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BLANK AUGUST 2020 COVER:FEBRUARY 2007 COVER 12/8/20 16:09 Page 1 NOAIN NFO EHOOYISE8 UUT2020 AUGUST 88 ISSUE TECHNOLOGY FOOD IN INNOVATIONS

ISSUE 88 AUGUST 2020

In this issue: Plant-based meat Health benefits of Collagen peptides and dairy alternatives Dairy protein in healthy ageing Human milk oligosaccharides Anti-inflammatory ingredients and asthma • Curcuma Probiotics for stress relief Waxy potato starch Supplement innovation Organic ingredients Benefits of almonds The vegan diet Fruit & vegetable Yeast cultures powders

SHOW PREVIEWS: SPECIAL FOCUS: Virtual Vitafoods Expo The Belgian Health and Free From Ingredients Group www.innovationsfood.com INFT MEDIA NEW DESIGN 2020:Layout 1 12/8/20 17:32 Page 7

Editorial Calendar 2020-2021

NOVEMBER 2020 FEBRUARY 2021

Food colours Emulsifiers Healthy snacking Heart health Savoury ingredients Healthy ageing Innovative colours Sustainability Plant-based ingredients Sustainability Beauty from within Clean labels Healthy fats + oils Flavoured water Plant-based nutrition Organic superfoods Stress management Increasing satiety Sauces and dressingNatural sweeteners Sports nutrition Gut health Alternative proteins Sports nutrition Allergy detection Joint health Savoury ingredients Emulsifiers Beauty from within Antioxidants Stabilizers Probiotics Sugar replacements Food traceability Capsule technology Ice cream ingredients Probiotics Supercritical extraction techniques and applications Dressings and sauces Ancient grains Fruit flavour profiles for beverages The rise of plant-based ingredients as meat replacers Supply chain transparency Insect nutrition and applications Non-dairy milk ingredients Reducingthe carbon footprint Non-alcoholic beverage ingredients Micro-encapsulation techniques Plant-based foods Ingredients for functional drinks Chocolate and cocoa products PREVIEW: PREVIEWS: The Ingredients Show & Foodex 2021 FiE, Frankfurt, Germany NEC, Birmingham, UK Vitafoods Asia

Deadline: October 23 2020 Deadline: 29 January 2021

MAY 2021 AUGUST 2021

Weight management Boosting immunity Ice cream ingredients Cognitive health Joint health Spices & herbs Alternative proteins Sustainability Infant formula ingredients Algae Mediterranean diet Probiotics Stress management Bone health Healthy snacking Eye health Muscle recovery Eye health Fat substitutes Oat ingredients Improving digestion Muscle recovery Health benefits of spices Micro-algae Cognitive health Probiotics Natural preservatives Allergen detection Improvingdigestion Enhancingtexture Ingredients for sports drinks Ice cream ingredients Salt replacements Chocolate and cocoa products Vegetarian capsules Mediteranean diet Anti-inflammatory ingredients Plant-based ingredients Ancient grains Sugar replacements Ready-made meal ingredients Coconut-based products Mushroom ingredients & applications Processingtechniques for plant extracts Adaptogens (replacing antioxidants) Advances in micro-encapsulation Stress management Enhancingimmunity Infant formula ingredients PREVIEW: Plant-based ingredients Vitafoods Europe 2021, Geneva, Switzerland

Deadline: 9 April 2021 Deadline: July 31 2021

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NEWS

6 ABITEC Corporation acquires Larodan AB Research grade lipids

8 Seeds of growth: Lycored more than doubles Lycopene 17 ASHCROFT COURT • BURNHAM • BUCKS • SL1 8JT production UNITED KINGDOM 9 Brenntag Food & Nutrition opens new Application & Development Center in Brazil EDITORIAL Tel: +44 (0)1628 666176 Email: [email protected] 10 DKSH partners with Kemin Food Technologies in Vietnam, Myanmar, Cambodia and Singapore ADVERTISING Tel: +33 4 66 580 562 • Fax: +33 (0) 97 06 29 185 Email: [email protected] 12 Synergy Flavours increases production capacity in Asia with new high-care blending facility ISSN1465 - 0460 13 BENEO invests €60 million in increasing capacity at Wijgmaal rice starch plant

Advertising and Business Development Director David Copperfield 84 Study news round-up Tel: +33 466 580 562 Fax: +33 (0)97 06 29 185 Email: [email protected]

Advertising and Publications Director: Terry Prior INGREDIENTS FEATURES Email: [email protected]

® ® Subscriptions: 14 Meriva : The Indena’s turmeric phytosome for an effective, total wellbeing Email: [email protected] Indena

16 Keep on moving: The power of collagen peptides GELITA

Published by Print Workshop Publications Innovations in Food Technology is published quarterly in 18 Consumer experience key to growth of plant-based February, May, August and November meat and dairy alternatives market Informa Markets

20 The future is NOW: Introducing Vitafoods Virtual Expo and Summit shaping profound connections in the Subscriptions: digital age Informa Markets Printed version: UK: £50.00 + VAT (inc postage) Europe: £65 Euros 90.00 (Airmail including p+p) 22 In touch with nature Kanegrade Rest of the World: £75.00 USD125.00 (Airmail including p+p) Online only: £25.00 25 Stress relief in a probiotic stick DuPont

26 Responsible product design: helping consumers live © copyright by Innovations in Food Technology. better through trend-driven supplement innovation All rights reserved. Lonza No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means 28 Fi Europe co-located with Hi Europe will employ the without the prior written permission of Print Workshop highest hygiene and safety standards Publications Informa

30 Dairy protein and its role in the health of elderly people Ingredia PRINT WORKSHOP 32 Planning for the day after: Future-proof food PUBLICATIONS ingredients for thought LIMITED Almond Board of California

4 Innovations in Food Technology August 2020 www.innovationsfood.com | | CONTENTS:TESTING 13/8/20 14:21 Page 3 Contents ISSUE 88 AUGUST 2020

70 Why is everyone going vegan? 33 HMOs and asthma Viva! Jennewein DAIRY 36 Emsland Group offers new waxy potato starch solution Emsland Group 72 China health authorities acknowledge L.helveticus Rosell®-52, B. infantis Rosell®-33 and B. bifidum 38 Is collagen the way forward for the joint health Rosell®-71 for safe use in infant formula market? Rousselot

74 DuPont Nutrition & Biosciences drives dairy industry 42 Demand for organic ingredients surges in the wake of innovation with Chymostar™ cheese coagulant coronavirus pandemic BENEO

75 New recipes for sweetened condensed milk and 46 Wagralim investment in new packaging equipment The Belgian Health Ingredients Group

55 Create a visual feast with food colouring! BAKERY NEWS Cornelius

56 Anti-inflammatory activities of Naticol® demonstrate 62 Lantmännen Unibake expands in Norway benefits in ageing Weishardt International 62 KaTech launches new brand for low dosage bakery concen- trate 58 Cultures that matter Lallemand Health Solutions

62 NUTREVENT 2021 NEW INGREDIENTS SHOWCASE Nutrevent

78 Plant-based colours can give plant-based products the 64 Sabinsa earns non-GMO project verification for eleven edge – EXBERRY® Coloring Foods supplier GNT key ingredients Sabinsa 80 Cargill offers new addition to sweetener portfolio to food and beverage manufacturers 65 Clean label dietary shakes with SANACEL add 045 CFF 82 Fish alternatives – The new heroes of the plant-based revolution 68 Free From Functional & Health Ingredients North Edition is returning to Amsterdam

IMPORTANT NOTICE TO CONTRIBUTORS

November 2020 issue Fi & Ni Europe 2020 will be covered in this issue

Innovations in Food Technology will be distributed at this trade show

The deadline for editorial and advertising contributions for this issue is October 23

www.innovationsfood.com | August 2020 | Innovations in Food Technology 5 GEN NEWS:TESTING 13/8/20 14:23 Page 2

ABITEC Corporation acquires DSM and Avril Larodan AB Research grade lipids complete

BITEC Corporation has announced that and lipids, and I look forward to us working together creation of joint it has acquired Larodan AB, a manufac- to grow and expand their brand in the US markets turer and international marketer of state and across the globe,” said Jeff Walton, CEO of venture to of the art, high-purity research grade lipids. This ABITEC. “The acquisition will undoubtedly bring strategic acquisition will expand ABITEC’s functional ABITEC to the forefront of the high-purity lipid lipid product offerings and scientific capabilities to market. develop better serve the pharmaceutical, nutritional and It will also advance ABITEC into the field of industrial market sectors. Lipidomics which has the potential to offer plant-based Located at the globally recognized Karolinska researchers unparalleled capabilities to identify the Institute in Stockholm, Sweden, Larodan is known numerous roles of lipids across a vast spectrum of for its outstanding product quality, customer- health and disease states at the chemical level. protein friendly approach and extensive collaborations with Together, the companies will create a global academic and industrial researchers. “Larodan is a science-based organization that will use product oyal DSM and Avril, have announced the world leader in the field of analytical-grade lipids innovation to propel ABITEC’s scientific and launch of their joint venture, Olatein, to and their scientific capabilities will not only expand commercial interests to new heights. “We are very produce canola (rapeseed) proteins for ABITEC’s technical expertise but will also provide us happy to find a new home with ABITEC, with whom the global food market. One year after announcing with a strategic R&D location in Europe. The Larodan we share a deep interest in lipids. Together we can their intention to work together, Avril and DSM team has done an exceptional job in the develop- immediately offer a more comprehensive service have finalized their partnership and will begin ment, manufacturing and global commercialization to our American customers including, larger construction on a manufacturing facility in Dieppe, of their unique and highly specialized lipid reagents volumes and GMP grades,” said Fredrik Lindgren, France. and we are thrilled to have them join the ABITEC selling shareholder and continuing Managing Protein is a crucial part of a healthy diet. As the team. We share a common passion for innovation Director of Larodan. world’s population heads towards 10 billion by 2050, more protein will be needed that is produced within planetary boundaries. To help meet the growing demand for proteins, DSM and Avril have established a partnership (75/25) and formed Olatein. The partnership draws on the unique know-how of each of the partners, Bunge Loders Croklaan expands including DSM’s patented process and technology for extracting high-quality protein from canola global innovation network meal and Avril’s 35-year legacy in oilseed and protein crop production. s part of its focus on Turkey, the Middle And Turkey is not the only growth market. Data The resulting product, CanolaPRO™, will be East and North Africa, Bunge Loders from Innova Market Insights points to a Middle marketed and sold by DSM. CanolaPRO™ has Croklaan (BLC), a world leader in edible Eastern population with a growing sweet tooth. The excellent functional properties, a high nutritional oils and fats, is expanding its worldwide innovation global research group noted an increase in product value, and a balanced taste profile. It enhances network with its first Creative Studio in the region to launches for bakery and confectionery of +23% and vegan and vegetarian products such as meat and serve its customers in the region. The studio will be +20%, respectively, when comparing 2018 and dairy alternatives, as well as other beverages, baked adjacent to the Bunge Turkey office. 2019 launches, with chocolate and biscuits being products, bars, and ready-to-mix products. “Our goal is to be close to our customers and the top categories. There is also an upswing in To facilitate the production, Avril is investing in work with them to streamline product develop- innovation. Fusion of regional flavors in biscuit and the upstream part of the business, capitalizing on ment and time-to-market,” says Renee Boerefijn, cakes such as halva, hummus, and labneh cheese is its leadership in oilseed crushing and seed sourcing. Director of Innovation EMEA for Bunge Loders trending. The Group will supply Olatein with non-genetically Croklaan. “Whether pioneering products with a modified canola meal from the new crushing unit balanced nutritional profile or creating more Capturing food trends that will be created on the site. The new facility will indulgent treats, our Creative Studios help our The Istanbul Creative Studio will be managed also include a biomethane production unit, which customers stay ahead of the competition. They are by Öznur Köse, Application & Technical Support will contribute to supplying the local public energy the physical representation of the concept, ‘Let’s Manager Turkey, supported by a local team of network and minimize the environmental footprint create together,’ which is fundamental to who we experts, and is the latest addition to the existing of production. are as a company and to our commitment to global network of Creative Experience Centers. It "This partnership with DSM is part of Avril's innovation. A number of new studios are in the will serve to develop solutions with food manufac- strategy to develop and conquer new markets, pipeline, all designed to guide our regional turers across bakery, confectionery, culinary, and with the aim of structuring a new high-protein customers toward effective translation of ideas into dairy in collaboration with innovative networks such seed sector and thus contribute to increasing winning new products.” as Le Cordon Bleu. It will also provide training in France's and Europe's protein self-sufficiency. This The state-of-the-art studio is a dynamic work- specific ancillary issues, such as reformulation of project, in line with our commitments, offers a shop environment that provides on-site support to products according to new regulations including new future for the Dieppe site, while repositioning regional confectionery and bakery manufacturers SAFA, trans-fats, and food safety. it on a new activity that will bring growth and to co-create innovative new products with sensory “Working with a team of dedicated experts in industrial sustainability," said Jean-Philippe Puig, appeal, vibrant new flavors, and enhanced total one of our Creative Studios is an exhilarating Chief Executive Officer of the Avril Group. nutritional value while staying ahead of constantly experience,” enthuses Köse. “The new studio in Is- “With the global population continuing to evolving trends, supporting them in the design of tanbul is now part of Bunge’s extensive network in grow and the demand for healthy and nutritious exciting new solutions to meet regional tastes. Turkey. This allows us to serve regional customers proteins on the rise, the world needs sustainable on a broad range of oils, fats and specialty solutions. Our partnership with Avril enables the Middle East’s growing appetite for solutions.” production of CanolaPRO™, a high-quality and innovative products The official opening ceremony of the new nutritious protein that supports our customers to According to Euromonitor, Turkey’s overall studio is scheduled for October, 2020. The provide consumers around the world with better confectionery market is worth an estimated $3.5B company is looking forward to meeting both its tasting, more enjoyable meat and dairy alterna- and is expected to increase 14.3% in value by the new and existing regional customers at the event. tives—in line with the market trends,” said Patrick end of 2021. Turkey makes up a big part of Eastern The site has been sterilized and workshops will take Niels, President of DSM Food Specialties. Europe’s entire candy market, with an 11.5% share. place in accordance with all Covid-19 directives.

6 Innovations in Food Technology | August 2020 | www.innovationsfood.com The biggest event in nutraceuticals is launching online

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Seedsof growth: Lycored more than doublesLycopene production ycored, a global leader in lycopene-based “These changes ensure that we have the colour and taste-enhancing ingredients expertise and the capacity to meet the needs of for food and beverages, has expanded its our customers across the food, beverage and tomato-based lycopene production to meet health ingredient industries looking for natural unprecedented demand. colour, active health ingredients and taste-enhanc- The company will now harvest record volumes ing solutions.” of tomato annually for its colour and health Lycored also plans further expansion to its © Getty Images ingredient portfolio following a three year multi- seasonal capacity through working with a third party million-dollar investment in new lines, equipment in the Southern hemisphere to provide higher and process and supply optimization strategies. product availability at different times of the year. Azelisextends Lycored’s colour formulation capabilities will be Rony added: “The demand for natural colour a central part of the expansion driven by its new ingredients is higher than ever and continues to formulation facility in Branchburg, New Jersey. The grow as clean label, traceable, vertically integrated distribution new plant will increase the company’s current pigments that are plant-based grow in popularity, colour formulation capacity, reducing carbon alongside the plant-based movement towards a agreement with footprint, and support expansion and supply into more sustainable future. additional markets in Asia and the Middle East. “As manufactures and developers look to Kerry for the Rony Patishi-Chilim, CEO at Lycored said: “The capitalize on this trend, we are ready with our port- expansion of our lycopene production follows a folio to support their projects. Our new Branchburg Polish meat period of strategic equipment investments and facility will also be the location for an application improvements in tomato usage during key harvest laboratory to support colour application and proof market periods. stability initiatives.” zelis is excited to announce an extension of its distribution agreement with Kerry, a global leader in taste and nutrition serving the food, beverage and pharma industries. Effective immediately, Azelis will distribute Kerry’s Unilever and Algenuity partner to solutions for the meat industry on the Polish market. This agreement builds further on the ex- explore the nutritional goodness isting partnership between the two companies. As a long-term distribution partner of Kerry in Europe, Azelis has demonstrated steady organic of microalgae to the table growth, stimulated by its strong formulation expertise. Azelis’ innovation capabilities as well as nilever and biotech start-up Algenuity chlorophyll content of microalgae while still allow- their extensive product knowledge and experience have announced a new partnership to ing them to retain their natural nutrients. This were vital for Kerry to choose Azelis for this delve into the huge potential microalgae unlocks a wealth of potential applications for specific new territory. bring in innovating future foods for Unilever’s plant- microalgae in the food and beverage sector. It Renata Bugiel, Regional Managing Director based portfolio. Algenuity, which specialises in brings the opportunity to develop a sustainable Azelis Poland & Ukraine, comments: “This distribu- developing microalgae for use in consumer source of protein that meets increasing consumer tion agreement allows us to further expand our products, will work with the R&D team within demand for nutritious foods that taste great. footprint in the meat sector in Poland, following Unilever’s Foods and Refreshment (F&R) division “Microalgae offer much untapped potential as our acquisition of Euroconsultant last year which to explore ways of bringing foods made with mi- a viable, climate-friendly protein alternative,” says enhanced our position in the smoke flavour croalgae to the market. Alejandro Amezquita, Future Bio-based Ingredients market. Our skilled team of sales people and lab Developing alternative protein sources like R&D Director, Unilever F&R. “They have a significant experts in Poland are very excited to present our microalgae represents a significant step forwards in part to play in food system transformation. We are expanded product portfolio to our meat the critical shift needed to an equitable and resilient very much looking forward to working with customers” food system. By 2050, the world will need to Algenuity to explore the possibilities of making Michał Stachowiak, Regional Commercial produce 70% more food to feed a growing foods that contain microalgae more mainstream.” Director Kerry Poland, Ukraine & Baltics, comments: population of 10 billion people. These foods will Andrew Spicer, CEO and Founder of Algenuity “For more than 20 years, Kerry has been operating need to meet a high nutritional standard, while says: “We are delighted to partner with Unilever on in Poland through multiple sales channels, working reducing their impact on the environment. this. Our Chlorella Colours® platform provides plant- directly with customers as well as indirectly via Unilever and Algenuity recognise the key role based ingredients that are sustainable, natural, distributors, supporting the local food and that diverse, plant-based proteins like microalgae non-GM and protein-rich with neutral flavours. They beverage industries such as meat, bakery, con- will play in transitioning towards this new food are also vegan-friendly making them extremely fectionery, beverages, dairy and savory products. system. Chlorella vulgaris, a widely recognised relevant for today’s growing consumer appetite for Building a secure and high-functioning distribution (micro)algae, is a nutrient-rich, plant-based source more plant-based foods with additional functional channel for Kerry’s meat industry-dedicated of protein and fibre, with a low environmental foot- benefits.” solutions has been identified as a critical success print. Chlorella possesses a number of additional “We are very excited about the huge potential factor, and thus selecting the right distribution beneficial nutrients including antioxidants, vitamins, working with Algenuity brings to advance nutritious partner for the local meat industry has been of minerals and essential fatty acids. It has been foods that taste great and are a force for good,” immense importance to Kerry. We are very happy consumed globally for many years, yet its high says Manfred Aben, VP Science & Technology R&D to have found that partner in Azelis. Kerry’s vast chlorophyll content, which gives plants their green and Site Leader of Hive, Unilever’s Global Foods and innovative portfolio of meat technologies and colour and a bitter taste and smell, has proven a Innovation Centre, in Wageningen. “Transitioning to solutions enables Azelis to further enhance its barrier to its inclusion in mainstream diets. a sustainable food system requires all of us to work customer service providing a combination of together. It’s one of the world’s greatest challenges signature taste, texture, functionality, improved Innovative technology unlocks new and will not happen without partnerships and nutrition and clean label formulations. Working potential collaborations. This is what our Hive ecosystem is all with Azelis helps us to extend our existing presence Algenuity has developed an innovative tech- about. We are delighted to welcome Algenuity to on the Polish meat market and we are confident nology to overcome this limitation. Its Chlorella our community.” that Azelis’ reach and know-how is a very Colours® palette significantly reduces the important asset for us in this regard.”

8 Innovations in Food Technology | August 2020 | www.innovationsfood.com GEN NEWS:TESTING 13/8/20 14:24 Page 5

Brenntag Food & Nutrition opens Chr. Hansen new Application & Development completesUAS Center in Brazil Labs acquisition

renntag Food & Nutrition has opened its times, Brenntag Food & Nutrition shows its hr. Hansen Holding A/S has announced newest Food Application & Development commitment to support our customers around the the successful completion of the Center (FADC) in Guarulhos, close to Sao globe, adapting to the local needs while leading acquisition of UAS Laboratories LLC (“UAS Paulo in Brazil. This opening marks the 30th FADC with novel applications in line with the market Labs”) following the satisfaction of all closing for Brenntag Food & Nutrition globally. It joins the trends” says Tomás Navarro, Vice President conditions. existing network to bring the formulation and Brenntag Food & Nutrition Latin America. With UAS Labs, Chr. Hansen further strength- application know-how of Brenntag Food & The FADC is equipped with all necessary state- ens its microbial platform and Human Health Nutrition to the region. The fifth FADC for Latin of-the art equipment and special items such as a business by moving into the highly attractive space America will particularly support the Brenntag F&N photostability and fermentation chamber as well as of multi-species, high-potency blends and teams in Brazil and the South Cone in the following a texturometer allowing the team to cater to the broadening its product offering and customer segments: beverages, bakery, dairy, chocolate & individual needs of the customers in order to bring base. Furthermore, Chr. Hansen is expanding its confectionary, sauces, meat, convenience food as products to the market that address key trends. manufacturing footprint with two GMP facilities in well as functional food and food supplements. This new facility is an excellent opportunity for the United States which will allow phasing of capex “This new FADC will develop solutions and new the Brenntag Food & Nutrition team in Brazil to projects over the coming years and reduce enter- technologies to satisfy our customer’s needs and offer their customers even more tailored-made prise risk. demands particularly for the Brazilian market. With services and individual product development Mauricio Graber, Chief Executive Officer of this new investment also in these more challenging solutions. Chr. Hansen, said: “With closing of the UAS Labs acquisition, we look forward to building upon the strengths of both companies. We will expand our probiotic offerings from strain to solution, gain access to new customer groups and move into new indication areas whilst staying true to our Robertet and Klersun agree joint commitment to science and R&D. We are really excited to welcome the team from UAS Labs to the venture with Alponics Chr. Hansen organization and will pursue a ‘best of both’ approach for the integration to create value obertet and Klersun, strategic global part- highest level of traceability and transparency to the for customers and shareholders. I am convinced ners in hemp oil extraction, formulating Swiss customers of food & beverage, nutrition, that together we can truly shape the global and sales, have agreed to a joint venture supplement, cosmetics and pharma, who want to probiotics market for the future.” with Alponics, a Swiss based CBD/hemp production use CBD and hemp extract solutions in consumer Acquiring UAS Labs is fully in line with Chr. company, to expand cultivation and processing of products”, says Alan James Chaytor, Alponics. Hansen’s strategy and capital allocation framework hemp oil extracts for the Swiss market. Hemp extracts, in particular cannabidiol (CBD), of pursuing bolt-on acquisitions to strengthen its The combination of Alponics’ state of the art have emerged quickly on the global market as a microbial platform. UAS Labs has been acquired infrastructure, Klersun’s capability in hemp cultiva- beneficial functional ingredient to general health from the private equity fund Lakeview Equity tion, extraction and science and Robertet’s natural and wellness. “While there is much more research Partners, management team and other share- ingredient leadership and market expertise allows that needs to take place in order for the hard sci- holders at a transaction value, net of tax assets, of the new joint venture to meet the highest quality ence to catch up with the consumer enthusiasm USD 530 million. Leverage will increase short-term demands of the Swiss market and for companies and demand, we are excited to lead in both this re- to around 3x net debt/EBITDA by the end of wanting Swiss made hemp extracts for use in their search and providing our customers with the safest financial year 2019/20, but Chr. Hansen is aiming to products. and most effective hemp extracts to use in their bring down net debt to a level consistent with a “By vertically integrating in Switzerland with products”, says Olivier Maubert, Robertet. solid investment grade rating.slightly accretive. Robertet and Klersun, we will be able to provide the

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Innovations in Food Technology | August 2020 | www.innovationsfood.com 9 GEN NEWS:TESTING 12/8/20 16:23 Page 6

DKSH partners with Kemin Food Technologies in Vietnam, Myanmar, Cambodia and Singapore

KSH Business Unit Performance logistics, in-depth market insights and proven track Materials has become a key distribution record in marketing, sales and distribution in Asia. partner for Kemin Food Technologies in DKSH supports customers for product develop- Vietnam, Myanmar, Cambodia and Singapore. ment, quality improvement and fortification. The Under the new agreement, DKSH will provide partnership with Kemin enables DKSH to provide marketing and sales as well as distribution and customers with shelf-life and food safety solutions logistics for Kemin’s range of both natural and through its state-of-the-art food and beverage Lallemand synthetic antioxidants and shelf-life extension innovation center network across Asia. solutions. “We are very pleased to partner with Kemin Health Solutions Antioxidants can enhance food products by Food Technologies in three South East Asian delaying oxidation, extending shelf life and markets. Combining Kemin’s products and services maintaining freshness, flavor, texture and colour with DKSH’s deep technical know-how and close a major quality. Kemin Food Technologies’ team of distribution capabilities will bring great advantages scientists develops food protection solutions to to our large customer base in the region,” said licensing deal combat challenges encountered in food manufac- Thomas Sul, Co-Head Business Unit Performance turing and processing. Materials, DKSH. DKSH was chosen for its strong capabilities in with Proge Farm®

allemand Health Solutions and Proge Biosyntia secures commercial Farm ® are proud to announce that they have just closed a major licensing deal in-licensing rights to natural for the commercialization by Lallemand Health Solutions of Proge Farm®’s established probiotic strain L. plantarum P17630 (Proge 17630®), which isoflavonoids through has specific women health benefits. “Proge Farm® highly documented probiotic strain L. plantarum P17630 (Proge 17630®), is a global partnership valuable new asset in Lallemand Health Solution’s Women’s health probiotic range. Women’s health ome dietary supplements consist of costly partnerships with other ground-breaking biotech is gaining more importance in the probiotics ingredients made from plant extract. Such companies. It enables us to in-license different market as consumers are increasingly looking for extracts typically have low purity of the compounds and fast-tracking our product pipeline natural ways to take care of their intimate health. active ingredient of interest and can hold harmful efficiently.” Furthermore, with this specific strain, it will be even co-extracted compounds. But thanks to a new easier to do so with one daily dose taken orally” partnership between Danish biotech company Protection against age and declares Isabelle Champié, Vice-President Sales and Biosyntia and French biotech start-up Lantana, we lifestyle-related diseases Marketing at Lallemand Health Solutions. are moving closer to offering natural isoflavonoids While Biosyntia will bring the product to scale “We are proud of this significant licensing made from a more pure and high quality process and commercialize, Lantana supplies its proprietary commercialization agreement with Lallemand that is also cheaper and more sustainable. microbial engineering platform for natural aromatic Health Solutions, a worldwide renowned key player compound production. The natural isoflavonoids in the probiotics industry. They will have the ability In-license for faster pipeline development are made through Lantana’s state-of-the-art to broadly disseminate our strain L. plantarum For Biosyntia, this collaboration is a result of an engineering and fermentation process and are P17630 (Proge 17630®); meaning more women increased focus on in-licensing new technology. associated with a number of human health will benefit from its compelling effects” affirms This makes it possible for the company to develop benefits, such as protecting the body against age Giancarla Dondi, owner and chief executive officer commercially viable nutraceuticals produced from and lifestyle-related diseases. at Proge Farm®. sugar through a more sustainable, fermentation- At Lantana, CEO Michael Naesby is excited Probiotics for women’s health is a fast growing based production process. The uses for these about the new partnership as well: “The collabora- niche as probiotics are seen as a natural alternative ingredients are many, as they form the basis of both tion with Biosyntia allows the speedy development to the conventional solutions and women are everyday dietary supplements, food and beverage of our joint isoflavonoid product line, the first in a willing to try them out especially when hit by fortification as well as personal care products. wide range of natural aromatic ingredients for the reoccurring pains and infections, such as “This exciting partnership with Lantana will nutraceuticals, dietary supplements and personal those associated with vaginal health (Lumina enable us to more rapidly expand our pipeline of care markets,” he says and continues: “Isoflavonoids Intelligence). new and natural ingredients. Given that it typically are a group of aromatic compounds found in soy “Once again, we have a demonstration that requires substantial capital investments to develop bean, red clover and other plants. They have been cooperation spells success. Within our teams as and commercialize new bio-based ingredients, we associated with a wide range of preventive human well as with our partners and customers, we believe that collaborations like this one are the health benefits, which include protection against achieve more together. Through our research and path forward to rapidly increasing the number age-related diseases such as cardiovascular disease, development, our innovation, our technical and of commercial bio-based ingredients,” Martin osteoporosis, hormone-dependent cancer and loss manufacturing expertise, our commitment to Plambech says and continues: of cognitive function, as well as lifestyle diseases quality, our ethics and passion, we keep enhancing “That’s why we at Biosyntia are continuously such as diabetes.” lives in countless ways with probiotics.” concludes focusing on initiating new collaborations and Isabelle Champié.

10 IInnovations in Food Technology | August 2020 | www.innovationsfood.com FOT 11:Layout 1 12/8/20 17:35 Page 1

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DuPont drives planet forward solutions for plant-based food and beverages

anisco Planit™ marks the latest evolution beverages in every meal, every day—from early-bird Synergy Flavours in DuPont’s plant-based ingredient breakfast to the midnight snack.” portfolio – a comprehensive range of Borch sees plant-based as an opportunity for increases functional ingredients and application expertise for the industry to meet consumers’ changing eating food and beverages made with a ‘planet forward,’ habits. sustainable approach. “We believe co-creation is the route to shape production With the new Danisco Planit™ range, DuPont the market and capture fast-evolving consumer Nutrition & Biosciences (DuPont) offers food and needs for every eating occasion,” Borch said. “We capacity in Asia beverage manufacturers the broadest selection of want to create sustainable consumer loyalty, ingredients for plant-based product development ensuring that plant-based products are loved and in the industry, supported by expert application tasty enough to become a regular part of with new knowledge and insights to design products for the consumers’ diets, not just a ‘try it once’.” future. Customers leveraging DuPont’s innovation high-care capabilities in the plant-based segment will be ahead of the curve in managing their global foot- print. blending facility “We named this new brand Danisco Planit™ as an acknowledgement that when scaling up this ynergy Flavours (Thailand) Ltd., has industry it must happen in a sustainable way,” announces the completion of a new explains Birgitte Borch, VP of Marketing, Food & high-care blending facility which has been Beverage, DuPont Nutrition & Biosciences. added to its existing production site in Samut DuPont has decades of experience in the plant- Prakarn, Thailand. based sector, providing support in every step from Equipped with a ribbon blender and an air conceptualization to successful commercialization shower, the new facility adds capacity allowing of innovative, yet locally relevant solutions and ntering a new chapter this year, Synergy to produce powder blended flavours and recipes that are ready to take to market. Fi Europe, the world’s leading event for mixes to address the growing demand in Asia for “The depth of what we can offer our food & beverage ingredients will be sports nutrition beverages, baby infant formula customers is unique in the industry,” Borch said. co-located with Hi Europe, its counterpart for and sweet flavoured functional mix drinks. “Danisco Planit™ is a significant launch for us. We health ingredients, and alternate between The new high-care blending facility adds offer a total ingredient solution with the ability to Germany and France. Combining forces means a 2500m2 of additional space to the Thailand plant. deliver taste, texture, nutrition and sustainability. most comprehensive event bringing together the The clean and low contamination environment is And, we believe in co-creation and look forward to entire global food & health ingredients supply chain suitable for low microbial level products and sweet innovating new formats and categories with our together. powder blended products. The facility will produce customers to widen the food space and create This year’s Frankfurt edition is expected to high quality flavours for sports nutrition beverages, great eating experiences for the growing group of host over 27,000 attendees, looking to network sweet powders blended for beverage and bakery, global consumers that want to increase their and source from 15,000+ ingredients and dairy flavours: milk, cream, cheese, butter mouth- plant-based consumption.” solutions showcased by more than 1,700 feel booster/replacer, instant beverage mixes and exhibitors. With a legacy of over 30 years, the infant follow-on formula. Capturing mainstream consumers event is also known as a hub for food and Synergy will also use the new blending facility For the past couple of years, the plant-based beverage insights and innovation, offering a wide to manufacture its Dairy by Nature range of space has been a race to get on the shelves for variety of content onsite, including conferences, flavours for the bakery, beverages, and cheese both foodservice and retailers. Now it’s about workshops, master classes, and more. market segments. This new range combines staying there and growing further by offering a Top show highlights at this year’s edition Synergy’s all-natural flavour creation expertise with greater variety of categories. include: the proprietary dairy technology of its parent “The market innovation for products that allow New Product Zone company, Carbery, which has more than 50 years consumers to eat a burger without eating meat, Showcasing the latest innovations in ingredi- of Irish dairy heritage. The result is a range of drink a milkshake without drinking milk, have been ents, the New Product Zone has become some- authentic dairy and dairy-free flavours designed to impressive,” Borch said. “For the mass market thing of a trendsetting spot for the nutrition enhance dairy indulgence and build back taste. consumer however, we want to do more. Main- industry over the years. Dairy by Nature optimises flavour in a variety of stream consumers are not only looking to avoid Women’s Networking Breakfast products and can be used as primary ingredients to meat or dairy, they are looking for a great eating Join the leading women and men in the replace or mimic dairy, or to enhance the flavour experience. In order to take plant-based main- industry discuss trending topics in the industry and of existing dairy ingredients. stream, we need to expand innovation beyond break the glass ceiling. Geoff Allen, Managing Director SE Asia, imitation. We want to support the shift to a more Industry Insights Theatre Synergy Flavours (Thailand) Ltd., commented: “This plant-based diet by creating multiple options, Free presentations such as the Organic is the latest in a series of investments in Asia as we thereby enabling nutritious, plant-based food and Spotlight and Regional Market Updates offer an continue to add capacity and expertise to our overview of current global consumer trends and strategically important site near Bangkok. With the opportunities in emerging markets. new high-care blending facility, we are perfectly Supplier Solutions Sessions placed to help our customers in the region to cater The Supplier Solutions Sessions address key to emerging consumer trends, such as the interest industry trends while highlighting new ingredients in ambient or warm sports nutrition beverages and Send your news for the and technology solutions from leading suppliers. ‘growing up milk’ – for infants of 1-4 years old. Our August issue to Fi Europe co-located with Hi Europe will take global presence and combined technical and [email protected] place from 1-3 December 2020 at the Messe marketing expertise means we can help customers Frankfurt Exhibition GmBH, in Frankfurt, Germany. be quick to market with innovative, delicious Learn more on our website: products, that consumers will love.” https://www.figlobal.com/fieurope/en/home.html

12 Innovations in Food Technology | August 2020 | www.innovationsfood.com GEN NEWS:TESTING 12/8/20 16:24 Page 9

BENEO invests €60 million in increasing capacity at i South America has been the largest gathering of food and beverage Wijgmaal rice starch plant professionals in South America for over 20 years. The event provides a platform to source new food and beverage ingredients, learn about ENEO, one of the leading manufacturers France. There are expectations that other EU the latest industry developments and connect with of functional ingredients, has announced markets may follow the country in banning the leading ingredients suppliers and buyers in the a 50% production capacity increase at its additive. “We are already seeing some major region. Wijgmaal facility to cater for rising customer companies looking at rice starch and we will soon Fi South America 2020 will take place from demand for its rice starches. A two-stage expansion have a much larger capacity in place to address this 3-4 November 2020 at the Transamerica Expo process valued at €50 million, will lead to increased rising demand,” Vanhoegaerden explains. Center in São Paulo, Brazil. The event will host an capacity by March 2022. Technical trials by the BENEO-Technology expected 10,000+ expected visitors, over 500 BENEO forecasts that the growing demand for Center have shown that clean label rice starch can delegates, and 700+ exhibitors from around the natural and clean label products, in applications also play an important role in a variety of other world. Fi South America will combine with two such as coated confectionery, will intensify in major applications including baked goods and products co-located events to help visitors more easily existing markets, including Europe and the that need to undergo severe processing conditions, locate ingredients and suppliers according to their Americas. Rice is widely considered a familiar and such as sauces and dressings, as well as pet food. needs – Health ingredients (Hi) South America and recognizable product, with 61% of consumers The Wijgmaal plant has a proud 160-year Natural ingredients (Ni) South America. worldwide regarding rice starch as natural , making history in the area and BENEO has been significantly Read more about Fi South America 2020 here: it the ideal ingredient for the development of investing in the facility in recent years, to make it a https://www.figlobal.com/southamerica/en/home products that respond to the increasing trend for frontrunner in sustainability. A recent investment .html clean and clearer labels. into its docking station means that the company Show dates: 3-4 November 2020 Roland Vanhoegaerden, Operations Managing can now accept two barges at its plant, rather than Country: Brazil Director Speciality Rice Ingredients at BENEO notes one. As a result, two-thirds of rice raw material is City: São Paulo that the nature of the ingredients business is one of now received by barge and just one-third by truck. Venue: Transamerica Expo Center long-term thinking and economic resilience. “We “The impact is on cost saving, but also on the Venue address: Av. Dr. Mário Vilas Boas Rodrigues, fundamentally believe in the value of this invest- environment, due to lower carbon emissions and a 387 ment, with demand for rice starch coming from reduction in traffic. Our factory is in the middle of Opening hours: Tuesday 3 November - 13:00 - both natural and organic growth, as well as from an urban area and by increasing barge use, we can 20:00; Wednesday 4 November - 13:00 - 20:00 new projects and applications. One of the key reduce congestion and noise levels in the neigh- reasons for our confidence is the ‘clean label’ trend, bourhood,” Vanhoegaerden explains. where food manufacturers are moving away from Rice starch production consists of several artificial additives and replacing them with natural phases: rice cleaning, soaking, milling, sieving, alternatives, such as rice starch.” separation, dewatering, and finally drying. BENEO’s Rice starch is capable of filling up all of the investment at the Wijgmaal facilities will increase micropores on the surface of coatings due to its the number of production lines from two to three. very fine particle size. This so-called “smoothing The first phase of the BENEO investment will take i India & Hi is the only B2B event in the effect” is especially beneficial for confectionery place at the tail-end of the production process for Indian sub-continent dedicated to the manufacturers during the production process, since existing lines. The installation of a third drier and food and health ingredients and it ensures a stable result where edges do not crack dewatering line allows the company to reduce processing and packaging industry. Fi India & Hi or splinter. Additionally, rice starch allows for the bottlenecks and further increase efficiency. The 2020 is expected to welcome 10,000+ attendees preservation of a brilliant white colour for months. second expansion phase will involve the front-end and 230+ exhibitors. This strong growth in Since January 1, 2020, titanium dioxide, which of the production process, starting from soaking numbers reflects the ongoing growth of the food is used to fill microscopic irregularities in coatings, is through to the separation of the starch from the and beverage market in India and the surrounding no longer permitted for use in food products in proteins in the valorization step. region. The show will be co-located alongside Propak India, a dedicated platform connecting manufacturing professionals with every level of the rapidly expanding processing and packaging industry. Some of this year’s highlights at Fi India & Hi invests CHF 160 million include: Product Showcase: Discover a selection of new and innovative ingredients and vote for your to expand production favourite. The top 3 innovations will be awarded the Visitors Choice Innovation Ingredients Award. espresso recently announced a CHF 160 good in times of crisis. Nespresso confirms that Technical Seminars: Learn about latest trends million investment to expand its Romont large international groups can produce competi- and market developments in these power packed production center in Switzerland to meet tively in our region. It’s also an investment that technical sessions conducted jointly with leading increasing consumer demand for its high-quality strengthens our region in the bio-economy field Indian associations HADSA and AFSTI. premium coffees and support international devel- with which I’m very pleased," said Olivier Curty, State Discovery Tours: Discover how companies are opment in the coming years. Councillor and Director of Economic Affairs and responding to innovations in the dynamic food and "Despite the challenging times we have all been Employment at the Canton of Fribourg. beverage industry in these self-guided tours cre- living in, this strategic long term investment The construction of the second production hall ated in association with NutriMarketing. reconfirms Nespresso's continuous business success is set to start in June 2021. It will result in an Other show features include Live Demonstra- and leadership in the portioned coffee segment, augmented capacity of 10 new production lines tions and Business Matchmaking. which we pioneered back in 1986," said Guillaume Le dedicated to producing Nespresso coffees for the Fi India & Hi rotates annually between India’s Cunff, CEO of Nespresso. "It also demonstrates our Vertuo and Professional ranges and the creation of two thriving food hubs - Mumbai and New Delhi. continued commitment to our Swiss roots and to 300 new direct jobs in the next 10 years while This year’s show returns to Pragati Maidan in New the long-term economic development of the increasing third party employment and local and Delhi, India from 8-10 October 2020. region and the country, with which we share values regional business development. The first new Read more on the website: of quality, innovation and expertise." production lines are expected to be fully opera- https://www.figlobal.com/india/en/home.html "These are the kind of announcements that feel tional by June 2022.

