Res Members 10% off brilliant and influential of physicists – S136 Eureka Tent The Earth’s continents are the architect of quantum theories, enfant 5 – 6pm FREE wreckage of a much larger long-lost terrible of the atomic bomb project, supercontinent – Pangaea. Geologist ebullient bongo-player and storyteller, An opportunity to give Festival Directors Iain Stewart reveals the clues to and an inspiration to thousands. His Kathy Sykes and Mark Lythgoe your this ancient past that lie in our rocks, colourful life and clever mind have been views on this year’s Cheltenham Science landscapes and even in animals. With documented by biographer James Festival and to contribute ideas for the clips from the series, he shows how Gleick and film-maker Christopher future. defining moments have fundamentally Sykes. They join comedian Robin Ince changed our continents’ characters – who wished he had become a scientist LANDGRABBERS – transforming evolution, forging after encountering Feynman’s work – to incredible economic riches and share their stories of a genius. S137 Pillar Room changing the course of human history. 5.30 – 6.30pm £9 (£8) Members 10% off Across the world, parcels of land the size of Wales – used by subsistence farmers, cattle herders and forest tribes – are being bought by City speculators, Gulf oil sheikhs, Chinese entrepreneurs and industry titans like Richard Branson. It’s RICHARD FEYNMAN all in the name of feeding the world, but will it? Fred Pearce lifts the lid on a practise that will have profound implications for global conservation and food availability.

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THE OVER-AMBITIOUS DEMO CHALLENGE 2013 S140 Winton Crucible 7 – 8.15pm £10 (£8) Res Members 10% off Expect madness and mayhem as Steve Mould and Andrea Sella once again host the infamous Science Festival Demo Challenge. This year’s contestants Zoe Laughlin, Stefan Gates and defending champion Ian Simmons take to the lab bench as they try to out-do each other ROBIN INCE with even more spectacular, impressive and show-stopping science demos. Who gets your vote?

Messier-Bugatti-Dowty

HELEN ARNEY ETHICS AT THE CUTTING EDGE S142 ExperiTent 7.30 – 8.30pm LAB NOTES: SONGS THE IMPORTANCE OF £9 (£8) Members 10% off FROM SCIENCE BEING INTERESTED When removing a tumour, it’s not always S144 Pillar Room S145 MRC Helix Theatre easy to distinguish between cancer and 8 – 9pm 8.15 – 9.15pm healthy tissue, and sometimes too much £10 (£8) Members 10% off £10 (£8) Members 10% off tissue is removed or the cancer is left behind. The Intelligent Knife is a new tool Singer-songwriter from Radio 4’s The Comedian Robin Ince explains the joy that gives instant feedback to surgeons – Infinite Monkey Cage Helen Arney of realising that being self-conscious while they cut – transforming operating delights in writing the world’s most in a big universe is a darn good thing. decisions. Breakthroughs like this can scientifically accurate songs. Jonny Find out why we have eyebrows, why revolutionise surgery, but when should Berliner, Andrew Pontzen and guests bald dogs have bad teeth and how new technology become everyday join her to perform a natural selection heavy metal music makes pigs deaf. practice? Who makes these decisions? of their statistically significant songs This is a loving look into the minds of How much say should we have? Join using precise scales and finely-tuned two giants of human imagination – Professor of Surgical Education Roger instruments. These songs are outliers Charles Darwin and Richard Feynman Kneebone and a team of surgeons for you don’t want to dismiss. – stopping off on the way to look at the discussion. some of the more bizarre views of early science. Messier-Bugatti-Dowty The bar will be open during this event Messier-Bugatti-Dowty

40 Enjoy discounts and special offers all year round with Cheltenham Festivals Membership We are pleased to support the Cheltenham Science Festival 12th-18th October

Biology Week is a celebration of all aspects of the biosciences.

For more information, including ways that you can get involved, visit www.societyofbiology.org/biologyweek Box Office: 0844 880 8094 FAMILY cheltenhamfestivals.com/science

WEDNESDAY 5TH JUNE SATURDAY 8TH JUNE

AS IF BY MAGIC SF01 Winton Crucible 6.30 – 7.30pm £6 Res Members 10% off Age 10 upwards Boiling liquids that are too cold to touch? Objects that disappear in a flash of light? Invisible fire extinguishers? It may seem like magic, but it’s really chemistry! Meet magical molecules and enchanting elements with Andrew Szydlo. Experience explosions, flashes and whizzes using liquid nitrogen, carbon STEFAN GATES & ANDREA SELLA dioxide gas and hydrogen. It’s the magic of chemistry!

