Astl (NM 001291003) Mouse Tagged ORF Clone – MR229894

OriGene Technologies, Inc. 9620 Medical Center Drive, Ste 200 Rockville, MD 20850, US Phone: +1-888-267-4436 [email protected] EU: [email protected] CN: [email protected] Product datasheet for MR229894

Astl (NM_001291003) Mouse Tagged ORF Clone Product data:

Product Type: Expression Plasmids Product Name: Astl (NM_001291003) Mouse Tagged ORF Clone Tag: Myc-DDK Symbol: Astl Synonyms: 7420700F21; C87576; Sas1b Vector: pCMV6-Entry (PS100001) E. coli Selection: Kanamycin (25 ug/mL) Cell Selection: Neomycin ORF Nucleotide >MR229894 representing NM_001291003 Sequence: Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC

ATGGGTATCATGGGAAGCCTGTGGCCTTGGATATTAACTATGCTCTCCTTGCTAGGTTTGAGCATGGGAG CACCCTCAGCATCCAGATGTTCTGGAGTCTGCAGTACCAGTGTTCCAGAAGGCTTCACTCCTGAGGGAAG CCCGGTATTTCAGGACAAGGACATCCCCGCAATTAACCAAGGGCTCATCTCAGAGGAGACCCCAGAAAGC AGCTTCCTGGTAGAAGGGGACATTATCCGGCCAAGCCCTTTCCGATTGTTGTCAGTGACCAATAATAAAT GGCCCAAGGGCGTTGGTGGCTTTGTGGAGATCCCCTTCCTGCTTTCCAGAAAGTATGATGAACTCAGCCG CCGGGTCATTATGGATGCCTTTGCTGAGTTTGAACGTTTCACATGCATCCGGTTTGTTGCCTACCATGGT CAGAGAGACTTTGTTTCCATTCTTCCTATGGCGGGGTGTTTCTCTGGTGTGGGACGCAGTGGAGGGATGC AGGTGGTGTCCTTGGCACCCACTTGTCTCCGGAAGGGCCGAGGCATTGTCCTACATGAGCTCATGCACGT ACTTGGCTTCTGGCATGAGCATTCACGGGCAGATCGGGACCGCTACATCCAAGTCAACTGGAACGAGATC CTCCCGGGCTTTGAAATCAACTTCATCAAGTCACGGAGTACCAATATGTTAGTTCCCTATGACTACTCAT CTGTGATGCATTATGGGAGATTTGCCTTCAGCTGGCGTGGGCAGCCCACCATCATACCACTCTGGACCTC CAGTGTTCACATTGGCCAGCGATGGAACCTGAGTACCTCAGATATCACCCGGGTCTGCAGGCTGTATAAC TGCAGCCGGAGTGTCCCTGACTCCCACGGGAGAGGGTTTGAGGCCCAGAGTGATGGAAGCAGCCTCACCC CTGCCTCTATATCACGTCTACAAAGACTTCTCGAGGCACTGTCAGAGGAATCTGGAAGCTCTGCCCCTAG TGGCTCCAGGACTGGAGGCCAGAGTATTGCCGGGCTTGGTAACAGCCAGCAAGGATGGGAGCATCCTCCT CAGAGCACATTCAGTGTGGGAGCCTTGGCAAGACCACCTCAGATGCTAGCCGATGCTTCAAAATCGGGGC CTGGAGCAGGTGCAGACAGCTTGTCTCTAGAGCAGTTCCAGCTAGCCCAGGCCCCCACTGTACCTCTTGC TCTATTTCCAGAAGCCAGAGACAAGCCAGCACCTATCCAAGATGCCTTTGAGAGGCTAGCTCCACTTCCA GGAGGCTGTGCACCTGGAAGTCACATTAGAGAGGTGCCCAGAGAC

ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. View online » ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 1 / 3 Astl (NM_001291003) Mouse Tagged ORF Clone – MR229894

Protein Sequence: >MR229894 representing NM_001291003 Red=Cloning site Green=Tags(s)

MGIMGSLWPWILTMLSLLGLSMGAPSASRCSGVCSTSVPEGFTPEGSPVFQDKDIPAINQGLISEETPES SFLVEGDIIRPSPFRLLSVTNNKWPKGVGGFVEIPFLLSRKYDELSRRVIMDAFAEFERFTCIRFVAYHG QRDFVSILPMAGCFSGVGRSGGMQVVSLAPTCLRKGRGIVLHELMHVLGFWHEHSRADRDRYIQVNWNEI LPGFEINFIKSRSTNMLVPYDYSSVMHYGRFAFSWRGQPTIIPLWTSSVHIGQRWNLSTSDITRVCRLYN CSRSVPDSHGRGFEAQSDGSSLTPASISRLQRLLEALSEESGSSAPSGSRTGGQSIAGLGNSQQGWEHPP QSTFSVGALARPPQMLADASKSGPGAGADSLSLEQFQLAQAPTVPLALFPEARDKPAPIQDAFERLAPLP GGCAPGSHIREVPRD

TRTRPLEQKLISEEDLAANDILDYKDDDDKV

Restriction Sites: SgfI-MluI Cloning Scheme:

Plasmid Map:

ACCN: NM_001291003

This product is to be used for laboratory only. Not for diagnostic or therapeutic use. ©2021 OriGene Technologies, Inc., 9620 Medical Center Drive, Ste 200, Rockville, MD 20850, US 2 / 3 Astl (NM_001291003) Mouse Tagged ORF Clone – MR229894

ORF Size: 1305 bp

OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. RefSeq: NM_001291003.1, NP_001277932.1 RefSeq Size: 2261 bp RefSeq ORF: 1308 bp Locus ID: 215095 UniProt ID: Q6HA09 MW: 47.9 kDa Gene Summary: Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding.[UniProtKB/Swiss-Prot Function]