MRPL40 Antibody Cat. No.: 60-027
MRPL40 Antibody
Specifications
HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human
This MRPL40 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 172-200 amino acids from the C-terminal region of human MRPL40.
TESTED APPLICATIONS: WB
APPLICATIONS: For WB starting dilution is: 1:1000
PREDICTED MOLECULAR 24 kDa WEIGHT:
Properties
This antibody is purified through a protein A column, followed by peptide affinity PURIFICATION: purification.
CLONALITY: Polyclonal
ISOTYPE: Rabbit Ig
CONJUGATE: Unconjugated
October 2, 2021 1 https://www.prosci-inc.com/mrpl40-antibody-60-027.html PHYSICAL STATE: Liquid
BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.
CONCENTRATION: batch dependent
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Additional Info
OFFICIAL SYMBOL: MRPL40
39S ribosomal protein L40, mitochondrial, L40mt, MRP-L40, Nuclear localization signal- ALTERNATE NAMES: containing protein deleted in velocardiofacial syndrome, Up-regulated in metastasis, MRPL40, NLVCF, URIM
ACCESSION NO.: Q9NQ50
PROTEIN GI NO.: 21263795
GENE ID: 64976
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic BACKGROUND: ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio- facial syndrome and DiGeorge syndrome.
REFERENCES: 1) Collins, J.E., et al. Genome Biol.(10), R84 (2004) :
2) Zhang, Z., et al. Genomics 81(5):468-480(2003)
3) Kenmochi, N., et al. Genomics 77 (1-2), 65-70 (2001) :
4) Hildebrandt, T., et al. Anticancer Res. 19 (1A), 525-530 (1999) :
ANTIBODIES FOR RESEARCH USE ONLY.
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October 2, 2021 2 https://www.prosci-inc.com/mrpl40-antibody-60-027.html