Anti-ST6GAL1 Monoclonal Antibody, Clone LN-1 (CABT-52011MH) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-ST6GAL1 monoclonal antibody, clone LN-1 (CABT-52011MH) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse anti Human CD75s antibody, clone LN-1 recognizes the human CD75s cell surface antigen, an alpha2,6 - sialylated carbohydrate epitope expressed by mature B cells (especially germinal centre B cells), red blood cells and some epithelial cells.

Specificity CD75s

Immunogen Human lymphocytes and SU-DHL4 cell line

Isotype IgM

Source/Host Mouse

Species Reactivity Human, Mink, Pig

Clone LN-1

Conjugate Unconjugated

Applications IHC-Fr; FC; IHC-P

Format Purified IgM - liquid

Size 100 μg

Preservative See individual product datasheet

Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.

Warnings For research purposes only

GENE INFORMATION

Gene Name ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 [ Homo sapiens (human) ]

Official Symbol ST6GAL1

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Tel: 1-631-624-4882 Fax: 1-631-938-8221 1 © Creative Diagnostics All Rights Reserved Synonyms ST6GAL1; ST6 beta-galactosamide alpha-2,6-sialyltranferase 1; ST6N; SIAT1; ST6GalI; beta- galactoside alpha-2,6-sialyltransferase 1; ST6Gal I; alpha 2,6-ST 1; B-cell antigen CD75; sialyltransferase 1 (beta-galactoside alpha-2,6-sialyltransferase); CMP-N-ac

Entrez Gene ID 6480

Protein Refseq NP_003023

UniProt ID P15907

Chromosome Location 3q27-q28

Pathway Asparagine N-linked glycosylation; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein; Defective ALG1 causes ALG1-CDG (CDG-1k); Defective ALG11 causes ALG11-CDG (CDG-1p); Defective ALG12 causes ALG12- CDG (CDG-1g); Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS); Defective ALG2 causes ALG2-CDG (CDG-1i); Defective ALG3 causes ALG3-CDG (CDG-1d);

Function beta-galactoside alpha-2,6-sialyltransferase activity; sialyltransferase activity;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]