165th OMICS Group Conference

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Accepted Abstracts (Oral)

Obesity-2013 Page 109 Eric Doucet et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

The maintenance of energy balance is compromised after weight loss Eric Doucet1, Jennifer L. Reed1,2, Jean-Philippe Chaput3 and Angelo Tremblay4 1University of Ottawa, Canada 2University of Ottawa Heart Institute, Canada 3Children’s Hospital of Eastern Ontario Research Institute, Canada 4Laval University, Canada

vailable literature reveals that of the majority of individuals who are able to lose weight, only a small number are able to Amaintain their weight loss over time. Effective weight maintenance strategies after weight loss are illusive, which is most likely the result of a number of yet poorly understood factors. In fact, both appetite and energy expenditure are profoundly altered in response to reductions in body energy reserves. Weight reduction leads to decreased energy needs, but to an augmented drive to eat, thus compromising the maintenance of energy balance in the weight-reduced state by widening the theoretical gap between the 2 components of energy balance. This review first provides a summary of the factors related to the control of feeding and energy expenditure during weight stability. More specifically related to the topic of this review, the bulk of the literature presented depicts the post weight-loss control of appetite and energy expenditure. The integration of the literature presented in this paper reveals that body weight loss seems to orchestrate a coordinated response to resist further energy depletion, which would seem to create a state of increased vulnerability of weight regain. It is argued that these changes are largely responsible for the more than apparent difficulty in maintaining weight maintenance after weight loss.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 110 Debra Shea, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Non-dieting approaches to weight management Debra Shea Speak 4 Health, USA

he prevalence of restrictive dieting and eating disorders continues to rise as do the rates of obesity. Despite billions of dollars Tspent annually in the US alone in the private weight loss industry the majority of individuals are unable to achieve long-term weight loss. Many report high levels of dissatisfaction with their lives and bodies. Non-dieting approaches, such intuitive eating and mindful eating, call for a paradigm shift from traditional weight loss strategies to combat obesity. Non-dieting approaches have been statistically and clinically associated with improvements in BMI, physiological measures (e.g., blood pressure, blood lipids), health behaviors such as eating and activity habits, and improvements in self-esteem and body image.

Biography Debra is a Registered Dietitian and holds a degree in Clinical Nutrition from Loma Linda University. She also holds a specialty certificate in Adult Weight Management from the Academy of Nutrition and Dietetics. Currently, she is CEO of the company Speak 4 Health. At Speak 4 Health she is not just another weight loss speaker. She has dedicated her career to women who struggle with their self-esteem and body image gain greater confidence in themselves. She has been an adjunct professor and College of the Desert in California. Her greatest love is helping women become a size Healthy versus Hollywood.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 111 Chesinta B. Voma et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Magnesium regulates reticular NADPH production in the hepatocyte; Possible implications of magnesium in and obesity onset Chesinta B. Voma1,2 and Andrea Romani2 1Cleveland State University, USA 2Case Western Reserve University, USA

he current western diet is approximately 35% deficient in magnesium (Mg2+). Magnesium deficiency has been correlated with Tthe onset and progression of several pathological conditions including diabetes, and obesity. As opposed to other clinical electrolytes, Mg2+ is not given the same attention clinically due to the poor understanding of its homeostasis. The hormonal regulation of magnesium has not been fully elucidated, and we continue to interpret the serum concentrations relative to urinary Mg2+ excretion. Also, our understanding of the extra- and intra-cellular role of Mg2+ is further complicated by the fact that the principal reservoir of Mg2+ (i.e., the bone) are not readily exchangeable with circulating Mg2+ in the extracellular fluid space. Thus, in states of a negative Mg2+ balance, initial losses come from the extracellular space since equilibrium with bone stores does not begin for several weeks. The long term goal of this research is to elucidate the implications of magnesium deficiency for liver and whole body metabolism. Our laboratory has previously reported that Mg2+ deficiency increases G6P transport into the liver ER, and its hydrolysis by G6Pase. The study reported here evaluates the role of Mg2+ deficiency on G6P conversion by Glucose-6-Phosphate Dehydrogenase (G6PD), the other intrareticular metabolic pathway for G6P, and its connection with 11β-Hydroxysteroid Dehydrogenase 1 (11β-HSD1), the NADPH-dependent enzyme responsible for the conversion of cortisone to cortisol. Both enzymes have been implicated in diabetes and obesity onset and progression. The results reported here validate our working hypothesis that a deficiency in hepatic Mg2+ content enhances the activities of both G6PD and 11β-HSD1within the lumen of the hepatic endoplasmic reticulum. Methods: Minimal deviation hepatocellular carcinoma cell line (HepG2-C34) were grown in media containing 0.2 mM, 0.4 mM (deficient) and 0.8 mM (physiological) [Mg2+] acutely (i.e. 5 days), and analyzed for NADPH production by fluorescence detection (350 nm excitation; 460 nm emission). NADPH production was induced by addition of varying concentrations of glucose 6-phosphate to digitonin-permeabilized cells. G6PD, G6Pase, and 11β-HSD1 expression levels were analyzed by western blot analysis for up- or down-regulation following Mg2+ deficiency onset. Production of cortisol from cortisone as a measure of the activity of 11β-HSD1 was analyzed by reversed phase HPLC. Results: NADPH production increased by ~60% under conditions of Mg2+ deficiency compared to cells presenting physiological levels of Mg2+, and resulted in a marked increase in cortisol production through 11β-HSD1 activity. Conclusion: Deficiency in Mg2+ appears to upregulate the utilization of G6P by G6PD for energetic purposes, with increased synthesis of NADPH. In turn, the increased level of intrareticular NADPH will favor the conversion of cortisone to cortisol. Increased cortisol production can explain – at least in part- the insulin resistance observed in several diabetic and/or obese conditions. Validation of these results in human patients represents the next step in our studies.

Biography Chesinta B. Voma is a doctoral student in Bioanalytical and at Cleveland State University. Her thesis research is being conducted at Case Western Reserve University, Cleveland, OH. In addition to her academic pursuit, she works as an ASCP certified medical technologist in a community based hospital laboratory and at an emergency department laboratory of a privately-owned hospital. She is a member of American Association for Clinical Chemistry, The Obesity Society and the Endocrine Society. Her research interest is focused on discovery of new biomarkers that will facilitate early identification and diagnosis of metabolic diseases.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 112 Otobrise Elohor Susan, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

The causes and medical and physical of obesity Otobrise Elohor Susan Tolu-Medical Centre, Nigeria

ccording to the findings, history taking reveals that in most patients, the presentation of obesity is straight forward with the Apatient indicating problems with weight or repeated failure in achieving sustained weight loss. In other cases, however, the patient may present with complications and/or associations of obesity. A full history must include a dietary inventory and an analysis of the patient’s level. Screening questions to exclude severe or untreated depression are vital because depression may be a consequence or a cause of excessive dietary intake and reduced activity because almost 30% of patients who are obese have eating disorders, screen for these in the history. The possibility of bingeing, purging, lack of satiety, food seeking behavior, night eating syndrome, and other abnormal feeding habits must be identified because management of these habits is crucial to the success of any weight – management program. When taking the history, the clinician should investigate whether other members of the patient’s family have weight problems, inquire about the patient’s expectations and estimate the patient’s level of motivation. The clinician should also determine whether the patient has had any of the co-morbidities related to obesity. In the clinical examination, measure anthropometric parameters and perform the standard, detailed examination required in evaluating patient with any chronic, multisystem disorder such as obesity. Waist and hip circumference are useful surrogates in estimating the clinical risk over time. Neck circumference is predictive of a risk of sleep apnea and its serial measurement in the individual patient is clinically useful for risk stratification.

Biography Otobrise Elohor Susan was born and brought up in the city of Lagos Nigeria. In 2007, she has gained admission into the school of Nursing Baptist Medical Centre (BUTH) Ogbomosho, Oyo State, Nigeria, where she was certified “Registered Nurse (RN)” in the year 2010. After school, she got her first appointment to work at a private hospital as a Registered Nurse in January 1st 2011 (St Louise Medical centre) Apapa, Lagos State. In May 3rd 2012 she has got another offer to work as a Nursing-Sister at Tolu- Medical centre, Lagos State, till date. Her future aspiration is to further more on the Nursing profession through continuing education.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 113 Mahendra Narwaria, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Co-morbidities resolution and quality of life after bariatric among elderly population: Results in 50 Indian geriatric patients Mahendra Narwaria Asian Bariatrics & Cosmetics Pvt Ltd., India

Introduction: Role of bariatric surgery in elderly patients remains controversial. As the number of morbidly obese elderly population is on the rise, we need standardized management strategies and evaluation of outcomes of surgical management in this population. Here, we present our experience in treatment of morbidly obese Indian population. Methods: Retrospective analyses of bariatric procedures done at our centre on patients aged 60 years and above from January 2009 through December 2012 were done. The percentage of excess weight loss, resolution of comorbidities and quality of life were analyzed. Results: A total of 50 patients aged >60 years who underwent bariatric surgery were selected. 29 patients underwent LSG, 19 patients underwent RYGB & 2 patients underwent mini gastric bypass. The mean age of the patient was 63.38 years (range 60- 73). The mean preoperative weight was 108.25 kg (range 69.10 – 167) and preoperative body mass index was 43.04 kg/m2 (range 30.71-75.22). The percentage of excess weight loss at 6 months, 1, 2 and 3 years were 42.1%, 76%, 82% and 86% respectively. At 6, 12, 24 and 36 months follow-up, 58.5% (n = 50), 95.1% (n = 37), 100% (n = 27) and 100% (n = 10) of patients achieved at least 50% EWL respectively. Resolution of diabetes mellitus occurred in 95% of patients, while the remaining 5% were on reduced dose of oral medications only irrespective of whether they are on insulin or OHAs preoperatively. Discontinuation of medications for hypertension was noted in 86% of patients and remaining patients were on reduced dose of anti-hypertensives. In the quality of life survey, 90.3% of patients reported very good or good quality of life after surgery. Mean duration of hospital stay was higher than our patients in younger age group (3.19 days) with a range between 2 to 5 days. There was no mortality in our patients. Conclusion: In our experience, bariatric procedures can safely be done in elderly populations with resolution of co-morbidities and improved quality of life in majority of them.

Biography Mahendra Narwaria obtained his master’s in Surgery from BJ Medical College, Gujarat University, Ahmedabad in 1996. Subsequently, he pursued his interest in Surgical at (SGPGI), Lucknow. His perpetual drive for excellence and up-gradation of skills, prompted him to take up 'Bariatric Surgery' and till date has performed more than 2000 bariatric procedures. He is the chairman of Asian Bariatrics Pvt. Ltd, Ahmedabad, India. He is guest editor to Journal of Video-Surgery (Poland) and was past president of Obesity & Metabolic Surgery Society of India (OSSI). He also served as founder treasurer & secretary of OSSI and founder president of Association of Ahmedabad Surgeons (AAS). He has performed more than 100 live demonstrations for surgeons during different conferences in India and abroad and organized more than 20 national and international conferences. He is a visiting consultant at Apollo International Hospital Ahmedabad, Artemis Hospital, Gurgaon and Seven Hills Hospital, Mumbai. He is a teaching faculty at Ethicon Institute of Endosurgery, India and Center of Excellence in Minimal Access Surgery Training (CEMAST), Mumbai, India.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 114 Ronaldo C. Araujo, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Modulation of immune system cells from induced by exercise and caloric restriction in obese mice Ronaldo C. Araujo Federal University of São Paulo, Brazil

uring obesity establishment, immune cells resident in adipose tissue become important as sources of pro-inflammatory Dmediators. Exercise and caloric restriction are important non-pharmacological tools against body mass increase and are poorly investigated concerning their effects on immune cells of adipose tissue in obese organisms, especially when a high fat diet is consumed. Thus, after a previous period of high fat diet consumption, mice were submitted to chronic swimming training or 30% caloric restriction in order to investigate the effect of both interventions on immune cells resident in adipose tissue. Our results demonstrated that both exercise and caloric restriction were able to reduce body mass in animals consuming high fat diet. However, in general, such strategies induced different chances in the numbers of immune cells resident in adipose tissue or in serum cytokines/chemokines produced by mice in a fat diet regimen. Specifically, exercise was able to increase NK number in adipose tissue and serum levels of IL-6 and RANTES while caloric restriction increased CD4/CD8 ratio and increased MCP-1 levels. Together, these data suggest that body mass reduction is not the only prerequisite to determine the effects of exercise or caloric restriction and reinforce the idea that the combination of both strategies is better than their single utilization. We also investigated the role of leptin in these parameters using the leptin deficient mice (ob/ob) after swimming protocol. We observed that exercise didn’t affect the food intake, body weight as well as immune cells of adipose tissue in ob/ob mice, highlighting the leptin role in exercise and in adipose tissue inflammation.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 115 Ioan Chirila et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Using meal replacement and physical activity for weight management Ioan Chirila1, 2 and Vasile Drug1, 3 1University of and “Grigore T. Popa”, Romania 2National Institute of - RCoPH, Romania 3”Sf. Spiridon” University Hospital, Romania

se of meal replacements (MR) and physical activity (PA) seems to be effective weight-loss strategies both in the short and Ulong term in a clinical trial setting. Two longitudinal studies kept track of the nutritional parameters development within the weight loss programs based mainly on low-calorie diet using MR (MR group, 56 women and 23 men) and physical activity (PA group, 97 women and 46 men). In both samples, weight loss was significant, with an average of-10 to 11% of initial weight, but in different periods of time (on average 4 months to MR sample and 9 months to PA sample). The average weight loss was -2.7 kg/month in MR group and -0.8 kg/month in PA group, with higher values in men for both study groups. Percentage of excess weight loss was approximately 40%, and adherence to weight loss program was better for women in MR group and for men in PA group. The percentage of weight loss was significantly correlated with the length of weight loss program, but also with initial BMI. Replacing two meals a day was an effective way to lose weight because of its simplicity and convenience of use. The cost of the products and monotony of the diet were the main causes to abandon the diet. Subsequently, keeping the obtained weight was better in the subjects replacing one meal a day with MR and in the people keeping a high level of PA.

