US 201502824.83A1 (19) United States (12) Patent Application Publication (10) Pub. No.: US 2015/02824.83 A1 Sawada et al. (43) Pub. Date: Oct. 8, 2015

(54) BINARY FUNGICIDAL OR PESTICIDAL (86). PCT No.: PCT/EP2013/074.813 MIXTURE S371 (c)(1), (2) Date: May 19, 2015 (71) Applicant: BAYER CROPSCIENCE AG, Monheim (DE) (30) Foreign Application Priority Data Nov.30, 2012 (EP) ...... 121951743 (72) Inventors: Haruko Sawada, Langenfeld (DE); O O Ulrike Wachendorff-Neumann, Publication Classification Neuwied (DE); Elke Hellwege, (51) Int. Cl. Langenfeld (DE); Heiko Rieck, AOIN 43/56 (2006.01) Burscheid (DE); Stefan Herrmann, (52) U.S. Cl. Langenfeld (DE) CPC ...... A0IN 43/56 (2013.01) (57) ABSTRACT (73) Assignee: BAYER CROPSCIENCE AG, The present invention relates to novel mixtures, to processes Monheim (DE) for preparing these compounds, to compositions comprising these mixtures, and to the use thereofas biologically active (21) Appl. No.: 14/443,665 compounds, especially for control of harmful microorgan isms or pests in crop protection and in the protection of (22) PCT Fled: Nov. 27, 2013 materials and as plant growth regulators. US 2015/02824.83 A1 Oct. 8, 2015

BINARY FUNGCDAL OR PESTICIDAL 0013 The mixtures according to the present invention are MIXTURE now described in detail: 0001. The present invention relates to novel mixtures, to a 0014. The composition according to the present invention process for preparing these mixtures, to compositions com comprises prising these mixtures, and to the use thereofas biologically 0.015 (1) at least one compound of the general formula active mixtures, especially for control of harmful microor ganisms or pests in crop protection and in the protection of (I) materials and as plant growth regulators. 0002 Carboxamides of the general formula (I) R2 O (I) N s R2 O ^ H N N s y R1 ^ H N y R1 0016 wherein 0017 R representsrep a hydrogrOgen atOn Or a methyl 0003 wherein group and I0004) R' represents a hydrogenatom or a methyl group 0018 R representsrep a methyl group,oup, a d11difl luorom and ethyl group or a trifluoromethyl group; and I0005 R represents a methyl group, a difluoromethyl group or a trifluoromethyl group 0.019 (2) at least one biological control agent, in par 0006 are known as active compounds having a fungicidal ticular bacteria, fungi or yeasts, protozoa, viruses, ento effect (cf. WO 1986/02641 A. WO 1992/12970 A, JP 2010 mopathogenic nematodes botanical extracts and prod 83869, WO 2011/162397). ucts produced by microorganisms including proteins or 0007 Moreover, it is known that these compounds can be secondary metabolites. mixed with different pesticidal active ingredients; resulting 0020. Accordingly, the present invention is directed to compositions are for example known from WO 2011/135827 mixture of the compounds of the formula (I) and one biologi A WO 2011/135828 A, WO 2011/135830 A, WO 2011/ cal control agent (II), in particular bacteria, fungi or yeasts, 135831, WO 2011/135832 A, WO 2011/135833A, WO 2011/ protozoa, viruses, entomopathogenic nematodes or a mutant 135834 AWO 2011/135835 A, WO 2011/135836 A. WO of these strains having all the identifying characteristics of the 2011/135837 A., WO 2011/135838 A., WO 2011/135839 A, respective strain, botanical extracts and products produced by and WO 2011/135840 A. microorganisms including proteins or secondary metabolites 0008 Since the ecological and economic demands made that exhibit activity against phytopathogenic fungi and pests. on modern active ingredients, for example fungicides, are 0021. The compounds of the formula (I) are known from increasing constantly, for example with respect to activity prior art; preparation of the compounds thereof is described spectrum, toxicity, selectivity, application rate, formation of for example in WO 1986/02641 A, WO 1992/12970 A, JP residues and favourable manufacture, and there can also be 2010-83869, WO 2011/162397). problems, for example, with resistances, there is a constant need to develop novel fungicidal compositions which have 0022. In a preferred embodiment of the present invention, advantages over the known compositions at least in some the compound of the general formula (I) is represented by one aaS. of the compounds (I-1) to (I-6): 0009. It has now surprisingly found out that mixtures com prising at least one compound of the above-shown formula (I) and at least one biological control agent have a Superior (I-1) efficiency as those mixtures known from prior art. 0010. The mixtures according to the present invention show a Superior efficiency against harmful microorganisms or pests, in particular insects, mites, nematodes or phytopatho genic fungi as compared with the compositions known from prior art. 0011. In particular, the mixtures according to the present (I-2) invention possess preferably a synergistic effect in their appli cation against harmful microorganisms or pests, in particular insects, mites, nematodes or phytopathogenic fungi. 0012. Furthermore, the mixtures according to the present invention possess a Superior synergistic effect as compared with the known mixtures of the prior art against harmful microorganisms or pests, in particular insects, mites, nema todes or phytopathogenic fungi. US 2015/02824.83 A1 Oct. 8, 2015

-continued (0026. Formula (I-(R)) (I-3)

(I-4) 0027 or by 0028 Formula (I-(S))

/ N (I-5) O 0029 wherein in the compounds of the general formula N 7 N and (I-(R)) and (I-(S)) the specific residues have the following N meaning: 0030) R' represents a hydrogenatom or a methyl group y and (I-6) I0031) R' represents a methyl group, a difluoromethyl O group or a trifluoromethyl group. 0032. The compound of the formula (I) may be repre sented by a mixture of the compounds of the general formulae M NH (I-(S)) and (I-(R)). However, preferably the enantiomer ratio N R form/S form of the compound of the general formula (I) is N 80/20 or more, more preferably, the enantiomer ratio R form/S form of the compound of the general formula is 90/10 to 10000/1, much more preferably the enantiomer ratio R form/S form of the compound of the general formula (I) is 0023 The compound of the general formula (I) is prefer 95/5 to 10000/1, most preferably the enantiomer ratio R form/S form of the compound of the general formula (I) is ably selected form the group consisting of the compounds of 98.71 to 100071. the formula (I-1), (I-2), and (I-5). More preferably, the com 0033 Taking the preferred definitions of the substituents pound of the general formula (I) is the compound of the RandR mentioned above into consideration, the compound formula (I-1). of the general formula (I) is selected from one of the following 0024. The compound of the formula (I) mentioned as a compounds mandatory part of the mixture according to the present inven tion comprises a sterocentre as shown in the above scheme: (I-1(S)) O HFC (I) R2 O ( yM (I-1(R)) Y R1 O / HFC

0025. Accordingly, two stereoisomers are known from the (N compounds of the formula (I) which are all part of the present N invention (WO 2011/162397). Accordingly, the compound of / the formula (I) is either represented by US 2015/02824.83 A1 Oct. 8, 2015

-continued -continued

(I-2(S)) (I-5(R)) O

N N W H N - N 2 / CH. H.

0034 Preferably, the compound of the general formula (I) is selected from compound ((I-1 (S)), (I-1(R)), ((I-2(S)). (I-2 (R)), and ((I-5(S)). (I-5(R)). 0035 More preferably, the compound of the general for mula (I) is selected from compound ((I-1 (S)) or (I-1(R)). 0036. The compounds of the formula (I) are mixed with at least one biological control agent, in particular bacteria, fungi or yeasts, protozoa, viruses, entomopathogenic nematodes botanical extracts and products produced by microorganisms including proteins or secondary metabolites that exhibit activity against phytopathogenic fungi and pests. 0037 Preferably, the compounds of the formula (I) are (I-3(S)) mixed with one biological control agent, in particular bacte ria, fungi or yeasts, protozoa, viruses, entomopathogenic nematodes botanical extracts and products produced by microorganisms including proteins or secondary metabolites that exhibit activity against phytopathogenic fungi and pests. 0038 Accordingly, in the present invention the biological control agents comprise bacteria, fungi or yeasts, protozoa, viruses, entomopathogenic nematodes botanical extracts and products produced by microorganisms including proteins or secondary metabolites. 0039. Mutants of the bacterial, fungal or protozoan strains having all the identifying characteristics of the respective strain shall be included within the definition of the biological control agent, 0040. The products produced by microorganisms includ ing proteins or secondary metabolites are characterized that (I-4(S)) they exhibit activity against phytopathogenic fungi and pests. 0041 Accordingly, in the present invention biological control agents consist of bacteria, fungi or yeasts, protozoa, viruses, entomopathogenic nematodes botanical extracts and products produced by microorganisms including proteins or secondary metabolites. 0042. Accordingly, in the present invention biological control agents are in particular bacteria, fungi or yeasts, pro tozoa, viruses, entomopathogenic nematodes botanical extracts and products produced by microorganisms including proteins or secondary metabolites. 0043. Accordingly, in the present invention biological control agents include: 0044 (1) bacteria, 0045 (2) fungi or yeasts, 0046 (3) protozoas, 0047 (4) viruses, (I-5(S)) 0048 (5) entomopathogenic nematode, 0049 (6) products produced by microorganisms including proteins or secondary metabolites and 0050 (7) botanical extracts 0051 Biological control agents which are summarized under the term “bacteria' include but are not limited to spore forming, root-colonizing bacteria, or bacteria useful as bio insecticide, biofungicide or bionematicide. Examples of Such bacteria to be used or employed according to the invention US 2015/02824.83 A1 Oct. 8, 2015

include but are not limited to: (1.1) Agrobacterium radio Bacillus thuringiensis Subsp. thuringiensis (products known bacter, (1.2) Bacillus acidocaldarius, (1.3) Bacillus acidot as Bikol), (1.72) Bacillus thuringiensis var. 7216 (products errestris, (1.4) Bacillus agri, (1.5) Bacillus aizawaii, (1.6) known as Amactic, Pethian), (1.73) Bacillus thuringiensis Bacillus albolactis, (1.7) Bacillus alcalophilus, (1.8) Bacillus var. T36 (products known as Cahat), (1.74) Bacillus thuring alvei, (1.9) Bacillus aminoglucosidicus, (1.10) Bacillus ami iensis strain BD #32 (Accession No. NRRL B-21530), (1.75) novorans, (1.11) Bacillus amylolyticus (also known as Paeni Bacillus thuringiensis strain AQ52 (Accession No. NRRL bacillus amylolyticus), (1.12) Bacillus amyloliquefaciens, in B-21619), (1.76) Bacillus uniflagellatus, (1.77) Bradyrhizo particular strain IN937a, (1.13) Bacillus amyloliquefaciens, bium japonicum (products known as Soy Select), (1.78) in particular strain FZB42 (product known as RhizoVital(R), Bacillus sp. strain AQ175 (ATCC Accession No. 55608), (1.14) Bacillus amyloliquefaciens strain B3 (1.15) Bacillus (1.79). Bacillus sp. strain AQ177 (ATCC Accession No. aneurinolyticus, (1.16) Bacillus atrophaeus, (1.17) Bacillus 55609), (1.80) Bacillus sp. strain AQ178 (ATCC Accession azotoformans, (1.18) Bacillus badius, (1.19) Bacillus cereus, No. 53522), (1.81) Brevibacillus brevis, in particular strain in particular spores of Bacillus cereus strain CNCM I-1562 SS86-3, (1.82) Brevibacillus brevis, in particular strain SS86 (cf. U.S. Pat. No. 6,406,690), (1.20) Bacillus chitinosporus, 4 (1.83) Brevibacillus brevis, in particular strain SS86-5, in particular strain AQ746 (Accession No. NRRL B-21618), (1.84) Brevibacillus brevis, in particular strain 2904, (1.85) (1.21) Bacillus circulans (1.22) Bacillus coagulans, (1.23) Brevibacillus laterosporus, in particular strain 64 (1.86) Bacillus fastidiosus, (1.24) Bacillus firmus, in particular Brevibacillus laterosporus, in particular strain 1111, (1.87) strain I-1582 (products known as Bionem, VOTIVO), (1.25) Brevibacillus laterosporus, in particular strain 1645, (1.88) Bacillus kurstaki, (1.26) Bacillus lacticola, (1.27) Bacillus Brevibacillus laterosporus, in particular strain 1647 (1.89) lactimorbus, (1.28) Bacillus lactis, (1.29) Bacillus lat Chromobacterium subtsugae, in particular strain PRA A4-1T erosporus (also known as Brevibacillus laterosporus), (1.30) (products known as Gandevo), (1.90) Delftia acidovorans, in Bacillus lautus, (1.31) Bacillus lentimorbus, (1.32) Bacillus particular strain RAY209 (products known as BioBoost(R), lentus, (1.33) Bacillus licheniformis, (1.34) Bacillus maroc (1.91) Lactobacillus acidophilus (products known as Fruit canus, (1.35) Bacillus megaterium (products known as Bio san), (1.92) Lysobacter antibioticus, in particular strain 13-1 Arc), (1.36) Bacillus metiens, (1.37) Bacillus mycoides, in (cf. Biological Control 2008, 45,288-296), (1.93) Lysobacter particular strain AQ726 (Accession No. NRRL B21664), enzymogenes, in particular strain C3 (cf. J Nematol. 2006 (1.38) Bacillus mycoides isolate J (Brm.J), (1.39) Bacillus June; 38(2): 233-239), (1.94) Paenibacillus alvei, in particu natto, (1.40) Bacillus nematocida, (1.41) Bacillus nigrifi lar strains III3DT-1A (Bacillus genetic stock center, Novem cans, (l.42) Bacillus nigrum, (1.43) Bacillus pantothenticus, ber 2001), (1.95) Paenibacillus alvei, in particular strain (1.44) Bacillus popillae (products known as Cronox), (1.45) III2E (Bacillus genetic stock center, November 2001), (1.96) Bacillus psychrosaccharolyticus, (1.46) Bacillus pumilus, in Paenibacillus alvei, in particular strain 46C3 (Bacillus particular strain GB34 (products known as Yield Shield)), genetic stock center, November 2001), (1.97) Paenibacillus (1.47) Bacillus pumilus, in particular strain QST2808 (Acces alvei, in particular strain 2771 (Bacillus genetic stock center, sion No. NRRL B-30087, products known as Sonata QST November 2001), (1.98) Paenibacillus polymyxa, (1.99) 2808(R), (1.48) Bacillus pumilus, in particular strain AQ717 Paenibacillus popilliae, (1.100) Pantoea agglomerans, (Accession No. NRRL B21662), (1.49) Bacillus Siamensis, (1.101) Pasteuria penetrans (products known as Pasteuria (1.50) Bacillus Smithii, (1.51) Bacillus sphaericus (products wettable powder), (1.102) Pasteuria usgae (products known known as VectoLexs(R), (1.52) Bacillus subtilis, in particular as EconemTM) (1.103) Pectobacterium carotovorum (prod strain GB03 (products known as KodiakR), (1.53) Bacillus ucts known as BioKeeper), (1.104) Pseudomonas aeruginosa subtilis, in particular strain QST713/AQ713 (Accession No. (products known as Guiticid), (1.105) Pseudomonas aureo NRRL B-21661, products known as Serenade QST 713(R), faciens (products known as Agate-25K), (1.106) Pseudomo Serenade Soil, Serenade Max), (1.54) Bacillus subtilis, in nas cepacia, in particular strain M54, (1.107) Pseudomonas particular strain AQ743 (Accession No. NRRL B-21665), cepacia, in particular strain J82, (1.108) Pseudomonas chlo (1.55) Bacillus subtilis, in particular strain AQ 153 (ATCC roraphis, in particular strain MA 342 (products known as accession No. 55614), (1.56) Bacillus subtilis var. amy Cedomon), (1.109) Pseudomonas fluorescens (products loliquefaciens Strain FZEB24 (products known as Taegro (R), known as SudoZone), (1.110) Pseudomonas proradix (prod (1.57) Bacillus thuringiensis var. israelensis (products known ucts known as Proradix(R), (1.111) Pseudomonas putida as VectoBacR), (1.58) Bacillus thuringiensis subsp. aizawai (products known as Nematsid, (1.112) Pseudomonas resino strain ABTS-1857 (products known as XenTari(R), (1.59) vorans (products known as Solanacure), (1.113) Pseudomo Bacillus thuringiensis subsp. kurstaki strain HD-1 (products nas Syringae (products known as BioSave), (1.114) Rhodo known as Dipel(R) ES), (1.60) Bacillus thuringiensis subsp. coccus globerulus strain AQ719 (Accession No. NRRL Kurstaki strain BMP 123 (1.61) Bacillus thuringiensis subsp. B21663) (1.115) Serratia entomophila (products known as tenebrionis strain NB 176 (products known as Novodor(R) InvadeTM), (1.116) Serratia marcescens, in particular strain FC), (1.62) Bacillus thuringiensis var. aegyptii (products SRM (MTCC8708), (1.117) Serratia marcescens, in particu known as Agerin), (1.63) Bacillus thuringiensis var. collmeri lar strain R35, (1.118) Streptomyces candidus (products (products known as Tian BaoBTc), (1.64) Bacillus thuring known as BioAidTM), (1.119) Streptomyces colombiensis iensis var. darmstadiensis (products known as Baciturin, (products known as Mycoside), (1.120) Streptomyces gallbus, Kolepterin), (1.65) Bacillus thuringiensis var. dendrolimus in particular strain K61 (products known as Mycostop(R), cf. (products known as Dendrobacillin), (1.66) Bacillus thuring Crop Protection 2006, 25, 468-475), (1.121) Streptomyces iensis var. galleriae (products known as Enterobactin), (1.67) gallbus, in particular strain QST 6047, Accession No. NRRL Bacillus thuringiensis var. japonensis (products known as 30232, (1.122) Streptomyces goshikiensis (products known Buihunter), (1.68) Bacillus thuringiensis subsp. Morrisoni, as Safegro), (1.123) Streptomyces griseoviridis (products (1.69) Bacillus thuringiensis var. San diego, (1.70) Bacillus known as Mycostop(R), cf. Microbial db of Canada), (1.124) thuringiensis subsp. thuringiensis strain MPPL002, (1.71) Streptomyces lavendulae (products known as Phytolavin US 2015/02824.83 A1 Oct. 8, 2015