Innovations in Food Technology | August 2020 | www.innovationsfood.com 13 INDENA:TESTING 12/8/20 16:27 Page 2

Meriva®: The Indena’s turmeric phytosome® for an effective, total wellbeing

Curcuma longa and the low-level inflammation challenge

urcuma longa L. (a member of the composed mainly of sesquiterpenes such as World Health Organization, over a third of the ginger family, Zingiberaceae) is a zingiberene, curcumol and ␣ and ␤ turmerone. 57 million deaths worldwide each year are caused perennial herb plant widespread in The three forms of “curcumin” have different by chronic diseases (cardiovascular disease, type 2 South East Asia and extensively chemical personalities and, working together or diabetes, hypertension, respiratory disease and cultivated in China, India, Indonesia individually, have been reported in literature to Alzheimer’s disease) and 90% of these diseases and Thailand. produce important effects: antioxidant, anti- have an inflammatory origin. Chronic inflammation The golden-orange rhizome from which an inflammatory, anti-mutagenic, anti-infectious, up is mainly the result of a typical western lifestyle: intense yellow ingredient is obtained is used for to an alleged anti-cancer effect. understanding its mechanisms and coping with food and for the production of supplements. As of 2019, not less than 100 human studies inflammation has become a crucial goal of modern Turmeric root has been known since ancient times have been carried out on curcumin, involving clinical research and has in fact recently been for its beneficial properties and is one of the most thousands of subjects. defined a priority by the National Institutes of widely studied botanical ingredients. In humans, the main action of curcumin is to Health in the US. The turmeric plant, and in particular its modulate healthy inflammatory response; as such, rhizome, first appeared in India as a spice, as a food it has a beneficial effect on gastrointestinal, Meriva®, follow the Life Guardian and for use in Ayurvedic medicine before 600 BC. cardiovascular, osteoarticular and hepatic health. Considering the relevance of low chronic Turmeric is part of the ginger family and, like Low chronic inflammation is the cause of many inflammation for so many people, it is important to ginger, grows easily in tropical climates. It ailments, and may also be defined today as the find a lifelong counterbalance strategy of such a probably reached China in 700 AD, West Africa silent killer of human health. According to the condition, more compatible with human body’s from 800 AD and the Americas around 1700 AD. functioning than the systematic and continuous Turmeric has many different names in use of medicines, not devoid of side different countries, but is known in many effects, especially on the medium/ languages simply as “yellow root”. This iconic long term. colour derives from three chemically An effective solution is Meriva®, distinct compounds, which are the active Indena’s turmeric formulated with components of the plant: Phytosome® delivery system, which curcumin, monodemetox- is able to help people in maintaining icurcumin and bi deme- an active lifestyle and high quality of thoxyurcumin. life. Overall, Meriva® offers lifelong All three of these support so that human curcuminoids are often body’s natural inflammatory collectively referred to as response does not turn into curcumin, both on the low-level chronic inflamma- market and also in scientific tion. literature. However, it is impor- The health support of tant to remember that each Meriva® is demonstrated by curcuminoid compound has its over 35 scientific studies in specific chemical structure and its humans, of which at least a third specific functional profile. Depending were conducted with the random- on its source and growth conditions, the ized controlled scheme. Its tolerabil- rhizome contains from 2% to 9% of ity and effectiveness in maintaining an curcuminoids and a volatile oil overall wellbeing thus keeping low-level INDENA:TESTING 12/8/20 16:27 Page 3

chronic inflammation far away, grants Meriva® the bone densities of small finger and upper jaw also in plasma of all participants when taking Meriva®. role of The Life Guardian™ as it can be taken for a significantly increased in supplemented subjects, No curcumin was detected in plasma samples of long-term life-maintenance strategy. reaching +7.1% and +4.8%, respectively, at control and placebo groups. Mean ± SD (range) Like many botanicals, turmeric has poor week 24, with respect to values at inclusion. curcumin concentration obtained was 79.7 ¬± solubility in water and is difficult to be absorbed by Noteworthy, no significant changes of heel, small 26.3 ng/ml (50.7 ng/ml to 125.5 ng/ml). the intestine, with consequent limitation of its finger and upper jaw densities were observed in As for cardiovascular health, a randomized, bioavailability. To face the challenge of a real the control group. double blind, placebo controlled study involving efficacy of curcumin, Meriva® is formulated with Eye health is another field where Meriva® «healthy» subjects with fasting plasma total Phytosome® delivery system, Indena’s proprietary support is explored, as showed in the last decade cholesterol > 5.5 mmol/L showed a synergy with technology to optimize oral bioavailability of by some human studies: phytosterols on lipids and glucose control. natural ingredients. Phytosome® is a solid • one in eye microcirculation where Meriva® dispersion of botanicals or natural products into a optimised retinal flow after 4 weeks of supple- Liver health 100% food-grade matrix based on lecithin. mentation; Two randomized, double blind, placebo Lecithins are natural surfactants which, together • one in eye membranes health: the evaluation of controlled human studies in liver function had the with bile salts, take part in the physiological process eye wellbeing during 1 year of supplementation following results: of absorption of lipophilic compounds and with Meriva® and during the follow up compared • liver enzymes amelioration (p < 0.001): -30% AST, constitute the lipid double layer of cell with the previous period of 1 year before the -25% ALT; membranes, making products, not readily soluble study enrollment, showed a prolonged period of • liver function support (ultrasonography): +24% in water, more easily absorbable for example by eye healthy function in the total number of hepatic vein flow; the intestine. subjects with relapses and in the total number of • serum lipids and uric acid reduction (p< 0.001): relapses overall; -21% total cholesterol, -17% triglycerides, -8% uric Meriva® has many fields of application, • one in meibomian gland health: supplementation acid; for an actual total wellbeing with Meriva® helped to maintain quality of life • BMI reduction (- 3%); Numerous human studies support the after 3 months, as for ocular comfort, visual • waist circumference reduction (-2%). evidence of Meriva® effectiveness in several discomfort, blurring and burning sensation As shown, Meriva® may actually be called The

conditions: joint and bone health, eyes health, control. Life Guardian™. It is a great honour that Meriva® is sports nutrition, cardiovascular health, liver health, Other human studies have been done with the only turmeric formulation endorsed by the neuropathies, gut health, skin health, healthy Meriva® in the eye health area, focusing on main- prestigious Cleveland Clinic in the USA. aging, respiratory health and prostate health. Let’s tenance of healthy vision levels, related to serum With more than 35 human studies in more go deep in some of the mentioned areas. production and macula wellbeing. than 10 different health conditions involving over 2000 subjects in more than 20 research centers, Joint and bone health Sports nutrition Meriva® is the most studied curcumin bioavailable • Three human studies in joints function had as • One study to verify the reduction of delayed formulation on the market. Human investigations primary subjective endpoints results: 58% onset muscle soreness. Results: subjective will continue to spread the health support to help decrease of WOMAC score (discomfort), >3fold (reduction of discomfort) p< 0.05 (right & left more and more people feeling better. improvement of SEI (Social and Emotional Index) anterior thighs) vs placebo; biochemical (plasma score, 26% improvement of Karnofsky Scale markers of oxidation, inflammation and lipid (function); and as primary objective endpoints state) p< 0.05 for IL-8 vs placebo; instrumental results: >4fold increase (p <0.05) of functional (MRI visualization of muscle injury) p< 0.05 score (treadmill test), 16 fold decrease (p <0.05) (posterior-medial compartment of right thigh) vs of CRP and reduction of cytokines (IL-1b, IL-6). placebo; histological (bioptic study of muscle • One human study in bone health has been held degradation); to verify the effects in healthy subjects with • one human study in endurance. Results: positive borderline bone density. The 24-week supple- effect of curcumin on IL-6 levels regulation; ment study showed that the bone density of the DALDA results indicate that participants in the heel measured by densitometer remarkably Meriva® group felt better on the day of the improved in the Meriva®-supplemented group, exercise vs placebo. Moreover, the study with a significant decrease of ultrasounds trans- independently confirmed the bioavailability of mission values at week 12 (-18.4%) and at week curcuminoids with Meriva® supplementation: 24 (-21.0%), compared with baseline values. The HPLC analysis showed the presence of curcumin www.indena.com

www.innovationsfood.com | August 2020 | Innovations in Food Technology 15 GELITA:TESTING 12/8/20 16:21 Page 2

Keep on moving: The power of collagen peptides

ith more and more people keen that nutrition plays in achieving this goal, the be ready access to targeted functional foods and to build regular physical activity market was worth USD 15.6 billion in 2019 and dietary supplements. into a holistic healthy lifestyle, predicted to grow at a compound annual growth Among all the nutrients that play a role in dietary supplementation with rate (CAGR) of 8.9 per cent between 2020 and sports nutrition, collagen is uniquely interesting. GELITA’s Bioactive Collagen 2027, according to Grand View Research. While we Naturally abundant within the human body, this Peptides® can play a key role. Scientifically proven do not know for sure how the current pandemic insoluble fibrous protein is found in large amounts to prevent injury and aid rapid recovery, they are will affect this outlook, increasing awareness of the in connective tissues such as tendons and already popular with professional athletes, who need to keep as healthy as possible, to bolster the ligaments, where it provides elasticity and tensile have seen impressive results. immune system and shed excess weight suggests strength. Right now, the global sports nutrition market that the future remains positive. Consumers are Strong and healthy tendons and ligaments are is buoyant. Driven by growing awareness of the likely to become more invested as time goes on in essential for sportspeople – both amateur and importance of living an active lifestyle and the role maintaining optimum , and key to this will professional – as they provide stability, movement,

“The specific Bioactive Collagen Peptides® TENDOFORTE® are scientifically proven to help prevent sport-related injuries and restore normal function faster.” © skynesher

16 Innovations in Food Technology | August 2020 | www.innovationsfood.com GELITA:TESTING 12/8/20 16:21 Page 3

power and speed. However, in active people in particular, injuries to these structures are common. In runners, climbers, golfers, tennis and football players, and more, injuries often result from the overuse of tendons, which bind muscle to bone, and ligaments, which bind bones together. In preventing and recovering from such injuries, rest plays a key role, but so too does effective nutrition. And this is where collagen comes in. TENDOFORTE® – Bioactive Collagen Peptides® from GELITA – can help prevent sport- related injuries and help restore normal function faster, as has already been proven by a number of scientific studies.

Strong and supportive In the human body, collagen makes up approximately 30 per cent of the overall protein content. As well as being found in tendons and ligaments, it is also present in skin, joints and bone. However, our natural ability to produce this vital protein declines rapidly with age. We may not see the visible signs of this in our tendons and “GELITA offers a whole portfolio of Bioactive Collagen Peptides®, which all act on different collagen containing parts of the body.” ligaments, but it is apparent in the loss of elastic- © Kzenon; Fotolia ity that occurs in the skin, leading to sagging and wrinkling. altitude of more than 3000 m. boost to speed the process up.” Regular intake of collagen peptides can help That is when Gavin turned to TENDOFORTE®. to boost collagen production and, in the sports 2. The long jumper “Within two months of taking a 10 g/day supple- nutrition context, it can prevent activity-induced When sports coach Ralf Weber began working ment, I noticed increased stability and strength in tendon damage. Research has shown that the with German athlete Malaika Mihambo, he noted my ankle,” he says. specific Bioactive Collagen Peptides® found in that she had been struggling with her diet Full stability was achieved several weeks earlier TENDOFORTE® stimulate the RNA expression and for some time. “I suggested working with a than doctors predicted, and Gavin says his return biosynthesis of collagen, proteoglycans and elastin nutritionist to try different forms of supplementa- to play was fast and smooth, with no lingering in Achilles tendons. For instance, an Australian tion and protein preparations,” he recalls. However, issues. “During my off-season training, I kept study found that subjects with long-term the hoped-for success was not forthcoming and supplementing with TENDOFORTE® to protect my symptoms of chronic Achilles tendinopathy were by 2016, Malaika had developed problems with the ligaments and tendons,” he says. “I wanted to test able to return to running within three months patellar tendons in both knees. Despite this, and whether I could increase my jumping performance when supplementing their diet with GELITA’s after months of conservative therapy and cross too.” TENDOFORTE®, and were able to keep running for training, she qualified for the 2016 Olympic Games, Four months later, Gavin’s trainer reported the remainder of the trial period. Further research eventually taking fourth place with a personal best that he had increased his vertical jump power and has also demonstrated that oral ingestion of the of 6.95 m. height by 28 per cent compared with the previous specific collagen peptides found in TENDOFORTE® Overcoming a foot injury so bad it could have season. “Since then, I’ve been using TENDOFORTE® improves the extension properties of finger joints. ended her career, Malaika became European as part of my daily supplement intake routine, The positive effects of TENDOFORTE® have also Champion in 2018, and coach Weber realised she making this my best season so far,” says Gavin. been endorsed by a number of professional had both the talent and the willpower to compete athletes, three of whom describe its benefits in the 2019 World Championships. “We knew, Easy to dose and take below: though, that Malaika would have to boost her At a daily dose of just 10 g, TENDOFORTE® has performance levels, dig into her reserves and focus proven to be effective for many – not just elite Professional case studies on building strength to enhance her speed,” he athletes. 1. The ultra-runner says. “And, although her muscles soon began to What is also important: TENDOFORTE® also Dr. Andrea Loew is a historian whose job takes improve, her connective tissue structures didn’t delivers very well in terms of texture, taste her to some of the most remote corners of the adapt to the workload and tended to strain and functionality in a wide variety of products, world, including Australia, Morocco, Namibia, quickly.” including bars, drinks and powders – something it Vietnam and Mongolia. And, as an extreme Recognizing that this could cost Malaika the has in common with the other Bioactive Collagen sportswoman, she can often be found exploring championship, Weber spoke to other trainers, one Peptides® in GELITA’s comprehensive portfolio. these exotic destinations in her running shoes. of whom recommended GELITA’s TENDOFORTE®. Each of these act specifically on different parts of “As an ultra-runner, I sometimes put my Within a matter of weeks of taking 10 g of these the body, and – thanks to their technological tendons and joints under a lot of strain,” she says. collagen peptides daily, Malaika’s problems advantages – they are all easy to use in multiple “And, in recent years, I’ve periodically struggled reduced significantly. “It appeared to me that the applications, including functional sports foods and with an inflamed tendon – most recently at an capacity for recovery and resilience in her training beverages as well as dietary supplements. event in the Australian outback, during which I ran had improved,” coach Weber notes. “Malaika not Alongside TENDOFORTE®, the GELITA Bioactive 522 km in nine stages.” only tolerated the intense strain of the numerous Collagen Peptides® portfolio includes FORTIGEL®, However, since supplementing with competitions during that season very well, she which is proven to stimulate joint cartilage TENDOFORTE®, Andrea says her tendons are even managed to further improve her endurance.” regeneration; FORTIBONE®, which contributes to stronger and better supported. Indeed, she had Indeed, Malaika performed in 2019 like bone health by promoting the biosynthesis of the no problems with her shins during the Ultra never before, winning the long jump World extracellular bone matrix, and BODYBALANCE®, El Djerid, a 100 km non-stop run through the Championship with a new personal best of 7.30 m. which contributes to body toning by helping to Sahara desert in Tunisia, nor at the GELITA Trail increase muscle mass and decreasing body fat at Marathon in Heidelberg. 3. The professional basketball player the same time. With targeted marketing, these “I am very grateful for the support and the Gavin Schilling is a professional basketball impressive ingredients can contribute to extremely useful advice I’ve received from GELITA, player with a German Bundesliga club. But early in innovative sports nutrition products that appeal to particularly as I have big goals for the future,” she the 2018-19 season, the 24-year-old sportsman the growing numbers of consumers with an active says. These goals include taking part in the Ultra tore three ligaments in his foot. “I quickly realized interest in this area. Norway Race, which covers 140 km and involves a that simple rehab exercises and rest weren’t going 9000 m change in altitude and the 220 km Ultra to be enough to get me back on the court in Bolivia Race, which has seven stages, all at an the time frame I wanted,” he says. “I needed a www.GELITA.com

www.innovationsfood.com | August 2020 | Innovations in Food Technology 17 VITAFOODS FEATURE:TESTING 12/8/20 17:09 Page 2

Consumer experience key to growth of plant-based meat and dairy alternatives market

Chris Lee - Managing Director, Health & Nutrition Network, Europe, at Informa Markets

s consumers continue to reduce ready-to-mix beverage product, or a food supple- consciousness, so too has the environmental and the amount of meat and dairy in ment, ingredients lists that are short and concise, sustainable credentials of ingredients and finished their diets for either health or with no E-numbers, artificial colours or additives, products entered into the plant-based food, environmental reasons, the plant- or lengthy chemical-sounding ingredients, are beverage and supplement arena. Plant-based based ingredients and substitutes much more appealing to consumers. With this products have the potential to impact the market has experienced unprecedented growth. heightened awareness around product composi- environment in similar ways to meat and dairy in In 2019, the value of the plant-based proteins tions and labelling comes increasingly discerning terms of land and water use. So now the greater sector alone amounted to US$1.6 billion, up from buying habits and behaviours; for instance, 73% of challenge for brands and manufacturers is to US$553 million in 2012.1 Despite this impressive buyers say it is important that food and drink is design plant-based products holistically, with growth trajectory, almost a quarter (23%) of global 100% natural.4 sustainability at the centre – from the raw consumers say they are concerned about the taste materials source, to the impact on the land and of plant-based food,2 while 42% admit to finding Broadening consumer values local environment, and even energy use. Not only plant-based products “bland and boring”.3 And it’s not just the ‘health halo’, or the more this, but how are the raw materials processed – are What’s more, the ‘health halo’ that tradition- proactive approach that consumers are taking to any chemicals or solvents introduced to extract the ally surrounded plant-based alternatives – where their own health and wellness that’s driving the active ingredient, or is the processing entirely buyers believed that these options are healthier demand for more natural products in the meat natural too? simply because they do not contain animal and dairy substitutes market; environmental products – is beginning to falter as consumers considerations are also crucial. Consumer values Exciting the senses become more aware of the ingredients that go are much broader, and arguably much more Sensory experience is also key to delighting into their food, and look to food labels to scrutinise exacting, than simply wanting a plant-based alter- consumers and thereby gaining long-term brand exactly what’s in the products they’re buying. In native to meat or dairy. With a more widespread loyalty. A meat or dairy substitute product may effect, they’re looking for ‘cleaner’ labels and realisation of the impact of human activity on the meet all the of the above consumer demands and greater transparency. Whether it’s a frozen, planet as well as the long-term availability of values-driven purchasing criteria, but does it taste refrigerated, or shelf-stable food, ready-to-drink or resources now entering into many consumers’ good? When buying most traditional meat and

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dairy products, consumers are looking for that moment of indulgence – savouring the joy of biting into a juicy burger, or the smooth creamy texture of a yoghurt or dairy-based pudding. It goes without saying that replicating these experiences in plant-based substitute products, particularly for consumers who identify as flexitarians, is important to maintain consumer interest and ultimately satisfaction. And all this needs to be delivered while also meeting expecta- tions for more natural, minimally processed food and beverage products.

Clean solutions One way in which some manufacturers have tried to overcome the taste challenge for meat substitute products is by adding more salt. However, this can in turn lead to the issue, and indeed headlines, about the high amounts of sodium often found in plant-based products. For example, some meat-free burgers have been found to contain on average 0.89g of salt per serving, compared with 0.75g for a traditional meat burger.5 While a quick and cost-effective consumers looking for food supplements. Here, often concerned with that moment of indulgence method of enhancing taste, adding salt to the challenges for manufacturers are similar – – only then can plant-based manufacturers really products can counter the health benefits of plant-based supplements need to be made begin to replicate these experiences fully and switching to a more plant-based diet, such as a with sustainable capsule polymers and active compete with traditional products. A new genera- reduction in fat and cholesterol that comes with ingredients, without any unnecessary or artificial tion of meat and dairy substitutes that truly deliver lowering red meat intake for example. excipients added to aid processing, and with an on taste, texture and flavour can inspire consumers Using additives is another relatively easy way eye to broader sustainability credentials such as to continue their flexitarian or vegan journeys, as to make meat and dairy substitutes taste more energy use and waste. well as encourage a whole new audience to switch authentic. Yet the continued rise in consumer to plant-based products. scrutiny over what exactly goes into their food, Help is at hand known as the clean label movement, highlights the Recent innovations are helping to drive the Where next? need for alternative, cleaner, and more natural plant-based meat and dairy substitutes market With renewed and growing consumer interest solutions to enhance both taste and texture in forward. New protein ingredient types and blends, in plant-based products, the opportunities for plant-based substitute products. While there is no such as almond or pea, can provide the high brands and manufacturers are abundant. Now, industry or regulatory definition of clean label, nutritional and ‘clean’ profile that consumers want, thanks to recent innovations in ingredient devel- consumers are clear in their desire for products while also delivering on taste and texture when opment and formulations, creating healthy, tasty that are 100% naturally formulated, with 70% compared to meat. Different types of protein can alternatives to meat and dairy, as well as more saying this is an important factor when buying also be used together to create more complex natural supplements, has never been easier. meat-substitutes.6 To meet this demand, manu- taste profiles, while in foods that allow more Indeed, with even more exciting ingredients on the facturers must therefore strike a balance between flexibility – such as vegetarian substitutes – the use horizon, the plant-based substitutes market looks the use of so-called ‘non-clean’, or overly of traditional ingredients such as eggs can help set to diversify even further, becoming not just processed ingredients, such as artificial preserva- mimic the texture of meat proteins. Supplement an alternative to meat products, but a well- tives and stabilisers, that may help to improve the formulators, too, are looking to meet increasingly established category in its own right. Who says any- organoleptic properties of plant-based foods and discerning consumer needs with the use of one has to compromise when it comes to their beverages, and formulating with cleaner, more innovative, more natural, clean label solutions – health? naturally processed ingredients that may not from the makeup of the capsule itself, to the always deliver a resoundingly positive consumer ingredients inside. References: 1 Mintel, ‘Meat Alternatives – US’, Mintel [Website], June 2013, taste experience. By considering the driving forces behind why https://store.mintel.com/meat-alternatives-us-june-2013 Clean label is now also a key consideration for consumers eat meat and dairy in the first place – 2 FMCG Gurus, ‘Top Trends PR 2020’ [website], https://fmcggurus.com/wp- content/themes/fmcg/static/img/Top-Trends-2020-Resource.pdf 3 FMCG Gurus, ‘Top Trends 2020 report’ [website] https://fmcggurus.com/ top-trends-2020/ 4 Ibid. 5 https://www.theguardian.com/food/2019/jan/27/the-trouble-with-fake-meat- beetroot-burgers-food-substitutes 6 FMCG Gurus, Top Trend: Plant life explored, 2020

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The future is NOW: Introducing Vitafoods Virtual Expo and Summit shaping profound connections in the digital age

nforma Markets announces the launch Covering personalised nutrition, digestive health of the Vitafoods Virtual Expo (7-11 and CBD, each themed half-day event will host an September 2020), the latest addition to interactive workshop, in addition to Q&As, round- its expanding portfolio of industry table and panel discussions, and speed network- trade shows and immersive online ing events. experiences. With intelligent connection and Chris Lee concludes: “The Vitafoods Virtual seamless networking at its heart, this new large- Expo and Vitafoods Virtual Summit will provide the scale interactive event aims to provide a virtual entire nutraceutical supply chain with interactive meeting place for the global nutraceutical supply online platforms to network, share knowledge and chain to build high-value relationships, showcase drive innovation in an evolving commercial land- and source innovative ingredients, discover the scape. Anticipated to run annually alongside our latest trends and together, find practical business minded peers will also be hosted via Thematic traditional in-person trade shows, these additions solutions for the greatest challenges ahead. Micro-Communities, which focus on key industry to our offering will help further facilitate dialogues, “In a world that has been turned upside down, topics including sports nutrition, botanicals, on the topics that matter the most for today and we know that what the industry needs most is healthy ageing, immune health, cognitive health, years to come, all-year-round.” connectivity”, comments Chris Lee, Managing probiotics, omega-3s, and contract manufactur- For more information on and to register for Director, Health and Nutrition Network, Europe, at ing. Each community will allow visitors to discover this year’s Vitafoods Virtual Expo and Vitafoods Informa Markets. “High-quality digital content on innovative ingredients from the industry’s top Virtual Summit, visit our website the latest consumer and market trends, science suppliers, as well as merge connectivity with a www.informamarkets.com. and regulatory developments is a driving force for unique, tailored learning experience inspired by innovation no doubt, but only alongside effective expert-led on-demand and live content, including collaboration can it help the global nutraceutical webinars, podcasts, product galleries and thematic community spearhead the future of nutrition and reports. health. This is why we’ve made it our mission to Providing a more in-depth analysis of the About Informa Markets: accelerate the digital evolution of our portfolio of nutraceutical industry, Informa Markets will also be Informa Markets creates platforms for industries and events.” launching a detailed State of the Nation report at specialist markets to trade, innovate and grow. Our portfolio is Drawing on its trusted global network of the Vitafoods Virtual Expo. It will provide insight- comprised of more than 550 international B2B events and suppliers and buyers, the Vitafoods Virtual Expo will driven commentary to inspire the industry, and brands in markets includingHealthcare & Pharmaceuticals to use data-driven matchmaking, complemented by ultimately the end consumer, while also helping to Infrastructure, Construction & Real Estate, Fashion & Apparel, a concierge service, to connect relevant visitors shape key decisions around the future of the global Hospitality, Food & Beverage, and Health & Nutrition, among and exhibitors in 1-2-1 video meetings. From the food economy and optimizing health through others. We provide customers and partners around the globe latest consumer and market trends to ground- science and innovation. with opportunities to engage, experience and do business breaking scientific insights, the event will provide Following the Vitafoods Virtual Expo 2020, through face-to-face exhibitions, specialist digital content and content that keeps the industry informed and Informa Markets will present the global Vitafoods actionable data solutions. As the world’s leadingexhibitions inspires innovation across the entire nutraceutical Virtual Summit (15-17 September 2020), which will organiser, we bring a diverse range of specialist markets to supply chain. This will be supported by regulatory give attendees the opportunity to dive deeper into life, unlockingopportunities and helpingthem to thrive guidance to help stakeholders navigate the key industry topics, as well as learn from and 365 days of the year. For more information, please visit increasingly complex route to market worldwide. network with the world’s leading nutraceutical, www.informamarkets.com. Group networking events that match like- supplement and functional food industry experts.

Visit our new NEWS website at www.innovationsfood.com

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In touch with nature

anegrade supply high-quality Pepper (Red, Green Bell) Combined with our technical expertise in fruit natural ingredients at competitive Shallot – Roasted Tamarind products, we are one of the leading suppliers of prices, and deliver them to your Tomato fruit ingredients, with particular regard both to manufacturing facility at your price and supply availability. convenience. We can recommend ingredients to match Fruit juices NFC your enquiry and we also create bespoke NFC stands for 'Not from Concentrate' so this ingredients to meet project aims such as adapting is also known as Pure Fruit Juice. mouthfeel, optimising cost or enhancing nutrition. In some applications, NFC fruit juices are Our diverse ingredients range spans many parts of preferred because they contain all the nutrients your bill of materials, meaning you can choose found in the original juice without being subject Kanegrade to focus your number of suppliers. to further processing such as concentration. Our team of food scientists are on-hand to To create NFC juices, fresh sound fruits are answer questions about shelf life, stability, particle cleaned and mechanically milled to extract the size, organic status, acidity level, extraction process, juice. This is then filtered and pasteurised before dietary consideration or any one of hundreds of Air-dried vegetable powders being filled into the packaging of choice. criteria which are relevant to our ingredients, and Air-dried powders contain only 100% A major issue with using NFC juices is their cost your finished product. vegetable and no carrier is used. in use as a high proportion of the content is water, Kanegrade holds thousands of ingredients in Their applications include: Sauces, Savoury so you are paying to ship, and store a lot of water. stock ensuring constant availability and just-in-time Biscuits, Coatings, Snack Seasonings, Dry Mixes, However understandably in some applications only delivery when required. Our network of storage Soups, Casseroles, Marinades, Gravy, Dips, Soft pure juice will do. facilities and distribution expertise mean you get Cheese, Bread, Pasta. NFC juices tend to have a higher minimum ingredients transported to your manufacturing site Asparagus Celery Parsnip order quantity, in the region of 3000Kg. They also (on the Incoterms of your choice) exactly when Beans Garlic Pea should be stored chilled at 0 - 4˚C to maintain their you specify. Beetroot Horseradish Pepper shelf life, however this will still remain short so they Broccoli Jalapeno Potato should be used as soon as possible. Cabbage – Green Leek Spinach The following NFC juices are usually available Cauliflower Onion Tomato from Kanegrade: Carrot Parsley Zucchini Apple Juice NFC Juice Pear Williams NFC Juice Apricot Juice NFC Juice Plum Juice NFC Roller-dried vegetable powder/flakes Blueberry NFC Juice Raspberry NFC juice The applications for these flakes include: Baby Blackcurrant Juice NFC Red Grape Juice NFC Food, Bread, Soup, Marinades, Coatings, Dry Mixes, Elderberry NFC Juice Sour Cherry Juice NFC Casseroles and Sauces. Lingonberry Juice NFC Sweet Pear NFC Juice Aubergine Broccoli Cabbage – Green Peach Juice NFC White Grape Juice NFC Cauliflower Carrot Celery French Beans Green Peas Leek Mushroom Onion Red Bell Pepper Vegetable products Pumpkin Spinach Sweetcorn Kanegrade is a major supplier of vegetable Tomato – Standard and Sundried ingredients to the food industry. These include: Turnip Water Cress Zucchini Vegetable Purees, Vegetable Juice Concentrates, Vegetable Powders & Vegetable Pieces

Vegetable powders Spray-dried vegetable powders Spray dried powders are on carriers, usually maltodextrin. The vast majority of the carriers we use are free from genetically modified organisms. Their applications include: Soups, Sauces, Gravy, FRUIT POWDERS Stock Cubes, Flavourings, Seasonings, Health Kanegrade is proud to produce a wide range Drinks, Flavours, Dietary supplements. of Fruit Powders. They are used in hundreds of Artichoke Asparagus applications including plant based foods, confec- Avocado Beetroot tionery, sauces, protein mixes, fillings and many Broccoli – Fresh Cabbage – Green, Fresh Fruit products more. Consumer interest in plant based products Cauliflower – Fresh Celeriac Kanegrade is a major supplier of Fruit is at an all time high with many people choosing a Cucumber – Fresh Garlic – Fresh, Fried, Roasted Products/Ingredients to industry. We retain plant based diet. The main reasons being it can be Leek – Fresh Mushroom – Fresh, Roasted strategic alliances and partnerships with fruit better for your health, it can assist in losing weight, Onion – Fresh, Roasted, Fried growers and processors around the World. it is a good diet variation, it’s good for the

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environment and it can save you money. A plant Raspberry Powder Cranberry Powder concentrated to increase the health benefit. based diet is usually made up of foods which come Banana Powder Extracts are not always possible or practical in from plants, which includes fruit powders. which case a pure material from a source high in These are fine, normally highly soluble Other fruit powders Kanegrade can offer are: the active ingredient can be supplied. powders with long shelf life, making them ideal for Acerola Powder Apricot Powder Some of the reported functional properties of use in food manufacturing. Bilberry Powder Blackcurrant Powder these plants are: Blueberry Powder Boysenberry Powder • Anti-anxiety Spray-dried fruit powders Cherry Sweet/Sour Powder Damson Powder • Antibiotic Spray-drying can be used to create a powder Date Powder Elderberry Powder • Anti-inflammatory from fruit juice. The juice is normally concentrated Fig Powder Gooseberry Powder • Antioxidant and pasteurised, mixed with a carrier to ensure Grapefruit Powder Guava Powder • Calm body & mind stable drying and then fed into the spray-dryer. Kiwi Powder Lingonberry Powder • Laxative The mixture is then pumped through a tiny nozzle Lychee Powder Mandarin Powder • Maintain healthy vision and into a heated chamber with a vortex of hot Mango Powder Melon Powder • Prevent impotence air. This causes rapid evaporation of the water in Papaya Powder Passionfruit Powder • Promote Energy the mixture, resulting in the fruit powder to be Peach Powder Pear Powder • Increase stamina collected at the outlet. Pineapple Powder Plum Powder • Enhance immune system Pomegranate Powder Quince Powder • Reduce tiredness Roller / Drum / Belt-dried fruit powders Red Grape Powder Redcurrant Powder • Assist concentration The most basic type of fruit powder. In this Strawberry Powder Tamarind Powder • Antimicrobial process fruit is passed along a set of rollers through White Grape Powder a heated chamber (Roller-Drier), tumbled in a Including functional food ingredients to your heated drum chamber (Drum-drier) or passed end product adds a compelling selling point for along a belt conveyor through a heated chamber your end consumer, or these can be used in (Belt-drier). This high-temperature process supplements or powder mixes. removes as much of the water as possible, and then the dehydrated fruits are milled/ ground/ crushed into a fine powder.

Vacuum-dried fruit powders This is a more specialist way of producing a fruit powder, which avoids exposure to high- temperature. The fruit are dried in a similar way to the roller/ belt/ drum, however as a batch process in a sealed vacuum-chamber. The vacuum lowers Functional human nutrition / Nutraceuticals the boiling point of water to around 30°C, mean- ing a lower temperature is required to evaporate Kanegrade is a leading global supplier of the water from the fruit. The resulting fruit can natural functional ingredients, also broadly known then be milled/ ground/ crushed into a powder. as 'phytonutrients' and 'nutraceuticals'. Functional This is suited to temperature-sensitive fruits, and Ingredients have health promoting, energy boost- whilst more expensive, it's less harsh on the fruit ing and/or disease preventing benefits. Inactive yeast powders preserving more flavour. Over the centuries, specific plants have been Inactive yeast powders are a good source of thought to possess functional properties to aid protein and provide a ‘meaty like’ taste to finished Freeze-dried fruit powders human health. As research into the chemicals products which are suitable for vegans. Freeze-drying is a batch process, which takes which makes up these plants has developed, the Application areas include: place in a sealed chamber. The fruit is frozen and active ingredients which stimulate those benefits • Coatings then the pressure is gradually reduced, which have been identified. Some examples of these • Gravy makes the water in the fruit jump directly from the plants are: • Marinades solid phase (ice) straight to the gas phase (vapour). • Seasonings This is a process known as 'sublimation'. The water Artichoke Extract Bearberry Extract • Soups vapour is free to leave the fruit, resulting in highly Bitter Citrus Extract Blueberry Leaf Extract • Vegetable Products dehydrated fruit with the integrity fully main- Camellia Sinensis Extract Carrot Extract • Yeast Tablets tained. As before this fruit can then be milled/ Chamomile Extract Citroflavin ground/ crushed into a powder. This is an expen- Citrolive D-xylose sive process resulting in the highest price fruit Echinacea Angustifolia Echinacea Purpurea powder but arguably most preserved. Ephedra Garlic Extract Gingko Biloba Extract Ginseng How to choose? Goldenseal Grape Seed - Red Each fruit has a particular process from each of Grape Seed - White Grape Skin Extract the above which suits it the most and is most Grapefruit Extract Green Olive Leaf Extract commonly used. This decision is based on a blend Green Tea Extract Guarana of reasons including: feasibility of manufacture, Hesperedin Hesperidin Complex cost, quality of final product required. To find out Hydroxytyrosol Kava which process from above is used for the fruit L-Arabinose Labiatae Extract powder you need, then please enquire. Milkthistle Extract Naringin Herbs & spices Note: not all fruit powders are pure fruit solids, Neohesperidin Oleuropein Herbs and Spices are the original flavours; many have carriers so consist of a proportion of Olive Leaf Extract Oreganum Extract they've been used as food flavouring for thousands fruit solids along with a proportion of carrier. The Pine Bark Rosemarinic Acid of years. These parts of plants were discovered carrier can have multiple roles including: maintain- Rosemary Extract Sage Extract early on to enhance food by imparting often ing shelf life, facilitating use in application, anti- Saw Palmetto Senna Extract complex, natural aromatic compounds to meals of caking. Carriers are processing aids and therefore Soy Isoflavones St Johns Wort proteins and other base sustenance. A little note do not have to be declared on labels (EU Law). Thyme Extract Ursolic Acid on terminology: Our range contains over 30 fruits with our Valerian Extract Yohimbe Herbs can be used fresh such as in the case of most popular being the following: mint leaves, but often herbs and spices are more Lemon Powder Lime Powder Through various methods of extraction, the concentrated in flavour, easier to store and easier Orange Powder Apple Powder amount of active ingredient from the source is to use when dried (dehydrated). The drying of

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herbs and spices is often done simply by leaving them in the sun, but they can be rapidly dried using hot air. The physical form of herbs and spices can be whole (e.g. Star Anise, Peppercorn Seed), crushed (e.g. Chilli) or ground-up as a powder (e.g. Turmeric powder).

Dried herbs Basil Bay Leaves Echemi Europe B. V. provides digital solutions on supply Bouquet Garni Chervil chain of food and nutrition, designed for customers in Chives Coriander Couch Grass Curry Leaves (XURSH :H SURYLGH EX\HUV ZLWK HIͤFLHQW RQOLQH RSWLRQV Devil's Claw Dill Products will be stored at local warehouse in the Neth- Fenugreek Garlic erlands, real-time location and stock quantity will be Ginseng Herb & Spice Mix Herbs Provencale Italian Mixed Herbs visible online. Lemon Balm Lemon Grass Lime Leaves Marjoram Mixed Herbs Mint Oregano Parsley Peppermint Rosemary Sage Tarragon Thyme

Products Stocked in the Netherlands Dried spices 5 Pepper Mix Allspice Amchur Black Pepper Caraway Seed Cardamom Cayenne Chilli Chipotle Chilli Flakes Chilli Habanero Chilli Jalapeno Chinese 5 Spice Plant Proteins Vitamins Cinnamon Cloves Coriander Cumin Fennel Fenugreek Pea Protein Isolated 80% Cyanocobalamin VB12 Galangal Garam Masala Pea Protein Isolated 85% Mecobalamin VB12 Garlic Ginger Juniper Berry Mace Rice Protein 80% VC DC 97% Mint Nutmeg Onion Paprika Rice Protein 85% Peppercorns Piri Piri Saffron Star Anise Tamarind Thai 7 Spice Turmeric White Pepper

Nutritions Sugar Reduction

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Stress relief in a probiotic snack Stress and anxiety have reached epidemic proportions. Soon the rise of probiotic mood foods may help us get our mental wellbeing back on track.

f you ask consumers what probiotic bacteria are good for, most will say digestive health. A good handful will mention immune health. But very few will name stress and anxiety relief. Over the next few years, that’s going to change. As science provides more insights into the so-called gut-brain axis, the ability of probiotics to influence our mood is a topic of growing interest – for consumers and the food industry. A DuPont-sponsored Gallup survey has shown that as many as 15% of consumers are interested in probiotics that can reduce feelings of stress and fatigue. That’s not so surprising when you consider the findings of a global survey by Regus Group, which revealed that 60% of workers regularly experience stress in their daily lives – at great expense to their long-term health and to the economy. In Europe alone, the International Labour Organization puts the estimated cost of work-related depression at €617 billion a year. “Our biological response to stress is healthy, as it dates back to our primal survival instinct. But what we’re experiencing now is more panic stress © iStock.com AntonioGuillem in daily lives and that’s causing major problems, both mental and physical,” says Dr Elaine as sleep, perceptions of stress and cognitive “More options will become available as Patterson, senior scientist and technical lead on the function.” research into suitable probiotic carriers progresses. DuPont Nutrition & Biosciences Cognitive Health Plant-based beverages have strong potential here.” Platform. From drugs to the daily diet Dietary supplement manufacturers have Where it will all begin The growth of clinical evidence already recognized the potential to offer probiotic Early adopters are likely to be countries such as Today, multiple new studies about the inter- supplements with a documented mood-support- the USA, where legislation already permits some action between gut microbes and the brain are ing effect. Among consumers, they have been structure-function claims for probiotics on published every week. Clinical studies of probiotics positively received as a welcome additional tool in product labels, suggests Eve Martinet-Bareau, for mood management are among them. Each their stress management toolbox. Global Product Manager Dupont Nutrition & one adds to the weight of evidence about specific Now it’s the food industry’s turn to develop Biosciences. China is another market with potential gut microbes with a direct influence on brain probiotic foods and beverages that can make this as consumers here simply prefer to strengthen function, both through their ability to produce feel-good sensation a regular part of the diet. their health via everyday foods rather than dietary neurotransmitters and via their influence on Based on the response to DuPont’s Gallup survey, supplements. In Japan, strong dairy brands have neurotransmitter systems. This is the gut-brain axis it seems that consumers would actually prefer to also made an impact through successful main- at work. take probiotics in a food format. stream communication of probiotic research “Classically, as scientists, we like to look at Vanessa Bailey, Global Marketing Leader at findings. biomarkers in clinical studies. So we talk about the DuPont, suggests that probiotic products in the The pace of current research suggests that it physiological effect on brain function or stress snack category will have the best market won’t be long before we see the first wave of response in terms of blood pressure, heart rate and prospects. probiotic mood foods on the market. From then cortisol levels,” Patterson says. “Nutritional bars and ready-to-drink beverages on, the sky will be the limit for manufacturers “But, if we want to know how people actually are gaining traction as convenient, functional in global markets where mental wellbeing is a feel, we also need to show a psychological snacks. Over the past few years, we’ve seen pressing consumer concern. response. This is why more studies now look at the a marked growth in launches with probiotic effect of probiotics on psychological markers, such inclusions. www.dupontnutritionandbiosciences.com

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Responsible product design: helping consumers live better through trend-driven supplement innovation

Stephane Vouche, Marketing Manager, Lonza Capsules & Health Ingredients

onsumer trends shift as social DUOCAP® UC-II® offering the convenience, ease of use and priorities evolve. Recent months Curcumin Active visual appeal consumers are looking for, without have seen unprecedented disrup- capsule compromising on the sustainable credentials that tion as people form new habits and matter so much2. Lonza’s range of Responsibly the global agenda influences how Made Products™ is built on a portfolio of hard many view health and nutrition. As food supple- capsules which are designed to support a sustain- ment manufacturers know all too well – if a new able positioning while also maximizing product product is to be a success, it is essential that efficacy. These include Vcaps® Plus capsules, a brand owners understand how to navigate premium vegan dosage form composed of just this new landscape. So what is driving our one ingredient: plant-based Hypromellose (HPMC), industry forward on a broader level and, which supports an organic product positioning in in our changing times, what do finished products in the EU when used alongside consumers want? efficacy and sustainable other organic ingredients. Vcaps® Plus capsules can credentials which are by now now also be tinted with multiple colouring foods Living better pre-requisite. Taking the wellness and such as purple carrot or red radish to create For individuals today, the mega- sustainability megatrends as a starting unique, isually appealing products that also have a trends of sustainability and health aware- point, food supplements must include clean-label positioning. ness together inform a set of values for living science-backed ingredients that consumers Plantcaps® capsules, made from a unique better and these are top of mind when they shop. associate with the health benefits they seek across formulation of pullulan, a naturally occuring Within their broader search for science-backed, a variety of market segments. It is, however, just as polysaccharide obtained by fermentation of sustainable solutions, consumers are narrowing important to choose the right delivery format – tapioca, provide an even more effective oxygen their focus to supplements that meet their current one which facilitates the high performance of the barrier than a traditional gelatin capsule. Both priorities and support achieving more specific ingredient fill while aligning with consumer HPMC and pullulan technology platforms can be goals. preferences for health- and planet-friendly used for Licaps® liquid-filled hard capsules, In our fast-paced, digital world, for instance, solutions. which offer superior, patent-protected sealing many consumers are looking for solutions to It is essential that supplement product design technology for maximum stability and DUOCAP® support better sleep and immune health, as well as does not only cover functional considerations, but capsule-in-capsule technology, which allows for to ease stress and improve cognitive performance. should also apply to a product’s look and feel. The simultaneous delivery of multiple or previously Now more than ever, a busy life does not consumer experience is imperative, and that incompatible fills, such as powders and liquids. necessarily mean physical exertion – much of our includes considerations such as swallowability, exhaustion comes from increasingly long hours taste, odour, and colour, to optimize functionality Consumer-driven innovation spent behind LED screens, working, connecting as well as on-the-shelf appeal. Dosage form choice From this springboard of responsibly made with others and e-gaming. As such, we have also also creates an opportunity to expand on a dosage forms, Lonza has developed an exciting seen a growing interest in supplement solutions product’s ethical credentials and truly stand out range of trend-led, finished Responsibly Made that help with prolonged concentration and from the crowd. Products™. These applications are designed to cognitive health, as well as for protection from blue inspire, exemplifying how brands can lever- light. There is also a growing interest in convenient Responsibly made age high-performance ingredients with supplement solutions which support beauty from Hard capsules are still the Licaps® liquid delivery dosage forms. within, empowering consumers to look good as preferred dosage form for Thanks to their high-gloss, pure they live and feel better. In the current climate, the majority of supple- and transparent appearance, Licaps® investing in looking good can provide a morale ment consumers – liquid-filled hard capsules are an ideal boost and welcome distraction from the strains of platform for beauty from within daily life. Indeed, 54% of French consumers agree products that enhance consumer appeal that grooming rituals help to reduce stress1. when combined with natural, organic and science-backed ingredients. The Licaps® formula- Capturing consumer attention tion offers a stable delivery format for trending For manufacturers, the challenge of creating ingredients, which can also be combined with on-trend supplement solutions is two-fold. First, complementary fills within a single dosage form. they must offer trend-led solutions which can Now, it is also possible to combine colouring capture consumer attention. Second, they must DUOCAP® Relax foods with the Licaps® liquid-filled technology ensure these solutions have the demonstrated capsule platform. Colouring derived from purple carrot, as

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an example, enhances visual appeal and offer benefits for eye health. It is a Licaps® Holiskin branding thanks to psychological powerful formulation, delivered in a capsule associations between purple and Licaps® Purple Carrot capsule for beauty. It can further rein- added branding and differentiation force colour attributes opportunities. What’s more, the capsule-in- capsule DUOCAP® technology platform has enabled a new generation of products that address a key priority for aging consumers: staying mobile. A single dose of just 40 mg of UC-II® undenatured type II collagen in the inner capsule, alongside highly bioavailable liquid Licaps® Digital curcumin in the outer capsule, results in What unites these Defense and Licaps® a powerful combination for joint health. aspirations is a collective Hair Plus solutions delivered Meanwhile, the cognitive health space is focus on science-backed in a Licaps® Purple Carrot capsule also a rapidly growing market. Here, vegan solutions, delivered through sustain- DUOCAP® capsules can be leveraged to deliver able methods. As Lonza’s Responsibly such as lavender for relaxation, when delivering a new combinations of ingredients to support Made Products™ demonstrate, there is no one lavender oil fill. cognitive performance and mood, alongside sleep path which manufacturers can take to meet these With self-care predicted to be an ongoing and relaxation, in a convenient, single-dose consumer needs. On the contrary: empowering consumer priority in today’s landscape, products solution. consumers to live better means providing them that can support the adjustment to a ‘new with more quality options than ever, so they can normal’ are more likely to resonate with supple- Doing better find sustainable, effective solutions for every one ment users. As their screen time has increased, For the consumer, living better is a continual of their personal health priorities. consumers may feel a need to balance intense aspiration, with no end destination – there’s always periods of concentration with switching off from room to improve, and priorities are never static. References: work, which presents opportunities for product For some, living better means sleeping better. For 1 Mintel – Industry Trend Report (France), April 2020 innovation. Enter Licaps® Digital Defense – a ready- others, living better means improving your 2 NMI SORD FR study 2018 (unpublished) to-market solution which contains a unique blend personal best during a workout. For others again, of antioxidants, carotenoids, and and lutein, which living better means looking as good as you feel. www.lonza.com

DuPont demonstrates leadership and innovation in the field of early life nutrition

DUPONT NUTRITION & BIOSCIENCES recently 2’-FL consumption by oral bacteria.” released the findings of a first-time new study Adhesion to tooth surfaces is the first require- showing the effects Care4U™ 2’-FL had on dental ment for a biofilm — dental plaque–formation, caries-associated bacterium Streptococcus mutans. 2’-FL decreased the adhesive properties of some of Previously, HMOs have not been studied for their the studied S. mutans strains. In infancy, oral effects on oral bacteria, but as HMOs are increas- microbiota develops, and delays colonization of ingly being added to infant formula, it is important potentially pathogenic bacteria is vital. DuPont is to evaluate effects on oral microflora and potential expanding on this line of research with other oral impact on oral health. bacteria and additional HMOs. “Human milk is known to contain factors that For more information on the study: DOI: protect against caries, so we were interested to https://doi.org/10.1017/S0007114520001956 October 2019, DuPont submitted a novel food know how HMOs, and especially 2’-FL, affect application with the European Food Safety Author- S. mutans, one of the most studied bacteria related Regulatory Update: Our New HMO, 3-FL ity (EFSA) to obtain market authorization in the EU to dental caries, said Johanna Hirvonen Ph.D., In addition to the exciting research being for 3-FL. These regulatory developments demon- Senior Scientist, DuPont Nutrition & Biosciences. conducted on Care4U™ 2’-FL, DuPont recognizes strate the steady progression of DuPont’s “This study was a collaboration between University the need to continue to bridge the nutritional gap investment and commitment to HMOs. of Turku, Institute of Dentistry and DuPont Nutrition in infant formula. The next most abundant HMO in & Biosciences. We evaluated the ability of S. mutans human milk after 2’-FL, and soon to be commer- Paving the path forward: new applications to grow on 2’-fucosyllactose (2’-FL) in comparison cialized by DuPont, is 3-fucosyllactose (3-FL). This As we continue to move forward with our new to galacto-oligosaccharides (GOS), lactose, and HMO is present in human milk of all mothers and is research and commercialization of novel ingredients xylitol. The effects of 2’-FL, GOS, lactose, and xylitol unique in that levels have been reported to increase in Early Life Nutrition, we need to be assured that on adhesion properties of S. mutans were also during lactation, contrary to 2’FL that decreases there is a method for the robust quantification of evaluated. While this study was done under in vitro during lactation. Initial in vitro research demon- these two compounds in the applications that they conditions, it showed the differences between the strates that in addition to being bifidogenic, this are used in. Recent published research by DuPont studied carbohydrates, especially in S. mutans HMO is effective in reducing colon motor contrac- demonstrated that a high-performance liquid growth.” tions and inhibits bacterial adhesion. Further chromatography (HPLC) method is available that “Though it is known that S. mutans can research is needed to confirm clinical benefits. allows researchers and formulators to analyze the metabolize many carbon sources, we found that A scientific expert panel has recently concluded amount of 2’-FL and 3-FL in a range of food S. mutans was unable to grow on 2’-FL, while it grew that DuPont’s newest HMO, Care4U™ 3-FL HMO, is products and quickly and efficiently perform shelf- well on GOS and lactose. Xylitol, as known before, Generally Recognized as Safe (GRAS) for use in life studies in these food applications. This is a major reduced the growth of S. mutans,” added Krista Salli, various applications including formulas intended for step forward for manufacturers interested in to M.Sc., Scientist, DuPont Nutrition & Biosciences. infants and young children, other foods and developing high quality, efficacious nutritional “Thus, the data suggests that addition of 2’-FL to beverages consumed by toddlers under 3 years as products for early life nutrition and beyond. infant formula would not support the growth of well as foods for the general population. The FDA For more information on the findings: S. mutans. The results highlight the selectivity of has been notified of DuPont’s GRAS conclusion. In https://pubmed.ncbi.nlm.nih.gov/31968133/

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Fi Europe co-located with Hi Europe will employ the highest hygiene and safety standards

his year’s Food ingredients Europe adopt and provide reassurance to attendees that at the event is our number one priority, and we co-located with Health ingredients events are being held in a safe and controlled wanted to communicate our plans as early as Europe will be organised in environment. For Fi Europe co-located with possible. We have been monitoring the situation accordance with Informa’s Hi Europe, in particular, the Informa Markets team closely, we are in daily communication with the AllSecure health and safety is in close contact and constant consultation with senior management of Messe Frankfurt with standard, developed in response to COVID-19. As the City of Frankfurt, the State of Hesse and Messe whom we are closerly observing the trade shows the world’s leading events organiser, Informa Frankfurt. already taking place in Germany and learning from Markets will employ enhanced measures to ensure Informa AllSecure is how the industry-wide those. We are very grateful for the encourage- the highest levels of hygiene and safety. Informa standard will be adopted at Informa events and ment and support we have received from all Markets is confident that the show will take place features some 35 detailed protocols, covering partners and we are looking forward to welcom- as planned from 1-3 December at Messe Frankfurt, Cleaning & Hygiene Countermeasures (prior to ing you back to the event”, commented Natasha Germany, with strong support from the Fi and Hi stand build, again before event opening and Berrow, Group Director Food at Informa Markets. Europe communities. during the duration of the event), Phyiscal Full details of the prescriptive protocols, guide- AllSecure is an industry-wide standard that has Distancing following the Crowd Density Standards lines and initiatives for Fi Europe co-located with been developed in close cooperation with as set by the State of Hesse, Communication across Hi Europe in Frankfurt will be announced over the partners, such as the Global Association of the all channels and platforms, and Protect and Detect next few months, and the organiser is continually Exhibition Industry (UFI), venues, suppliers and in collaboration with the local health authorities. exploring additional enhanced safety principles for relevant authorities for exhibition organisers to “The health and safety of everyone involved contractors, staff and exhibitors.

