INDEXED ISSN : 2278-7526 www. snmcbgk.in/medicainnovatica.html

Medica Innovatica Volume 1,Issue 1, July 2012

A peer reviewed medical journal

An official publication of B.V.V.Sangha's S. Nijalingappa Medical College and H. S. K. Hospital and Research Centre BAGALKOT-587102, , . GOVERNING COUNCIL Chief Patron

Shri. Veeranna C. CharantimathMLA Chairman, B.V.V. Sangha, Bagalkot Patrons Shri. Siddanna Shettar Chairman, Governing Council S. N. Medical College, Bagalkot Dr. Ashok S. Dr. T. M. Chandrashekar Principal, S.N. Medical College, S. N. Medical College Bagalkot Bagalkot Editorial Board Editor- in – chief Associate Editors Dr. D. A. Hiremath Dr. Sanjeev I. Kolagi Professor of Anesthesiology Dr. Sangappa V. Kashinakunti S. Nijalingappa Medical College, Dr. Shivakumar Solabannavar Bagalkot -587102, Karnataka, India. Dr. Vijayamahantesh S.N. Dr. Anita Herur Executive Editor Dr. Manjula R. Dr. Ashalata A. Mallapur Dr. Manjunath Editor Dr. Lalita D. Hiremath Local Advisory Board

Dr. B. H. Kerudi Dr. S. Manjunath Dr. B. C. Yelameli Dr. V. D. Domble Dr. E. B. Kalburgi Dr. C. S. Hiremath Dr. Pramiladevi Dr. Geetanjali Dr. Jayashree M. P. Dr. Uday Ambi Dr. Sudheendra Swamy

National Advisory Board Dr. Sriprakash K.S. Dr. Arun Jamakar Dr. Kusal Das Vice Chancellor, Vice Chancellor, Professor of Physiology Rajiv Gandhi University Maharashtra University Al-Ameen Medical college, of Health Sciences, Bangalore of Health Sciences, Nasik Bijapur Dr. S. S. Buggi Dr. R. Chaturvedi Dr. Vishwanath Yemul Director, Rajiv Gandhi Dy. Commandant Medical Administrator Institute of Chest Diseases Command Hospital KEM Hospital, Pune Bangalore Bangalore Dr. Ratnakar Dr. P.S. Shankar Dr. P.F. Kotur Neuropathologist Director, M.R. Medical Registrar, KLE Global Hospital, Hyderabad College, Gulbarga University, Overseas Advisory Board Dr. Jagadish, Anaesthesiologist (UK), Dr. Prakash Kagal, Cardiologist (USA) Dr. Anupkumar S. Orthopedician (UK) Medica Innovatica is an official biannual peer-reviewed indexed medical journal of B.V.V.Sangha’s S. Nijalingappa Medical College, Bagalkot-587102 Karnataka India. It is a multidisciplinary print and electronic journal that publishes original articles, review articles, clinical reports, case studies and brief communications in all fields of medical sciences.

International Standard Serial Number : P- 2278 - 7526

Website of the journal : www.snmcbgk.in/medicainnovatica.html

Indexing Information : Medica Innovatica is Indexed in Index Copernicus Ulrich’s International Periodical Directory Indian Health Science Citation Index Indian ScienceAbstract

Subscription Information : Annual subscription rate - Personal Rs. 1000/- Within India USD 100/- Outside India Institutional Rs. 3000/- Within India USD 200/- Outside India Disclaimer The Editor-inChief disclaims any responsibility for statements made and opinions expressed by authors or claims made by advertisers.

Copyright No part of this journal may be reproduced or transmitted in any form or by any means, electronic or print including photocopying without written permission from editor-in- chief/publisher.

©All rights reserved. Publisher : Dr.A. S. Mallapur Principal, S Nijalingappa Medical College Bagalkot - 587102 Karnataka, India.

Correspondence

All correspondence should be addressed to Dr. D. A. Hiremath Editor in Chief , Medica Innovatica, Professor, Dept of Anaesthesiology S Nijalingappa Medical College, Bagalkot - 587102 Karnataka, India. E-mail : [email protected] [email protected] Instructions for authors