Biography Ioan Chirila is a senior M.D. in the field of Preventive Medicine and has a master’s degree in Nutrition. He completed his Ph.D. this year in overweight management methods from University of Medicine and Pharmacy ”Grigore T. Popa” (Iasi, Romania), after a research mobility in the Department of Public Health from University of Szeged (Hungary). In 2010, he was nominated Practitioner of the Year: Preventive Medicine, for performance and dedication in medical profession (Young Doctors Awards) and he now works in National Institute of Public Health from Romania. He has published/ presented more than scientific 25 works.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 116 Valter Silva et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Weight loss management through exercise based on guideline recommendation: A case series from SRF-YMCA Study Valter Silva1, 2 and Antonio Jose Grande1, 2 1Universidade Federal de São Paulo, Brazil 2Brazilian Cochrane Centre, Brazil

n order to preserve and improve the health status of individuals, we proposed the study project SRF-YMCA (surveillance of risk Ifactors for chronic diseases in YMCA members). Thus, the objective of this study was to analyze the weight loss management through exercise based on ACSM/AHA guideline recommendation. We randomly evaluated 30 subjects (15 men and 15 women, aged between 26 and 48 years) from SFR-YMCA, performing a case series study. The exercise prescription was based on the ACSM/AHA current recommendations for health-related to physical activity. The outcomes studied were: total body mass (kg), body mass index (kg/m²), waist-to-hip ratio, waist circumference (cm), sum of peripheral skinfolds (mm), sum of central skinfolds (mm), body fat percentage (%), total fatness (kg), and lean mass (kg). The reassessment was conducted at six months after the beginning of exercise. To examine the responsiveness to the exercise, we estimated absolute and relative deltas values. For the statistical analysis, we used the Shapiro-Wilk test, Student t test, Wilcoxon test and Mann-Whitney U Test (p≤0.05). The exercise based on the ACSM/AHA guideline recommendation for weight loss management was effective. Significant changes and tendencies to improvements occurred in components of body composition (e.g., fat reduction and lean mass increase) for both genders. In addition, it was found that men generally have better responsiveness than women do.

Biography Valter Silva is a Professor of Evidence-Based Medicine in the Federal University of São Paulo, researcher in the Brazilian Cochrane Centre and member of the Board of Postgraduate and Research in the Federal University of São Paulo. He has working as a peer-reviewer in journals like BMJ. The main fields of interest are related with research methods and statistics, systematic review and meta-analysis, evidence-based health and physical activity for chronic noncommunicable diseases.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 117 Sumeet Gullaiya, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Anti-obesity potential of isolated demethoxycurcumin against high fat diet induced obesity in albino wistar rats Sumeet Gullaiya Amity University, India

s obesity has become a major lifestyle health problem in the world, the present study was designed to investigate the possible Aanti-obesity and hypolipidemic effect of demethoxycurcumin (DMC), a bioactive phenolic component of turmeric spice, for the first time, usingin vivo anti-obesity models and to explore the linking mechanism behind it by evaluating bodyweight, food intake, lipid profiles, renal, hepatic, cardiac function markers, lipid peroxidation, and the glucose and insulin levels in blood and liver tissue in rats. Rats (80-100 gms) were divided into 4 groups with n=6. Group 1 served as control and was fed with normal diet. All other animals were treated with high fat died for 14 continuous weeks which was followed by its equal distribution in three equal groups. Group 2 received HFD with no supplement; Group 3 received DMC (20 mg/kg) + HFD. DMC was started administered at 10th week from the start time for the treatment. Group 3 received DMC (40 mg/kg) + HFD. Body weight, lipid profile & renal function (urea, uric acid creatinine) ALT & AST activities, cardiac markers, (LDH, C.K- NAC and MB) the oxidative stress marker reduced glutathione (GSH), and malondialdehyde (MDA) catalase activity, in addition to glucose, insulin, and insulin resistance in serum & tissues were analysed. Results revealed that HFD significantly increased final body weight, triglycerides (TG), total cholesterol, & LDL concentration compared with controls. DMC treatment significantly improved obesity and its associated metabolic problems in different degrees in experimental animals proving its distinct anti-obesity effect.

Biography Sumeet Gullaiya has completed his Ph.D. (Pharmacology) at the age of 29 years from Delhi Institute of Pharmaceutical Sciences and Research, University of Delhi, India. He is working as assistant Professor in Amity University, a premier research oriented academic organization. He has published more than 15 papers in reputed journals of national and international repute. He is also serving as an editorial board member and reviewer for reputed journals.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 118 Nupo S. Sedodo et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Dietary diversity score and nutritional status of undergraduates in South West Nigeria Nupo S. Sedodo1, Akinlotan J. V1, Akinlua O1, Olunusi P. Abosede2, and Oguntoyinbo S. Isaac1 1Moshood Abiola Polytechnic, Nigeria 2Tai Solarin University of Education, Nigeria

Background: This study was carried out to assess the dietary diversity score (DDS) and nutritional status of undergraduates students in south west Nigeria. Methods: A representative sample of two thousand (2000) undergraduate students was surveyed from two Nigerian Polytechnics using simple random technique. A pretested interview guide was used to collect information. Information on dietary diversity was obtained using Food and Nutrition Technical Assistance Project questionnaire (FANTA). Body mass index (BMI) according to WHO classification was used in classifying nutritional status. Information on food intake was obtained from 24-hour dietary recall techniques. Dietary diversity score (DDS) was computed and the nutritional status was assessed. Data were analyzed using descriptive statistics; SPSS software package version 16.0. Results: The result of the BMI showed that 3% of male students were underweight, 46% of male students had normal weight, 5% of the female were overweight while 2% of the female students were obese. DDS of the subjects showed that cereals and grain group consumed by male was 0.40±.01a while female scored 0.43±0.2a, seeds, nuts and legumes consumed by male were 0.53±.11a while female had 0.52±0.1a score. Mean score of starchy, roots and tubers consumed by male and female were 0.63±0.2a and 0.67±0.9a respectively, vegetables group for male were 0.63±0.23b while female had 0.66±0.3b, of the fruits group 0.50± 0.2a was scored by male while female scored 0.56±0.17b, out of the meat and meat products scored male scored 0.17±0.3a while female had 0.21±0.3b, mean of the fish and sea foods shows that male scored 0.60±0.b while female scored 0.86±0.2a. Oil and dairies group shows that male scored 0.61±0.5a while female scored 0.62±0.9a. The total dietary diversity score for male was 4.07±1.84a while female had 4.53±3.07a. DDS of male were higher than female (P < 0.05). The dietary diversity terciles revealed that the male and female scores were within the low tercile (1-4). Conclusion: The subjects had low DDS with few students malnourished.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 119 Magdy Elsharkawy et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Influence of obesity on post renal transplanted patients Magdy Elsharkawy, EssamKhedr, Ahmed Abdel Kader, Dalia Farag, Hewayda El Shennawy, Hesham El Sayed and Medhat Ali Ain Shams University, Egypt

Introduction: Obesity has long been regarded as risk factor in general surgical procedures; investigations have been carried out evaluating the risks associated with obesity in renal transplantation. The aim of this work was to study the following: The incidence of obesity (BMI>30) among Egyptian transplant patients, body weight variation within the first year of transplantation and impact of obesity on the following: (Immunosuppressants (cyclosporine A level and steroids), surgical and post-operative complications, short term graft outcome and biochemical changes like blood sugar, leptin and lipid profile). Patients and Methods: This study included 100 live donor kidney transplant recipients. Patients were subdivided according to their calculated BMI where, 42 (42 per cent) were non-obese (Group I) (BMI=18.5-24.9/Kg/m²), 19 (19 per cent) were over-weight (Group II) (BMI=25-29.9/Kg/m²) and 39 (39 per cent) were obese (Group III) (BMI= >30/Kg/m²) prior to transplantation. All patients were subjected to full medical history and clinical examination, BMI, triceps fold measurement, ECG and echocardiography, post-transplantation variables were collected at three, six and 12 months which included weight, blood cyclosporine, total serum cholesterol, triglycerides, HDL and LDL blood glucose, blood urea, serum creatinine, sodium, potassium, calcium, phosphorus, total and direct bilirubin, AST, ALT, alkaline phosphatase, and leptin level. Renal graft biopsy whenever indicated. Results: In the current study, operative and post-operative surgical complications occurred more frequently among obese recipients, yet there was no statistically significant difference in the incidence of operative and post-operative surgical complications, operative duration or hospitalization between the three groups. A highly significant difference was regarding the amount of weight gain between the obese group and each of the overweight and non-obese groups. The obese group required higher doses of CsA per kilogram of body weight, than the overweight and non-obese groups until the 3rd month but after the 3rd month, the obese group required the lowest CsA doses per kilogram of body weight among the three groups in order to maintain the desired trough cyclosporine levels. Significant differences were noticed in systolic blood pressure levels by ANOVA test between the three groups at the 6th and 12th months after renal transplantation; the difference mainly detected between the non-obese and obese groups. There was a tendency toward rise in blood lipids in the three groups after surgery with a higher incidence among the obese and overweight groups. Leptin levels were also found to reach higher levels among the obese group. Co relational analyses one year post-transplant showed highly significant positive associations between leptin levels and BMI in our study population, We have noticed, higher fasting blood glucose levels in the obese when compared to the overweight and non-obese groups, even though the difference was not significant and a significant difference between the groups as regard to the total number of patients requiring anti-diabetic 1 year post-transplant which was equal to 24 (61%), 6 (31%) and 12 (29%) in the obese, overweight and non-obese groups, respectively. There was however no statistically significant difference between the 3 groups as regards the incidence of graft rejection; Graft survival or patient survival. Conclusion: The commonest surgical adverse effect of having a BMI greater than 30 kg/m² was an increase in the incidence of wound infection and dehiscence. The commonest medical adverse effects of having a BMI greater than 30 kg/m² prior to renal transplantation were in the form of higher incidences of weight gain, systolic hypertension, hyperlipidemia and post transplant DM. Obese renal transplant recipients usually receive similar doses of immunotherapeutic drugs as non-obese recipients, where no special dose adjustment is necessary as regard MMF and azathioprine, yet obese patients require higher initial doses of CsA, and also require higher doses of steroids. Acute rejection episodes seem to occur at a higher incidence among the obese, yet the difference is not significant. A substantial proportion of transplant patients experience a marked increase in body weight following transplantation and obesity remains a significant cause of diabetes and cardiac complications. No significant difference is noticed in graft or patient survival with variation of BMI.

Biography Magdy ElSharkawy completed his M.D. in 1988 and Ph.D. in 1998, and postdoctoral studies from Ain-Shams School of Medicine. He was the director of unit from 2002 to 2010, Ain-Shams University Hospitals, and now the director of Dialysis unit, Nasser Institute (200 patients). He has published more than 35 papers in reputed journals (national and international), and presented several studies in international conferences, and serving as reviewer in several international journals. He is a working member in the ISN, ASN, ERA-EDTA, and board member of ESNT.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 120 Bhanu K. Patibandla, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Obesity- The big problem Bhanu K. Patibandla St. Vincent Hospital, USA

besity is from the Latin obesitas, which means "stout, fat, or plump". Medically, obesity is known as a condition in which Oexcess body fat has accumulated to the extent that it may have an adverse effect on health, leading to reduced life expectancy and/or increased health problems. People are considered obese when the body mass index (BMI) exceeds 30 kg/m2. It has become a global epidemic affecting approximately 1.5 billion adults, and costing 150 billion dollars of health economy. It is a more common and rapidly growing problem in the United States of America (USA); the average weight of an adult worldwide is 62 kg while in the USA it is 80 kg. Though increased calorie intake, and sedentary life style has been majorly attributed to explain most cases of obesity, the other factors that should be considered in the differential include endocrine disorders, psychiatric illness, medications, genetics, and infectious agents. The United States Preventive Services Task Force recommends screening for all adults followed by behavioral interventions (Grade B recommendation) in those who are obese. It is considered important to intervene because obesity is one of the leading preventable causes of death worldwide. On average, obesity reduces life expectancy by six to seven years, a BMI of 30–35 kg/m2 reduces life expectancy by two to four years, while severe obesity (BMI > 40 kg/m2) reduces life expectancy by ten years. Public health efforts seek to understand and correct the environmental factors responsible for the increasing prevalence of obesity in the population. The main treatment for obesity consists of dieting and physical exercise. Ideal initial plan should be to lose 5-10% of body weight (1-2 lb per week) using combination of diet, physical activity, and behavioral techniques which include but not limited to self control, weight tracking, stimulus control, and group support. In case of failure to lose weight with following the above plan for at least six months, medical management is indicated for BMI>30 kg/m2 or 27 kg/m2 plus comorbidities. Drugs FDA approved for weight loss are Orlistat (Xenical), Locaserine (Belviq) and a combination of Phentermine and topiramate (Qsymia); Sibutramine is recently withdrawn due to cardiovascular side effects. The most effective treatment for obesity is bariatric surgery. However, due to its cost and the risk of complications, it is currently indicated for the patients with BMI >40 kg/m2 or 35 kg/m2 plus comorbidities. In summary, obesity management includes early intervention with dietary restrictions, and regular exercise; medical and surgical interventions with long term follow up are appropriate in certain BMI cohorts and/or when the prior management plan fails.