Recognising the best in the industry

nce again this year, during supporting pioneering ideas or innovative educa- to digestive, cognitive, immune or physical Fi Europe co-located with tional initiatives likely to positively impact the health, with a focus on natural and/or sustainable Hi Europe at the beginning of health and well-being of consumers in 5+ years’ processes December, show organizer time • Most Innovative Process, Technology or Service Informa Markets will be recogniz- • Clean Label & Natural Innovation Award for a clean Supporting F&B for innovations that improve ing companies and organizations for ground- label ingredient or process that improves sensory food safety, efficacy, quality, traceability, trans- breaking novelties in the Fi Europe Innovation and physical properties or application costs parency, ingredient sourcing, supply chain Awards. These awards are regarded as the most • Plant-based Innovation Award for a plant-based management or upcycling. prestigious in the food and beverage sector and ingredient or application that improves sensory The Challenge finalists will have the opportu- honour innovators in nine categories based on the and physical properties or application costs nity to present their particular innovation in a live latest industry trends. The Fi Global Startup • Food Tech Innovation Award for an innovative pitch to more than 1,175 exhibitors and 21,000+ Innovation Challenge gives newcomers the technical processing/ manufacturing/packag- visitors on December 1 and 2. The winners can opportunity to present their ideas to a broad ing/waste reduction solution or service for food choose between a fully-equipped exhibition stand professional audience. Entries for the Startup ingredients or finished products at Fi Europe co-located with Hi Europe 2021, a Innovation Challenge are open until 18 September, • Sustainability Innovation Award for a measurable digital promotion on the Fi Global Insights platform and, for the awards, until 25 September 2020. supply chain strategy that champions environ- for one year, access to the innovation platform A jury of industry experts, including company mental, economic or socially sustainable practices Conciergerie by Presans, a limited membership and representatives, market analysts and trade in the F&B industry fast track ticket to KitchenTown Berlin’s Accelerator journalists, will select the finalists for the Fi Europe ∑ Diversity & Inclusion Innovation Award for creat- Program, or intensive mentoring by one of the Innovation Award. Those shortlisted will pitch to ing a work environment that offers equal oppor- award partners - , as well as the life the eight-member jury led by Prof. Dr Colin Dennis, tunities for all employees irrespective of their science-based innovations (lsbi) consultancy. Chairman of the Board of Trustees of the British gender, race, religious background, sexual orien- Dr Thorsten Brandau, President of BRACE Nutrition Foundation (BNF). Colin Dennis: “Innova- tation or disabilities. GmbH, highly recommended in 2019, comments: tion in the food industry is key to future success. Preference will be given to entrants who have “The Fi Europe Innovations Awards were the Nutrition and health, along with topics such as implemented this within the last two years. perfect possibility for us to compete with other sustainability, diversity and inclusivity, are now key companies, that are the best in their field. issues for us all. The Fi Europe Innovation Awards Startup Innovation Challenge: an Receiving a High Commendation proved that we recognise the many exciting developments in all opportunity for young companies are innovative and recognized by our peers. It also of these areas. I can’t wait to see the latest novel- The awards are aimed at newcomers to the motivated us to work harder, to satisfy the needs ties in 2020, as they perfectly illustrate the rapid industry (businesses that are no more than five of the industry of tomorrow.” pace of innovation in this sector.” years old) who have a clear business plan and a Informa Markets is confident that the Fi Three of the nine categories of the Fi Europe developed concept at the very least, with proto- Europe co-located with Hi Europe will take place as Innovation Awards are new, and include the types or the final product preferred. planned from 1-3 December at Messe Frankfurt, People's Choice Innovation Award: The categories are: Germany, in accordance with Informa’s AllSecure • New: Health Innovation Award for the develop- • Most Innovative Food or Beverage Ingredient for health and safety standard. The show organizer is ment of the best ingredient or application proven ingredients or additives from an animal or plant in close contact and constant consultation with the to contribute to digestive, cognitive, immune or source that improve sensory attributes such as City of Frankfurt, the State of Hesse and Messe physical health taste, texture, smell and/or appearance Frankfurt. • New: Sensory Innovation Award for an ingredient • Most Innovative Alternative Food or Beverage For more information, please visit: https:// or process designed to enhance the sensory Ingredient for ingredients or additives from a www.figlobal.com/fieurope/en/show-high- experience of food products novel non-animal/plant source lights/innovation-awards.html and https:// • New: People’s Choice Innovation Award chosen • Most Innovative Healthy Food or Beverage www.figlobal.com/fieurope/en/show- by show attendees from all finalists Ingredient for ingredients or additives from an highlights/startup-innovation-challenge- • Future of Nutrition Award for contributing to and animal/plant/alternative source that contribute 2020.html.

28 Innovations in Food Technology | August 2020 | www.innovationsfood.com Co-located with:

Innovation at the heart of Europe: Revealing the trends of tomorrow

1-3 December 2020 Frankfurt, Germany 30 November - 2 December 2021 Paris, France

www.fi-europe.eu

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Dairy protein and its role in the health of elderly people

eniors in the 21st century are “health conscious”, in other words, they actively seek to maintain good health throughout the latter part of their life. In order to respond to this ever- growing market demand, the food industry strives to offer products with an adapted nutritional profile and texture (due to issues such as small appetite, dental problems, dysphagia, taste and smell deficiencies, …). Despite these specific nutritional needs, seniors do not want to feel categorized and so, nutritional products aimed for them must be just as indulgent, attractive and functional as its counterparts aimed for other population categories. With age, we observe changes in way of life due to decline of physical capacity and evolution of psychological state. It can drive to a decrease of physical activity and a reduction of food intake. The weight loss can be important and diseases like sarcopenia and osteopenia can appear. Protein are depending on the lifestyle.1, 2 This is the potential progressive bone weakening: this is osteopenia. It extremely important to maintain the integrity beginning of sarcopenia. The most important point is possible to simplify the evolution of bone health of muscle mass and bone mass. The growing is to provide enough proteins to the body in order degradation in 3 steps. Before the age of 50, nutritional potential of dairy protein due to their to increase the muscular protein synthesis. 1.2g of mineral density is generally normal, and bones are abundance and optimal biodisponibility in all of the proteins per kilogram of the bodyweight per day is strong. Then the first complications appear: bones essential amino acids has distinguished them as a a minimum to maintain muscular mass and start to weaken and the fracture risk increase. This first-choice ingredient for development in clinical improve physical abilities. The leucine, an essential is osteopenia. At this point, the aim is to strengthen nutrition. amino acid is also very important to trigger muscle bone mass to delay osteoporosis as much as As from the age of 40 to 50 years old, a synthesis. A quantity of leucine between 2 and 3g possible, even recover a good bone health. If reduction of muscular mass and physical abilities is necessary to stimulate correctly the anabolism nothing is done, bones will keep getting worse: begins to appear. It represents a loss from 3 to of elderly people.3, 4 this is the typical bone demineralization of osteo- 8percent of muscular mass every 10 years After the age of 50, it is common to see a porosis. 8.9 million fractures are due to osteo- porosis annually in the world. Over 200 million women are affected by osteoporosis. 1 out of 3 women over 50 years old will suffer from osteo- porosis. (International Osteoporosis Foundation, 2019) In the world, 33% of senior of 60 years and more, rate that mobility problems have a severe impact on their current health. 31% of global population are ready to take vitamins or supple- ments to treat or to help to prevent mobility problems. (Euromonitor, 2020) Bones contain proteins such as collagen and a dietary protein intake increased can helps to correctly ensure this protein turn-over and main- tain bone health. Dietary proteins could act on different mechanisms of our body and thus have a positive impact on bone health5. Proteins increases intestinal calcium absorption and muscular mass, providing a better bone protection and reducing fall and fracture risk. A 5-years cohort study completed in 2009 showed a positive link between muscular mass increase and bone health

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in elderly people.6 Calcium is the most important nutrient for building and maintaining the skeleton: 99% of the calcium of our body is in bones. Thus, to maintain a good bone health, people need a diet with proteins, vitamins and minerals (calcium, magnesium, potassium). Nutritional mimilklk proteinsproteins “Move Up”, high protein and high content calcium drink to & natural bbioactivesioactives prevent muscle and bones loss for a better mobility! At Vitafoods Europe 2020, Ingredia will be essentially focusing on nutrition and health in relation to the elderly population. We are pleased to for serenene agingaging present an innovative concept: a healthy and indulgent protein drink “Move Up” dedicated to seniors. High in protein (10% protein) and calories, this beverage with dairy ingredients is for better mobility by preventing sarcopenia and osteopenia. Packaged in a recyclable carton of 200ml, the beverage can be carried wherever you want and drink it throughout the day. “Move Up” is rich in protein (20g in 200ml, 31% of the DRI* of a senior of 65kg), a great source of CPP (CPP/calcium ratio: 1) all while maintaining a fluid, creamy texture. This beverage is naturally rich in micellar calcium (566mg, 47% of DRI* for an adult). “Move Up” is a high protein drink formulated with our dairy cooperative milk and two complementary ingredients: PRODIET® Fluid, a native micellar casein and Osteum™ CPP (Casein phosphopeptides), a milk protein hydrolysate. PRODIET® Fluid provides high content of leucine and its fast assimilation by the body, triggers muscle synthesis and thus avoiding muscle mass loss and prevent sarcopenia. The micellar caseins are slowly digested (fully digested up to 7 hours after ingestion), thus making them efficient to help maintain a normal turnover of protein in the body. PRODIET® Fluid has been specifically developed to formulate high protein beverages while retaining good fluidity (up to 14% protein). Osteum™ CPP provides a high content of CPP: 35%. CPP are phospho- rous rich peptide, known for the part they play in improving mineral absorption such as calcium. CPP acts as a carrier of calcium and improves its bioavailability and thus bone mineralization. *DRI: daily recommended intake

References: 1 Paddon-Jones D., Leidy H., 2014 2 Marzetti E., et al., 2017 3 Christos S. Katsanos et al., 2006 4 Hope Barkoukis, 2016 5 Jane E. Kerstetter et al., 2011 6 Xingqiong Meng et al., 2009

www.ingredia.com

Danone’s Open Science Research Center for Life Transforming Nutrition MUSCLES HEALTH in Shanghai

anone’s new Open Science Research Center for Life Transforming DIABETES PREVENTION Nutrition, based in Shanghai, will carry out scientific research and development work in specialized nutrition. The new center will develop evidence-based nutritional solutions tailored to the tastes, traditions and health needs of China’s consumers. To IMMUNITY BOOSTER do this, Danone will work in partnership with the public sector, medical and academic institutions, business partners and consumers in China. Research at the new center will focus on early life nutrition and nutri- tion for those with specific medical needs or the elderly – with a specific STRESS MANAGEMENT emphasis on breast milk research and gastrointestinal health. The center will also carry out projects that apply new local market, data-driven insights & digital tools to these fields of nutrition. The center will also carry out research and development projects that contribute to ongoing advances in food www.ingredia.com safety and quality in China.

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Planning for the day after: Future-proof food ingredients for thought

With the global health pandemic profoundly impacting consumer behaviour, Innova Market Insights unveil the key food trends that could be here to stay

hile it’s too early to understand canned goods. Manufacturers have the opportu- the full impact of the health nity to tap into shelf-stable ingredients like nuts pandemic on life as we know and seeds to provide the nutrition and flavour it, many of the changes to consumers are looking for, with the convenience consumer food and drink of product stability.” behaviours resulting from life under lockdown New products playing into this trend include: could be here to stay for some time. • Crazy Jack Organic’s On The Go Mixed Almonds Lu Ann Williams, Director (UK, Apr 2020). of Innovation at Innova Market • Seeberger’s Snack 2 Go Unsalted Almond Insights discusses some of Cranberry mix (GERMANY, Apr 2020). these key changes, the result- • Biscuiterie de Reims Les Coquettes Madeleines a ing trends and the products l’amande: Madeleines Made With Almond already responding: “The (FRANCE, Feb 2020). combination of not ‘physically’ going to the shops INDULGENCE: Although there is a focus on as often, a desire to stay healthy but still indulge healthy eating across Europe, consumers continue from time to time, as well as a heightened aware- to look for a release from the day to day and treats ness of the vulnerability of the planet and food and indulgences play an even larger role. safety has impacted how and what we eat. It has “With limitations placed on restaurants and also emphasised the importance of a reliable food coffee shops, there is a desire to still enjoy food, supply and healthy, shelf-stable, sustainable have some fun and recreate outside indulgent ingredients.” experiences at home. Over a quarter (28%) of This last point is key, European consumers are experimenting more with explains Dariela Roffe-Rackind, new recipes _ and people are sharing what they’ve Director Europe & Global Public and are willing to reflect that focus in their food created on social media – spreading inspiration and Relations at the Almond choices. With one-third of consumers claiming to encouragement.” Board of California, adding: be eating healthier, there’s a real opportunity for She continues: “Baking is an example here, “Ingredients like almonds can manufacturers to formulate accordingly. _” however, the increased interest has led to short- help food manufacturers innovate in step with New products playing into this trend ages of some ingredients on supermarket shelves, consumers who are thinking more profoundly now include2: like plain flour and sugar. But consumers have about what they are eating and buying – for a • Kelloggs’ Special K Immune Support Cherry, Dark been open to trying alternatives like plant-based multitude of reasons. Current trends we are seeing Chocolate and Almond Multigrain Flakes (UK, Jan or gluten-free ingredients - these provide the same require the food industry to adapt to new and 2020). pleasure when consumers can’t get what they evolving health, indulgence and responsible • Iswari Buddha Protein Amandes Grilles: Cacao need or want. These alternatives will likely grow in consumption demands to name a few. The Roasted Almond Organic Vegan Bar (ITALY, Feb popularity, particularly if supply chains fluctuate, as nutritional profile and extensive versatility of 2020). ongoing demand for access to reliable and tasty almonds, combined with their shelf-stable nature, • Les Fruits Detendus’ Granola Coco-Amande: shelf-stable ingredients continues.” means they’re perfectly placed to help manufac- Coconut Almond Granola (FRANCE, Mar 2020). New products playing into this trend include: turers do this.” BACK TO BASICS: As people learn to appreciate • Haagen Dazs’ Chocolate Choc Almond Ice Cream life’s simple pleasures, and cost a concern for (GERMANY, Apr 2020). Innova Market Insights identifies three some, consumers are turning back to basics. • Planet Organic’s Dark Chocolate Covered Almonds key trends: Williams adds: “As lifestyles have adapted to (UK, Jan 2020). RESTORING PERSONAL HEALTH: The health new restrictions, two in five European consumers • Alesto: Roasted and Caramelized Almonds with pandemic has caused consumers to think about are buying more food, drink and household Honey and Cinnamon (FRANCE, Feb 2020). the importance of keeping healthy, and the goods,[3] looking to stock up for 1-2 weeks. As well primary concern for most consumers is for their as looking at the health properties, consumers are References: 1 INNOVA COVID 19 consumer survey 2020. Country: UK, France, Germany, Spain 1 personal health and that of family and friends. considering the shelf-life of goods, with over 43% and Netherlands. % ofrespondents who are very concerned about the overall Williams comments: “Despite the rise in alter- of Europeans placing more importance here* impact COVID-19 will have on their lives. 42% ofUK consumers are most concerned for their own health and that of family and friends, 43% in DE and native therapies and trendy diets over recent years, suggesting a shift away from more indulgent 41% in FR the definition of good health is now focused on categories as well as some fresh foods. 2 INNOVA Database 2020 3 INNOVA COVID 19 consumer survey 2020. Country: UK, France, Germany, Spain conventional health, heralding a return to the “This has manifested itself in a few different and Netherlands Average ofUK, FR, Spain, Germany and Netherlands basics of good nutrition when it comes to food ways; stocking up on favourite staple items that and drink. Consumers want to nourish their gut can be stored for longer, a return to processed and look after their heart and respiratory systems foods and a new appreciation for frozen, dried and www.almonds.com

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HMOs and asthma By Janet Fricker

uman milk oligosaccharides proportion of this expenditure compromising asthma prevention should be addressed early in (HMOs) may provide the ‘missing indirect costs, such as days lost from work or life. link’ explaining the benefits school. breast feeding confers in asthma Asthma is a complex multifactorial disorder Evidence for links between breast prevention, suggest Canadian whose aetiology has been attributed to interac- feeding and asthma researchers. The effect, postulate Meghan Azad tions between genetic susceptibility, host factors The developmental origins of health and and colleagues, from the University of Manitoba, and environmental exposure, including nutrition, disease (DOHaD) hypothesis, first outlined in Winnipeg, is delivered through the ability of HMOs infection and allergic sensitization.5 While 1990 by David Barker, from the University of to boost the gut microbiome (bacteria) that in treatments are available for asthma, such as Southampton, proposed that during critical turn influences the immune system’s perinatal bronchodilators that open swollen airways and periods of early life nutritional and environmental programming of asthma. “Evidence supports the corticosteroids that reduce inflammation, there is exposure has the ability to affect adult diseases, existence of a ‘critical period’ during which the gut no long-term cure. No one would argue that rather such as obesity, hypertension, diabetes and microbiota shapes the infant immune landscape than treating asthma symptoms it would be far asthma.6 Breast feeding is a factor encountered and thus susceptibility to asthma later in life,” they better to prevent the condition from developing in early in life that has been demonstrated to relate write in a review in Frontiers in Pediatrics.1 the first place. Growing evidence suggests that to asthma susceptibility. Generally, breast feeding

Global burden of asthma Asthma, a life-long chronic inflammatory air way disease, represents one of the most common chronic health problems. It is a non-communicable disease that affects nearly 440 million people worldwide,2 and furthermore represents the leading paediatric cause of morbidity, affecting around one in seven school aged children.3,4 Asthma, a condition generally originating early in life, is characterized by recurrent attacks of breath- lessness and wheezing. During attacks, the lining of the bronchial tubes swells, causing the airways to narrow thereby reducing flow of air in and out of the lungs. While common, it should never be forgotten that asthma can be fatal. In 2016, the Global Burden Disease Collaboration estimated that 420,000 people worldwide died from asthma amounting to more than 1000 deaths per day.2 But asthma deaths represent ‘the tip of the iceberg’ with respect to the burden of this disease. In the US alone, the annual cost of asthma has been estimated at $56 billion, with a significant

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suggests, mothers who notice early signs of asthma in babies may be motivated to extend breastfeeding, thereby masking the protective effect, or even resulting in false negative associa- tions. Theories proposed to account for how breast feeding protects against asthma include breast feeding affecting epigenetic programming through DNA methylation (addition of methyl groups to DNA),14 and the physical effects of suckling resulting in increased lung capacity and airflow.15 But the prime candidate for asthma protection is the effect that breast milk has on the development of a healthy gut microbiota. Breast milk both provides the probiotic bacteria (with studies showing that it contains as many as 600 different bacterial species)16 and HMOs which are prebiotic non-digestible carbohydrates which enable selection for beneficial bacteria.

What are HMOs? Human milk oligosaccharides (HMOs) represent the third most plentiful ingredient in human milk after lactose (a different type of sugar) and fats. While more than 150 different HMOs have been identified so far,17,18 their composition follows a basic blueprint connecting five building blocks (glucose, galactose, N-acetyl glucosamine, fucose, and sialic acid) which are put together in a variety of different linkage patterns, that may be linear or branched and occur in different isomeric forms.19 Each mother produces a unique signature of HMOs, with the most extreme variations due to whether the woman is a ‘secretor’ producing the 2/FUT2 gene encoding the enzyme ␣-1,2 fucosyl- transferase that adds fucose to oligosaccharide chains in alpha-1,2-linkages. The result is such mothers have high 2’fucosyllactose (2’FU) content in milk; while mothers lacking the enzyme (known as non-secretors) have no or much lower levels. While intuitively HMOs should provide a rich energy source, the reality is that human infants do not possess the enzymes required to digest them. is considered to protect against asthma, although explanations for these conflicting findings, The result is that HMOs pass through the stomach some studies have produced conflicting results. In including different ways of describing breast and small intestine undigested, reaching the large the Canadian Healthy Infant Longitudinal Develop- feeding, such as ‘exclusive, full, predominant or intestine where they shape the intestinal micro- ment (CHILD) study, a prospective longitudinal partial breast feeding’ making it difficult to biota of babies through providing a food source cohort following nearly 3,500 families across compare results across studies. “Without informa- for just a few of the hundreds of bacterial species Canada from pregnancy through early childhood, tion on the exclusivity and duration of breast composing the intestinal microbiota, mainly investigators led by Azad, found breast feeding feeding, it is not possible to examine ‘dose effects’, Bacteroides and Bifidobacterium. Direct evidence confers protection against wheezing in the first which are helpful in assessing causality,” writes for this comes from a study showing that as the year of life.7 The protection was dose-dependent, Azad.13 Furthermore, ‘reverse causality’, where number of Bifidobacterium increases the amount with wheezing reduced by 62% with exclusive outcomes precede and cause changes in of HMOs in faeces decrease.20 Overall, the effect of breast feeding and 37% with partial breast exposure, offers another reason for inconsistency. HMOs on the gut microbiota is to stimulate growth feeding. In a second study, utilizing the same CHILD In the case of asthma and breast feeding, she of beneficial bacteria, while keeping harmful cohort, Azad and colleagues found that by three years of age, infants who had been exclusively breast fed had lower risk of developing asthma than those fed with breast milk and some expressed milk, breast milk and formula, and formula alone.8 The view of breast milk protecting against asthma is supported by a meta-analysis of 117 studies conducted between 1983 and 2012 show- ing breastfeeding to be associated with a 22% reduced risk of asthma, with the strongest effects observed during early childhood.9 However, the beneficial effect was less clear in the UK Biobank study, involving over 500,000 subjects, which showed breast feeding was protective for non- atopic asthma, but not for atopic asthma.10 Furthermore, other studies have revealed that breast feeding had no effect on asthma,11 or even that breast feeding represents a risk factor for asthma in later childhood and adulthood.12 Meghan Azad suggests a number of possible

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References: 1. Moossavi S.The Prebiotic and Probiotic Properties of Human Milk: Implications for Infant Immune Development. Front. Pediatr. https://doi.org/10.3389/fped. 2018.00197 (2018). 2. The Global Asthma Report 2018. Accessed 8.7.20 (2018). 3. Pearce N. Worldwide trends in the prevalence of asthma symptoms: Phase III of the international study of asthma and allergies in childhood (ISAAC).Thorax 758– 66 (2007). 4. Ding G. Risk and Protective Factors for the Development of Childhood Asthma. Paediatr Respir Rev 16, 133–9 (2015). 5. Dharmage S. Epidemiology of Asthma in Children and Adults. Front. Pediatr doi.org/10.3389/fped.2019.00246 (2019). 6. Barker D.J. The fetal and infant origins of adult disease. BMJ 301, 1111 (1990). 7. Azad M.B. Breastfeeding, maternal asthma and wheezing in the first year of life: A longitudinal birth cohort study. Eur Resp J doi: 10.1183/13993003.02019- 2016 (2017). 8. Klopp A. Modes of infant feeding and the risk of childhood asthma:A prospective birth cohort study. J Pediatr doi: 10.1016/j.jpeds.2017.07.012. (2017). 9. Dogaru C.M. Breastfeeding and childhood asthma: systematic review and meta- analysis. Am J Epidemiol 179, 1153–67 (2014). 10. Ek W.E. Breastfeeding and risk of asthma, hay fever and eczema. J Allergy Clin Immunol 141, 1157–9 (2018). 11. Burgess S.W. Breastfeeding does not increase the risk of asthma at 14 years. Pediatrics 117, e787–e792 (2006). 12. Sears M.R. Long-term relation between breast-feeding and development of atopy and asthma in children and young adults: a longitudinal study. Lancet 360, 901–7 (2002). 13. Miliku K. Breastfeeding and the Developmental Origins of Asthma: Current Evi- dence, Possible Mechanisms, and Future Research Priorities. Nutirients doi:10.3390/nu10080995 (2018). 14. Hartwig F.P. Breastfeeding effects on DNA methylation in the offspring. A sys- tematic literature review. PLoS One 12, e0173070 (2017). 15. Ogbuana I.U. Effect of breastfeeding duration on lung function at age 10 years: A prospective birth cohort study. Thorax 64, 62–66 (2009). bacteria in check.19 University of California, San Diego, La Jolla, and the 16. Fujimura K.E. Neonatal gut microbiota associates with childhood multisensitized Additionally, HMOs may indirectly influence infants given skin prick tests at one year of age to atopy and T cell differentiation. Nat Med 1181–1191 (2016). 17. Wu S. Development of an annotated library of neutral human milk oligosaccha- composition of the gut microbiota through ‘decoy check for sensitization to common allergens, rides. J Proteome Res. 9, 4138–51 (2010). ‘activity, where they have structural homology to including certain foods. Results showed that 59 of 18.Wu S. Annotation and structural analysis of sialylated human milk oligosaccha- rides. J Proteome Res. 10, 856–68 (2011). cell surface glycans, preventing bacteria from the infants (14 % ) displayed sensitization to one or 19.Bode L. Human milk oligosaccharides: every baby needs a sugar mama. Glyco- binding to the intestinal epithelium.21 It is also more food allergens, and that while no individual biology. 22, 1147–62 (2012). possible that HMOs could have a direct effect on HMO was associated with food sensitization, the 20.Matsuki T.A key genetic factor for fucosyllactose utilization affects infant gut mi- crobiota development. Nat. Commun. 7, Article number: 11939 (2016). the lungs since approximately 1 percent of HMOs overall profile of HMOs appeared to play a role.30 21.Morrow A. Human-milk glycans that inhibit pathogen binding protect breast- are absorbed into the peripheral circulation, open- "Our research has identified a 'beneficial' HMO feeding infants against infectious diarrhea. J Nutr 135, 1304–7 (2005). 22.Bode L. The functional biology of human milk oligosaccharides. Early Hum Dev ing the way for HMOs to influence infant microbial profile that was associated with a lower rate of 91, 619–22 (2015). communities at body sites other than the gut, food sensitization in children at one year," said 23.Strachan D.P. Hay fever, hygiene, and household size. BMJ 299, 1259–1260 22 (1989). including airways and the nasopharyngeal cavity. Bode in a press release published at the time. "To 24.Abrahamsson TR. Low Gut Microbiota Diversity in Early Infancy Precedes Asthma our knowledge, this is the largest study to examine at School Age. Clin Exp Allergy 44, 842–50 (2014). Role of the gut microbiota in the association of HMOs and allergy development 25.Arrieta M.C.The intestinal microbiome in early life: health and disease. Front Im- munol /doi.org/10.3389/fimmu.2014.00427 (2014). development of asthma in infants, and the first to evaluate overall HMO 26.Gollwitzer E.S. Impact of Early-Life Exposures on Immune Maturation and Sus- Evidence is growing that gut microbiota profiles." ceptibility to Disease. Trends Immunol 36, 684–96 (2015). 27.Azad M.B. Perinatal Programming of Childhood Asthma. J. Immunol. Res. provide the connection between different HMO Next, Azad and Bode plan to use Bode’s doi.org/10.1155/2012/932072 (2012). profiles, and development of the immune system analytical platform to undertake prospective 28.Li M. Early development of the gut microbiome and immune-mediated child- hood disorders. Semin Reprod Med. 32, 74–86 (2014). regulating protection against allergies, including studies exploring asthma diagnoses and infant 29.Kaplan J.L. The role of microbes in developmental immunologic programming. asthma. feeding exposures including the influence of Pediatr Res 69, 465–72 (2011). In 1989, David Strachan proposed the ‘hygiene different HMO compositions of milk on the 30.Miliku K. Human milk oligosaccharide profiles and food sensitisation among in- fants in the CHILD Study. Allergy 73, 2070–73 (2018). hypothesis’, exploring how lack of microbial subsequent development of asthma. exposure during childhood results in perturbations Ultimately, if studies can identify the HMO in gut microbiota and aberrant immune responses profile protecting against asthma, this opens the to innocuous antigens later in life, causing condi- way to prevent asthma from developing in the first tions such as asthma.23 One study showed that place. But until recently, benefits of HMOs were children who develop asthma have lower total gut limited to breastfed babies because it was not microbiota diversity than children who do not possible to source HMOs elsewhere for inclusion in develop asthma at both one week and one month formula milk. However, the German company of age.24 Jennewein Biotechnologies GmbH has developed At birth, the immune system is dominated by a unique HMO production process based on the T-helper cell type 2 (Th2) which as the child bacterial fermentation, allowing industrial- develops shifts to the Th1 and Th 17 pheno- scale synthesis of a range of HMOs, including types.25,26 In early infancy delays to this transition 2‘-Fucosyllactose, 3-Fucosyllactose, 3‘-Sialyllactose, (Th2 to Th1) have been associated with increased 6‘-Sialyllactose, Lacto-N-tetraose, Lacto-N- risk of developing atopic disorders, including neotetraose and Lacto-N-triose II. Such industrial asthma.27 In separate studies it has been demon- production of HMOs offers opportunities to strated that the microbiota stimulates regulatory manufacture protective HMOs in large quantities T cells that help monitor the Th1/ Th2 balance.28 ,29 and add them to formula. Additionally, since Contact details “Thus, early life microbiota disruption could lead to mothers produce unique profiles of HMOs this alterations in several immune parameters including creates the possibility to test their milk to see regulatory T cells proliferation, Th17 response all of whether it contains the protective profile, and if which contribute to asthma development,” writes not supplement their milk with the missing HMOs. Azad.1 In future, such innovations offer the possiblity to make asthma prevention a reality. Evidence for link between HMOs and asthma To date, the strongest evidence for links Dr. Bettina Gutiérrez between HMO composition in human milk and Jennewein Biotechnologie allergy comes from research undertaken using the Tel:+49 02224/98810797 CHILD cohort. Here, breast milk samples taken from Email: 421 mothers three to four months after birth were [email protected] analysed for HMO content by Lars Bode, from the www.jennewein-biotech.de

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Emsland Group offers new waxy potato starch solution

MWAXY® is based on high amylo- formulations. Being specialized in the production, Innovation from soil up! pectin potatoes, containing more application and supply of vegetable ingredients, The cultivation of this new potato variety is a than 99% amylopectin, resulting in the Emsland Group is able to promote constant clear sign that raw material manufacturers still have high quality end products. This growth and demand for healthy and genuine the ability to truly innovate in the market place. natural potato variety is being ingredients. In close cooperation with their part- With the introduction of EMWAXY® potato starch, cultivated through traditional, non-GMO breed- ners, the Emsland Group has now developed high the Emsland Group presents a waxy potato starch, ing techniques. EMWAXY® is a new commercial amylopectin potatoes EMWAXY® product range. which has an amylopectin content of more than available amylopectin potato starch giving By means of contract farming, the Emwaxy 99%. improved performance to final products at our potatoes are exclusively grown for the Emsland Heidrun Lambers, Head of Food Application customers. Group. Therefor the potato meets all the quality Technology at the Emsland Group explains Emsland Group is founded in 1928 and leads requirements of the company. Within the Emsland “EMWAXY® can provide high transparency, new the market with potato and pea based solutions. Group, all products manufactured at all sites are textures, high viscosity, physical shelf life extension The company produces high quality starches, flakes plant based, non GMO, Kosher and Halal. as well as smooth and glossy appealing products”. and granules, special derivatives, proteins and The EMWAXY® range fits seamlessly with the In food applications the use of EMWAXY® has fibers for the use in a wide variety of food current product portfolio of the Emsland Group. next features: • High viscosity • Clarity, smooth and glossy appearance • Clean flavour and bland taste • Excellent creamy mouthfeel • New textures, resulting high expanded crispy snack products • Optimized process possibilities. Lower gelatiniza- tion temperature, fast hydration, quicker cooking times and lower energy input in comparison with other starches can be the result. EMWAXY® is high valuable with a lot of benefits in food applications and offers a good start to create new innovative appealing products. These unique material characteristics of EMWAXY® serves todays trends e.g. easy handling, natural, lower dosage possibilities, non-GMO, kosher & halal, gluten and allergen free as well as clean label opportunities. Emsland Group experts can assist you selecting the right product for your application. Please contact the Emsland group at: [email protected]

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ACACIA GUM, A VERSATILE INGREDIENT FOR SUGAR-FREE FOOD AND DRINKS!

