CCL6 Recombinant Protein Cat. No.: 96-084

CCL6 Recombinant Protein

Specifications

SPECIES: Mouse

SOURCE SPECIES: HEK293 cells

SEQUENCE: Gly 22 - Ala 116

FUSION TAG: His Tag

TESTED APPLICATIONS: WB

APPLICATIONS: This recombinant protein can be used for WB. For research use only.

PREDICTED MOLECULAR 11.4 kDa WEIGHT:

Properties

PURITY: >95% as determined by SDS-PAGE.

PHYSICAL STATE: Lyophilized

BUFFER: PBS, pH7.4

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon STORAGE CONDITIONS: reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

October 1, 2021 1 https://www.prosci-inc.com/ccl6-recombinant-protein-96-084.html Additional Info

OFFICIAL SYMBOL: Ccl6

ALTERNATE NAMES: CCL6, SCYA6, C10, MRP-1

ACCESSION NO.: P27784

GENE ID: 20305

Background and References

Chemokine (C-C motif) ligand 6 (CCL6), a member of the CC family, was initially identified as a transcript that is induced in cells upon stimulation with GMCSF. CCL6 has only been identified in rodents, A human homologue for mouse CCL6 has not been identified. The mCCL6 cDNA encodes a 116 amino acid residue precursor protein with a hydrophobic signal peptide that is cleaved to yield a 95 BACKGROUND: amino acid residue mature protein. In mice, CCL6 is expressed in cells from and lineages, where it is strongly induced upon GMCSF (Cat. # GMF-H4214) stimulation. Mouse CCL6 expression was also shown to be strongly induced by IL-4 (Cat. # IL4-H4218) in mouse and by IL13 (Cat. # IL3-H4210) in mouse lung. Mouse CCL6 is located on . The cell surface receptor for CCL6 is believed to be the CCR1.

REFERENCES: 1) Orlofsky, et al., 1991, Cell Regul. 2 (5), 403-412.

2) Ma., et al., 2004, J Immunol.172(3):1872-81.

3) Berger., et al., 1993, DNA Cell Biol. 12 (9), 839-847.

4) Kanno M, et al., 2005, J Neuroimmunol. 167(1-2): 72-80.

ANTIBODIES FOR RESEARCH USE ONLY.

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