Biography Bhanu K. Patibandla has obtained MBBS from Dr. NTR University of Health Sciences, India in 2010. The evidence based clinical practice and the scope for the research opportunities in the United States attracted him to pursue his further career in the USA. He worked as a post doctoral research fellow (2/2011 to 2/2012) at Beth Israel Deaconess Medical Center and Harvard , Boston in the division of nephrology. His primary areas of interest include identifying the various disparities involved in the provision of health care. He has published in the field of dialysis access, renal transplantation, and effects of BMI and comorbidities on access to renal transplantation in the diabetics. Currently, he is doing residency training at St. Vincent Hospital, Worcester, MA.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 121 Helaine Ciporen, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

An internet solution for families at risk for obesity and diabetes: Online intervention and curriculum to train healthcare workers developed by Mount Sinai Medical Center and Columbia University Helaine Ciporen Mount Sinai Medical Center, USA

unique partnership between Mount Sinai Medical Center’s Pediatric Diabetes Department, Columbia School of Social Work Aand the Columbia Center for New Media Teaching and Learning has resulted in ‘diaBeaters!’, a multi-session, interactive, online program to help mothers and caregivers establish the lifestyle changes needed for the prevention and management of obesity and type 2 diabetes in their children and families. The internet capabilities of this program holds the promise of cost effective distribution, usage and training capabilities for professional and community health workers via webinar conferencing. The patient-centered, interactive approach of the intervention makes it adaptable to the needs of various cultures and resources. Launched in 2010, ‘diaBeaters!’ Prompts families to reflect on their current behaviors, assess their needs and resources, and develop customized plans to meet their unique needs. Following the CDC’s evidence based recommendation for multisession healthcare counseling, this program adds motivational counseling interventions to overcome psychosocial barriers and progress through the hierarchy of stages of change, including relapse. Through interactive games and activities, ‘diaBeaters!’ enhances a family’s engagement in health education, promotes their investment in creating and implementing self-made plans, strengthens their development of problem solving skills and builds self efficacy. ‘diaBeaters!’ has a built-in capacity to train new and existing healthcare workers through webinar education and provide ongoing support with its detailed curriculum guide. At Columbia University, students in the advanced clinical practices social work courses use ‘diaBeaters!’ effectively to both learn about diabetes and analyze various clinical skills to enhance their practice. The teaching guide provided for every page of the intervention educates and supports the practitioner. To quote one student, “I think my biggest take-away from the diaBeaters! Intervention is seeing how closely connected these elements of health, social work, and psychosocial work are.” The process of developing ‘diaBeaters!’ reflects a contemporary shift towards meaningful collaboration among researchers, direct service providers, and communities to be targeted for intervention.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 122 J. Renae Norton, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

The Food pollution/addiction model for treating eating disorders and obesity: A systems approach J. Renae Norton The Norton Center for Eating Disorders and Obesity, USA

he U.S. has the distinction of being the unhealthiest wealthy country in the world, with the most obese population. In a recent Treport commissioned by the National Institutes of Health (NIH) to study the relentless decline in the health of Americans, the U.S. was compared to 16 other wealthy nations. The U.S came in dead last having the highest overall mortality rate. The epidemic of obesity and its complications plays a significant role in driving higher mortality rates. The common denominator in the relentless decline in the health of Americans is the U.S diet. The root cause of these problems is the pollution of the American food supply by the agribusiness, biotech and food industries. Additives that have been shown to be carcinogenic, neurotoxic, obesogenic, and addictive, commandeer parts of the brain that serve the functions of survival, making them resistant to treatment. Thus, obesity is best treated taking into consideration the role that addiction plays. Treatment outcomes for obesity improve dramatically when patients are taught the difference between clean versus polluted eating. Given the current obesity epidemic, a model is needed that will also lead to prevention. The food pollution/addiction model does just that. Empirical data will be presented in conjunction with case studies to bring these concepts home for the practicing or teaching professional.

Biography J. Renae Norton is trained as a Family Systems Psychologist with a focus on eating disorders and neuropsychological assessment. She is also a published author. She has released two lifestyle books for children, How Maji Gets Mongo off the Couch and Maji Helps Maji Learn How to Eat Clean. She has been working on a new book, Cycles of Shame, to be released this year on Food Pollution/Addiction as it relates to the obesity epidemic and the escalation of ED’s in the US.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 123 Amy Brown, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Early influences on child weight and eating style: The role of a baby-led weaning style Amy Brown Swansea University, UK

hildhood obesity continues to be a critical problem. Ability to be ‘satiety responsive’ and balance intake of energy to need is Can important element of maintaining a healthy weight. Research has shown that experiences during infancy may have a long- term impact upon weight gain and eating style. Breastfeeding and delayed introduction of solid foods are associated with lower risk of obesity. However research has not explored the impact how infants are introduced to solids upon child weight. Traditionally infants are introduced to solid foods via spoon-feeding of purees. However baby-led weaning advocates allowing infants to self-feed foods in their whole form. Advocates suggest it may promote healthy eating styles but empirical evidence examining the method is sparse. The aim of the current study was to compare child weight and eating behavior at 18-24 months for infants weaned following a traditional weaning approach compared to a baby-led weaning style. 298 mothers completed a longitudinal questionnaire exploring infant nutrition when their infant was 6–12 months and again at 18–24 months. At 6–12 months mothers reported weaning style (bay-led versus traditional), breastfeeding duration and timing of introduction to complementary foods. At 18–24 months, mothers reported child-eating behavior (satiety responsiveness, food responsiveness, fussiness, enjoyment of food). Infants weaned using a baby-led approach (n=163) were significantly more satiety responsive and less likely to be overweight compared to those weaned using a standard approach (n=135). This was independent of breastfeeding duration, timing of introduction to complementary foods, birth weight and maternal child-feeding style. A baby-led weaning approach may therefore encourage greater satiety responsiveness and healthy weight gain trajectories in infants. Explanations for the findings include greater infant control, flavor learning and participation in family meal times.

Biography Amy Brown is a Senior Lecturer in Public Health and Policy Studies at Swansea University, UK. Her research explores early influences upon weight and appetite regulation, particularly in relation to milk feeding and introduction to solid foods. She has published over twenty papers examining both the impact of these initial choices on later child weight and eating behavior and the factors affecting maternal decisions surrounding nutrition during infancy. Her work aims to explore ways of supporting new mothers to make informed and healthy choices for her infant during the early years.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 124 Claudio Santibañez, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Availability and characteristics of cardiovascular rehabilitation programs in South America Claudio Santibañez Mayo Clinic, USA

Purpose: Cardiac rehabilitation (CR) programs decrease morbidity and mortality rates in patients with coronary artery disease, the leading cause of death in Latin America. This study was carried out to assess the characteristics and current level of CR program implementation in South America. Methods: We carried out a survey of CR programs that were identified using the directory of the South American Society of and through an exhaustive search by the investigators. Results: We identified 160 CR programs in 9 of the 10 countries represented in the South American Society of Cardiology and 116 of those responded to our survey. On the basis of survey results from the responding programs, we estimate that the availability of CR programs in South America is extremely low, approximately 1 CR program for every 2 319 312 inhabitants. These CR programs provided services to a median of 180 patients per year (interquartile range, 60-400) and were most commonly led by cardiologists (84%) and physical therapists (72%). Phases I, II, III, and IV CR were offered in 49%, 91%, 89%, and 56% of the centers, respectively. The most commonly perceived barrier to participation in a CR program was lack of referral from the cardiologist or primary care , as reported by 70% of the CR program directors. Conclusions: The number of CR programs in South America appears to be insufficient for a population with a high and growing burden of cardiovascular disease. In addition, there appears to be a significant need for standardization of CR program components and services in the region.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 125 Veena Aggarwal et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Obesity- Osteoporosis link: A pilot study, connecting excess body fat and bone health status Veena Aggarwal and Ranjana Babber VLCC Healthcare Ltd, India

ccording to World Health Organization (WHO), osteoporosis is second only to cardiovascular disease, as a global healthcare Aproblem. Though various research studies had indicated the dominance of osteoporosis in older age group and post- menopausal, there are scientific signals connecting obesity associated factors -oxidative stress, elevated blood sugar level and metabolic disturbances with poor bone health. This research study was undertaken with the objective to ascertain excess body fat percentage as one of the common attribute to weak, porous bones and to develop a handbook providing practical solutions for prevention of osteoporosis in-pretext of present lifestyle. The bone density assessment was carried out for total of 180 subjects (84% female and rest 16 % male; age range- 20- 73 yrs), enrolled for weight management programme across 4 different VLCC wellness centers. The T score values, reflected poor bone health status for 41% of subjects under study-28.5% had osteopenia and the rest 12.5% with osteoporosis. These findings confirmed bone health deterioration not only in women subjects but in men as well.Mean age data for these groups- Normal bone health (36 years), Osteopenia (40 years) and Osteoporosis (48 years) entrenched on the age progressive nature of bone deterioration .In-depth view of data, further highlighted low bone mineral density at a relatively younger age–osteopenia & osteoporosis at 20 & 22 years respectively. The Body composition analysis (Bio-electrical Impedance) revealed a higher fat percentage (mean value-41.4%) against osteopenia and osteoporosis group in comparison to 38.9% in normal bone health group. Also, the prevalence of medical conditions as PCOS, hypothyroidism and CVD was 39% in osteopenia and osteoporosis group whilst 22% in normal bone health. The research findings, negated the myth that excess fat is protective for bones instead it substantiated the link that excess body fat creates unhealthy metabolic pathways, that disrupts bone matrix.

Biography Veena Aggarwal is an eminent scientist and researcher, and has bestowed her life in the advancement of nutrition science. An ex-consultant of Nutrition Foundation of India and USAID, she is known for her passionate alignment with the cause of health & wellness for all. She is also a member of Technical and Accreditation Committee of National Accreditation Board for Hospitals and Healthcare providers (NABH, Quality Council of India). She is a pioneer in the field of wellness and has been working for more than a decade in field of obesity management. As the Head to R&D, Technical & Training, VLCC Healthcare, she has evolved weight management as a scientific discipline and holistic care model. She has been instrumental in leading various research projects and written numerous manuals, health guides and knowledge papers. She has concluded efficacy study for many research trials for non-invasive body contouring technologies. Her present research study on DNA based diets for scientific weight loss shall help in providing information on the relationship of genetics for diet effectiveness.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 126 Jaimie N. Davis, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

LA sprouts: A garden/cooking/nutrition intervention is linked to decreased childhood obesity Jaimie N. Davis University of Texas, USA

he enormity of the problem of childhood obesity requires that effective, innovative prevention and intervention strategies Tbe developed for the future health and success of our Country. Recently, the formation of the first-ever US federal task force began to address this childhood obesity epidemic, with one of the key pillars being making healthy foods more affordable and accessible for families, and uses gardening as a primary vehicle to engage the public. However, few well-designed experimental studies exist that rigorously evaluate the impact of garden-based nutrition interventions on obesity and related metabolic disorders specifically in high-risk youth populations. The goal of this study is to conduct a school-garden-based randomized nutrition and gardening intervention, utilizing a garden built on school campus, lessons taught during and after school program and family workshops to improve dietary intake and reduce obesity and related metabolic disorders in Latino children (8-11 years). Two regions, each with two elementary schools (90% Latino) were randomized into either: 1) LA sprouts (12-week after school gardening/nutrition classes + bi-monthly family workshops; two schools, n=163 students); or 2) Control (delayed intervention; two schools, n=134 students). The intervention compared to the control group had significant reductions in BMI (-4% vs. +1%; P=0.007) BMI z-scores (-13% vs. -3%; P=0.008), and waist circumference (-2% vs. +1; P<0.001). The intervention compared to the control group also had significant improvements in dietary intake (i.e., vegetable and dietary fiber intake) and related dietary behaviors (i.e., preference, motivation, and self efficacy to eat fruits and vegetables).