Acacia gum has a role to play in the formulation of sugar-reduced or sugar-free products. As ƒ ϐ‹„‡”ǡ ‹– ƒ Š‡Ž’ ™‹–Š –Š‡ ‰Ž› ‡‹ ”‡•’‘•‡ ‘ˆ ˆ‘‘† ƒ† †”‹•ǡ „—– ƒŽ•‘ ƒ –• ƒ• ƒ ƒ‰‡– ‘ˆ –‡š–—”‡ǡ „”‹‰• ˜‘Ž—‡ǡ •–ƒ„‹Ž‹–› ƒ† ‘—–Šˆ‡‡ŽǤ • —• ‘”‡ ‹ˆ‘”ƒ–‹‘ ƒ–ǣ ƒŽŽƒ†”‘„‡”–Ǥ ‘Ȁ•—‰ƒ”Ǧ”‡†— –‹‘ ŽŽƒ† Ƭ ‘„‡”– Šƒ• „‡‡ ƒ—ˆƒ –—”‹‰  ƒ ‹ƒ ‰— •‹ ‡ ͳͺͺͶǤ ‹–Š ‹–‡‰”ƒ–‡† •—’’Ž› Šƒ‹ǡ —•–‘‹œ‡† Ƭ ƒ† –ƒ‹Ž‘” ƒ†‡ —•–‘‡” •‡”˜‹ ‡ǡ ™‡ Šƒ˜‡ –Š‡ ‡š’‡”–‹•‡Ǩ ROUSSELOT:TESTING 12/8/20 17:07 Page 2

Is collagen the way forward for the joint health market?

s health and fitness trends soar, Globally, the joint and bone health ingredients over 20% of the world’s population will be over 60 more consumers are recognizing market is projected to hit US$ 3.3 billion before years old by 2050. That’s around two billion people the importance of looking after 2024, with a compound annual growth rate (CAGR) – a doubling since 2015. In the older age bracket, their joints. As new consumer of 6.4%.1 Within the broader supplement market, WHO predicts there will be 434 million people aged groups with distinct wants and it is quickly becoming a significant segment: the 80 or older globally, a substantial increase from 125 needs emerge, choosing the right ingredient is vital number of supplements launched with a joint or million in 2015.3 for success in this growing market. In this article, bone health claim rose by 7% globally between This demographic shift brings new challenges Rousselot Health & Nutrition, outlines the value of 2014 and 2018.2 and opportunities. As people age, the strain on collagen as a joint health supplement. Two worldwide trends are pushing joint health their joints and bones increases: with cartilage to the forefront of the health and fitness market, thinning and the amount of lubricating fluid What is driving growth in the joint contributing to its rapid growth: decreasing, joints become stiff and less flexible. health market? 1. A population shift The resulting stiffness makes exercise more The joint health market is growing quickly, with The numbers are clear: the population is aging. difficult, while the risk of injury also increases. no indications that it will slow down anytime soon. According to the World Health Organization (WHO), An aging population also means a higher ROUSSELOT:TESTING 12/8/20 17:07 Page 3

number of people struggling with joint issues. Currently, an estimated 1.7 billion people are affected by arthritis globally.4 With the impact of aging being felt by more across the world, joint health supplements will play a key role in support- ing consumers in their efforts to stay active as they age. 2. The rise of sports nutrition and the active consumer With each passing year, the concepts of health, fitness, and well-being are becoming more prominent. As the general public’s awareness of staying active is growing, the sports supplement market is moving away from the niche base of elite sportspeople. Now, casual consumers are working on their fitness routines, whether to maintain their health, develop new skills, or compensate for their increasingly sedentary lifestyles. The market shows this rise, with Euromonitor predicting a 10.6% CAGR for the sports nutrition market between 2018 and 2023.5 For the consumers who are taking charge of their fitness, keeping their joints strong and healthy is of the utmost importance. quality of their lives. relates to cartilage. Cartilage is pivotal for joint Which consumer groups are using joint 21st-century demands health: tough but flexible, it acts as a cushion and health supplements and what do With joint health supplementation moving shock absorber to bones and joints. Collagen plays they want? beyond the world of elite athletes into the main- a key role in maintaining it, with collagen fibers In the joint health and sports nutrition market, stream, consumers want new formulation options making up 70-95% of cartilage. professional sportspeople have been the key in addition to bars, powders, and drinks. Some are Overall, then, collagen is responsible for the consumers for many years, using supplements as looking for indulgent options, like chocolate-in- structure and strength of the joints. These means a means to support their athletic regimes. fused bars, while others may prefer a ready to drink it is essential to movement, agility, flexibility, and However, recent global trends are creating new mobility. As we age, the body’s ability to replenish consumer bases looking to prevent injury and collagen decreases. This explains why collagen maximize their active years in different ways. supplementation is valued so highly. Healthy agers Collagen peptides Aging is no longer perceived the way it used to By turning natural collagen into collagen be. Today’s older consumers are breaking down peptides, we can create ingredients with health the traditional perception of aging as ‘a process of and sports nutrition benefits. In this process, slowing down’. Instead, these healthy agers are known as enzymatic hydrolysis, short chains of looking to stay active as they age, whether by amino acids, also called collagen peptides, are picking up new hobbies and skills or maintaining extracted from native collagen. This collagen can their current routines. be derived from animal source. By using a specific These healthy agers want to sustain the health enzyme to break down the bonds, collagen of their joints, making sure they can stay active as (RTD) solution. peptides are released from the tough and they age while preventing any new issues arising Similarly, these new consumers are looking for insoluble matrix of collagen fibers. Collagen that could negatively impact their routines. They more than a niche product: they want holistic peptides are soluble in cold water and are easily are looking for supplements that can help them solutions with multiple benefits. Think, for digested and absorbed by the human body, stay mobile, flexible, and active for as long as pos- example, of a joint health supplement accompa- entering into the bloodstream and influencing the sible: almost a quarter of US supplement users over nied by a broader diet and exercise plan. activity of the targeted cells. 55 cite joint health as their top reason for using The third characteristic of today’s consumers supplements.6 These consumers are looking for is their environmental consciousness. Looking Collagen peptides and joint health new solutions available in mainstream channels, beyond individual products, they care about the Collagen and collagen peptides are widely alongside new application formats such as bever- safety and sustainability of solutions, natural used as health supplements. Two examples of joint ages. origins, and the trustworthiness of the companies health solutions are hydrolyzed collagen type I and Casual sportspeople behind them. type II. A new, more casual group of sports nutrition With such a broad range of consumer desires, Hydrolyzed Collagen Type II matrix supplement users is emerging. Following the the active ingredients used in joint health supple- Type II collagen is a type of protein found in example of elite athletes and hard-core body- ments today need to be efficient, safe and the tissue of cartilage, being one of the main builders, more and more active consumers today natural, versatile, and suitable for many application collagenous substances there. Part of the tightly are using supplements to support their bodies as options. With these properties in mind, many packed matrix of fibrils and fibers, type II collagen they exercise. These casual sportspeople have a leading nutraceutical manufacturers opt for gives cartilage its tensile strength and elasticity. It wide range of demands, from maximizing collagen as an ideal ingredient. plays a vital role in the function of the joint, performance levels and recovery times to helping to connect bones to each other and preventing injury and repairing any ongoing issues What is collagen? allowing the tissue to bear mechanical stress. they may have. Collagen and its role in the body Supplementation with type II collagen For casual sportspeople, the condition of their Collagen is the most abundant protein in our peptides can support healthy joints. Peptan IIm, for joints is a vital part of their lifestyles: it allows them bodies and the most important structural element example, is a product specifically designed for joint to stay mobile and flexible. The number of of our connective tissues, making up around 30% health. Peptan IIm comes from cartilage and consumers using joint health supplementation for of the total protein content. It plays a key role in represents a natural matrix of hydrolyzed collagen this reason is steadily rising, with almost 50% of providing strength, flexibility, and elasticity to our type II and glycosaminoglycans (GAGs). It offers global supplement users doing so in response to skin, cartilage, ligaments, and bones, acting as the three key joint health benefits: joint and bone health concerns.7 From younger glue that connects everything in the body. • Promotes healthy cartilage and joint function; people looking to prevent musculoskeletal injury Collagen is built with a strong triple helix structure, • Supports healthy cartilage and connective tissue; to middle-aged consumers eager to remain with three amino acid chains that form stable • Helps protect cartilage and ease occasional joint mobile, consumers of all ages are embracing fibers. stress.8 joint health supplementation to maximize the Another important role of collagen in the body These benefits have been demonstrated in

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reliable research. One in vivo study showed that Peptan IIm stimulates chondrocytes to produce the lubricating matrix at a low dosage, as well as being absorbed quickly and easily.9 Effectiveness at a low dosage is vital, as it offers consumers maximum convenience. Altogether, the benefits of Peptan IIm make it a strong ingredient for joint health supplements. Peptan IIm is valued by manufacturers for being safe, and highly soluble, as well as for offering exceptional application versatility: it can be integrated into a wide range of solutions, from drinks and powders to bars and gummies. Type 1 collagen peptides Collagen peptides are used in supplements for joint and bone health, sports nutrition, beauty, and healthy aging, as they offer a broad range of health benefits. Peptan, the world’s leading collagen peptide brand, has investigated the health benefits of its ingredients with independent research institutes. The resulting studies have shown Peptan’s unique ability to: • Support joint health;9,10 • Support bone health; 11,12,13,14,15 Collagen’s bioavailability site of action refers to the targeted tissue, such as • Reduce muscle soreness and recovery time The level of bioavailability of functional bone, joint or skin. The high bioavailability of pure post-exercise;16 ingredients, such as collagen peptides, is a crucial collagen peptides is a prerequisite to deliver a • Promote beauty from within.17,18 contributing factor — amongst others — to their reasonable fraction of small bioactive peptides to These science-backed benefits make Peptan efficacy. In order to be effective and provide the targeted tissue and to guarantee the biologi- an ideal solution for consumers looking for holistic benefits to consumers, ingredients must be cal efficacy of the ingredient. This also means that and versatile joint health supplements, from bioavailable to an extent that allows them to be collagen peptides are suitable for a wide range of weekend warriors eager to intensify their training efficiently digested, absorbed and delivered to the application forms. schedule to healthy agers. site of action. In terms of collagen peptides, the A new in vivo study has highlighted the

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References: 19 bioavailability of Peptan collagen peptides. The collagen, must also be traceable. Consumers want 1 Mordor Intelligence appearance of free and peptide-bound hydrox- assurance that the ingredients they use are 2 Innova Market Insights 3 World Health Organization, Aging and Health yproline was measured in the blood of subjects 24 harmless and part of a chain of accountability. 4 World Health Organization hours after their ingestion of Peptan. Peptan was  Natural origins, sustainability 5 Euromonitor, 2018 quickly absorbed by the body. Analysis of serum Clean label ingredients of natural origin that 6 CRN, Consumer Survey on Dietary Supplements, 2018 7 Ipsos, Health and Nutrition Survey, 2019 (USA, Spain, Brazil, France, UK, Japan - drawn from the subjects showed that Peptan are sustainable are also important: more and more N=2300) intake led to an increased intake in hydroxyproline- consumers in this market will only include a 8 Soniwala, S. et al. 2018. Oral hydrolyzed type 2 collagen protects against the OA of obesity and mitigates obese gut microbiome dysbiosis. Osteoarthritis and 20 carrying dipeptides, known in scientific literature supplement in their routines if it meets these Cartilage, doi: 10.1016/j.joca.2018.02.377 as markers for collagen bioactivity – described as requirements. 9 Jiang J.X. et al., 2014, Collagen peptides improve knee osteoarthritis in elderly women: A 6-month randomized, double-blind, placebo-controlled study. Agro ‘carrying bioactivity’. These FOOD Industry Hi Tech, 25:19-23 findings show collagen  Application variety 10 Dar, Q. et al., 2017. Daily oral consumption of hydrolyzed type 1 collagen is peptides’ efficacy when Beyond the ingredient itself, modern chondroprotective and anti-inflammatory in murine posttraumatic osteoarthritis. PLoS ONE 12(4):e0174705 ingested. consumers are looking for a wide range of appli- 11 Guillerminet, F.et al., 2010, Hydrolyzed collagen improves bone metabolism and To learn more, watch cation formats. Some want tasty products in a biomechanical parameters in ovariectomized mice:An in vitro and in vivo study. Bone, 46:827-834 the Peptan collagen peptides range of flavors while others prefer diet-compliant 12 Guillerminet, F. et al., 2012, Hydrolyzed collagen improves bone status and video https://youtube/ options. Consumers are now looking for these prevents bone loss in ovariectomized C3H/HeN mice. Osteoporosis International, 23(7):1909-1919 ou1hvH_wuwY products in mainstream channels and expecting 13 Daneault, A. et al., 2014, Hydrolyzed collagen contributes to osteoblast them to be tailored to their own needs. differentiation in vitro and subsequent bone health in vivo. Osteoarthritis and What are consumers looking for in their Cartilage, 22:S131 14 Daneault, A. et al., 2017, Biological effect of hydrolyzed collagen on bone joint health supplements? How is Rousselot collagen answering metabolism. Critical Reviews in Food Science and Nutrition, 57(9):1922-1937 Today’s consumers require solutions that can today’s consumer demands? 15 Wauquier F.et al., 2019, Human enriched serum following hydrolysed collagen absorption modulates bone cell activity: from bedside to bench and vice versa, meet their wide-ranging needs and values. Here Collagen is recognized by more brands and Nutrients, 2019, vol. 11, no. 6, pg. 1249. are four key qualities that matter: manufacturers as a perfect ingredient for the 16 Clifford, T, et al., 2019. The effects of collagen peptides on muscle damage, inflammation and bone turnover following exercise: a randomized, controlled growing joint health marketplace. Able to help trial. Amino Acids 51(4):691-704, doi.org/10.1007/s00726-019-02706-5  Trustworthiness maintain healthy joints, Rousselot collagens are 17 Rousselot unpublished study It is fundamental that consumers can trust what is suitable for the growing number of healthy agers 18 Asserin, J. et al., 2015. The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo on offer. This is why they tend to prefer branded and active sportspeople. Alongside its joint health model and randomized, placebo-controlled clinical trials. Journal of Cosmetic ingredients from reputable manufacturers with benefits, Rousselot collagen offers other unique Dermatology, doi: 10.1111/jocd.12174 19 Kleinnijenhuis, A.J., 2019. Non-targeted and targeted analysis of collagen scientific evidence to back-up their claims. traits: they are a safe, clean label ingredient of hydrolysates during the course of digestion and absorption.Anal Bioanal Chem. Solutions that are not backed by science and natural origin offering application versatility and 2019 Dec 24. doi: 10.1007/s00216-019-02323-x. 20 Ichikawa, S. et al., 2010, Hydroxyproline-containing dipeptides and tripeptides presented by trustworthy players are easily passed high bioavailability. quantified at high concentration in human blood after oral administration of by. Manufacturers wishing to highlight specific The growing popularity of collagen is a good gelatine hydrolysate. International Journal of Food Sciences and Nutrition, 61 product benefits in their advertising or labelling indicator of its perceived efficacy in joint health: (1):52-60 21 SPINS, Michelle Gillespie, 2019 must also operate within the legal framework of between 2018 and 2019, sales of collagen-based existing worldwide regulations concerning health supplements across all markets rose almost 80% to claims. US$ 116.2 million.21 All in all, collagen offers just what 21st-century  Safety, traceability consumers are looking for on the joint health More than ever, ingredients must be safe and market. For manufacturers, it opens a clear path compliant with key certification schemes and toward thriving in this exciting growth market. regulations regarding feed, welfare, and overall To find out more about the benefits of (food) safety. Products of natural origin, such as collagen peptides, visit Rousselot.com/health. www.rousselot.com/health

Nestlé to expand affordable nutrition portfolio in Southeast Africa

ccess to affordable nutrition is challeng- Center in Abidjan. ing for many consumers worldwide. The porridge was developed with high-quality, Nestlé is accelerating its efforts to locally and sustainably sourced ingredients, while develop more affordable nutritious products for leveraging existing roller drying and dry-mixing consumers, particularly those in emerging technologies. Nestlé packaging experts also worked countries. This enables the company to improve its alongside local suppliers to develop an affordable, product offerings for lower-income families, many recyclable laminate packaging, which protects the of whom live on a few dollars a day, often resulting product throughout the shelf-life. in a lack of essential nutrients in their daily diet. The porridge was first launched in July in One example is the recent launch of Nestlé Zimbabwe in a limited number of stores, with a Cerevita Instant Sour Porridge, an affordable nationwide launch and rollout in more countries nutritious solution for Southeast African consumers. planned for later this year. It is made with wholegrain cereals and fortified with Nestlé's R&D Center in Abidjan, Côte d'Ivoire is key micronutrients, which are typically lacking in adapted to local consumer taste preferences part of the global Nestlé R&D network, which local consumer diets. The porridge has a higher and nutritional requirements while minimizing consists of 23 locations worldwide. The center has fiber and protein content and costs about 20-25% production costs to ensure affordability. food technologists, scientists, and engineers who less than the similar products available in local "The current COVID-19 crisis around the world primarily specialize in the innovation of cereal, dairy, markets. will lead to a further lack of affordable nutritious snack, and beverage solutions. It also collaborates The porridge was developed and launched in foods for many vulnerable consumers. We are with local universities and innovation partners. Last about one year by scientists at Nestlé's R&D Center increasing our efforts to address affordability by year, Nestlé launched an R&D innovation challenge in Abidjan, Côte d'Ivoire, in collaboration with cross- rapidly developing, testing, and launching safe, in sub-Saharan Africa, which saw three start-ups functional teams from Southeast African markets. high-quality, affordable, nutritious products that embark on a 4-month residency in the Nestlé R&D The R&D center leveraged its science and technol- meet the needs of sub-Saharan African consumers," Accelerator for sub-Saharan Africa, located at the ogy capabilities to develop a porridge that is says Tesfalidet Haile, Head of Nestlé's R&D R&D Center in Abidjan.

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Demand for organic ingredients surges in the wake of coronavirus pandemic

he coronavirus pandemic has led well as clean and clearer labels. In fact, one in three easy to understand why. to a surge in demand for more consumers around the globe say that they have sustainable and organic foods. increased their research on ingredients over the The rise of organic Now, more than ever before, past year2 and 63% of UK consumers agree With organic products and ingredients consumers want to make ethical that brands should be more transparent about considered a vital element for ethical and sustain- and healthier choices and with one in two the content of their products3, leading to a able purchasing behaviour, consumer interest in all consumers looking at the ingredients list on rise in demand for products that respond to this things natural continues to grow. Figures show products before buying1, what goes into our food trend. In the UK for example, Mintel predicts that organic products have become more important to and drink has never been so important. Here, ethical food sales will rise by 17% to £9.6 billion 1 in 4 consumers in the last year5 and many are Thomas Schmidt, Marketing Director at BENEO, between 2019 and 2023, and with 29% of willing to pay a premium price for them6, thanks discusses the rising consumer interest in label European consumers looking for some kind of to the growing consumer perception of these transparency and how this is driving demand for traceability label on their products before products as healthy and natural, and therefore an organic functional ingredients. purchasing (e.g. organic, vegan, fairtrade)4, it’s intrinsic part of a healthier lifestyle. Even before the coronavirus pandemic hit the headlines and impacted markets around the world, the important issue of well-being had been brought to the fore and highlighted as a major trend for 2020 and beyond. According to Mintel’s Director of Innovation and Insight, David Jago, “well-being is no longer about simply wanting to look after oneself in broad terms, nor is it about the extremes of a total lifestyle change or com- mitment to an intense regime. Instead, a holistic, longer-term approach is becoming a key motivator of consumer behaviour, underpinned by conven- ience, transparency and value. Concern for our environment will also grow and successful compa- nies will be those that improve the health of the planet and its population.”

Transparency is key Consumers want to know and understand more about what is in their food and drink products, so that they can consciously make ethical and healthy buying decisions. Transparency is a powerful purchasing driver for consumers, with many actively seeking out products that promote sustainability, organic and natural ingredients, as

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The coronaviruseffect According to Soil Association Certification, the UK’s organic market is set to surpass the £2.5bn sales mark by the end of the year – achieving more than 50% growth in a decade7. However, in light of the recent Covid-19 pandemic, it is highly likely this trend will be accelerated even further as a result of the increased consumer understanding of, and interest in, the link between nutrition and health. Organic foods have, not surprisingly, benefit- ted from heightened interest as consumers increasingly look to local, home grown produce and opt for foods that are considered to be safer and healthier for you during these unsettled times. Demand for organic foods doesn’t look set to dissipate quickly either once the initial pandemic surge calms. According to the research company Ecovia Intelligence8, which has analysed the buying patterns that followed in Europe after the BSE crisis and in Asia following SARS, demand for organic products will ‘remain strong’ post-Covid.

Delivering organic functional ingredients As more customers proactively seek out stable texture throughout a product’s shelf life. studies was evaluated by ISAPP (International organic solutions, BENEO has been working in Remyline is suitable for fruit preparations, as well as Scientific Association for Pro- and Prebiotics), who partnership with producers, exploring these areas meat and poultry applications. Technical trials by confirmed that inulin and oligofructose are two of further to help them meet the increasing experts at the BENEO-Technology Center have the very few proven prebiotics. consumer demand for organic food and drink shown positive results for these applications, as BENEO’s new Orafti®Organic, is a carefully products. This has led to BENEO recently well as for improving the texture of creamy grown and selected organic variant of its popular announcing the expansion of its chicory root fibre desserts and yoghurts. chicory root fibre and yet another first to market. and rice starch ingredient portfolio with two new The launch of BENEO’s new organic waxy rice It is regionally grown and harvested by certified organic solutions. The launch of the new additions, starch is an important milestone and there is great organic farmers in Belgium. Available to customers comprising an organic waxy rice starch and organic potential for this new solution, especially within from September onwards, Orafti®Organic enables chicory root fibre, paves the way for BENEO to meat and poultry, as consumers worldwide place manufacturers to add natural prebiotic fibres that strengthen its market leading position. special emphasis on organic products when buying will improve taste and texture, while also allowing meat. for fat and sugar reduction in products across key Organic rice starch applications such as dairy, cereals, bakery and Rice is widely considered a familiar and Organic chicory root fibre confectionery. natural product, with 61% of consumers worldwide With three out of four (76%) UK consumers seeing rice starch as natural8. When asked about saying “digestive health is (very) important to Meeting increased customer demand key starch ingredients (rice, corn, potato, tapioca me”10, prebiotic fibres are playing an increasingly BENEO has seen requests for organic variants and wheat), rice came out on top as ‘a cupboard important part in helping boost fibre consumption, constantly growing and is pleased to be the first ingredient’ (67%), ‘healthy’ (58%) and ‘easy to whilst promoting digestive health. Furthermore, functional ingredients provider to be able to offer digest’ (51%). more than half of European consumers associate these solutions to producers. BENEO is confident The addition of BENEO’s new organic waxy prebiotics with helping boost immune health11. this move to expand the overall organic rice starch completes the existing portfolio of This really highlights the growing consumer aware- ingredients portfolio will be highly appreciated by rice starches with the availability of organic ness that a healthy and balanced microbiome has the industry and shows particular promise for new solutions for both regular and waxy rice starch. a positive influence on the overall body. This product developments in this growing area of the Remyline O AX DR is the first of its kind to be remains a big focus for BENEO’s research, market. brought to market, opening up new possibilities especially as inulin and oligofructose, such as those BENEO has two production plants for chicory for product development. As a waxy rice starch, it produced by BENEO, are the only plant-based root fibre – one in Oreye, Belgium and one in contains no amylose and therefore maintains a proven prebiotics. A profound body of scientific Pemuco, Chile. Being located in two different hemispheres, the company also benefits from two harvests per year. There have also been significant investments into the plant for specialty rice ingredients in Wijgmaal, Belgium, in previous years. Only very recently BENEO announced a 50 million Euro investment to increase production capacity in the Wijgmaal plant by 50% by 2022. This infrastructure, combined with BENEO’s extensive planning system, means the company is well prepared to meet increased demand for its organic ingredient offerings.

Putting it into practice BENEO‘s portfolio is based on functional ingredients derived from natural sources. Additionally, the company follows a customer- centric approach and as such, its offerings are largely determined by customer demand. With this in mind, the BENEO-Technology Center works hard to translate these ingredients into versatile recipe concepts for producers to use and adapt in their own facilities. With rice being such an accepted and recog- nisable kitchen cupboard ingredient, BENEO has

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facturers to explore new avenues for organic products across various applications. Thanks to BENEO’s versatile portfolio, the company is able to offer solutions that meet a wide range of end user needs - organically.

References: 1 BENEO Clean Label Consumer Research 2018, conducted by Haystack in Germany, UK, USA (N=3000 (1000/country)). 2 Health Focus International Global Trend Study 2018 3 Mintel Food & Drink (2018, 2019) 4 BENEO Health & Nutrition Survey 2019 West-Europe, N = 3863, average of the countries: BE, NL, UK, ES, FR 5 HFI 2019 6 HFI 2019 7 Soil Association Certification Organic Market Report 2020 8 www.ecoviaint.com/organic-foods-getting-coronavirus-boost/ 9 HFI Global Trend Study 2018 10 FMCG Gurus 2019 11 FMCG Gurus 2020

already worked with manufacturers on a wide following. range of recipe concepts. These include everything The introduction of BENEO’s organic waxy rice from cream cheese, bakery creams, ice creams starch and organic chicory root fibre highlights the and tomato-based sauces, through to spoonable enormous potential for using these ingredients in dressings and ketchups. Thanks to BENEO’s port- organic food and drink products. As consumer folio of specialty rice ingredients, a wide range of interest in natural and organic products continues www.beneo.com

Organic Rice Drink Recipe

INGREDIENTS (% w/w) Test recipe BENEO offers functional ingredients derived from chicory roots, beet sugar, rice and wheat. BENEO is the ideal partner to help organic recipes are now possible, including the to rise, this new capability will enable food manu- improve a product in its nutritional and technological Water 87 characteristics. Key nutritional benefits are ‘less fat’, ‘less Organic rice syrup, organic rice starch & organic rice flour 11 sugar’, ‘less calories’, ‘added fibre’, ‘gluten-free’ and dairy alternatives as well as energy management, digestive, bone Organic sunflower oil 2 and dental health. Key technological benefits focus on taste Minor ingredients (e.g. seaweed, emulsifier, stabiliser) q.s. and texture improvements.Through a unique chain of expert- ise, including the BENEO-Institute that provides decisive insights into nutrition science and legislation, and the BENEO- Organic Tumbled Chicken Breast (phosphate-free) Recipe Technology Center that consults in application technology, BENEO actively supports customers in the development of INGREDIENTS (% w/w) Test recipe Reference more balanced and healthy food products. BENEO is a division of the Südzucker Group that employs more than 1000 people and has production units in Belgium, Chile, Organic chicken breast 87 87 Germany and Italy. Water 11 12 For further information on BENEO and its ingredients, Salt 11 please visit: www.beneo.com and www.beneonews.com or follow BENEO on Twitter: @_BENEO or LinkedIn: Organic rice starch 1- www.linkedin.com/company/beneo6 HFI 2019 Phosphate - q.s.

Corbion granted European patent for fruit ferments

orbion has been granted a European multifunctional, natural solutions throughout Charest commented that the company’s patent for its fruit ferments containing the food industry, this is an exciting milestone for IP-protected technology underpinning the devel- natural organic acids and other flavour us. opment reflects Corbion’s Advance 2025 strategy: compounds. The fruit ferments can be used in a “Fermentation has been one of our core “As well as providing high quality ingredients that range of food applications, including bakery. competencies for nearly a century, and we’re now align with the expectations of today’s consumers, The patent extension now covers Europe, the using nature’s inherent defence mechanisms in new this technology is an excellent representation of US and Japan. ways to maintain and improve quality in the foods Corbion’s current strategy, Advance 2025, which Corbion’s fruit fermentations enable manufac- we all enjoy every day.” seeks to ‘champion preservation in all its forms’,” he turers to adjust flavour profiles and textures of Corbion’s process involves the fermentation of said. baked goods naturally and sustainably; the fermen- liquid fruit preparations – typically citrus and “Aligned with the United Nations’ SDG 2 (zero tations themselves also have natural preservation vegetable-like fruits, including apples, melons, hunger), SDG3 (good health and wellbeing) and SDG qualities. pumpkins and bell peppers – with selected food- 12 (responsible consumption and production), David Charest, vice president, Sustainable Food grade cultures. The resulting metabolites can we’re not only helping preserve our customer’s Solutions at Corbion, said: “With rocketing interest reportedly boost or soften various flavour compo- products, but reduce waste from fruit growers, in fermented foods and the ongoing need for nents and additionally control microbial growth. too.”

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Your one-stop shop for personalised health & nutrition solutions

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BIOXTRACT: Belgian Health Ingredients Group - Member Next generation food supplements

Main products and its categories:

Mental Health Cardiovascular Gut health and Preservation health gut nutrition Clean label/ Aromatization Cholesterol Weight Free from Control, management Immune system Muscle Allergy Prebiotics development Plant based Joint Care Senior Nutrition Sport Nutrition

BioXtract is a manufacturer of Patented Innovative Food Supplements and Standardized Formulated Ingredients for Pharmaceutical and Food Supplement companies. BioXtract’s expertise lies in the development, production and marketing of active ingredients from natural origin, with high added value. These active ingredients are presented in the form of formulated extracts that can be used as ingredients for the manufacture of Food Supplements, but also as ready-to-use finished dosage forms for Private Label Sale. The products are Clinically Proven.

Joint Care: ARANTAL Clear® ARANTAL Clear® is a natural bio-optimized Curcuma longa formulation for the treatment of Osteoarthritis. It has an action on acute and chronic pain. ARANTAL Clear® improves patient’s mobility and also protects the cartilage from degradation. ARANTAL Clear® can also be used to improve healing of muscle and ligament lesions. ARANTAL Clear® is a natural and efficient alternative to classical NSAIDs drugs and painkillers that are Joint Care: CURSOL® having side effects especially for chronic treatments. ARANTAL Clear® CURSOL® is a patented active ingredient offering highly soluble and presents a lot of clinical studies performed on the product itself showing bioavailable Curcumin with powerful anti-inflammatory action. CURSOL® is its high efficacy. particularly designed for all pathologies involving inflammatory processes. Its highly free flowing powder form allows any possible mixture with other Allergy: NASALER® active ingredients for targeting a selected pathology. CURSOL® is one of NASALER® is a natural remedy against the symptoms of Seasonal the most bio-optimized curcumin powder available on the market. Clinical and Non-Seasonal Allergy (Pollen, Animal Air, Pollution, Dust, Mites, Air trial demonstrates its superiority without side-effects on long term Conditioning) containing bioavailable Curcumin and Quercetin offering treatments. relief of the symptoms with long term immunomodulating activity. NASALER® acts on the underlying inflammation, reducing the need for Weight Management: REGULID Plus® medical treatments. As a complement or an alternative to conventional REGULID Plus® is a natural remedy based on the Mediterranean diet medical treatments for allergic rhinitis, it is the first effective natural (Organic Garlic, Olive Oil and Omega-3) acting on the Weight Management alternative of its kind. Taking NASALER® on a chronic basis will gradually by intervening on the metabolism of adipose tissue. The active ingredients increase the tolerance to allergens. of REGULID Plus® have the potential to reduce the low-grade but Chronic Inflammation which is now recognized to play a major role in Gastroenterology: RIFENCIN® cardiovascular risks factor in overweight people. REGULID Plus® acts as a RIFENCIN® is a natural remedy for the relief of Gastrointestinal natural treatment of the Metabolic Syndrome demonstrating its inhibito- disorders (IBS: Irritable Bowel Syndrome) containing bioavailable Curcumin ryeffects on fat cells development. and Fennel Essential Oil. RIFENCIN® has been tested in large scale clinical trials demonstrating its efficiency on the reduction of abdominal pain as well as improvement of the Quality of Life of all the patients. RIFENCIN® can be used on chronic basis without side effects.

Catherine Petit Business Development Director Email: [email protected] www.bioxtract.com

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To face the challenges of tomorrow regarding wellbeing and nutrition, Belgian companies active in health ingredients decided to join forces. In 2012, they created the Belgian Health Ingredients Group (BHIG). It covers several areas of expertise and therefore offers a wide range of solutions responding to specific health challenges in nutrition. All of the ingredients are from natural origin and are designed to meet your strict requirements. The BHIGis intended to propose a complete but customized solution to the health nutrition market.

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COSUCRA: Belgian Health Ingredients Group - Member

A fabulous soluble fibre extracted from the chicory root. A perfect dietary fibre enrichment with a beneficial physiological effect demonstrated by the scientific literature. Categories: Naturally-sourced, Gut health & microbiota, Immune system, Fibre fortification, sugar reduction, fat reduction, Infant nutrition, Clean-label

COSUCRA is a Belgian family owned business established in 1852 and based in Warcoing (Belgium). Originally active in sugar production, the group has undergone a major transformation over the last twenty years to become a pioneer in the production of healthy ingredients derived from chicory and pea. Its pioneering vision on natural ingredients allows COSUCRA to hold an industrial and commercial leadership position in its market. And a constant investment in Research and Development is supporting its major strategy: innovation! Highly nutritious pea protein with quality functionalities. PISANE™ pea protein is the sustainable plant protein solution to plant-based nutrition, Main products and its categories: free-from food and protein fortified products. Categories: Naturally-sourced, Plant-based nutrition, Protein fortifi- Naturally-sourced Plant-based Sugar reduction Weight cation, Weight management, Sport nutrition, Healthy active lifestyle, nutrition management Healthy ageing nutrition, Free-from nutrition, Clean-label Functional Protein Fat reduction Sport nutrition performances fortification Sustainable Gut health & Fibre fortification Healthy active technical solution microbiota lifestyle Savoury market Immune system Free-from Healthy ageing nutrition nutrition Clean-label Infant nutrition A pea cell-wall fibre that meets clean-label and functional challenges of savoury category, and much more beyond. Categories: Naturally-sourced, Clean-label, Functional performances, Sustainable technical solution, Savoury market, Plant-based nutrition

Strength from pea starch. NASTAR™ pea starch is high in amylose and offers unique gelling and thickening properties. Thanks to is functionalities, NASTAR™ is the perfect solution for all food products. Email: [email protected] Categories: Naturally-sourced, Functional performances, Sustainable Eric Bosley technical solution, Savoury market, Clean-label, Plant-based nutrition, Commercial Director Free-from nutrition www.cosucra.com

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Belgian Health Ingredients Group - Member: ENZYBEL

Enzybel specializes in the extraction of enzymes such as Bromelain, Chymotrypsin, Ficin, Pancreatin, Papain, Pepsin, and Trypsin. Enzybel supplies food and beverage, feed and pet food, nutraceutical and O-free pharmaceutical industries. M G With enzymes preparations for food use, containing endopeptidases, commercialized under the generic names: Applicase® Performase® and Xtrase®, we bring natural solutions for protein hydrolyses, seasoning/ tenderizing, gluten transformation, palatability, and the clarification of pilsner beer. Bromelain Main products and its categories: Ficin Food additive Joint health Gut health and Enzyme Papain gut nutrition Processing aid Pharma Plant-derived Animal Derived

Food industries are looking for sustainable activities at all levels of manufacturing – product, process, and system. Enzybel enzymes as a processing aid can contribute to this quest for green manufacturing with their existing portfolio of plant and animal Chymotrypsin derived enzymes. Trypsin The extraction and the refining of Enzybel enzymes do not require polluting or highly demanding energetic processes. Bromelain, ficin and Pancreatin papain are derived from plants that are cultivated in the respect of the environment and in a renewable way, whereas chymotrypsin, pancreatin and trypsin are extracted from the waste of livestock. Our specific catalysts work at a broad range of temperatures and pH and are by consequence energy saving and cost efficient. Out-of-nature, not toxic, 100% biodegradable and very performant make our proteases very popular with many producers in different applications. WWW.ENZYBEL.COM Being an enzyme expert, Enzybel can offer a diversified portfolio of proteases. Products: • Plant-derived enzymes: • Category “Pharma” : Our plant-derived enzymes - Bromelain, Ficin, - Applicase® : Liquid Bromelain Papain, Horseradish peroxidase – and animal-derived enzymes – - Cristalase®: Liquid Papain Pancreatin, Trypsin, Chymotrypsin can be used in Pharma applications - Performase : Papain powder such as Molecular biology and protein research, Peptone manufactur- - Xtrase®: Liquid Papain ing, and Vaccines. - Bromelain powder • Category “Joint health”: Bromelain and Papain are used in Nutraceuticals - Ficin application for joint health improvement and systemic enzymes solution. • Animal-derived enzymes: - Pancreatin - Pepsin - Trypsin - Chymotrypsin

• Category “Food additives” and “processing aid”: Our plant-derived enzymes are used as food additives to modify food properties like digestibility, texture, flavour, structure and shelf life. Our out-of-nature enzymes are processing aids for producers of yeast, proteins, meat/fish, Erwin Kooij dairy, fruit juice and beer. Sales Director • Category “Gut health and gut nutrition” : Our out-of-nature enzymes are Tel: +32 2 353.00.28 also used for natural breaking of large sized molecules of carbohydrates, Mob: +32 473 64.50.42 fats and proteins, in fermentation and preparing predigested protein Email: [email protected] food or preparing amino-acids and specialty foods. www.enzybel.com

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Belgian Health Ingredients Group - Member: HEDELAB

Hedelab, certified ISO 22 000, BIO and HACCP, is an added-value CMO - Capsules: They are available either as powder-based formulas, or plant, (Contract Manufacturing Organization), based in Ghlin (Belgium), nutrient, mineral or vitamin-based formulas Production capacity ranges producing food supplements. Our mission is to support the development from “pilot” batches of 30,000 capsules, up to batches of several of our B-to-C customers, by bringing innovative neutraceuticals solutions millions, and these are available in size 1, 0 and 00 capsules. (powders, liquids, caps, tabs, sticks, Cap Drink,…). We produce liquid and - Liquids: mixtures of vitamins, nutrients, specific plants, in aqueous, hydro- dry galenics for human health, well-being and sport nutrition. Whatever alcoholic form. Ampoules, single doses, shots (10-15ml), plastic or glass your needs in R&D, stability studies, new formulations, aromatization, we bottles (60ml-1L). can support your development from the recipe to the product registration - Tablets: formulas based on powders, plant extracts, nutrients, minerals, thanks to our reactive and interactive approach as well as our 40-years’ probiotics or vitamins. Round or oblong. experience and our flexible industrial tools. - Sticks: mixtures of proteins, sugars, vitamins, plants, probiotics and other nutrients. Production under nitrogen. Film complex: aluminum / PET, Main products and its categories: aluminum / paper. Widths: 17, 25 or 36mm. 1g-10g - Cap Drink: mélanges de protéines, sucres, vitamines, plantes, probio- Mental Health Cardiovascular Gut health and preservation tiques et autres nutriments. PCO 30 (9cc) et PCO 28 (6cc et 22cc). health gut nutrition Clean label Aromatization antioxidant Weight management Immune system Muscle development

- Manufacture and mixing of powders: Hedelab, the pre-eminent nutritional supplement supplier, can offer you bespoke formulations of Christian Gervais proteins, sugars, vitamins, plants, probiotics and other nutrients. These CEO formulations are available in various packaging options (in bulk, in Email: [email protected] containers, jars, sachets, etc) www.hedelab.be

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Belgian Health Ingredients Group - Member: SOTECNA

SOTECNA S.A. is a premium producer/supplier of Natural Ingredients: SOTECNA produces snail SOTECNA supplies the Flavours & Fragrances industries with its 100% pure extracts for cosmetics and and natural Essential Oils, the Cosmetics & Nutraceuticals Industries with its nutraceuticals applications. Snail Extracts, and provides the Food industry with Vanilla beans from Our cosmetic grade snail Madagascar and Papua New Guinea extract, HELISKIN®, is efficiently used into the formulation of skin Main products and its categories: care products like facial creams, body lotions, gels, serums, masks, Clean label Aromatization Joint health Skin care sunscreens, shampoo, … Anti-ageing Cosmetic Food flavouring As a natural source of Allantoin, Hyaluronic Acid, Glucosamine, minerals (Zinc, Calcium, ...), Products: HELISKIN®: 1. Essential oils ² categories food flavouring + aromatization + clean label • Has anti-aging properties Located in the “Land of the • Speeds up the wound healing process Hills" (Pays des Collines) known • complies with the organic standards COSMOS for the cultivation of medicinal • is free from any paraben, silicone, synthetic and petrochemical material plants in Belgium, SOTECNA has • has been in-vivo & in-vitro tested always ensured its sourcing of ² Categories Skin care, Anti-ageing, Cosmetic raw material through local Our food grade snail extract, NUTRELIX®, perfectly fits for nutraceuti- contract farming. cals/cosmeceuticals formulation: Long-term relationships • Speeding up the healing process of skin tissues through its natural source with local farmers have been of Allantoin, Hyaluronic Acid and Glycosaminoglycans ² Category “Skin allowing SOTECNA to develop care” its traditional expertise by find- • Giving strength and elasticity to the joint cartilage thanks to its natural ing the most optimal soil conditions for the production of its essential oils. content of Allantoin, Glucosamine and Chondroitin Sulfate ² Category SOTECNA produces 100% pure and natural essential oils “Joint health” - In respect with our traditional know-how • Providing Anti-inflammatory properties - Trough steam distillation process - From local farmers to our distillation site 3. Vanilla beans - Ensuring a full traceability SOTECNA steps into the • Angelica essential oil Vanilla business with the Known for its old and traditional flavour, Angelica essential oil is used support of its sister companies as a flavouring ingredient. Angelica root essential oil is one of the main KAMAPIM, Papua New Guinea flavoring ingredients in liquors such as gin, Benedictine, chartreuse, triple & SOPRAL, Madagascar. sec. SOTECNA aims at produc- Angelica root essential oil is also widely used in the perfume industry. ing and supplying high added • Horseradish essential oil value products from natural Horseradish essential oil is used as a flavouring ingredient in sauces, resources. In cooperation with marinades and dressings for prepared food, sushi & raw fish, hummus, and our sister companies KAMAPIM pickles vinegar. in Papua New Guinea and Horseradish essential oil is also famous in a wide range of snacking SOPRAL in Madagascar, we have created BelVanilla: your Vanilla connec- applications: Nuts, Nacho crisps, rice savoury snacks, potato chips, roasted tion from cultivation to distribution. green peas, Pretzels, Pop corns and wicked sticks. BELVANILLA answers to your needs in Vanilla beans for extraction and The roots of the horseradish have a strong taste, spicy and pungent. gourmet use. Thanks to our local presence in Madagascar and Papua New It participates to trigeminal sensation. Guinea, we are able to guarantee a short supply chain from cultivation in • Lovage essential oil origin to distribution by SOTECNA in Belgium. The volatile oil extracted from the roots is widely used as a flavour What we offer: enhancer in instant soups, ramen, stock cubes and ready meals. Expertise Lovage Essential Oil is known for its Umami taste, giving a natural A twenty years expertise in the field of the Queen of Spices in alternative to Monosodium glutamate (MSG). Madagascar Secured supply chain and Traceability 2. Snail extracts We have established long-term and stable relationships with local Did you know Allantoin is the main active ingredient found in Snail farmers allowing us to ensure a full traceability Extracts? Quality Control Snail secretion filtrate became a cosmetic ingredient when snail Through traditional and quick curing process methods in our own farmers realized snails’ secretion was able to reduce the visual aspect of processing facility we have established strict Quality Control procedure to their scars on their hands. select and sort the Vanilla beans Indeed, snails are able to regenerate their broken shell thanks to the Commitment and social engagement natural active ingredients found in their secretion: natural Allantoin, We aim at organizing our sourcing of Vanilla beans in ways that Hyaluronic Acid, Glycosaminoglycans and various minerals (Zinc, Copper, respect and preserve the environment, and stimulate the development Calcium, Magnesium). These active substances are well known for their cell and well-being of local communities. We guarantee that fair prices are paid regeneration properties. directly to the farmers. As main component of the snail secretion filtrate, Allantoin provides intense moisturization that helps reducing the appearance of expression lines and improve skin’s elasticity. Widely used in skin care and dermo cosmetics, Allantoin is the perfect ingredient for dry and damaged skin. It is an effective healing agent that stimulates cell proliferation and healthy Sotecna tissue formation. Adèle Nowak The natural presence of other active substances like Hyaluronic Acid Account Manager and Glycoaminoglycans makes our snail extract your perfect naturally- Email: [email protected] derived ingredient for your skin care routine. www.sotecna.com

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Belgian Health Ingredients Group - Member: THT Lactobacillus casei

Main products and its categories: Lactobacillus rhamnosus Probiotics food Probiotics food Bioprotective Probiotics finished Fructo oligosaccharide prebiotic supplements ingredients cultures products Maltodextrin Pure cultures in bulk Dairy products and Against spoilage Private formulations Gluten, paraben and alcohol free bakery Blends in bilk Oenology and sausages Against Listeria THR formulations Presentation monocytogenes Cardboard box size containing 15 sticks Sachet net weight 1 gr Flavour vanilla or strawberry Since 1991 THT has specialized in the selection PROFEM and production of freeze-dried probiotics for Nutritional supplement for a balanced vaginal Directions the nutraceutical industry (weight loss, immune flora 1 - 2 sticks per day enhancement, prevent tract-infections...), food ingredients industry (daily products, oenology, Indication bakery, sausages), bioprotective cultures (fight Suitable for female adults over 15 years old PROBITEK PLUS against spoilage and Listeria monocytogenes) Reinforce restoration microflora after antibiotic and animal feed industries (natural growth Concentration diarrhea treatment additives and relaxation). We also provide 2,5E+09 CFU/g private strain growth services for our clients. Our 1,0+09 CFU/capsule Concentration reputation has been built around a unique 2,0E+10 CFU/g “savoir-faire” to control steps of selection and Composition 8,0E+09 CFU/capsule production. Our strains are specifically selected Bacillus caogulans for their technological and health benefits by Lactobacillus acidophilus Indication our highly qualified team of scientists. We are Lactobacillus crispatus Suitable for adults over 15 years old able to supply either pure cultures or blends in Lactobacillus rhamnosus bulk, as well as full-service finished products. For Maltodextrin Presentation the later, we are proud to offer our clients a Cardboard box containing 2 blisters x 15 caps wide range of THT formulations already Presentation registered and ready to market rather than Cardboard box containing 2 blisters x 15 caps Composition spending unnecessary time in development Saccharomyces boulardii with tailor made formulations. THT formulations Directions Bifidobacterium animalis lactis span several therapeutic areas answering the 1 - 2 caps per day Bifidobacterium breve market demands. Recently we also extend our Bifidobacterium longum offer by providing probiotic ingredients for the Lactobacillus casei cosmetic industry. Quality control, affordable PROKIDSPLUS Lactobacillus plantarum prices and flexibility are our top priorities. All our Balance Microflora and improve Intestinal tran- Lactobacillus rhamnosus productions are allergens free, available kosher sit Corn maltodextrin or halal. Magnesium gluconate Indication THT formulations of finished products: Suitable for children over 3 years old Directions Developed by our board-certified R&D team, 1 - 2 caps per day after or during meals THT offers two different products dedicated to Concentration woman health to restore their intimate balance 1,0E+09 CFU/g/stick (PROFEM and PROLACTYS FEMINA). Also, PROLYTE because we think that building a strong immune Composition Reinforce microflora restoration after antibiotic system should start early in life, THT has Bacillus caogulans treatment developed two products specially for kids Bifidobacterium adolescentis (PROKIDSPLUS and PROLACTYS KIDS). We also Bifidobacterium breve Indication take care of various troubles that could happen Bifidobacterium infantis Suitable for healthy adults during life, that’s why THT has developed one Lactobacillus acidophilus anti-diarrhea formulation (PROBITECK PLUS), one for transit and bloating (PROLACTYS ADULTS), one to restore microflora after antibiotic treat- ments (PROLYTE), one for weight loss (PROLEAN) and one for sportive people (PROBIOMINE). We can provide on demand genetic identification of THT probiotic strains. Our formulations have been developed in a way to resist the worst climatic conditions for probiotics like hight humidity and hight temperatures. We also use the best existing packing techniques like 100% organic gastro resistance DRcaps. The later protects bacteria from acidity stress during stomach’s passage. Pick your THT finished product formula- tions, send us your own packaging design and we are all set to provide you with the finished product.