300), (1.125) Streptomyces lydicus, in particular strain (2.33) Nomuraea rileyi, in particular strain GU87401 (2.34) WYCD108 (products known as ActinovateSP), (1.126) Nomuraea rileyi, in particular strain SR86151, (2.35) Nomu Streptomyces lydicus, in particular strain WYEC108 (prod raea rileyi, in particular strain CG128, (2.36) Nomuraea ucts known as Actino-iron), (1.127) Streptomyces prasinus rileyi, in particular strain VA9101 (products known as (cf. "Prasinons A and B: potent insecticides from Streptomy KongoR), (2.37) Ophiostoma piliferum, in particular strain ces prasinus’ Applied Microbiology 1973 November), D97 (products known as Sylvanex), (2.38) Paecilomyces fit (1.128) Streptomyces rimosus (products known as Rhitovit), mosoreus, in particular strain apopka 97 (products known as (1.129) Streptomyces Saraceticus (products known as PreFeRal), (2.39) Paecilomyces lilacinus, in particular spores Clanda), (1.130) Streptomyces venezuelae, (1.131) Strepto of Paecilomyces lilacinus strain 251 (products known as Bio myces sp. NRRL B-301.45 (1.132) Xanthomonas campestris, Act(R), cf. Crop Protection 2008, 27, 352-361), (2.40) (1.133) Xenorhabdus luminescens, (1.134) Xenorhabdus Paecilomyces variotii, in particular strain Q-09 (products nematophila, (1.135) Bacillus subtilis, in particular strain known as Nemaquim), (2.41) Pandora delphacis, (2.42) QST30002/AO30002 (Accession No. NRRL B-50421, cf. Penicillium bilaii, in particular strain ATCC22348 (products WO 2012/087980) and (1.136) Bacillus subtilis, in particular known as JumpStartR, PB-50, Provide), (2.43) Penicillium strain QST30004/AQ30004 (Accession No. NRRL B-50455, vermiculatum (products known as Vermiculen), (2.44) Phle cf. WO 2012/087980). biopsis gigantea (products known as Rotstop), (2.45) Pichia 0052 Mutants of the bacterial, strains having all the iden anomala, in particular strain WRL-076, (2.46) Pochonia tifying characteristics of the respective strain shall be chlamydosporia, (2.47) Pseudozyma flocculosa, in particular included within the definition of the biological control agent strain PF-A22 UL (products known as Sporodex(RL), (2.48) being bacteria, Pythium oligatulrum, in particular strain DV74 (products known as Polyversum), (2.49) Sporothrix insectorum (prod 0053 Biological control agents which are summarized ucts known as Sporothrix), (2.50) Talaromyces flavus, (2.51) under the term “fungi' or “yeasts' include but are not limited Trichoderma album (products known as Bio-Zeid), (2.52) to: (2.1) Ampelomyces quisqualis, in particular strain AQ 10 Trichoderma asperellum (products known as BIO-TAMTM), (product known as AQ 10(R), (2.2) Aureobasidium pullulans, (2.53) Trichoderma asperellum in particular strain ICC 012 in particular blastospores of strain DSM 14940. (2.3) Aure (products known as Bioten(R), (2.54) Trichoderma atroviride, Obasidium pullulans, in particular blastospores of strain DSM in particular strain CNCMI-1237,(2.55) Trichoderma gamsii 14941 or mixtures thereof (product known as Blossom Pro (products known as BIO-TAMTM), (2.56) Trichoderma gam tect(R), (2.4) Aschersonia aley rodes, (2.5) Aspergillus flavus, sii, in particular mycelial fragments, conidia & chlamy in particular strain NRRL 21882 (products known as Afla dospores of strain ICC080 (products known as Bioderma), Guard(R), (2.6) Arthrobotry's superba (Corda 1839), (2.7) (2.57) Trichoderma harmatum, (2.58) Trichoderma har Beauveria bassiana, in particular strain ATCC 74040 (prod zianum, in particular Trichoderma harzianum T39 (products ucts known as Naturalis(R), (2.8) Beauveria bassiana, in par ticular strain GHA (products known as Mycotrol, Botani known as Trichodex(R), (2.59) Trichoderma koningii (prod Gard), (2.9) Beauveria brongniartii (products known as ucts known as Trikot-S Plus), (2.60) Trichodermalignorum Beaupro), (2.10) Candida oleophila, in particular strain O (products known as Mycobac), (2.61) Trichoderma (products known as Nexy(R), Aspire), (2.11) Chaetomium polysporum, in particular strain IMI 206039, (2.62) Tricho cupreum (products known as Ketocin), (2.12) Cladosporium derma virens (products known as SoilGard), (2.63) Tsukan cladosporioides, in particular strain H39, (2.13) Conidiobo turella paurometabola (products known as HeberNemR), lus obscurus, (2.14) Coniothyrium minitans, in particular (2.64) Ulocladium oudemansii (products known as Botry strain CON/M/91-8 (products known as Contans.(R), (2.15) Zen), (2.65) Verticillium albo-atrum, in particular strain Dilophosphora alopecuri (products known as Twist Fun WCS850, (2.66) Verticillium chlamydosporium (products guSR), (2.16) Entomophthora virulenta (products known as known as Varsha), (2.67) Verticillium dahliae (products Vektor), (2.17) Fusarium oxysporum, in particular strain known as Dutch Trig), and (2.68) Zoophtora radican. Fo47 (products known as Fusaclean), (2.18) Gliocladium 0054 Mutants of the fungal strains having all the identi catenulatum, in particular strain J1446 (products known as fying characteristics of the respective strain shall be included PrestopR) or Primastop), (2.19) Hirsutella thompsonii (prod within the definition of the biological control agent being a ucts known as Mycohit or ABTEC), (2.20) Lagenidium fungus or yeast, giganteum (products known as LagineXCR by AgraGuest, 0055 Biological control agents which are summarized Inc.), (2.21) Lecanicillium lecanii, in particular conidia of under the term “protozoas' include but are not limited to: strain KVO1 (products known as Mycotal(R), Vertialec(R), (3.1) Nosema locustae (products known as NoloBait), (3.2) (2.22) Metarhizium anisopliae, in particular strain F52 (prod Thelohania solenopsis and (3.3) Vairimorpha spp. Mutants of ucts known as BIO 1020 or Met52), (2.23) Metarhizium the protozoan strains having all the identifying characteristics anisopliae var. acridum (products known as Green Muscle), of the respective strain shall be included within the definition (2.24) Metarhizium flavoviride, (2.25) Metschnikovia fructi of the biological control agent being protozoans, cola, in particular the strain NRRLY-3.0752 (product known 0056 Biological control agents which are summarized as ShemerR), (2.26) Microsphaeropsis ochracea (products under the term “viruses’ include but are not limited to: (4.1) known as MicroX(R), (2.27) Mucor haemelis (product known Adoxophyes Orana (Summer fruit tortrix) granulosis virus as BioAvard), (2.28) Muscodor albus, in particular strain (GV), (product known as BIOFA-Capex.R.), (4.2) Agrotis seg QST 20799 (products known as ArabesqueTM or AndanteTM), etum (turnip moth) nuclear polyhedrosis virus (NPV), (4.3) (2.29) Muscodor albus, in particular strain 620 (Accession Anticarsia gemmatalis (Woolly pyrol moth) mNPV (products No. NRRL30547), (2.30) Muscodor roseus strain A3-5 (Ac known as Polygen), (4.4) Autographa Californica (Alfalfa cession No. NRRL 30548), (2.31) Myrothecium verrucaria, Looper) mNPV (products known as VPN80 from Agricola El in particular strain AARC-0255 (products known as DiT Sol), (4.5) Biston suppressaria (tea looper) NPV. (4.6) Bom eraTM), (2.32) Nomuraea rileyi, in particular strain SA86101, byx mori (silkworm) NPV. (4.7) Cryptophlebia leucotreta US 2015/02824.83 A1 Oct. 8, 2015

(false codling moth) GV (products known as Cryptex). (4.8) 0.058 Biological control agents which are summarized Cydia pomonella (Codling moth) granulosis virus (GV) under the term “proteins or secondary metabolites’ include (product known as Madex Plus), (4.9) Dendrolimus puncta but are not limited to: (6.1) Harpin (isolated by Erwinia tus (Masson pine moth) CPV, (4.10) Helicoverpa armigera amylovora, products known as Harp-N-TekTM, Messenger.R, NPV (product known as AgBiTech-ViVUS Max), (4.11) EmployTM, ProActTM) Helicoverpa (previously Heliothis) zea (cornearworm) NPV 0059 Biological control agents which are summarized (products known as Elcar), (4.12) Leucoma Salicis (Satin under the term “botanical extracts' includebutare not limited moth) NPV. (4.13) Lymantria dispar (gypsy moth) NPV to: (7.1) Thymol, extracted e. g. from thyme (thymus vul (products known as Gypcheck), (4.14) Neodiprion abietis garis), (7.2) Neem tree (Azadirachta indica) oil, and therein (balsam-fir sawfly) NPV (products known as Abietiv), (4.15) Azadirachtin, (7.3) Pyrethrum, an extract made from the Neodiprion lecontei (red-headed pinesawfly) NPV (products dried flower heads of different species of the genus Tanace known as Lecontvirus), (4.16) Neodiprion sertifer (Pine saw tum, and therein Pyrethrins (the active components of the fly) NPV (products known as Neocheck-S), (4.17) Orgvia extract), (7.4) extract of Cassia nigricans, (7.5) wood extract pseudotsugata (Douglas-fir tussock moth) NPV (products of Quassia amara (bitterwood), (7.6) Rotenon, an extract known as Virtuss), (4.18) Phthorimaea operculella (tobacco from the roots and stems of several tropical and Subtropical leaf miner) GV (products known as Matapol), (4.19) Pieris plant species, especially those belonging to the genera LOn rapae (small white) GV. (4.20) Plutella xylostella (diamond chocarpus and Derris, (7.7) extract of Allium sativum (gar back moth) GV (products known as Plutec), (4.21) lic), (7.8) Quillaia extract, made from the concentrated puri Spodoptera albula (gray-streaked armyworm moth) mNPV fied extract of the outer cambium layer of the Quillaja (products known as VPN 82), (4.22) Spodoptera exempta Saponaria Molina tree, (7.9) Sabadilla (true armyworm) mNPV (products known as Spodec), (4.23) (Sabadilla Schoenocaulon officinale) seeds, in particular Spodoptera exigua (Sugarbeet armyworm) mNPV (products Veratrin (extracted from the seeds), (7.10) Ryania, an extract known as Spexit from Andermatt Biocontrol), (4.24) made from the ground stems of Ryania speciosa, in particular Spodoptera frugiperda (fall armyworm) mNPV (products Ryanodine (the active component of the extract), (7.11) known as Baculovirus VPN), (4.25) Spodoptera littoralis extract of Viscum album (mistletoe), (7.12) extract of Tanace (tobacco cutworm) NPV (products known as Spodoptrin tum vulgare (tansy), (7.13) extract of Artemisia absinthium from NPP Calliope France), and (4.26) Spodoptera litura (wormwood), (7.14) extract of Urtica dioica (stinging nettle), (oriental leafworm moth) NPV (products known as Littovir). (7.15) extract of Symphytum officinale (common comfrey), 0057 Biological control agents which are summarized (7.16) extract of Tropaeulum maius (monks cress), (7.17) under the term “entomopathogenic nematodes' include but leaves and bark of Quercus (oak tree) (7.18)Yellow mustard are not limited to: (5.1) Abbreviata caucasica, (5.2) Acuaria powder, (7.19) oil of the seeds of Chenopodium anthelminti spp., (5.3) Agamermis decaudata, (5.4) Allantonema spp., cum (wormseed goosefoot), (7.20) dried leaves of Dryopteris (5.5) Amphimermis spp., (5.6) Beddingia (Deladenus) siri filix-mas (male fern), (7.21) bark of Celastrus angulatus dicola, (5.7) Bovienema spp., (5.8) Cameronia spp., (5.9) (Chinese bittersweet), (7.22) extract of Equisetum arvense Chitwoodiella ovofilamenta, (5.10) Contortvlenchus spp., (field horsetail), (7.23) Chitin (7.24) natural extracts or simu (5.11) Culicimermis spp., (5.12) Diplotriaena spp., (5.13) lated blend of Chenopodium ambrosioides (products known Empidomermis spp., (5.14) Filipievinermis leipsandra, as Requiem), (7.25) Saponins of Chenopodium quinoa (prod (5.15) Gastromermis spp., (5.16) Gongylonema spp., (5.17) ucts known as Heads Up). Gynopoecilia pseudovipara, (5.18) Heterorhabditis bacte 0060 Particularly preferred are biological control agents riophora (products known as B-Green), (5.19) Heterorhab selected from the group of bacteria consisting of (1.12) Bacil ditis baujardi, (5.20) Heterorhabditis heliothidis (products lus amyloliquefaciens, in particular strain IN937a, (1.13) known as Nematon), (5.21) Heterorhabditis indica, (5.22) Bacillus amyloliquefaciens, in particular strain FZEB42 (prod Heterorhabditis marelatus, (5.23) Heterorhabditis megidis, uct known as RhizoVital(R), (1.16) Bacillus atrophaeus, (5.24) Heterorhabditis zealandica, (5.25) Hexamermis spp., (1.19) Bacillus cereus, in particular spores of Bacillus cereus (5.26) Hydromermis spp., (5.27) Isomermis spp., (5.28) Lim strain CNCM I-1562 (cf. U.S. Pat. No. 6,406,690), (1.20) nomermis spp., (5.29) Maupasina weissi, (5.30) Mermis Bacillus chitinosporus, in particular strain AQ746 (Accession nigrescens, (5.31) Mesomermis spp., (5.32) Neomesomermis No. NRRL B-21618, (1.21) Bacillus circulans, (1.22) Bacil spp., (5.33) Neoparasity lenchus rugulosi, (5.34) Octomyo lus coagulan, (1.24) Bacillus firmus, in particular strain mermis spp., (5.35) Parasitaphelenchus spp., (5.36) Parasi I-1582 (products known as Bionem, VOTIVO), (1.37) Bacil torhabditis spp., (5.37) Parasity lenchus spp., (5.38) Perutil lus mycoides, in particular strain AQ726 (Accession No. inermis culicis, (5.39) Phasmarhabditis hennaphrodita, NRRL B21664), (1.38) Bacillus mycoides isolate J (BmJ), (5.40) Physaloptera spp., (5.41) Protrellatus spp., (5.42) (1.44) Bacillus popillae (products known as Cronox), (1.46) Pterygodermatites spp., (5.43) Romanomermis spp., (5.44) Bacillus pumilus, in particular strain GB34 (products known Seuratum cadarachense, (5.45) Sphaerulariopsis spp., (5.46) as Yield Shield), (1.47) Bacillus pumilus, in particular strain Spirura guianensis, (5.47) Steinernema carpocapsae (prod QST2808 (Accession No. NRRL B-30087, products known ucts known as Biocontrol), (5.48) Steinernema feltiae (prod as Sonata QST 2808(R), (1.48) Bacillus pumilus, in particular ucts known as Nemasys(R), (5.49) Steinernema glaseri (prod strain AQ717 (Accession No. NRRL B21662), (1.51) Bacil ucts known as Biotopia), (5.50) Steinernema kraussei lus sphaericus (products known as VectoLeXS(R), (1.52) (products known as Larvesure), (5.51) Steinernema riobrave Bacillus subtilis, in particular strain GB03 (products known (products known as BioVector), (5.52) Steinernema scap as KodiakR), (1.53) Bacillus subtilis, in particular strain terisci (products known as Nematac S), (5.53) Steinernema QST713/AQ713 (Accession No. NRRL B-21661, products scarabaei, (5.54) Steinernema scarabaei, (5.55) Strelk known as Serenade QST 713(R), Serenade Soil, Serenade ovimermis peterseni, (5.56) Subulura spp., (5.57) Sulphure Max), (1.54) Bacillus subtilis, in particular strain AQ743 tylenchus elongatus, and (5.58) Tetrameres spp. (Accession No. NRRL B-21665), (1.55) Bacillus subtilis, in US 2015/02824.83 A1 Oct. 8, 2015

particular strain AQ 153 (ATCC accession No. 55614), (1.56) Microbial db of Canada), (1.124) Streptomyces lavendulae Bacillus subtilis var. amyloliquefaciens strain FZB24 (prod (products known as Phytolavin-300), (1.125) Streptomyces ucts known as TaegroR), (1.57) Bacillus thuringiensis var. lvdicus, in particular strain WYCD108 (products known as israelensis (products known as VectoBacR), (1.58) Bacillus ActinovateSP), (1.126) Streptomyces lydicus, in particular thuringiensis subsp. aizawai strain ABTS-1857 (products strain WYEC108 (products known as Actino-iron), (1.128) known as XenTari(R), (1.59) Bacillus thuringiensis subsp. Streptomyces rimosus (products known as Rhitovit), (1.129) Kurstaki strain HD-1 (products known as Dipel(RES), (1.60) Streptomyces Saraceticus (products known as Clanda), Bacillus thuringiensis subsp. kurstaki strain BMP 123 (1.61) (1.135) Bacillus subtilis, in particular strain QST30002/ Bacillus thuringiensis subsp. tenebrionis strain NB 176 AQ30002 (Accession No. NRRL B-50421, cf. WO 2012/ (products known as Novodor RFC), (1.62) Bacillus thuring 087980) and (1.136) Bacillus subtilis, in particular strain iensis var. aegypti (products known as Agerin), (1.63) Bacil QST30004/AQ30004 (Accession No. NRRL B-50455, cf. lus thuringiensis var. Colmeri (products known as Tian WO 2012/087980). BaoBTc), (1.64) Bacillus thuringiensis var. darmstadiensis 0061 Particularly preferred are biological control agents (products known as Baciturin, Kolepterin), (1.65) Bacillus selected from the group of fungi or yeasts consisting of (2.1) thuringiensis var. dendrolimus (products known as Dendro Ampelomyces quisqualis, in particular strain AQ 10 (product bacillin), (1.66) Bacillus thuringiensis var. galleriae (prod known as AQ 10R), (2.3) Aureobasidium pullulans, in par ucts known as Enterobactin), (1.67) Bacillus thuringiensis ticular blastospores of strain DSM 14941 or mixtures thereof var. japonensis (products known as Buihunter), (1.7l) Bacil (product known as Blossom Protect(R), (2.5) Aspergillus fla lus thuringiensis Subsp. thuringiensis (products known as vus, in particular strain NRRL 21882 (products known as Bikol), (1.72) Bacillus thuringiensis var. 7216 (products Afla-Guard(R), (2.7) Beauveria bassiana, in particular strain known as Amactic, Pethian), (1.73) Bacillus thuringiensis ATCC 74040 (products known as Naturalis), (2.8) Beauveria var. T36 (products known as Cahat), (1.76) Bacillus uni bassiana, in particular strain GHA (products known as flagellatus, (1.77) Bradyrhizobium japonicum (products Mycotrol, BotaniGard), (2.9) Beauveria brongniartii (prod known as SoySelect), (1.78) Bacillus sp. strain AQ175 ucts known as Beaupro), (2.10) Candida oleophila, in par (ATCC Accession No. 55608), (1.79). Bacillus sp. strain ticular strain O (products known as Nexy(R), Aspire), (2.11) AQ177 (ATCC Accession No. 55609), (1.80) Bacillus sp. Chaetomium cupreum (products known as Ketocin), (2.14) strain AQ178 (ATCC Accession No. 53522), (1.81) Breviba Coniothyrium minitans, in particular strain CON/M/91-8 cillus brevis, in particular strain SS86-3, (1.82) Brevibacillus (products known as Contans.(R), (2.15) Dilophosphora alope brevis, in particular strain SS86-4, (1.83) Brevibacillus curi (products known as Twist Fungus(R), (2.16) Entomoph brevis, in particular strain SS86-5, (1.84) Brevibacillus thora virulenta (products known as Vektor), (2.17) Fusarium brevis, in particular strain 2904, (1.85) Brevibacillus lat Oxysporum, in particular strain Fo47 (products known as erosporus, in particular strain 64, (1.86) Brevibacillus lat Fusaclean), (2.18) Gliocladium catenulatum, in particular erosporus, in particular strain 1111, (1.87) Brevibacillus lat strain J1446 (products known as PrestopR) or Primastop), erosporus, in particular strain 1645, (1.88) Brevibacillus (2.19) Hirsutella thompsonii (products known as Mycohit or laterosporus, in particular strain 1647 (1.89) Chromobacte ABTEC), (2.20) Lagenidium giganteum (products known as rium subtsugae, in particular strain PRAA4-1T (products LagineXOR by AgraGuest, Inc.), (2.21) Lecanicillium lecanii, known as Gandevo), (1.90) Delftia acidovorans, in particular in particular conidia of strain KVO1 (products known as strain RAY209 (products known as BioBoost(R), (1.91) Lac Mycotal(R), Vertialec(R), (2.22) Metarhizium anisopliae, in tobacillus acidophilus (products known as Fruitsan), (1.92) particular strain F52 (products known as BIO 1020 or Lysobacter antibioticus, in particular strain 13-1 (cf. Biologi Met52), (2.23) Metarhizium anisopliae var. acridum (prod cal Control 2008, 45,288-296), (1.101) Pasteuria penetrans ucts known as Green Muscle), (2.25) Metschnikovia fructi (products known as Pasteuria wettable powder), (1.102) Pas cola, in particular the strain NRRLY-3.0752 (product known teuria usgae (products known as EconemTM), (1.103) Pecto as ShemerR), (2.26) Microsphaeropsis ochracea (products bacterium carotovorum (products known as Biokeeper), known as) MicroX(R), (2.27) Mucor haemelis (product known (1.104) Pseudomonas aeruginosa (products known as Guiti as BioAvard), (2.28) Muscodor albus, in particular strain cid), (1.105) Pseudomonas aureofaciens (products known as QST 20799 (products known as ArabesqueTM or AndanteTM), Agate-25K), (1.108) Pseudomonas chlororaphis, in particu (2.29) Muscodor albus, in particular strain 620 (Accession lar strain MA 342 (products known as Cedomon), (1.109) No. NRRL30547), (2.30) Muscodor roseus strain A3-5 (Ac Pseudomonas fluorescens (products known as SudoZone), cession No. NRRL 30548), (2.31) Myrothecium verrucaria, (1.110) Pseudomonas proradix (products known as Prora in particular strain AARC-0255 (products known as DiT dix), (1.111) Pseudomonas putida (products known as Nem eraTM), (2.32) Nomuraea rileyi, in particular strain SA86101, atsid, (1.112) Pseudomonas resinovorans (products known as (2.33) Nomuraea rileyi, in particular strain GU87401 (2.34) Solanacure), (1.113) Pseudomonas Syringae (products Nomuraea rileyi, in particular strain SR86151, (2.35) Nomu known as BioSave), (1.114) Rhodococcus globerulus strain raea rileyi, in particular strain CG128, (2.36) Nomuraea AQ719 (Accession No. NRRL B21663), (1.115) Serratia rileyi, in particular strain VA9101 (products known as entomophila (products known as InvadeTM), (1.118) Strepto KongoR), (2.37) Ophiostoma piliferum, in particular strain myces candidus (products known as BioAidTM), (1.119) D97 (products known as Sylvanex), (2.38) Paecilomyces Streptomyces Colombiensis (products known as Mycoside), filmosoreus, in particular strain apopka 97 (products known (1.120) Streptomyces gallbus, in particular strain K61 (prod as PreFeRal), (2.39) Paecilomyces lilacinus, in particular ucts known as Mycostop R, cf. Crop Protection 2006, 25, spores of Paecilomyces lilacinus strain 251 (products known 468-475), (1.121) Streptomyces galbus, in particular strain as BioAct(R), cf. Crop Protection 2008, 27, 352-361), (2.40) QST 6047, Accession No. NRRL 30232, (1.122) Streptomy Paecilomyces variotii, in particular strain Q-09 (products ces goshikiensis (products known as Safegro), (1.123) Strep known as Nemacquim), (2.42) Penicillium bilaii, in particular tomyces griseoviridis (products known as Mycostop(R), cf. strain ATCC22348 (products known as JumpStart(R), PB-50, US 2015/02824.83 A1 Oct. 8, 2015