Biography Jaimie N. Davis is an Assistant Professor in the Department of Nutritional Sciences, at UT-Austin. She has her Ph.D. in Nutritional Sciences and is a Registered Dietitian. Her research focuses on designing and disseminating nutrition, physical activity, and behavioral interventions to reduce obesity and related metabolic disorders in overweight minority youth. She has a strong background in nutrition, physical activity, body composition assessment, and metabolic testing in pediatric populations. She has written numerous papers examining the role that dietary intake, specifically added sugar and dietary fiber, plays on adiposity and metabolic profiles in overweight Latino children.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 127 James Lamper, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Obesity & weight loss in clinical practice: A nutritional-psychological-medical-social model James Lamper WeightMatters Practice, UK

he WeightMatters Practice in the heart of London’s medical district is a growing and thriving practice that uses a multi- Tfactorial model for the treatment of weight loss and obesity. The medical factors and current nutrition of a client are examined in context with their personal psychological and eating history, together with the relational context of their upbringing and their present day circumstances. Eating and behavioral therapists work with a cognitive-behavioral, psychodynamic and nutritional frame of reference to explore eating patterns and self-sabotage behaviors, supporting clients to build new strategies, skills and resources to lose weight and change their lifestyle. The wider team offers medical, psychiatric, dietetic and body work providing a holistic and robust support structure for clients who present with varying levels of eating, weight, food and body presentations. The talk will present the reasons why this model works, and how this can be a useful blueprint for other weight loss and obesity practices.

Biography James Lamper is an Eating and Behavioral Therapist and a leading UK authority in the treatment of all conditions associated with weight, eating, food and body image. His fresh, bright and enthusiastic personality make him an exciting presenter, industry consultant and media commentator. His knowledge and experience span over 25 years, with training in the fields of psychotherapy, counseling, nutrition and exercise. This gives James a unique ability to work holistically with any client, understanding how their mind, body and nutrition interact to manifest various eating conditions. His empathy and genuine openness allows him to connect with people, making his interventions and treatment so powerful. His passion and authority fuel his entrepreneurial flair. He is the founder of the prestigious WeightMatters Practice in central London; a leading centre that deals with the psychological, nutritional and medical treatment of eating, weight and body issues. New for 2013, he has launched Care For Your Weight, a search portal website that connects people who struggle with their weight with practitioners across the UK.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 128 Joseph L. Mahoney, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

The importance of organized out-of-school activities in developing obesity during childhood and adolescence Joseph L. Mahoney University of California, USA

his presentation overviews two longitudinal studies that identify common out-of-school care arrangements for children Tadolescents and examined whether those arrangements predicted subsequent obesity. The first study assesses after-school program (ASP) participation on child body mass index (BMI), obesity status, and indicators of peer acceptance over time. Participants were 439 children in grades 1-3 who resided in a disadvantaged, urban city in the Northeastern United States. Obesity status was defined as a BMI ≥95th percentile for age and gender. Children who were regular participants in ASPs showed a significantly lower increase in BMI over time and were less likely to be obese at follow-up than non-participants (21% and 33% respectively). Children who participated in ASPs also showed significant increases in popularity, received fewer peer nominations for rejection, and had larger peer networks compared to non-participants. All findings held after controlling for demographics. The second study involved participants from a nationally representative sample of 1,766 adolescents from the panel study of Income Dynamics-Child Development Supplement. Results showed that, beyond baseline measures of BMI before the summer and several demographic aspects known to predict obesity, youth whose summer arrangements involved regular participation in organized activities (sports, extracurricular activities, and after-school programs) showed significantly lower rates of obesity than other youth. This was most evident for youth whose activity participation was consistent across two waves of the study and for early adolescents. Youth whose regular summer arrangement was predominated by parent care without organized activity participation showed the highest rates of obesity.

Biography Joseph L. Mahoney is a Professor in the School of Education at the University of California, Irvine. Trained as a developmental psychologist, his research focuses on the developmental consequences related to how young people spend their out-of-school time. He earned his doctorate at UNC- CH (1997) and post-doctoral work at Stockholm University’s Psychological Institute (1999). He was as an Assistant and then Associate Professor of Psychology at Yale University (1999-2007). The author of over 50 articles, books, and chapters, he received SRCD’s Distinguished Congressional Policy Fellowship and served as lead education council for U.S. Senator Jeff Bingaman in 2011-2012.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 129 Jelena Vulevic, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Dietary modulation of gut microbiota in overweight individuals Jelena Vulevic The University of Reading, UK

ecent studies have shown that the gut microbiota varies in both its composition (e.g. reduced levels of bifidobacteria and Rincreased levels of less desirable bacteria) and its metabolic activity in obese individuals compared with lean individuals. It seems that microbiota can modulate host energy homeostasis and adiposity through a number of different mechanisms, including harvesting energy from food, lipopolysaccharide (LPS)-induced chronic inflammation, modulation of tissue fatty acid composition and gut-derived-peptide secretion. Modulation of the gut microbiota by dietary means is the basis for the probiotic and prebiotic concepts. The majority of scientific data on prebiotic effects comes from studies with either inulin-type fructooligosaccharides (FOS) or galactooligosaccharides (GOS). The capacity of these prebiotics to selectively stimulate the growth of bifidobacteria, and in some cases lactobacilli, and elicit a significant change in the overall composition of the gut microbiota has been demonstrated repeatedly. With regard to obesity and related metabolic disorders, the majority of available data related to prebiotics comes from animal models and dietary supplementation with FOS. These studies suggest that prebiotics are able to regulate food intake and weight gain, glucose homeostasis, dyslipidemia, steatosis and hypertension. However, one recent study looked at the effect of a unique second generation prebiotic GOS and found significant positive effects on microbiota, immune response and metabolic syndrome markers in overweight individuals. This presentation will aim to summarise the ‘obese microbiota’, its possible beneficial modulation through the use of prebiotics with the emphasis on the second generation prebiotic GOS.

Biography Jelena Vulevic has a Ph.D. in gut microbiology with 13 years research experience in the area of functional food ingredients at the University of Reading, United Kingdom. She has supervised number of undergraduate and postgraduate (both M.Sc. and Ph.D.) students, lectured on the variety of courses and presented at various seminars and conferences. The topics included microbiota, prebiotics, probiotics, omega-3-fatty acids, flavonoids, medical nutrition, etc. Currently she is employed as Medical Liaison Manager at Clasado Ltd.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 130 Le Thi Huong, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Overweight, obesity and associated factors among secondary school students in a Northern city of Vietnam in 2011 Le Thi Huong Hanoi Medical University, Vietnam

verweight and obesity is an emerging public health problem among school-aged children in Bac Giang city in the Northen Opart of Vietnam recently. This study aims to identify overweight- obesity prevalence of secondary school children in this city and its associated factors. The study was a nested case control in a cross-sectional study design in 1528 secondary students selected from 4 secondary schools in 2 inner communes and 2 suburban communes of Bac Giang city, Vietnam. Result: Overweight prevalence among secondary school students in Bac Giang was 6.7%, the prevalence of obesity was 2.0%. Overweight and obesity is more prevalent in male students, inner communes and students from family have higher income and higher food expense. Overweight and obesity was associated with higher energy intake, more fat consumption, having supplement meals and bedtime-meal, increased physical activities and increased sleep duration. Conclusion: Education campaign targeting reducing overweight and obesity should target both parents about dietary adequacy and balance and children about more physical activities.

Biography Le Thi Huong has completed her Ph.D. on Human Nutrition at Wageningen University, the Netherland in 2008. In 2011, she became Associate Professor in Hanoi Medical University. She is the Deputy Director of Institute for Preventive Medicine and Public Health, Hanoi Medical University. She has published more than 50 papers in reputed journals.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 131 Philippe Boucher, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Wnt5a protects against intracellular cholesterol accumulation through inhibition of the mevalonate pathway Philippe Boucher University of Strasbourg, France

dipose tissue is an easily accessible tissue that in addition to its roles in storage of excess energy in form of triglyceride also Acontains the largest pool of cholesterol in the body and plays a critical role in maintaining cholesterol homeostasis. The mechanism of this regulation is however unknown. We reported previously that LRP1, a trans-membrane receptor positively regulates a Wnt5a signaling pathway that protects against intracellular cholesterol and cholesteryl-esters accumulation in cells submitted to adipogenesis. To investigate the role of Wnt5a in cholesterol homeostasis we generated mice overexpressing Wnt5a in adipose tissue (aTgWnt5a). aTgWnt5a mice fed a regular chow diet exhibit a decrease in adipocyte cholesterol levels with no difference in triglycerides content compared to controls. This was accompanied by an inhibition in adipose tissue of the HMG- CoA reductase, the rate-limiting enzyme for cholesterol biosynthesis. mRNA and protein levels of HMG CoA reductase were both severely decreased compared to controls suggesting that Wnt5a interfere with cholesterol biosynthesis. In agreement with this hypothesis, we found an increase in Insig-1 protein and mRNA levels in adipocytes from these mice, with no difference in SREBPs mRNA expressions. We confirmed in vitro the effects of Wnt5a on the HMGCoA reductase levels. Similarly, Wnt5a increased Insig-1 protein when stably transfected in MEFs. In agreement with an inhibition effect of Wnt5a on cholesterol biosynthesis, SREBP2 cleavage, and nuclear translocation were reduced in Wnt5a transfected cells. These data suggested that Wnt5a protects against cholesterol intracellular accumulation through inhibition of its biosynthesis.

Biography Philippe Boucher is professor of Physiology at University of Strasbourg. After a Ph.D. at the University of Lyon, France and a postdoctoral fellowship at UT Southwestern Medical Center at Dallas he became an Assistant Professor of Physiology at University of Strasbourg before moving on a Full Professor position. His lab aims to understand cell-signalling networks and, in more specific terms, how LRP1 and its partners impact on growth- promoting and differentiation signals that protect against disorders such as atherosclerosis and obesity. He has published more than 25 papers in reputed journals. His work has identified several fundamental molecular mechanisms by which these genes protect against atherosclerosis, heart failure, and maintain cholesterol homeostasis.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 132 Lydia Kaduka et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Obesity and the associated cormobidities among urban residents of Karen/Langata and Kibra Constituencies in Nairobi, Kenya Lydia Kaduka1, Yeri Kombe1, Zipporah Bukania1 and John K. Bore2 1Kenya Medical Research Institute, Kenya 2Kenya National Bureau of Statistics, Kenya

Background: Obesity is known to impact negatively the functioning of the cardiovascular system. According to the Kenya Ministry of Health Report (2012), up to 13.3% of males and 24% females are overweight and obese while 46.2% males and 42.7% females have high blood pressure. The aim of this study was to determine the prevalence of obesity and the associated factors among urban residents of Karen/Langata and Kibra Constituencies in Nairobi, Kenya. Methods: This was a cross-sectional study based on a three-stage cluster sampling methodology across the socio-economic strata. Assessments included measurement of weight and height, blood pressure (BP) check, fasting blood glucose, the lipid profile and C-reactive protein concentrations. Information on demographics was also collected using a structured questionnaire. Data was weighted and analyzed with values of p<0.05 considered statistically significant. Results: A total of 537 adults (m: 50.3%; w: 49.7%) aged 18 years and above participated in the study. The mean age was 38.09±13.4 years. The prevalence of obesity was 16.3% and higher in women than men (w: 27.3% vs. m: 5.9%). A significant positive association (p<0.001) was observed between BMI and increasing age in both sexes. In men, obesity was significantly associated with the lipid profile (p<0.001), higher socio-economic status (p<0.001), BP (p=0.004) and fasting blood glucose concentration (p=0.003), whereas in women, BMI was strongly associated with CRP (p=0.002), the lipid profile (p<0.05) and BP (p=0.001). Conclusions: The gender disparity observed in the presentation of obesity and concomitant cormobidities calls for health promotion and intervention efforts geared not only towards the observed cardiovascular risk factors but also the social cultural and economic factors that may be responsible for the observed findings.