Medica Innovatica

About the journal of the manuscript. Medica Innovatica is a biannual peer-reviewed Manuscripts accepted for publication are copy indexed medical journal published by S. edited for grammar, punctuation, print style, and Nijalingappa Medical College, Bagalkot-587102, format. Page proofs are sent to the corresponding Karnataka, India. author. The corresponding author is expected to Scope of the journal return the corrected proofs within two days. The The journal will cover studies related to all health whole process of submission of the manuscript to sciences, with special preference to those whose final decision; sending and receiving proofs is implications are directed towards improving the completed online. health care of the community, directly or indirectly. Authorship Criteria The editorial process Authorship credit should be based only on A manuscript will be reviewed for possible substantial contributions to each of the three publication with the understanding that it is being components mentioned below: submitted to Medica Innovatica alone at that point 1. Concept and design of study or acquisition of in time and has not been published anywhere, data or analysis and interpretation of data; simultaneously submitted, or already accepted for 2. Drafting the article or revising it critically for publication elsewhere. All manuscripts received important intellectual content; and are duly acknowledged. On submission, editors 3. Final approval of the version to be published. review all submitted manuscripts. Manuscripts General guidelines with insufficient originality, serious scientific or 1. Use only New Times Roman font. technical flaws, or lack of a significant message are 2. UseA4 size paper (Microsoft Office Word). rejected before proceeding for formal peer-review. 3. 20 font for the title of the article. Manuscripts that are found suitable for publication 4. 14 font for the headings which should be bold. in Medica Innovatica are sent to two or more expert 5. 12 font for sub-headings which should be bold. reviewers. The journal follows a double-blind 6. For the text 12 font. review process, where in the reviewers and authors 7. Don’t use capital letters for title and sub- are unaware of each other’s identity. Every headings. manuscript is also assigned to a member of the 8. Double-spacing should be maintained editorial team, who based on the comments from throughout the manuscript. the reviewers takes a final decision on the 9. 2.5cm margins on all the four sides, manuscript. The comments and suggestions 10. Should number all of the pages of the (acceptance/rejection/revision in manuscript) manuscript consecutively, beginning with the received from reviewers are conveyed to the title page. corresponding author. If required, the author is Submission of Manuscripts: requested to provide a point by point response to All manuscripts must be submitted to the editor- reviewers’ comments and submit a revised version in-chief through e-mail ([email protected]) in the form of two separate files:

48 Medica Innovatica Vol. 1 Issue 1 July 2012 Instructions for authors Title Page: The title page should have the Original article following information: The text of original article (observational and 1. Type of manuscript (original article, review experimental articles) is divided into the following article, case report, etc.) sections: Introduction, Material and Methods, 2. Article title. Results, and Discussion (“IMRAD” structure). 3. Arunning head/short title, usually no more than Abstract 60 characters Structured abstracts (250 words)in the form of 4. Authors’ full names and institutional Background, Aim,Material and Methods, Results, affiliations and Conclusion, followed by 3-6 key words are 5. The name of the department(s) and preferred for original research. institution(s) to which the work should be Introduction attributed. Provide a context or background for the study 6. Disclaimers, if any. (that is, the nature of the problem and its 7. Contact information for corresponding authors. significance). State the specific purpose or The name, mailing address, telephone and fax hypothesis tested by the study or observation. numbers, and e-mail address of the author Specify what is already known and what the present responsible for correspondence about the study adds to the literature. manuscript. 8. Source(s) of support in the form of grants, Material and Methods equipment, drugs, or all of these. Mention about the ethical clearance and 9. Word counts. A word count for the abstract and informed consent taken, the details of which should text (excluding abstract, acknowledgments, be produced to the journal on demand. Describe figure legends, and references) should be selection of the observational or experimental mentioned. participants (patients or laboratory animals, 10. Number of figures and tables. including controls) clearly, including inclusion and 11. Conflict of Interest exclusion criteria and a description of the source 12. Clinical trial registry number, wherever population. The guiding principle should be clarity applicable. about how and why a study was done in a particular Article file: The manuscript must not contain any way. Identify the methods, apparatus (give the mention of the authors' names or initials or the manufacturer’s name and address in parentheses), institution at which the study was done or and procedures in sufficient detail to allow others to acknowledgements. This will include the title of the reproduce the results. Give references to article, abstract, introduction and the rest of the established methods, including statistical methods; manuscript. provide references and brief descriptions for The contributors' / copyright transfer form:A methods that have been published but are not well- scanned copy of the original with the signatures of known; describe new or substantially modified all the contributors has to be submitted along with methods, give the reasons for using them, and the manuscript. evaluate their limitations. Identify precisely all drugs and chemicals used, including generic Preparation of the manuscript name(s), dose(s), and route(s) of administration. Manuscripts should be prepared in concordance Describe statistical methods with enough detail with the Uniform requirements for manuscripts to enable a knowledgeable reader with access to the submitted to biomedical journals formulated by the original data to verify the reported results. When International Committee of Medical Journal possible, quantify findings and present them with Editors(http://www.icmje.org/manuscript_1prepar appropriate indicators of measurement error or e.html). uncertainty (such as confidence intervals). Specify