Provide), (2.43) Penicillium vermiculatum (products known consisting of (5.18) Heterorhabditis bacteriophora (products as Vermiculen), (2.44) Phlebiopsis gigantea (products known known as B-Green), (5.20) Heterorhabditis heliothidis (prod as Rotstop), (2.47) Pseudozyma flocculosa, in particular ucts known as Nematon), (5.47) Steinernema carpocapsae strain PF-A22 UL (products known as Sporodex(RL), (2.48) (products known as Biocontrol), (5.48) Steinernema feltiae Pythium oligandrum, in particular strain DV74 (products (products known as Nemasys(R), (5.49) Steinernema glaseri known as Polyversum), (2.49) Sporothrix insectorum (prod (products known as Biotopia), (4.50) Steinernema kraussei ucts known as Sporothrix), (2.51) Trichoderma album (prod (products known as Larvesure), (5.51) Steinernema riobrave ucts known as Bio-Zeid), (2.52) Trichoderma asperellum (products known as BioVector), and (5.52) Steinernema scap (products known as BIO-TAMTM), (2.53) Trichoderma terisci (products known as Nematac S). asperellum in particular strain ICC 012 (products known as 0065 Particularly preferred are biological control agents Bioten(R), (2.54) Trichoderma atroviride, in particular strain selected from the group of proteins and secondary metabo CNCMI-1237, (2.55) Trichoderma gamsii (products known lites consisting of (6.1) Harpin (isolated by Erwinia amylo as BIO-TAMTM), (2.56) Trichoderma gamsii, in particular vora, products known as Harp-N-TekTM, Messenger.R, mycelial fragments, conidia & chlamydospores of Strain EmployTM, ProActTM) ICC080 (products known as Bioderma), (2.58) Trichoderma 0.066 Particularly preferred are biological control agents harzianum, in particular Trichoderma harzianum T39 (prod selected from the group of botanical extracts consisting of ucts known as Trichodex(R), (2.59) Trichoderma koningii (7.24) natural extracts or simulated blend of Chenopodium (products known as Trikot-S Plus), (2.60) Trichoderma ambrosioides (products known as Requiem), (7.25) Saponins lignorum (products known as Mycobac), (2.62) Trichoderma of Chenopodium quinoa (products known as Heads Up). virens (products known as SoilGard), (2.63) Tsukamurella paurometabola (products known as HeberNemR), (2.64) 0067 More particularly preferred are biological control Ulocladium oudemansi (products known as Botry-Zen), agents selected from the group of bacteria consisting of (1.12) (2.66) Verticillium chlamydosporium (products known as Bacillus amyloliquefaciens, in particular strain IN937a, Varsha) and (2.67) Verticillium dahliae (products known as (1.13) Bacillus amyloliquefaciens, in particular strain FZB42 Dutch Trig). (product known as RhizoVital(R), (1.16) Bacillus atrophaeus, (1.19) Bacillus cereus, in particular spores of Bacillus cereus 0062 Particularly preferred are biological control agents strain CNCM I-1562 (cf. U.S. Pat. No. 6,406,690), (1.20) selected from the group of protoZoas consisting of (3.1) Bacillus chitinosporus, in particular strain AQ746 (Accession Nosema locustae (products known as NoloBait). No. NRRL B-21618), (1.21) Bacillus circulans, (1.22) Bacil 0063 Particularly preferred are biological control agents lus coagulans, (1.24) Bacillus firmus, in particular strain selected from the group of viruses consisting of (4.1) Adoxo I-1582 (products known as Bionem, VOTIVO), (1.37) Bacil phyes Orana (Summer fruit tortrix) granulosis virus (GV), lus mycoides, in particular strain AQ726 (Accession No. (product known as BIOFA-Capex.R.), (4.3) Anticarsia gem NRRL B21664), (1.38) Bacillus mycoides isolate J (BmJ), matalis (Woolly pyrol moth) mNPV (products known as (1.44) Bacillus popillae (products known as Cronox), (1.46) Polygen), (4.4) Autographa Californica (Alfalfa Looper) Bacillus pumilus, in particular strain GB34 (products known mNPV (products known as VPN80 from Agricola El Sol), as Yield Shield), (1.47) Bacillus pumilus, in particular strain (4.7) Cryptophlebia leucotreta (false codling moth) GV QST2808 (Accession No. NRRL B-30087, products known (products known as Cryptex). (4.8) Cydia pomonella (Co as Sonata QST 2808(R), (1.48) Bacillus pumilus, in particular dling moth) granulosis virus (GV) (product known as Madex strain AQ717 (Accession No. NRRL B21662), (1.51) Bacil Plus), (4.10) Helicoverpa armigera NPV (product known as lus sphaericus (products known as VectoLeXS(R), (1.52) AgBiTech-ViVUS Max). (4.11) Helicoverpa (previously Bacillus subtilis, in particular strain GB03 (products known Heliothis) zea (corn earworm) NPV (products known as as KodiakR), (1.53) Bacillus subtilis, in particular strain Elcar), (4.13) Lymantria dispar (gypsy moth) NPV (products QST713/AQ713 (Accession No. NRRL B-21661, products known as Gypcheck), (4.14) Neodiprion abietis (balsam-fir known as Serenade QST 713(R), Serenade Soil, Serenade sawfly) NPV (products known as Abietiv), (4.15) Neodiprion Max), (1.54) Bacillus subtilis, in particular strain AQ743 lecontei (red-headed pinesawfly) NPV (products known as (Accession No. NRRL B-21665), (1.55) Bacillus subtilis, in Lecontvirus), (4.16) Neodiprion sertifer (Pine sawfly) NPV particular strain AQ 153 (ATCC accession No. 55614), (1.56) (products known as Neocheck-S), (4.17) Orgvia pseudot Bacillus subtilis var. amyloliquefaciens strain FZB24 (prod sugata (Douglas-fir tussock moth) NPV (products known as ucts known as) TaegroR), (1.57) Bacillus thuringiensis var. Virtuss), (4.18) Phthorimaea operculella (tobacco leaf israelensis (products known as VectoBacR), (1.58) Bacillus miner) GV (products known as Matapol), (4.20) Plutella thuringiensis subsp. aizawai strain ABTS-1857 (products xylostella (diamondback moth) GV (products known as known as XenTari(R) (1.59) Bacillus thuringiensis subsp. Plutec), (4.21) Spodoptera albula (gray-Streaked armyworm Kurstaki strain HD-1 (products known as Dipel(RES), (1.60) moth) mNPV (products known as VPN 82), (4.22) Bacillus thuringiensis subsp. kurstaki strain BMP 123 (1.61) Spodoptera exempta (true armyworm) mNPV (products Bacillus thuringiensis subsp. tenebrionis strain NB 176 known as Spodec), (4.23) Spodoptera exigua (Sugarbeet (products known as Novodor R FC), (1.62) Bacillus thuring armyworm) mNPV (products known as Spexit from Ander iensis var. aegypti (products known as Agerin), (1.63) Bacil matt Biocontrol), (4.24) Spodoptera frugiperda (fall army lus thuringiensis var. collmeri (products known as Tian worm) mNPV (products known as Baculovirus VPN), (4.25) BaoBTc), (1.64) Bacillus thuringiensis var. darmstadiensis Spodoptera littoralis (tobacco cutworm) NPV (products (products known as Baciturin, Kolepterin), (1.65) Bacillus known as Spodoptrin from NPP Calliope France), and (4.26) thuringiensis var. dendrolimus (products known as Dendro Spodoptera litura (oriental leafworm moth) NPV (products bacillin), (1.66) Bacillus thuringiensis var. galleriae (prod known as Littovir). ucts known as Enterobactin), (1.67) Bacillus thuringiensis 0064 Particularly preferred are biological control agents var. japonensis (products known as Buihunter), (1.7l) Bacil selected from the group of entomopathogenic nematodes lus thuringiensis Subsp. thuringiensis (products known as US 2015/02824.83 A1 Oct. 8, 2015

Bikol), (1.72) Bacillus thuringiensis var. 7216 (products Bacillus firmus, in particular strain I-1582 (products known known as Amactic, Pethian), (1.73) Bacillus thuringiensis as Bionem, VOTIVO), (1.47) Bacillus pumilus, in particular var. T36 (products known as Cahat), (1.78) Bacillus sp. strain strain QST2808 (Accession No. NRRL B-30087, products AQ175 (ATCC Accession No. 55608), (1.79). Bacillus sp. known as Sonata QST 2808(R), (1.52) Bacillus subtilis, in strain AQ177 (ATCC Accession No. 55609), (1.80) Bacillus particular strain GB03 (products known as Kodiak.R.), (1.53) sp. strain AQ178 (ATCC Accession No. 53522), (1.81) Brevi Bacillus subtilis, in particular strain QST713/AQ713 (Acces bacillus brevis, in particular strain SS86-3, (1.82) Brevibacil sion No. NRRL B-21661, products known as Serenade QST lus brevis, in particular strain SS86-4, (1.83) Brevibacillus 713(R), Serenade Soil, Serenade Max), (1.121) Streptomyces brevis, in particular strain SS86-5, (1.84) Brevibacillus gallbus, in particular strain QST 6047, Accession No. NRRL brevis, in particular strain 2904, (1.85) Brevibacillus lat 30232, (1.135) Bacillus subtilis, in particular strain erosporus, in particular strain 64, (1.86) Brevibacillus lat QST30002/AO30002 (Accession No. NRRL B-50421, cf. erosporus, in particular strain 1111, (1.87) Brevibacillus lat WO 2012/087980) and (1.136) Bacillus subtilis, in particular erosporus, in particular strain 1645, (1.88) Brevibacillus strain QST30004/AQ30004 (Accession No. NRRL B-50455, laterosporus, in particular strain 1647, (1.89) Chromobacte cf. WO 2012/087980). rium subtsugae, in particular strain PRAA4-1T (products 0071 Most particularly preferred are biological control known as Gandevo), (1.90) Delftia acidovorans, in particular agents selected from the group of fungi or yeasts consisting of strain RAY209 (products known as BioBoost(R), (1.91) Lac (2.20) Lagenidium giganteum (products known as LagineXOR) tobacillus acidophilus (products known as Fruitsan), (1.92) by AgraCuest, Inc.), (2.52) Trichoderma asperellum (prod Lysobacter antibioticus, in particular strain 13-1 (cf. Biologi ucts known as BIO-TAMTM) and, (2.55) Trichoderma gamsii cal Control 2008, 45,288-296), (1.103) Pectobacterium caro (products known as BIO-TAMTM). tovorum (products known as BioKeeper), (1.114) Rhodococ 0072 Most particularly preferred are biological control cus globerulus strain AQ719 (Accession No. NRRL agents selected from the group of botanical extracts consist B21663), (1.121) Streptomyces galbus, in particular strain ing of (7.24) natural extracts or simulated blend of Chenopo QST 6047, Accession No. NRRL 30232 and (1.123) Strep dium ambrosioides (products known as Requiem). tomyces griseoviridis (products known as Mycostop(R), cf. 0073. The compounds of the formula (I) and the biological Microbial db of Canada) control agent (II) as defined above of the mixture or compo 0068 More particularly preferred are biological control sition according to the present invention can be combined in agents selected from the group of fungi or yeasts consisting of any specific ratio between these two mandatory components. (2.7) Beauveria bassiana, in particular strain ATCC 74040 In the mixtures or compositions according to the invention the (products known as Naturalis(R) (2.8) Beauveria bassiana, in compounds of the general formula (I) and the biological particular strain GHA (products known as Mycotrol, Botani control agent (II) as defined above are present in a synergis Gard), (2.9) Beauveria brongniartii (products known as tically effective weight ratio of (I):(II) in a range of 1000:1 to Beaupro), (2.19) Hirsutella thompsonii (products known as 1:1000, preferably in a weight ratio of 500:1 to 1:500, most Mycohit or ABTEC), (2.20) Lagenidium giganteum (prod preferably in a weight ratio of 100:1 to 1:100. Further ratios of ucts known as LagineXOR by AgraGuest, Inc.), (2.29) Mus (I):(II) which can be used according to the present invention codor albus, in particular strain 620 (Accession No. NRRL with increasing preferences the order given are: 800:1 to 30547), (2.30) Muscodor roseus strain A3-5 (Accession No. 1:800, 700:1 to 1:700, 750:1 to 1:750, 600:1 to 1:600, 400:1 NRRL 30548), (2.31) Myrothecium verrucaria, in particular to 1:400, 300:1 to 1:300, 250:1 to 1:250, 200:1 to 1:200,95:1 strain AARC-0255 (products known as DiTeraTM), (2.42) to 1:95, 90:1 to 1:90, 85:1 to 1:85, 8.0:1 to 1:80, 75:1 to 1:75, Penicillium bilaii, in particular strain ATCC22348 (products 70:1 to 1:70, 65:1 to 1:65, 60:1 to 1:60, 55:1 to 1:55, 45:1 to known as JumpStart(R), PB-50, Provide), (2.52) Trichoderma 1:45, 40:1 to 1:40, 35:1 to 1:35, 30:1 to 1:30, 25:1 to 1:25, asperellum (products known as BIO-TAMTM), (2.53) Tricho 20:1 to 1:20, 15:1 to 1:15, 10:1 to 1:10, 5:1 to 1:5, 4:1 to 1:4, derma asperellum in particular strain ICC 012 (products 3:1 to 1:3, 2:1 to 1:2. known as) Bioten(R) (2.54) Trichoderma atroviride, in par 0074. Following combinations exemplify specific ticular strain CNCM I-1237, (2.55) Trichoderma gamsii embodiments of the mixture according to the present inven (products known as BIO-TAMTM) and (2.63) Tsukamurella tion: paurometabola (products known as HeberNemR). (0075 (I-1 (S))+(1.1), (I-1(S))+(1.2), (I-1(S))+(1.3), (I-1 0069. More particularly preferred are biological control (S))+(1.4), (I-1 (S))+(1.5), (I-1 (S))+(1.6), (I-1 (S))+(1.7), (I-1 agents selected from the group of viruses consisting of (4.3) (S))+(1.8), (I-1 (S))+(1.9). (I-1 (S))+(1.10), (I-1 (S))+(1.11), Anticarsia gemmatalis (Woolly pyrol moth) mNPV (products (I-1 (S))+(1.12), (I-1 (S))+(1.13), (I-1 (S))+(1.14), (I-1 (S))+(1. known as Polygen), (4.8) Cydia pomonella (Codling moth) 15), (I-1 (S))+(1.16). (I-1 (S))+(1.17), (I-1 (S))+(1.18), (I-1 granulosis virus (GV) (product known as Madex Plus), (4.10) (S))+(1.19). (I-1 (S))+(1.20), (I-1(S))+(1.21), (I-1 (S))+(1. Helicoverpa armigera NPV (product known as AgBiTech 22), (I-1 (S))+(1.23), (I-1 (S))+(1.24), (I-1 (S))+(1.25), (I-1 ViVUS Max). (4.11) Helicoverpa (previously Heliothis) zea (S))+(1.26), (I-1 (S))+(1.27), (I-1(S))+(1.28), (I-1 (S))+(1. (corn earworm) NPV (products known as Elcar), (4.13) 29). (I-1 (S))+(1.30), (I-1 (S))+(1.31), (I-1 (S))+(1.32), (I-1 Lymantria dispar (gypsy moth) NPV (products known as (S))+(1.33). (I-1 (S))+(1.34), (I-1(S))+(1.35), (I-1 (S))+(1. Gypcheck), (4.18) Phthorimaea operculella (tobacco leaf 36), (I-1(S))+(1.37), (I-1(S))+(1.38), (I-1(S))+(1.39), (I-1 miner) GV (products known as Matapol), (4.23) Spodoptera (S))+(1.40), (I-1 (S))+(1.41), (I-1(S))+(1.42), (I-1 (S))+(1. exigua (Sugarbeet armyworm) mNPV (products known as 43), (I-1 (S))+(1.44), (I-1 (S))+(1.45), (I-1 (S))+(1.46), (I-1 Spexit from Andermatt Biocontrol) and (4.26) Spodoptera (S))+(1.47), (I-1 (S))+(1.48), (I-1(S))+(1.49). (I-1 (S))+(1. litura (oriental leafworm moth) NPV (products known as 50), (I-1(S))+(1.51), (I-1(S))+(1.52), (I-1 (S))+(1.53), (I-1 Littovir). (S))+(1.54), (I-1 (S))+(1.55), (I-1(S))+(1.56), (I-1 (S))+(1. 0070 Most particularly preferred are biological control 57), (I-1(S))+(1.58), (I-1(S))+(1.59), (I-1 (S))+(1.60), (I-1 agents selected from the group of bacteria consisting of (1.24) (S))+(1.61). (I-1 (S))+(1.62). (I-1(S))+(1.63), (I-1 (S))+(1.