CRIME SCENE STEFAN GATES AND INVESTIGATION ANDREA SELLA: ALL STEAMED UP Eureka Tent SF03 9.45 – 10.45am SF08 Winton Crucible SF04 11.15am – 12.15pm 10 - 11am SF05 12.45 – 1.45pm £6 Res Members 10% off SF06 2.15 – 3.15pm Age 6 upwards £8 Members 10% off Gastronaut Stefan Gates and chemist Age 11 upwards Andrea Sella attempt to create a meal A leading researcher has developed an using only the power of steam! With the amazing new material with incredible help of a vegetable oil powered steam tractor and the laws of thermodynamics, ANDREW SZYDLO properties under extreme conditions – attracting much attention – but he has they set food alight, use fire extinguishers been found murdered and all the data in unusual ways and make microwave- and specimens stolen… whodunit? meringue. Will they succeed and will a The investigation team has recovered meal appear before your eyes? key pieces of evidence from the scene and they need your help to identify the FRIDAY 7TH JUNE culprit. Using microscopy, spectroscopy, finger print analysis and 3D-printing, can you solve the crime? WORLD OF SURGERY SF02 ExperiTent 4.30 – 5.30pm £7 Members 10% off Age 14 upwards Emergency! An interactive session which brings the world of surgery to TALON-SPOTTING life. Come and meet the ambulance SF07 EDF Energy Arena crew and operating team who put you 10 – 11am back together after an emergency. £6 Res Members 10% off Find out what you could do to help in Age 10 upwards such an emergency and what happens to patients as they are loaded into an Come face-to-face with some of nature’s ambulance and taken to hospital. These most impressive winged predators – simulations are similar to those being eagles, hawks and owls – and feel the used for training medical staff and give draught of their wings as they pass over an excellent insight into the world of your head. Join Jemima Parry-Jones medicine and the careers of those who from the International Centre for Birds of work within it. Prey and her feathered friends to discover how birds of prey hunt, mate and survive. Just make sure you duck… In Association with the International Centre for Birds of Prey

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DAREDEVIL LABS: EVEREST SF09 Parabola Arts Centre 12 – 1pm £6 Res Members 10% off Age 12 upwards Fresh from the highest lab in the world, BBC presenter Greg Foot and mountaineer Nick Insley join us to talk about their recent scientific adventure to Mount Everest. There, they and their bodies to the limits to uncover cutting-edge medical treatments to save lives back home. With a host of demos including an explosive display of why you need oxygen, a live look at red blood cells and a brilliant full-audience experiment to uncover your hidden genetics, this is a show you don’t want to miss. FIRE: FRIEND OR FOE? SUNDAY 9TH JUNE SF11 The Cheltenham Ladies’ College, Princess Hall DINOSAUR DIG 3 – 4pm Eureka Tent £6 Members 10% off SF13 10 – 11am Age 6 upwards SF14 11.30am – 12.30pm Cooking fires, campfires, fireworks – we SF15 1 – 2pm use fire for all sorts of things. It heats our SF16 2.30 – 3.30pm food, lights our way and keeps us warm, £7 Members 10% off but it can also be dangerous. See the Age 4 upwards spectacular chemistry behind burning, flames and the fire triangle with lots of Search for dinosaur bones in our dig pit exciting and flashy demonstrations. Join with fossil hunter Ed Drewitt and his Matt Chalmers from The Cheltenham team. Do the bones belong to a meat Ladies’ College for some fuel-injected fun or plant eater? Can you piece together and see the explosive results! Is fire your the South West’s very own dinosaur, the friend or your foe? Thecodontosaurus? Get your hands on some real prehistoric fossils and make your own bones to take home. In association with the University of Bristol PERIODIC SUCCESS SF10 Winton Crucible 12.15 – 1.15pm £6 Res Members 10% off EXTREME SPORTS IN Age 11 upwards SPACE Which element makes you reek of garlic? Why do we love gold? What SF12 MRC Helix Theatre is the disgusting secret of antimony? 4.30 – 5.30pm The periodic table is the playground £6 Members 10% off of chemists and with their touch it can Age 11 upwards produce explosions, poisonings and awesome coloured flames. Join chemical Earth-bound thrill seekers climb the physicist and FameLabber Jamie biggest rocks and surf the best waves Gallagher as he puts elements through to get an adrenaline fix. But what if their paces and tests them to destruction. we could go anywhere in the Solar Guiding you through the periodic System? Would wakeboarding on the table, he brings elements to life with methane seas of Titan satisfy our needs? enthusiasm and demonstrations. Or would jumping a 7 km Mars canyon be the ultimate thrill? Astronomer and adventurer Huw James takes you on a space voyage to seek out the best spots for extreme sports in our Solar System.