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Belgian Health Ingredients Group - Member: THT Presentation Concentration Indication Suitable for children over 3 years old

Concentration 2,0 E+10 /stick

Composition Lactobacillus sp. Bifidobacterium sp. Bacillus sp. Saccharomyces boulardii Fructo oligosaccharide prebiotic Gluten, paraben and alcohol free

Presentation Cardboard containing 10 sticks Sachet net weight 2 g Flavour vanilla or strawberry Cardboard box containing 10 sticks of 2,5 gr Concentration 3,0E+08 CFU/g Directions Concentration 1 - 2 sticks per day 1,6E +09 CFU/g Composition Lactobacillus casei Composition Lactobacillus reuteri PROLACTYS Adulte Bacillus caogulans Lactobacillus rhamnosus Balance intestinal microflora Lactobacillus acidophilus Maltodextrin Troubles digestives Lactobacillus casei L-glutamine Transit and bloating Lactobacillus rhamnosus Inulin Prebiotic Presentation Concentration Corn maltodextrin Cardboard box containing 10 sachets of 15 gr 2,0E +10 CFU/capsule Magnesium gluconate Sodium chloride Directions Indication Potassium chloride 1 sachet per day to add to drinks Suitable for adults over 15 years old Natural vanilla flavour Presentation Directions Cardboard 2 x 15 caps gastro resistant 1 - 2 sticks per day PROLACTYS, top of the line formulation range Composition PROLACTYS FEMINA Bifidobacterium animalis ssp lactis PROLEAN Balance and restore vaginal microflora Bifidobacterium bifidum Reinforce weight management Digestives troubles and urinary troubles Bifidobacterium infantis Bifidobacterium longum Indication Indication Bifidobacterium breve Suitable for healthy adults Suitable for female adults over 15 years old Lactobacillus acidophilus Lactobacillus brevis Concentration Concentration Lactobacillus casei 1,2E+10 CFU/g 2,0 E+10CFU/g Lactobacillus plantarum 5,0+09 CFU/capsule 8,3 E+09CFU/ capsule Lactobacillus rhamnosus Lactobacillus salivarius Composition Composition Lactococcus lactis Bacillus caogulans Lb crispatus Streptococcus thermophilus Bifidobacterium animalis lactis Lb acidophilus Bacillus coagulans Lactobacillus gasseri Lb rhamnosus Saccharomyces boulardii Lactobacillus plantarum Bacillus coagulans Inulin prebiotic Lactobacillus rhamnosus Corn maltodextrin Fructo oligosaccharide prebiotic Inulin prebiotic Cranberry extract 30% PAC’s Corn maltodextrin Fructo oligosaccharide prebiotic Silicon dioxid Corn maltodextrin Magnesium stearate Directions Magnesium gluconate 1 - 2 caps per day after or during meals Presentation Presentation Cardboard containing 30 caps / CSP technolo- Packing Cardboard box containing 2 blisters x 15 gies jar caps Directions Directions 1 - 2 caps per day 1 - 2 caps per day

PROLACTYS Kids Contact person: PROBIOMINE Balance Microflora Constance Clarisse Muscle growth and maintain healthy immune Improve Intestinal transit Sales and Marketing system Email: [email protected] www.tht.be

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Belgian Health Ingredients Group - Member: TARADON LABORATORY

Main products and its categories: Lactoferrin Since 2017, Taradon Laboratory created its subsidiary Taradon Personal Care, which aims to improve Quality of Life by reinforcing deficiencies in natu- Mental Health Immune system Gut health and antioxidant rally occurring physiological mechanisms in order to promote human gut nutrition health, wellbeing and comfort in the way nature intended. Taradon Personal Care develops and bring to market unique healthcare TARADON LABORATORY studied the secretion fluids of the human body and products which harness the scientific and technical expertise of Taradon their composition. We are therefore specialized in the production of Laboratory. lactoferrin, lactoperoxidase, which are the main molecules of these We specialize in researching and applying the health-promoting protective fluids. Based on our experience and our scientific knowledge, we properties of naturally-derived milk and plant molecules which are develop finished products based on its bio-active ingredients. biologically equivalent to those present in human secretion liquids. Lactoferrin is an iron binding glycoprotein. We find it in the cow milk, The AnOxident balance mouthcare products support the microbial but it is a prominent component of all mucosal secretions and it can be stability of the mouth, helping overcome and prevent mouth problems detected in almost all body fluids. Most of the biological functions of linked to compromised or deficient saliva. lactoferrin are related to the importance of iron. Main references : ALAXIA (Meveol). Taradon Laboratory develops finished product formulations for clients using our very own products. Certification : HACCP

Taradon Jean-Baptiste Morel Export Manager Email: [email protected] https://anoxident.org/en/our-team/

Belgian Health Ingredients Group - Member: Vésale Pharma

The Belgian Vesale Pharma Cy specializes in R&D on probiotic solutions. As a pioneer company, Vésale Pharma dedicates 23% of turnover in R&D every year and works with major Belgian and international Universities or Institutes (e.g., the Pasteur Institute of Lille-France or Texas A&M University-USA). Products are sold in more than 20 countries worldwide through a network of distributors. Vésale holds 6 worldwide patents, including the patent Intelicaps®, a world unique revolutionary technology of probiotics micro-encapsulation.

ADDED VALUE The two main added values are the Research-based products range with documented strains and the world unique revolutionary technology of probiotics micro-encapsulation called Intelicaps®. Intelicaps® increases dramatically the survival of live probiotics through gastric passage and is in fact an excellent colonic delivery system. This ends in a 1.000 times higher survival and availability of live probiotics compared to conventional lyophilized.

RANGE OF PRODUCTS The actual probiotic products’ portfolio covers 4 ranges of probiotics representing not less than 14 products for export: The Pediatric Range, the Women’s health Range, the Adults Range (metabolic products/ intes- tinal health) and the especially designed Senior Range. In 2020 the company is launching a new exciting product Bactimun to strengthen immunity. The product contains a novel probiotic strain, Lactobacillus johnsonii 456, which proved colonizing the intestinal tract for a prolonged period of more than 60 days after a one-week intake. Different other new products are in development at present.

Contact details: Vesale Pharma Rue Louis Allaert 9 B- 5310 Noville-sur-Mehaigne Tel: +32 81 560006 Email: [email protected] Email: [email protected] www.vesalepharma.com

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Create a visual feast with food colouring!

By Joy Thomas, Technical Business Development Manager at Cornelius

n today’s food and drink retailing world, prove a detriment to products that feature more with the rise of clean labelling and a renewed focus brands excel or falter by their ability to subdued colours. on authenticity, transparency and provenance. address the latest consumer trends. One solution that Cornelius offers to the With this, we also see a real push on ingredients Shoppers are continuing to fuel food sector is I-COLORS selection from Chr Hansen. that keep products as close to nature as possible, product innovation and are backing Specifically design to give real visual impact to with a reduction in synthetic components. One of adventurous brands with their wallets. beverages, the range uses next-generation the challenges for food manufacturers looking to The colour of food is often at the centre of ingredients and technology to replace artificial boost consumer appeal is reducing the number of trends as food and drink continues to move colourings. The I-COLORS spectrum of yellows and artificially derived additives, particularly when it from a physiological necessity to a consumer oranges to deep reds and purples includes comes to colours and flavours. experience. What’s driving this imperative and why responsibly sourced anthocyanins, carotenes, FRUITMAX® is a great example of where has colour become so crucial? Moreover, how can annatto and curcumin to create products that vibrant, naturally derived colour can be used to food manufacturers ensure that their product capture the eye, as well as the imagination. great effect. The range available from Cornelius, development process is putting consumer needs developed by food colour specialist Chr Hansen, at the heart? Plant-based protein adds a new dimension of eye-catching appeal with The rapid growth of plant-based ‘meats’ is a vivid, heat-stable colouring food stuffs. Instagram-ability great example of where food colouring becomes FRUITMAX is a plant-based portfolio of red and We’re in a market where products don’t have so crucial. Market intelligence agency CB Insights oranges shades, derived from sweet potato. The to simply be functional, they have to camera-ready has projected that the long-term global market colourings are ideal for a wide range of food at all times, whether home baking, pre-prepared for ‘meatless food’ will reach an astonishing applications, including confectionary, beverages, meals, individual ingredients or otherwise. $2.7 trillion by 2040. The break-neck speed of this baked goods and breakfast cereals, to name just a Take some of the most significant (and category’s growth has therefore captured the few. The FRUITMAX® range is proving a real hit with profitable) trends from the last several years such attention of food brands across the world. consumers because it’s a vegan-friendly alterna- as plant-based proteins, artisanal shakes and the These products are increasingly designed to tive to carmine, sunset yellow and allura red, with continued acceleration of home baking, and what resemble their meat counterparts over natural no off-flavour giving it enviable versatility. they have in common is that they’re Instagram- colouration. The increasing demand for meat The range also boasts impressive heat, light ready and in full colour. We don’t see food trends alternatives is set to continue accelerating the and oxidisation stability. Consumers are taking captured in black and white because colour is such plant-based food colouring category, as brands ingredients listings and authenticity much more an intrinsic part of the food experience. look to create vegan products without sacrificing seriously now than they have in the past, and It has never been more important for brands aesthetic value. complex E-numbers and additives are proving a to harness colour as a real advantage. Our senses At Cornelius, we have seen this used to great turn-off. This is contrary to the positive message don’t work independently of each other; a great effect first-hand, shaping our offering to the food of many healthier foods today, marking flavour experience isn’t enough on its own, taste is manufacturing sector accordingly. We work with FRUITMAX® out as an ideal alternative. inextricably linked to the aesthetics. The appear- brands to offer a range of ingredients and The colour of food is one of the key decision- ance of a product gives it symbology and meaning components that meet consumer trends head-on making factors for consumers. Brands that boost and sets an expectation in the blink of an eye. and impart marketable benefits directly into the visual appeal as part of their product value Studies have shown time and again that the product from the outset. proposition can leverage a key competitive edge combination of colour and flavour is an important As plant-based proteins continue their in the race for market share. The team at Cornelius component of the experience1, and as consumers impressive growth, we expect to see heightened specialises in helping brands to really wow the demand more food-like nutraceutical products, demand for reds, browns and purples to create a consumer with bold colours and has a compre- this discussion needs to be had at the very start of visual experience that replicates traditional meat hensive portfolio of options to meet the latest the NPD process. Colour creates a psychological dishes. trends and consumer needs. expectation that cannot easily be broken down or assuaged. Colours that ‘keep it natural’ Reference: 1 https://flavourjournal.biomedcentral.com/articles/10.1186/s13411-015-0031-3 By creating a more vibrantly coloured product, As food and health become more closely brands are creating value for the consumer. We linked, consumers are taking a more proactive now expect our food to look great, which can approach to their wellbeing. We have seen this www.cornelius.com

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Anti-inflammatory activities of Naticol® demonstrate benefits in ageing

Author: Dr. Christelle Bonnet

geing may be considered as the and even in how well it ages. According to the Interestingly, it has also been shown that collagen accumulation of diverse deleteri- literature, collagen peptides may slow down the hydrolysates inhibit zymosan- induced inflamma- ous changes in cells and tissues collagen disorganization and destruction associ- tion (Hartog et al., 2013). (skin, joints…). One of the major ated with dermal atrophy and skin aging. Scanning In this article, we would like to point out how changes that occur during ageing electron microscopic examination shows that the Naticol® (specific fish collagen peptides) may exert is the dysregulation of the immune response, number and width of collagen fiber bundles its benefits in skin beauty and articular comfort leading to a chronic systemic inflammatory decreases with age. through an acceleration of collagen synthesis and state. Among the dysregulated proinflammatory Naticol®, natural fish collagen peptides devel- anti-inflammatory activities. mediators, cytokines and chemokines are major oped by Weishardt group is clinically substantiated culprits in the development of chronic inflamma- to improve skin elasticity and reduce skin wrinkle In vitro benefits of Naticol® on matrix tion and the immunosenescence process. appearance through an acceleration of collagen metalloprotease and collagen synthase For instance, interleukin (IL)-6, tumor synthesis and inflammation resolution. expression necrosis factor (TNF)-␣, and their receptors, are Within the joint, intra-articular administration Human monocyte-derived macrophages upregulated in aged tissues and cells (Bruunsgaard of collagen in the knee in patients with (h-MDMs) and keratinocytes (HaCat) were co-culti- et al., 2003). Michaud et al. have shown that two osteoarthritis significantly decreases local inflam- vated in transwell culture system. to four-fold elevations in the circulating levels of mation (increase in T regs, IL-10 and decrease in The cells were stimulated with LPS (100ng/ml) inflammatory cytokines, such as TNF-␣, IL-6, and IL- I L- 1 ␤) and attenuates the symptoms inherent to to induce a pro-inflammatory phenotype and then 1␤ are typically observed in the elderly compared the pathology (Furuzawa-Carballeda et al., 2012). to the young. Similarly, oral administration of collagen in mice Skin ageing answers to this chronic inflamma- with post-traumatic osteoarthritis inhibits synovial tory state. Additionally, skin ageing, in particular, inflammation and induces cartilage regeneration skin appearance being a primary indicator of age, (Dar et al., 2016). Naticol® has also clinically demon- with skin becoming unevenly coloured, lax, dry as strated its benefits in physical function to alleviate it ages, a solution targeting skin appearance and osteoarthritis symptoms. In metabolic disorders, it specifically inflammation resolution seems relevant. is suggested that the oral administration of We believe collagen peptides can make an collagen improves metabolism by directly targeting important difference in the way the skin looks inflammatory processes (Astre et al., 2018). were traited by Naticol®. The expression of Collagen Synthase 3 (enzyme involved in collagen production), of Metallopeptidase 13 (MMP13 involved in the breakdown of extracellular matrix and tissue remodeling), TGF␤ and IL-10 (anti-inflammatory and proresolutive cytokines) were evaluated by real-time qPCR. Results showed a significant increase of the collagen synthesis through a decrease of the matrix metalloproteases and an increase of the collagen synthesis.

Naticol® and anti-inflammatory activities Research has been conducted to determine the effects of collagen peptides on inflammation. Indeed, it has been shown, in vivo, that MR (Mannose Receptor) specifically expressed by M2-like macrophages is responsible for the recog- nition and endocytosis of collagen across the fibronectin type II domain and recognizes both native collagen and hydrolyzed collagen peptides (Curino et al., 2005; Eichele et al.,2017; Engelholm et al., 2009; Madsen et al., 2013; Malovic et al.,2007; Melander et al., 2015; Napper et al., 2006; Seikh et al. 2000). In our experiment, Naticol® was associated with lower levels of TNF-␣ and IL-1␤ pro-inflammatory cytokines. The attenuated

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inflammation by Naticol® treatment was also quently, Naticol® is the ideal ingredient delivering References: supported by induced TGF␤ and IL-10 anti-inflam- wellbeing and anti-ageing benefits. Astre G, Deleruyelle S, Dortignac A, Bonnet C, Valet P, Dray C. Diet-induced obesity and associated disorders are prevented by natural bioactive type 1 fish matory cytokines secretion. Make your move in the anti-ageing category collagen peptides (Naticol®) treatment. J Physiol Biochem. nov 2018;74(4):647_54. Anti-inflammatory properties of Naticol® have with Naticol®, specific fish collagen peptides Bruunsgaard H, Ladelund S, Pedersen AN, Schroll M, Jørgensen T,Pedersen BK (2003). Predicting death from tumour necrosis factor-alpha and interleukin-6 in been demonstrated in pre-clinical studies. Conse- from WEISHARDT ! 80-year-old people. Clin Exp Immunol, 132: 24-31. Curino AC, Engelholm LH, Yamada SS, Holmbeck K, Lund LR, Molinolo AA, et al. Intracellular collagen degradation mediated by uPARAP/Endo180 is a major pathway of extracellular matrix turnover during malignancy. J Cell Biol. 2005;169(6):977_85. Dar Q-A, Maynard RD, Liu Z, Schott EM, Catheline S, Mooney RA, et al. Oral hydrolyzed type 1 collagen induces chondroregeneration and inhibits synovial inflammation in murine posttraumatic osteoarthritis. Osteoarthritis Cartilage. 2016;24:S532_3. Eichele DD, Kharbanda KK. Dextran sodium sulfate colitis murine model: An indispensable tool for advancing our understanding of inflammatory bowel diseases pathogenesis. World J Gastroenterol. 7 sept 2017;23(33):6016_29. Engelholm LH, Ingvarsen S, Jürgensen HJ, Hillig T, Madsen DH, Nielsen BS, et al. 2009;14:2103_14. Furuzawa-Carballeda J, Lima G, Llorente L, Nuñez-Álvarez C, Ruiz-Ordaz BH, Echevarría-Zuno S, et al. Polymerized-type I collagen downregulates inflammation and improves clinical outcomes in patients with symptomatic knee osteoarthritis following arthroscopic lavage: a randomized, double-blind, and placebo-controlled clinical trial. ScientificWorldJournal. 2012;2012:342854. Hartog A, Cozijnsen M, de Vrij G, Garssen J. Collagen hydrolysate inhibits zymosan-induced inflammation. Exp Biol Med Maywood NJ. 2013;238(7):798_802. Madsen DH, Leonard D, Masedunskas A, Moyer A, Jürgensen HJ, Peters DE, et al. M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway. J Cell Biol. 16 sept 2013;202(6):951_66. Malovic I, Sørensen KK, Elvevold KH, Nedredal GI, Paulsen S, Erofeev AV, et al. The mannose receptor on murine liver sinusoidal endothelial cells is the main denatured collagen clearance receptor. Hepatol Baltim Md. juin 2007;45(6):1454_61. Melander MC, Jürgensen HJ, Madsen DH, Engelholm LH, Behrendt N. The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review). Int J Oncol. 2015;47(4):1177_88. Michaud M, Balardy L, Moulis G, Gaudin C, Peyrot C, Vellas B, et al. (2013). Proinflammatory cytokines, aging, and age-related diseases. J Am Med Dir Assoc, 14: 877-882. Napper CE, Drickamer K, Taylor ME. Collagen binding by the mannose receptor mediated through the fibronectin type II domain. Biochem J. 1 mai 2006;395(Pt 3):579_86. Sheikh H, Yarwood H, Ashworth A, Isacke CM. Endo180, an endocytic recycling glycoprotein related to the macrophage mannose receptor is expressed on fibroblasts, endothelial cells and macrophages and functions as a lectin receptor. J Cell Sci. mars 2000;113 ( Pt 6):1021_32. 30

For more information, please contact: WEISHARDT INTERNATIONAL Rond-point G Jolimaitre - BP259 81305 GRAULHET Cedex FRANCE Tel: +33 (0) 5 63 42 14 41 Email: [email protected] www.weishardt.com

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Cultures that matter

A time-tested yeast culture, mastered and perfected from lab to shelf

. boulardii was discovered in 1923 by a dysbiosis event, tight junctions might be • The stimulation of the immune system and ; Henri Boulard, during a cholera disrupted and pathogens contamination risks • The modulation of the immune signaling epidemic in Vietnam, on tropical increases. As an ally, S. boulardii will preserve and pathways. fruits skin and was first marketed in strengthen tight junctions of enterocytes. 1953 as a drug to prevent acute • The role of S. boulardii is also to protect intestinal diarrhea. Since then, it has been analysed in over mucosa metabolism and ecosystem through a Research and development teams devel- 100 clinical studies with a focus on gut health. communication with epithelial cells line. It helps oped an immune microarray to understand the S. boulardii is a safe and reliable probiotic to the body to absorb nutrients and enhance the influence of the yeast on the host-response support several gastrointestinal conditions such as release of specific enzymes, to increase the level system at a cellular level. During a dysbiosis preventive treatment of antibiotic-associated of short chain fatty acids (SCFAs) restoring the event, alterations in immune system can diarrhea or traveler’s diarrhea and intestinal normal colonic fermentation and absorption. appear with the net result being a pro-inflam- disorders due to Clostridium difficile and Finally, it also provides an antioxidant activity. matory response. Audy revealed in its in vitro Helicobacter pylori infections. Suitable for both study that S. boulardii by Lallemand decreased children and adults, this particular yeast is highly Immunity modulation the expression of a set of core gene involved in recommended by pediatric associations since • S. boulardii has a strong impact on the immune pro-inflammatory cytokines production such as decades for its gut health benefits, at a suggested system at different levels: the chemokine IL-8. dose between 250mg to 1000mg per day. S. boulardii can also be used as an adjunct to rehydration therapy in the management of acute Lallemand Health Solutions demonstrated the SCIENTIFIC EVIDENCE diarrhea in children. It has shown to reduce the antioxidant activity and the SCFAs increase Harnessing the synergistic effect of duration of acute diarrhea by approximately one production of its yeast Saccharomyces S. boulardii CNCM I-1079 combined day. boulardii CNCM I-1079 in an in-vitro model with bacteria simulating gastrointestinal environment after Two types of microorganisms have been MECHANISM OF ACTIONS the addition of C. difficile. The studies successfully used as probiotic for decades: The mechanistic modes of action have been performed by Gaisawat and published in 2019, bacteria, mainly from the Lactobacilli and widely documented by strong scientific evidences shows that S. boulardii restored altered redox Bifidobacteria species; and yeast, most particularly proving the effectiveness of the probiotic yeast status associated with C. difficile infection by Saccharomyces cerevisiae boulardii. Both have S. boulardii [Pais 2020], [Kelesidis 2012]. significantly increasing copper chelation (p different and complementary properties and <0.05), thereby reducing the metal’s bioavail- modes of action to account for their clinical Luminal effect ability used to catalyze free radical polymeriza- benefits. • S. boulardii exerts an antimicrobial action by tion. S. boulardii also significantly increased A core of science exposes the synergy, dual interfering directly or indirectly with opportunis- total SCFAs production (p <0.05), especially action and proven benefit of combining yeast and tic bacteria to inhibit their growth or their acetate and butyrate, and restored H2S level bacteria. The two microorganism’s dissimilar attachment to human enterocytes cells through (p <0.05), improving metabolic dysregulation functions and attributes put forth complementary a specific binding. The mannose-dominant outer associated with C. difficile infection. modes of action bringing synergistic effects and membrane of the probiotic yeast acts as a decoy, additional benefits. While yeast binds to pathogens it attracts pathogens on its surface to finally eliminate them in the stools. Probiotic bacteria Probioticrobiotic yeast – S.Sb boulboulardiiboullararrdiidii • S. boulardii is also able to release specific proteins • • that inactivate the metabolites of opportunistic ProkaryoteProkaryote cecells.lls. Unicellular eeukaryoteukaryote organismorganism with cecellll wall.wall. bacteria thus providing a neutralizing effect. • Shape: Coccus (spherical),(spherical), • Literature showed that S. boulardii produces a bacillus (rod-shaped).(rod-shaped). Shape: OvOvoidoid or spherical.spherical. protease which inactivates toxin A of Clostridium • Size:Size: ~~1 1 µm. • SizSize:e: ~ 10 µm. difficile and lyses the receptors for this toxin • Metabolism:Metabolism: Wide varietyvariety ttoo • MeMetabolism:tabolism: LivLiveses in the [McFarland 2010]. ƐƵƌǀŝǀĞƐƵƌǀŝǀĞ ĞdžƚƌĞŵĞĞdžƚƌĞŵĞ ĐŽŶĚŝƟŽŶƐ͘ĐŽŶĚŝƟŽŶƐ͘ pr presenceesence or absenceabsence of O2. • ZĞƉƌŽĚƵĐƟŽŶ͗ZĞƉƌŽĚƵĐƟŽŶ͗  LJLJ ĐĞ ĐĞůůůů ĚŝǀŝƐŝŽŶ • ZZĞƉƌŽĚƵĐƟŽŶ͗ĞƉƌŽĚƵĐƟŽŶ͗  LJLJ ďƵĚĚŝŶŐ͘ everyevery 20-30 minutminutes.es. Trophic action • WƌWƌĞƐĞŶĐĞĞƐĞŶĐĞ ŝŶ ƚŚĞ ŵŝĐƌŽŇŽƌĂ͗ŵŝĐƌŽŇŽƌĂ͗ ф ϭй͘ • Intestinal epithelial cells also known as enterocytes • WƌĞƐĞŶĐĞWƌĞƐĞŶĐĞ ŝŶ ƚŚĞ ŵŝĐƌŽŇŽƌĂ͗ŵŝĐƌŽŇŽƌĂ͗ ϵϵй͘ • ^Ğ^ĞŶƐŝƟǀĞŶƐŝƟǀĞ ƚ ƚŽŽ ĂŶ ĂŶƟĨƵŶŐĂůƟĨƵŶŐĂů ĂŐ ĂŐĞŶƚƐ͘ĞŶƚƐ͘ play a key role against external bacteria. Their • ^ĞŶƐŝƟǀĞ^ĞŶƐŝƟǀĞ ƚ ƚŽŽ ĂŶ ĂŶƟďŝŽƟĐƐ͘ƟďŝŽƟĐƐ͘ tight junctions ensures the barrier impermeabil- ity, therefore avoiding bacterial infiltration. During Figure 1: Probiotic bacteria and probiotic yeast features

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with its specific receptors on its cell wall, bacteria Protecflor® product or saline solution as placebo. A by rotavirus and also showed interesting results on have an antimicrobial activity through the produc- fifth group uninfected by E. coli ETEC was also used yeast and bacteria combination. In the first one tion of particular metabolites. Furthermore, as control. Results showed a significantly greater [Grandy 2010], 64 infants aged from one to looking at epithelial cells level, yeast communicates effect with Protecflor® compared to placebo or 23-month-old hospitalized with acute rotavirus with epithelial cells as well as the intestinal S.boulardii alone or the bacteria mix in several diarrhea took oral rehydration solution (ORS) with microflora thus preserving barrier integrity and parameters including body weight loss (p = 0.02), or without probiotic combination twice daily for supporting a favourable environment for the body temperature (p <0.02) or modulation of five days. In the second one [Teran 2009], the microflora balance, whereas bacteria also compete inflammatory cytokines response (p <0.03). In protocol included 75 infants from one to with pathogens for adhesion to epithelial cells and addition, no diarrhea at all were observed in the 24-month-old with the same health conditions for nutrients. Finally, both yeast and bacteria are Protecflor® group in this in vivo model. split the same way, ORS with or without probiotics able to stimulate and modulate the immune Grgov also confirmed the effectiveness of during same period. Both assessed the efficiency system to help the body’s defenses. Protecflor® in a randomized controlled trial of probiotic yeast and bacteria strains combination performed on 167 adults with Helicobacter pylori by revealing that the probiotic product acted on the significant reduction of vomiting duration compared to control (0 vs. 42.5 hours, p = 0.041) and the decrease of diarrhea duration (60 vs. 84.5 Probiotic Bacteria strains Probiotictic YYeasteast S.. boulardii hours, p = 0.06) in the first trial [Grandy 2010]; and by significantly decreasing the duration of hospitalization (72 vs. 108 hours, p = 0.017) and Opportunistic bacteria diarrhea (48 vs. 79 hours, p = 0.009) compared to control in the second study [Teran 2009]. Luminal ėǛėĉƢ Opportunistic bacteriaeria Antimicrobial binding and activity neutralizing effects S.boulardii CNCM I-1079 and L. rhamnosus GG combination Competition In 2019 Moens evaluated the effect of the for adhesion and nutrientss most documented probiotic yeast S. boulardii and Communication ··ƎŧƊĸĽĉƎŧƊĸĽĉ ìĉƢĽŧŞ and preservation of the famous probiotic bacteria L. rhamnosus GG intestinal mucosa when combined together in an in vitro model simulating the human microbiota of the gastroin- testinal tract after an infection with E. coli ETEC. Cross-talk After dysbiose induction of the microbiota due to and stimulation the enterotoxigenic bacteria, 48 hours incubations TśśƫŞĽƢlj śŧĐƫœìƢĽŧŞ Epithelial cells ImmuneImmunne cells were done with S. boulardii CNCM I-1079 alone or AdaptedAdaaptedpted from Kelesidis, 2012 L. rhamnosus GG alone, or both probiotics in combination. Results exposed a significant greater decrease of E. coli toxin concentration as well as E. coli concentration with S. boulardii in combina- Dual actionction of yeast and bacteria tion with L. rhamnosus GG compared to control.

Combination with other powerful Figure 2: Complementary modes of action of probiotic yeast and probiotic bacteria for additional benefits ingredients Lallemand Health Solutions continues its The following positive outcomes and administrated with a triple eradication therapy research to find new ingredients to combine with demonstrate the synergistic effect of for seven days with or without probiotic combina- its probiotic products to confer a synergetic effect. the yeast and bacteria combination. tion for four weeks. Protecflor® significantly Therefore, Lallemand Health Solutions can provide increased H. pylori eradication rate combination of S. boulardii with prebiotics includ- Protecflor® combination (S. boulardii CNCM weeks compared to control (93.3% vs. 81.8%, p ing inulin and FOS, or with minerals and vitamins. I-1079, L. helveticus Rosell®-52, L. rhamonosus <0.05). The product also decreased the incidence The company also works on the development of Rosell®-11, and B. longum Rosell®-175) of adverse effects vs. control (17.7% vs. 28.6%). product containing the live microorganism yeast Protecflor® combination has been docu- S. boulardii combined with derivatives yeast cell mented in two studies. In an in vivo model (Bissons S.boulardii CNCM I-1079 and three Rosell® extract to provide yeast-based products. 2009), the author evaluated the effect of the bacteria strains (same bacteria strains as product on traveler’s diarrhea (TD) induced by Protecflor®, but with different NEW AREAS OF RESEARCH E. coli ETEC on rats. The infected rats were split into concentration and ratio) Fostering an open culture of innovation four groups administrated with S. boulardii CNCM Two randomized controlled clinical studies and excellence I-1079 alone, mix of three probiotic bacteria, were completed on infants with diarrhea induced Going beyond the traditional use of the

/ŶŇƵĞŶĐĞ ŽĨ ƚƌĞĂƚŵĞŶƚƐ ŽŶ ďŽĚLJ ǁĞŝŐŚƚ ůŽƐƐ ŽĨ ƌĂƚƐ ƐƵďŵŝƩĞĚ ƚŽ ƚŚĞ ŝŶĚƵĐƟŽŶ ŽĨ d͘ ΀ŝƐƐŽŶ ϮϬϬϵ΁

tĞŝŐŚƚ ůŽƐƐ ;ΎW с Ϭ͘ϬϮ vs͘ ƉůĂĐĞďŽͿ ^ƚŽŽů ĐŽŶƐŝƐƚĞŶĐŝĞƐ ŽĨ ƌĂƚƐ ĂŌĞƌ ƚŚĞ ŝŶĚƵĐƟŽŶ ŽĨ d͘ ΀ŝƐƐŽŶ ϮϬϬϵ΁ 10

0 'ƌŽƵƉ ŽŶƚƌŽů WůĂĐĞďŽ Dŝdž ŽĨ ƉƌŽďŝŽƟĐ ďĂĐƚĞƌŝĂ S. Boulardii WƌŽƚĞĐŇŽƌΠ

ĂLJ ϭϰ ;ŝŶĚƵĐƟŽŶ E. coli) ,ĂƌĚ ŝĂƌƌŚĞĂ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ,ĂƌĚ ĂŶĚ ƐŽŌ No -10 ĂLJ ϭϱ ,ĂƌĚ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ,ĂƌĚ ĂŶĚ ƐŽŌ ĚŝĂƌƌŚĞĂ ŽďƐĞƌǀĞĚ Gram -20 ĂLJ ϭϲ ,ĂƌĚ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ,ĂƌĚ ĂŶĚ ƐŽŌ * ĂLJ ϭϳ ,ĂƌĚ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ,ĂƌĚ ĂŶĚ ƐŽŌ ŝĂƌƌŚĞĂ ĂŶĚ ƐŽŌ ,ĂƌĚ -30 EŽƌŵĂůŝnjĞ ŝŶ ϯ ĚĂLJƐ &ĂĞĐĞƐ ŽďƐĞƌǀĂƟŽŶ ĂŌĞƌ ŝŶĚƵĐƟŽŶ ŽĨ E. coli: -40 &ĂĞĐĞƐ ĂƌĞ ŶŽƌŵĂůŝnjĞĚ ĂŌĞƌ ƚŚƌĞĞ ĚĂLJƐ ĂŶĚ ŶŽ ĚŝĂƌƌŚĞĂ ŽďƐĞƌǀĞĚ ŝŶ WƌŽƚĞĐŇŽƌΠ ŐƌŽƵƉ Control Placebo Protecflor® S. boulardii Mix bacteria

A. Influence of treatments on body weight loss of rats submitted to the induction of TD. B. Stool consistencies of rats after the induction of TD.

Figure 3:

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probiotic yeast to address gut health conditions, pilot study: 11 healthy adults with elevated levels segments, through an integrated research Saccharomyces boulardii CNCM I-1079 is recom- of cholesterol have been recruited to participate platform from in vitro and in vivo models to mended in novel areas of research to develop in this trial and were administrated S. boulardii clinical studies. probiotic yeast application including skin health twice daily for eight weeks [Ryan 2015]. The As a complete probiotic solution provider and and metabolism. analyze of several parameters in the serum at keen on answering most innovative formula, baseline, after four weeks and after eight weeks, Lallemand Health Solutions delivers specific Skin health showed that the remnant lipoprotein particles customized solutions thanks to its technical There is a strong connexion between gut P (RLP-P) significantly decreased by 15.5%, over expertise in formulation and delivering formats. health and skin health: an unbalanced microflora the eight-week period (p = 0.03), while taking can lead to a leaky gut, thus setting up a pro- S. boulardii. Low level of RLP-P being a biomarker Expert through the entire value chain inflammatory environment, resulting in inflamma- for good cardiovascular health. As an expert in the yeast production since tion, oxidative stress burden, sebum excess or 1923, Lallemand Health Solutions proposes atopic lesions. Therefore, S. boulardii showed LALLEMAND HEALTH SOLUTIONS the well-known and unique probiotic yeast promising results for imperfect skin such as acne Quality probiotics. Complete solutions. Saccharomyces cerevisiae var. boulardii CNCM with three mechanisms of action involved in the Lallemand Health Solutions is a vertically I-1079 registered at the Collection Nationale de skin-gut axis and two clinical studies performed on integrated probiotic manufacturer specializing in Cultures de Microorganismes. From the fermenta- adults with acne vulgaris revealing benefits of a the research, development, and manufacturing of tion process through to finished product stability treatment with the probiotic yeast. ready-to-market and custom probiotic formula- control and continuous customer support, tions. Its products target specific populations and Lallemand Health Solutions has the full control and Metabolism health segments, including gut health, natural expertise to provide a wide range of S. boulardii- Saccharomyces boulardii CNCM I-1079 has also defenses, babies’ health, women’s health, brain- based solutions, blends and custom formulations, been studied in the field of metabolism through a gut axis, skin health, metabolism, oral health, and meeting the highest quality standards throughout

Figure 4: Value chain main steps

Research and Customer Fermentation Formulation Dosage forms Logistics Development Support

• In-house yeast culture • 100 years in yeast • Grinding • ZĂǁ ŵĂƚĞƌŝĂůƐ͕ ƐĞŵŝͲĮŶŝƐŚĞĚͬ • &ŝŶĂů ƉĂĐŬĂŐŝŶŐ ŽƌŐĂŶŝnjĂƟŽŶ͗ • Sales ĐŽůůĞĐƟŽŶ ƉƌŽĚƵĐƟŽŶ ĮŶŝƐŚĞĚ ƉƌŽĚƵĐƚƐ cardboard, labelling, • Blending ƉĂůůĞƟnjĂƟŽŶ • dĞĐŚŶŝĐĂů ĂŶĚ ŵĂƌŬĞƟŶŐ • ^ĐŝĞŶƟĮĐ ĞǀŝĚĞŶĐĞ • 'DWͲĐĞƌƟĮĞĚ ƉůĂŶƚ • Powders, capsules, sachets support ƐƵƉƉŽƌƟŶŐ >ĂůůĞŵĂŶĚ͛Ɛ • ůĞĂŶ ĨŽƌŵƵůĂ ĂŶĚ ƐƟĐŬƐ • >ŽŐŝƐƟĐƐ ĐŽŽƌĚŝŶĂƟŽŶ proprietary strain, • ŽŶƚƌŽů ŽĨ ĞĂĐŚ ƐƚĞƉ ŽĨ ƚŚĞ • Regulatory support • ŽŵďŝŶĂƟŽŶ ǁŝƚŚ ďĂĐƚĞƌŝĂ • ůŝƐƚĞƌƐ͕ ďŽƩůĞƐ͕ ďŽdžĞƐ S. boulardii CNCM I-1079 ŵĂŶƵĨĂĐƚƵƌŝŶŐ ƉƌŽĐĞƐƐ • WƌĞƉĂƌĂƟŽŶ ŽĨ ƐŚŝƉƉŝŶŐ ĂŶĚ ƉŽǁĞƌĨƵů ŝŶŐƌĞĚŝĞŶƚƐ ĚŽĐƵŵĞŶƚĂƟŽŶ • ^ĐŝĞŶƟĮĐ ƐƵƉƉŽƌƚ • In-house stability program • WƌŽǀĞŶ ƐLJŶĞƌŐLJ ŽĨ ƉƌŽďŝŽƟĐ • Soluble or orodispersible yeast and bacteria ĨŽƌŵƵůĂ ĐŽŵďŝŶĂƟŽŶ

Figure 4: Value chain main steps sport. Probiotics are produced in cutting-edge all production phases. plants certified to the highest quality standards. More than 600 probiotic formulas are currently S. BOULARDII PURE Promising results on acute stress-related marketed in over 60 countries across five Leveraging the singular benefits of a intestinal dysmotility continents. From lab to shelf, Lallemand Health time-tested active ingredient In 2016, West achieved an in vivo study on Solutions has the full control and expertise to PURE OFFER: S. boulardii by Lallemand is mice with intestinal dysmotility due to acute produce premium probiotic solutions, blends, and offered as the only active ingredient, focusing on stress. After the administration of S. boulardii custom formulations, as each development step its outstanding benefits. It is available as CNCM I-1079 or its supernatant in jejunal and is expertly supported by internal quality insurance, rod-shaped powder committed to the highest colonic tissues, the author showed that the regulatory affairs, research and development, standard of pharmaceutical grade or as ground probiotic yeast reversed the effects of stress scientific affairs, technical support, and sales and powder as food supplement ingredient with three- on both the small and the large intestines, marketing teams. year shelf-life. Lallemand Health Solutions also returning them to unstressed levels through Research and development has always been a offers semi-finished or finished products and significant restoration of velocity (p <0.001) fundamental value. Applying leading-edge tech- provides an exclusive solution: the 100% and significant regulation of frequency nologies and innovative scientific approaches S. boulardii clean-label capsules. Manufactured (p <0.005). S. boulardii supernatants also Lallemand Health Solutions R&D team studies the with the high-quality S. boulardii powder in an indicated a beneficial effect on intestinal human microbiome and how probiotic supple- excipient-free vegetable transparent capsule. No motility. ments can be used as a mean to improve or other ingredient, only pure S. boulardii as a maintain health in specific populations or health naturally different probiotic yeast product. Two

PowdersPowders ClClean-labeleanean-lab label StandardStandard SelectedSelected SachetsSachets capsulescapsules capsulesccapsules packagingg andands sticksticks

Figure 5: S. boulardii Pure offer

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REFERENCES: sizes are available depending on consumer habits Protecflor® Audy, 2012. Transcriptomic response of immune signaling pathways in intestinal and market preferences: size 1 with 5B CFU/caps Protecflor® combines S. boulardii CNCM epithelial cells exposed to lipopolysaccharides, Gram-negative bacteria or potentially probiotic microbes. Beneficial Microbes, 3(4): 273-286. Bisson, 2009. or size 0 with 10B CFU/caps, in specific packaging, I-1079, L. helveticus Rosell®-52, L. rhamnosus Preventive effects of different probiotic formulations on travelers’ diarrhea model in all selected by the in-house stability programs Rosell®-11, and B. longum Rosell®-175 and has wistar rats. Dig Dis Sci. Apr; 55(4):911-9. Gaisawat, 2019. Probiotic Supplemen- tation is Associated with Increased Antioxidant Capacity and Copper Chelation in ensuring the optimal survival of the micro-organ- been studied in literature. It demonstrated a C. difficile-Infected Fecal Water. Nutrients 2019, 11(9), 2007. Gaisawat, 2020. ism. synergistic effect and benefits in a clinical study Probiotic Supplementation in a Clostridium difficile-Infected Gastrointestinal Model Is Associated with Restoring Metabolic Function of Microbiota. Microorganisms 2020, To ensure both the yeast survival during the performed in adults with Helicobacter pylori. 8(1), 60. Grandy, 2010. Probiotics in the treatment of acute rotavirus diarrhea. A complete shelf-life as well as a delivery format randomized, double-blind, controlled trial using two different probiotic preparations suitable for babies and children, Lallemand Health Active adult gut defenses 2.0 in Bolivian children. BMC Infectious Diseases, 10:253. Grgov, 2016. Can probiotics improve efficiency and safety profile of triple Helicobacter pylori eradication Solutions proposes S. boulardii-based solutions in A combination of highly documented therapy? A prospective randomized study. Vojnosanit Pregl. 73(11): 1044–1049. sachet and stick, soluble formula with or without yeast and bacteria (S. boulardii CNCM I-1079, Kelesidis, 2012. Efficacy and safety of the probiotic Saccharomyces boulardii for the prevention and therapy of gastrointestinal disorders. Therapeutic Advances in flavours or orodispersible with sweetener and L. rhamnosus GG and two other probiotic bacteria Gastroenterology, 5(2) 111-125. McFarland, 2010. Systematic review and meta- yummy flavours whilst reaching the highest strains) is offer for active adult. analysis of Saccharomyces boulardii in adult patients. World J Gastroenterology, 16(18): 2202-2222. Moens, 2019. Lactobacillus rhamnosus GG and quality standards to manufacture probiotics Saccharomyces cerevisiae boulardii exert synergistic antipathogenic activity in vitro solutions for this specific population. Adult gut defenses 2.0 against enterotoxigenic Escherichia coli. Beneficial Microbes. 10(8): 923-935. Pais, “Following the “clean-label” trend, where less Also offer, adult gut defenses 2.0 formulated 2020. Saccharomyces boulardii: What Makes It Tick as Successful Probiotic? Journal of Fungi, 6(2), 78. Ryan, 2015. Effect of the Probiotic Saccharomyces is best, Lallemand Health Solutions provides a with S. boulardii CNCM I-1079, L. rhamnosus GG boulardii on Cholesterol and Lipoprotein Particles in Hypercholesterolemic Adults:A simple and pure solution leveraging the singular and the prebiotic inulin, a source of fiber for Single-Arm, Open-Label Pilot Study.The Journal of Alternative and Complementary Medicine. 21(5): 288-293. Teran, 2009. Nitazoxanide vs. probiotics for the benefits of a time-tested active ingredient”, notes bacteria. treatment of acute rotavirus diarrhea in children: a randomized, single-blind, Romane Maillet, Product Manager and yeast controlled trial in Bolivian children. International Journal of Infectious Diseases. 13: 518-523. West, 2016. Effects of Saccharomyces cerevisiae or boulardii yeasts on product specialist, at Lallemand Health Solutions. Innovative products to meet acute stress induced intestinal dysmotility. World J Gastroenterol. 28; 22(48): specific needs 10532–10544. S. BOULARDII INSIDE “Lallemand Health Solutions supplies An expertise in formulation with bacteria traditional raw material and turnkey solutions with strains and with other powerful ingredients to various range of premium products, split in two procure synergistic effects. dedicated offers: PURE and INSIDE. Encouraging On top of its expertise in yeast production, innovation, it can also develop unique and tailored- Lallemand Health Solutions is also a pioneer in made formulation and mix”. Concludes Romane probiotic bacteria offering a large range of Maillet. in-house bacteria-based solutions targeting Find out more at sboulardiibylallemand.com different health segment and specific population. or for more information, please contact Therefore, Lallemand Health Solutions provides [email protected] exclusive ready-to-use solutions of yeast, bacteria and other powerful ingredients to meet all needs.

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Save the date:

NutrEvent, the European meeting place for innovation in Food, Feed, Nutrition and Health, comes back for its seventh edition in Lille!

s the European leading partnering event dedicated to innovation in Food, Feed, Nutrition and Health, NutrEvent aims at identifying industrial, scientific, commercial and financial partners for R&D projects and innovations. In the unique context of this year, the NutrEvent’ seventh edition will be organised together with AgeingFit (the European partnering event fostering innovation in the Healthy Ageing sector) at the same dates and place: January 26th and 27th, 2021 in Lille. For more information about AgeingFit, please visit www.ageingfit-event.com NutrEvent gathers more than 600 interna- tional actors from over 20 countries: ingredient suppliers and distributors, finished food product and food supplement industries, academic stakeholders, technology transfer organisations, research institutes, R&D services and consulting firms and investors. © Vincent Eschmann NutrEvent fosters the dynamic between exhibition area. industry and academic stakeholders, and contin- Exhibition ues its trajectory towards becoming the leading Conferences and roundtable discussions Ideally located at the focal point of the event, European event in nutrition & health innovation. Steered by a prestigious international the exhibition area increases the networking NutrEvent’s position as the key platform for new Committee, NutrEvent offers a broad programme opportunities and puts the spotlight on your R&D and innovation partnering opportunities has dealing with the market trends in the Nutrition and expertise and values. steadily developed since 2009. Its goal is to Health sectors, the recent regulatory evolutions, contribute to innovative product and service the best practices to collaborate, the sources of development in the agri-food, health and nutrition funding for R&D and innovation projects. Since industries. 2019, NutrEvent also includes a track of confer- The event features: one-to-one meetings, ences devoted to innovation between the Food More information: www.nutrevent.com conferences and roundtable discussions, pitch and Feed sectors. Event Venue: sessions and exhibition. Lille Grand Palais Pitch sessions 1, boulevard des Cités Unies One-to-one meetings The NutrEvent pitch sessions are a great 59777 Lille, France The business convention is the most efficient opportunity for young companies (and particularly Key numbers of NutrEvent last edition: way to identify and connect with potential start-ups seeking to raise a financing round) to - 600+ delegates business/research partners and investors involved showcase their project in front of potential - 20+ countries represented in the Food, Feed, Nutrition and Health sectors. partners and investors in the Food, Feed, Nutrition - 65 high-level speakers Thanks to a highly efficient and user-friendly and Health sectors. - 2,500+ meetings generated platform available one month before the event, The selected candidates will be offered to the participants can identify and send meeting present their project and receive advice and Contact: requests to other participants of their choice. The feedback (“speed-mentoring”) from a panel of Frida Heukane partnering platform enables NutrEvent’s partici- experts. Business Development Manager pants to pre-qualify up to 30 meetings over both The winner(s) will be awarded as the most Email: [email protected] days. The attendees can also organise their innovative project(s) in Europe in Food, Feed, Tel:+33 (0) 359 390 186 meetings at their own stand in the heart of the Nutrition and Health.

