Technical Committee on Biomedical and (TC-BHI)

MID-YEAR REPORT 2019 Prepared by: Andrew Laine (Chair) May D Wang (Vice Chair)

July 23, 2019 Outline

1. Current Membership & Keywords 2. Portfolio of Focus Initiatives 3. Website & Members @ Large (MAL) & Mailing lists 4. New initiatives / Strategic Planning BHI Opportunities and Challenges Technical Committee

Imaging Data

Disease Understanding

Omics Data

Transforming Health Care with AI and Big Data Analytics Precision, Predictive and Preventive Clincal, mHealth, sensor Data

Drug Discovery and Development Current Membership & Keywords

• Number of Members = (31 in past year) . [ADCOM/EXCOM]: Current members: . Full: 17 . May D Wang, VP Finance . Associate (first year):14 . Konstantina Nikita, AdCom Member . Affiliate (emeritus): 3 . [TA]: . By categories: . Current EMBS Distinguished Lecturers: . Georgia Tourassi, Oak Ridge National Lab, USA . Men (20) versus women (11) . EMBS Award Recipient this year: . Academia (27) versus industry and . [PUBS]: roles in EMBS (owned or co-sponsored) government (3) versus medicine (1) journals: . North&South America region (22) versus . Dimitris Fotiadis, JBHI EiC, May D Wang, JBHI Senior Europe (7) versus Asia (2) Editor, Jessilyn Dunn, Managing Editor . JBHI Associate Editors: Wei Chen, Yufei Huang, . Connections with: Omer Inan, Jie Liang, Benny Lo, Konstantina S. . Other IEEE Societies: Nikita, Constantinos Pattichis, Julien Penders, . IEEE Communication Society Edward Sazonov, . Other societies: . Yuanting Zhang, RBME EiC . America Medical Informatics Association . RBME AEs: Andrew Laine, May D Wang . HIMSS, The Society, ACM . [CONF]: . BHI2019. See later slides EMBS BHI Technical Focuses Fundamental Theoretic Informatics: Advanced Big Data Analytics, AI, and Modeling Methodologies Sensor Informatics: Wearable and Implantable Sensors Data Analytics for Personalized Smart and Connected Health Bioinformatics: Low Cost Highly Reproducible and Reliable Biomarkers for Precision Medicine Imaging Informatics: Real-Time Imaging and Integration for Improved Evidence-Based Health Care Clinical Informatics: Multi-Modality and Multi-Scale Data Analytics for Improved Decision Support! Public Health Informatics: Population-Based Integration of All Above and Social Media for Behavioral Change BHI-TC Members (2019) • Andrew Laine, Columbia U, USA • David Clifton, U. of Oxford, UK • May D Wang, Georgia Tech and Emory U, USA • Wei Chen, Fudan U, China • Metin Akay, U of Houston, USA • Parisa Rashidi, U of Florida, USA • Jie Liang, U of Illinois at Chicago, USA • Dimitrios I. Fotiadis, U of Ioannina, • Edward Sazonov, U of Alabama, USA • Steve Wong, Cornell U, Methodist Research Institute, USA • Adam Hoover, Clemson U, USA • Paolo Bonato, Harvard U, USA • Esteban Pino, U de Concepcion, Chile • Carolyn McGregor, Ontario Inst. Of Tech, Canada • Omer Inan, Georgia Tech, USA • Konstantina Nikita, National Tech U of Athens, Greece • Maria Teresa Arrendondo, U Politécnica Madrid, Spain • Bahram Parvin, U of Navada, USA • Constantinos Pattichis, U of Cyprus, Cyprus • Holly Jimison, Northeastern U, USA • Misha Pavel, Northeastern U, USA • Amy Wang, U of Alabama, USA • Yufei Huang, U of Texas, San Antonio, USA • Maria Fernanda Cabrera (Chiqui), U Politécnica Madrid, • Julien Penders, Bloom-life, USA Spain • Elliot Sloane, Villanova U, USA • Subhamoy Mandal, DKFZ, Germany • Guangzhong Yang, Imperial College, UK • Ahmed Metwally, Stanford U, USA • Yuan-Ting Zhang*, City U. of Hong Kong, HK • Jessilyn Dunn, Duke U, USA • Thomas Penzel, Berlin, Germany • Georgia Tourassi, Oak Ridge National Laboratory, USA • Elebeoba E May, U of Houston, NSF, USA BHI-TC Keywords Current High-Level TC Keywords Used for Both JBHI (Journal of Biomedical and Health Informatics), and BHI (International Conference on Biomedical and Health Informatics) . Bioinformatics; Imaging Informatics; Biomedical Signal Processing Informatics; Sensor Informatics; Behavioral Informatics; Big Data Analytics and Machine Learning; Clinical Informatics; Public Health Informatics; Precision Medicine Informatics; Disease Oriented Informatics.