44 Search for an event using the QUICKFIND CODE at cheltenhamfestivals.com to go straight to the right page Box Office: 0844 880 8094 FAMILY cheltenhamfestivals.com/science

THE BIG BOOK OF THE SCIENCE OF THE NATURAL HISTORY INTERNET SF19 MRC Helix Theatre SF21 MRC Helix Theatre 2.15 – 3.15pm 4.15 – 5.15pm £6 Members 10% off £6 Members 10% off Age 6 upwards Age 7 upwards Experience a 4 billion year story in sixty What is the internet and how does it minutes with the help of Chris Lloyd work? How does information fly round and the biggest book you have ever the world in the blink of an eye? 40 seen! Choose objects from the pockets years after Britain’s first connection to of his multi-coloured coat to help build the internet, our resident boffins, the a huge tapestry that tells the entire story 2007 FameLab finalists, take you on a of life and evolution on our planet, from scientific journey of cryptography, lasers astrophysics to zoology. and deep sea plumbing. Find out what really goes on when we browse the Web, email and send a tweet in a show packed with live demos.

TSUNAMI SURVIVAL SF17 EDF Energy Arena 10 – 11am £6 Res Members 10% off Age 10 upwards More powerful than a runaway train with waves as high as 70 feet tall, tsunamis are one of the most awesome forces on the planet, causing serious destruction each year. But how do scientists study these devastating waves? Would you know what to do if you were face to face with a giant wall of water? Join BBC presenter Iain Stewart and British Geological Survey scientists Dave Tappin and Suzanne Sargeant to see what happens when a defenceless LEGO town meets a killer wave.

FRAN SCOTT DR YAN

DO YOU SEE WHAT I SEE? SF20 Winton Crucible 2.15 – 3.15pm SCIENCE £6 Res Members 10% off MISADVENTURES Age 11 upwards Do you see what I see? If you are a mantis SF18 Winton Crucible shrimp you won’t! Compared to them, MORE FAMILY 12 – 1pm our eyes have evolved to see only a tiny £6 Res Members 10% off fraction of the multi-coloured world FRIENDLY EVENTS Age 5 upwards around us. Bang Goes the Theory’s Dr Yan Bang Goes the Firework p.32 Are you stronger than friction? Is shows how we can harness the secret Albert Einstein: hydrogen really that explosive? Find out world of light to do amazing things. Find Relativitively Speaking p.33 as you enter the crazy world of BBC’s out how to use a TV remote like a torch, burn things at a distance using invisible The Over-Ambitious Demo Demo Diva Fran Scott as she provides Challenge 2013 p.40 a high octane, fast-paced hour of light, and what you look like through the interactive fun! Daring and downright eyes of a butterfly. A Dog Nose Best p.38 nutty demonstrations await: witness Animal Diaries p.37 bangs and surprises with a flair that only FameLab International Final p.25 science can deliver.

Enjoy discounts and special offers all year round with Cheltenham Festivals Membership 45 EDUCATION