US 2015/02824.83 A1 Oct. 8, 2015 US 2015/02824.83 A1 Oct. 8, 2015 US 2015/02824.83 A1 Oct. 8, 2015 US 2015/02824.83 A1 Oct. 8, 2015 US 2015/02824.83 A1 Oct. 8, 2015 US 2015/02824.83 A1 Oct. 8, 2015

I0086 A) Fungicides I0087. The active ingredients specified herein by their “common name are known and described, for example, in the Pesticide Manual or can be searched in the internet (e.g. http://www.alanwood.net/pesticides). I0088 1) Inhibitors of the ergosterol biosynthesis, for example (1.1) aldimorph, (1.2) azaconazole, (1.3) bitertanol, (1.4) bromuconazole, (1.5) cyproconazole, (1.6) diclobutra Zole, (1.7) difenoconazole, (1.8) diniconazole, (1.9) dini conazole-M, (1.10) dodemorph, (1.11) dodemorph acetate, (1.12) epoxiconazole, (1.13) etaconazole, (1.14) fenarimol, (1.15) fenbuconazole, (1.16) fenhexamid, (1.17) fempropidin, (1.18) fempropimorph, (1.19) fluguinconazole, (1.20)

US 2015/02824.83 A1 Oct. 8, 2015 20 omyl (II-1-16), Metolcarb (II-1-17), Oxamyl (II-1-18), Pir 0115 neonicotinoids, e.g. Acetamiprid (II-4-1), imicarb (II-1-19), Propoxur (II-1-20). Thiodicarb (II-1-21), Clothianidin (II-4-2), Dinotefuran (II-4-3), Imidacloprid (II Thiofanox (II-1-22), Triazamate (II-1-23), Trimethacarb (II 4-4), Nitenpyram (II-4-5). Thiacloprid (II-4-6), and Thia 1-24), XMC (II-1-25), and Xylylcarb (II-1-26); or methoxam (II-4-7); or 0107 organophosphates, e.g. Acephate (II-1-27), AZame 0116. Nicotine (II-4-8); or thiphos (II-1-28), Azinphos-ethyl (II-1-29), Azinphos-me 0117 Sulfoxaflor (II-4-9). thyl (II-1-30), Cadusafos (II-1-31), Chlorethoxyfos (II-1-32), 0118 5) Nicotinic acetylcholine receptor (nAChR) allos Chlorfenvinphos (II-1-33), Chlormephos (II-1-34), Chlorpy teric activators, for example rifos (II-1-35), Chlorpyrifos-methyl (II-1-36), Coumaphos 0119 spinosyns, e.g. Spinetoram (II-5-1) and Spinosad (II-1-37), Cyanophos (II-1-38), Demeton-S-methyl (II-1-39), (II-5-2). Diazinon (II-1-40), Dichlorvos/DDVP (II-1-41), Dicroto I0120 6) Chloride channel activators, for example phos (II-1-42), Dimethoate (II-1-43), Dimethylvinphos (II-1- I0121 avermectins/milbemycins, e.g. Abamectin (II-6-1), 44), Disulfoton (II-1-45), EPN (II-1-46), Ethion (II-1-47), Emamectin benzoate (II-6-2), Lepimectin (II-6-3), and Mil Ethoprophos (II-1-48). Famphur (II-1-49), Fenamiphos (II bemectin (II-6-4). 1-50), Fenitrothion (II-1-51), Fenthion (II-1-52), Fosthiazate 0.122 7). Juvenile hormone mimics, for example (II-1-53), Heptenophos (II-1-54), Imicyafos (II-1-55), I0123 juvenile hormone analogues, e.g. Hydroprene (II-7- Isofenphos (II-1-56), Isopropyl O-(methoxyaminothio-phos 1), Kinoprene (II-7-2), and Methoprene (II-7-3); or phoryl) salicylate (II-1-57), Isoxathion (II-1-58), Malathion (0.124 Fenoxycarb (II-7-4); or Pyriproxyfen (II-7-5). (II-1-59), Mecarbam (II-1-60), Methamidophos (II-1-61), 0.125 8) Miscellaneous non-specific (multi-site) inhibi Methidathion (II-1-62), Mevinphos (II-1-63), Monocroto tors, for example phos (II-1-64), Naled (II-1-65), Omethoate (II-1-66), Oxy 0.126 alkylhalides, e.g. Methyl bromide (II-8-1) and other demeton-methyl (II-1-67), Parathion (II-1-68), Parathion alkyl halides; or methyl (II-1-69), Phenthoate (II-1-70), Phorate (II-1-71), (O127 Chloropicrin (II-8-2); or Sulfuryl fluoride (II-8-3); Phosalone (II-1-72), Phosmet (II-1-73), Phosphamidon (II or Borax (II-8-4); or Tartar emetic (II-8-5). 1-74), Phoxim (II-1-75), Pirimiphos-methyl (II-1-76), Pro I0128 9) Selective homopteran feeding blockers, e.g. fenofos (II-1-77), Propetamphos (II-1-78), Prothiofos (II-1- Pymetrozine (II-9-1); or Flonicamid (II-9-2). 79), Pyraclofos (II-1-80), Pyridaphenthion (II-1-81), I0129. 10) Mite growth inhibitors, e.g. Clofentezine (II-10 Quinalphos (II-1-82), Sulfotep (II-1-83), Tebupirimfos (II-1- 1), Hexythiazox (II-10-2), and Diflovidazin (II-10-3); or 84), Temephos (II-1-85), Terbufos (II-1-86), Tetrachlorvin I0130. Etoxazole (II-10-4). phos (II-1-87). Thiometon (II-1-88), Triazophos (II-1-89), I0131 12) Inhibitors of mitochondrial ATP synthase, for Trichlorfon (II-1-90), and Vamidothion (II-1-91). example Diafenthiuron (II-12-1); or 0108) 2) GABA-gated chloride channel antagonists, for 0132 organotin miticides, e.g. AZocyclotin (II-12-2), example Cyhexatin (II-12-3), and Fenbutatin oxide (II-12-4); or (0.133 Propargite (II-12-5); or Tetradifon (II-12-6). 0109 cyclodiene organochlorines, e.g. Chlordane (II-2-1) 0.134 13) Uncouplers of oxidative phoshorylation via dis and Endosulfan (II-2-2); or ruption of the proton gradient, for example Chlorfenapyr 0110 phenylpyrazoles (fiproles), e.g. Ethiprole (II-2-3) (II-13-1), DNOC (II-13-2), and Sulfluramid (II-13-3). and Fipronil (II-2-4). 0.135 14) Nicotinic acetylcholine receptor (nAChR) chan 0111. 3) Sodium channel modulators/voltage-dependent nel blockers, for example Bensultap (II-14-1), Cartap hydro Sodium channel blockers, for example chloride (II-14-2). Thiocyclam (II-14-3), and Thiosultap-so dium (II-14-4). 0112 pyrethroids, e.g. Acrinathrin (II-3-1). Allethrin (II 0.136. 15) Inhibitors of chitin biosynthesis, type 0, for 3-2), d-cis-trans Alethrin (II-3-3), d-trans Allethrin (II-3-4), example Bistrifluron (II-15-1), ChlorfluaZuron (II-15-2), Bifenthrin (II-3-5), Bioallethrin (II-3-6), Bioallethrin S-cy Diflubenzuron (II-15-3). Flucycloxuron (II-15-4), clopentenyl isomer (II-3-7), Bioresmethrin (II-3-8), Cyclo Flufenoxuron (II-15-5), Hexaflumuron (II-15-6), Lufenuron prothrin (II-3-9), Cyfluthrin (II-3-10), beta-Cyfluthrin (II-3- (II-15-7), Novaluron (II-15-8), Noviflumuron (II-15-9), 11), Cyhalothrin (II-3-12), lambda-Cyhalothrin (II-3-13), Teflubenzuron (II-15-10), and Triflumuron (II-15-11). gamma-Cyhalothrin (II-3-14), Cypermethrin (II-3-15). I0137) 16) Inhibitors of chitin biosynthesis, type 1, for alpha-Cypermethrin (II-3-16), beta-Cypermethrin (II-3-17), example Buprofezin (II-16-1). theta-Cypermethrin (II-3-18), Zeta-Cypermethrin (II-3-19), 0.138 17) Moulting disruptors, for example Cyromazine Cyphenothrin (1R)-trans isomers (II-3-20), Deltamethrin (II-17-1). (II-3-21), Empenthrin (EZ)-(1R) isomers) (II-3-22), Esfen 0.139. 18) Ecdysone receptor agonists, for example Chro Valerate (II-3-23), Etofenprox (II-3-24), Fenpropathrin (II-3- mafenozide (II-18-1), Halofenozide (II-18-2), Methoxy 25), Fenvalerate (II-3-26), Flucythrinate (II-3-27), Flu fenozide (II-18-3), and Tebufenozide (II-18-4). methrin (II-3-28), tau-Fluvalinate (II-3-29), Halfenprox (II 0140. 19) Octopamine receptor agonists, for example 3-30). Imiprothrin (II-3-31), Kadethrin (II-3-32), Permethrin Amitraz (II-19-1). (II-3-33), Phenothrin (1R)-trans isomer) (II-3-34), Pral 0.141. 20) Mitochondrial complex III electron transport lethrin (II-3-35), Pyrethrine (pyrethrum) (II-3-36), Res inhibitors, for example Hydramethylnon (II-20-1); or Ace methrin (II-3-37), Silafluofen (II-3-38), Tefluthrin (II-3-39), quinocyl (II-20-2); or Fluacrypyrim (II-20-3). Tetramethrin (II-3-40), Tetramethrin (1R) isomers) (II-3- 0142. 21) Mitochondrial complex I electron transport 41), Tralomethrin (II-3-42), and Transfluthrin (II-3-43); or inhibitors, for example 0113 DDT (II-3-44); or Methoxychlor (II-3-45). 0.143 METI acaricides, e.g. Fenazaquin (II-21-1), Fenpy 0114. 4) Nicotinic acetylcholine receptor (nAChR) ago roximate (II-21-2), Pyrimidifen (II-21-3), Pyridaben (II-21 nists, for example 4), Tebufenpyrad (II-21-5), and Tolfenpyrad (II-21-6); or

