contents HEART Volume 90 Number 8 August 2004

Formerly British Heart Journal Journal of the British Cardiac Society ...... Editor Deputy Editor Editorials Roger J Hall David Lefroy 827 Will oral antithrombin agents replace warfarin? P R Sinnaeve, F J Van de Werf Commissioning Editor Series Editor, Iain Simpson Education in Heart 829 Glucocorticoid treatment and cardiovascular disease Peter Mills M K C Ng, D S Celermajer Heart: first published as on 1 August 2004. Downloaded from 831 Jesting Pilate, genetic case–control association studies, Associate Editors Adrian P Banning, Eric Butchart, Filippo Crea, David Crossman, and Heart D Crossman, H Watkins John L Gibbs, Bernard Iung, Theresa A McDonagh, 833 The campaign to revitalise academic medicine kicks off Andreas Mu¨gge, Petros Nihoyannopoulos, Catherine M Otto P Tugwell International Advisory Board Barry Maron (USA) ...... Christopher Acar () Thomas Marwick () Felicita Andreotti () William McKenna (UK) Review Fause Attie (Mexico) John McMurray (UK) Philip Aylward (Australia) Bernhard Meier (Switzerland) 835 Multiple pathogenetic mechanisms in X linked dilated Gary Baxter (UK) Neil Moat (UK) cardiomyopathy N Cohen, F Muntoni Jean-Luc Monin (France) George Beller (USA) ...... Martin Bennett (UK) Michael Mullen (UK) Javier Bermejo (Spain) Brad Munt () Cardiovascular medicine Michael Burch (UK) Andrew Murday (UK) Paolo Camici (UK) Stefan Neubauer (UK) 842 Danon’s disease as a cause of hypertrophic Keith Channon (UK) David Newby (UK) cardiomyopathy: a systematic survey P Charron, Alfred Cheng (Singapore) Chris Newman (UK) E Villard, P Se´billon, P Laforeˆt, T Maisonobe, L Duboscq- Andrew Clark (UK) Sunil Ohri (UK) Dudley Pennell (UK) Bidot, N Romero, V Drouin-Garraud, T Fre´bourg, Jacques Clementy (France) P Richard, B Eymard, M Komajda Stuart Cobbe (UK) Philippe Pibarot (Canada) Michael Picard (USA) Lawrence Cohen (USA) 847 Markers of inflammation and multiple complex stenoses Bernard Prendergast (UK) Stuart Connolly (Canada) (pancoronary plaque vulnerability) in patients with non- Prakash Punjabi (UK) Martin Cowie (UK) Shahbudin Rahimtoola (USA) ST segment elevation acute coronary syndromes Nicolas Danchin (France) Margaret Redfield (USA) P Avanzas, R Arroyo-Espliguero, J Cosı´n-Sales, Carlo di Mario (UK) Simon Redwood (UK) G Aldama, C Pizzi, J Quiles, J C Kaski Maurice Enriquez-Sarano John Sanderson (Hong Kong) (USA) 853 Monocyte proinflammatory cytokine release is higher James Scott (UK) Jean-Noel Fabiani (France) Udo Sechtem () and glucocorticoid sensitivity is lower in middle aged Peter Fitzgerald (USA) Ajay Shah (UK) men than in women independent of cardiovascular risk Keith Fox (UK) Man-Fai Shiu (UK) factors P H Wirtz, R von Ka¨nel, N Rohleder, J E Fischer R J Gibbons (USA) L David R Smith (UK) http://heart.bmj.com/ Paul Grayburn (USA) Jordi Soler-Soler (Spain) 859 Use of oral glucocorticoids and risk of cardiovascular Sally Greaves (New Zealand) Giuseppe Specchia (Italy) and cerebrovascular disease in a population based Julian Gunn (UK) Martin St John Sutton (USA) case–control study P C Souverein, A Berard, T P Van Staa, Axel Haverich (Germany) Christodoulos Stefanadis C Cooper, A C G Egberts, H G M Leufkens, B R Walker Gerd Heusch (Germany) (Greece) Pierre Jais (France) William Stevenson (USA) 866 Reliability of N-terminal proBNP assay in diagnosis of Karl Karsch (UK) Kenneth Taylor (UK) left ventricular systolic dysfunction within representative Juan Carlos Kaski (UK) James Thomas (USA) and high risk populations F D R Hobbs, R C Davis, Sanjiv Kaul (USA) Martyn Thomas (UK) A K Roalfe, R Hare, M K Davies Bernard Keavney (UK) Adam Timmis (UK) Bruce Keogh (UK) Eric Topol (USA) 871 Testosterone replacement in hypogonadal men with Robert Kloner (USA) Pilar Tornos (Spain) angina improves ischaemic threshold and quality of life on October 1, 2021 by guest. Protected copyright. Cornelius Kluft (Netherlands) Dimitris Tousoulis (Greece) C J Malkin, P J Pugh, P D Morris, K E Kerry, R D Jones, Michel Komajda (France) Alec Vahanian (France) T H Jones, K S Channer Chim Choy Lang (Malaysia) Panos Vardas (Greece) Gaetano A Lanza (Italy) Sami Viskin (Israel) 877 