Medica Innovatica Vol. 1 Issue 1 July 2012 49 Instructions for authors

the computer software used. main findings, then explore possible mechanisms The reporting guidelines for each type of study or explanations for these findings, compare and have to be followed, which can be accessed from contrast the results with other relevant studies, state the following sources (as shown in the table the limitations of the study, and explore the below): implications of the findings for future research and Results for clinical practice. Present your results in logical sequence in the Link the conclusions with the goals of the study text, tables, and illustrations, giving the main or but avoid unqualified statements and conclusions most important findings first. Do not repeat all the not adequately supported by the data. data in the tables or illustrations in the text; References emphasize or summarize only the most important The Uniform Requirements style for references observations. Extra or supplementary materials and is based largely on anAmerican National Standards technical detail can be placed in an appendix where Institute style adapted by the NLM for its they will be accessible but will not interrupt the databases. References should be numbered flow of the text. consecutively in the order in which they are first When data are summarized in the results mentioned in the text. Identify references in text, section, give numeric results not only as derivatives tables, and legends by Arabic numerals in (for example, percentages) but also as the absolute parentheses. The titles of journals should be numbers from which the derivatives were abbreviated according to the style used in the list of calculated, and specify the statistical methods used Journals Indexed for MEDLINE, posted by the to analyze them. Restrict tables and figures to those NLM on the Library's Web site.Afew examples for needed to explain the argument of the paper and to writing references are quoted below: assess supporting data. Use graphs as an alternative Journal article to tables with many entries; do not duplicate data in Rose ME, Huerbin MB, Melick J, Marion DW, graphs and tables. Palmer AM, Schiding JK, et al. Regulation of Discussion interstitial excitatory amino acid concentrations Emphasize the new and important aspects of the after cortical contusion injury. Brain Res. study and the conclusions that follow from them in 2002;935(1-2):40-6. the context of the totality of the best available Books evidence. Do not repeat in detail data or other Murray PR, Rosenthal KS, Kobayashi GS, information given in the Introduction or the Results Pfaller MA.Medical microbiology. 4th ed. St. section. For experimental studies, it is useful to Louis: Mosby; 2002. begin the discussion by briefly summarizing the

Initiative Type of Study Source Randomized controlled CONSORT http://www.consort-statement.org trials Studies of diagnostic http://www.consort- STARD accuracy statement.org/stardstatement.htm http://www.consort- Systematic reviews and QUOROM statement.org/Initiatives/MOOSE/moose.pdf meta-analyses statement.org/Initiatives/MOOSE/moose.pdf Observational studies in STROBE http://www.strobe-statement.org epidemiology Meta-analyses of http://www.consort- MOOSE observational studies in statement.org/Initiatives/MOOSE/moose.pdf epidemiology