US 2015/02824.83 A1 Oct. 8, 2015 22

(known from WO2005/085216), methyl 2-[2-({3-bromo-1- 0157. The treatment of plants or plant parts can be carried (3-chloropyridin-2-yl)-1H-pyrazol-5-yl)carbonyl)amino)-5- out in two or more steps: cyano-3-methylbenzoyl-2-ethylhydrazinecarboxylate (II 0158 a) with a compound of general formula (I), and 29-69) (known from WO2005/085216), methyl 2-[2-({3- 0159 b) at least one biological control agent bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl) 0160 wherein the two components are applied separately to the crop at the same or different plant growth stages includ carbonyl)amino)-5-cyano-3-methylbenzoyl-2- ing post harvest treatment. The application of a) and b) is not methylhydrazinecarboxylate (II-29-70) (known from limited to a special order or number of applications. WO2005/085216), methyl 2-3,5-dibromo-2-({3-bromo-1- 0.161 The “composition can be prepared by formulating (3-chloropyridin-2-yl)-1H-pyrazol-5-yl)carbonyl)amino) the compounds of the formula (I) and at least one biological benzoyl-1,2-diethylhydrazinecarboxylate (II-29-71) control agent, in particular bacteria, fungi or yeasts, protozoa, (known from WO2005/085216), methyl 2-3,5-dibromo-2-({ viruses, entomopathogenic nematodes botanical extracts and 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazol-5-yl) products produced by microorganisms including proteins or carbonyl)amino)benzoyl-2-ethylhydrazinecarboxylate (II secondary metabolites as described in the above, and then 29-72) (known from WO2005/085216), (5RS,7RS.5RS, making the formulations or their diluents. 7SR)-1-(6-chloro-3-pyridylmethyl)-1,2,3,5,6,7-hexahydro 0162 For the sake of clearness, a mixture means a physi cal combination of the compounds of the formula (I) and at 7-methyl-8-nitro-5-propoxyimidazo 1,2-alpyridine (II-29 least one biological control agent as defined above, whereas a 73) (known from WO2007/101369), 2-6-2-(5- composition means a combination of the mixture together fluoropyridin-3-yl)-1,3-thiazol-5-ylpyridin-2- with further additives, such as Surfactants, solvents, carriers, ylpyrimidine (II-29-74) (known from WO2010/006713), pigments, antifoams, thickeners and extenders, in a form as 2-6-2-(pyridin-3-yl)-1,3-thiazol-5-ylpyridin-2- Suitable for agrochemical application. ylpyrimidine (II-29-75) (known from WO2010/006713), 0163 Accordingly, the present invention also relates com 1-(3-chloropyridin-2-yl)-N-4-cyano-2-methyl-6-(methyl positions for controlling harmful microorganisms, especially carbamoyl)phenyl)-3-(5-(trifluoromethyl)-1H-tetrazol-1- harmful fungi and bacteria, comprising an effective and non phytotoxic amount of the inventive mixtures. These are pref yl)methyl)-1H-pyrazole-5-carboxamide (II-29-76) (known erably fungicidal compositions which comprise agricultur from WO2010/069502), 1-(3-chloropyridin-2-yl)-N-(4-cy ally suitable auxiliaries, solvents, carriers, Surfactants or ano-2-methyl-6-(methylcarbamoyl)phenyl-3-((5-(trifluo extenders. romethyl)-2H-tetrazol-2-yl)methyl)-1H-pyrazole-5-car 0164. In the context of the present invention, “control of boxamide (II-29-77) (known from WO2010/069502), N-(2- harmful microorganisms” means a reduction in infestation by (tert-butylcarbamoyl)-4-cyano-6-methylphenyl)-1-(3- harmful microorganisms, compared with the untreated plant chloropyridin-2-yl)-3-(5-(trifluoromethyl)-1H-tetrazol-1- measured as fungicidal efficacy, preferably a reduction by yl)methyl)-1H-pyrazole-5-carboxamide (II-29-78) (known 25-50%, compared with the untreated plant (100%), more from WO2010/069502), N-(2-(tert-butylcarbamoyl)-4-cy preferably a reduction by 40-79%, compared with the ano-6-methylphenyl-1-(3-chloropyridin-2-yl)-3-((5-(trif. untreated plant (100%); even more preferably, the infection luoromethyl)-2H-tetrazol-2-yl)methyl)-1H-pyrazole-5-car by harmful microorganisms is entirely suppressed (by 70-100%). The control may be curative, i.e. for treatment of boxamide (II-29-79) (known from WO2010/069502), (1E)- already infected plants, or protective, for protection of plants N-(6-chloropyridin-3-yl)methyl-N'-cyano-N-(2,2- which have not yet been infected. difluoroethyl)ethanimidamide (II-29-80) (known from 0.165 Accordingly, the present invention also relates com WO2008/009360), N-2-(5-amino-1,3,4-thiadiazol-2-yl)-4- positions for controlling pests, especially harmful insects, chloro-6-methylphenyl-3-bromo-1-(3-chloropyridin-2-yl)- mites, arachnids and nematodes, comprising an effective and 1H-pyrazole-5-carboxamide (II-29-81) (known from non-phytotoxic amount of the inventive mixtures or compo CN102057925), methyl 2-3,5-dibromo-2-({3-bromo-1-(3- sitions. These are preferably pesticidal compositions which chloropyridin-2-yl)-1H-pyrazol-5-yl)carbonyl)amino)ben comprise agriculturally Suitable auxiliaries, Solvents, carri Zoyl-2-ethyl-1-methylhydrazinecarboxylate (II-29-82) ers, Surfactants or extenders. 0166 In the context of the present invention, “control of (known from WO2011/049233), Heptafluthrin (II-29-83), pests’ means a reduction in infestation by harmful pests, Pyriminostrobin (II-29-84), Flufenoxystrobin (II-29-85), and compared with the untreated plant measured as pesticidal 3-chloro-N'-(2-cyanopropan-2-yl)-N'-[4-(1,1,1,2,3,3,3- efficacy, preferably a reduction by 25-50%, compared with heptafluoropropan-2-yl)-2-methylphenylphthalamide (II the untreated plant (100%), more preferably a reduction by 29-86) (known from WO2012/034472). 40-79%, compared with the untreated plant (100%); even 0155 Although the mixture according to the present more preferably, the infection by pests is entirely suppressed invention may be a composition itself, the final used compo (by 70-100%). The control may be curative, i.e. for treatment sition is usually prepared by mixing the compounds of the of already infected plants, or protective, for protection of plants which have not yet been infected. formula (I) with the biological control agent as defined above 0167. The present invention also relates to a method for and an inert carrier, and if necessary, by adding a surfactant controlling pests, comprising contacting said pests or their and/or another auxiliary for formulation, Such as an extender, habitat with the above-described composition. and by formulating the mixture into oil formulation, emulsi 0168 An "effective but non-phytotoxic amount’ means an fiable concentrate, flowable formulation, wettable powder, amount of the inventive composition which is sufficient to water dispersible granules, powder, granules, or the like. The control the fungal disease of the plant in a satisfactory manner formulation, which is used alone or by adding another inert or to eradicate the fungal disease completely, and which, at component, can be used as a pesticide. the same time, does not cause any significant symptoms of 0156 Specific further components of this final composi phytotoxicity. In general, this application rate may vary tion are described later. within a relatively wide range. It depends on several factors, US 2015/02824.83 A1 Oct. 8, 2015 for example on the fungus to be controlled, the plant, the understandard pressure, for example aerosol propellants such climatic conditions and the ingredients of the inventive com as halohydrocarbons, and also butane, propane, nitrogen and positions. carbon dioxide. 0169. The present invention also relates to a method for 0179. In the formulations, it is possible to use tackifiers controlling pests, comprising contacting said pests or their Such as carboxymethylcellulose, and natural and synthetic habitat with the above-described composition. polymers in the form of powders, granules or latices, such as 0170 The present invention relates further to a method for gum arabic, polyvinyl alcohol and polyvinyl acetate, or else treating seeds, comprising contacting said seeds with the natural phospholipids, such as cephalins and lecithins, and above-described composition. synthetic phospholipids. Further additives may be mineral and vegetable oils. 0171 Finally, the present invention also relates to seed 0180. If the extender used is water, it is also possible to treated with the above-mentioned composition employ, for example, organic solvents as auxiliary Solvents. 0172 Formulations Useful liquid solvents are essentially: aromatics Such as 0173 Suitable organic solvents include all polar and non Xylene, toluene or alkylnaphthalenes, chlorinated aromatics polar organic solvents usually employed for formulation pur and chlorinated aliphatic hydrocarbons such as chloroben poses. Preferable the solvents are selected from ketones, e.g. Zenes, chloroethylenes or dichloromethane, aliphatic hydro methyl-isobutyl-ketone and cyclohexanone, amides, e.g. carbons such as cyclohexane or paraffins, for example min dimethyl formamide and alkanecarboxylic acid amides, e.g. eral oil fractions, mineral and vegetable oils, alcohols such as N,N-dimethyl decaneamide and N,N-dimethyl octanamide, butanol or glycol and their ethers and esters, ketones Such as furthermore cyclic Solvents, e.g. N-methyl-pyrrolidone, acetone, methyl ethyl ketone, methyl isobutyl ketone or N-octyl-pyrrolidone, N-dodecyl-pyrrolidone, N-octyl-capro cyclohexanone, strongly polar solvents such as dimethylfor lactame, N-dodecyl-caprolactame and butyrolactone, fur mamide and dimethyl Sulphoxide, and also water. thermore strong polar solvents, e.g. dimethylsulfoxide, and 0181. The inventive compositions may additionally com aromatic hydrocarbons, e.g. xylol, SolvessoTM, mineral oils, prise further components, for example Surfactants. Useful e.g. white spirit, petroleum, alkylbenzenes and spindle oil, Surfactants are emulsifiers and/or foam formers, dispersants also esters, e.g. propyleneglycol-monomethylether acetate, or wetting agents having ionic or nonionic properties, or adipic acid dibutylester, acetic acid hexylester, acetic acid mixtures of these surfactants. Examples of these are salts of heptylester, citric acid tri-n-butylester and phthalic acid di-n- polyacrylic acid, salts of lignoSulphonic acid, salts of phenol butylester, and also alcohols, e.g. benzyl alcohol and 1-meth sulphonic acid or naphthalenesulphonic acid, polyconden oxy-2-propanol. sates of ethylene oxide with fatty alcohols or with fatty acids 0.174. According to the invention, a carrier is a natural or or with fatty amines, substituted phenols (preferably alky synthetic, organic or inorganic Substance with which the lphenols or arylphenols), Salts of Sulphosuccinic esters, tau active ingredients are mixed or combined for better applica rine derivatives (preferably alkyl taurates), phosphoric esters bility, in particular for application to plants or plant parts or of polyethoxylated alcohols or phenols, fatty esters of poly seed. The carrier, which may be solid or liquid, is generally ols, and derivatives of the compounds containing Sulphates, inert and should be suitable for use in agriculture. Sulphonates and phosphates, for example alkylaryl polygly 0.175. Useful solid or liquid carriers include: for example col ethers, alkylsulphonates, alkylsulphates, arylsulphonates, ammonium salts and natural rock dusts, such as kaolins, protein hydrolysates, lignoSulphite waste liquors and meth clays, talc, chalk, quartz, attapulgite, montmorillonite or ylcellulose. The presence of a surfactant is necessary if one of diatomaceous earth, and synthetic rock dusts, such as finely the active ingredients and/or one of the inert carriers is divided silica, alumina and natural or synthetic silicates, res insoluble in water and when application is effected in water. ins, waxes, Solid fertilizers, water, alcohols, especially The proportion of surfactants is between 5 and 40 percent by butanol, organic solvents, mineral and vegetable oils, and weight of the inventive composition. derivatives thereof. Mixtures of such carriers can likewise be 0182 Suitable surfactants (adjuvants, emulsifiers, dis used. persants, protective colloids, wetting agent and adhesive) 0176 Suitable solid filler and carrier include inorganic include all common ionic and non-ionic Substances, for particles, e.g. carbonates, silikates, Sulphates and oxides with example ethoxylated nonylphenols, polyalkylene glycolether of linear or branched alcohols, reaction products of alkyl an average particle size of between 0.005 and 20 um, prefer phenols with ethylene oxide and/or propylene oxide, reaction ably of between 0.02 to 10 um, for example ammonium products of fatty acid amines with ethylene oxide and/or Sulphate, ammonium phosphate, urea, calcium carbonate, propylene oxide, furthermore fattic acid esters, alkyl Sul calcium Sulphate, magnesium Sulphate, magnesium oxide, fonates, alkyl Sulphates, alkyl etherSulphates, alkyl ether aluminium oxide, silicium dioxide, so-called fine-particle phosphates, arylsulphate, ethoxylated arylalkylphenols, e.g. silica, silica gels, natural or synthetic silicates, and alumosili tristyryl-phenol-ethoxylates, furthermore ethoxylated and cates and plant products like cereal flour, wood powder/saw propoxylated arylalkylphenols like Sulphated or phosphated dust and cellulose powder. arylalkylphenol-ethoxylates and -ethoxy-and-propoxylates. 0177 Useful solid carriers for granules include: for Further examples are natural and synthetic, water soluble example crushed and fractionated natural rocks such as cal polymers, e.g. lignoSulphonates, gelatine, gum arabic, phos cite, marble, pumice, Sepiolite, dolomite, and synthetic gran pholipides, starch, hydrophobic modified starch and cellulose ules of inorganic and organic meals, and also granules of derivatives, in particular cellulose ester and cellulose ether, organic material Such as sawdust, coconut shells, maize cobs further polyvinyl alcohol, polyvinyl acetate, polyvinyl pyr and tobacco stalks. rolidone, polyacrylic acid, polymethacrylic acid and co-po 0.178 Useful liquefied gaseous extenders or carriers are lymerisates of (meth)acrylic acid and (meth)acrylic acid those liquids which are gaseous at Standard temperature and esters, and further co-polymerisates of methacrylic acid and US 2015/02824.83 A1 Oct. 8, 2015 24 methacrylic acid esters which are neutralized with alkali cation forms is generally between 0.000001 to 95% by metal hydroxide and also condensation products of optionally weight, preferably between 0.0001 and 2% by weight. substituted naphthalene sulfonic acid salts with formalde 0191 The formulations mentioned can be prepared in a hyde. manner known per se, for example by mixing the active 0183 It is possible to use dyes Such as inorganic pigments, ingredients with at least one customary extender, Solvent or for example iron oxide, titanium oxide and Prussian Blue, and diluent, adjuvant, emulsifier, dispersant, and/or binder or organic dyes such as alizarin dyes, azo dyes and metal phtha fixative, wetting agent, water repellent, if appropriate desic locyanine dyes, and trace nutrients such as salts of iron, cants and UV stabilizers and, if appropriate, dyes and pig manganese, boron, copper, cobalt, molybdenum and zinc. ments, antifoams, preservatives, inorganic and organic thick 0184 Antifoams which may be present in the formula eners, adhesives, gibberellins and also further processing tions include e.g. silicone emulsions, longchain alcohols, auxiliaries and also water. Depending on the formulation type fatty acids and their salts as well as fluoroorganic Substances to be prepared further processing steps are necessary, e.g. wet and mixtures thereof. grinding, dry grinding and granulation. 0185. Examples of thickeners are polysaccharides, e.g. 0.192 The inventive mixtures or compositions may be Xanthan gum or Veegum, silicates, e.g. attapulgite, bentonite present as such or in their (commercial) formulations and in as well as fine-particle silica. the use forms prepared from these formulations as a mixture 0186 If appropriate, it is also possible for other additional with other (known) active ingredients, such as insecticides, components to be present, for example protective colloids, attractants, sterilants, bactericides, acaricides, nematicides, binders, adhesives, thickeners, thixotropic Substances, pen fungicides, growth regulators, herbicides, fertilizers, Safeners etrants, stabilizers, sequestrants, complexing agents. In gen and/or semiochemicals. eral, the active ingredients can be combined with any solid or 0193 The inventive treatment of the plants and plant parts liquid additive commonly used for formulation purposes. with the mixtures or compositions is effected directly or by 0187. The inventive mixtures or compositions can be used action on their surroundings, habitat or storage space by the as such or, depending on their particular physical and/or customary treatment methods, for example by dipping, spray chemical properties, in the form of their formulations or the ing, atomizing, irrigating, evaporating, dusting, fogging, use forms prepared therefrom, Such as aerosols, capsule Sus broadcasting, foaming, painting, spreading-on, watering pensions, cold-fogging concentrates, warm-fogging concen (drenching), drip irrigating and, in the case of propagation trates, encapsulated granules, fine granules, flowable concen material, especially in the case of seeds, also by dry seed trates for the treatment of seed, ready-to-use solutions, treatment, wet seed treatment, slurry treatment, incrustation, dustable powders, emulsifiable concentrates, oil-in-water coating with one or more coats, etc. It is also possible to emulsions, water-in-oil emulsions, macrogranules, micro deploy the mixtures or compositions by the ultra-low volume granules, oil-dispersible powders, oil-miscible flowable con method or to inject the mixtures or compositions preparation centrates, oil-miscible liquids, gas (under pressure), gas gen or the mixtures or compositions itself into the soil. erating product, foams, pastes, pesticide coated seed, (0194 Plant/Crop Protection Suspension concentrates, Suspoemulsion concentrates, soluble concentrates, Suspensions, wettable powders, soluble 0.195 The inventive mixtures or compositions have potent powders, dusts and granules, water-soluble and water-dis microbicidal activity and can be used for control of harmful persible granules or tablets, water-soluble and water-dispers microorganisms, such as phytopathogenic fungi and bacteria, ible powders for the treatment of seed, wettable powders, in crop protection and in the protection of materials. natural products and synthetic Substances impregnated with 0196. The invention also relates to a method for control active ingredient, and also microencapsulations in polymeric ling harmful microorganisms, characterized in that the inven Substances and in coating materials for seed, and also ULV tive mixtures or compositions are applied to the phytopatho cold-fogging and warm-fogging formulations. genic fungi, phytopathogenic bacteria and/or their habitat. 0188 The inventive compositions include not only formu 0.197 Fungicides can be used in crop protection for con lations which are already ready for use and can be applied trol of phytopathogenic fungi. They are characterized by an with a Suitable apparatus to the plant or the seed, but also outstanding efficacy against abroad spectrum of phytopatho commercial concentrates which have to be diluted with water genic fungi, including Soilborne pathogens, which are in par prior to use. Customary applications are for example dilution ticular members of the classes Plasmodiophoromycetes, Per in water and Subsequent spraying of the resulting spray liquor, onosporomycetes (Syn. Oomycetes), Chytridiomycetes, application after dilution in oil, direct application without Zygomycetes, Ascomycetes, Basidiomycetes and Deutero dilution, seed treatment or soil application of granules. mycetes (Syn. Fungi imperfecti). Some fungicides are sys 0189 The inventive mixtures, compositions and formula temically active and can be used in plant protection as foliar, tions generally contain between 0.05 and 99% by weight, seed dressing or soil fungicide. Furthermore, they are Suitable 0.01 and 98% by weight, preferably between 0.1 and 95% by for combating fungi, which interalia infest wood or roots of weight, more preferably between 0.5 and 90% of active ingre plant. dient, most preferably between 10 and 70% by weight. For 0198 Bactericides can be used in crop protection for con special applications, e.g. for protection of wood and derived trol of Pseudomonadaceae, Rhizobiaceae, Enterobacteri timber products the inventive mixtures, compositions and aceae, Corynebacteriaceae and Streptomycetaceae. formulations generally contain between 0.0001 and 95% by 0199 Non-limiting examples of pathogens of fungal dis weight, preferably 0.001 to 60% by weight of active ingredi eases which can be treated in accordance with the invention ent include: 0190. The contents of active ingredient in the application 0200 diseases caused by powdery mildew pathogens, for forms prepared from the formulations may vary in a broad example Blumeria species, for example Blumeria graminis, range. The concentration of the active ingredients in the appli Podosphaera species, for example Podosphaera leucotricha, US 2015/02824.83 A1 Oct. 8, 2015

Sphaerotheca species, for example Sphaerotheca fitliginea, Monographella species, for example Monographella nivalis, Uncinula species, for example Uncinula necator, Septoria species, for example Septoria nodorum, 0201 diseases caused by rust disease pathogens, for 0206 diseases caused by Smut fungi, for example Sphace example Gymnosporangium species, for example Gymno lotheca species, for example Sphacelotheca reiliana, Tilletia sporangium Sabinae, Hemileia species, for example species, for example Tilletia caries, T. controversa, Urocystis Hemileia vastatrix, Phakopsora species, for example Phako species, for example Urocystis Occulta, Ustilago species, for psora pachyrhizi and Phakopsora meibomiae, Puccinia spe example Ustilago nuda, U. nuda tritici; cies, for example Puccinia recondite, P triticina, P. graminis 0207 fruit rot caused, for example, by Aspergillus species, or P. Striiformis, Uromyces species, for example Uromyces for example Aspergillus flavus, Botrytis species, for example appendiculatus, Botrytis cinerea, Penicillium species, for example Penicil 0202 diseases caused by pathogens from the group of the lium expansium and P. purpurogenium, Sclerotinia species, for Oomycetes, for example Albugo species, for example Algubo example Sclerotinia sclerotiorum, Verticilium species, for candida, Bremia species, for example Bremia lactucae, Per example Verticilium alboatrum, onospora species, for example Peronospora pisi or P. brassi 0208 seed and soilborne decay, mould, wilt, rot and cae, Phytophthora species, for example Phytophthora damping-off diseases caused, for example, by Alternaria spe infestans, Plasmopara species, for example Plasmopara viti cies, caused for example by Alternaria brassicicola, Apha cola, Pseudoperonospora species, for example Pseudoper nomyces species, caused for example by Aphanomyces eute onospora humuli or Pseudoperonospora cubensis, Pythium iches, Ascochyta species, caused for example by Ascochyta species, for example Pythium ultimum, lentis, Aspergillus species, caused for example by Aspergillus 0203 leaf blotch diseases and leaf wilt diseases caused, flavus, Cladosporium species, caused for example by Cla for example, by Alternaria species, for example Alternaria dosporium herbarum, Cochliobolus species, caused for Solani; Cercospora species, for example Cercospora beti example by Cochliobolus sativus, (Conidiaform: Drechslera cola, Cladiosporium species, for example Cladiosporium , Bipolaris Syn: Helminthosporium); Colletotrichum species, cucumerinum, Cochliobolus species, for example caused for example by Colletotrichum coccodes, Fusarium Cochliobolus sativus (conidia form: Drechslera, Syn: Helm species, caused for example by Fusarium culmorum, Gibber inthosporium), Cochliobolus miyabeanus, Colletotrichum ella species, caused for example by Gibberella zeae, Macro species, for example Colletotrichum lindemuthanium, Cyclo phomina species, caused for example by Macrophomina conium species, for example Cycloconium oleaginum, phaseolina, Monographella species, caused for example by Diaporthe species, for example Diaporthe citri, Elsinoe spe Monographella nivalis, Penicillium species, caused for cies, for example Elsinoe fawcetti; Gloeosporium species, example by Penicillium expansium, Phoma species, caused for example Gloeosporium laeticolor, Glomerella species, for example by Phoma lingam, Phomopsis species, caused for example Glomerella Cingulata, Guignardia species, for for example by Phomopsis sojae, Phytophthora species, example Guignardia bidwelli, Leptosphaeria species, for caused for example by Phytophthora cactorum, Pyrenophora example Leptosphaeria maculans, Leptosphaeria nodorum, species, caused for example by Pyrenophora graminea, Magnaporthe species, for example Magnaporthe grisea, Pyricularia species, caused for example by Pyricularia Microdochium species, for example Microdochium nivale, Oryzae, Pythium species, caused for example by Pythium Mycosphaerella species, for example Mycosphaerella ultimum, Rhizoctonia species, caused for example by Rhizoc graminicola, M. arachidicola and M. fijiensis, tonia Solani; Rhizopus species, caused for example by Rhizo Phaeosphaeria species, for example Phaeosphaeria pus Oryzae, Sclerotium species, caused for example by Scle nodorum, Pyrenophora species, for example Pyrenophora rotium rolfsii; Septoria species, caused for example by teres, Pyrenophora tritici repentis, Ranularia species, for Septoria nodorum, Tiphula species, caused for example by example Ranularia collo-Cygni, Ranularia areola, Rhyn Tiphula incarnate, Verticillium species, caused for example chosporium species, for example Rhynchosporium secalis, by Verticillium dahliae, Septoria species, for example Septoria apii, Septoria lyco 0209 cancers, galls and witches broom caused, for persii, Tiphula species, for example Tiphula incarnate, Ven example, by Nectria species, for example Nectria galligena, turia species, for example Venturia inaequalis, 0210 wilt diseases caused, for example, by Monilinia spe 0204 root and stem diseases caused, for example, by Cor cies, for example Monilinia laxa, ticium species, for example Corticium graminearum, 0211 leafblister or leaf curl diseases caused, for example, Fusarium species, for example Fusarium oxysporum, Gaeu by Exobasidium species, for example Exobasidium vexans, mannomyces species, for example Gaeumannomyces grani 0212 Taphrina species, for example Taphrina deformans, nis, Rhizoctonia species, such as, for example Rhizoctonia 0213 decline diseases of wooden plants caused, for Solani; Sarocladium diseases caused for example by Sarocla example, by Esca disease, caused for example by Phaemo dium Oryzae, Sclerotium diseases caused for example by niella clamydospora, Phaeoacremonium aleophilum and Sclerotium Oryzae, Tapesia species, for example Tapesia acu Fomitiporia mediterranea, Eutylpa dyeback, caused for formis, Thielaviopsis species, for example Thielaviopsis example by Eutylpa lata, Ganoderma diseases caused for basicola, example by Ganoderma bominense, Rigidoporus diseases 0205 ear and panicle diseases (including corn cobs) caused for example by Rigidoporus lignosus, caused, for example, by Alternaria species, for example 0214 diseases of flowers and seeds caused, for example, Alternaria spp.; Aspergillus species, for example Aspergillus by Botrytis species, for example Botrytis cinerea, flavus, Cladosporium species, for example Cladosporium 0215 diseases of plant tubers caused, for example, by cladosporioides, Claviceps species, for example Claviceps Rhizoctonia species, for example Rhizoctonia Solani; Helm purpurea, Fusarium species, for example Fusarium cul inthosporium species, for example Helminthosporium morum, Gibberella species, for example Gibberella zeae, Solani; US 2015/02824.83 A1 Oct. 8, 2015 26