62 Innovations in Food Technology | August 2020 | www.innovationsfood.com NUTREVENT:TESTING 12/8/20 16:45 Page 3

More than just Tableting

Benefits of DC Minerals

X Excellent flowing behavior X Dust reduced quality X Homogenous particle structure X Direct compressible for easy tableting SABINSA:TESTING 12/8/20 17:25 Page 2

Sabinsa earns non-GMO project verification for eleven key ingredients

abinsa is pleased to announce that providing consumers with the non-GMO choices. several of the company’s ingredients With numerous Verified products available, Sabinsa have been Non-GMO Project Verified, is a valuable part of our non-GMO future,” said adding to the value the end-user Hans Eisenbeis, Director of Marketing and finds in Sabinsa’s transparency and Communications. commitment to natural, sustainable, and Non-GMO For more information please visit: ingredients. sabinsa.com/nongmo “Providing health conscious consumers with herbal, probiotic, and digestive enzymes products that support their preference for Non-GMO Sabinsa's key ingredients earning Non-GMO ingredients can be challenging, so going this extra Project Verified certification include: step in transparency is one way we can support our • Boswellin® Super Boswellia (Boswellia serrata) About Sabinsa manufacturing and brand owner partners, retail- Extract Sabinsa, founded in 1988 by Dr. Muhammed Majeed, is a ers, and their customers,” said Shaheen Majeed, • Curcumin C3 Complex® Turmeric (Curcuma manufacturer and supplier of herbal extracts, cosmeceuticals, Sabinsa’s President Worldwide. “The credibility the longa) Extract probiotics, minerals, and specialty fine chemicals. The Non-GMO Project Verified seal brings is an impor- • Shagandha® Root Extract 2.5 % USP (Withania company markets over 100 standardized botanical extracts tant addition to demonstrating Sabinsa’s integrity.” somnifera) and employs more than 1000 people worldwide in 12 The Non-GMO Project Verified is North • Livinol® Kokum (Garcinia indica) Extract manufacturing, R&D, sales, and distribution facilities. Process America’s leading independent third-party verifi- • Saberry® Amla (Emblica officinalis) Extract development and product innovation form the focus of the cation for products that are produced according • Cococin™ Coconut (Cocos nucifera) Water Solids ongoing R&D efforts in the company’s research facilities, to best practices in avoiding Genetically Modified • BioPerine® Black Pepper (Piper nigrum) Extract located in India and the U.S. Products, many of which are both Organisms (GMO). Products bearing the Non-GMO • LactoSpore® Bacillus coagulans MTCC 5856 Kosher and Halal, are extensively researched, patented, and Project Verified seal have gone through a Probiotic in three grades: 6B, 15B, and 100B supported by hundreds of published clinical studies. Sabinsa’s comprehensive evaluation process according to a • DigeZyme® proprietary, versatile multi-enzyme botanical cultivation program totals nearly 40,000 acres to consensus-based rigorous standard, which includes complex ensure sustainable, fair trade materials are used in these traceability, segregation, and meaningful, ongoing “The Non-GMO Project applauds Sabinsa’s ingredients. For more information, visit www.sabinsa.com. testing of high GMO risk ingredients. commitment to transparency in the marketplace,

Curcumin cultivation / Curcumin C3 Complex® © Sabinsa Corporation CFF:TESTING 12/8/20 16:05 Page 3

Clean label dietary shakes with SANACEL® add 045

he meal preparation is relocating from the private person to the industry but the nutritional aware- ness of the population is still rising. The people want to buy ready-to- eat food but it should be healthy and free of “unknown” additives. The list of ingredients should be short and the consumer want to avoid E-numbers if possible. To give the consumers a better overview about the ingredients, the producer is allowed to claim their product as “clean label” if it is free of additives like artificial flavours, colours, allergens, aromas, sugar etc.. They are allowed to write claims like “free of….” or “with- out…” on the package if the product fulfills the requirements and if it is no advertisement with a matter of course. Since this topic is more and more common, the producer is strive to replace their additives with natural alternatives. The dietary fibre intake of western people is far too low. At the homepage of the “British Nutrition Foundation” it is written, that the average consumption is about 18 g per day instead of 30 g, which is recommended by the WHO. This deficit is mainly caused by the development of the food industry towards ready meals and junk food. People rarely buy fresh ingredients to prepare their meal by themselves, instead they buy ready-to-eat food to save time and be more flexible. The high processed food often contains low levels of nutrients like dietary fibre. Without adding extra fibre to the products the average dietary fibre intake of the population will hardly meet the recommended daily intake. Many people still don’t know the health benefits connected with dietary fibre and the disadvantages that can be caused by fibre deficiency. Dietary fibre helps our digestive system to stay healthy by stimulating the bowel move- ment. Thus the transit time of the bolus through the colon is reduced and the shortened contact time helps to prevent the bowel wall from harm- ful substances like carcinogens. Most of the dietary fibre have a prebiotic impact. The intestinal mucosa protecting bacteria can ferment the fibre reduction of cholesterol in blood and the produc- the insulin sensitivity they can regulate the blood in the gut which increase the growth of this tion of short-chain fatty acids due to the fermen- sugar level. Less insulin is needed to reduce the bacteria as they use the dietary fibre as energy tation. The production of short chain fatty acids blood sugar level after a meal, when the previous source. The body becomes protected against might be connected with the weight manage- meal was high in fibre. This effect is called “second pathogens, toxins and the leaking gut syndrome. ment. There are indications, that a high level of meal effect”. Furthermore, because of their ability This in turn supports the immune system through short chain fatty acids enhances the production of to speed up digestion, insoluble fibre can also strengthening of the intestinal wall. In reverse, if the hormone leptin, which regulates the feeling of prevent constipation. the dietary fibre uptake is too low, the bowel wall satiety. During the last years the consumption of high becomes attacked and damaged. Especially insoluble fibre have an additional protein fitness shakes has increased. They were Another positive effect of dietary fibre is the benefit on the sugar metabolism. By promoting developed to support the training or to replace a

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meal. The diet of consumers of these products often goes along with a reduction of carbohy- drates which in turn causes a reduction of dietary fibre. Some shakes contain soluble fibre but insoluble fibre is rarely to find. The issue of soluble fibre is, that in high dosages they may cause flatulence due to a quick fermentation process. In comparison, the fermentation rate of our insoluble SANACEL® fibre is much slower. So, the air will be released over a longer time and is not causing a noticeable abdominal bloating, that customers would recognize negatively. That is a big advantage for a product in order to be recognized as well tolerated. A general time span for the fermenta- tion process is not given because it is depending on the composition of anyone’s microbiome in the colon. The only challenge left for the producer is to Figure 1: Satiety with and without SANACEL stabilize the insoluble fibre in the drink and prevent the product to settle down on the bottom. There- fore we, the CFF GmbH & Co. KG, have developed a SANACEL® add blend to increase the dietary fibre content of protein shakes and dietary drinks by combining high soluble and insoluble, slow fermentable fibres. Due to this special combina- tion we created a fibre blend which do not just enrich the shake with dietary fibre but also stabilizes it and gives it a smooth mouthfeel as the soluble fibre acts like a coating around. To rate the performance of the SANACEL® add 045 a small consumer study was done by our company. The aim of this trial was to compare a fibre enriched drink with a standard drink without fibre. The study was performed as a single-blind-trial with 15 subjects. Every person had to test 2 shakes, Figure 2: Duration of satiety one enriched with fibre and one without. The trial took place at two different days at the same time in the morning. While and after consumption of the shake the subjects were asked to rate the shakes by filling out a questionnaire. Figure 1 shows, that both shakes have an effect of the satiety after consumption. The shake enriched with SANACEL® add 045 did increase the satiety slightly more compared to the same drink without SANACEL® add 045. Three hours after consumption of the shake the satiety was still noticeable. Figure 2 shows that around 25 % of the people stayed saturated for at least 3 hours after consuming a fibre enriched shake. In comparison, after intake of the shake without fibre enrichment, less than 15 % stayed sated for 3 hours. In the questionnaire it was also asked, to rate the well-being before and after consumption (Figure 3). With this small study no significant Figure 3: Well-being with and without SANACEL difference between the products could be found. Both, gastro intestinal issues during the day and product a creamy mouthfeel. By varying with the therefore increase satiety. Mattes and Rothacker also a better well-being, are lightly increased with dosage of SANACEL® add 045 different textures of reported 2001, that the consistency of a shake the fibre-enriched shake. Everyone with gastro the final product can be reached. influences the saturation effect. A thicker shake intestinal Problems after consumption of the The result, that a fibre rich diet influences the significantly increases satiety compared to a shakes said, that they usually don’t drink protein satiety of the subjects is not surprising. As mention thinner shake. shakes. Therefore it is unclear if the issues caused in the meta analyses of J. Salvin and H. Green 2007, Non-viscous functional fibre like oligosaccha- from the unfamiliar high protein intake or the two factors are mainly influencing the satiety: the rides, resistant starch and polydextrose seem to dietary fibre. A more reliable study with a larger gastric distention and the time and work invested have only little influence on satiety, even if they number of subjects, which are used to high protein for chewing. Both factors can be increased by are added in high amounts. The combination of dosages, is needed. dietary fibre. The additional bulk of the diet, caused the fibres used in our SANACEL® add 045 blend, Regarding the mouthfeel both shakes showed by fibre enrichment, reduces simultaneously the has a high thickening effect on the shake and a creamy texture. Some people described the energy density of it. In addition, the volume of the enhances the viscosity of the product, so this shake with fibre as unpleasant because of a too bolus becomes increased and the transit time supports the evidence that the increase on satiety thick mouthfeel. This causes from the fact, that through the stomach is delayed which leads to a showed in our trial is coming from the combination the SANACEL® add blend was added on top of a longer lasting feeling of satiety. Important to of soluble and insoluble dietary fibres used. marked product and can be compensated by recognize is, that not all dietary fibre have an The influence of insoluble cellulose fibre on adaptation of the recipe. That means, other influence on the satiety. Mostly viscose fibre, even satiety was tested by Astrup et al. (1990). 22 obese thickening agents in the product can be replaced in small dosages, increase satiety. A soluble fibre individuals consumed a very-low-energy-density by a natural clean label ingredient which gives the like psyllium has a high thickening character and diet either enrich with fibre or without. After the

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trial, only the group without fibre enrichment reported increased feelings of hunger. They also determined an increased bowel movement after Visitour new the fibre rich diet without effecting flatulence. An impact on the absorption of divalent cations such NEWS website as calcium, magnesium or iron could also not be determined. Due to the connections between dietary fibre www.cff.de www.innovationsfood.com and satiety it is obvious, to use fibre in dietary food against obesity. SANACEL® add 045 combines viscosity increasing fibres with insoluble fibres, which increases the satiety after food uptake, by * Online magazine reducing the gastric emptying. About CFF SANACEL® add 045 is the perfect alternative Located in Germany and founded in 1977 CFF GmbH & Co. • Features to combine the health benefits given by the fibre KG distributes dietary fibers from Gehren and Temse, Belgium • Daily news with their technological benefits. The shake into more than 70 countries around the world. As a producer • Study news becomes enriched with dietary fibre without a high of food ingredients, it is very important for CFF to offer high carbohydrate intake. Our blend exclusively contains quality technical support, customized fiber solutions and an • Productlaunches natural ingredient and can be used in clean label innovative growing portfolio. Experts can give the appropriate • Event dates products without E-numbers. recommendation for each of your specific applications, please The properties of the SANACEL® add 045 are: feel free to be in touch. • neutral in colour (off-white), taste and odour For 40 years CFF is motivated by the remarkable Send your news to Terry Prior • allergen free application diversity of cellulose fibre. Then and now it is the [email protected] • E-Number free, clean label engine for the development and manufacturing of the • can be easily mixed with other powdery functional fibre products TOPCEL®, TECHNOCEL®, DIACEL®, or ingredients SANACEL®, SENSOCEL® & QUALICEL®. Fromnatural and David Copperfield at biodegradable raw materials CFF produces eco-friendly davidcopperfield@innovations- Author: products which remain integrated into the natural cycle – from Sabrina Siegmund nature – back to nature. food.com Product Manager Food International

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Free From Functional & Health Ingredients North Edition is returning to Amsterdam! 24th-25th November 2020

ree From Functional & Health others are expecting. Together we can start to fire be a uniting force - bringing together the world’s Ingredients, Europe’s leading up the economic engine of the food industry in a most eminent food and drink professionals. Over innovation platform for the free safe and secure way! two days, the event will showcase the latest trend from, organic, vegan, functional To reflect this dynamic and rapidly evolving predictions, market analysis, whilst delivering and ingredient food industries market, this year, the event will showcase a wide extensive networking opportunities and unveiling returns to Amsterdam for its North Edition. The 8th range of new features to meet the needs of its the latest product innovations across five core edition of the exhibition will be held at RAI increasing number of high caliber visitors. categories. Amsterdam on 24th – 25th November 2020. Today, free from encompasses an ever- International trade buyers, producers, manu- Together with local event venues and the growing range of dietary requirements and is a facturers, and key global industry figures are Dutch government we are developing safety powerful performer within numerous retail expected over the two days in Amsterdam to take protocols for the Free From Functional & Health categories – from snacking, ready meals and advantage of new trends and opportunities in this Ingredients Expo. Our main priority is to secure the out-of-home, to frozen, confectionery and vibrant and established market. safety of all attendees and to establish an expo everyday grocery essentials. All of which will be that can be joined with confidence and security. represented by pioneering international brands For more information and to receive the latest So we trust that we will organize the successful and a packed conference schedule. updates or register yourself, please visit expo that many of you are accustomed to and The successful trading platform continues to www.freefromfoodexpo.com.

Plant based yogurt market well positioned to overtake dairy based yogurts, changingg dietary preferences among consumers driving growth – Future Market Insights

Initially a niche market, plant-based yogurts have now acquired a consolidated presence in the food & beverages market. As consumers increasingly realize the importance of good health, their consumption of vegetarian products has soared, prompting market players toundertake significant investments tofulfill this demand

uture Market Insights: The global plant consumption of immunity boosting foods amongst among market players to satiate these sensory based yogurt market is anticipated consumers. With the pandemic ushering in a high experiences," concludes a leading FMI analyst. to demonstrate strong growth degree of uncertainty regarding the safety of Request a report sample consisting of 250 prospects during the forecast period consuming animal-derived dairy products, pages to gain in-depth market insights on 2020-2030, registering a double-digit consumers are transitioning towards plant-based https://www.futuremarketinsights.com/reports/sa CAGR. As the proportion of flexitarian and vegan yogurt as a precautionary measure. mple/rep-gb-11684 population increases, demand for plant-based Moreover, declining dairy production due to foods is riding the high wave. Plant-based yogurts reduced agricultural activity amid social distancing Plant based yogurt market - are considered more environmentally sustainable protocols have generated a demand-supply gap in key takeaways compared to dairy-based yogurts. mainstream dairy products, clearing the pathway Strawberry flavored yogurts shall remain High nutritional value associated with plant- for plant-based yogurt manufacturers to establish favored among all other flavours of the plant-based based yogurts is a key driving factor behind the their supremacy in the yogurt market. Additionally, yogurt market during the forecast period. proliferation of the plant-based yogurt market. prevalence of lactose intolerance amongst Organic plant-based yogurts shall tower over Incidentally, consumers are increasingly seeking consumers is encouraging higher consumption of conventional ones, attributed to adoption of novelties in yogurt flavours and indulge their plant-based yogurts. healthier lifestyles and consequent increase on sensory experiences. This has prompted market "Consumer preferences for conventional spending for functional foods. players to invest in product innovations and flavours is eroding at a rapid pace. Their willingness Nut-based yogurts dominated the market dur- experimentation with different flavors, thereby a to experiment with different flavour combinations ing the historical period, capturing over half of the ccelerating market growth. have generated a dynamic pattern in the plant- plant-based yogurt market. The COVID-19 pandemic has heightened the based yogurt market, inspiring innovations Increased concern for animal welfare is prompt-

68 Innovations in Food Technology | August 2020 | www.innovationsfood.com FREE FROM FEATURE:TESTING 12/8/20 16:18 Page 3

ing consumers to shift towards plant-based yogurt consumption. North America and Europe shall remain the most lucrative markets for the sales of plant-based yogurts. Entry of various market players by virtue of partnerships and acquisitions is anticipated to keep the demand high in these regions.

Plant based yogurt market - key driving factors  129(0%(5 2020 - AMSTERDAM One-third of the North American people have curtailed their meat and dairy intake, bolstering demand for plant-based products. This trend has ages. It is a common belief among medical launches and strategic collaborations in order to created optimum conditions for the plant-based practitioners and individuals that a healthy diet acquire a competitive edge. As the number of yogurt market to flourish. would help the body develop adequate strength to collaborations and acquisitions gather momentum A burgeoning retail industry by virtue of fight the infection. As a result, consumption of in the coming years, the plant-based yogurt several technological advancements are enhanc- plant-based foods has seen a staggering increase. market shall expand at an impressive pace. ing the shopping experiences of consumers. In Owing to calls for maintaining social distanc- Additionally, a consumer-oriented approach is addition, attractive packaging and flavour combi- ing, leading market players are effectively exploit- assisting players in greater market penetration. This nations are compelling consumers to purchase ing the e-commerce channel in order to expand includes introduction of exotic flavours to indulge plant-based yogurts, driving market growth. their sales. With the availability of a myriad range of consumers' tastes and improving their confidence. The trend of product positioning with flavors on online sales channels, consumers are additional functional claims such as high protein presented with an array of choices to select from Get valuable insights into plant-based and probiotic content is deepening plant-based within the comfort of their homes. Co-incidentally, yogurt market yogurt market penetration in countries such as traditional retail sales of plant-based yogurts has Future Market Insights, in its new report, Brazil, India, Poland and China. experienced a resurgence as several countries presents an unbiased analysis of the global plant- across the world have relaxed the curbs imposed based yogurt market, covering historical demand Plant based yogurt market - on netizens, enabling them to visit departmental data and forecast figures for the period between key constraints stores and supermarkets to purchase their 2020 and 2030. The study divulges compelling Misperceptions about the presence of lower products. insights into growth witnessed in the market. nutritional content in plant-based yogurts Explore the plant based yogurt market report Based on nature the market can be segmented compared to milk-based yogurts among develop- comprising 160 illustrative figures, 192 data tables into conventional and organic. In terms of flavour, ing nations is limiting market penetration. and the table of contents. You can also find a the market can be segmented into regular, vanilla, High price volatility in comparison to its milk- detailed market segmentation on https://www. strawberry, blueberry, cherry, peach, raspberry, based alternatives is impeding the expansion of futuremarketinsights.com/askus/rep-gb-11684 coconut, coffee, and others. Based on product plant-based yogurt markets across regions. type the market can be segmented into cereal Competition insights type, legume, nut, seed, and pseudo cereal. Based Anticipated impact of the coronavirus The plant based yogurt market is extremely on price range the market can be segmented into outbreak competitive, characterized by the presence of over economic, mid-range, and premium. Based on COVID-19 has ushered in an era of unprece- 100 market players. Prominent players operating sales channel the market can be segmented into dented uncertainty. As countries struggle to in the plant-based yogurt market include, but are food service and retail. Regionally, the market eliminate this deadly disease by imposing lock- not limited to: Lyrical Foods, Inc., Stonyfield Farm, covers North America, Latin America, Europe, East downs and social distancing measures, consumers Inc., Trader Joe's, Callifia, Chobani, Forager, Good Asia, South Asia, Oceania and MEA. are taking the initiative to adhere to basic precau- Plants, Good Karma, General Mills, Inc., Nancy's, So Read more: http://www.digitaljournal.com/ tionary steps, such as maintaining hygiene through Delicious, Silk, Danone S.A, GT's Living Foods, The regular handwashing and sanitization and also Coconut Collaborative and COYO Pty Ltd. The consuming immunity boosting foods and bever- abovementioned market players invest in product

About Food & Beverages division of FMI Expert analysis, actionable insights, and strategic recommen- dations - the Food & Beverages team at FMI helps clients from all over the globe with their unique business intelligence needs. Witha repertoire of over 1,000 reports and 1 million+ data points, the team has analyzed the food & beverage industry lucidly in 100+ countries for over a decade. The team provides end-to-end research of the global food & beverage market and consulting services; know how we can help.

About Future Market Insights (FMI) Future Market Insights (FMI) is a leading provider of market intelligence and consulting services, serving clients in over 150 countries. FMI is headquartered in London, the global financial capital, and has delivery centers in the U.S. and India. FMI's latest market research reports and industry analysis help businesses navigate challenges and take critical decisions with confidence and clarity amidst breakneck competition. Our customized and syndicated market researchreports deliver actionable insights that drive sustainable growth. A team of expert-led analysts at FMI continuously track emerging trends and events in a broad range of industries to ensure that our clients prepare for the evolving needs of their consumers.

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Why is everyone going vegan?

Dr. Justine Butler, Senior Research and Writer, Viva! Health

hat if there was a diet that the cocktail of animal hormones and growth Add to that BSE, the horsemeat scandal, bird flu could help protect you from factors found in cow’s milk and which are linked to and E. coli 0157 and it’s a wonder anyone risks chronic disease, meant that you a wide range of illnesses and diseases, from acne to eating animals foods! could still have the occasional osteoporosis. The plant-based milk market is Scientists say that the coronavirus pandemic cake, chocolate or creamy booming, offering consumers a choice made from arose from our hunger for meat, coupled to the sauce without worrying about your weight and was soya, oats, almonds, hemp, rice, coconuts or even reckless destruction of nature. Factory farms are kind to animals and the planet? There is – a vegan peas! breeding grounds for emerging zoonotic diseases diet! that jump from animals to humans. If ever A well-planned vegan diet can there was a time for the world to go provide all the nutrients you need for all vegan – it’s now! stages of life, including pregnancy, Contrary to popular belief, we are lactation, infancy, childhood, adolescence not designed to eat meat; our ancient and for athletes too. Rich in fruit and ancestors relied far more heavily on plant vegetables, wholegrain foods, pulses proteins than previously thought. Studies (peas, beans and lentils), nuts and seeds, show they ate roasted vegetables similar you’ll get all the protein, fat, carbohy- to yams and leafy vegetables, celery, figs, drate, vitamins and minerals you need, nuts, seeds and chenopodium seeds, while avoiding high levels of unhealthy which are similar to quinoa. saturated fat as well as animal protein, Compared to meat-eaters, vegans cholesterol and hormones – all linked to weigh less, have lower cholesterol, blood disease. pressure and rates of type 2 diabetes. Everyone needs a good source of They have a 30% lower risk of heart vitamin B12, for vegans, this means disease and lower cancer rates too. Given fortified foods or a supplement. Many that animal agriculture lies at the heart of plant-based milks, meats, cheese, all the world’s environmental problems, yoghurts and desserts are now fortified including deforestation, water use, with B12. The popular vegan standby, biodiversity loss and the climate crisis, nutritional yeast – known to vegans as going vegan offers enormous benefits nooch – which adds a cheesy/nutty for human health but could also help flavour to foods, can be bought with save the planet from an environmental added vitamins B12 and D. catastrophe. As the vegan movement grows, so Antioxidants Fish-free fish fingers and fish steaks provide a does the amazing abundance of foods suitable for Antioxidants help protect us from disease and fishy flavour without exposing you to the toxins vegans. There has never been a better time to go are found naturally in abundance in plant foods – and pollutants found in fish (PCBs, dioxins and vegan! especially brightly coloured fruit and veg such as mercury). You can add a taste of the ocean by Viva!Health is a part of the charity Viva!, sweet potato, carrots, red peppers, purple sprout- sprinkling some edible seaweed into dishes – you’ll Europe’s largest vegan campaign group. We ing broccoli, red cabbage, asparagus, curly kale, also get some iodine that way. If you are looking for monitor scientific research linking diet to health berries and avocados. A study published in the omega-3 fats, you can find plenty in ground and provide accurate information on which you Nutrition Journal looked at the antioxidant content flaxseed and hempseed and the oils made from can make informed choices about the food you of more than 3,000 foods – drinks, spices, herbs them as well as rapeseed and walnuts – not laced eat. and supplements used worldwide – and found that with toxic pollutants and sustainable. ‘plant-based foods introduce significantly more There are several plant-based egg alternatives antioxidants into human diet than non-plant available or you can scramble your own tofu – it foods’. provides more protein gram for gram than scrambled egg and no cholesterol (in fact, no plant Meat and dairy substitutes foods contain cholesterol) and tofu is low in Plant-based meat substitutes, such as veggie fat. Add turmeric and herbs for flavour and if you sausages and burgers, often contain as much or like it eggy, a little black salt adds a whiff of more protein than their meaty equivalents but sulphur! don’t contain the harmful substances linked to certain cancers, especially bowel cancer. Grilled, Improve your health barbequed and smoked meats contain even Another advantage of the vegan diet is that higher levels of these dangerous chemicals. You you are much less likely to suffer from food are much better off putting a veggie burger or a poisoning! Most cases are caused by meat, poultry, Portobello mushroom on the BBQ! eggs, fish and dairy – over half of all chickens sold Most plant-based milks now contain a similar in the UK are contaminated with faecal matter amount of calcium as dairy milk, but don’t contain carrying the food poisoning bug campylobacter. www.vivahealth.org.uk

70 Innovations in Food Technology | August 2020 | www.innovationsfood.com The best ingredients for success from the subcontinent!

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China health authorities acknowledge L. helveticus Rosell®-52, B. infantis Rosell®-33 and B. bifidum Rosell®-71 for safeusein infant formula

allemand Health Solutions’ three efficacy of the combination of these three probiotic probiotic strains L. helveticus Rosell®-52 strains and fructo-oligosaccharides (FOS), also (R0052), B. infantis Rosell®-33 (R0033) known as Probiokid® formula, in 132, three and a and B. bifidum Rosell®-71 (R0071), have now half month-old to six month-old healthy, formula- completed the approval process by the National fed babies, scientists concluded that Probiokid® can Health Commission of the People’s Republic of play a role in gut functions in babies and help China for use in infant food. support a normal immune development. “This endorsement is a prodigious regulatory achievement given the limited number of strains Ready for infant formula market that made it to that elitist list of only 12 strains, Whether in combination or as single strains, including these three.” Commented Solange they have also been successfully notified as China gives the Henoud, Global Regulatory Affairs Director at Generally Recognized as Safe (GRAS) to the United Lallemand Health Solutions Inc. “Our team went States (US) Food and Drug Administration (FDA) for green light to whey through a complex and lengthy registration the specific use in infant formula. The two process, but the strong evidence we had on hand bifidobacteria strains, B. infantis Rosell®-33 and permeate imports for these strains, made us confident we would B. bifidum Rosell®-71, have demonstrated in vitro reach this coveted final stage.” Concluded Mrs. synergy with human milk oligosaccharides (HMO). rla Foods Ingredients has welcomed the Henoud. Lallemand Health Solutions strains and formulas news that whey permeate can now be dedicated to babies are manufactured according to exported to China for use in food and Pivotal safety studies the highest quality standards for infant formula beverage products. A randomised, double-blind, placebo- applications, opening new market opportunities in On 15 May 2020, China published an official controlled study [Manzano, 2017] confirmed the China, US and beyond. safety and quality standard for using permeate safety and tolerance of the three probiotic strains Probiokid® , the combination of L. helveticus powders in food processing – signifying that its L. helveticus Rosell®-52, B. infantis Rosell®-33 and Rosell®-52, B. infantis Rosell®-33 and B. bifidum market is ready to accept imports of the ingredient B. bifidum Rosell®-71 in 221 healthy three to twelve Rosell®-71 and FOS, is one of the most docu- with immediate effect. month-old infants. The babies were on different mented probiotic formula with 11 clinical studies in The development comes as a result of a diets – formula, mother milk or a combination of infants and young children. It has been granted the recent trade agreement between the US and both. The post-hoc analysis [De Andres, 2018] following Canadian health claims: helps to reinforce China. However, the standard applies globally, and showed how these three probiotic strains help the body’s natural defenses and participates to the permeate from any country may be exported to support a baby-specific microflora, regardless of any microflora balance in children; could promote a China provided it complies with the requirements. influencing factors. favourable gut flora and is a source of probiotics Henrik Jacob Hjortshoej, Head of Sales In a randomised, double-blind, placebo- from three months old babies, up to older Development, Food at Arla Foods Ingredients, said: controlled study [Xiao, 2019] to measure safety and children. “The opening of the Chinese market to permeate exports is highly significant for the global dairy ingredient industry. Demand for permeate is rising fast in China, just as it is across the world. We look forward to working with our customers in China to supply them with the highest quality whey Givaudan announces divestiture permeate powder for their food and beverage applications.” of processed and grated Whey permeate is a milk solid with around 80% lactose content. Used as a bulking agent, it is a highly cost-effective replacement for skimmed cheese business milk powder, lactose and sweet whey powder. In 2017, powdered permeate received a Codex ivaudan has announced that it has attractive opportunity to further build St Paul’s Alimentarius international standard. entered into an agreement to divest its customer base in ready meals, snacks and Arla Foods Ingredients is one of the world’s processed and grated cheese business processed food. In addition, St Paul will now also largest suppliers of whey permeate, with produc- to St. Paul Group, a cheese specialist with premises be able to offer a wider range of products and tion facilities in the EU and Argentina. It markets in Belgium and the Netherlands. applications.” Variolac® whey permeate, which has sweet milky “With the sale of our processed and grated The processed and grated cheese business taste, low ash content, stable mineral profile and cheese business we aim to strengthen the focus on acquired from Vika BV contributed CHF 13.5 million free-flowing powder properties over a 12-month our core business and continue to drive long-term to Givaudan’s Flavour Division sales in 2019. The shelf life. shareholder value,” said Louie D’Amico, President terms of the transaction, which has no material Permeate is increasingly being used by multi- Flavour Division, Givaudan. “We truly appreciate the impact on the Division, will not be disclosed. national brands, particularly in categories such as contributions of our processed and grated cheese Givaudan will retain the majority of the legacy chocolate and biscuits, but also in hot drinks, dairy business employees and look forward to working Vika BV business acquired in 2017 and continue to and desserts. Innova figures show that the number with the St. Paul team to ensure a successful offer cheese powder solutions, vegetable and meat of new products containing whey permeate has handover.” fonds and stocks as part of its natural dairy and more than doubled in recent years, growing from Dieter Kuijl, CEO of St. Paul Group, said: “We are savoury product portfolio. 169 in 2015 to 387 in 2019. delighted with this transaction as it represents an

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TINE sells out of Rørosmeieriet AS Lactalis ver since its inception, TINE has been the Rørosmeieriet's further development and have had owner of the Røros dairy. This week a a good dialogue about a possible sale, while at Ingredients meets majority of the dairy at Røros was sold to the same time we have been concerned with investment company Salvesen & Thams. This means conditions that reflect the value of our ownership, the needs of the TINE's entire ownership interest of 11%. which we have now achieved, Hovland says. The Røros dairy has a great history and good The Røros dairy is also positive for the future of people. We at TINE were impressed with what they eco-milk from Røros. condensed milk have achieved and are happy that we could play a We are looking forward to a new chapter in role in helping them in the start-up. Now a new Rørosmeieriet's history. This is a solution that gives market with a chapter is starting and it was natural for us to sell us many opportunities in the future, for the our share and release others, says TINE CEO Gunnar company, employees, eco farmers and the food Hovland. industry in the Røros areas. This will strengthen us reference of The Røros dairy has become a clearer competi- and provide a basis for us to take new, major steps tor in recent years, and sees the need for further forward. TINE has been important for the Røros skimmed milk investment and new energy on the owner side in dairy startup, and we look forward to continued order to continue its growth. In this connection, good cooperation with them around important several of the initiators of the sale wanted TINE to areas such as more conversion to eco, and optimal powder also contribute to selling its share, which the dairy use of eco-milk in Norway, says dairy manager Trond co-operative has placed positive on the right Vilhelm Lund, who has led the company for the past actalis Ingredients completes its offer of conditions. 12 years. skimmed milk powder with a high heat, We certainly do not want to be a brake on heat-stable (HHHS) quality. This new reference is suitable for condensed milk producers looking for a skimmed milk powder DSM sets yield standard in heat-stable for their process. The condensed milk, a dynamic mozzarella production with market driven by the Middle new cheese cultures East and Latin America oyal DSM, a global science-based ers to meet rising consumer demand for high- Consumption of company active in Nutrition, Health and quality mozzarella cheese products, while continu- evaporated milk and Sustainable Living, recently announced ing to be economically and operationally efficient,” sweetened condensed the launch of its new Delvo®Cheese CP-500 cultures said Evandro Oliveira de Souza, Business Lead for milk continues to grow for boosting the yield and resource efficiency of Cheese at DSM. “We’re committed to offering and is expected to mozzarella cheese production. Capable of achiev- unique, stand-out products that not only look and register an average ing a higher moisture content in mozzarella, the taste good, but are also better for both consumers annual growth of range increases yield by up to 1.3%, compared to and customers. For that reason, DSM is delighted 2percent from 2019 to the most commonly used Direct Vat Set (DVS) to introduce this new extension of our portfolio of 2024. This growth comes from Latin America, the culture in the US. These cultures also enable cheese- culture solutions, which will help our customers set Middle East, and to a lesser extent from Asia. Using makers to deliver products with superior taste and a new standard for yield in cheese production and fresh local milk to produce dairy products in these texture that consumers will enjoy and are ideal for deliver market-leading end products.” areas is not always easy, because of the low milk creating mozzarella cheese for pizza, offering a DSM has decades of experience in the cheese collection. That is why some producers have to use mild buttery flavour, excellent stretch and melt industry and can help cheesemakers worldwide milk powders as a substitute for liquid milk. behavior and reduced browning for an enhanced produce high-quality, great tasting cheese products eating experience. efficiently, effectively and in a sustainable way. This Skimmed milk powder HHHS, a specific The cheese industry today has experienced a is achieved through DSM’s cultures, coagulants, quality adapted to the production of sharp rise in demand for mozzarella cheese in a cheese protection and ripening solutions, condensed milk range of product formats, including shreds, slices biopreservatives and residual antibiotics tests. Lactalis Ingredients launches a new reference and cubes. The global pizza cheese market, for Alongside the Delvo®Cheese CP-500 cultures, of skimmed milk powder in its plant of Ravensburg, instance, is expected to grow at a CAGR of 5.04% DSM’s expanding portfolio of solutions for Germany. This skimmed milk powder, called HHHS, between 2020 and 20271, which will continue to mozzarella cheese includes Delvo®Cheese CP-120 is suitable for the production of evaporated and fuel demand for mozzarella in the coming years. To cultures, and Fromase® XLG and Maxiren® XDS sweetened condensed milk, as it is stable at in-can navigate this evolving commercial landscape, coagulants. This is comple-mented by DSM’s expert sterilisation temperature. producers must create tasty cheese that will retain services, including application support, process The powder is made by drying fresh a firm texture and sliceability throughout shelf life. analysis and optimization, and tailored phage pasteurised skimmed milk, which undergoes a Increasing the capacity and speed of cheese rotation management that can help brands reduce specific heat treatment. The goal of this heat treat- production is also cru-cial to safeguard the prof- production costs, improve product quality and ment is to denature the protein to obtain a heat- itability of their operations. increase fermentation consistency. DSM’s capabili- stable powder and prevent the coagulation of the Commercial testing has shown that the ties and portfolio in support of the cheese and dairy protein during the production of condensed milk. Delvo®Cheese CP-500 range enables cheesemakers industry have re-cently been further strengthened to overcome these challenges by increasing by the acquisition of specialty dairy ingredients LactalisIngredientsskimmedmilk powder moisture content, offering the fast acidification company CSK. HHHS features expected by producers and a consistent perform- For more information on how DSM’s Suitable for evaporated and sweetened ance in terms of texture — maximizing yield and Delvo®Cheese CP-500 cultures and services for condensed milk: improving the consumer pizza eating experience. cheese production can improve yield and efficiency, • heat-stable at in-can sterilisation temperature When combined with DSM’s Maxiren® XDS as well as enhance the sensory properties of • low thermophilic spores fermented chymosin coagulants, the range mozzarella cheese for pizza, visit https://www.dsm. • good solubility enhances yield further, allowing manufacturers to com/food-specialties/en_US/insights/dairy/how- • preserved dairy taste optimize raw material efficiency and achieve high can-i-get-more-from-my-mozzarella.html whey quality. www.lactalisingredients.com “It can be a complex challenge for cheesemak- Reference: 1 Fior Market Research, Global Pizza Cheese Market-2027, 2019.

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DuPont Nutrition & Biosciences drives dairy industry innovation with Chymostar™ cheese coagulant

uPont Nutrition & Biosciences has Clementina Dellomonaco, Global Product Line “In testing, we have found that Chymostar™’s announced the global launch of Manager, Dairy Enzymes, DuPont Nutrition & improved texture development and meltability set DuPont™ Danisco® Chymostar™, a new Biosciences. “This latest solution builds on our vast it apart,” said Dellomonaco. “We’re excited about milk coagulating preparation for the dairy industry expertise in cheese cultures technology and the reliability and versatility of this coagulant for that offers optimal coagulation and ripening applications know-how. And, this coupling of customers around the world looking to make a kinetics. product innovation and years of experience in wide array of dairy products.” Chymostar™ can be used for producing any industrial and specialty cheese manufacturing Chymostar™ also meets purity and thermola- type of cheese: hard, semi hard, soft, mold- elevates any single new product; our customers bility requirements for whey quality. It is inactivated ripened, low-fat and ingredient cheeses and is the receive holistic support.” in whey by standard pasteurization techniques and latest addition to DuPont’s robust dairy ingredient Chymostar™ features a number of unique is a purified product – clear of lipase and amylase portfolio — which includes proven products like benefits, including ideal curd formation and side activities. Carlina™ Animal Rennet and Marzyme® Liquid firming speed. It enables fast flavor development To learn more about Chymostar™ and Microbial Coagulants to help solve any challenge due to its balanced proteolytic profile, thus helping DuPont’s full coagulant portfolio, visit that dairy producers may face. mitigate the time and cost of maturation. Devel- https://www.dupontnutritionandbiosciences. “Chymostar™ rounds out our portfolio in oped for a wide array of global consumers, it was com/product-range/food-enzymes/dairy- coagulants so we can serve our cheese customers important to DuPont that it be preservative-free, enzymes.html. with all critical ingredients: cultures, coagulants and Kosher, halal-certified and suitable for use in lipases based on their specific needs,” said vegetarian products.

DuPont Nutrition & Biosciences introduces CHOOZIT® BC 02 to help pizza cheese makers

uPont Nutrition & Biosciences has less energy for whey drying. announced the launch of CHOOZIT® BC Pizza cheese makers had long struggled to 02, a new phage alternative for cheese achieve consumers’ preferred cheese browning makers looking to meet the increasing global colour using natural solutions, until last year’s demand for pizza cheese and meet consumers’ successful roll-out of CHOOZIT® BC 01 in the preference in terms of pizza cheese browning. European market. To date, CHOOZIT® BC 01 is in Part of the DuPont™ Danisco® portfolio of commercial use by a significant number of leading ingredients, the new culture joins CHOOZIT® BC 01 pizza cheese producers and in approval phases in as a proprietary formulation designed to assist key countries around the broader European region. cheese makers to create added value and These countries represent roughly 77% of the total flexibility for their food service customers: enabling pizza cheese produced in Europe1. them to achieve a consistent quality pizza cheese “As demand rises across the global pizza in a wide range of ovens around the world, day industry, pizza cheese makers have looked for after day. solutions to make substantial improvement on the The CHOOZIT® BC cultures offer key advan- quality and consistency of their product,” said even stronger offering to cheese producers who tages, including robust processing conditions, Annie Mornet, Global Product Manager, Cheese need to produce in industrial volumes. The cultures browning control, better flexibility for pizza baking Cultures at DuPont Nutrition & Biosciences. “We have been designed to provide the right acidifica- in oven conveyors, consistent cheese quality with introduced CHOOZIT® BC 01 last year and found tion kinetics and proteolytic features to manage no change in texture before shredding and a lower that customers are very pleased with its unique the yield and mineralization of the cheese. The risk of spoilage – all in a natural, label friendly performance. Pizza cheese makers have confirmed metabolism of the different species allows for a solution. that CHOOZIT® BC 01 gives much better browning better consumption of the sugars, especially The cultures are clean label solutions to control control for the same cheese quality, and for some galactose, throughout the process. Moreover, browning, unlike many alternatives on the market particular pizza cheese manufacturing processes CHOOZIT® BC 01 and 02 are a biodiverse and alter- that are formulated with additives. CHOOZIT® BC manufacturers have been able to use 25% less native formulation leading to a higher robustness helps pizza cheese makers meet consumer water in the pizza cheese process. and limiting the phages issues.” preferences for natural products, while using less “CHOOZIT® BC 02 takes it a step further,” she Reference: ® water in production, a lower volume of whey and continued, “with CHOOZIT BC 02 we present an 1 DuPont InternalData.