Biography Lydia Kaduka holds a Ph.D. in Medical Biochemistry from Kenyatta University (Kenya) and a Masters in Clinical Biochemistry and Molecular Biology from University of Surrey (UK). She works as a senior research officer at Centre for Public Health Research in Kenya Medical Research Institute (KEMRI). Her research interests are in cardiovascular disease, nutrition and public health. She has published in many reputed journals. She currently serves on the KEMRI/National NCD Programme.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 133 Moise Bendayan et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Gastric leptin- An exocrine secretion regulating food intake Moise Bendayan and Philippe Cammisotto University of Montreal, Canada

eptin plays important roles on the nutritional and energy status of the organism. It is secreted in an endocrine way by the Ladipose tissue and in an exocrine way by the gastric mucosa. Gastric epithelial chief cells express and secrete leptin into the gastric lumen through their RER-Golgi-secretory granules regulated pathway together with classical gastric enzymes such as lipase and pepsinogen. Upon food intake, the content of the granules is released into the gastric lumen. Leptin resists the drastic proteolytic conditions of the gastric juice thanks to its binding to the soluble isoform of the leptin receptor. The formation of the leptin-leptin receptor complex takes place in the secretory granule prior release. Once secreted, this complex crosses the pyloric sphincter reaching the duodenal lumen. Transmembrane leptin receptors lining the intestinal cells apical microvilli bind the luminal leptin and internalize it through clathrin-coated vesicles. Leptin regulates absorption of nutrients and participates in the intestinal mucosa integrity. However some of the internalized leptin is transported through transcytosis to the baso-lateral membrane to be released into the interstitial space to reach the blood circulation and the hypothalamic target cells. Since leptin is normally present in the gastric lumen and reaches the circulation through transcytosis across the intestinal cells, we designed an oral formulation of leptin that by using the same pathway can reach the blood circulation. Such an oral formulation of leptin is able to control food intake by various normal animal models and restores leptin levels in animal models expressing leptin deficiency.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 134 Rick Weiss, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

VioScreen: A web-based self-administered dietary habits questionnaire that provides an efficient and thorough assessment of critical dietary information about a patient or research subject Rick Weiss Viocare Inc., USA

ost primary healthcare practitioners recognize the important relationship among nutrition and health. Few incorporate Mdietary counseling into routine practice. The facilitation of lifestyle behavior modification during primary care visits is limited due to the lack of time and expertise. Technological advances can facilitate assessment of dietary intakes as well as behavioral tracking to produce improved health outcomes. VioScreen, an innovative web-based food frequency questionnaire that uses complex branching technology and 1,200 food portion images, enables healthcare professionals to quickly and accurately assess a patient’s diet. Results, which are immediately available, include a food pattern analysis and a list of foods and nutrients consumed, and the “top foods” that contribute the most to key nutrients, i.e. top saturated fat foods. The use of this technology facilitates the dietary intakes assessment allowing more time to spend on individualized counseling than on capturing dietary intake. VioScreen was evaluated and determined very accurate through a study with 74 subjects conducted at The Ohio State University. VioScreen correlations were substantially higher than reported for many other paper FFQs used in major studies, being at or above 0.80 for most macronutrients (0.90 alcohol, 0.84 saturated fat, 0.82 fat, 0.79 carbohydrate) and 0.67 for protein. All subjects rated VioScreen as easy to use and 99% would complete the questionnaire if asked by a doctor. VioScreen enables the delivery of individually tailored diet counseling in the context of standard primary care. The presentation will discuss the technology and successful clinical implementation examples.

Biography Rick Weiss is the President of Viocare, Inc., which he founded 20 years ago. Viocare develops innovative and scientifically-validated dietary and physical activity assessment and behavioral change systems for researchers, clinicians, and wellness counselors. Mr. Weiss has been the Principal Investigator on 21 National Institutes of Health grants and contracts, valued at over $10 million. These projects have formed the basis of Viocare’s product line including a wellness program for counselors, VioWell and an electronic dietary history questionnaire, VioScreen. Viocare’s systems have been used by major research and clinical organizations such as Mayo Clinic, Brigham and Women’s Hospital, Eli Lilly, FDA, USDA, and NIH. Under a current NIH award, he is developing a mobile food intake app that uses image recognition to automatically identify the food and portion size to generate an accurate but low burden method for dietary intake assessment. He has presented at major healthcare conferences (Obesity Society, ICDAM, ISBNPA, mHealth) and published in peer review journals about new techniques for dietary assessments. He started his career as an Applied Researcher at Bell Laboratories after receiving a Bachelor’s degree in Electrical Engineering and Math with honors from Carnegie Mellon University and a Master’s degree in Electrical Engineering and Computer Science from Princeton University.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 135 Samuel Stein, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Using cognitive behaviour therapy to lose weight and lower cholesterol Samuel Stein CAMHS Academic Unit and University of Bedfordshire, UK

ognitive therapy is based on a model which explains how thoughts and feelings relate to each other.The synchronous Crelationship between cognitions, behaviour and mood suggests that a change in any one component is likely to produce changes in the other. Beck's model of cognitive therapy emphasise the underlying cognitions or beliefs in an individual's overt difficulties. Cognitive therapy is therefore a treatment aimed at understanding primarily cognitive structures in an individual's problem, and devising intervention strategies aimed at changing, but initially challenging underlying irrational beliefs. Through modelling by the therapist, education and challenging verbal techniques, aimed at helping the patient to think about his problem and make the various links between symptoms and vulnerability factors, cognitive therapy guides the patient to a greater understanding of his problems.The model states that in the presence of emotional disturbance there will be: Negative automatic thoughts, patterns of regularly occurring errors and core beliefs and dysfunctional assumptions. In England, most people are overweight or obese. This includes 61.3% of adults and 30% of children. They have a higher risk of getting diabetes, heart disease and cancer. Excess weight can also make it more difficult for people to find and keep work, and it can affect self-esteem and mental health. Health problems associated with being overweight or obese cost the NHS more than £5 billion every year. Obesity is everybody’s business and it is the responsibility of individuals to change their behaviour to lose weight. Both motivation and a positive attitude are needed. As described by dieticians, people also need to change the way that they eat, replace unhealthy foods, say no to extra portions and make conscious choices. Individuals have to be willing to change how they live and be open to new ways of doing things, having daily routines, setting new rules and being more active. This paper therefore explores how cognitive behaviour therapy principles and techniques can be used to help overweight or obese individuals who need to lose weight or lower their cholesterol.

Biography Samuel Stein is an Attending Child, Adolescent and Family . He graduated from the University of the Witwatersrand Medical School in 1986, and undertook his psychiatry training in Oxford, Cambridge and at St. Mary's Hospital in London. He is a Fellow of the Royal College of Psychiatrists and has edited several books including: Disorganized Children. He is also a Visiting Professor at the Institute for Health Research at the University of Bedfordshire and the Post-Graduate Medical Institute at Anglia Ruskin University. He has a commitment to service-oriented research and many of his initiatives have been implemented nationally as examples of accessible and effective good practice.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 136 Jani Takatalo, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

The association of disc degeneration with obesity Jani Takatalo University of Jyvaskyla, Finland

ow back pain (LBP) is a most debilitating condition. LBP can lead to decreased physical function, compromised quality of life, Land psychological distress. Obesity has been recently recognized as a risk factor of LBP. Lumbar intervertebral disc degeneration has been associated with LBP especially in younger population and recently the association of lumbar disc degeneration with obesity has also been published in few studies, again in younger population. The prevalence of disc degeneration increases with age and is therefore more challenging to find associations with confounding factors. There are several mechanisms through which obesity can impact the lumbar intervertebral discs. One of the oldest explanation and still competent is mechanical loading caused by extra weight on lumbar discs. Extra loading on the lumbar intervertebral discs may compromise disc nutrition and cause degradation of the extracellular matrix of the lumbar disc and, thus, causing disc degeneration. could reasonably cause this extra load on disc and therefore obese males are in greater risk for disc degeneration. High body mass index, high waist circumference and abdominal obesity measured in magnetic resonance imaging are associated with lumbar disc degeneration among young males. Obese people are also usually less physically active and sit more during the day, which can compromise the blood supply and nutrition of the disc, which are even in optimal conditions the least vascularized tissue in the body. This may cause increase of pH and cell death in the disc. Obesity is a risk factor for cardiovascular disorders and through dyslipidemia can cause atherosclerosis. Atherosclerosis by itself is a risk factor for lumbar disc degeneration because the blood and nutrient supply into the disc is diminished. Recently the obesity has been found to be a low-grade systemic inflammation condition in which adipocytokines stimulate hepatocytes to produce C-reactive protein. C-reactive protein can cause endothelial dysfunction and subsequently atherosclerosis. From another perspective, low back pain, which may be caused by disc degeneration but many other reasons as well, can be so debilitating condition physically and mentally, that it may lead to obesity.

Biography Jani Takatalo graduated as Physical Therapist in 2002 from Rovaniemi University of Applied Sciences (Finland) and Master of Health Sciences () at University of Jyväskylä (Finland) in 2006. He has been working as a part time Physical Therapist since graduating and graduated as M.D. in spring 2012. Nowadays he is working as a doctor for patients with musculoskeletal disorders and he is specializing for Physical Medicine and Rehabilitation. He will complete his Ph.D. (Medicine) on disc degeneration by the end of 2013.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 137 Crystal Petrello, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Non-profit organization offers 16-week weight loss program to reduce prevalence of obesity in Las Vegan’ adults Crystal Petrello REinVIGORate, USA

EinVIGORate is a non-government/non-profit organization (NGO) whose mission is to inspire and educate at-risk, low Rincome adults for weight loss and wellness in the Las Vegas community in order to promote a trickle-down effect of wellness, activity, and nutritious eating in the home. The program, which is free of charge for participants, targets obese adults (BMI of ≥30) who have the time and commitment to participate in a sixteen-week program and who would normally not have the funds to hire a personal trainer, dietitian, and mental health professional. Our focus is to change the healthy eating and physical activity behavior of the adults that will allow the children in the homes to see the adults as the health role models. The program, in its third round, has now grown to over twenty participants. We have had three groups participate in the REinVIGORate program. The first group of five individuals had three successfully complete programs with marked results. The second group of five individual had two successfully complete programs with remarkable results. The most recent group, currently in week 4 of 16, has started off strong. Our greatest challenge is helping our clients work on changing their emotional or stress related behavior issues attached to eating, over-eating, and portion control. This year marks the first year that the focus is equally divided among the various areas the wellness continuum including psychosocial/mental health, physical health, and nutrition.

Biography Crystal Petrello M.S., RDN, LD is a registered dietitian and completed her Master’s in Community Nutrition with her research in Food Security. Her research was on the fruit and vegetable intake and behaviors of low income households in the Appalachian Mountain Region of the United States. She is the co-founder and Director of Nutrition for REinVIGORate, a primer non-profit weight loss program based in Las Vegas, Nevada. She is also a podcaster for her company PartyRight Life and writes for multiple formats including her book “But I’m Hungry!” which she co-authored and was released in 2012.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 138 Suleiman Al-Sabah et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Incretin response to a standard test meal in a rat model of sleeve gastrectomy with diet˗induced obesity Suleiman Al-Sabah, Fahad Alasfar, Ghanim M Al-Khaledi, Reshma Dinesh, Mervat Al-Saleh and Habib Abul Kuwait University, Kuwait

Introduction: Currently the most effective treatment for obesity is bariatric surgery. Surgery that includes gastro-duodenal bypass not only produces sustained weight loss but also improves glycemic control and insulin sensitivity. Previous studies have shown that sleeve gastrectomy (SG) produces similar results and implicate the incretin hormones. Methods: Male Sprague Dawley rats were divided into four groups; lean control (Lean), diet-induced obese (DIO), DIO animals that had undergone SG and DIO animals that had been sham-operated (Sham). After a 2 week recovery period, an oral glucose tolerance test (OGTT) was performed and the incretin response to a standard test meal measured. Blood sampling was performed in free moving rats at various time points through chronic vascular access to the right jugular vein. Results: There was a significant increase in the bodyweight of animals fed with a high-fat, high-sugar diet compared to lean which was reversed by SG. DIO caused in an impairment of the GLP-1 but not GIP response to a standard test meal. SG resulted in a dramatic increase in the GLP-1 response to a standard test meal but had no effect on the GIP response. A rapid rise in blood sugar was observed in the SG group following a standard test meal that was followed by reactive hypoglycemia. Conclusions: SG dramatically increases the GLP-1 response to standard test meal, this may contribute to the resolution of diabetes observed in human subjects who undergone SG.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 139 Fornes Miguel Walter et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Olive oil prevents sperm changes promoted by hipercholesterolemic diets Fornes Miguel Walter and Saez Tania Estefania National University of Cuyo & National Research Council (CONICET), Argentina

emen and sperm cell from hypercholesterolemic rabbits (HCR) exhibit several abnormalities such as teratospermiae, decrease Sin sperm number, reduced resistance to the hyposmotic shock and spermatic dysfunction accompanying high serum cholesterol levels and increased arterial pressure. HCR acquired these changes due to a fat diet; specifically the balanced diet for rabbit supplemented which commercial grease from cow (approximately, 0.5% cholesterol v/v). The malformed sperm consist in a sperm head folding in the longitudinal axes, permanent cytoplasmic droplet, and/or acrosomal swollen. Functional changes correspond to both reduced protein tyrosine phosphorylation during sperm capacitation and percentage of acrosomal reacted sperm under progesterone stimulation. These changes were reversed by addition of olive oil to the grease diet. We investigated key molecules involved in cholesterol metabolism, and found changes in the expression of mRNA and protein oftranscription proteins SREBP 1 y 2 under different diets. Clearly our results show that olive oil added to fat diet reverses the deleterious effect of such types of diet over reproductive parameters and for the first time molecular actions of olive oil on cholesterol metabolism is reported.