0216 Club root caused, for example, by Plasmodiophora of materials, and in the hygiene sector. They can be preferably species, for example Plamodiophora brassicae, employed as plant protection agents. They are active against 0217 diseases caused by bacterial pathogens, for example normally sensitive and resistant species and against all or Xanthomonas species, for example Xanthomonas campestris Some stages of development. The abovementioned pests pV. Oryzae, Pseudomonas species, for example Pseudomonas include: syringae pv. lachrymans, Erwinia species, for example 0224 pests from the phylum Arthropoda, especially from Erwinia amylovora. the class Arachnida, for example, Acarus spp., Aceria Shel 0218. The following diseases of soya beans can be con doni, Aculops spp., Aculus spp., Amblyomma spp., Amphitet trolled with preference: ranychus viennensis, Argas spp., Boophilus spp., Brevipalpus 0219 Fungal diseases on leaves, stems, pods and seeds spp., Bryobia graminum, Bryobia praetiosa, Centruroides caused, for example, by Alternaria leaf spot (Alternaria spec. spp., Chorioptes spp., Dermanyssus gallinae, Dermatopha atrans tenuissima), Anthracnose (Colletotrichum gloeospor goides pteronyssinus, Dermatophagoides farinae, Derma Oides dematium var. truncatum), brown spot (Septoria gly centor spp., Eotetranychus spp., Epitrimerus pyri, Eutetrany cines), cercospora leaf spot and blight (Cercospora kikuchii). chus spp., Eriophyes spp., Glycyphagus domesticus, choanephora leaf blight (Choanephora infundibulifera Halotydeus destructor; Hemitarisonemus spp., Hyalomma trispora (Syn.)), dactuliophora leaf spot (Dactuliophora gly spp., Ixodes spp., Latrodectus spp., Loxosceles spp., Metatet cines), downy mildew (Peronospora manshurica), drechslera ranychus spp., Neutrombicula autumnalis, Nuphersa spp., blight (Drechslera glycini), frogeye leaf spot (Cercospora Oligonychus spp., Ornithodorus spp., Ornithonyssus spp., soina), leptosphaerulina leaf spot (Leptosphaerulina tri Panonychus spp., Phylocoptruta oleivora, Polyphagotarson folii), phyllostica leaf spot (Phyllosticta sojaecola), pod and emus latus, Psoroptes spp., Rhipicephalus spp., Rhizoglyphus stem blight (Phomopsis sojae), powdery mildew (Mi spp., Sarcoptes spp., Scorpio maurus, Steneotarisonemus crosphaera diffusa), pyrenochaeta leaf spot (Pyrenochaeta spp., Steneotarisonemus Spinki, Tarsonemus spp., Tetrany glycines), rhizoctonia aerial, foliage, and web blight (Rhizoc chus spp., Trombicula alfreddugesi, Vaejovis spp., Vasates tonia Solani), rust (Phakopsora pachyrhizi, Phakopsora mei lycopersici; bomiae), Scab (Sphaceloma glycines), Stemphylium leaf 0225 from the class Chilopoda, for example, Geophilus blight (Stemphylium botryosum), target spot (Corynespora spp., Scutigera spp.; Cassicola). 0226 from the order or the class Collembola, for example, 0220 Fungal diseases on roots and the stem base caused, Onychiurus armatus, for example, by black root rot (Calonectria Crotalariae), 0227 from the class Diplopoda, for example, Blaniulus charcoal rot (Macrophomina phaseolina), fitsarium blight or guttulatus, wilt, root rot, and pod and collar rot (Fusarium oxysporum, 0228 from the class Insecta, e.g. from the order Blattodea, Fusarium Orthoceras, Fusarium semitectum, Fusarium equi for example, Blattella asahinai, Blattella germanica, Blatta setti), mycoleptodiscus root rot (Mycoleptodiscus terrestris), Orientalis, Leucophaea maderae, Panchlora spp., Parcob neocosmospora (Neocosmospora vasinfecta), pod and stem latta spp., Periplaneta spp., Supella longipalpa, blight (Diaporthe phaseolorum), stem canker (Diaporthe 0229 from the order Coleoptera, for example, Acalymma phaseolorum var. caulivora), phytophthora rot (Phytoph vittatum, Acanthoscelides Obtectus, Adoretus spp., Agelastica thora megasperma), brown stem rot (Phialophora gregata), alni, Agriotes spp., Alphitobius diaperinus, Amphimallonsol pythium rot (Pythium aphanidennatum, Pythium irregulare, Stitialis, Anobium punctatum, Anoplophora spp., Anthono Pythium debaryanum, Pythium myriotylum, Pythium ulti mus spp., Anthrenus spp., Apion spp., Apogonia spp., Atom mum), rhizoctonia root rot, stem decay, and damping-off aria spp., Attagenus spp., Bruchidius Obtectus, Bruchus spp., (Rhizoctonia Solani), Sclerotinia stem decay (Sclerotinia Cassida spp., Cerotoma trifurcata, Ceutorrhynchus spp., sclerotiorum), sclerotinia southern blight (Sclerotinia rolf Chaetocnema spp., Cleonus mendicus, Conoderus spp., Cos sii), thielaviopsis root rot (Thielaviopsis basicola). mopolites spp., Costelytra zealandica, Ctenicera spp., Cur 0221) The inventive fungicidal mixtures or compositions culio spp., Cryptolestes ferrugineus, Cryptorhynchus lap can be used for curative or protective/preventive control of athi, Cylindrocopturus spp., Dermestes spp., Diabrotica spp., phytopathogenic fungi. The invention therefore also relates to Dichocrocis spp., Dicladispa armigera, Diloboderus spp., curative and protective methods for controlling phytopatho Epillachna spp., Epitrix spp., Faustinus spp., Gibbium psyl genic fungi by the use of the inventive mixtures or composi loides, Gnathocerus cornutus, Hellula undalis, Heteronychus tions, which are applied to the seed, the plant or plant parts, arator, Heteronyx spp., Hylamorpha elegans, Hylotrupes the fruit or the soil in which the plants grow. bajulus, Hypera postica, Hypomeces squamosus, Hypothen 0222. The fact that the mixtures or compositions are well emus spp., Lachnosterna consanguinea, Lasioderma serri tolerated by plants at the concentrations required for control corne, Latheticus Oryzae, Lathridius spp., Lema spp., Lepti ling plant diseases allows the treatment of above-ground parts notarsa decemlineata, Leucoptera spp., Lissorhoptrus of plants, of propagation stock and seeds, and of the soil. Oryzophilus, Lixus spp., Luperodes spp., Lyctus spp., Megas 0223) The mixtures or compositions according to the celis spp., Melanotus spp., Melligethes aeneus, Melolontha invention, in combination with good plant tolerance and spp., Migdolus spp., Monochamus spp., Naupactus xan favourable toxicity to warm-blooded animals and being tol thographus, Necrobia spp., Niptus hololeucus, Oryctes rhi erated well by the environment, are suitable for protecting noceros, Oryzaephilus surinamensis, Oryzaphagus Oryzae, plants and plant organs, for increasing harvest yields, for Otiorrhynchus spp., Oxycetonia jucunda, Phaedon cochle improving the quality of the harvested material and for con ariae, Phyllophaga spp., Phyllophaga helleri, Phyllotreta trolling pests, in particular insects, arachnids, helminths, spp., Popillia japonica, Premnotrypes spp., ProStephanus nematodes and molluscs, which are encountered in agricul truncatus, Psylliodes spp., Ptinus spp., Rhizobius ventralis, ture, in horticulture, in animal husbandry, in forests, in gar Rhizopertha dominica, Sitophilus spp., Sitophilus Oryzae, dens and leisure facilities, in protection of stored products and Sphenophorus spp., Stegobium paniceum, Sternechus spp., US 2015/02824.83 A1 Oct. 8, 2015 27

Symphyletes spp., Tanymecus spp., Tenebrio molitor, Tene gri, Nephotettix spp., Nettigonicla spectra, Nilaparvata brioides mauretanicus, Tribolium spp., Trogoderma spp., lugens, Oncometopia spp., Orthezia praelonga, Oxya chin Tvchius spp., Xvlotrechus spp., Zabrus spp.; ensis, Pachypsylla spp., Parabemisia myricae, Paratrioza 0230 from the order Diptera, for example, Aedes spp., spp., Parlatoria spp., Pemphigus spp., Peregrinus maidis, Agromyza spp., Anastrepha spp., Anopheles spp., Phenacoccus spp., Phloeomyzus passerinii, Phorodon Asphondylia spp., Bactrocera spp., Bibio hortulanus, Calli humuli, Phylloxera spp., Pinnaspis aspidistrae, Planococcus phora erythrocephala, Caliphora vicina, Ceratitis capitata, spp., Prosopidopsylla flava, Protopulvinaria pyriformis, Chironomus spp., Chrysomyia spp., Chrysops spp., Chryso Pseudaulacaspis pentagona, Pseudococcus spp., Psyllopsis zona pluvialis, Cochliomyia spp., Contarinia spp., Cordylo spp., Psylla spp., Pteromalus spp., Pyrilla spp., Ouadraspid bia anthropophaga, Cricotopus Sylvestris, Culex spp., Culi iotus spp., Quesada gigas, Rastrococcus spp., Rhopalosi coides spp., Culiseta spp., Cuterebra spp., Dacus oleae, phum spp., Saissetia spp., Scaphoideus titanus, Schizaphis Dasy neura spp., Delftia spp., Dermatobia hominis, Droso graminum, Selenaspidus articulatus, Sogata spp., Sogatella phila spp., Echinocnemus spp., Fannia spp., Gasterophilus fircifera, Sogatodes spp., Stictocephala festina, Siphoninus spp., Glossina spp., Haematopota spp., Hydrelia spp., philly reae, Tenalaphara malavensis, Tetragonocephela spp., Hydrellia griseola, Hylenya spp., Hippobosca spp., Hypo Tinocallis caryaefoliae, Tomaspis spp., Toxoptera spp., Tri derma spp., Liriomyza spp., Lucilia spp., Lutzomyia spp., aleurodes vaporariorum, Trioza spp., Tiphlocyba spp., Unas Mansonia spp., Musca spp., Oestrus spp., Oscinella frit, pis spp., Viteus vitifolii, Zygina spp.; Paratanytarsus spp., Paralauterborniella subcincta, Pego 0233 from the order Hymenoptera, for example, myia spp., Phlebotomus spp., Phorbia spp., Phormia spp., Acromyrmex spp., Athalia spp., Atta spp., Diprion spp., Hop Piophila casei, Prodiplosis spp., Psila rosae, Rhagoletis spp., locampa spp., Lasius spp., Monomorium pharaonis, Sirex Sarcophaga spp., Simulium spp., Stomoxys spp., Tabanus spp., Solenopsis invicta, Tapinoma spp., Urocerus spp., Vespa spp., Tetanops spp., Tipula spp.; spp., Xeris spp.; 0231 from the order Heteroptera, for example, Anasa tris 0234 from the order Isopoda, for example, Armadillidium tis, Antestiopsis spp., Boisea spp., Blissus spp., Calocoris vulgare, Oniscus asellus, Porcellio scaber, spp., Campylomma livida, Cavelerius spp., Cimex spp., Col 0235 from the order Isoptera, for example, Coptotermes laria spp., Creontiades dilutus, Dasynus piperis, Dichelops spp., Cornitermes cumulans, Cryptotermes spp., Incisitermes fircatus, Diconocoris hewetti, Dysdercus spp., Euschistus spp., Microtermes Obesi, Odontotermes spp., Reticulitermes spp., Eurygaster spp., Heliopeltis spp., Horcias nobilellus, Spp., Leptocorisa spp., Leptocorisa varicornis, Leptoglossus phyl 0236 from the order Lepidoptera, for example, Achroia lopus, Lygus spp., Macropes excavatus, Miridae, Monalo grisella, Acronicta major; Adoxophyes spp., Aedia leu nion atratum, Nezara spp., Oebalus spp., Pentomidae, comelas, Agrotis spp., Alabama spp., Amyelois transitella, Piesma quadrata, Piezodorus spp., Psalus spp., Pseudacy.sta Anarsia spp., Anticarsia spp., Argyroploce spp., Barathra persea, Rhodnius spp., Sahlbergella singularis, Scaptocoris brassicae, Borbo cinnara, Bucculatrix thurberiella, Bupalus castanea, Scotinophora spp., Stephanitis nashi, Tibraca spp., piniarius, Busseola spp., Cacoecia spp., Caloptilia theivora, Triatoma spp.; Capua reticulana, Carpocapsapomonella, Carposina nipon 0232 from the order Homoptera, for example, Acizzia ensis, Cheimatobia brumata, Chilo spp., Choristoneura spp., acaciaebaileyanae, Acizzia dodonaeae, AcizZia uncatoides, Clysia ambiguella, Cnaphalocerus spp., Cnaphalocrocis Acrida turrita, Acyrthosipon spp., Acrogonia spp., Aeneola medinalis, Cnephasia spp., Conopomorpha spp., Conotrach mia spp., Agonoscena spp., Aleyrodes proletella, Aleurolobus elus spp., Copitarsia spp., Cydia spp., Dallaca noctuides, barodensis, Aleurothrixus floccosus, Allocaridara malayen Diaphania spp., Diatraea saccharalis, Earias spp., Ecdytolo sis, Amrasca spp., Anuraphis cardui, Aonidiella spp., Apha pha aurantium, Elasmopalpus lignosellus, Eldana saccha nostigma piri, Aphis spp., Arboridia apicalis, Arytainilla rina, Ephestia spp., Epinotia spp., Epiphyas postvittana, spp., Aspidiella spp., Aspidiotus spp., Atanus spp., Aula Etiella spp., Eulia spp., Eupoecilia ambiguella, Euproctis corthum Solani, Bemisia tabaci, Blastopsylla Occidentalis, spp., Euxoa spp., Feltia spp., Galleria mellonella, Gracillaria Boreioglycaspis melaleucae, Brachycaudus helichrysi, spp., Grapholitha spp., Hedylepta spp., Helicoverpa spp., Brachycolus spp., Brevicoryne brassicae, Cacopsylla spp., Heliothis spp., Hofmannophila pseudospretella, Homoeo Calligypona marginata, Carneocephalafiulgida, Ceratova Soma spp., Homona spp., Hyponomeuta padella, Kakivoria cuna lanigera, Cercopidae, Ceroplastes spp., Chaetosiphon flavofasciata, Laphygma spp., Laspeyresia molesta, Leucino fragaefolii, Chionaspis tegalensis, Chlorita Onuki, Chon des Orbonalis, Leucoptera spp., Lithocolletis spp., Litho dracris rosea, Chromaphis juglandicola, Chrysomphalus phane antennata, Lobesia spp., Loxagrotis albicosta, Lyman ficus, Cicadulina mbila, Coccomytilus halli, Coccus spp., tria spp., Lyonetia spp., Malacosoma neustria, Maruca Cryptomyzus ribis, CryptoneOssa spp., Ctenarvtaina spp., testulalis, Manstra brassicae, Melanitis leda, Mocis spp., Dalbulus spp., Dialeurodes citri, Diaphorina citri, Diaspis Monopis obviella, Mythinna separata, Nemapogon cloacel spp., Drosicha spp., Dysaphis spp., Dysmicoccus spp., lus, Nymphula spp., Oiketicus spp., Oria spp., Orthaga spp., Empoasca spp., Eriosoma spp., Erythroneura spp., Eucalyp Ostrinia spp., Oulema Oryzae, Panolis flammea, Parnara tolyma spp., Euphyllura spp., Euscelis bilobatus, Ferrisia spp., Pectinophora spp., Perileucoptera spp., Phthorimaea spp., Geococcus coffeae, Glycaspis spp., Heteropsylla spp., Phyllocnistis citrella, Phyllonorycter spp., Pieris spp., cubana, Heteropsylla spinulosa, Homalodisca coagulata, Platynota Stultana, Plodia interpunctella, Plusia spp., Plu Hyalopterus arundinis, Icerya spp., Idiocerus spp., Idiosco tella xylostella, Prays spp., Prodenia spp., Protoparce spp., pus spp., Laodelphax striatellus, Lecanium spp., Lepi Pseudaletia spp., Pseudaletia unipuncta, Pseudoplusia dosaphes spp., Lipaphis erysimi, Macrosiphum spp., Macros includens, Pyrausta nubilalis, Rachiplusia nu, Schoenobius teles facifions, Mahanarva spp., Melanaphis sacchari, spp., Scirpophaga spp., Scirpophaga innotata, Scotia seg Metcalfiella spp., Metopolophium dirhodium, Monellia cos etum, Sesamia spp., Sesamia inferens, Sparganothis spp., talis, Monelliopsis pecanis, Myzus spp., Nasonovia ribisini Spodoptera spp., Spodoptera praefica, Stathmopoda spp., US 2015/02824.83 A1 Oct. 8, 2015 28