50 Medica Innovatica Vol. 1 Issue 1 July 2012 Instructions for authors

Chapter in a book throughout, and large enough to remain legible Meltzer PS, Kallioniemi A, Trent JM. when the figure is reduced for publication. Chromosome alterations in human solid tumors. In: Photomicrographs should have internal scale Vogelstein B, Kinzler KW, editors. The genetic markers. Symbols, arrows, or letters used in basis of human cancer. New York: McGraw-Hill; photomicrographs should contrast with the 2002. p. 93-113. background. Journal article on the Internet Photographs of potentially identifiable people Abood S. Quality improvement initiative in must be accompanied by written permission to use nursing homes: the ANA acts in an advisory role. the photograph. Am J Nurs. 2002 Jun [cited 2002 Aug Figures should be numbered consecutively 12];102(6):[about 1 p.]. Available from: according to the order in which they have been cited http://www.nursingworld.org/AJN/2002/june/Wa in the text. If a figure has been published watch.htmArticle previously, acknowledge the original source and Monograph on the Internet submit written permission from the copyright Foley KM, Gelband H, editors. Improving holder to reproduce the figure. palliative care for cancer [Internet]. Washington: Legends for Illustrations (Figures) National Academy Press; 2001 [cited 2002 Jul 9]. Type or print out legends for illustrations using Available from: double spacing, starting on a separate page, with http://www.nap.edu/books/0309074029/html/. Roman numerals corresponding to the illustrations. Homepage/Web site When symbols, arrows, numbers, or letters are used Cancer-Pain.org [Internet]. New York: to identify parts of the illustrations, identify and Association of Cancer Online Resources, Inc.; explain each one clearly in the legend. Explain the c2000-01 [updated 2002 May 16; cited 2002 Jul 9]. internal scale and identify the method of staining in Available from: http://www.cancer-pain.org/. photomicrographs. Tables Units of Measurement Type or print each table with double-spacing on Measurements of length, height, weight, and a separate sheet of paper. Number tables volume should be reported in metric units (meter, consecutively in the order of their first citation in kilogram, or liter) or their decimal multiples. the text and supply a brief title for each. Do not use Temperatures should be in degree Celsius. Blood internal horizontal or vertical lines. Authors should pressure should be in millimeters of mercury. For place explanatory matter in footnotes, not in the reporting hematologic, clinical chemistry, drug heading. If you use data from another published or concentrations, and other measurements, use both unpublished source, obtain permission and local as well as International System of Units (SI acknowledge that source fully. units). Illustrations (Figures) Abbreviations and Symbols Figures should be in JPEG or GIF format total Use only standard abbreviations. Avoid figure size not exceeding 4MB. Authors should abbreviations in the title of the manuscript. The review the images of such files on a computer spelled-out abbreviation followed by the screen before submitting them to be sure they meet abbreviation in parenthesis should be used on first their own quality standards. For x-ray films, scans, mention unless the abbreviation is a standard unit and other diagnostic images, as well as pictures of of measurement. pathology specimens or photomicrographs, send ReviewArticles: sharp, glossy, black-and-white or color The prescribed word count is up to 4000 words photographic prints, usually 127 x 173 mm (5 x 7 excluding tables, references and abstract. The inches). Letters, numbers, and symbols on figures manuscript may have about 50 to 60 references. should therefore be clear and consistent The manuscript should have an abstract (250

Medica Innovatica Vol. 1 Issue 1 July 2012 51 Instructions for authors

words) representing an accurate summary of the article. The section titles would depend upon the topic reviewed. Authors submitting review manuscripts should include a section describing the methods used for locating, selecting, extracting, and synthesizing data. These methods should also be summarized in the abstract. Case reports: New, interesting and rare cases can be reported. They should be unique in providing a learning opportunity for the readers. Cases with clinical implications will be given priority. These communications could be of up to 1500 words (excluding abstract and references) and should have the following headings: Abstract, Key-words, Introduction, Case report, Discussion, References, Tables and figures. This could be supported with upto 10 references. Case Reports could be authored by up to four authors. Letters to the Editor: These should be short and decisive observations. They should preferably be related to articles previously published in the Journal or views expressed in the journal. The letter could have up to 600 words and 6 references. It could be generally authored by not more than four authors. Short communication: The manuscript could be of up to 1000 words (excluding references and abstract) and could be supported with up 6 to 8 references.

52 Medica Innovatica Vol. 1 Issue 1 July 2012 Copyright form

Manuscript Title:

I/we certify that I/we have participated sufficiently in contributing to the concept and design of study or acquisition of data or analysis and interpretation of data; drafting the article or revising it critically for important intellectual content; and final approval of the version to be published, to take public responsibility for it and have agreed to have my/our name listed as a contributor. I/we believe that the manuscript represents original genuine work. Neither this manuscript nor one with substantially similar content under my/our authorship has been published or is being considered for publication elsewhere.If requested by the editors, I/we will provide the data/information or will cooperate fully in obtaining and providing the data/information on which the manuscript is based, for examination by the editors or their assignees. Financial interests, direct or indirect, that exist or may be perceived to exist for individual contributors in connection with the content of this paper have been disclosed. Sources of outside support of the project are mentioned. I/We hereby transfer(s), assign(s), or otherwise convey(s) all copyright ownership, including any and all rights incidental thereto, exclusively to the Journal, in the event that such work is published by the Journal. The Journal shall have the right to print, publish, create derivative works, and sell the Work throughout the world,in all languages and media. The Journal shall own the work, including- 1. copyright; 2. the right to grant permission to republish the article in whole or in part, with or without fee; 3. the right to produce preprints or reprints and translate into languages other than English for sale or free distribution; and 4. the right to republish the work in a collection of articles in any other print or electronic format. We give the rights to the corresponding author to make necessary changes as per the request of the journal, do the rest of the correspondence on our behalf and he/she will act as the guarantor for the manuscript on our behalf. All persons who have made substantial contributions to the work reported in the manuscript, but who are not contributors, are named in the acknowledgment and have given me/us their written permission to be named. Name Signature Date signed 1. ------2. ------3. ------4. ------5. ------6. ------