TELL ME ALL ABOUT IT Choose from a wide range of workshops and events for Key Stages 1-4 to create your perfect day out. Complement your visit with a free session in the Discover Zone or the ExperiTent. If you have breaks in your itinerary, have a go at the Discovery Trail in Imperial Gardens. Alternatively, let SCIENCE us organise your day for you – book a Day FOR SCHOOLS 2013 Package for KS3 or a Mini Package for KS1. WORKSHOPS AND EVENTS Welcome to Science for Schools 2013. The Education Our exciting hands-on workshops are programme brings energy to the Festival weekdays, designed for class-sized groups and last with hundreds of pupils buzzing around the site for one hour. Events are hour-long science getting stuck into science, interacting with scientists, shows for large audiences presented by and honing their curiosity. So we are delighted to top-notch science communicators. once again be the education and principal partner to The Times Cheltenham Science Festival. Item Price We are passionate about engaging young minds Event £5.50 p/p with science and engineering, which is why we continue to build on our rewarding partnership Workshop £6.50 p/p with the Education department at Cheltenham KS1 Mini Package £5 Festivals. Together we are embarking on an ambitious programme of STEM (Science, Technology, KS3 Day Package £14 Engineering and Maths) activities that will take place Discover Zone FREE - in conjunction all year round. The aim is to engage as many children or ExperiTent with an event/workshop and young people with STEM and the possibilities for a brilliant career in science and engineering. KS3-4 Area42 FREE - in conjunction with an event/workshop See you in June. Discovery Trail FREE Dr Andy Spurr Managing Director Raspberry Pi £10 EDF Energy Nuclear Generation workshop

The Education Team would like to thank

and all our other partners.

46 Box Office: 0844 880 8094 cheltenhamfestivals.com/science

WORKSHOPS AND EVENTS KS3 DAY PACKAGES Tuesday 4 June KS3 Day Packages are available Tuesday 4, Thursday 6 and Friday 7 June, comprising: KEY STAGE 2 • A 90 minute hands-on workshop SS02 11.30am Event: The Big Squeeze • An event SS03 10am Event: Dr Death • A guaranteed hour in the Discover Zone SS05-8 10am-2.45pm Workshop: CSI Cheltenham (times vary) The full Science for Schools 2013 KEY STAGE 3 programme, together with booking information, is available online at SS01 10am Event: The Big Squeeze cheltenhamfestivals.com/scienceforschools, SS04 12noon Event: Cracking the Code for Genetics where you can also find out about the KS2 SS09-12 10am-2.45pm Workshop: Robotics Young Scientists’ Day, KS3 Girls’ Day, and a (times vary) whole host of opportunities to engage your Wednesday 5 June pupils in science throughout the year.

KEY STAGE 1 SS51 9.30am KS1 Mini Package: Dinosaurs and Discover Zone SS52 9.30am KS1 Mini Package: Discover Zone and Dinosaurs SS15 12.15am Event: Up Up and Away

KEY STAGE 2 SS13 10am Event: Magical Maths SS14 12noon Event: Movers and Shakers SS16-20 10am-4pm Workshop: (times vary) Insides on Your Outsides

Thursday 6 June

KEY STAGE 2 SS22 12noon Event: Science- the Best Bits SS23 10.15am Event: As If By Magic SS25-28 10.30am-2.30pm Workshop: (times vary) Animals and Habitats

KEY STAGE 3 SS21 10am Event: Space and Our Place in It SS24 12noon Event: As If By Magic SS29-32 10am-2.45pm Workshop: Shocking Science (times vary)

Friday 7 June

KEY STAGE 3 SS33 10am Event: Don’t Try This At Home SS34 12noon Event: Spine Tingling Tour of the Brain SS35-38 10.15am-2.15pm Workshop: Careering Around (times vary) SS39-SS41 9.45am-5pm Workshop: Raspberry Pi (times vary)

KEY STAGE 4 SS54 11am Workshop: World of Surgery SS55 1.30pm Workshop: World of Surgery

47 DISCOVER THE OPPORTUNITIES www.glos.ac.uk/ugopen

Visit one of our open days to find out more Wednesday 5 June and Saturday 22 June PATRONS