• General and Theoretical Informatics Terms • 2. Health Informatics • 2. Health Informatics • Algorithms • Low cost health delivery, public and environmental health, • Behavioral health informatics • Artificial Intelligence epidemiology • Clinical information systems • Big Data analytics • Mobile and wearable technologies for elderly • Cloud computing for healthcare • Causality analysis and case-based reasoning • Mobile health • Computer games for healthcare • Computational molecular profiling • Outcome research • Computer-aided decision making • Computational genotyping • Patient tracking • Coordinated care informatics • Computational disease profiling • Personal health systems • Decision support methods and systems • Computational phenotyping • Personal/consumer health informatics • Disease profiling and personalized treatment • Data mining • Personalized health/precision medicine • E-communities, social networks and social media • Data intelligence • Preventive health • eHealth • Data quality control • Pervasive health • Electronic health records • Data privacy • Participatory health • Personal health records • Data standard • Quality of service, trust, security • Emerging IT for efficient/low-cost healthcare delivery • Data storage • Readmission profiling • Evaluation of health information systems • Decision support systems • Technology and services for assisted-living and elderly • Health data acquisition, transmission, management and visualization • Deep learning Big data to knowledge • Technology and services for home care • Health information system interoperability • Graph-theoretical applications • Telehealth • Health information systems • Knowledge modeling • Telemedicine • Health information systems and convergence of health • Machine learning • Virtual reality in medicine • Healthcare communication networks • Natural Language Processing • Healthcare modeling and simulation • Pattern recognition • High-performance computing for healthcare • Predictive analytics • Human factors (ergonomics) in health information systems • Security and authentication • Informatics for chronic disease management • Social media • Information technologies for healthcare delivery and management • Statistical data analysis • Information technologies for the management of patient safety and • Supervised learning method clinical outcomes • Unsupervised learning method • IOT – internet of things • Ontology • Knowledge discovery and management BHI-TC Keywords