Biography Fornes Miguel Walter has completed his degree (M.D.) and Ph.D. from the School of Medicine at the National University of Cuyo (FCM, UNCuyo). Now is the chairman of the Histology and Embryology Area from the FCM, UNCuyo and Director of basic courses at the Aconcagua University and member of the research carrier at national research council (CONICET). He has published more than 50 papers in reputed journals devoted to the biology of reproduction and serving as an editorial board and reviewer member of prestigious journals.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 140 Giacomo Balbinotto Neto et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Economics determinants of physical activity participation in Brazil Giacomo Balbinotto Neto2, Marcia Regina Godoy1, Angelica Massuquetti1, Andre Filipe Zago de Azevedo1 and DivanildoTriches1 1Universidade do Vale do Rio dos Sinos, Brazil 2Universidade Federal do Rio Grande do Sul, Brazil

Background: Poor diet and a lack of physical activity are major factors to the worldwide obesity epidemic, and make a significant contribution to the overall burden of disease. More than 50% of Brazilian population is obese or overweight and sedentary. The determinants of individual participation in physical activity are not well understood. Objectives: This paper uses a time allocation framework to explore how economic and demographic factors influence participation in physical activity of women between 20 and 40 years, the South and Northeast regions of Brazil. To estimate the determinants of participation in physical activity or sport of women between 20 and 40 years, the South and Northeast regions of Brazil. Methods: The analysis examines frequency of participation in physical activity using a probit model. We used data from the Brazilian Household Survey (Pesquisa Nacional de Amostra de Domicilios) of 2008, with survey 391.000 observations for men and women in Brazil. Our sample size is 21.971 observations for women between 20 and 40 years old. The explanatory variables included in analysis of determinants that influences the likelihood of participating in physical activity are used: The total time spending in working, non-market work (home works) and commute time to work. Individual characteristics such as age, education, income, marital status, and the presence of dependent children under 5 years-old, self-perceived health status, tobacco use, and health insurance. Results: On average, 28% of women interviewed practiced some physical activity, but as there is a positive relationship between income and practice of physical exercise, the percentage of practitioners varies from 11% to 72% depending on the household per capita income and schooling. In the South the non-white women are more sedentary. For the duration of the practice of physical exercise, 91% of practitioners spent at least 30 minutes of physical activity. In all Brazilian regions, the walking/running is the sport modality more frequent. But there are an inverse relation between walking/running and schooling and income. The women with lower schooling and lower individual and family income do less likelihood of participation in physical activity. Furthermore, the sedentary women also invest less in health-promoting activities and smoke more. The disastrous consequences of the risky behavior of sedentary reflected on worst self-perceived health status. Women in better health are more likely to participate in more frequent physical activity. Women with dependent children under five years-olds tend to participate in lower weekly levels of physical activity. The women with high education level, despite have more time total occupied, does more physical activity. Our results from logit regressions showed that the main factors that affect the physical activity participation are schooling, income and to have children under five. The impact of schooling and income is positive. Findings: The results confirm the health capital theory showing that women with more years of education invest more in health by doing physical activity and buying more health insurance than the sedentary women. The presence of children reduces the probability of participation, so successful policy interventions should be linked to daycare in some way.In terms of policy; the results suggest that policy makers should focus on the promotion of familyfriendly exercise programs and facilities especially for working women. The preference for walking/running suggest that policies which make exercise more convenient, and hence decreasethe opportunity cost of exercise, will help to encourage more people to participate in physical activity.

Biography Giacomo Balbinotto Neto has completed his Ph.D. from USP University. He is the Professor at Universidade Federal do Rio Grande do Sul, Faculty of Economics, Porto Alegre, Brazil. He has published more than 150 papers in reputed journals and has been serving as an editorial board member.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 141 Samia A. Khatwa et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

A study of obesity among females attending a hospital-based infertility clinic in Alexandria, Egypt 2011 Samia A. Khatwa, El Deeb D, Moemen M, Gewaifel G and Elkassar Y Alexandria University, Egypt

Introduction: The prevalence of obesity has increased globally at an alarming rate over the past two decades. Egypt ranks the first in obesity among the African countries and 14th in the world, according to a recent WHO statistics. This study is aimed at comparing obesity prevalence in the sample to that of population, associating obesity metrics with gynecological profile parameters and response to infertility management. It is also aimed at recommending a simpler substitute for screening obesity than body mass index to be used in primary health care settings. Subjects and Methods: The study sample totaled 219 females who were assessed for obesity metrics. Patients were interviewed as regard gynecological profile parameters. Subjects’ files were reviewed for available investigations’ results. After a follow up period of nine month; outcome of infertility management was verified. Roc curve was drawn for different body circumferences taking body mass index (BMI) as the golden test. Results: The prevalence of obesity was higher in the sample .Obesity was associated with various studied parameters like age of menarche, length and regularity of menstrual cycle and type of infertility. Outcome of infertility management was unfavorably associated with obesity, android fat distribution and history of weight changes. Compared to BMI, hip circumference was the most accurate substitute. Conclusion: Obesity is a highly prevalent problem that needs to be tackled in infertility clinics to increase success rates of management. When there are constraints to calculate BMI in primary health care facilities, hip circumference is the recommended substitute.

Biography Samia A. Khatwa has completed her M.D. at the age of 33 years from Faculty of Medicine, Alexandria University, Egypt. The subject of dissertation was: Inpatients feeding service in hospitals of Alexandria. She is a Professor of Public Health at Alexandria Faculty of Medicine. She has published more than 20 papers in reputed journals and supervised a large number of master and doctoral theses. The areas of interest in her research are: nutrition, behavioral sciences and .

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 142 Semeeh A. Omoleke et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Socio-demographic correlates of overweight and obesity in Nigerian adults Semeeh A. Omoleke1, Adetoyeje Y. Oyeyemi2, Salamatu A. Umar2 and Adewale L. Oyeyemi2 1World Health Organisation, Nigeria 2University of Maiduguri, Nigeria

Background: Baseline information on socio-demographic correlates of body weight status is relevant for controlling the epidemic of chronic non-communicable diseases (NCDs) now occurring in many African countries. However, comparable data (between developed and developing countries) in this context are extremely scarce in Nigeria. This study assessed the socio-demographic correlates of overweight/obesity in Nigerian adults, with a view to informing prevention and control interventions. Methods: A cross-sectional survey was conducted among a representative sample of 1411 Nigerian adults (age: 20-65 years and 43.1% female) in metropolitan Maiduguri, Nigeria. Anthropometric measurements of height and weight and interview-led self-reported socio-demographic information were conducted. The primary outcome was overweight/obesity (body mass index [BMI]≥25 kg/m2) vs. normal weight (BMI=18.5-24.9 kg/m2). Socio-demographic correlates of overweight/obesity were identified using the binary logistic regression. Results: Overall, 33.9% of Nigerian adults were overweight/obese (24.3% with BMI >25 kg/m2; 9.5% with BMI >30 kg/m2). There was no significant difference (p>0.05) in the prevalence of overweight/obesity between men (33.3%) and women (34.7%), but overweight/obesity tends to increase with increasing age category (p<0.001). After adjustment for sufficient physical activity, overweight/obesity was positively associated with female gender (OR=1.44, CI=1.05-1.99), being single or not married (OR=2.78, CI=1.33- 5.82), being employed by the government (OR=1.86, CI=1.30-2.66) and belonging to the Kanuri or Shuwa ethnic group (OR=1.83, CI=1.28-2.64), but negatively associated with lower income (OR=0.51, CI=0.32-0.88) and belonging to the Igbo ethnic group (OR=0.33, CI=0.19-0.54). Conclusions: Socio-demographic factors were associated with being overweight/obese among Nigerian adults. These findings suggest that socio-demographic specific interventions may be warranted in the control and prevention of overweight or obesity in Nigerian adults.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 143 Shuji Inoue, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Pathogenesis and pathophysiology of ventromedial hypothalamic (VMH) lesion-induced obese rats-comparison with other hypothalamic induced obese rats Shuji Inoue Kiryu University, Japan

e have been investigating the pathogenesis and pathophysiology of ventromedial hypothalamic (VMH) lesion-induced Wobese animals, a representative model of hypothalamic obesity, for 40 years and recently, we discovered a new type of hypothalamic obesity induced by bilateral destructions of the area between bilateral VMHs which is corresponding to the area between arcuate nuclei (ARN) and paraventricular nuclei (PVN) in the hypothalamus (referred to as Between-VMHs; B-VMHs) in rats. The talk deals with comparison of pathogenesis and pathophysiology between VMH lesions-induced hypothalamic obesity and other hypothalamic lesion-induced obesity including B-VMHs lesions-induced obesity. VMH lesioned rats show more hyperphagia and more obesity, and higher levels of serum insulin and leptin than B-VMHs lesioned rats. Disconnection of α-MSH pathway by determined histochemical neural fiber staining in ARC-PVH axis for food intake regulatory system contributes to hyperphagia and obesity in B-VMHs lesioned rats, but the origin of hyperphagia in VMH lesioned rats is more complex. Basal and postabsorptive hyperinsulinemia induced by autonomic derangement (vagal hyperactivity with sympathetic hypoactivity) is the primary cause of VMH lesions-induced obesity. On the other hand, in other hypothalamic obesity (destruction of PVM, ARC, Between VMH, and LH) including B-VMHs lesion-induced obesity, hyperphagia with postabsorptive hyperinsulinemia is the primary cause of obesity. Cell proliferation in visceral organs (stomach, small intestine, liver and pancreas) by histochemical stainings and electron microscopic examinations are observed in VMH lesioned rats, which is due to vagal hyperactivity in autonomic derangements by VMH lesions, in contrast, no cell proliferation in the visceral organs are observed in B-VMHs lesioned rats due to a lack of autonomic derangements, similar no cell proliferation may appear in other hypothalamic lesioned rats in a similar mechanism. More recently, we have discovered that adiponectin production and release are increased, which lead to elevated serum adiponectin in VMH lesions-induced obese animals inspite of enlarged adipocytes and increased body fat also due to vegal hyperactivity.

Biography Shuji Inoue has completed his M.D. at the age of 26 years old and got Ph.D. from University of Tokyo, School of Medicine. He has been working for investigating the pathogenesis and pathophysiology of hypothalamic obesity for 40years. He is the vice-president and dean of Faculty of Health Care, Kiryu University, Japan. He has published more than 200 English papers in reputed journals and is now serving as Editor-in-Chief of Obesity Research & Clinical Practice.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 144 Derouiche Abdelfettah, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

The double burden of malnutrition in Casablanca, Morocco Derouiche Abdelfettah Universite Hassan II Mohammedia Casablanca, Morocco

he epidemiological situation in developing countries is rapidly switching to a model where obesity and associated diseases are Tbecoming a major public health concern. Countries in Northern Africa, including Morocco, are characterized by moderate levels of overweight and obesity, moderate levels of under-nutrition in specific population and age groups, and widespread micronutrient deficiencies. To assess the amplitude of the double burden of malnutrition in Moroccan households we conducted a survey in 6 neighborhoods of Casablanca, Morocco. 426 adult women and 240 preschoolers were randomly selected using a cluster sampling. Anthropometric parameters were measured according to the guidelines of the World Health Organization (WHO). Obesity in adults was determined using the body mass index cutoffs from the WHO. Underweight, stunt and obesity in children were determined using the WHO child growth standards. Results showed 47% obesity and 36% overweight among women, while 19% children were underweight and 15% were stunted, we also noticed 8% obesity among children. These data allowed us to have an idea about the amplitude of the double burden of malnutrition in low and middle income households from Casablanca; The fact that we found it in a considerable part of the population is an indicator of other possible aspects of malnutrition. It is becoming imperative to conduct a thorough study on the food behavior in these households to understand the complexity of this phenomenon.

Biography Derouiche Abdelfettah was born in 1957 in Meknes Morocco and holds a Ph.D. from the University of Nancy I France, Nutrition Bio-industries and a Doctor of the University Hassan II, Casablanca Morocco in Human Nutrition. Currently is Professor and researcher in Human Nutrition Faculty of Sciences Ben Sik Casablanca and Head of Research Group: Human Nutrition and holds about twenty publications in the field of protection cardiovasculaire with argan and olive oils and that of malnutrition.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 145 Abhijeet Ghosh, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

General practice; best placed to curb Australia’s obesity epidemic Abhijeet Ghosh University of Wollongong and Illawarra-Shoalhaven Medicare Local, Australia

hile national policies and state wide approaches to preventive health and health promotion is definitely required to Waddress the issue of chronic disease globally; local and smaller catchment surveillance systems are the need of the hour to continuously implement focused strategies targeting these conditions at small community levels and thereby actively evaluating local health strategies so as to regularly monitor the trends of chronic disease across nations such as Australia. On these lines the Illawarra-Shoalhaven Medicare Local which is one of the 61 medicare locals formed under the Australian government National Health Reform Agreement, undertook a pilot study to assess the feasibility of implementing a sentinel site surveillance system in regional NSW to monitor chronic disease prevalence and its associated risk factors. The study was conducted in one of the major general practices in the Illawarra-Shoalhaven catchment of regional NSW and found higher than national average estimates were found for the age-adjusted prevalence of obesity/overweight (67.1 vs. 63.4%). These findings were higher than prevalence estimates of obesity identified in the regional health profile of the Illawarra-Shoalhaven region which estimated an obesity prevalence of 57.2%. While the pilot study has demonstrated that routinely collected general practice data offers a feasible opportunity for monitoring obesity prevalence and its associated risk factors; further research is being undertaken to include larger number of sentinel sites that are generalizable to the population being served to provide an accurate and region-specific system for the purposes of planning evidence based and consumer specific interventions to control the burgeoning epidemic of obesity in regional Australia.