FESTIVAL PATRON We would like to thank our Acknowledgements Kate Adie Patrons for their generous Cheltenham Festivals Board of Trustees David and Zany Anton-Smith support: Peter Bond – Chairman Mark and Maria Bentley Susan Blanchfield Alison Besterman Lewis Carnie LIFE PATRON Michael H Bond Jonathan Carr David and Jane Bruce Dominic Collier – Vice-Chairman Mark and Sue Blanchfield Jonathan and Daphne Carr Christopher Cook Peter and Anne Bond Robert Cawthorne and Catherine White Peter Elliot Dominic and Jannene Collier Andrew and Jan Clift Prof. Russell Foster Charles Fisher Simon Collings Edward Gillespie David and John Hall Mr and Mrs Andrew and Jacqueline Coyle Diane Savory Jeremy and Germaine Hitchins Lady Curtis Prof. Averil MacDonald Jonathan and Cassinha Hitchins Debra Drew and Nigel Browne Dr Gill Samuels CBE Prof. Russell Foster – Chair of Science Festival Stephen and Tania Hitchins Simon Firkins Graham and Eileen Lockwood James Fleming Chief Executive Fiona McLeod Kate Fleming Donna Renney The McWilliam family in loving memory Carol and Isabella Freeman Science Festival Advisory Group of Ruth McWilliam Clive and Stella Gardner John and Susan Singer Prof. Mark Lythgoe Prof. Russell Foster Jamila Gavin Andrew Cohen Timandra Harkness Mark and Elizabeth Philip-Sørensen Lisa Gettins Dr Roger Highfield Prof. Mark Maslin Fiona and David Symondson Jean Gouldsmith Skinner Vivienne Parry Elaine Snell Ludmila and Hodson Thornber Maurice Gran Prof. Kathy Sykes Prof. Jim Al-Khalili The Walker Family Prof. A C Grayling Quentin Cooper Mark Henderson Alex and Hattie Hambro Prof. Mark Miodownik Prof. Alice Roberts PLATINUM PATRON Dr Dawn Harper and Dr Graham Isaac Prof. Andrea Sella Dr Hannah Devlin Mike and Kerry Alcock Mike and Sally Hatcher Cross-Festival Advisory Group Jennifer Bryant-Pearson Margaret Headen Charmaine Murphy Jane Bailey Michael and Angela Cronk Mark Heywood Jane Churchill Marianne Hinton Colin Doak Marianne Hinton Dominic Collier Pamela Armstrong Lavinia Sidgwick Christine Chambers Simon and Emma Keswick Stephen Hodge Maurice Gran Dr John Bicknell Des and ChiChi Mills Anthony Hoffman and Dr Christine Facer Hoffman Tania Hitchins Anita Syvret Howard and Jay Milton Catherine Coates The Oldham Foundation Andrew and Caroline Hope Adrian and Lizzie Portlock Mrs Karen Horne With many thanks to all the staff at Dr Gill Samuels CBE Keith Jago Cheltenham Festivals, those at each venue Peter Stormonth Darling Charitable Trust Mr and Mrs JNP Kirkpatrick and the Festival volunteers, all of whom Peter and Alison Yiangou Juliet and Jamie McKelvie make the Festival happen. Mark McKergow and Jenny Clarke Contact Prof. Keith Millar and Prof. Margaret Reid GOLD PATRON If you have any specific comments about Mr and Mrs Philip Monbiot any aspect of the Festival, please email Christopher Bence Prof. Angela Newing [email protected] Jack and Dora Black Jonjo and Jacqui O’Neill Stephen and Victoria Bond Robert Padgett Registered Office Eleanor Budge Sir David and Lady Pepper 28 Imperial Square, Cheltenham, GL50 1RH Charlie Chan Leslie Perrin Reg. No. 456573 Stuart and Gillian Corbyn Hugh Poole-Warren Charity No. 251765 Vat. Reg. No. 100114013 Janet and Jean-François Cristau Jonathon Porritt Michael and Felicia Crystal Patricia Routledge CBE Photography Credits Nigel and Sally Dimmer Khal and Zoe Rudin Vittorio Luzzati Wallace and Morag Dobbin Elizabeth Saunders NASA George and Cynthia Dowty Lavinia Sidgwick Cobalt, Cheltenham Peter and Sue Elliott Phil and Jennifer Stapleton © Rolex Awards/Juergen Freund Simone Hindmarch-Bye Sharon Studer and Graham Beckett BBC BBC Radio 3 Lord and Lady Hoffmann Jonathan and Gail Taylor Tom Roberts Elizabeth Jacobs Brian Watson Charlie Chan Steven and Linda Jones Prof. Lord Winston Conor Cahill Hugh and Sue Koch Michael and Jacqueline Woof Idil Sukan Sir Peter and Lady Marychurch Fiona Yorke Raspberry Pi Sir Michael and Lady McWilliam Don Macauley Janet and Charles Middleton We would also like to thank those of CERN Keith and Verity Norton our Patrons who have chosen to remain Katie Faulks The Helena Oldacre Trust anonymous. Stephen Gunby Ian and Sarah Passmore Becky Matthews Mr & Mrs P Roberts Kalimistuk Sharon and Toby Roberts Adactio Bristol Robotics Lab Esther and Peter Smedvig For more information on becoming Jacob Forsell Andy and Ali Stalsberg a patron please contact Meredithe Stuart-Smith If you require this brochure Giles and Michelle Thorley Arlene McGlynn on 01242 537252 Michael and Rosie Warner or email arlene.mcglynn@ in large print format please Steve and Eugenia Winwood cheltenhamfestivals.com call 01242 511211.