• Bioinformatics • Sensor Informatics • Imaging Informatics • Bioinformatics for health monitoring • Behavioral informatics • 3D visualization • Bioinformatics databases • Body sensor networks • Augmented reality • Cancer genomics, Neuro genomics, Cardio genomics • Context awareness • Biomedical imaging marker extraction • Cloud-based -omic data analysis & storage • Data inference, mining, and trend analysis • Content-based image retrieval • Computational and statistical analysis of metagenomics • Implantable technologies and systems • Computational pathology • Computational modeling and simulations in biology, physiology and • Intelligent medical devices and sensors • DICOM and other standards medicine • Low power, wireless sensing methods and systems • Genomic image informatics • Computational systems biology • Multi-sensor data fusion • High throughput image analysis and visualization • Dynamic modeling of biomolecular regulatory and signaling networks • Physiological monitoring • Histopathological imaging informatics • Environmental genomcis and toxicogenomics • Portable miniaturized systems • Hyperspectral imaging analysis and informatics • Epigenetics and DNA methylation analysis • Sensor-based mHealth applications • Image analysis, processing and classification • Functions of microRNA and non-coding RNAs • Sensors and sensor systems • Image databases • Gene expression pattern recognition • Smart home technology • Image registration, segmentation, and compression • Genomics and protein array image analysis • Smart textile and clothes • Image rendering, reconstruction and enhancement • Gene regulation, annotation of genes • Wearable systems and sensors • Image-enabled electronic medical records • Genomics text data processing GWAS data analysis • Wireless sensors and systems • Imaging modalities • High throughput –omic data visualization • Microscopic imaging informatics • High throughput -omics data quality control • Public Health Informatics • Molecular imaging analytics • High throughput –omic (genomics, proteomics, metabolomics, • Epidemiological modeling • Metabolomic imaging informatics lipidomics, and metagenomics) data analytics for precision health • Epidemiology • Mass spectrometry imaging informatics • Integration of multi-modality omic data • Health Economics • Medical image databases • Model building for molecular, cellular and organ pathways and • Health risk evaluation and modeling • Medical image processing and visualization networks • Infectious disease outbreak modeling • PACS (Picture Archiving and Communication Systems) • Next generation sequencing data compression • Outcomes research • Proteomic image informatics • Pharmaco-genomics • Public health management solutions • Radiomics • Platforms/solutions for precision medicine • Non-medical data analytics in public health • Tele-imaging • Structural and comparative genomics • Teleradiology • Sequencing alignment, assembly, and analysis • Synthetic control systems in biomedical applications • Translational bioinformatics Validation Status: . Voted by Related Conf. or Pub. TC members for both EMBC, BHI, and JBHI? YES . Shared with a EMBS journal? YES, approved by Journal of Biomedical and Health Informatics Portfolio of Focus Initiatives Overview of Full Portfolio – [CONF]: Special topic conference(s): – 2019 International Conference on Biomedical and Health Informatics (May 19-22, 2019) – [CONF]: 2019 EMBS annual Conference (EMBC): – Theme 10 – Biomedical and Health Informatics – [Workshop] Summer School (June 2019) – Bogota, Colombia, Presenters, Andrew Laine, Columbia U, USA . TC Workshop in EMBC2019 (Berlin, Germany) • PRESENTER’S NAME: Andrew Laine, Columbia U, USA May Wang, Georgia Tech, USA . Special Session(s) in EMBC2019: To be collected . OTHER EVENTS (Lunch with leaders in BHI): May D Wang, Andrew Laine

. Networking with leaders in BHI2019: See Flyer Portfolio of Focus Initiatives (Chicago, May 2019) Past Event - organized in the covered period - (Special Topic Conference, Summer School) # Associate Editors / Instructors from the TC: 90% BHI 2019 - 75+% of 482 # Reviewers (at large) from the TC: 85% Participants from BHI-BSN2019 Financial Chair • Conference Co-Chairs Yufei Huang, Univ of Texas at San Antonio, USA • Jie Liang, Univ of Illinois at Chicago, USA Women’s Activities Co-Chairs • • Dimitrios I. Fotiadis, JBHI EiC, Univ of Ioannina, Greece Maria Teresa Arrendondo, Univ Politécnica Madrid, Spain • Technical Program Co-Chairs Holly Jimison, Northeastern Univ, USA • • David Clifton, Univ of Oxford, UK Amy Wang, Univ of Alabama, USA • Constantinos S. Pattichis, Univ of Cyprus, Cyprus Industrial Liaisson • • Georgia Tourassi, Oak Ridge National Laboratory, USA Julien Penders, Bloomlife, USA Special Session Co-Chairs Steering Committee • • Wei Chen, Fudan Univ, China Guang-Zhong Yang, Chair, Imperial College London, UK • • Edward Sazonov, Univ of Alabama, USA May D. Wang, EMBS VP, Georgia Tech and Emory Univ, USA • Workshop Co-Chairs Stephen Wong, External Partnership, Houston Methodist, USA • • Adam Hoover, Clemson Univ, USA Andrew Laine, BHI-TC Chair, Columbia Univ, USA • • Esteban Pino, Univ de Concepcion, Chile Benny Lo, BSN-TC Chair, Imperial College London, UK Rapid Fire Co-Chairs Student’s Activities Co-Chairs • • Misha Pavel, Northeastern Univ, USA Subhamoy Mandal, DKFZ, Germany • • Omer Inan, Georgia Tech, USA Ahmed Metwally, Stanford Univ, USA Portfolio of Focus Initiatives (STC, Chicago, May 2019) Past Event - organized in the covered period - (Special Topic Conference, Summer School)

