Animal Science 434 Significance of DHT Reproductive Physiology • Androgen receptor has a higher affinity for DHT
Embryogenesis of the Pituitary and Sexual • Can get effects with low levels of circulating testosterone Development: Part B • Secondary sex characteristic tissue in the male expresses 5α-reductase
External Genitalia Differentiation
Testis Determining Factor (SRY gene product) No TDF XY Male XX Female
Testes develop Ovaries Develop
Sertoli cells secrete No No AMH anti-mullerian hormone (AMH) Testosterone
AMH causes leydig Degeneration of cells to differentiate Mullerian duct Degeneration of Mullerian ducts Wolffian duct become the oviducts, uterus, cervix Testosterone Dihydrotestosterone and part of the vagina