74 Innovations in Food Technology | August 2020 | www.innovationsfood.com DAIRY:TESTING 12/8/20 16:11 Page 5

New recipes for sweetened condensed milk and investment in new packaging equipment Arla Foods ndustrially produced sweetened condensed milk is one of the most important milk-based Ingredients ingredients for the food and confectionery industry, alongside milk powder and anhydrous milk launches its first fat. The major nutritional trends of recent years, such as vegetarian and vegan products, products organic ingredient with an organic label, clean label or food for certain faith groups, also place new demands on the rla Foods Ingredients has launched the ingredients that are needed. WS Warmsener first ever organic micellar casein isolate, Spezialitäten GmbH, as a specialist for sweetened helping manufacturers meet demand condensed milk, is reacting to the current market for organic, natural and functional protein prod- trends with new product varieties and packaging ucts. options. Micellar casein isolate is a new ingredient which Sweetened condensed milk (SCM) is mainly is rich in native milk proteins. It is extracted from used in the production of high-quality caramel milk using gentle processing without the addition fillings, chocolate bars, pralines, toffees, dessert of acids. The protein maintains its chemical sauces, ice cream and many other confectionery structure, allowing the creation of products that products. There it not only provides the typical are as close to nature as possible. caramel taste, but also influences the desired Arla Foods Ingredients’ new micellar casein consistency and mouthfeel of the finished product. isolate, MicelPure™, contains a minimum of 87% WS Warmsener Spezialitäten GmbH belongs to native protein. Suitable for food, functional health the Uelzena Group and is one of the largest manu- foods and active nutrition applications, it is low in facturers for SCM in Europe. The North German lactose and fat, heat-stable and taste-neutral. dairy based in Warmsen supplies the major branded several principles and criteria that must be met for In a milestone for Arla Foods Ingredients, it is companies in the confectionery industry. To further sustainable palm oil production. also the company’s first ingredient to be offered in strengthen this position, the company is expand- an organic version, made from certified organic ing its range of products for industrial customers New forms of packaging open up markets milk from Denmark. and is also investing in a new, flexible filling line for Common packaging systems for sweetened As the first ever organic micellar casein isolate bag-in-box systems to open up completely new condensed milk are sterile steel containers, drums on the market, MicelPure™ Organic meets a clear markets. and loading in tankers. Various bag-in-box systems need. Research shows that European consumers (BIB) are also becoming more and more wide- consider organic products healthier, tastier and Current food trends require new spread, such as one-way and reusable containers more nutritious, with one in three saying they product solutions with filling quantities of up to 1,000 kg or cartons would buy more organic, high-protein snacks if The major trends of recent years, such as with a capacity of up to 25 kg. And there is currently they were available. vegetarian and vegan products, products with an a strong demand for small BIBs with a capacity of 5 Barbara Jensen, Business Development organic label, clean label or food for certain faith kg or more. They are used both in the restaurant Manager at Arla Foods Ingredients, said: “When groups that for example comply with the rules for and catering trade and also for smaller require- consumers hear ‘organic’, they think healthy, halal or kosher, are increasingly in demand by ments of more artisanal processors from the sustainable and wholesome. However, a shortage today's highly informed consumers. Therefore, the confectionery, baking craft, ice-cream parlours and of natural, organic protein ingredients has demand for suitable ingredients for the develop- small speciality manufacturers, as the company has prevented many manufacturers from entering this ment and production of these new product noticed. market. MicelPure™ Organic fills the gap, allowing qualities is also growing parallel within the food and "That is why we have invested in a versatile new companies to extend their portfolios with confectionery manufacturers. filling line, so that we can react even more flexibly products that are both organic and packed with "On the one hand, we are noticing a strong to the changing packaging requirements of our high-quality protein.” increase in demand for certified varieties such as customers. It also enables us to expand our sales Research shows that “healthy” and “natural” organic and/or Fairtrade as well as Halal and Kosher. market, especially in the export of smaller packag- are the two most important characteristics for And completely new products are being added, ing units and the new product variants with consumers of food products.1 Because it is rich in such as sweetened condensed milk with the vegetable fat to the Asian market," says Claudia native protein, MicelPure™ also helps manufactur- addition of vegetable fat, purely vegetable alterna- Paland, project manager at WS Warmsener ers respond to these needs. tives without milk or even replacing the sugar with Spezialitäten GmbH. Joe Katterfield, Business Development certain sugar substitutes," says Johannes Rother, The company also intends to supply the Asian Manager for Sports Nutrition and Health Foods at Managing Director of WS Warmsener Spezialitäten region with the new recipes and container sizes in Arla Foods Ingredients, said: “Protein’s benefits for GmbH, describing the rapidly changing require- the future. In countries such as Vietnam or muscle growth, recovery and weight management ments of his customers. The company reacted by Indonesia, for example, sweetened condensed milk have driven consumer demand in a range of developing new varieties and also has certified its is traditionally used for whitening and sweetening categories. But while the high-protein trend is products for various standards to meet these new tea, and there is a correspondingly high demand definitely here to stay, manufacturers also have to requirements. for GKM in the tea rooms that are widespread there. meet many other needs. MicelPure™ combines The dairy in Warmsen is currently a pioneer in At the same time, this market in particular is seeing high protein levels and functionality with an offer the market for organic certified sweetened growing demand for the new recipes with added of healthy wholesomeness that increases appeal.” condensed milk, as well as for Fairtrade-licensed vegetable fats or the purely vegetable alternatives. Samples of MicelPure™ are available for food condensed milk. When using vegetable fats in By expanding its product range with new applications such as cooking-stable cheeses, the new recipes, the procurement of sustainably recipes and investing in new packaging options, the yogurts and ice cream and puddings, as well as produced raw materials is a particularly important company believes it is well equipped to expand its health and performance applications, such as criterion; here the company uses RSPO-certified export activities and at the same time further ready-to-drink high-protein beverages and palm fat, for example. As a central organization, consolidate its leading position as a supplier of powder shakes. RSPO (Roundtable on Sustainable Palm Oil) sweetened condensed milk for B2B customers Reference: 1 Lindberg International‘Consumer study on perception of organic food products promotes sustainable cultivation methods for palm throughout Europe. and organic purchasing habits’, 2019 oil in the producer countries and has defined www.ingredients.uelzena.com www.arlafoods.com

www.innovationsfood.com | August 2020 | Innovations in Food Technology 75 BAKERY:TESTING 13/8/20 15:51 Page 2

Kara Lantmännen Unibake completes expands in Norway £1 million he international bakery company, Lantmännen Unibake, has acquired the investment in production assets from French Bakery Company AS, a Norwegian bakery located close to new doughball Drammen. The acquisition is a key step to provide sustainable products and bakery solutions in Norway and to meet consumer demand for locally production produced bakery products. The acquisition includes the take-over of plant French Bakery Company’s production equipment and employees and it strengthens Lantmännen Unibake’s unique position in Norway. It will provide opportunities for expansion with new products for Unibake. ara, the foodservice arm of Finsbury foodservice and retail. It also enables insourcing to “Lantmännen Unibake Norway sees strong Food Group, has invested over £1m in Lantmännen Unibake’s local bakeries and supports growth potential for bake-off products in Norway new production plant at its Manchester the international bakery group’s focus on core and our focus is to meet the needs of our site. The major investment will directly enhance markets and sustainable production. foodservice and retail customers. With increased production efficiency and help improve the “French Bakery Company is a modern bakery flexibility, tailor-made and locally produced bakery’s capabilities and efficiencies. with high bake-off expertise and quality standards. products, the acquisition will expand our current The plant investment has gone towards the Geographically, the bakery is well positioned for our offer. It enables our business to strengthen our installation of a new doughball plant and freezer current Norwegian operations and fits into our sustainability efforts through locally sourced raw capability. This includes a brand new freezer, strategy and ambition. Building on our focus on materials and locally produced products, while also feeding system, product conveyors, check sustainability from field to fork, locally produced supporting our target to reduce the CO2 footprint weigher, new metal detector and hand-packing bakery products and short time-to-market, we through shorter transportation distances,” station. Structural improvements have also been believe there is a very good potential to grow the says Thomas Bjarkholm, Managing Director of made to the building fabric including a replace- business further and continue to deliver great Lantmännen Unibake Norway. ment of the floor area and installation of energy results,” says Werner Devinck, CEO of Lantmännen www.lantmannen.com efficient LED lighting. This multi-million pound investment will deliver numerous benefits to the site; most signif- icantly, it is anticipated that the new plant will increase capacity by 30%. Alongside the increased manufacturing capability, it is also predicted that less downtime and product wastage will be incurred. NOVEMBER 2020 ISSUE Jon Cooper, Business Unit Director at Finsbury Food Group, commented: “With much of Kara’s customer base closing during the lockdown the Innovations in Food Technology will be widely past few months have been a challenging period both for Kara and the Finsbury Food Group. It did, distributed at Fi & Ni Europe in Frankfurt. however, provide us with the perfect time to completely install and commission the new plant. This new installation protects and significantly increases our manufacturing capacity and Reserve your advertising / editorial space now importantly brings about less manual handling. We have already seen improved product quality and and showcase your company to these two major consistency. “This investment has come at an important trade shows and thousands of visitors. time. Doughballs have been identified as an increasingly important range within our product portfolio. We know that many foodservice operators and wholesalers are looking at menu shrinkage and switching to ingredients that offer Contact multi-use. Our doughballs are sufficiently versatile David Copperfield at to be used across all day parts and in a cross- section of dishes and cuisine types. [email protected] “The new Kara website suggests numerous ways that doughballs can be used alongside the or traditional pizza base including the likes of garlic terry Prior at [email protected] doughballs, cinnamon rolls, flatbreads, interna- tional dishes like Turkish Pide and even a Chocolate S’mores for dessert menus.” https://karafs.co.uk/

76 Innovations in Food Technology | August 2020 | www.innovationsfood.com BAKERY:TESTING 13/8/20 15:51 Page 3

KaTech launches new brand for low dosage bakery concentrate

he food technology and ingredient “In recent years bakery manufacturers have company KaTech Katharina Hahn + seen raw material prices for flour and sugar soaring Partner has launched a new brand and therefore are seeking for new solutions representing a super low dosage bakery concen- enabling them to safe cost. With that trend we see trate concept for the bakery industry. The new a real push in the market to move away from brand is called KaTech Scratch Plus and has been mass baking mixes and towards scratch-based developed to help manufacturers to produce more formulations,” says Stephen O'Neill, Technical Sales cost-effective baked goods across all bakery Executive for Bakery at Katech. applications. KaTech Scratch Plus concentrates can be KaTech Scratch Plus concentrates are designed tailored to individual customer demands like gluten to provide only the key functional ingredients free, vegan and clean label but also classic and sugar needed to produce stable high-performance and fat reduced products to ensure the best bakery products.Thus bakery manufacturers are performance based on customers raw materials given the flexibility to source bulk commodity raw and factory process. materials such as flour and sugar at the best In most cases, each KaTech Scratch Plus possible price, avoiding unnecessary expenses for concentrate can be used to produce a number of such raw materials added to a blend, ultimately different bakery products, whereas, other bulk keeping costs to a minimum. bakery mixes are designed for one product only. Silvery Tweed sprouts new Wheat and barley malt syrup product lines ereal, grain, and seed processor Silvery added to Cargill’s label-friendly Tweed Cereals has added sprouted grains to its product range to help bakeries and cereal manufacturers meet consumer demand for sweetener options for European natural, healthy, and nutritious products. The Berwick-Upon-Tweed business now offers wheat, spelt, rye and buckwheat sprouted grains in food manufacturers flaked, kibbled, cracked and flour formats. Unlike the wet formats currently on the onsumers increasingly demand more SweetPure is only 25-40% as sweet as sugar, market, the grains used by the Silvery Tweed team from the foods they consume, embrac- depending on the concentration. have been carefully dried after sprouting, which ing products made with familiar and “Given its mid-range sweetness, SweetPure can allows them to process the grains in the same way minimally processed ingredients. To help food be used to formulate baked goods and cereal as a non-sprouted grain. manufacturers deliver on these expectations, Cargill products with more balanced sweetness or as a first NPD Manager Julie Telfer says, “The healthy has launched SweetPure™ M Wheat and Barley Malt step towards reduced-sugar formulation to meet eating trend continues apace, and demand for Syrup, a label-friendly, unrefined sweetener devel- the needs of health-focused consumers,” added new and innovative products that tick the natural, oped for bakery, snack bar and cereal applications. Chouvy. nutritious and healthy boxes remains high. “We live in the age of mindful consumers, who “SweetPure represents an important addition “Sprouted grains contain all of the original want to know all about the food they buy, to our already extensive nature-derived sweetener bran, germ, and endosperm and, as such, are including how the ingredients are considered whole grains. This means that they are grown and processed,” said naturally high in fibre, and evidence suggests that Phillippe Chouvy, Cargill’s business their use in food products also results in an increase development manager for sweet- in soluble fibre. eners in Europe. “Food manufac- “In addition, the sprouting process breaks turers need simple ingredients down nutrients such as starches and proteins, that address the needs of these making the grains easier to digest. Finally, a label-conscious consumers.” reduction in the amount of the antinutrient SweetPure, which labels phytate present in sprouted grains increases the simply as wheat and barley malt bioavailability of nutrients to the body. syrup, fits those demands to a “Incorporating sprouted grains opens up tee. Cargill’s proprietary research opportunities to create new and innovative suggests consumers view wheat products that will meet consumer demand in a and barley malt as familiar competitive market.” ingredients, ranking them posi- Julie says that the sprouted flakes make a tively. Adding to its appeal, the great addition to cereals such as mueslis and unrefined syrup meets ISO natural granolas. The kibbled grain and flour formats work definition. portfolio, which includes full-, mid- and no-calorie well in breads, crispbreads and biscuits. As the syrup is unrefined, it has a light grainy solutions,” said Ann Dierickx, Cargill’s sweetener Silvery Tweed manufactures cereal products, taste and pale-yellow color that pairs well with most product line manager in Europe. “Combined including flour, cereal flakes, grain, and seed bakery, snack bar and cereal flavor profiles. While it with our application, formulation and technical blends, and supplies bespoke products to many of functions similarly to high maltose syrups in expertise in bakery and cereals, we’re now even the UK’s leading cereal and bakery brands. formulations, its straightforward ingredient better positioned to support our customers’ needs, For more information about the new sprouted description and minimally processed nature appeals whether it’s for reformulation or new product grains range and potential applications, contact to consumers. development projects.” Silvery Tweed. Beyond its label-friendly credentials, www.cargill.com www.silverytweedcereals.co.uk

www.innovationsfood.com | August 2020 | Innovations in Food Technology 77 NEW PRODUCTS:TESTING 12/8/20 16:42 Page 2

Plant-based colours can give plant-based products the edge – EXBERRY® Coloring Foods supplier GNT

lean-label colours are key to differentia- recent decades. out any chemical solvents, ensuring they are 100% tion in the increasingly competitive plant- With many consumers now reducing or vegan-friendly and support clean and clear based market, according to GNT Group. eliminating animal products from their diet1,2, labelling. The EXBERRY® Coloring Foods supplier has plant-based alternatives are experiencing Maike Frerichs, who leads GNT’s plant-based launched new resources on its website to highlight phenomenal growth in demand. category team, said: “We are heading toward the importance of colour in vegan-friendly meat, As of last year, annual global sales of plant- ‘plant-based 2.0’, with manufacturers reformulat- dairy, cheese and fish alternatives. based meat substitutes had grown by an average ing their products to meet modern consumer GNT has also produced an animated video of 8 percent annually since 2010. The plant-based expectations. As such, using plant-based colours charting the rise of plant-based food and drink – as beverage market, meanwhile, grew approximately for plant-based products has never been more well as the evolution of colours – through 33% each year between 2014 and 20193. important. EXBERRY® Coloring Foods offer a With more options on the shelf than ever future-proof solution, helping to deliver an ideal before, it is vital that plant-based food and drink appearance while maintaining clean and clear products deliver a fresh and appealing appearance. labels.” In this health- and ethics-driven category, To learn more about the importance of colour consumers are motivated to demand clean-label, in plant-based meat, dairy, cheese and seafood plant-based ingredients4. products and watch the animation, visit: EXBERRY® offers the widest range of Coloring https://exberry.com/plant-based Foods on the market, helping to ensure that plant- References: based meat, dairy, cheese and seafood alternatives 1 YouGov 'Young Americans less likely to be meat-eaters' (January 2020) deliver the visual impact desired. 2 YouGov 'Is flexitarianism the diet of the future?' (March 2019) ® 3 National Research Council Canada 'Plant-based protein market: Global and In addition, EXBERRY Coloring Foods are made Canadian market analysis' (March 2019) from fruit, vegetables and edible plants and with- 4 Euromonitor International 'The Unstoppable Rise of Plant-Based Alternatives' (March 2020) Whole-cranberry urinary health formula Flowens®

lowens®, Naturex’s patented natural nied by frequency and nocturia (waking up during formula for urinary health, has been the night to urinate). Prevalence of OAB ranges named Ingredient of the Year – Healthy from 9%-43% in women. Ageing at the 2020 NutraIngredients Awards. Flowens® taps into growing consumer demand Produced from a full-spectrum cranberry for non-pharmaceutical, natural solutions that blend, Flowens® has been clinically shown to address urinary symptoms. improve lower urinary tract symptoms (LUTS) in men Dan Souza, Global Product Manager, said: health claims related to prostate and lower urinary at daily doses of 250mg and 500mg. The most “We’re delighted Flowens® has been chosen as tract health - six from Health Canada and one from common LUTS include difficulties associated Ingredient of Year – Healthy Ageing. The likelihood the Colombia National Food and Drug Surveillance with voiding the bladder and storage of urine. of being affected by urinary symptoms greatly Institute (INVIMA). Prevalence increases with age: it is found among increases as we get older. In fact, for many, suffer- It is produced from sustainably grown cranber- 26% of men in their 40s, and 90% in their 80s. ing from bladder symptoms is not a matter of ‘if’ ries sourced from a supply chain that has achieved Following a recent clinical study, the use of but ‘when’. Flowens® is a natural, clean-label Gold Status in the Naturex industry-leading Flowens® has been extended to women, with solution for urinary symptoms that could improve Pathfinder program. It is also sold with a Naturex ID results showing improvement in overactive bladder the quality of life for millions of people worldwide.” Pack to validate its botanical identity. (OAB) symptom at a daily dose of 500mg. OAB is Flowens® is proven to be safe with no side- the presence of urinary urgency, usually accompa- effects and is further supported by seven approved www.naturex.com

78 Innovations in Food Technology | August 2020 | www.innovationsfood.com NEW PRODUCTS:TESTING 12/8/20 16:42 Page 3

A natural and multifunctional W8 Solution gum well known in oenology incorporates Biomega® cacia gum is secreted naturally on certain varieties of acacias, and collected following an incision on the trunk of wild peptides in trees located in the south of the Sahel in Africa. Beyond the naturalness specific to the product, the new weight harvest is also 100% natural. Its many advantages such as its resistance to management acidity and heat, its low caloric intake and its high fiber content are already well known in the food industry and make it an additive of choice used in supplement many everyday consumer products. In the wine iomega Group (‘Biomega’), a leading industry, acacia gum has also been known and used biosciences company producing high- for many years. quality ingredients for the health and "Acacia gum is unique and has the distinction of nutrition industry, has announced a new partner- being extremely effective at almost infinitesimal SupAgro, whose objective is to elucidate the ship with W8 Solution to include its salmon doses of use (0.5 g / liter of wine on average)" physicochemical mechanisms behind the effec- peptides as an ingredient in an innovative weight underlines Virginie MOINE, Scientific Director at tiveness of acacia gum and to highlight its proper- loss product. Biolaffort. She adds: "Gum has been used empiri- ties in this very special application1”. With worldwide obesity increasing year-on- cally since the 1930s, but we did not know precisely year, there is a growing trend towards using weight Reference: the mechanisms of action on a colloidal scale that 1 The colloidal stabilization of young red wine by Acacia senegal gum, Michael Nigen, management products. According to the stabilize the coloring matter of wines. Hence the Rafael Apolinar Valiente, Nerea Iturmendi, Pascale Williams, Thierry Doco, Virginie Norwegian Institute of Public Health, one in four Moine,Arnaud Massot, Isabelle Jaouen, Christian Sanchez - Food Hydrocolloids 97 ambitious tripartite research contract which unites (2019) middle-aged men and one in five middle-aged Biolaffort and Alland & Robert at the University of women are obese. The use of Biomega peptides Montpellier www.allandetrobert.com in W8 Solution products aims to combat this challenge and promote a healthy, active lifestyle. Marianne Warnaer, Director of Global Sales, at Biomega said: “We are delighted to work with W8 Solution and include our salmon peptides in its ISO classifies Taiyo’s Sunfiber® unique patent pending slimming product. Processed from fresh Norwegian salmon by our natural enzymatic hydrolysis, Biomega® peptides as a natural ingredient contain more than 90% hydrolysed proteins and over 20% collagen peptides (type I and III), which ccording to the International Organiza- are proven to have a positive effect on skin health. tion for Standardization technical In addition, our bioactive salmon peptides have specification, ISO 19657:2017, Taiyo’s anti-inflammatory properties, help maintain stable Sunfiber© dietary fiber is a 100% natural ingredient. blood glucose levels and support weight manage- This is good news for food manufacturers. Not only ment, making the ingredient beneficial for W8 can they simplify the certification process for their Solution users.” own products, they can also use the “natural dietary Developed by Provectus Pharma, which fiber” claim on their product labels. creates advanced dietary supplements, W8 At the same time, consumers who are Solution has a unique blend of EU approved increasingly concerned about the origin of their ingredients that aid long-term and safe weight food and value naturalness, also benefit from the reduction. The innovative combination of gluco- guaranteed quality of the ingredient. To recognize mannan, raspberry ketones, Vitamin C and salmon whether or not a product contains a natural and/or © shutterstock Vinod K Pillai peptides are beneficial in helping the body to a synthetically produced dietary fiber is not easy. stabilized blood glucose levels. For this reason, stabilise blood sugar levels, contributing to normal There are a lot of chemically modified, polymerised, Sunfiber© has achieved a Health Claim for lowering metabolism of fatty acids and energy. With no denatured or synthetic fibers on the market that, at after-meal blood glucose levels by 20% from the known side effects, the formulation enables users first glance, look familiar and appear to be natural, Canadian health authorities. It comprises 100% to suppress hunger, making it easier to support as denatured starch or polydextrose. partially hydrolysed guar gum from the Indian Guar their weight loss goals. “In today’s climate of adulteration and Bean (Cyamopsis tetragonolobus) and is Taiyo’s “W8 Solution is designed with simplicity in contamination, it has never been more important versatile all-round water-soluble solution when it mind.” Marcus Slinning, COO at Provectus Pharma to take every necessary step to ensure ingredient comes to enriching food and beverages with AS, commented. “It’s been developed to help users quality,” says Dr Stefan Siebrecht, Managing digestive fibers. Sunfiber® acts as a probiotic in the lose weight without making major changes to their Director of Taiyo Germany. “Pure and safe raw gastrointestinal tract and helps to slow down and lifestyle. The active ingredients in W8 Solution materials are the measure of all things for us and a reduce the absorption of fat, cholesterol and sugar. suppress hunger, enabling users to eat smaller prerequisite for high-quality products. We would, It is compatible with a low FODMAP diet because its portions, while continuing to consume a healthy for example, welcome an officially authorized fermentation rate is very slow, which means that it diet. The addition of chromium, magnesium and organization that certifies natural products.” doesn’t induce painful gas, cramping or discom- Vitamin C also aid in stabilising blood sugar levels “As a result,” he continues, “companies could fort. and improve blood vessel function, leading to a communicate this certification to consumers. Close Taiyo, which specializes in plant-based concepts stronger immune system.” supplier relationships and quality control based on with nutritional benefits, is constantly working on Designed to be taken three times a day, the strictest regulations and standards are there- new concepts and is going to certify more about 30 minutes before breakfast, lunch and fore part of our daily business. Our customers can products to differentiate them from synthetic ones. dinner, W8 Solution is dissolved into a glass of rest assured that they’re buying genuine, natural water. Reference: raw materials of the highest quality from us, which 1 Confirmed by the Bureau of Nutritional Sciences, Food Directorate, Health Canada, For more information on W8 Solution, please subsequently contribute to clean labelling.” Ottawa, on 25 April 2013 visit https://w8solution.no/. Or for further infor- Backed by science, Sunfiber® is clinically proven mation on Biomega salmon peptides, please visit to lower the glycemic index, contributing to www.taiyogmbh.com https://biomegagroup.com/.

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Nestlé launches YES! Plant Protein bars powered by nuts and peas estlé has launched a new range of its YES! Unlike most other protein bars, the new YES! snack bars, with each bar containing 10 protein bar is tapping into an emerging trend grams of plant protein from a delicious towards pea protein. This opens a new choice to natural combination of nuts and peas. those consumers looking for more innovative plant Recent Nestlé research has shown that most protein alternatives. And the new bars achieve this Cargill offers people buying protein bars are now looking for without any compromise between 'healthy' and more natural protein sources with no additives. 'tasty'. new addition to Plant protein is one of the most preferred options The new bar comes in two delicious flavours: to fuel an active lifestyle and get the most out of Almond, Peanut and Double Dark Chocolate; and their busy day. Cashew, Blueberry and Dark Chocolate. Nuts are the sweetener The new YES! Bar packs in 10 grams of plant number one ingredient, and the bars are drizzled protein from peas and nuts and gives consumers with real dark chocolate made with sustainable power on the go. Like other YES! bars, the new cocoa certified by the Rainforest Alliance. portfolio to food protein bars are made of wholesome ingredients, The bars will be available from September 2020 are high in fiber, use no artificial colors or preserv- in European countries including the UK, Germany, and beverage atives, are gluten free and suitable for vegetarians. Netherlands, and the Czech Republic. manufacturers

ood and beverage manufacturers in Europe who are looking for label friendly, reduced sugar options can look to Cargill’s newest sweetener C$TruSweet® 01795 to enable a 30% sugar and calorie reduction in beverages and other food applications via lower usage levels. “Soft drinks and sugar-laden foods have come under regulatory scrutiny, and with the establish- ment of various national sugar taxes, manufactur- ers are looking for simple, innovative solutions, without impacting the sweet taste consumers DSM boosts maternal and infant expect,” said Phillippe Chouvy, Cargill’s Business Development Manager for sweeteners in Europe. Cargill’s C$TruSweet® 01795 is a 95% pure nutrition portfolio withnew fructose syrup that is characterized by a naturally higher relative sweetness than sucrose. It delivers plant-based high potency DHA oil the same sweet taste at lower usage levels there- fore enabling the 30% sugar and calorie reduction oyal DSM, a purpose-led, global science- turers develop high-quality, reliable DHA solutions that and an even further reduction when combined based company active in Nutrition, will give pregnant women and moms peace of mind with high-intensity sweeteners. As fructose is a Health and Sustainable Living, has and that will shape healthier futures worldwide.” natural occurring sugar, and often referred to as announces the launch of its new, high-quality fruit sugar, it answers consumer demand for life’sDHA® SF55-O200DS oil for maternal and early Science supporting the use of DHA in nature-derived, recognizable ingredients – its fast life nutrition solutions. Offering a higher potency, maternal and infant nutrition sweetness onset enhances freshness and it boosts this ingredient contains a minimum of 550 mg/g Evidence indicates that optimal omega-3 DHA fruity flavour notes, making it a perfect match for natural triglyceride DHA (docosahexaenoic acid), intake plays an essential role in life-long health and fruity beverages and food, such as fruit prepara- allowing manufacturers to achieve equivalent development, particularly in infancy during the first tion and fillings, ice creams, dairy and sports dosages of DHA in smaller product formats and 1,000 days – between the onset of a woman’s nutrition products. meet the latest maternal nutrition trend for pregnancy and her child’s second birthday. A Cochrane ‘With Cargill’s already extensive nature-derived convenient capsule and tablet sizes1. review of omega-3 long-chain polyunsaturated fatty sweetener portfolio, from full- to no-calorie This latest addition to DSM’s broad nutritional port- acids (LC-PUFAs) recommendations shows that DHA and solutions, adding more simple solutions that folio is the only 550 mg/g natural triglyceride DHA EPA (eicosapentaenoic acid) lowered the risk of having enable sugar reduction to our portfolio enhances intended for use in maternal nutrition and is aimed for a preterm baby by 11%, and an early preterm baby by the offerings we can make to our customers in women who are planning to conceive, are pregnant, 42%2. The most effective doses were shown to be Europe. Combined with our application, formula- breastfeeding or non-breastfeeding post-natal between 500 mg and 1,000 mg of DHA and EPA per tion & technical expertise in beverages and food, mothers. Produced from Schizochytrium algae, day, where at least 500 mg is DHA3. we can now better support our customers’ needs, life’sDHA SF55-O200DS offers a sustainable plant-based The life’sDHA brand represents DSM’s commitment whether it’s reformulation or new product devel- alternative to fish oil and is made with ingredients of to safety, quality and reliability, offering mothers and opment projects,” continues Chouvy. conventional (non-GM) origin. A trusted source of pregnant women the reassurance that they and their As stevia-based sweeteners have quickly contaminant-free, kosher and halal omega-3, life’sDHA children are consuming safe products that are free of become a favourite high-intensity sweetener, SF55-O200DS supports infant health and development ocean-borne contaminants, like mercury, associated Cargill’s C$TruSweet® 01795 can also deliver and can be consumed in a single, convenient dose. with fish and fish oils. greater sugar and calorie reduction targets of 65% “Convenience, quality and safety are key drivers of For more information on DSM’s purpose-led when combined with stevia. The combination consumer purchasing in the maternal and early life nutritional lipids portfolio and expert services for works well as fructose is fast in sweetness onset nutrition markets, with mothers and expectant moms maternal and early life nutrition that support and stevia creates more lasting sweetness. looking for easy-to-swallow dietary supplements and producers from concept development to production Furthermore, in comparison to crystalline fructose, safe infant nutrition products made with trusted, and beyond, visit our website www.dsm.com. C TruSweet® 01795 is a ready to use syrup that science-backed ingredients, comments Brent $ References: offers manufacturers significant cost benefits for MacDonald, Director Global Marketing & Business 1 DSM, maternal nutrition, consumer attitude and usage study, 2019. their sugar reduced formulations. Development, Nutritional Lipids at DSM. “We carefully 2 Middleton et al., 2018. 3 Ibid. www.cargill.com formulated life’sDHA SF55-O200DS to help manufac-

80 Innovations in Food Technology | August 2020 | www.innovationsfood.com NEW PRODUCTS:TESTING 12/8/20 16:43 Page 5

Novel flavours with a story to tell

ensient Flavors presents its new collection component for foods. of ‘Trends to Taste’ flavours. With their Young consumers, in particu- sophisticated flavour profile, the new lar, focus on holistic wellness and creations are more than just ingredients to excite often look upon food as a form of © JurateBuiviene Shutterstock and delight consumer palates. Based on the epony- medicine. Multi-functionality and health benefits are has notes of cedar, vanilla and licorice, bringing a mous company report on the latest global socio- therefore an intrinsic part of their expectations. spicy touch to savoury foods, baked goods, desserts cultural shifts and trends, they provide inspiration Ajwan, a traditional Indian spice, fulfils both needs – and even beverages. for up-to-date product launches and targeted as a culinary ingredient and Ajurvedic remedy. The James Street, Marketing Director EMEA, brand positioning. What’s more, the flavours can sweet, pungent and bitter Ajwan flavour from comments: “The intention of “Trends to Taste” is not serve as a basis for the spinning of captivating tales Sensient Flavors combines notes of thyme, only to inspire innovation, but also provide action- around the end product too. oregano, cumin and anise, and helps food manu- able insights to narrow the gap between a brand Multifaceted flavour Strega was inspired by facturers bring added value to their products. and its consumers. At Sensient, we believe that niche products that have become an integral part “Smart homes” and cyborg technologies are understanding consumers in the broader context of mainstream culture. Named after an Italian just a couple of examples of the interconnected- of socio-cultural trends is vital in order to drive herbal liquer, the flavour offers a complex mix of ness that shapes our world today. The outcome of stronger product performance in the marketplace. cinnamon, juniper, mint, anise and fennel. The this connection is more than just the sum of its We encourage our clients to use the insights of our liquer, originally used for its medicinal properties, is parts. Much like “Ispahan” - the signature dessert of latest trend report to innovate and create value for now enjoying a renaissance as a digestif and cock- the legendary pastry chef Pierre Hermé, made of their consumers.” tail constituent. The Strega flavour has numerous rose, raspberries and lychee. When merged Published annually, the ‘Trends to Taste’ report application possibilities and delivers a unique taste together, these individual ingredients create a gives a comprehensive picture of the current kick to a variety of foods and drinks. wonderfully surprising taste combination; at the factors affecting consumers’ mind-set and Today, flavours synonymous with certain foods same time, the sweet and creamy Ispahan flavour behaviour. It is based on the company’s own trend and drinks are seeping into the wider public captivates with the harmony of fruity and floral monitoring program consisting of i.a. data analysis consciousness as part of an evolving social trans- notes. from syndicated research, in-depth market formation. Sensient Flavors exemplifies the idea of Sensient Flavors’ aromatic mix Tears of Chios excursions, tracking social media, and speaking to qualitative change with Oud flavour. The musky, pays homage to Mother Earth and her unique gifts end consumers locally. “Trends to Taste” flavours warm woody and balsamic notes come from the – treasured more than ever at a time of environ- symbolize the latest influences of today’s world and tropical agar tree. When the tree gets infected with mental instability. In a process unchanged for the contribute to captivating storytelling through the a parasitic mold, its wood starts producing fragrant past 2500 years, residents of the island Chios in the final product. resin. As the result, the original disease helps create Aegean Sea harvest the resin of the mastic tree. The one of the most expensive ingredients for the hardened liquid, washed by hand and dried is perfume industry, as well as a promising flavour known as “Tears of Chios”. The eponymous flavour www.sensient.com

Hydrosol: Exclusive texturates with structure similar to muscle tissue

lant-based alternatives to meat and HACK® product. We have built a special reputation sausage remain in high demand by and capabilities in the area of sunflower protein- consumers, and this interest and the based vegan products, like burger ready mixes. Our trend to this product category have scarcely been plant-based proteins, especially Heliaflor®, are affected by the current corona crisis. On the derived through the partial de-oiling of high-quality contrary, awareness of the importance of sustain- raw materials. During production we take special sunflower protein wet texturates, and our knowl- able and balanced nutrition is rising, worldwide. care to protect their beneficial properties. As a edge of stabilisation and texturing of plant-based Industry experts expect to see continuous growth in result, our products retain their native protein meat alternatives, we can develop a broad plant-based alternative products in the coming structure and content of important nutrients like B spectrum of individual product solutions that give years. “Whether for ethical or environmental vitamins, secondary plant substances and minerals. our customers unique selling propositions on the reasons, reduced meat consumption is the future of This distinguishes them from conventional protein market.” Another plus point is that the texturates the food industry. This is even more important products. The functional properties, especially those are available in conventional as well as organic in view of the need to supply a growing world of our sunflower protein, are further significantly versions. population with sustainably sourced, protein-rich affected only by the production process.” There remains the challenge of getting the meat alternatives,” explains Dr. Matthias Moser, The proteins are a by-product of sunflower oil colour and flavour of the sunflower texturates just Managing Director Hydrosol. manufacture, so there are clear advantages in terms right, for example to avoid unpleasant aftertastes. This specialist for stabilising and texturing of sustainability. Hydrosol uses three different “Sunflower texturates are naturally dark. For systems is now working in close collaboration with texturates for the production of meat and sausage sausages, burgers and other ground meat alterna- raw materials supplier All Organic Treasures (AOT). alternatives – a dry texturate for plant-based mince tives that’s not a problem, in fact it’s a benefit. But The goal of the cooperation is to combine the like burger patties, a dry texturate with fibrous for nuggets or filet strips that are supposed to be expertise of both companies and offer customers in texture for foods like nuggets, and a wet texturate like chicken, a light colour is naturally preferable. We the plant-based meat alternative space a wider with a structure similar to muscle tissue for plant- can adjust for this very well through combination range of products with individualised and exclusive based filet strips. “Plant-based muscle tissue alter- with other protein concentrates. In our Plant Based solutions. The focus is on allergen- and GMO-free natives remain a big challenge for the industry,” Competence Center we have already been getting protein sources with a positive image, like sunflower. notes Hydrosol Product Manager Florian Bark. “Their very good results in a range of application tests,” According to Fabian Breisinger, Managing Director authentic meatlike structure gives wet texturates reports Florian Bark. AOT, “Our own Sunflower Family brand is already from plant protein great potential. With the successful in food retail with the Sonnenblumen- expertise of AOT as manufacturer of these www.hydrosol.de

Innovations in Food Technology | August 2020 | www.innovationsfood.com 81 NEW PRODUCTS:TESTING 12/8/20 16:43 Page 6

INFUSE by Cargill™ addresses Fishalternatives rapidly evolving consumer – The new demands withcustomized heroes of the ingredient blends in Europe plant-based

NFUSE by Cargill™ for European customers revolution brings together the company’s extensive ingredient acumen to rapidly create tailor- he “plant-based revolution” is the term made ingredient blends. Our expertise gives food Innova Market Insights uses for the and beverage manufacturers an edge in making continuing worldwide boom in plant- products that address a complex set of consumer based food and beverages. In the US and in demands, such as sugar and calorie reduction, Europe, for example, the demand for meat label-friendly, plant-based and other “free-from” alternatives is rising rapidly. According to experts, formulation challenges. INFUSE by Cargill mirrors one reason is that the Corona crisis has made many the Functional Systems’ portfolio of ingredients and more consumers rethink their eating habits. In blending technologies available to customers in addition to health and enjoyment, safety, environ- North America and Asia Pacific regions. ment and animal welfare are becoming more and “Consumers desire healthier products made team, they can leverage Cargill’s resources, more important to consumers when buying foods. with less sugar and fewer calories, while still including kitchen and prototyping facilities, along Plant-based alternatives to meat, sausage and expecting a great taste, mouthfeel and memorable with the company’s legal, regulatory, marketing, dairy products have long since gone mainstream, eating and drinking experience,” says Denise Mc formulation and technical expertise in bakery, and fish alternatives are now the next big thing in Carthy, who leads the product line. “Those are high confectionery, dairy and beverage applications. vegan products. For Florian Bark, Hydrosol Product expectations and require a different approach to For Hannah Keenan, Business Development Manager, they are the “plant-based stars for 2020.” ingredient formulation. INFUSE by Cargill, which Manager for INFUSE by Cargill, it all boils down to “The primary reasons for choosing plant-based sits at the crux of reformulation and innovation, speed. “We understand how ingredients work substitute products are aspects like sustainability, represents the way Cargill helps our customers together and how to create optimal solutions,” she animal welfare and climate change. This is where succeed.” says. “With more than 300 ingredients in our the fish alternatives come in. Environmental Customers in Europe have been using Cargill’s toolbox, we can quickly develop, deliver and functional systems for more than 40 years to optimize prototypes, dramatically shortening bench achieve custom texturizing ingredient blends. development time.” INFUSE by Cargill expands on that work, adding Three pillars serve as the foundation for Cargill’s sweetness and other specialty ingredients such as customer focus in Europe: an unwavering attention proteins and fibers, to address a broader array of to providing on-trend solutions, a commitment to customer formulation challenges. speed to market, and access to deep technical “No two blends are ever the same,” Mc Carthy expertise to create ingredient blends tailored to emphasizes. “We always start by understanding meet each customer’s unique needs. each customer’s requirements, then use our “Given today’s complex formulation challenges, technical expertise to land on the right combina- the days of solving problems with a single tion and ratio of ingredients.” ingredient are gone,” Mc Carthy says. “However, Small- and medium-sized food producers in with INFUSE by Cargill, we can offer customers the Europe reap the biggest rewards from INFUSE by ease of a single solution – to help speed up their Cargill. These companies often have more limited development and launch innovative products faster R&D, regulatory, legal and technical support to market.” resources. By partnering with the INFUSE by Cargill www.cargill.com

Nektium introduces immune organisations advise cutting back on consumption of ocean fish, due to overfishing. Aspects like microplastic are further arguments.” Hydrosol has booster Echinacea angustifolia already developed various product ideas for this new segment. For example, with the HydroTOP ektium has expanded its portfolio of is an ingredient 100% made in the EU.” VEGAN RB 5 full compound, plant-based alterna- standardized botanical ingredients with Whilst there are many products containing tives to breaded fish sticks and fish filet can be Echinacea angustifolia. It’s an ingredient different Echinacea species, the ingredient provided made based on a rice texturate. Another new with historical use and scientific evidence for by Nektium is a standalone product from Echinacea product is alternative tuna, which looks and tastes supporting the immune system and strengthening angustifolia – a herbal remedy that was traditionally like canned tuna and can be used in many differ- the body’s resistance to bacterial and viral used by Native Americans, primarily to treat upper ent ways. diseases. respiratory tract infections and snake bites. Since 2014 the Hydrosol line of plant-based The ingredient is produced from Echinacea Scientific research furthermore emphasizes the concepts for meat and sausage, dairy products, angustifolia roots and standardized to 4 percent immune-stimulating properties of Echinacea deli foods and convenience has expanded rapidly. echinacoside, the major polyphenol prevalent in the angustifolia as well as the applicability as anti- Fish alternatives are among the latest new root. “We have established a transparent inflammatory. products from the Plant-Based Competence supply chain with an accredited European raw Besides other ingredients such as Elderberry Center. “Plant-based alternatives to fish products material supplier, backed by our established ID that are already established in the product are just a step away from going mainstream,” says testing to ensure the quality of our ingredient”, says portfolio, Echinacea angustifolia is the most recent Florian Bark. “Many manufacturers are looking to Deborah Thoma, Marketing Manager at Nektium. addition of immunostimulant ingredients. us for new concepts in this category, which has “Since we manufacture the ingredient in our GMP- enormous sales potential.” certified production plant on the Canary Islands, this www.nektium.com www.hydrosol.de

82 Innovations in Food Technology | August 2020 | www.innovationsfood.com NEW PRODUCTS:TESTING 12/8/20 16:43 Page 7

DSM debuts integrated portfolio of solutions for winning plant-based meat alternatives

oyal DSM has unveiled its complete port- that also offer an appealing nutritional profile, DSM’s folio of integrated solutions for creating Quali® vitamins and DSM Premix Solutions can be stand-out plant-based meat alternatives. added to fill the gaps in the nutritional profile of The range is designed to enhance taste, texture and plant based products, while the Maxavor® RYE LS nutritional value, while also managing sodium range can deliver a meaty flavour with reduced content in meat alternative applications such as sodium to manage salt content. burgers, sausages and nuggets. Featuring a DSM’s combined ingredient capabilities in taste, selection of yeast extracts, process flavours, texture and nutrition not only enable meat alterna- hydrocolloids and nutritional ingredients, DSM’s full tive producers to optimize the cost-performance portfolio provides food producers with the tools ratio of their recipes, but also am-plify front-of-pack they need to get to this thriving market fast, and claims thanks to DSM’s deep-rooted expertise into meet growing consumer demand for an authentic, nutrition science. enjoyable and nourishing meat alternative experi- presents a range of complex challenges for manu- Gilbert Verschelling, Director Business Develop- ence. facturers in this space. ment & Innovation at DSM, comments “Delivering While the demand for meat continues to grow, DSM’s plant-based meat alternative solutions plant-based products that meet today’s evolving the retail value of meat alternatives is expected to include: high nucleotide yeast extracts, such as consumer demands is no easy task for food manu- more than double this decade. However, as the Maxarome® Select, which help to mask the ‘beany’ facturers. At DSM, we are uniquely positioned to trend gains traction, consumer expectations and off-flavors typically associated with plant-based help producers create truly enjoyable meat- preferences are becoming more sophisticated. It is proteins and create a rich umami taste; Multirome® alternative products that will tick all boxes for no longer enough that a product is plant-based. , which increases juiciness and creates a succulent, consumers. Our complete integrated portfolio of Consumers are increasingly looking for an end-to- fatty mouthfeel and experience; the concentrated solutions for plant-based meat alternatives end experience that offers great taste, compelling Maxavor® flavour range to provide the desired complements DSM’s wider plant-based offering, texture and mouthfeel, as well as a rich nutritional meaty taste direction; and GELLANEER™ gellan gum, including its range of recently launched solutions pro-file. Meanwhile, they expect reduced levels of which enhances water binding capacity for for dairy alternatives.” sodium in their foods – which is typically present in improved juiciness, while also building an authentic high quantities in meat alternative products. This meaty texture and bite. For great-tasting products www.dsm.com

BENEO expands portfolio with new organic ingredients

ENEO has announced the expansion of contains no amylose and therefore delivers better its chicory root fibre and rice starch stability and less syneresis, making it easier to ingredient portfolio with two new organic maintain a stable texture throughout a product’s solutions. The launch of the new additions, com- shelf life. Remyline O AX DR is suitable for fruit prising an organic waxy rice starch, Remyline O AX preparations, as well as meat and poultry DR, and organic chicory root fibre, Orafti®Organic, applications. Technical trials by experts at the paves the way for BENEO to strengthen its market BENEO-Technology Center have shown positive leading position. results for these applications, as well as for improv- Consumers worldwide are increasingly seeking ing the texture of creamy desserts and yoghurts. out organic products, with figures showing they Commenting on the launch of Remyline O AX have become more important to 1 in 4 consumers DR, Marc-Etienne Denis, Commercial Managing in the last year1 and many willing to pay a premium Director Specialty Rice Ingredients at BENEO stated: price for them2. This rising demand has been driven “The launch of BENEO’s new organic waxy rice by the growing consumer perception of organic starch is an important milestone for us as it means products as healthy and natural, and therefore an we can now offer our customers organic variants intrinsic part of a healthier lifestyle. Organic prod- for both our waxy and regular rice starches. We see bakery and confectionery. ucts and ingredients are also considered a vital great potential for this new solution, especially Regarding the launch of Orafti®Organic, Eric element for ethical and sustainable purchasing within meat and poultry, as consumers worldwide Neven, Commercial Managing Director Functional behaviour, a key trend being seen within the food place special emphasis on organic products when Fibres at BENEO, commented: “Requests for organic and beverage industry. Around the world, there are buying meat.” chicory root fibre are constantly growing so we high expectations for organic products, with a BENEO’s new Orafti®Organic, is a carefully are pleased to be able to offer this solution to our compound annual growth rate of 2% and 2.6% in grown and selected organic variant of its popular customers, and be the first in the market to do so. value predicted between 2019 and 2022 in Europe chicory root fibre and yet another first to market. It BENEO is confident this move to expand our and the USA respectively3, the two largest organic is regionally grown and harvested by certified overall organic ingredients portfolio will be highly markets. organic farmers in Belgium. Inulin and oligofructose appreciated by the industry and shows particular The addition of BENEO’s new organic waxy rice remain the only proven plant-based prebiotics avail- promise for new product developments in this starch, Remyline O AX DR, completes the existing able, according to ISAPP (International Scientific growing area of the market.” portfolio of rice starches with the availability of Association for Pro- and Prebiotics). Available to cus- organic solutions for both regular and waxy rice tomers from September onwards, Orafti®Organic References: 1 HFI 2019 starch. Launching globally from July onwards, enables manufacturers to add natural prebiotic 2 HFI 2019 Remyline O AX DR is the first of its kind to be fibres that will improve taste and texture, while also 3 Global Data 2019 brought to market, opening up new possibilities for allowing for fat and sugar reduction in products product development. As a waxy rice starch, it across key applications such as dairy, cereals, www.beneo.com

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CLINICAL STUDY RESULTS - 7 PAGE SECTION