BHI 2019 Technical Program Committee Yuan Luo, Northwestern University, USA Haider Abbas, National Univ of Sciences and Technology, Pakistan Hammad Naveed, National Univ of Computer & Emerging Sciences, Pakistan Nabil Alshurafa, Northwestern University, USA Ranadip Pal, Texas Tech University, USA Amir Amini, University of Louisville, USA Andreas Panayides, University of Cyprus, Cyprus Andrew Boyd, University of Illinois at Chicago, USA Misha Pavel, Northeastern University, USA Francesca Buffa, University of Oxford, UK Yang Shen, Texas A&M University, USA Maria Fernanda Cabrera, Tech University of Madrid, Spain Ye Sun, Michigan Technology University, USA Paulo de Carvalho, University of Coimbra, Portugal Toshiyo Tamura, Waseda University, Japan Maggie Cheng, Illinois Institute of Technology, USA Jie Tian, Institute of Automation, Chinese Academy of Science, China Yang Dai, University of Illinois at Chicago, USA Thanasis Tsanas, University of Edinburgh, UK Jessilyn Dunn, Stanford University, USA Vincent S. Tseng, National Cheng Kung University, Taiwan Bjoern Michael Eskofier, FAU, Germany Maarten de Vos, University of Oxford, UK Themis Exarchos, Unit of Med Tech & Intel Inf Syst, Greece Amy Y. Wang, University of Alabama at Birmingham, USA Guoliang Fan, Oklahoma State University, USA David Wong, University of Leeds, UK Hassan Ghasemzadeh, Washington State Univ, USA Winston Wu, Pharmaco-Kinesis Corporation, USA Daniela Giordano, University of Catania, Italy Wenyao Xu, University at Buffalo, USA Jackey Jiaqi Gong, University of Maryland, Baltimore County, USA Hui Yang, Pennsylvania State University, USA Ming - Chun Huang, Case Western Reserve University, USA Jinfeng Zhang, Florida State University, USA Omer T. Inan, Georgia Tech, USA Yefeng Zheng, Siemens Corporate Research, USA Walter Karlen, ETH Zurich, Switzerland Tingting Zhu, University of Oxford, UK Shen Li, University of Pennsylvania, USA Reyer Zwiggelaar, Aberystwyth University, UK

BHI-BSN 2019 Organization by Volunteer OC and Conference Catalysts

BHI2019: 1) Theme Matters  Branding BSN2019: 34% Acceptance Rate 2) Quality Matters  Reputation 41% Acceptance Rate 11% Oral Selection Rate 3) Team Matters Community Building 24% Oral Selection Rate

Jie Liang Dimitris Fotiadis Carmen Poon John A Rogers BHI2019 Chair BHI2019 Co-Chair, JBHI EiC, BSN2019 Chair BSN2019 Co-Chair U of Illinois at Chicago U of Ioannina Chinese U of Hong Kong Northwestern U

Constas S Pattichis Georgia Tourassi David Clifton Benny Lo Canan Dagdeviren Woon-Hong Yeo BHI2019 TPC Chair BHI2019 TPC Co-Chair BHI2019 TPC Co-Chair BSN2019 TPC Chair BSN2019 TPC Co-Chair BSN2019 TPC Co-Chair U of Cyprus ORNL Oxford U Imperial College MIT Media Lab Georgia Tech An Effective and Helpful PCO

IEEEIEEE BHIBHI && BSNBSN 20192018 Best Practices: Leadership, Quality, Focus, and Team