Stomopteryx subsecivella, Synanthedon spp., Tecia 0247. It is furthermore possible to control organisms from Solanivora, Thermesia gemmatalis, Tinea cloacella, Tinea the subphylum Protozoa, especially from the order Coccidia, pellionella, Tineola bisselliella, Tortrix spp., Trichophaga Such as Eimeria spp. tapetzella, Trichoplusia spp., Tryporyza incertulas, Tuta 0248. The mixtures or compositions according to the absoluta, Virachola spp.; invention, are particular suitable for controlling pests infect 0237 from the order Orthoptera or Saltatoria, for ing soybean like Acrosternum hilare, Agrotis ipsilon, Calo example, Acheta domesticus, Dichroplus spp., Gryllotalpa mycterus setarius, Ceratoma trifurcata, Colaspis brunnea, spp., Hieroglyphus spp., Locusta spp., Melanoplus spp., Colaspis crimnicornis, Cyclocephala lurida, Dectes texanus, Schistocerca gregaria, Delfia platura, Epicauta finebris, Epicauta pennsylvanica, 0238 from the order Phthiraptera, for example, Dama Epicauta spp., Epicauta vittata, Euschistus spp., Feltia linia spp., Haematopinus spp., Linognathus spp., Pediculus ducens, Halticus bractatus, Hypena scabra, Melanoplus bivi spp., Ptirus pubis, Trichodectes spp.; tatus, Melanoplus differentialis, Melanoplus femurrubrum, Odontota horni, Papaipema nebris, Peridroma saucia, Phyl 0239 from the order Psocoptera for example Lepinatus lophaga Congrua, Phyllophaga implicita, Phyllophaga rug spp., LipOscelis spp.; Osa, Popillia japonica, Pseudoplusia includens, Spodoptera 0240 from the order Siphonaptera, for example, Cerato Ornithogalli, Strigoderma arbOricola, Tetranychus urticae, phyllus spp., Ctenocephalides spp., Pulex irritans, Tunga Vanessa Cardui. penetrans, Xenopsylla cheopsis, 0249. The mixtures or compositions according to the 0241 from the order Thysanoptera, for example, Anapho invention can also be used in the control of vectors. In the thrips obscurus, Baliothrips biformis, Drepanothrips reuteri, sense of the present invention, a vector is an arthropod, in Enneothrips flavens, Frankliniella spp., Heliothrips spp., particular an insector arachnid, capable of transferring patho Hercinothrips femoralis, Rhipiphorothrips cruentatus, Scir gens such as, for example, viruses, worms, single-cell organ tothrips spp., Taeniothrips cardamomi, Thrips spp.; isms and bacteria from a reservoir (plant, animal, human, etc.) 0242 from the order Zygentoma (=Thysanura), for to a host. The pathogens may either be transferred mechani example, Ctenolepisma spp., Lepisma saccharina, Lepis cally onto a host (for example trachoma by non-biting flies) or modes inquilinus, Thermobia domestica, transferred by injection into a host (for example malaria para 0243 from the class Symphyla, for example, Scutigerella sites by mosquitoes). Spp., 0250 Examples of vectors and the diseases or pathogens 0244 pests from the phylum Mollusca, especially from transferred by them are: the class Bivalvia, for example, Dreissena spp., and from the 0251 1) mosquitoes class Gastropoda, for example, Anion spp., Biomphalaria 0252) Anopheles: malaria, filariasis: spp., Bulinus spp., Deroceras spp., Galba spp., Lynnaea spp., 0253 Culex: Japanese encephalitis, filariasis, other viral Oncomelania spp., Pomacea spp., Succinea spp.; diseases, transfer of worms; 0245 animal pests from the phylums Plathelminthes and 0254 Aedes: yellow fever, Dengue fever, filariasis, other Nematoda, for example, Ancylostoma duodenale, Ancylos viral diseases; toma ceylanicum, Acylostoma braziliensis, Ancylostoma 0255 Simuliidae: transfer of worms, in particular spp., Ascaris spp., Brugia malayi, Brugia timori, Bunosto Onchocerca volvulus, mum spp., Chabertia spp., Clonorchis spp., Cooperia spp., 0256 2) Lice: skin infections, epidemic typhus; Dicrocoelium spp., Dictyocaulus filaria, Diphyllobothrium 0257 3) Fleas: plague, murine typhus; latum, Dracunculus medinensis, Echinococcus granulosus, 0258 4) Flies: sleeping sickness (trypanosomiasis); Echinococcus multilocularis, Enterobius vermicularis, cholera, other bacterial diseases; Faciola spp., Haemonchus spp., Heterakis spp., Hymenolepis 0259 5) Mites: Acariose, epidemic typhus, Rickettsi nana, Hvostrongulus spp., Loa Loa, Nematodirus spp., alpox, Tularamia, Saint-Louis encephalitis, tick-borne Oesophagostomum spp., Opisthorchis spp., Onchocerca vol encephalitis (TBE), Krim-Kongo haematologic fever, vulus, Ostertagia spp., Paragonimus spp., Schistosomen spp., epidemic typhus, borreliosis; Strongyloides fuelleborni, Strongyloides Stercoralis, Strony 0260 6) Ticks: Borelliosis such as Borrelia duttoni, loides spp., Taenia Saginata, Taenia Solium, Trichinella spi tick-borne encephalitis, Q fever (Coxiella burnetii), ralis, Trichinella nativa, Trichinella britovi, Trichinella nel babesiosis (Babesia canis canis). soni, Trichinella pseudopsiralis, Tricho strongulus spp., 0261 Examples of vectors in the sense of the present Trichuris trichuria, Wuchereria bancrofti, invention are insects such as aphids, flies, leafhoppers or 0246 phytoparasitic pests from the phylum Nematoda, for thrips, capable of transferring plant viruses to plants. Further example, Aphelenchoides spp., Bursaphelenchus spp., Dity vectors capable of transferring plant viruses are spider mites, lenchus spp., Globodera spp., Heterodera spp., Longidorus lice, beetles and nematodes. spp., Meloidogyne spp., Pratylenchus spp., Radopholus spp., 0262. Further examples of vectors in the sense of the Trichodorus spp., Tvlenchulus spp., Xiphinema spp., Heli present invention are insects and arachnids such as mosqui cotylenchus spp., Tilenchorhynchus spp., Scutellonema spp., toes, in particular of the genera Aedes, Anopheles, for Paratrichodorus spp., Meloinema spp., Paraphelenchus spp., example A. gambiae, A. arabiensis, A. funestus, A. dirus Agilenchus spp., Belonolaimus spp., Nacobbus spp., Rotylen (Malaria), and Culex, lice, fleas, flies, mites and ticks capable chulus spp., Rotylenchus spp., Neotylenchus spp., Paraph of transferring pathogens to animals and/or humans. elenchus spp., Dolichodorus spp., Hoplolaimus spp., Punc 0263. A control of vectors is also possible with resistance todera spp., Criconemella spp., Ouinisulcius spp., breaking compounds/compositions. Hemicycliophora spp., Anguina spp., Subanguina spp., 0264. Mixtures or compositions of the present invention Hemicriconenoides spp., Psilenchus spp., Pseudohalenchus are suitable for use in the prevention of diseases or of patho spp., CricOnemoides spp., Cacopaurus spp. gens transferred by vectors. Thus, a further aspect of the US 2015/02824.83 A1 Oct. 8, 2015 29 present invention is the use of compounds according to the Malvaceae sp. (e.g. okra, cocoa), Papaveraceae (e.g. poppy), invention for controlling vectors, e.g., in agriculture, in hor Asparagaceae (e.g. asparagus).; useful plants and ornamental ticulture, in forests, in gardens and leisure facilities as well as plants in the garden and woods including turf, lawn, grass and in the protection of stored products and materials. Stevia rebaudiana, and in each case genetically modified 0265 Plants types of these plants. 0266. According to the invention all plants and plant parts 0269. Soybeans are particularly preferred plants. can be treated. By plants is meant all plants and plant popu 0270. In particular, the mixtures and compositions accord lations such as desirable and undesirable wild plants, culti ing to the invention are Suitable for controlling the following vars and plant varieties (whether or not protectable by plant plant diseases: variety or plant breeder's rights). Cultivars and plant varieties 0271 Albugo spp. (white rust) on ornamental plants, Veg can be plants obtained by conventional propagation and etable crops (e.g. A. candida) and Sunflowers (e.g. A. trago breeding methods which can be assisted or Supplemented by pogonis); Alternaria spp. (black spot disease, black blotch) one or more biotechnological methods such as by use of on vegetables, oilseed rape (e.g. A. brassicola or A. brassi double haploids, protoplast fusion, random and directed cae), Sugar beet (e.g. A. tenuis), fruit, rice, soybeans and also mutagenesis, molecular or genetic markers or by bioengi on potatoes (e.g. A. Solani or A. alternata) and tomatoes (e.g. neering and genetic engineering methods. By plant parts is A. Solani or A. alternata) and Alternaria spp. (black head) on meant all above ground and below ground parts and organs of wheat, Aphanomyces spp. on Sugar beet and vegetables; plants such as shoot, leaf blossom and root, whereby for Ascochyta spp. on cereals and vegetables, e.g. A. tritici (Asco example leaves, needles, stems, branches, blossoms, fruiting chyta leafblight) on wheat and A. hordei on barley; Bipolaris bodies, fruits and seed as well as roots, corms and rhizomes and Drechslera spp. (teleomorph: Cochliobolus spp.), e.g. are listed. Crops and vegetative and generative propagating leaf spot diseases (D. maydis and B. Zeicola) on corn, e.g. material, for example cuttings, corms, rhizomes, runners and glume blotch (B. Sorokiniana) on cereals and e.g. B. Oryzae on seeds also belong to plant parts. rice and on lawn; Blumeria (old name: Erysiphe) graminis 0267. The inventive mixtures or compositions s, when (powdery mildew) on cereals (e.g. wheat or barley); Botry they are well tolerated by plants, have favourable homeo Osphaeria spp. (Slack Dead Arm Disease) on grapevines therm toxicity and are well tolerated by the environment, are (e.g. B. Obtusa); Botrytis cinerea (teleomorph: Botryotinia Suitable for protecting plants and plant organs, for enhancing fiiceliana. gray mold, gray rot) on Soft fruit and pomaceous harvest yields, for improving the quality of the harvested fruit (inter alia strawberries), vegetables (inter alia lettuce, material. They can preferably be used as crop protection carrots, celeriac and cabbage), oilseed rape, flowers, grape compositions. They are active against normally sensitive and vines, forest crops and wheat (ear mold); Bremia lactucae resistant species and against all or some stages of develop (downy mildew) on lettuce; Ceratocystis (syn. Ophiostoma) ment. spp. (blue stain fungus) on deciduous trees and coniferous 0268 Plants which can be treated in accordance with the trees, e.g. C. ulmi (Dutch elm disease) on elms; Cercospora invention include the following main crop plants maize, soya spp. (Cereospora leaf spot) on corn (e.g. C. zeae-maydis), bean, alfalfa, cotton, Sunflower, Brassica oil seeds such as rice, Sugar beet (e.g. C. beticola), Sugar cane, vegetables, Brassica napus (e.g. canola, rapeseed), Brassica rapa, B. coffee, Soybeans (e.g. C. Sojina or C. kikuchil) and rice; juncea (e.g. (field) mustard) and Brassica carinata, Cladosporium spp. on tomato (e.g. C. fulvum. tomato leaf Arecaceae sp. (e.g. oilpalm, coconut), rice, wheat, Sugar beet, mold) and cereals, e.g. C. herbarum (earrot) on wheat; Clavi Sugar cane, oats, rye, barley, millet and sorghum, triticale, ceps purpurea (ergot) on cereals; Cochliobolus (anamorph: flax, nuts, grapes and vine and various fruit and vegetables Helminthosporium or Bipolaris) spp. (leaf spot) on corn (e.g. from various botanic taxa, e.g. Rosaceae sp. (e.g. pome fruits C. carbonum), cereals (e.g. C. sativus, anamorph: B. Soro Such as apples and pears, but also stone fruits such as apricots, kiniana. glume blotch) and rice (for example C. miyabeanus, cherries, almonds, plums and peaches, and berry fruits such anamorph: H. Oryzae); Colletotrichum (teleomorph: Glomer as strawberries, raspberries, red and black currant and goose ella) spp. (anthracnosis) on cotton (e.g. C. gossypii), corn berry), Ribesioidae sp., Juglandaceae sp., Betulaceae sp., (e.g. C. graminicola. Stem rot and anthracnosis), soft fruit, Anacardiaceae sp., Fagaceae sp., Moraceae sp., Oleaceae potatoes (e.g. C. coccodes. wilt disease), beans (e.g. C. lin sp. (e.g. olive tree), Actinidaceae sp., Lauraceae sp. (e.g. demuthianum) and Soybeans (e.g. C. truncatum); Corticium avocado, cinnamon, camphor), Musaceae sp. (e.g. banana spp., e.g. C. Sasakii (sheath blight) on rice; Corynespora trees and plantations), Rubiaceae sp. (e.g. coffee), Theaceae cassicola (leaf spot) on Soybeans and ornamental plants; sp. (e.g. tea), Sterculiceae sp., Rutaceae sp. (e.g. lemons, Cycloconium spp., e.g. C. Oleaginum on olives; Cylindrocar oranges, mandarins and grapefruit); Solanaceae sp. (e.g. pon spp. (e.g. fruit tree cancer or black foot disease of grape tomatoes, potatoes, peppers, capsicum, aubergines, tobacco), vine, teleomorph: Nectria or Neonectria spp.) on fruit trees, Liliaceae sp., Compositae sp. (e.g. lettuce, artichokes and grapevines (e.g. C. liriodendin, teleomorph: Neonectria liri chicory—including root chicory, endive or common Odendri, black foot disease) and many ornamental trees; chicory), Umbelliferae sp. (e.g. carrots, parsley, celery and Dematophora (teleomorph: Rosellinia) necatrix (root/stem celeriac), Cucurbitaceae sp. (e.g. cucumbers including gher rot) on Soybeans; Diaporthe spp. e.g. D. phaseolorum (stem kins, pumpkins, watermelons, calabashes and melons), Alli disease) on Soybeans; Drechslera (syn. Helminthosporium, aceae sp. (e.g. leeks and onions), Cruciferae sp. (e.g. white teleomorph: Pyrenophora) spp. on corn, cereals, such as bar cabbage, red cabbage, broccoli, cauliflower, Brussels sprouts, ley (e.g. D. teres, net blotch) and on wheat (e.g. D. tritici pak choi, kohlrabi, radishes, horseradish, cress and chinese repentis. DTR leaf spot), rice and lawn; Escadisease (dieback cabbage), Leguminosae sp. (e.g. peanuts, peas, lentils and of grapevine, apoplexia) on grapevines, caused by Formiti beans e.g. common beans and broadbeans), Chenopodiaceae poria (syn. Phellinus) punctata, F. mediterranea. Phaeomo sp. (e.g. Swiss chard, fodder beet, spinach, beetroot), niella chlamydospora (old name Phaeoacremonium chlamy Linaceae sp. (e.g. hemp), Cannabeacea sp. (e.g. cannabis), dosporum), Phaeoacremonium aleophilum and/or US 2015/02824.83 A1 Oct. 8, 2015 30