Get closer to the Festivals with Patronage. Find out more at cheltenhamfestivals.com/patrons 49 BOOKINGINFORMATION

Book online at cheltenhamfestivals.com

Call 0844 880 8094 (5p per min at all times from landlines, mobile charges may vary)

Visit our Box Office on the 1st floor of Regent Arcade, Cheltenham KEY DATES Tues 2 April Mon 15 April Wed 17 April Mon 22 April Wed 24 April Browse programme online  Members’ booking online only  Members’ booking online, by phone & in person  Public booking online only  Public booking online, by phone & in person 

BOX OFFICE OPENING TIMES Membership discounts are for Full Members’ sole use, do not apply to Associate members or on events that include food or drink in the ticket Internet booking is available 24/7 price. Each transaction will include a £3 booking fee (£1.50 in person unless paying cash) to cover transaction costs, postage & card fees. U16s must be Before the Festival (Regent Arcade, Cheltenham) accompanied by an adult. Refunds are only available if the event is cancelled. Monday – Friday 10.30am – 4.30pm Full terms and conditions at cheltenhamfestivals.com/terms-conditions Saturday 11am – 3pm Sunday CLOSED Each transaction includes a suggested voluntary donation to Cheltenham Monday 27 May CLOSED Festivals. Find out more about donating at cheltenhamfestivals.com/support-us During the Festival (Imperial Gardens only) Please don’t forget to gift aid the donation as it increases its value to us 9.30am until the start of the last event of the day by 25% at no cost to you if you are a UK tax payer. If you wish to reduce or (phones close at 4.30pm and are not available on Sunday 9 June) remove the donation please let our team know or adjust your online basket.

Regent Arcade Shopping Centre If you have special seating needs, please call the Box Office. Cheltenham Concessionary prices are shown in brackets next to events. For more GL50 1JZ information visit cheltenhamfestivals.com/concessions

VENUES AND CAR PARKS GETTING TO THE FESTIVAL For information on public transport and car parks visit cheltenhamfestivals.com/your-visit FINDING OUR VENUES Most events are taking place in Imperial Square (GL50 1QA), and all other venues are within 3 walking distance. 4 1 Postcodes 6 5 1 Town Hall GL50 1QA 2 Sandford Education Centre GL53 7PY 3 Parabola Arts Centre GL50 3AA 4 Princess Hall, Cheltenham Ladies College 2 GL50 3EP 5 Queen’s Hotel GL50 1NN 6 St Andrew’s Church GL50 1SP

Please be considerate to local residents when parking.

50 PARTNERS

Marketing Partners Local Media Partners

Associate Partners

Event and in-kind supporters

Cheltenham Borough Council Leonora Society QAA Cheltenham College Mobenn Marquees Reading University Crown Timber Nuffield Council for Bioethics Waterstones

Cheltenham Festivals would like to thank the funders of our Digital R&D Project (Qualia) for their support.

51 4-9 JUNE 2013

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100s OF THE WORLD’S BRIGHTEST SCIENCE STARS WITH JUST 3 MINUTES TO IMPRESS… Over the last year, hundreds of scientists and engineers have surprised and impressed judges from across the world with ‘three minutes of science.’ At The Times Cheltenham Science Festival this June, finalists from 21 countries will go head-to-head in a bid to be crowned FameLab International Champion 2013.

Cheltenham Festivals created FameLab© in 2005 as a way to find and nurture scientists and engineers with the potential to be the next Brian Cox or Alice Roberts. Since then it has gone from strength OVER 5,000 to strength and developed globally, from Hong Kong to Egypt, in SCIENTISTS HAVE partnership with the British Council. In 2012 Cheltenham Festivals PARTICIPATED IN signed an agreement with NASA to run FameLab in the USA. FAMELAB SINCE IT Semi-Finals Thursday 6 June 6.45pm & 9pm p.20 STARTED IN 2005 Final Friday 7 June 6.30pm p.25

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Charity No. 251765 Cover illustration by Alex Beeching