Biography Abhijeet Ghosh has a Bachelor of Medicine & Bachelor of Surgery (MBBS) from University of Delhi, India and post graduate qualifications in Medical Ultrasonography. Furthermore, he completed his Master of Science in Population Health in 2010 and has been working in the field of Public Health research and health management since 2007. He is currently the manager of Population Health and Planning at the Illawarra-Shoalhaven Medicare Local, a not-for-profit health organisation in NSW Australia. Additionally he has also been teaching Epidemiology at the University of Wollongong since 2011.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 146 Ana Vujaklija Brajkovic, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Hyperglycemia in critical illness - Risk factor for later development of glucose metabolism abnormalities Ana Vujaklija Brajkovic Zagreb University Hospital Center, Croatia

Introduction: Critical illness is commonly complicated by hyperglycemia caused by mediators of stress and inflammation. Severity of disease is the main risk factor for development of hyperglycemia, but not all severely ill develop hyperglycemia and some do even in mild disease. We hypothesized that acute disease exposes a latent disturbance of glucose metabolism which normalizes after discharge but puts those patients at higher risk for developing pre-diabetes and type 2 diabetes. Patients and Methods: Patients admitted to the intensive care unit of the University Hospital Centre, Zagreb, due to acute coronary syndrome (ACS), sepsis, pulmonary embolism, pulmonary oedema and respiratory insufficiency were included in the research. Patients with no history of impaired glucose metabolism were divided into hyperglycemia group (glucose ≥7.8 mmol/l, measured on at least two occasions) and normoglycemia group. Glycated hemoglobin, fasting glucose on the day of discharge and oral glucose tolerance test within six weeks after discharge were all performed in order to disclose patients with unknown diabetes or pre-diabetes who were excluded from the research. Results: Hyperglycemia was present in 30.6% of all patients. It was more frequent in patients with sepsis and other diagnoses (pulmonary embolism, pulmonary oedema, respiratory insufficiency) (43%) than with ACS (20.2%). Glucose concentration was 10.2 (8.9-13) mmol/l in the hyperglycemia and 5.7 (5-6.4) mmol/l in the normoglycemia group. Patients with hyperglycemia were older, had higher body mass index and were more severely ill (higher APACHE II, SAPS II, SOFA score) than patients in the normoglycemia group. Follow-up was done on 70 patients with hyperglycemia, of which 10 (14.2%) developed impaired fasting glucose/ impaired glucose tolerance (IFG/IGT) and 30 (42.9%) diabetes. 186 patients in the normoglycemia group completed the follow up, of which 10 (5.4%) developed IFG/IGT, and 21 (11.3%) diabetes. Relative risk for developing IFG/IGT was 4.13 (95% CI 1.84-9.24), and diabetes 4.19 (95% CI 2.61-6.73). Conclusion: Patients with hyperglycemia during critical illness who were not diagnosed with diabetes before or during the hospitalization should be considered a population at increased risk for developing pre-diabetes and diabetes.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 147 165th OMICS Group Conference

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Accepted Abstracts (Poster)

Obesity-2013 Page 149 Kepher H. Makambi et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Relationship between socio-demographic factors and obesity through lifestyle factors in African American women: A path analysis approach Kepher H. Makambi, Sherrie L. Wallington, and Lucile L. Adams-Campbell Georgetown University Medical Center, USA

Background: Socio-demographic, lifestyle factors and physical activity are important in the understanding of obesity. The possibly direct or indirect nature of the associations among these factors and the eventual link to obesity is not well understood. We assess the indirect association between socio-demographic and obesity through lifestyle factors. Methods: A case-control study involving African American women conducted at Howard University Cancer Center. One hundred ninety eight participants gave information on anthropometric measurements, socio-demographic factors (age, marital status, income and education) and lifestyle factors. Path analysis was utilized to assess associations between socio-demographic factors and obesity through physical activity, smoking or alcohol consumption. Results: The mean age of the participants was 55±12 years, with 50% being obese (BMI≥30 kg/m2). Obesity level decreased by approximately 17% for every one year level increase in education via its prior effect on vigorous physical activity. Age had a significant positive indirect effect on obesity through vigorous physical activity with obesity levels increasing by approximately 7% for every one year increase in age. Conclusions: Vigorous physical activity mediates the association between education and obesity as well as age and obesity.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 150 Buccheri Teresa, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

The importance of psychodiagnostic evaluation to structure effective and integrated prevention program: A preliminary Sicilian study Buccheri Teresa University of Messina, Italy

hildhood obesity is an increasingly common that has already reached alarming levels in children and adolescents. CThe phenomenon is worrying because childhood obesity is a predictor of obesity during adulthood and it has also been associated with physical and psychological problems (Quattropani, MC. & Buccheri, T. 2013, in press). It has been shown that childhood obesity has a multifactorial aethiopathogenesis (AAP. 2003) because of genetic, biological, neurological, neuroendocrine, psychological, environmental and socio-cultural factors which play an important role in increasing weight and hunger and in developing unhealthy behaviors and habits. Psychodiagnostic evaluation represents the first step to structure a prevention program following a multidisciplinary and integrated perspective. The present work is a preliminary study that aims to evaluate obese children in different perspectives, individual, relational, medical, and psychological. The study involved 32 families with overweight/obese children; questionnaires were administered to the parents: Socio- demographic questionnarie, questionnaire about eating and physical habits, family nutrition and physical activity interview, eating disorder inventory II (Rizzardi et al. 1995), parenting styles dimensions questionnaire (Confalonieri et al. 2009), questionnaire about eating and physical habits of children and QUIT (Italian Questionnaire for Temperament). Questionnaires were administered to the sample however only 15 families completed evaluation; fathers of other families didn’t answer the questions for different reasons (lack of will, contrasts with wife, and lack of time). FNPA screening tool evaluated familial environment and habits, only 15.6% of the sample gave a low FNPA total score showing unhealthy lifestyles and habits. Other data are still in progress.

Biography Buccheri Teresa is completing her Ph.D. at the age of 30 years from University of Messina, after graduation at “La Sapienza” University of Rome. She is psychologist, psychotherapist, expert in familial psychotherapy and eating disorders. She is an expert witness for the court. Since she has become psychotherapist, she is working with individual and familial in private practice.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 151 Caglar UNLU et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

The methods and goals of combat obesity for armed forces Caglar UNLU, Unal DEMIRTAS and Mehmet Cetin Gulhane Military Medical Academy, Turkey

besity is one of the diseases that affects individuals and societies which is increasing rapidly in the world. For this reason, Opolicies are being developed all over the world; action plans are prepared about combat obesity. The reason of obesity is multifactorial so combat obesity involves a multidisciplinary approach. Nowadays, intuitional combat has gained importance as well as individual. Armed forces should also be included as an institution to this combat obesity. The aim of armed forces is to have well-trained staffs who are always ready for battle; have superior physical and moral strength, knowledge and skills required by the age. Soldiers always have to be fit for difficult terrain conditions and one of their enemies is obesity. Obesity, both itself and the secondary diseases (heart-vein diseases, diabetes, etc.), cause loss at fighting manpower. For this reason, combat obesity is very important for the armed forces. In this context, institutional request and insistence should be provided and implemented from team to upper stages, financial arrangements should be made, current situations should be determined and researches should be supported at armed forces. Within the scope of the prevention of obesity, military personnel should be informed and awarded about obesity, adequate and balanced nutrition, regular physical activity and habits should be gained at barracks and supported by commanders, physical activity opportunities should be increased and environmental factors should be improved.

Biography Caglar UNLU has completed his M.D. at the age of 24 years from Gulhane Military Medical Faculty. He had worked as a practitioner for ten years. He has been officially registered as a M.D. student in the M.D. program of the Department of Military Health Services, Gulhane Military Medical Academy.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 152 Hyacinthe T. Kankeu, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Prevalence of obesity and overweight among Cameroonian women, 2004-2011 Hyacinthe T. Kankeu Aix-Marseille School of Economics, France

on-communicable diseases (NCDs) now account for a very large burden in terms of both mortality and morbidity in Nlow- and middle-income countries (LMICs). Although obesity is a major health risk for many NCDs such as diabetes, hypertension, coronary heart disease, and some forms of cancer, little is known about its magnitude in Cameroon. The objective is to study the trends of the prevalence of obesity and overweight among Cameroonian women between 2004 and 2011, and identify socioeconomic characteristics associated with these health problems. Data from the 2004 and 2011 Cameroon Demographic and Health Surveys are used. Analyses focus on women aged 15-49, excluding those who were pregnant at the time of surveys. Obesity is defined as a body mass index (BMI) of 30 or higher, while overweight is defined as a BMI between 25 and 29.9. Logistic regression is used for tests for trend. Results highlight a significant increase (p = 0.000) in the prevalence of women obesity from 7.8% in 2004 to 10.3% in 2011. By contrast, no significant increase (p=0.459) in the prevalence of overweight is observed between 2004 (20.6%) and 2011 (21.0%). Living in urban areas, belonging to relatively wealthy households, having a low educational level, being a household head and aged are factors associated with a higher risk of obesity. The prevalence of obesity among women increased significantly from 2004 to 2011. Therefore, more effective prevention and health promotion interventions targeting the most at risk are needed to slow the progression of this health problem.

Biography Hyacinthe T. Kankeu is Ph.D. Student in health economics at Aix-Marseille School of Economics. He has completed his masters’ degree from University of Auvergne, Clermont-Ferrand, France. He has published one paper in Health Research Policy and Systems.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 153 Perez Contreras Irma et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Self-perception of body image and its relationship with body mass index (BMI) higher education students in the area of health in Puebla, Mexico Perez Contreras Irma, Trujillo Diaz Ivan, and Galindo Aguilar Edith University of Puebla, Mexico

Introduction: Knowledge of body image perception is vital for the care of eating disorders in young women. Objective: To compare the self-perception of body image with body mass index (BMI) higher education students in the area of health in Puebla, Mexico. Material and methods: We selected a representative sample of 500 students of the Faculty of Medicine of the Autonomous University of Puebla, of 18-27 years which were asked fill out a questionnaire on body self-perception based on a body imaging instrument previously validated in other studies subsequently anthropometric measures were taken, BMI was calculated. Results: Mean age was 20 years with a maximum age of 27 years and a minimum of 18, standard deviation of 1.38. 4.2% were according to their BMI underweight, 77.4% normal weight, 13.6% overweight and 4.8% obese, according to the WHO classification. Of all the students of BMI as underweight, 14.3% were perceived image with underweight, 85, and 7% normal. Of normal weight, 2.0% were identified with image underweight, 86.0% normal, 11.1% overweight and 0.7% as obese. Of the overweight by BMI, 63.2% were identified with normal images, 29.4% overweight, 7.35% as obese. Of the obese according to BMI, 20.8% were identified as normal, 45.8% overweight and 33.3% as obese. The correlation between as you look and how you like to see you was 36.8%. Conclusion: In this study perceived through the body image of being underweight was minimal normal weight for a significant percentage is perceived as overweight and obese and obese women are perceived overweight and normal. The assessment of body image perception can be an important indicator to guide preventive actions against eating disorders in this population.