Rapid access arrhythmia clinic for the diagnosis and Christophe Leclercq (France) Cees Visser (Netherlands) management of new arrhythmias presenting in the Malcolm Legget (New Nozomi Watanabe () community: a prospective, descriptive study J L Martins, Zealand) Hugh Watkins (UK) K F Fox, D A Wood, D C Lefroy, T J Collier, N S Peters Gregory Lip (UK) Gary Webb (Canada) Peter Ludman (UK) Sylvan Lee Weinberg (USA) 882 Local symptoms at the site of pacemaker implantation Thomas Luscher Harvey White (New Zealand) indicate latent systemic infection D Klug, F Wallet, (Switzerland) William Wijns (Belgium) D Lacroix, C Marquie´, C Kouakam, S Kacet, R Courcol Philip MacCarthy (UK) Junichi Yoshikawa (Japan) 887 Relation between different methods for analysing ST Aldo Maggioni (Italy) Editor: British Medical Journal segment deviation and infarct size as assessed by Instructions to authors positron emission tomography W J Desmet, Full instructions are available online at www.heartjnl.com/ L V Mesotten, A F Maes, H P Heidbu¨chel, misc/ifora.shtml L A Mortelmans, F J Van de Werf If you do not have web access please contact the editorial office: Heart 893 Evaluation of aortic stenosis by cardiovascular 9 Fitzroy Square magnetic resonance imaging: comparison with London W1T 5HW, UK established routine clinical techniques C Kupfahl, Telephone +44 (0) 20 7383 4006 M Honold, G Meinhardt, H Vogelsberg, A Wagner, Fax +44 (0) 20 7388 0323 H Mahrholdt, U Sechtem Email [email protected] ...... Subscription information See p iv Interventional cardiology and surgery Copyright 902 Renal function and long term mortality after unstable E 2004 BMJ Publishing Group and British Cardiac Society. All angina/non-ST segment elevation myocardial rights reserved; no part of this publication may be reproduced, infarction treated very early and predominantly with stored in a retrieval system, or transmitted in any form or by percutaneous coronary intervention C Mueller, any means, electronic, mechanical, photocopying, recording, or otherwise without prior permission F-J Neumann, A P Perruchoud, H J Buettner Authors are required to grant Heart an exclusive licence to ...... publish; further details available online at www.heartjnl.com/ misc/ifora.shtml Congenital heart disease N Heart is published by BMJ Publishing Group, typeset by 908 Echocardiographic predictors of adverse clinical events The Charlesworth Group, and printed in UK on acid-free paper www.publicationethics.org.uk by Unwin Brothers, Woking in children with dilated cardiomyopathy: a prospective N Periodicals postage paid, Rahway, NJ. Postmaster: send This journal is a member of and clinical study C J McMahon, S F Nagueh, R S Eapen, address changes to: Heart, c/o Mercury Airfreight subscribes to the principles of the W J Dreyer, I Finkelshtyn, X Cao, B W Eidem, L I Bezold, International Ltd, 365 Blair Road, Avenel, NJ 07001, USA Committee on Publication Ethics S W Denfield, J A Towbin, R H Pignatelli contents HEART Volume 90 Number 8 August 2004

916 Poor sensitivity of routine fetal anomaly ...... ultrasound screening for antenatal detection of Electronic pages atrioventricular septal defect H ter Heide, J D R Thomson, G A Wharton, J L Gibbs e45 Late incomplete lesion coverage following Cypher stent deployment for diffuse right coronary artery 918 Persistent pulmonary hypertension late after stenosis A Halkin, S Carlier, M B Leon Heart: first published as on 1 August 2004. Downloaded from neonatal aortic valvotomy: a consequence of an e46 Treatment of an ostial and a bifurcation lesion expanded surgical cohort M Burch, L Kaufman, with a new directional atherectomy device N Archer, I Sullivan L Favero, J B Simpson, B Reimers 921 Clinical impact of first and early second trimester e47 Constrictive pericarditis and pleuropulmonary fetal echocardiography on high risk pregnancies fibrosis secondary to cabergoline treatment for J S Carvalho, G Moscoso, A Tekay, S Campbell, Parkinson’s disease M Townsend, D H MacIver B Thilaganathan, E A Shinebourne e48 Extensive primary cardiac liposarcoma with multiple functional complications S Uemura, ...... M Watanabe, H Iwama, Y Saito Basic research e49 Left ventricular haemangioma with papillary 927 Dynamic changes of gene expression profiles endothelial hyperplasia and liver involvement during postnatal development of the heart in C-D Kan, C-T Yae, Y-J Yang mice H-W Chen, S-L Yu, W-J Chen, P-C Yang, ...... C-T Chien, H-Y Chou, H-N Li, K Peck, C-H Huang, F-Y Lin, J J W Chen, Y-T Lee Miscellanea 832 Electronic pages ...... 