Andrew Laine Benny Lo Steve Wong Yufei Huang May D Wang Shankar Guangzhong Yang EMBS Past Present BSN-TC Chair BHI-TC BHI-BSN BHI-TC Past Chair Subramaniam BHI-BSN SC Chair BHI-TC Chair Imperial Past Chair Treasure EMBS VP Treasure EMBS President Imperial College Columbia U College Methodist U U. Texas SA Georgia Tech-Emory U UCSD BHI-BSN Joint Team BHI Team Lead, BSN Team Lead, Strategy and BHI-BSN Fund Raising EMBS Branding Leader, Sponsor Roadmap Roadmap Partnerships Financial Planning Community Leadership EMBS Tracked June 2014 Feb 2016 Feb 2017 Mar 2018 May 2019 Submission BHI2014 BHI2016 BHI2017 BHI-BSN2018 BHI-BSN2019 4-Pagers 220+36 (256) 263+51 (314) 322 294 + 111 388 +99 WS/SS/Tutorial Sessions 8 32 17 18 + 4 13 + 5 1-Pagers 39 63 89 97 + 34 128 +24 Special Session 1-P 48 58 28 ------Metin Akay Registrations: 279 335 296 442 481 . BHI - BSN IPC Chair Finance $6,208 (4.1%) -$78,065 (-36.4%) -$33,602 (-20.0%) $45,600.46 (20.46%) $55,000(25%) U of Houston Strategy & PR NOTE: Black Color: Bi-Annual Meeting (by EMBS EO); Navy Color: Annual Meeting (by EMBS EO); Red Color: Do NOT Meet IEEE 20% Surplus Purple: Annual Meeting (by Mary Ward-Cullen and Lukrecija Lelong @ IEEE, and Conference Catalyst Team) Thanks to Keynotes

Shankar Subramaniam Elazer R. Edelman Ketan Paranjape Arun Jayaraman James L. Madara

Susan Tousi (NAE) David C. Duffy John A. Rodgers (NAE, NAS) Joshua A. Gordon IEEE BHI - BSN 2019 Monday (May 20th, 2019) Featured Session Meeting with Funding Agencies 13:25pm-14:40pm, Main Hall AB

Dr. Wendy Nilsen Dr. Suzana Petanceska: Dr. Elebeoba E. May Dr. Jean Yuan (NIH/SRO) Smart Health at the National Institute on Opportunities at the NIH Peer Review and National Science Aging – Translational National Science Foundation The Biomedical Foundation Research Programs and in the Division of Molecular Computing and Health Infrastructure and Cellular Biosciences Informatics (BCHI) Panel Tuesday (May 21st, 2019) Featured Session

Clinical and Translational Lunch Panel 11:25am-12:40pm, Main Hall AB

Dr. Justin Starren Dr. Robert A. Barish Dr. Karl Kochendorfer Dr. James L. Madara Chief of Health and Vice Chancellor for Assistant Vice Chancellor CEO of the American Biomedical Informatics, Health Affairs, UIC for Health Affairs, UIC Medical Association Northwestern U. Wednesday (May 22nd, 2019) Featured Session Meeting with Editors in Chief 12:15pm-13:30pm, Main Hall AB

Dr. Dimitris Fotiadias Dr. Xiaochuan Pan Journal of Biomedical Dr. Stephen Wong IEEE Transactions on And Health Informatics Biomedical Engineering Computational Medical (JBHI) (TBME) Imaging and Graphics It Takes A Village – Acknowledging Sponsors Thanks to Participants

IEEE BHI - BSN 2019 Special Issue on IEEE J-BHI Integrative Sensor Networks, Informatics and Modeling for Precision and Preventative Medicine

Guest Editors Key Dates

Wei Chen (Fudan University, China) Deadline for Submission: October 1, 2019 David Clifton (University of Oxford, UK) First Reviews Due: January 1, 2020 Brian Telfer (MIT Lincoln Laboratory, USA) Revised Manuscript Due: March 1, 2020 Final Decision: April 1, 2020

https://jbhi.embs.org/IEEE BHI & BSN 2018 JBHI Impact Factor and Total Submissions

1800

1600 1530 • Journal Impact Factor: 1446 1400

• 2018: IF=4.22 1200 1053 • 1000 2017: IF=3.85 806 820 769 792 800 614 • 2016: IF=3.45 543 600 437 392 339 346 • 2015: IF=2.09 400 247 • 2014: IF=1.44 200 0 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 * For 2019 the total number of submissions has been calculated based on projection performed according to the number of papers submitted on May 14th, 2019. JBHI Review Process Statistics (May 9, 2019)

