PRDM2 Antibody Cat. No.: 23-660

PRDM2 Antibody

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Rat

Recombinant fusion containing a sequence corresponding to amino acids 1-240 of IMMUNOGEN: human PRDM2 (NP_036363.2).

TESTED APPLICATIONS: IHC, WB

WB: ,1:500 - 1:2000 APPLICATIONS: IHC: ,1:50 - 1:200

POSITIVE CONTROL: 1) Rat heart

PREDICTED MOLECULAR Observed: 250kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

September 25, 2021 1 https://www.prosci-inc.com/prdm2-antibody-23-660.html CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: PRDM2

HUMHOXY1, KMT8, KMT8A, MTB-ZF, RIZ, RIZ1, RIZ2, PR domain protein 2, GATA-3 binding protein G3B, MTE-binding protein, PR domain 2, PR domain containing 2, ALTERNATE NAMES: with ZNF domain, PR domain-containing protein 2, lysine N-methyltransferase 8, -binding zinc finger protein, retinoblastoma protein-interacting zinc finger protein, zinc finger protein RIZ, zinc-finger DNA-binding protein

GENE ID: 7799

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

This tumor suppressor is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, , and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a BACKGROUND: role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 25, 2021 2 https://www.prosci-inc.com/prdm2-antibody-23-660.html