Stronger for longer: New whey ingredient slows age-related muscle decline

ARLA FOODS INGREDIENTS has launched a new CAGR of 80% in Asia between 2015 and 2019.5 and Kosher. On-pack benefits in China include high- whey protein ingredient which is clinically proven to Laima Liepinyte, Business Development in-protein, low-in-lactose, sugar-free and easy-to- counteract age-related muscle mass decline. Manager, Asia at Arla Foods Ingredients, said: dissolve. With a pleasant taste, it is ideal for powder Lacprodan® HYDRO.Rebuild is a 100% hydrol- “Thanks to advances in medical technology, people applications. ysed whey protein. It offers highly accessible are living longer than ever before. However, age Arla Foods Ingredients has been expanding its content of branched-chain amino acids and brings many changes to health, one of which is a presence in the APAC region. As part of its commit- essential amino acids such as leucine, which are natural decline in skeletal muscle mass and ment to Chinese markets, it has launched a new important for muscle synthesis in seniors. function. This can have a devastating effect on version of its website in Mandarin. In three separate clinical trials on resistance- mobility and quality of life but whey protein, in References: trained older women, Lacprodan® HYDRO.Rebuild combination with exercise, can help slow the 1 Junior PS, Ribeiro AS, Nabuco HCG, et al. Effects of Whey Protein Supplementation Associated With Resistance Training on Muscular Strength, Hypertrophy and has been shown to offer significant improvements decline.” Muscle Quality in Pre-Conditioned Older Women. Int J Sport Nutr Exerc Metab. to muscle mass, strength and mobility. Other She added: “The number of health-conscious 2017;(January):1-27. doi:10.1123/ijsnem.2017-0253. 2 Nabuco HCG, Tomeleri CM, Sugihara Junior P, et al. Effects of whey protein documented benefits include a slimmer waist and seniors is skyrocketing, particularly in Asia, and they supplementation pre- or post-resistance training on muscle mass, muscular reduced body fat.1,2,3 are looking for nutrition solutions that will help them strength, and functional capacity in pre-conditioned older women: A randomized clinical trial. Nutrients. 2018;10(5):1-14. doi:10.3390/nu10050563. Population aging is particularly rapid in the Asia- live stronger, healthier, more active lives. Offering 3 Silva AM, Barbosa DS, Fernandes RR, et al. Effects of Protein Intake Beyond Pacific region, where the UN predicts that one in the full benefits of whey protein, which is superior HabitualIntakes Associated With Resistance Training on Metabolic Syndrome-Related four people will be over 60 by 2050.4 The demand to other protein sources for muscle synthesis in Parameters, Isokinetic Strength and Body Composition in Older Women. J Aging Phys Act. 2019:1-25. doi:10.1123/japa.2018-0370. ® for nutrition solutions to meet their health needs is older people, Lacprodan HYDRO.Rebuild is a 4 United Nations Population Fund, UNFPA (Asia & The Pacific) also growing. The number of new senior nutrition clinically proven solution.” 5 Innova Market Insights, 2020 products containing whey ingredients grew by a Derived from grass-fed cows and made in Denmark, Lacprodan® HYDRO.Rebuild is low-fat, Halal www.arlafoods.com

Seeing is believing: New study provides visible evidence of benefits of Lycoderm™ for skin

NEW CLINICAL RESEARCH SHOWS Lycoderm™ can Affairs, said: “We already knew that Lycoderm™ bring about significant improvements to skin health helps provide nourishment for the skin, building up and appearance. carotenoids like a reservoir of goodness. However, Lycored’s ingestible skincare extract was found seeing is believing and this study shows that to benefit overall skin condition as well as visibly Lycoderm™ can have a remarkable impact on skin boosting radiance and reducing the appearance of appearance as well as health. It’s visible evidence lines and wrinkles. that beauty comes from within, showing how Previous studies have shown that supplemen- supplementation can help consumers achieve tation with Lycoderm™ correlates to a significant an ‘inner glow’ that enables them to feel truly increase in carotenoid levels in the skin and comfortable in their own skin.” improves its resilience to environmental factors such Lycoderm™ is a vegan-friendly blend of tomato as UV rays1. extract and rosemary leaf extract that was devel- However, the new study – a double-blind, oped to provide a holistic skincare foundation. It placebo-controlled trial – is the first to focus on contains lycopene, phytoene, phytofluene and visible beauty parameters2. carnosic acid, which nourish the skin from the As well as measuring skin carotenoid levels, the inside out. researchers assessed the effects of Lycoderm™ The combination of these carotenoids and through photo image analysis, questionnaires and nutrients supports skin health and appearance, expert visual grading of facial wrinkles. helps balance our skin’s response to environmental At the end of the 16-week study, the stress, and supports the maintenance of natural Lycoderm™ group saw a 5.6percent reduction collagen. (p<0.05) in wrinkle severity, while those taking the Lycoderm™ is a plant-based, clean-label placebo saw no significant effect. A similar trend solution that is proven to be bioavailable with a was observed for fine lines. holistic mechanism of action. The vast majority (80.6%) of subjects taking The study was first published in Clinical Lycoderm™ also reported that their skin felt Pharmacology and Biopharmaceutics: https:// smoother. The results were even more pronounced www.omicsonline.org/open-access/effect-of-oral- for dryness, with 90.3% saying their skin felt more supplement-lycopene-on-reducing-the-signs-of- hydrated. skin-ageing.pdf In addition, more than two-thirds (67.7%) of the References: 1 Groten, K. et al. 'Tomato Phytonutrients Balance UV Response: Results from a Lycoderm™ group noticed their skin had a more Double-Blind, Randomized, Placebo-Controlled Study' Skin Pharmacology and even tone, and 64.5% said they had seen an Physiology (2019) 2 Tarshish, E., Hermoni, K. & Schwartz, S.R. 'Effect of oral supplement “Lycopene” on improvement in its brightness. reducing the signs of skin ageing' Clinical Pharmacology and Biopharmaceutics Elizabeth Tarshish, Lycored's Head of Clinical (2020)

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A new double-blind, placebo-controlled, published study shows antioxidant Robuvit® boosts physical and mental recovery following surgery

A NEW DOUBLE-BLIND, placebo-controlled study control group using a questionnaire and biochemi- Robuvit® French oak wood extract is a power- published in the Journal of Nutrients found cal analysis of blood samples. Evaluations took place ful natural antioxidant shown in numerous clinical that supplementation with Robuvit®, a powerful before supplementation began, and again after studies to support convalescence and improve antioxidant extract derived from French oak wood, three and seven days, and four and eight weeks energy and mood. A peer-reviewed study con- improves general health, mood and social func- after surgery. ducted and published in 2018 showed that supple- tioning of patients within four weeks of a surgical “The recovery period following an invasive menting with Robuvit® can help improve fatigue in procedure. Nearly 50 million outpatient surgical surgery is critically important. It can affect a medical convalescence. procedures are conducted every year in the U.S. patient’s mental health, and their ability to perform “These findings are promising for women who according to the CDC1, and as many as 15%2 of daily physical tasks as their body recuperates. Nearly have undergone a hysterectomy procedure and for emergency surgeries can lead to complications in 15%4 of patients experience post-operative compli- any post-surgery patient,” says Dr. Pescatore. “I’m recovery. cations during the recovery period and studies5 particularly encouraged by the improvement of New research shows the benefits of supple- show significantly higher risk of depression for oxidative stress levels for participants who supple- menting with Robuvit® to support medical conva- women who have undergone this surgery,” said mented with Robuvit®. Oxidative stress is the lescence of post-surgery patients, with notable renowned family physician and nutritional health body’s response to an imbalance of antioxidants improvements after four weeks expert Dr. Fred Pescatore. “This study showing and free radicals which can be triggered by May 13, 2020 A new double-blind, placebo- evidence that Robuvit®, a natural antioxidant, can inflammation from a surgical procedure. High levels controlled study published in the Journal of support that recovery, including the mental health of oxidative stress can cause the body to take longer Nutrients found that supplementation with aspects, represents a step forward for post- to recover and can affect mood. The improvement Robuvit®, a powerful antioxidant extract derived operative recovery.” in the Robuvit® test group shows that this antioxi- from French oak wood, improves general health, Following four weeks, participants in the dant helps the body recover more efficiently and mood and social functioning of patients within four Robuvit® supplementation test group showed sig- supports mood.” weeks of a surgical procedure. Nearly 50 million out- nificantly improved physical and mental health re- “I’ve treated post-op patients throughout my patient surgical procedures are conducted every covery compared to the placebo test group, career, and I know how difficult recovery can be and year in the U.S. according to the CDC1, and as including: how long it can extend. These findings bear further many as 15%2 of emergency surgeries can lead to • 18.1% improvement of general ability to perform exploration given what they represent for millions of complications in recovery. physical tasks (compared to 3percent decline in patients,” said Dr. Pescatore. This new research was conducted on 66 female the placebo group) This study builds upon a body of research patients who had just undergone hysterectomy • 17.5% improvement in ability to take part in social supporting Robuvit®’s antioxidative properties to procedures. Study participants supplemented with activities (compared to 7.4percent decline in the combat oxidative stress and its benefits for energy, 300mg of Robuvit® daily for a period of eight weeks. placebo group) mood and convalescence. To review clinical research A hysterectomy is a surgical procedure to remove a • 12.5% improvement of energy and mood (com- and additional information on Robuvit®, visit woman’s uterus and may be medically necessary for pared to 2.3percent improvement in the placebo www.robuvit.com. women with risks of certain types of cancer, chronic group) Horphag Research is the exclusive worldwide pelvic pain or serious complications during In addition, after eight weeks of supplementa- distributor for Robuvit®, French oak wood extract. childbirth. According to the National Women’s tion, analysis of blood samples showed significant Robuvit® is a registered trademarks of Horphag Health Network, hysterectomies are the second reduction of oxidative stress levels in participants Research. For more information, visit www.robu- most commonly performed surgical procedure for who supplemented with Robuvit® (6.3percent vit.com. women in their reproductive years3. In a recent increase of oxidative stress in the Robuvit® test References: 2 study conducted by Mayo Clinic , women who group compared to 57% increase in the placebo 1 CDC: https://www.cdc.gov/nchs/data/nhsr/nhsr102.pdf underwent surgery for a hysterectomy were nearly group). Also, the enhancement of MMP-9, an 2 JAMA Surgery: https://jamanetwork.com/journals/jamasurgery/fullarticle/2516780 3 National Women’s Health Network: https://www.nwhn.org/hysterectomy/ twice as likely to develop depression than women enzyme involved in the degradation of the extra- 4 Reuters Health: https://www.reuters.com/article/us-health-surgery-satisfaction/ who did not undergo this procedure. cellular matrix, was significantly reduced compared patient-satisfaction-not-influenced-by-surgery-complications-idUSKCN1NR23F 5 Mayo Clinic: https://newsnetwork.mayoclinic.org/discussion/study-finds-women- Researchers compared results to a placebo to placebo. at-greater-risk-of-depression-anxiety-after-hysterectomy/

DuPont Nutrition & Biosciences announces research collaboration with Rutgers Universityin the USA

DUPONT NUTRITION & BIOSCIENCES has announced comfort while undergoing cancer treatment. improved health and wellness. Staying at the fore- a research collaboration in microbiome science with “We are privileged to be working with Dr. front of biotechnology innovation, HMV is designed the Center for Advanced Biotechnology and Martin J. Blaser, Dr. Fang Liu and their team at to accelerate product development to complement Medicine (CABM) at Rutgers University in the USA. Rutgers on a project targeted at improving patient its existing portfolio and build on DuPont’s strong The two-year research partnership will focus on care for those undergoing chemotherapy, and to expertise in prebiotics, microbes, proteins and improving the benefit/risk ratio of chemotherapy combine world-class science from Dr. Blaser and his enzymes use for human health. by decreasing gut inflammation caused by team with our broad portfolio of microbes to “We are delighted to further develop our chemotherapy to potentially improve response further advance the understanding of the intake of relationship with DuPont for the benefit of human rates through modulation of the microbiome. beneficial microbes on human health,” said health,” said Martin J. Blaser, director of the Center Recent studies demonstrate that microbiome plays Sébastien Guéry, Ph.D., Human Microbiome Venture for Advanced Biotechnology and Medicine. “The an important role in gut inflammation and that oral leader, DuPont Nutrition & Biosciences. interaction of the microbiome with cancer is an intake of oncology drugs can induce enterocolitis. The DuPont Human Microbiome Venture (HMV) important frontier, with important leads already. Our As such, the administration of beneficial microbes was launched in 2017 to spearhead development project is aimed to discover new ways to improve may lead to improving overall patient care and of next-generation microbiome solutions for cancer therapies.”

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Jennewein publishes new results of the norovirus- inhibiting effect of complex oligosaccharides

JENNEWEIN BIOTECHNOLOGIE GMBH has of Jennewein Biotechnologie. “Our company has rides, which mimic the virus receptors even more announced the publication of the latest results from been working for many years on the development closely, allows us to significantly improve this its norovirus research program in the Journal of of HMOs and other complex carbohydrates that protective effect.” Biotechnology. Breast-fed infants are less likely than bind to norovirus and prevent infections.” bottle-fed infants to contract norovirus Dr Katja Parschat, Co-Head of R&D at About human milk oligosaccharides infections, and earlier work has indicated a link Jennewein Biotechnologie, adds: “Complex HMOs are complex sugar molecules that are between this protective effect and human milk oligosaccharides such as HMOs can mimic the only present in breast milk. Excluding water, they oligosaccharides (HMOs). In our previous study, we structure of the virus’s natural receptor on human are the third most abundant constituent of human found that the most abundant HMOs, namely cells, coating the virus and preventing it from milk after fats and lactose. More than 200 2′-fucosyllactose (2′-FL) and 3-fucosyllactose (3-FL), interacting with its targets. We demonstrated this structurally distinct HMOs have been identified. can directly inhibit certain serotypes of norovirus by ability for 2′-FL and 3-FL in our previous study. But The most abundant HMO is 2′-FL, which is blocking interactions between the virus and its the development of more complex oligosaccha- produced by about 80% of all lactating mothers and natural receptor. In this latest study, is present at concentrations of up to 3 g/L. entitled “Biotechnologically produced HMOs, and 2′-FL in particular, have a fucosylated oligosaccharides inhibit the positive impact on infant development by binding of human noroviruses to their promoting the growth of beneficial natural receptors”, we extended our work microorganisms and inhibiting the growth to include additional HMOs such as lacto- of pathogens, directly and indirectly N-fucopenatose I and even more complex preventing colonisation. Jennewein oligosaccharides. Biotechnologie launched its 2′-FL product “With more than 600 million infections onto the global baby food market in 2015, and 200 000 deaths per year and no treat- and several infant milk formulas around ment available, norovirus is definitely a the world now contain 2′-FL (e.g., Abbott global health problem, and a particular Similac, Danone Aptamil ProFutura). threat to infants, small children and the - elderly,” states Dr Stefan Jennewein, CEO www.jennewein-biotech.com Affron® saffron targets teen stress TEENAGERS ARE ONE OF the most vulnerable Affron is the first saffron extract (Crocus sativus targets for stress due to the COVID-19 crisis and L.) clinically studied on adolescents. In a random- among the hardest hit from a mental health stand- ized, double-blind, placebo-controlled study of point. Parents are seeking natural, holistic solutions adolescents aged 12-16 years with mild-to- for mental health for their children and themselves. moderate symptoms, affron, when taken over an Pharmactive Biotech, S.L., can now offer its affron®, 8-week period, improved anxiety and depressive all-natural saffron extract as a holistic solution for symptoms in the subjects. participating in class. mental health for teens and other age groups. “Affron possesses a potent antioxidant and “It's hard enough being a teenager on a anti-inflammatory impact, which not only could good day and the social isolation is making it even Rising mental health risks for teenagers help balance key neurotransmitters levels, such as harder,” says Julia Díaz Sáez, Head of Marketing for brought on by extended isolation serotonin and dopamine, but also fights the oxida- Pharmactive. “There is no magic solution. It is • Results from a study of 500 participants in the tive stress produced by anxiety and stress in important to help teens cope with anxiety and University of Oxford’s “Achieving Resilience During the brain,” explains Alberto Espinel, Manager of stress by encouraging them to work out regularly, COVID-19” (ARC) show that more than one-third Strategic R&Din Active and Functional Natural keep a routine, play music, and show them love and of 13 to 18-year-olds reported high levels of Ingredients for Pharmactive. “Unfortunately, support. Combined with daily consumption of loneliness. The study also uncovered evidence of investigations into the use of herbal and nutraceu- affron saffron, it can help pave the way to ease loneliness as predicting depression and possible tical agents for youth are limited. However, they stress and anxiety in teens.” anxiety in the future. 1 carry significant potential that has yet to be The clinical studies on adolescents indicate that • In a recent survey by the UK-based Young Minds realized. This gap in scientific exploration is what Pharmactive’s affron could present a safe and highly movement of 2,111 young people with a history inspired our study of affron with adolescents.” compelling option for helping teens and even of mental health problems, more than half younger children cope with crisis events, especially reported that the pressure brought on by the Teen Help Line where access to in-person psychological therapy is COVID-19 crisis made their mental health “a bit Adolescents typically have a heightened restricted. This pure ingredient exhibits the lowest worse,” and nearly one third reported that it made reactivity to stress, thought to be the result of dosage threshold on the market — just 28mg per their mental health “much worse.”2 hormonal fluctuations and changes in brain devel- day — due to its high bioavailability and rapid one- • A study by UNICEF, Australia, revealed that the opment. The teenage years are already difficult, but hour average absorption rate. threat of the coronavirus and the associated lock- COVID-19 has intensified the situation. Due to References: 1 https://www.euronews.com/2020/06/03/lockdown-loneliness-is-going-to-have-a- down is damaging the well-being of Australian school closures and cancelled extracurricular worse-long-term-impact-on-teenagers-mental-health-v teenagers, with fewer than half saying they are activities, many teens are missing out on some of 2 https://youngminds.org.uk/media/3708/coronavirus-report_march2020.pdf 3 https://www.smh.com.au/lifestyle/life-and-relationships/teenage-girls-more- “coping well.” Almost half of young people report the biggest moments of their lives, such as stressed-and-anxious-under-lockdown-than-boys-20200515-p54tg8.html that COVID-19 has increased their stress and sports events, proms, etc., in addition to basic anxiety.3 everyday moments, like chatting with friends and www.pharmactive.eu

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Global FATitudes™ study finds consumers closely monitor fats,oils in packaged food MOST CONSUMERS (68%) ACROSS the world report to purchase expiration date and ingredients lists are most often closely monitoring the type and amount of fat and • How often consumers read labels differs by consulted when deciding what to eat, labels and oil in their packaged food, according to a recent geography. Chinese consumers pay the most health claims are also highly influential on food global FATitudes study from Cargill. The study attention (89%), and German consumers monitor purchasing decisions,” said Webster. “Cargill’s confirmed that consumers track what goes into the least (48%) FATitudes survey looks at similar perceptions and their bodies by closely reading labels of packaged • Nearly two-thirds (61%) of U.S. consumers report behaviors specifically related to fats and oils, this foods, with fat and oil type as strong purchase avoiding certain fats or oils, and among those who time from an international vantage point. These consideration factors. rank as “clean-label seekers,” 83% report avoiding global perspectives shed light on important FATitudes is a study conducted by Cargill each certain fats or oils, like saturated and trans fats differences between countries and provide critical year to learn more about consumers’ awareness, • Olive oil tops the list in every country for impact insights into how people around the world think perceptions and behaviors around fats and oils on purchase and perceptions of healthfulness in about two all-important questions: ‘What should I found in packaged foods, and to help inform the packaged foods, followed by fish and avocado oils eat, and why?’” future of food innovation. This year, approximately • A vast majority of global consumers, 93%, were 6,600 primary household grocery shoppers were aware of omega-3s, which is an important nutrient The FATitudes study aims to deliver insights surveyed in 12 countries including the United with many health benefits some consumers don’t to drive food innovation States, Germany, China, Brazil, the United Kingdom get through their typical diet The results from FATitudes help Cargill food and more. innovators understand what consumers want, “This type of research is important because it Consumers influenced by claims on enabling them to develop innovative products that gives Cargill and our customers a guidepost for our packaged food: deliver on changing needs and desires. By gathering innovation efforts,” said Nese Tagma, Managing • Most consumers are checking labels for fat-related consumer-based insights, strategic product devel- Director of Strategy and Innovation for Cargill’s claims (fat-free, low fat, etc.) on packaged foods, opment can take shape more effectively. global edible oils business. “As consumers’ attitudes and 54% say such a claim makes them more likely "Food is becoming increasingly personalized; toward fats and oils have shifted in recent years, we to purchase consumers are basing their purchasing decisions on know they’re interested in consuming healthy • Consumers in Russia (76%), China (62%) and Brazil specific ingredients. At the same time, society is amounts of oils. We’re able to offer a broad port- (61%) indicate they are more likely to purchase a driving food ingredient companies to develop more folio of fat and oil solutions, including our Clear product with a sustainability claim options for health-conscious consumers. Using Valley® line, which has a canola-based product with • In most countries, an organic certification on a consumer insights helps us innovate in ways that lower saturated fat. This research is vital to guide label is more impactful on purchasing decisions balance the societal pressures with individual our thinking on whether to revitalize tried-and-true versus a non-GMO verification preferences to create healthful, sustainable products or develop a new frying oil to adapt to Allison Webster, Director of Research and and cost-effective products,” said Florian changing tastes and health options.” Nutrition Communications for International Food Schattenmann, CTO and vice president of Here are some key findings from the study: Information Council (IFIC), emphasized the impor- Innovation and R&D, Cargill. • A majority of global consumers report the amount tance of this global perspective. For more information on FATitudes, contact of fat (70%) and type of oil (67%) are important “IFIC’s U.S.-based consumer research consis- [email protected]. factors when determining which packaged foods tently shows that while nutrition information,

Stability studies reveal there’s more than meets the eye for Lycored’s natural colour ingredients for meat-free alternatives

LYCORED, A GLOBAL LEADER in lycopene-based iron oxide relative to process stability and ingredients that can handle the processing condi- colour and taste-enhancing ingredients for food authentic, appetizing hues tions for plant-based proteins substitutes. and beverages, recently published the results of • Real time and accelerated shelf life tests proved “Lycored’s lycopene-based colours are a two-colour plant-based meat alternative stability colour stability of ham slices to meet standard natural first choice for many of today’s most studies. shelf life and beyond popular meat substitutes,” notes Lippert, conclud- The studies found that the company’s range of • Lycopene-based colours in sausages, provide a ing: “Plant-based meat alternatives are vying for the super-stable colours deliver authentic meat like range of colours with authentic appearance be- top of the vegetarian product food chain but they coloration with long last stability, in plant-based fore and after cooking can’t get there unless ingredients are clean, able to meat alternatives. Commenting on the results, Christiane Lippert, withstand intensive processing and assure colour Focusing on plant-based deli ham slices and Head of Marketing (food) at Lycored said, “Global stays true. Our study data confirms lycopene-based sausage-style encased meats, Lycored’s scientists consumption of plant-based foods is growing, colours have everything the industry needs to make put their portfolio of all-natural, lycopene-based especially meat-free alternatives designed to look products in this category a success.” colours to the test comparing them to two and taste like foods in segments like deli ham and Lycored’s broad range of hues provide a industry standard all-natural colour alternatives: sausages. As part of these new dietary trends, far-reaching palette that makes it easy for food beet and iron oxide. people are increasingly searching for alternatives to manufacturers to find the intensity and colour they Results revealed that Lycored’s colours are meat in their traditional diets and this includes a need to meet tough stability criteria. Lycored’s ready for the rigors of plant-based food processing, growing number of so-called meat reducers or HueFinder is a convenient way to learn more about as well as meeting consumers’ demands for an ‘flexitarian’ consumers.” how Lycored’s colours can help with your plant- authentic look and taste. Highlights of Lycored’s To appeal to the masses plant-based meats based meat application. studies revealed: must be clean label yet look, feel and taste just like Click here to find out more: https://www. • For both ham slices and sausages Lycored’s the real thing, before and after cooking. This is lycored.com/huefinder/. lycopene based colour outperformed beet and challenging food engineers to find colour

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Activ’Inside finalizes a €16.3M grant for the Silver Brain Food Project

ACTIV’INSIDE, AN SME specialized in developing and validated for their preventive actions against Academic and industrialpartners – the producing active plant ingredients for the Health cognitive decline. guarantee of scientific objectification Nutrition industries, announces the launch of the • Develop digital nutritional coaching solutions and This project is certified by the Agri Sud-Ouest Silver Brain Food project. This program is carried out personalized non-stigmatizing follow-up services Innovation, Vitagora and Systematic competitive- in collaboration with the University Laboratories of for individuals and professional caretakers to ness clusters and is supported by the Silver Valley NutriNeuro and Bordeaux Population Health, as well promote high neuro-nutritional density diet . cluster. It calls on the synergy of skills from both as a consortium of industrial companies. Silver Brain On top of these groundbreaking innovations, industrial and academic partners to ensure Food aims at developing local, personalized the project plans to create a network of neighbor- scientific objectification. solutions, products and services to promote a hood shops offering products and services to The project’s industrial partners: nutrient-rich diet, essential for brain health, to the promote elderly people’s well-being at home. • The SME Activ’Inside (project leader) which elderly, and therefore prevent cognitive decline specializes in developing, producing and market- This research program has a total budget of A project built on promising results ing active plant ingredients (from grapes and €16.3M, including €9.3 million from the Invest- The launch of the Silver Brain Food project is a saffron) for the Health Nutrition industries, ments for the Future Program (PIA) operated by continuation of the research work initiated by especially the field of neuro nutrition Bpifrance. Activ’Inside: • EC6 is an expert in catering and hospital and • A first study based on epidemiological data geriatric nutrition Responding to a major public health issue conducted by the U1219 Bordeaux Population • GoodMix is an expert in digital nutritional coach- While age related cognitive decline is a normal Health research center (Joint Research Unit (UMR) ing solutions part of the aging process, it can lead to a higher INSERM-University of Bordeaux) and Activ’Inside In addition to these partners, there is a user cognitive impairment or disease such as dementia, demonstrated that people who consume high committee which will bring together companies its main form being Alzheimer’s (around 70% of quantities of a combination of polyphenols, likely to test the solutions that will be developed cases of dementia). This disease currently has no including grapes, had a 50% reduction of the during the project. The first industrial ETI in the food cure and frequently requires treatment by special- incidence of dementia and Alzheimer’s disease! industry has already joined this committee. ized facilities, representingan estimated cost of • Furthermore, a consortium of industrial and The project’s academic partners are: 23 billion euros per year in France. Activ’Inside academic partners led by Activ’Inside and the • The NutriNeuro Joint Research Unit (UMR) started the Silver Brain Food project to respond to NutriNeuro laboratory (UMR INRAE/University of (National Institute for Agronomic Research and this major economic and public health issue. Bordeaux/INP) launched a research project. the Environment INRAE, University of Bordeaux Conducted between 2011 and 2018, this and Bordeaux INP) which specializes in integrated Prevent cognitive decline through a high project highlighted the clinical effectiveness of nutrition and neurobiology neuro-nutritionaldensity diet Memophenol™, a formulation of polyphenols • The Joint Research Unit (UMR) U1219 “Bordeaux Silver Brain Food is a research project that aims from grapes and blueberries developed by Population Health” (National Institute of Health at preventing cognitive decline of elderly people Activ’Inside, on the normal cognitive decline of and Medical Research INSERM-University of thanks to a diet rich in nutrients for brain health. elderly people. These results were also deemed Bordeaux) which specializes in epidemiology of Drawing on the technical, scientific and industrial promising by a leading international medical nutrition and aging expertise of the 5 members of the consortium, journal (JAMA) and a first health claim on Silver Brain Food plans to: Memophenol™ which was delivered by health More about ACTIV’INSIDE • Develop extracts rich in neuro phytonutrients authorities in South Korea in late 2019. Based in Bordeaux area, Activ’Inside is an obtained through an innovative industrial Based on these promising first results, independent foodtech company specialized in the eco-process. members of Silver Brain Food are now planning to development, production and marketing of • Develop a range of high-density neuro-nutritional obtain new claims on cognitive decline prevention natural active ingredients (mainly from grape and foods standardized in nutrients scientifically within 5 years. saffron) for the Health Nutrition Industries.

First review article on Health Effects of Wax Ester Omega-3s

A RECENT REVIEW ARTICLE BY Schots et al., Head of Science in Calanus AS, Alice Marie 2 diabetes. published in Frontiers in Pharmacology, investigates Pedersen, PhD, says: “This publication is the first Dr. Pedersen concludes: “Stearidonic acid is also how the different constituents of Calanus® Oil can comprehensive review that evaluates the different extremely interesting, and it is likely that this special contribute to the prevention of obesity-induced bioactive constituents of Calanus® Oil. Even if there fatty acid, as a part of the wax ester molecule, could low-grade inflammation and the associated is still much to discover, there is already exisiting explain many of the benefits we have observed in metabolic disturbances. Calanus® Oil is a natural oil knowledge on for instance policosanols and research and among consumers“. derived from the 1-year copepod Calanus monounsaturated fatty acids, which are associated Calanus® Oil is an omega-3 rich oil, where the finmarchicus. In addition to having the unique wax with the mediterranean diet“. fatty acid s special chemistry gives additional ester form, Calanus® Oil is not refined and therefore The researchers also conclude that the the wax benefits in the metabolic health area. Recent contains a broad range of nutrients. esters likely act as natural delayed release molecules, research has shown a favorable impact on body The publication summarizes knowledge of thereby facilitating transportation of fatty acids to composition, insulin sensitivity and heart pumping common omega-3 fatty acids like EPA and DHA, and the GPR120 receptors. The fatty acids act as potent efficiency. Calanus® Oil is currently being sold in in addtion how stearidonic acid, monounsaturated stimulators of the GPR120 receptor, which is Europe and North America, with several regulatory fatty acids, policosanols and astaxanthin can associated with reduced inflammation, improved approval processes ongoing in other markets. contribute to the metabolic and inflammatory isulin sensitivity and enhanced glucose uptake. health in a favorable way. GPR120 is a target for treatment of obesity and type www.calanus.no

88 Innovations in Food Technology | August 2020 | www.innovationsfood.com GEN NEWS STUDY:TESTING 12/8/20 16:26 Page 7

ADM supports clinical trial into Effects of Probiotic Supplements for COVID-19 patients in hospital care

ADM AND HOSPITAL DE SAGUNTO, one of the on the most potentially suitable live microbial strains solutions to challenging health and wellness largest medical centers in the Valencia region, to use during the trial, and to invite the team to concerns.” said Francisco Climent, ADM’s Health & recently announced a partnership for a clinical trial collaborate with Hospital de Sagunto in the design Wellness managing director, EMEAI. into the effects of using a food supplement of the clinical trial. “More than 75 patients admitted to the containing live microbial strains to promote gut Gasteel Plus, a live microbial probiotic-based hospital with COVID-19 have already been enrolled microbiome balance and help improve health food supplement marketed by Laboratorios Heel in the trial, and are giving regular blood, stool, urine functions related to outcomes for COVID-19 España, S.A.U. and formulated using ADM probiotic and nasopharyngeal exudate samples to measure patients in high-risk groups. strains, as well as essential nutrients vitamin D, changes in immune parameters and other factors On 18th March Dr Xavier Cortés, gastroenterol- selenium and zinc, was selected in this interven- such as viral load,” said Dr. Cortés. “Using these ogist at Hospital de Sagunto, communicated with tional trial. The product has been administered to indicators, we will assess the efficacy of Gasteel Plus medical staff in China who had observed that many patients with COVID-19 symptoms, as well as to as an adjunct solution to support the health of the COVID-19 patients had exhibited abnormal changes healthcare personnel at the hospital who fall into elderly population, who are especially vulnerable to in their gut microbiome. The reports indicated high-risk groups (the over 60s or those with chronic this viral infection.” that a significant percentage of infected people diseases), at Hospital de Sagunto, to strengthen “In the coming weeks, the aim is to expand the experienced gastrointestinal problems in the early their gut microbiota. The three ADM probiotic strains reach of this study to 100 patients, while simulta- stages of the illness, similar to the trend he was contained in Gasteel Plus, namely Bifidobacterium neously exploring the potential beneficial effects of observing in Spain. This trend is particularly prevalent longum CECT7347, Bifidobacterium animalis subsp. additional ingredients such as botanical extracts, oils in elderly patients, who tend to have lower levels of lactis CECT9950 and Lactobacillus rhamnosus and fibers in separate pre-clinical studies,” Climent beneficial bifidobacterial content in their gut CNCM-I4036, as well as essential nutrients vitamin continued. “Through this research, we hope to microbiome. Following his assessment, a decision D, selenium and zinc, have been shown in pre-clin- create more unique blends of our health and was made that an interventional trial should be ical studies to exert anti-inflammatory, antioxidant wellness ingredients that may help support the conducted to evaluate the effects of providing and other immune-supporting effects. health of those for whom COVID-19 poses the standard medication to elderly COVID-19 patients, “Thanks to the common efforts of three teams greatest threat.” along with a live microbial supplement to help from the Hospital de Sagunto, Heel Laboratories and To learn more about ADM’s wider activities to support gut health and immune function. Dr Cortés ADM Biopolis, we were able to start the trial at the support the work of healthcare professionals contacted ADM’s scientific team for expert advice end of March and we are discovering innovative during the coronavirus crisis, go to www.adm.com

Vitamin K2 lowers coronary heart disease risk

THE BRITISH MEDICAL JOURNAL recently published confirming vitamin K2’s important health benefits, year food frequency questionnaire. During a an observational study that examined the associa- showing in human studies with healthy2 and patient median follow-up time of 11 years, we documented tion between intakes of vitamins K1 and K2 and participants that the progression of hardening of 112 incident CHDcases. incidence of coronary heart disease (CHD). The the arteries can be halted and even regressed with In the adjusted analyses, there was no associa- 11-year Norwegian community-based prospective daily supplementation of MenaQ7 Vitamin K2,” says tion between intake of vitamin K1 and CHD cohort did indeed show a link between K2 intakes Dr. Vik, noting that this study builds on the body of (HRQ4vsQ1 = 0.92 (95% CI 0.54 to 1.57), p for trend and a lower risk of subsequent CHDevents, building evidence linking vitamin K status to health concerns 0.64), while there was a lower risk of CHDassociated the evidence that K2’s impact on calcification can such as peripheral arterial disease (PAD)3, coronary with higher intake of energy-adjusted vitamin K2 greatly improve health outcomes. calcification4, dementia5, vascular stiffness in chronic (HRQ4vsQ1 = 0.52 (0.29 to 0.94), p for trend 0.03). According to “Association of dietary vitamin K kidney disease patients (CKD)6 and more. “The Further adjustment for potential dietary and risk of coronary heart disease in middle-age common link is calcification and the need for confounders did not materially change the associ- adults: the Hordaland Health Study Cohort”1, the adequate vitamin K2 intakes to inhibit this in our ation for K1, while the association for K2 was slightly role of vitamin K in the regulation of vascular circulatory system and tissues. Due to its very attenuated (HRQ4vsQ1 = 0.58 (0.28 to 1.19)). calcification is established, and that patients with molecular structure, vitamin K2 can move beyond Given the limited number of epidemiological both medial and intimal calcification have a higher the liver to support other systems of the body, such studies, and the fact that dietary vitamin K sources cardiovascular risk when compared with similar as the bones and vasculature, where K1 cannot. and content differ between countries, the patients without calcification. Therefore, an inverse There remains a great deal of confusion that K1 researchers noted that further research is association between vitamin K intake and coronary supports both bone and heart health, and this warranted. heart disease (CHD) could be expected. The paper helps to identify the difference between the purpose of the current study was to evaluate the two in that K1 is not linked to cardiovascular health, References: 1 Haugsgjerd TR, Egeland GM, Nygård OK, et al. Association of dietary vitamin K and association between intake of both K1 and K2 and whereas K2 is linked to both. risk of coronary heart disease in middle-age adults: the Hordaland Health Study subsequent CHDevents among community-living “These results mirror what we have seen in Cohort. BMJ Open 2020;10:e035953. doi:10.1136/bmjopen-2019-035953. 2 Knapen MHJ, Braam LAKJLM, Drummen NE, Bekers O, Hoeks APG, Vermeer C. middle-aged adults in Norway. epidemiological studies, where populations who Menaquinone-7 Supplementation Improves Arterial Stiffness in Healthy Post- The researchers concluded “a higher intake of consume a lot of dietary Vitamin K2 have healthier menopausal Women. A Double-Blind Randomised Clinical Trial. Thromb Haemost. 2015 May;113(5):1135-44. vitamin K2 was associated with lower risk of CHD, hearts and more flexible arteries,” Vik adds. “Recog- 3 Vissers LET, Dalmeijer GW, Boer JMA, Verschuren WMM, van der Schouw YT, while there was no association between intake of nition of vitamin K2’s benefits as strong and signif- Beulens JWJ. The relationship between vitamin Kand peripheral arterial disease. vitamin K1 and CHD.” icant elucidated inhibitor of vascular and soft tissue Atherosclerosis 252 (2016) 15e20. 4 Wei FF, Thijs L, Cauwenberghs N, Yang WY, Zhang ZY, Yu CG, Kuznetsova T, et al. The paper is significant because it not only adds calcification is one of the core reasons a separate Central Hemodynamics in Relation to Circulating Desphospho-Uncarboxylated to the growing body of evidence substantiating RDI should be established.” Matrix Gla Protein: A Population Study. J Am Heart Assoc. 2019;8:e011960. DOI: 10.1161/JAHA.119.011960. vitamin K2 as a cardiovascular-support nutrient, Researchers followed participants (2,987 5 Cui C, Sekikawa A, Kuller LH, Lopez OL, Newman AB, Kuipers AL, Mackey RH. according to NattoPharma Chief Medical Officer Dr. Norwegian men and women aged 46-49 years) in Aortic stiffness is associated with increased risk of incident dementia in older adults. J Alzheimer’s Dis. 2018;66(1):297-306. Hogne Vik, but it helps to clarify the confusion that the community-based Hordaland Health Study from 6 Thamratnopkoon S, Susantitaphong P,Tumkosit M, Katavetin P,Tiranathanagul K, “vitamin K is vitamin K,” also confirming the need 1997 - 1999 through 2009 to evaluate associations Praditpornsilpa K, Eiam-Ong S. Correlations of Plasma Desphosphorylated for a K2-specific recommended daily intake (RDI) between intake of vitamin K and incident (new Uncarboxylated Matrix Gla Protein with Vascular Calcification and Vascular Stiffness in Chronic Kidney Disease. Nephron. 2017;135(3):167-172. “NattoPharma has driven the research onset) CHD. Baseline diet was assessed by a past-

Innovations in Food Technology | August 2020 | www.innovationsfood.com 89 GEN NEWS STUDY:TESTING 12/8/20 16:26 Page 8

CLINICAL STUDY RESULTS - 7 PAGE SECTION

Proven ingredient for sports performance boost

A RECENTLYPUBLISHED randomised, double-blind, determine an optimal supplementation strategy. crossover study found that AstaReal® natural A major strength of this new study was the astaxanthin helps improve sporting endurance and randomised crossover design, as this allowed each fat metabolism.1 It is the first trial to demonstrate participant to act as their own control, minimising an increase in whole-body fat metabolism and a the potential impact subtle differences in corresponding reduction in respiratory exchange participant characteristics and individual responses ratio during endurance exercise in those supple- to astaxanthin could have upon the outcome menting with astaxanthin. Findings from previous variable. studies have shown that the microalgae-derived Andie Long, Marketing & Sales Manager at nutrient can boost muscle power, fight fatigue, AstaReal, says: “There is a growing body of evidence counteract inflammation and reduce lactic acid Following astaxanthin supplementation, the regarding natural astaxanthin’s benefits for build-up, making AstaReal® astaxanthin an time to complete the exercise improved by endurance, focus, power and muscle health. People important ingredient for sports nutrition and dietary 1.2 ± 1.7%, from 70.76 ± 3.93 min in the can get support for all of these issues and more, in supplements. placebo condition to 69.90 ± 3.78 min in the just one astaxanthin-based supplement. Whether The new study aimed to investigate whether astaxanthin condition. Additionally, whole-body fat they are capsules, sachets or functional drinks, the short-term, seven-day supplementation with metabolism rates were significantly higher and the possibilities for developing natural astaxanthin astaxanthin could improve exercise performance respiratory exchange ratio was significantly lower at products for sports – and also in combination with and metabolism during a 40 km cycling time trial. the 39–40 km stage, following astaxanthin supple- other key ingredients – are vast.” Twelve amateur cyclists were recruited. They mentation and compared with the placebo. The received either 12 mg AstaReal® astaxanthin or an researchers concluded that astaxanthin provided an 1 D.R. Brown,A.R.Warner, S.K. Deb, L.A. Gough, S.A. Sparks, L.R. McNaughton:The effect of astaxanthin supplementation on performance and fat oxidation during a appearance-matched placebo daily for seven days. ergogenic benefit to the athletes’ performance and 40_km cycling time trial. Journal of Science and Medicine in Sport. 3 July 2020. On day seven of supplementation, the participants enhanced their whole-body fat metabolism in the https://doi.org/10.1016/j.jsams.2020.06.017 completed a 40_km cycling time trial on an final stages of this endurance-type exercise. To ergometer, with indices of exercise metabolism enable the successful application of astaxanthin in www.astareal.com measured throughout. sports nutrition, future studies should aim to

Euromed’s ABAlife® fig extract increases muscle metabolism

A RECENTLYPUBLISHED study by the NIMML systemic inflammation in patients with chronic Institute and Biotherapeutics (Blacksburg, VA, US) metabolic diseases. The researchers are planning to found that Euromed’s ABAlife® fig extract promotes advance ABA to Phase II clinical trials in prediabetic glucose tolerance and insulin sensitivity while and type 2 diabetes patients later this year. decreasing obesity related systemic inflammation in “This study is the culmination of decades of mice.1 The proprietary fig extract is purified using a research regarding how ABA exerts its antidiabetic patent-pending carefully controlled process to and anti-inflammatory properties, and the achieve a high, standardised ABA content. validation of LANCL2 as the molecular target for ABA © iStock_piola ABA is a phytohormone found in fruits as well as in skeletal muscle,” said Dr Josep Bassaganya-Riera, vegetables and is also produced in mammals. In one of the authors. “We already validated the safety scientists concluded unanimously that ABAlife® is humans and mice, lanthionine synthetase C-like and tolerability of fig extract-derived ABA in a Phase recognised as safe under the conditions of intended 2 (LANCL2) has been characterized as a natural I clinical trial in healthy people, during which we use as described in its dossier in a wide range of receptor for ABA. This new study shows that oral demonstrated glycaemic improvements.2 These food and beverage categories. ABA administration improves glucose tolerance, new insights further support the clinical develop- In addition, the American Botanical Council insulin sensitivity and fasting blood glucose in two ment of ABA and take us one step closer to Phase (ABC) welcomes the adoption of fig (Ficus carica) different mouse models of type 2 diabetes by II clinical testing in prediabetic patients.” by Euromed through its Adopt-an-Herb botanical modulating the metabolic activity of skeletal About 84 million of Americans have predia- research and education programme. It is Euromed’s muscle. ABA increases the expression of glycogen betes, which is associated with a high risk of type 2 second adoption through ABC’s programme, with synthase, glucose, fatty acid and mitochondrial diabetes, cardiovascular disease and stroke. There- milk thistle (Silybum marianum) being the first. metabolism genes and increases direct measures fore, there is a crucial need to develop more of fatty acid oxidation, glucose oxidation and effective dietary interventions that can avoid 1 Leber, A., Hontecillas, R., Tubau-Juni, N. et al. Abscisic acid enriched fig extract promotes insulin sensitivity by decreasing systemic inflammation and activating metabolic flexibility in muscle cells from ABA-treated prediabetes and prevent the progression from LANCL2 in skeletal muscle. Sci Rep 10, 10463 (2020). Published 26 June 2020. obese mice. prediabetes to diabetes. 2 Atkinson FS, Villar A, Mulà A, et al. Abscisic Acid Standardized Fig (Ficus carica) ® Extracts Ameliorate Postprandial Glycemic and Insulinemic Responses in Healthy The results of this study postulate ABA as a new Euromed’s ABAlife recently has obtained Self- Adults. Nutrients. 2019 Jul 31;11(8):1757. preventive or therapeutic intervention to improve Affirmed GRAS (Generally Recognized as Safe) glycaemic control and decrease obesity related designation. A GRAS expert panel of independent www.euromed.es

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