Journal Statistics Prior 12 Months Avg. days from submission to first decision 27.7 Avg. Reviewer turnaround time (days) - Original 18.8 Avg. Reviewer turnaround time (days) - Resubmission 0.0 Avg. Reviewer turnaround time (days) - Revision 14.3 Avg. Time to Assign Reviewer (days) - Original 7.9 Avg. Time to Assign Reviewer (days) - Resubmission 0.0 Avg. Time to Assign Reviewer (days) - Revision 3.8 Avg. days from submission to final decision 36.1 Number of Papers for Decisions (May 14, 2019)

1600

1400 118

1200

1000

800 1124

852 600 572 605 628 562 195 453 400 390 283 329 229 253 354 200 182 234 161 207 187 192 201 204 110 93 109 108 153 65 3 0 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 Accept Reject Under Review Accept* For 2019 the decisions per year correspond to May 14th 2019. Website & Members @ Large (MAL) & Mailing Lists

Current usage of MAL mailing list: URL: https://tc-bhi.embs.org/members/ . Need EMBS EO to provide such Mailing lists: data. • [email protected] Action List: • [email protected] . Decide Website Content Manager . Update Website Content. • Website Manager • Volunteer: To Be Decided. • Staff: Michael Markowycz • Website Content: • TO BE UPDATED BY both TC-BHI Volunteer and Staff. • Role of TC • Scientific Portfolio • Members and Committees • Resources and News Future Initiatives and Comments • Current initiatives: 1) Proposal for new EMBS co-sponsored workshops • AI/ML for BME and Healthcare (TC Member: Steve Wong and May D Wang) • Computational Modeling in New Era or AI (TC Member: Elebeoba E May) 2) Involve more industry and clinicians via • BHI-TC Liaisons (Andrew Laine, Steve Wong, Elliot Slaone, Jie Liang) • AMIA, JAMA, The Obesity Society, AMA 3) Connect students with experts via BHI-TC: • Subhamoy Mandal, DKFZ, Germany, and Ahmed Metwally, Stanford U, USA 4) Increase participation from female scientists via Women in BHI Chairs: • Holly Jimison, Northeastern U, USA • Maria Teresa Arrendondo, U Politécnica Madrid, Spain • Amy Wang, U of Alabama, USA

• Future Initiatives and Comments • Comments to EMBS AdCom and ExCom: The surplus made by hard work of BHI-TC volunteers should be provided to BHI-TC to continually enlarge the societal impact by promoting: • Quality and Reputation of BHI and JBHI • Membership for JBHI and BHI Organizing team (reviewers, AEs, sessions chairs, etc.) • New Initiatives and Budget Request To Use BHI Conference Surplus 1) Making JBHI Journals and BHI Conference 1st Tier Technical Journal and Conference in the World: Seed Budgets for BHI-TC Members to cost-share Face-to-Face meeting when acceptance rate drops to 15% or less: $8,000 2) BHI Specific Awards 1) Best Student Thesis Award: $1,000 2) Appreciation Certificates to BHI-TC Members or BHI Community Volunteers who Contribute Significantly to BHI (JBHI AE, BHI OC, Star Reviewers, BHI-TC Members etc.): $300 3) Increasing bound between Academic and Industry by Promoting BHI training on young professionals: Design Continuing Annual Student Datathon Competition, and EMBS-BHI Student Resume Database for Fund Raising: $2,700 4) Working with Clinical Societies to have CME Courses: MOOC Type of Course and CME Process. Want to join?

Click: https://app.smartsheet.com/b/form/0fb49dd775a34a35a1a385030dfa2282 Immediate Contribution: Co-localize with BSN BHI-BSN2020 Portfolio of Focus Initiatives Upcoming Event - organized in future years - (Special Topic Conference, Summer School)

[CONF]: Special topic conference(s): 2020 International Conference on Biomedical and Health Informatics [CONF]: 2020 EMBS annual Conference (EMBC): Theme 10 – Biomedical and Health Informatics [MEMBERS]: Summer School: To Be Organized.