Biography Perez Contreras Irma has completed the Master of Public Health in 1988, and Master of Science in Public Health with area of concentration in Epidemiology in 2002, at the National Public Health Institute of Mexico. Currently, she is pursuing a doctorate in Public Health Sciences. She published an article internationally and several nationally. Currently, she teaches and conducts research in the Faculty of Medicine of the Autonomous University of Puebla, Mexico.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 154 Raquel Dacal Quintas et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Obstructive sleep apnea syndrome and metabolic syndrome in thin patients: Characteristics and comparation with patients with overweight and obesity Raquel Dacal Quintas, Tumbeiro Novoa M, Alves Perez M. T, Acuña Fernandez A, Santalla Martinez M. L and Marcos Velazquez P Complexo Hospitalario Universitario de Ourense (CHUO), Spain

Objective: To know the prevalence of obstructive sleep apnea syndrome (OSAS) and metabolic syndrome (MS) in thin patients and their demographic characteristics. We also want to know if there are epidemiologic differences with overweight and obese patients. Methods: We studied all the patients that were referred to our sleep laboratory, from January to December 2009. The patients underwent polysomnography and respiratory polygraphy. OSAS was diagnosed when apnea hipopnea index (AHI) was >5. MS was diagnosed according to the International Diabetes Federation criteria. The patients were distributed in three groups according to their body mass index (BMI): normal weight or thin patients (BMI <25), overweight (BMI 25-29.9) and obesity (BMI ≥30). Results: We studied 475 patients: 7.60% with normal weight, 36% overweight and 56.40% obese. In the group of the thin patients, most of them were women (55.60%), snorers (63.90%), non-smokers (66.70%) and non- drinkers (83.30%). We diagnosed of OSAS 428 (90.10%): in the group of thin patients 77.70%, in overweight 84.79% and in obese 91.40%. Thin patients with OSAS' diagnose were mostly mild OSAS (64.28%), in overweight group were mostly moderate OSAS (41.38%) and in obese group were mostly severe OSAS (57.90%). There were significant differences (p<0.001) between OSAS' diagnose and categorized BMI. We diagnosed of MS 288 (64.40%): in the thin group 33.33%, in overweight 43.94% and in obese 80.93%. We found more probability of MS (p<0.001) with BMI's increase. There were differences between thin group and the others, in the first they were younger with minor neck and waist perimeter (p=0,021; p<0,001; p<0,001).OSAS and MS prevalence in the thin group were 22% and in obese 70.52% (p<0.001). OSAS in thin patients was related with gender (p=0,039, women had less risk) and age (p=0,045, OSAS patients were older). Conclusions: OSAS' prevalence in thin patients is minor than in overweight and obese. OSAS and MS' prevalence in thin patients versus obese patients is minor. Thin patients were more frequently women, younger and without toxic habits. OSAS in thin patients was related with gender and sex, but OSAS and MS were not related.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 155 Javed Akhtar Ansari, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Protective role of Zingiber officinale to curb visceral obesity induced by monosodium glutamate on neonatal Wistar rats Javed Akhtar Ansari MESCO College of Pharmacy, India

Background: In light of the lack of thriving weight-loss treatments and the public-health implications of the obesity pandemic, the development of safe and effective drugs should be a main concern. Aim: The present study was planned to evaluate the alcoholic extract of Zingiber officinaleon monosodium glutamate (MSG; ajinomoto)-induced visceral obesity in neonatal (pups) Wistar rats. Materials and Methods: The Wistar rats were administered subcutaneously with MSG (4 g/kg b.w.) from day 2 to 14 after birth, on alternate days. After attaining six-weeks of age, MSG-treated rats were treated with alcoholic extract of Zingiber officinale(200 and 400 g/kg b.w., orally) or orlistat (10 mg/kg b.w., orally) for 28 days, respectively. Biochemical investigations were done on day 29 apart from weekly body weight assessment. Results: Alcoholic extract of Zingiber officinale produced significant reduction in serum leptin, insulin, glucose, total cholesterol (TC), triglycerides (TGs), lactate dehydrogenase (LDH) levels, and elevation in serum high density lipoprotein cholesterol (HDL-C) levels. Conclusion: Results were comparable positive control drug orlistat, a standard anti-obesity drug, and provide clear evidence that the alcoholic extract of Zingiber officinale treatment offered significant protection against MSG-induced obesity.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 156 Mohamed I. Al-Hazmi et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Application of behavioral treatment program on Saudi obese individual Mohamed I. Al-Hazmi, Abdullah Al-Arfaj, and Moussa I. Mohamed King Saud University, Saudi Arabia

Behavioral treatment for obesity in Kingdom of Saudi Arabia should be the first line of intervention for obese Saudi individuals. This approach recognizes that body weight is affected by factors other than behavior, which include genetic, metabolic, and hormonal influences. The short- and long-term effectiveness of this approach is reviewed. Strategies to regulate weight, even though patients may remain overweight after treatment, including prolonging contact between patients and providers, facilitating high amounts of physical activity, and combining lifestyle modification with pharmacotherapy. This study aims to apply the behavioral treatment of obesity on the Saudi obese individual, its short- and long-term results, and methods to improve long- term weight loss.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 157 Oh Han Boon, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Laparoscopic sleeve gastrectomy as an effective method to achieve rapid weight loss to improve candidacy in a potential renal transplant donor with morbid obesity Oh Han Boon National University Health System, Singapore

aparoscopic sleeve gastrectomy is now widely accepted as a form of primary procedure to treat morbid obesity. There has Lalso been evidence to support laparoscopic sleeve gastrectomy as a safe and efficacious procedure for pre-transplant patients with morbid obesity. However, laparoscopic sleeve gastrectomy to achieve weight loss as a procedure to improve living donor candidacy in morbidly obese patients has not been examined. We report a case of a patient who was initially not an ideal candidate as an altruistic renal transplant donor due to his morbid obesity. This 24-year-old gentleman initially underwent a trial of medical therapy to achieve weight loss but was unsuccessful. He subsequently presented to our bariatric service where he was offered laparoscopic sleeve gastrectomy to achieve weight loss. He has a medical history of allergic rhinitis, hyperlipidemia and mild obstructive sleep apnea. The patient subsequently underwent laparoscopic sleeve gastrectomy with a pre-operative body mass index (BMI) of 36.2 kg/m2. He tolerated the procedure well and was discharged on postoperative day five with no significant perioperative complications. The patient was followed up and achieved significant weight loss of 35 kg with BMI of 24.5 kg/m2 nine months after the surgery. He was reassessed by the transplant team and was deemed to be fit to be a renal transplant donor. The ASA score improved from III to I. The patient subsequently underwent left laparoscopic nephrectomy as a living donor and tolerated the procedure well. There were no immediate post-operative complications and he was discharged well on post- operative day three. Laparoscopic sleeve gastrectomy may be a viable primary bariatric procedure to achieve rapid weight loss to improve candidacy of morbidly obese patients as potential transplant donors.

Biography Oh Han Boon graduated with an MBBS from the Yong Loo Lin School of Medicine, National University of Singapore in 2009. He was awarded the membership from the Royal College of Surgeons in Edinburgh (MRCSEd) in 2013 after successfully completing the membership examinations. He is currently a 2nd year resident in the Residency Program at the National University Health System, Singapore.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 158 Jee-Young Yeon et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

A study on dietary habits, body satisfaction and nutritional knowledge by body image of middle school girl students in Chungbuk area Jee-Young Yeon, Ki-Yong Shin, Hye-Young Lee, Baeg-Won Kang, Hye-Kyung Park and Soon-Kyu Lee Ministry of Food and Drug Safety, Korea

his study was performed to investigate the dietary habits, body satisfaction and nutritional knowledge according to body Timage of middle school girl students (n=284). The subjects were classified to lean, normal and fat groups according to body image. The weight, body mass index (BMI) and the score of present body image of present was significantly higher in the students who recognized their body image as ‘fat’. The satisfaction of body image was significantly lower in students who recognized their body image as ‘lean’. The interest of weight control and experience of weight control were significantly higher in students who recognized their body image as ‘fat’. The necessity of nutrition education was high in all groups ('lean' (67.2%), 'normal' (59.0%) and 'fat' (52.8%)). The frequency of fruit juices and fried food were significantly higher in 'normal' compared to 'fat'. There was no significant difference in the frequency of snack and nutritional knowledge among three groups. Using multiple regression analysis, the score of body image was negatively associated with frequency of snack in the 'lean'. The score of body image was positively associated with identification of nutrition labeling and interest of weight control but was negatively associated with satisfaction of body image in the 'fat'. Therefore, the middle school girl students are needed correct recognition of body image and continuous and practical nutrition education in order to maintain healthy dietary habit.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 159 Abd El Aziz Ali Sherif, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Effect of aerobic exercise with diet control on obesity in children Abd El Aziz Ali Sherif Cairo University, Egypt

Introduction: The purpose of this study was to investigate the effect of regular aerobic exercises with diet control on weight reduction on obese children. Subjects and Methods: Thirty children with overweight (age ranged from eight to twelve years) were included in the study. The children were randomly divided into two equal groups. The exercise group received ten weeks physical activities program included upper limb, lower limb, and trunk and neck exercises as well as running three sessions per week (in the first four weeks the session lasted for about 40 minutes and in the last six weeks the session extended to be 50 minutes. Body mass index and waist-to-hip ratio and waist circumference) were used to assess the children weight before and after three months of the treatment program. Results: The results revealed statistically significant improvement in the measuring variables of both groups when comparing their pre and post treatment mean values. Comparing the two groups’ post –treatment variables, significant difference is revealed in favor of the study group (B) Conclusion: The obtained results strongly support the using of aerobic exercise with diet control as an additional procedure for the weight reduction of obese children.

Biography Abdel Aziz Ali Sherief has completed his Ph.D. at the age of 33 years from Cairo University and postdoctoral studies from Cairo University. He has published more than 10 papers in reputed journals and has been serving as an editorial board member of repute.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 160 Tugli Augustin, J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Knowledge of healthy eating amongst rural secondary school learners in South Africa Tugli Augustin University of Venda, South Africa

Introduction: People are what they eat and how they eat. Certain eating practices predispose people to diseases such as obesity, heart failure, diabetes and hypertension. Healthy eating is a preventative measure against such diseases. Knowledge of what and how to eat is needed of people wish to stay healthy. This study assessed knowledge of healthy eating among rural secondary school learners in South Africa. Objectives: To assess secondary school learners’ knowledge of the number of times a person should eat per day; to assess secondary school learners’ knowledge of the four basic nutrients found in food; and to assess secondary school learners’ knowledge of nutrients supplied by food items. Methodology: This study adopted a quantitative approach using a descriptive survey design. Data was collected from a total of 321 randomly selected learners aged 14-18 years from 10 secondary schools that makes up a rural Vhumbedzi circuit in the Limpopo province using a self-administered questionnaire. Permission to enter the circuit and schools was obtained from the circuit manager and parents/learners informed consent was obtained prior to data collection. Results: The majority (61% of respondents) did not know the recommended number of times people should eat per day. The majority (76% of respondents) knew the four basic nutrients found in food. The majority (98% of respondents) knew that from apples, oranges and banana we get vitamins. The majority (91% of respondents) did not know that from porridge, cornflakes and bread we get carbohydrates. The majority (66% of respondents) did not know that from chicken necks, chicken hearts and beef livers we get proteins. The majority (95% of respondents) knew that from polony and vienna we get a lot of fats. Conclusion and recommendation: Rural secondary school learners in South Africa lack adequate knowledge of healthy eating. Lack of knowledge of healthy eating might lead learners to adopt eating practices that predispose them to diseases such as obesity, heart failure, diabetes and hypertension. Education about healthy eating habits should be intensified in rural schools of South Africa.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 161 Natalia Strueva et al., J Obes Weight Loss Ther 2013, 3:7 http://dx.doi.org/10.4172/2165-7904.S1.012

2nd International Conference and Exhibition on Obesity & Weight Management December 02-04, 2013 Hampton Inn Tropicana, Las Vegas, NV, USA

Dynamics of body weight and mental state of obese patients depending on the associated sleep disorders Natalia Strueva1, Gegel N. V3, Poluektov M. G2, Saveleva L.V1, and Melnithenko G. A1 1Endocrinology Research Center, Russia 2First Moscow State Medical University, Russia 3Moscow Research Institute of Psychiatry, Russia

Aims: Alimentary obesity has a strong comorbidity with sleep disorders. The aim of this research was to estimate the correlation between insomnia and mental disorders among the obese patients. Materials and Methods: 123 patients (51 males and 72 females, age 40.0±11.5; body mass index (BMI) 39.8±8.7 kg/m2) with obesity were included in this study. Patients were divided in two groups: first group consisted from 55 patients with insomnia complaints, second (controls)-68 patients without insomnia. Questionnaire survey of patients was conducted to check their estimates of sleep quality. Psychological features were assessed with the Minnesota Multiphasic Personality Inventory (MMPI) and Hospital Anxiety and Depression Scale (HADS). Mental disorders were diagnosed clinically according to ICD-10 criteria. Results: Subjective problems with quality of sleep were observed in 76%, snoring in 63%, hypersomnia symptoms in 55%, features of sleep apnea in 50%, and insomnia signs in 45% of patients. Insomnia intensity significantly correlated (p<0.03) with dysthymia and mild depressive episode. According to data of psychological testing, obese patients with insomnia had high levels of health anxiety, somatization, depression, displacement and high susceptibility to mental stress. Mean levels of anxiety and depression by HADS were significantly higher in patients with insomnia comparing ones without insomnia (8.8±4.4; 6.5±3.2 vs.7.3±2.8; 5.7±2.5, p<0.01). Patients of the first group more frequently had clinical anxiety and subclinical depression ("Chi- square" (c2)=9.82; p<0.001 and c2=6.98; p<0.008 respectively). Clinically significant weight loss (5% or more of the initial) after 6 months of combined treatment was achieved more frequently in patients without insomnia comparing ones with insomnia (c2=4.91; p<0.03). Conclusion: sleep disorders associated with latent or evident psychopathology affect the extent of weight loss in obese patients.

Biography Natalia Strueva has graduated the Russian National Research State University of Medicine with honors at the age of 25 years. Now, she is a postgraduate student in the Russian Research Center. The subject of her research work is the problem of obesity and the sleep disorders particular. Her scientific supervisors are Prof. Dr. Melnithenko G. A. and Аssoc. Prof. Poluektov M. G.

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J Obes Weight Loss Ther 2013 Obesity-2013 Volume 3 Issue 7 December 02-04, 2013 ISSN: 2165-7904, JOWT an open access journal Page 162