834 Images in cardiology: Complete regression of pulmonary vein aneurysm caused by mitral Scientific letters regurgitation J Beckert, N Jander 935 Central a2 adrenoceptors and the pathogenesis 846 Images in cardiology: Calcified mediastinal of carotid sinus hypersensitivity S W Parry, haematoma: a rare case of cardiac constriction M Baptist, J J Gilroy, N Steen, R A Kenny S J Leslie, E Brackenbury, J C Spratt 937 Is there a sex bias in implantable cardioverter- 852 Images in cardiology: Impending septal rupture defibrillator referral and prescription? in myocardial infarction detected by cardiac A D Staniforth, S C Sporton, N M Robinson, magnetic resonance imaging O K Mohrs, J Cooper, M J Earley, A W Nathan, R J Schilling B Nowak, T Voigtlaender

939 Heterozygosity for the haemochromatosis 858 Images in cardiology: Unstable angina in a http://heart.bmj.com/ mutation HFE C282Y is not a risk factor patient with single coronary artery I Porto, for angina G P Feeney, P A L Ashfield-Watt, A P Banning M L Burr, F D J Dunstan, I F W McDowell, 865 Images in cardiology: Septic emboli from aortic M Worwood valve endocarditis B Skaria, P Kalra, I A Simpson 941 Metoprolol prophylaxis against postoperative 870 Electronic pages atrial fibrillation increases length of hospital stay 881 Images in cardiology: Cardiac tumour in a in patients not on pre-operative b blockers: the neonate with left ventricular outflow tract b blocker length of stay (BLOS) trial E Crystal, obstruction P Manikoth, R Leanage, J Valliattu, K E Thorpe, S J Connolly, A Lamy, I Cybulsky, S M A Khusaiby on October 1, 2021 by guest. Protected copyright. S Carroll, R Roberts, M Gent 886 Images in cardiology: Electrocardiographic 943 Time course of transcardiac interleukin-6 release gated multislice computed tomography of Uhl’s after coronary stenting for stable angina anomaly N Ceviz, M Kantarci, A Okur J M Kefer, L M Galanti, C E Hanet 901 Images in cardiology: Sinus venosus type of 945 Coronary collateral flow and peripheral blood atrial septal defect with partial anomalous monocyte concentration in patients treated with pulmonary venous return evaluated by multislice granulocyte–macrophage colony stimulating CT M Otsuka, A Itoh, K Haze factor R Zbinden, R Vogel, B Meier, C Seiler 907 Images in cardiology: Free floating thrombus in left atrium P Vaid 947 Reliable detection of early myocardial dysfunction by tissue Doppler echocardiography 915 Images in cardiology: Saccular dilatations in Becker muscular dystrophy C Meune, originating from the conus artery M Yazici, O Pascal, H M Be´cane, F He´loire, D Christoforou, S Demircan, E Yasar P Laforet, B Eymard, P Gueret, F Leturcq, 926 Images in cardiology: Optimal management of D Recan, J Y Devaux, S Weber, D Duboc left ventricular aneurysms after ventricular septal defect closure V L Vida, P Marchesi, G Stellin ...... 934 Images in cardiology: Emergency balloon mitral valvotomy for severe mitral stenosis during Education in Heart pregnancy C C Shirodaria, A R J Mitchell, 949 Management of dyslipidaemia G R Thompson A P Banning 956 Interpretation of observational studies P Jepsen, 938 Web Top 10 S P Johnsen, M W Gillman, H T Sørensen 940 Images in cardiology: Saccular aneurysm on the 961 Renal dysfunction and acceleration of coronary ascending aorta after cardiac surgery disease M W Yerkey, S J Kernis, B A Franklin, S Di Stefano, J R Echevarrı´a, E Casquero K R Sandberg, P A McCullough 944 Images in cardiology: Aneurysms of coronary artery with thrombus S S Deshpande, ...... V Viswanathan, N O Bansal 946 Images in cardiology: Left main coronary artery JournalScan occlusion in a patient with solitary coronary 967 Cardiovascular highlights from non-cardiology ostium in the right aortic sinus B Ibanez, journals M Cordoba, J Farre