Botryosphaeria obtusa, Elsinoe spp. on pome fruit (E. pyri) species or P. humili on hops; Pseudopezicula tracheiphila and Soft fruit (E. veneta. anthracnosis) and also grapevines (angular leaf scorch, anamorph Phialophora) on grapevines; (E. ampelina. anthracnosis); Entvloma Oryzae (leaf Smut) on Puccinia spp. (rust disease) on various plants, e.g. P. triticina rice: Epicoccum spp. (black head) on wheat; Erysiphe spp. (brown rust of wheat), P Striiformis (yellow rust). P hordei (powdery mildew) on Sugar beet (E. betae), vegetables (e.g. (dwarf leaf rust), P. graminis (black rust) or P recondita E. pisi), Such as cucumber species (e.g. E. cichoracearum) (brown rust of rye) on cereals. Such as e.g. wheat, barley or and cabbage species, such as oilseed rape (e.g. E. crucifer rye. P. kuehnii on Sugar cane and, e.g., on asparagus (e.g. P. arum); Eutypa fata (Eutypa cancer or dieback, anamorph: asparagi); Pyrenophora (anamorph: Drechslera) tritici-re Cytosporina lata, syn. Libertella blepharis) on fruit trees, pentis (speckled leaf blotch) on wheat or P teres (net blotch) grapevines and many ornamental trees: Exserohilum (syn. on barley; Pyricularia spp., e.g. P. Oryzae (teleomorph: Mag Helminthosporium) spp. on corn (e.g. E. turcicum); Fusarium naporthe grisea. rice blast) on rice and P. grisea on lawn and (teleomorph: Gibberella) spp. (wilt disease, root and stem cereals; Pythium spp. (damping-off disease) on lawn, rice, rot) on various plants, such as e.g. F. graminearum or F. corn, wheat, cotton, oilseed rape, Sunflowers, Sugar beet, Veg culmorum (root rot and silver-top) on cereals (e.g. wheat or etables and other plants (e.g. P. ultimum or P aphanidenna barley), F. Oxysporum on tomatoes, F. Solani on Soybeans and tum); Ranularia spp., e.g. R. Colocygni (Ranularia leaf and F. verticillioides on corn; Gaeumannomyces graminis lawn spot/physiological leaf spot) on barley and R. beticola (takeall) on cereals (e.g. wheat or barley) and corn; Gibber on Sugar beet; Rhizoctonia spp. on cotton, rice, potatoes, ella spp. on cereals (e.g. G. Zeae) and rice (e.g. G. fijikuroi: lawn, corn, oilseed rape, potatoes, Sugar beet, vegetables and bakanae disease); Glomerellacingulata on grapevines, poma on various other plants, for example R. Solani (root and stern ceous fruit and other plants and G. gossypii on cotton; grain rot) on Soybeans, R. Solani (sheath blight) on rice or R. cerea staining complex on rice; Guignardia bidwelli (black rot) on lis (sharp eyespot) on wheat or barley; Rhizopus stolonifer grapevines; Gymnosporangium spp. on Rosaceae and juni (soft rot) on Strawberries, carrots, cabbage, grapevines and per, e.g. G. Sabinae (pear rust) on pears; Helminthosporium tomato; Rhynchosporium secalis (leaf spot) on barley, rye and spp. (syn. Drechslera, teleomorph: Cochliobolus) on corn, triticale; Sarocladium Oryzae and S. attenuatum (sheath rot) cereals and rice; Hemileia spp., e.g. H. vastatrix (coffee leaf on rice: Sclerotinia spp. (stem or white rot) on vegetable and rust) on coffee; Isariopsis clavispora (syn. Cladosporium field crops, such as oilseed rape, Sunflowers (e.g. Sclerotinia vitis) on grapevines; Macrophomina phaseolina (syn. sclerotiorum) and Soybeans (e.g. S. rolfsii), Septoria spp. on phaseoli) (root/stem rot) on Soybeans and cotton; Micro various plants, e.g. S. glycines (leaf spot) on Soybeans, S. dochium (syn. Fusarium) nivale (pink Snow mold) on cereals tritici (Septoria leaf blotch) on wheat and S. (syn. Stagono (e.g. wheat or barley); Microsphaera diffusa (powdery mil spora) nodorum (leaf blotch and glume blotch) on cereals; dew) on Soybeans; Monilinia spp., e.g. M. laxa. M. fructicola Uncinula (syn. Erysiphe) necator (powdery mildew, and M. fructigena (blossom and twig blight) on Stone fruit and anamorph: Oidium tuckeri) on grapevines; Setospaeria spp. other Rosaceae, Mycosphaerella spp. on cereals, bananas, (leaf spot) on corn (e.g. S. turcicum, syn. Helminthosporium Soft fruit and peanuts, such as e.g. M. graminicola (anamorph: turcicum) and lawn; Sphacelotheca spp. (head Smut) on corn, Septoria tritici, Septoria leaf blotch) on wheat or M. fijiensis (e.g. S. reiliana. kernel Smut), millet and Sugar cane; (Sigatoka disease) on bananas; Peronospora spp. (downy mil Sphaerotheca fitliginea (powdery mildew) on cucumber spe dew) on cabbage (e.g. P. brassicae), oilseed rape (e.g. P cies; Spongospora subterranea (powdery scab) on potatoes parasitica), bulbous plants (e.g. P. destructor), tobacco (P and the viral diseases transmitted thereby; Stagonospora spp. tabacina) and Soybeans (e.g. P. manshurica); Phakopsora on cereals, e.g. S. nodorum (leaf blotch and glume blotch, pachyrhizi and P. meibomiae (soybean rust) on Soybeans; teleomorph: Leptosphaeria syn. Phaeosphaerial nodorum) Phialophora spp. e.g. on grapevines (e.g. P tracheiphila and on wheat; Synchytrium endobioticum on potatoes (potato P. tetraspora) and Soybeans (e.g. P. gregata. Stem disease); wart disease); Taphrina spp., e.g. T. deformans (curly-leaf Phoma lingam (root and stem rot) on oilseed rape and cab disease) on peach and T. pruni (plum-pocket disease) on pi bage and P betae (leaf spot) on Sugar beet; Phomopsis spp. on ums; Thielaviopsis spp. (black root rot) on tobacco, pome Sunflowers, grapevines (e.g. P. viticola. dead-arm disease) fruit, vegetable crops, soybeans and cotton, e.g. T. basicola and Soybeans (e.g. stem canker/stem blight: P phaseoli, (syn. Chalara elegans); Tilletia spp. (bunt or Stinking Smut) teleomorph: Diaporthe phaseolorum); Physodenna maydis on cereals, such as e.g. T. tritici (syn. T. caries, wheat bunt) (brown spot) on corn; Phytophthora spp. (wilt disease, root, and T. controversa (dwarfbunt) on wheat; Tiphula incarnate leaf stem and fruit rot) on various plants, such as on bell (gray Snow mold) on barley or wheat, Urocystis spp., e.g. U. peppers and cucumber species (e.g. P. capsici), soybeans (e.g. occulta (flag Smut) on rye; Uromyces spp. (rust) on vegetable P. megasperma, syn. Psoiae), potatoes and tomatoes (e.g. P plants, such as beans (e.g. U. appendiculatus, syn. U. infestans. late blight and brown rot) and deciduous trees (e.g. phaseoll) and Sugar beet (e.g. U. betae); Ustilago spp. (loose P ranorum Sudden oak death); Plasmodiophora brassicae Smut) on cereals (e.g. U. nuda and U. avaenae), corn (e.g. U. (club-root) on cabbage, oilseed rape, radish and other plants; maydis, corn Smut) and Sugar cane; Venturia spp. (scab) on Plasmopara spp., e.g. P. viticola (peronospora of grapevines, apples (e.g. Vinaequalis) and pears and Verticillium spp. (leaf downy mildew) on grapevines and Phalstedii on Sunflowers; and shoot wilt) on various plants, such as fruit trees and Podosphaera spp. (powdery mildew) on Rosaceae, hops, ornamental trees, grapevines, Soft fruit, vegetable and field pomaceaus fruit and soft fruit, e.g. P. leucotricha on apple; crops, such as e.g. V. dahliae on Strawberries, oilseed rape, Polymyxa spp., e.g. on cereals, such as barley and wheat (P potatoes and tomatoes. graminis) and Sugar beet (P. betae) and the viral diseases 0272. The mixtures and compositions according to the transmitted thereby; Pseudocercosporella herpotrichoides present inventions are in particular preferred for controlling (eyespot/stem break, teleomorph: Tapesia vallundae) on the following plant diseases: Soybean diseases: Cercospora cereals. e.g. wheat or barley; Pseudoperonospora (downy kikuchii, Elsinoeglycines, Diaporthe phaseolorum var. Sojae, mildew) on various plants, e.g. P. cubensis on cucumber Septaria glycines, Cercospora Sojina, Phakopsora US 2015/02824.83 A1 Oct. 8, 2015 31 pachyrhizi, Phytophthora sojae, Rhizoctonia Solani, harvest. It is also possible to positively influence the produc Corynespora casicola, and Sclerotinia Sclerotiorum. tion or the elimination of secondary plant ingredients. One (0273 Plant Growth Regulation example is the stimulation of the flow of latex in rubber trees. 0274. In some cases, the inventive mixtures or composi 0282 Under the influence of growth regulators, partheno tions can, at particular concentrations or application rates, carpic fruits may be formed. In addition, it is possible to also be used as herbicides, safeners, growth regulators or influence the sex of the flowers. It is also possible to produce agents to improve plant properties, or as microbicides, for sterile pollen, which is of great importance in the breeding example as fungicides, antimycotics, bactericides, viricides and production of hybrid seed. (including compositions against Viroids) or as compositions 0283 Use of growth regulators can control the branching against MLO (Mycoplasma-like organisms) and RLO (Rick of the plants. On the one hand, by breaking apical dominance, ettsia-like organisms). The active ingredients of the inventive it is possible to promote the development of side shoots, mixture or composition intervene in the metabolism of the which may be highly desirable particularly in the cultivation plants and can therefore also be used as growth regulators. of ornamental plants, also in combination with an inhibition 0275 Plant growth regulators may exert various effects on of growth. On the other hand, however, it is also possible to plants. The effect of the substances depends essentially on the inhibit the growth of the side shoots. This effect is of particu time of application in relation to the developmental stage of lar interest, for example, in the cultivation of tobacco or in the the plant, and also on the amounts of active ingredient applied cultivation of tomatoes. to the plants or their environment and on the type of applica 0284 Under the influence of growth regulators, the tion. In each case, growth regulators should have a particular amount of leaves on the plants can be controlled Such that desired effect on the crop plants. defoliation of the plants is achieved at a desired time. Such 0276 Plant growth-regulating compounds can be used, for defoliation plays a major role in the mechanical harvesting of example, to inhibit the vegetative growth of the plants. Such cotton, but is also of interest for facilitating harvesting in inhibition of growth is of economic interest, for example, in other crops, for example in Viticulture. Defoliation of the the case of grasses, since it is thus possible to reduce the plants can also be undertaken to lower the transpiration of the frequency of grass cutting in ornamental gardens, parks and plants before they are transplanted. sport facilities, on roadsides, at airports or in fruit crops. Also 0285 Growth regulators can likewise be used to regulate of significance is the inhibition of the growth of herbaceous fruit dehiscence. On the one hand, it is possible to prevent and woody plants on roadsides and in the vicinity of pipelines premature fruit dehiscence. On the other hand, it is also pos or overhead cables, or quite generally in areas where vigorous sible to promote fruit dehiscence or even flower abortion to plant growth is unwanted. achieve a desired mass (“thinning'), in order to eliminate 0277 Also important is the use of growth regulators for alternation. Alternation is understood to mean the character inhibition of the longitudinal growth of cereal. This reduces istic of some fruit species, for endogenous reasons, to deliver or completely eliminates the risk of lodging of the plants prior very different yields from year to year Finally, it is possible to to harvest. In addition, growth regulators in the case of cereals use growth regulators at the time of harvest to reduce the can strengthen the culm, which also counteracts lodging. The forces required to detach the fruits, in order to allow mechani employment of growth regulators for shortening and cal harvesting or to facilitate manual harvesting. strengthening culms allows the deployment of higher fertil 0286 Growth regulators can also be used to achieve faster izer Volumes to increase the yield, without any risk of lodging or else delayed ripening of the harvested material before or of the cereal crop. after harvest. This is particularly advantageous as it allows 0278. In many crop plants, inhibition of vegetative growth optimal adjustment to the requirements of the market. More allows denser planting, and it is thus possible to achieve over, growth regulators in some cases can improve the fruit higher yields based on the soil surface. Another advantage of colour. In addition, growth regulators can also be used to the Smallerplants obtained in this way is that the crop is easier concentrate maturation within a certain period of time. This to cultivate and harvest. establishes the prerequisites for complete mechanical or 0279. Inhibition of the vegetative plant growth may also manual harvesting in a single operation, for example in the lead to enhanced yields because the nutrients and assimilates case of tobacco, tomatoes or coffee. are of more benefit to flower and fruit formation than to the 0287. By using growth regulators, it is additionally pos Vegetative parts of the plants. sible to influence the resting of seed or buds of the plants, such 0280 Frequently, growth regulators can also be used to that plants such as pineapple or ornamental plants in nurser promote vegetative growth. This is of great benefit when ies, for example, germinate, Sprout or flower at a time when harvesting the vegetative plant parts. However, promoting they are normally not inclined to do so. In areas where there Vegetative growth may also promote generative growth in that is a risk of frost, it may be desirable to delay budding or more assimilates are formed, resulting in more or larger fruits. germination of seeds with the aid of growth regulators, in 0281. In some cases, yield increases may be achieved by order to avoid damage resulting from late frosts. manipulating the metabolism of the plant, without any detect 0288 Finally, growth regulators can induce resistance of able changes in vegetative growth. In addition, growth regu the plants to frost, drought or high salinity of the soil. This lators can be used to alter the composition of the plants, which allows the cultivation of plants in regions which are normally in turn may result in an improvement in quality of the har unsuitable for this purpose. Vested products. For example, it is possible to increase the 0289 Resistance Induction/Plant Health and Other Sugar content in Sugar beet, Sugar cane, pineapples and in Effects citrus fruit, or to increase the protein content in Soya or 0290 The mixtures or compositions according to the cereals. It is also possible, for example, to use growth regu invention also exhibit a potent strengthening effect in plants. lators to inhibit the degradation of desirable ingredients, for Accordingly, they can be used for mobilizing the defenses of example Sugar in Sugar beet or Sugar cane, before or after the plant against attack by undesirable microorganisms. US 2015/02824.83 A1 Oct. 8, 2015

0291 Plant-strengthening (resistance-inducing) sub Sugar/acid ratio (Brix), polyphenols, starch content, nutri stances are to be understood as meaning, in the present con tional quality, gluten content/index, energy content, taste, text, those Substances which are capable of stimulating the etc., defense system of plants in Such a way that the treated plants, 0303 and further comprising decreased undesired ingre when Subsequently inoculated with undesirable microorgan dients such as e.g. less mycotoxines, less aflatoxines, isms, develop a high degree of resistance to these microor geosmin level, phenolic aromas, lacchase, polyphenol oxi ganisms. dases and peroxidases, nitrate content etc. 0292. The active compounds according to the invention 0304 Sustainable agriculture, comprising nutrient use are also suitable for increasing the yield of crops. In addition, efficiency, especially nitrogen (N)-use efficiency, phosphours they show reduced toxicity and are well tolerated by plants. (P)-use efficiency, water use efficiency, improved transpira 0293. Further, in context with the present invention plant tion, respiration and/or CO assimilation rate, better nodula physiology effects comprise the following: tion, improved Ca-metabolism etc. 0294 Abiotic stress tolerance, comprising temperature 0305 Delayed senescence, comprising improvement of tolerance, drought tolerance and recovery after drought plant physiology which is manifested, for example, in a stress, water use efficiency (correlating to reduced water con longer grain filling phase, leading to higher yield, a longer Sumption), flood tolerance, oZone stress and UV tolerance, duration of green leaf colouration of the plant and thus com tolerance towards chemicals like heavy metals, salts, pesti prising colour (greening), water content, dryness etc. Accord cides (safener) etc. ingly, in the context of the present invention, it has been found 0295 Biotic stress tolerance, comprising increased fungal that the specific inventive application of the active compound resistance and increased resistance against nematodes, combination makes it possible to prolong the green leaf area viruses and bacteria. In context with the present invention, duration, which delays the maturation (senescence) of the biotic stress tolerance preferably comprises increased fungal plant. The main advantage to the farmer is a longer grain resistance and increased resistance against nematodes filling phase leading to higher yield. There is also an advan 0296 Increased plant vigor, comprising plant health/plant tage to the farmer on the basis of greater flexibility in the quality and seed vigor, reduced stand failure, improved harvesting time. appearance, increased recovery, improved greening effect 0306 Therein "sedimentation value' is a measure for pro and improved photosynthetic efficiency. tein quality and describes according to Zeleny (Zeleny Value) 0297 Effects on plant hormones and/or functional the degree of sedimentation of flour Suspended in a lactic acid enzymes. Solution during a standard time interval. This is taken as a 0298 Effects on growth regulators (promoters), compris measure of the baking quality. Swelling of the gluten fraction ing earlier germination, better emergence, more developed offlour in lactic acid solution affects the rate of sedimentation root system and/or improved root growth, increased ability of of a flour Suspension. Both a higher gluten content and a tillering, more productive tillers, earlier flowering, increased better gluten quality give rise to slower sedimentation and plant height and/or biomass, shorting of stems, improvements higher Zeleny test values. The sedimentation value of flour in shoot growth, number of kernels/ear, number of ears/m, depends on the wheat protein composition and is mostly number of stolons and/or number of flowers, enhanced har correlated to the protein content, the wheat hardness, and the Vest index, bigger leaves, less dead basal leaves, improved Volume of pan and hearth loaves. A stronger correlation phyllotaxy, earlier maturation/earlier fruit finish, homog between loaf volume and Zeleny sedimentation volume com enous riping, increased duration of grain filling, better fruit pared to SDS sedimentation volume could be due to the finish, bigger fruit/vegetable size, sprouting resistance and protein content influencing both the volume and Zeleny value reduced lodging. (Czech. J. Food Sci. Vol. 21, No. 3: 91-96, 2000). 0307 Further the “falling number as mentioned herein is 0299 Increased yield, referring to total biomass per hect a measure for the baking quality of cereals, especially of are, yield per hectare, kernel/fruit weight, seed size and/or wheat. The falling number test indicates that sprout damage hectolitre weight as well as to increased product quality, may have occurred. It means that changes to the physical comprising: properties of the starch portion of the wheat kernel has 0300 improved processability relating to size distribution already happened. Therein, the falling number instrument (kernel, fruit, etc.), homogenous riping, grain moisture, better analyzes viscosity by measuring the resistance of a flour and milling, better vinification, better brewing, increased juice water paste to a falling plunger. The time (in seconds) for this yield, harvestability, digestibility, sedimentation value, fall to happen is known as the falling number. The falling number ing number, pod stability, storage stability, improved fiber results are recorded as an index of enzyme activity in a wheat length/strength/uniformity, increase of milk and/or meet or flour sample and results are expressed in time as seconds. quality of silage fed animals, adaption to cooking and frying: A high falling number (for example, above 300 seconds) 0301 further comprising improved marketability relating indicates minimal enzyme activity and sound quality wheator to improved fruit/grain quality, size distribution (kernel, fruit, flour. A low falling number (for example, below 250 seconds) etc.), increased storage/shelf-life, firmness/softness, taste indicates Substantial enzyme activity and sprout-damaged (aroma, texture, etc.), grade (size, shape, number of berries, wheat or flour. etc.), number ofberries/fruits per bunch, crispness, freshness, (0308. The term “more developed root system"/"improved coverage with wax, frequency of physiological disorders, root growth refers to longer root system, deeper root growth, colour, etc.; faster root growth, higher root dry/fresh weight, higher root 0302) further comprising increased desired ingredients Volume, larger root Surface area, bigger root diameter, higher Such as e.g. protein content, fatty acids, oil content, oil qual root stability, more root branching, higher number of root ity, aminoacid composition, Sugar content, acid content (pH), hairs, and/or more root tips and can be measured by analyzing US 2015/02824.83 A1 Oct. 8, 2015

the root architecture with Suitable methodologies and Image 0318. The invention further relates to seed which has been analysis programmes (e.g. WinRhizo). treated by one of the methods described in the previous para 0309 The term “crop water use efficiency” refers techni graph. The inventive seeds are employed in methods for the cally to the mass of agriculture produce per unit water con protection of seed from harmful microorganisms or pests. In Sumed and economically to the value of product(s) produced these methods, seed treated with at least one inventive mix per unit water Volume consumed and can e.g. be measured in ture or composition is used. terms of yield perha, biomass of the plants, thousand-kernel 0319. The inventive mixtures or compositions are also mass, and the number of ears per m2. Suitable for treating seed. A large part of the damage to crop 0310. The term "nitrogen-use efficiency” refers techni plants caused by harmful organisms is triggered by the infec cally to the mass of agriculture produce per unit nitrogen tion of the seed during storage or after Sowing, and also during consumed and economically to the value of product(s) pro and after germination of the plant. This phase is particularly duced per unit nitrogen consumed, reflecting uptake and ulti critical since the roots and shoots of the growing plant are lization efficiency. particularly sensitive, and even minor damage may result in 0311 Improvement in greening/improved colour and the death of the plant. There is therefore a great interest in improved photosynthetic efficiency as well as the delay of protecting the seed and the germinating plant by using appro senescence can be measured with well-known techniques priate compositions. Such as a Handy Pea System (Hansatech). Fv/Fm is a param 0320. The control of phytopathogenic fungi by treating the eter widely used to indicate the maximum quantum efficiency seed of plants has been known for a long time and is the of photosystem II (PSII). This parameteris widely considered subject of constant improvements. However, the treatment of to be a selective indication of plant photosynthetic perfor seed entails a series of problems which cannot always be mance with healthy samples typically achieving a maximum Solved in a satisfactory manner For instance, it is desirable to Fv/Fm value of approx. 0.85. Values lower than this will be develop methods for protecting the seed and the germinating observed if a sample has been exposed to some type of biotic plant, which dispense with, or at least significantly reduce, the or abiotic stress factor which has reduced the capacity for additional deployment of crop protection compositions after photochemical quenching of energy within PSII. Fv/Fm is planting or after emergence of the plants. It is also desirable to presented as a ratio of variable fluorescence (Fv) over the optimize the amount of the active ingredient used so as to maximum fluorescence value (Fm). The Performance Index provide the best possible protection for the seed and the is essentially an indicator of Sample vitality. (See e.g. germinating plant from attack by phytopathogenic fungi, but Advanced Techniques in Soil Microbiology, 2007. 11, 319 without damaging the plant itself by the active ingredient 341; Applied Soil Ecology, 2000, 15, 169-182.) employed. In particular, methods for the treatment of seed 0312 The improvement in greening/improved colour and should also take account of the intrinsic fungicidal properties improved photosynthetic efficiency as well as the delay of of transgenic plants in order to achieve optimal protection of senescence can also be assessed by measurement of the net the seed and the germinating plant with a minimum expendi photosynthetic rate (Pn), measurement of the chlorophyll ture of crop protection compositions. content, e.g. by the pigment extraction method of Ziegler and 0321. The present invention therefore also relates to a Ehle, measurement of the photochemical efficiency (Fv/Fm method for protection of seed and germinating plants from ratio), determination of shoot growth and final root and/or attack by phytopathogenic fungi and pests by treating the canopy biomass, determination of tiller density as well as of seed with an inventive composition. The invention likewise root mortality. relates to the use of the inventive compositions for treatment 0313 Within the context of the present invention prefer of seed to protect the seed and the germinating plant from ence is given to improving plant physiology effects which are phytopathogenic fungi and pests. The invention further selected from the group comprising: enhanced root growth/ relates to seed which has been treated with an inventive com more developed root system, improved greening, improved position for protection from phytopathogenic fungi. water use efficiency (correlating to reduced water consump 0322 The control of phytopathogenic fungi and pests tion), improved nutrient use efficiency, comprising especially which damage plants post-emergence is effected primarily by improved nitrogen (N)-use efficiency, delayed senescence treating the soil and the above-ground parts of plants with and enhanced yield. crop protection compositions. Owing to the concerns regard 0314 Within the enhancement of yield preference is given ing a possible influence of the crop protection compositions as to an improvement in the sedimentation value and the on the environment and the health of humans and animals, falling number as well as to the improvement of the protein there are efforts to reduce the amount of active ingredients and Sugar content especially with plants selected from the deployed. group of cereals (preferably wheat). 0323. One of the advantages of the present invention is that 0315 Preferably the novel use of the fungicidal mixtures the particular systemic properties of the inventive mixtures or or compositions of the present invention relates to a combined compositions mean that treatment of the seed with these use of a) preventively and/or curatively controlling patho active ingredients and compositions not only protects the seed genic fungi, with or without resistance management, and b)at itself, but also the resulting plants after emergence, from least one of enhanced root growth, improved greening, phytopathogenic fungi and pests. In this way, the immediate improved water use efficiency, delayed senescence and treatment of the crop at the time of sowing or shortly there enhanced yield. From group b) enhancement of root system, after can be dispensed with. water use efficiency and N-use efficiency is particularly pre 0324. It is likewise considered to be advantageous that the ferred. inventive mixtures or compositions can especially also be 0316 Seed Treatment used with transgenic seed, in which case the plant growing 0317 The invention further comprises a method for treat from this seed is capable of expressing a protein which acts ing seed. against pests. By virtue of the treatment of such seed with the US 2015/02824.83 A1 Oct. 8, 2015 34 inventive mixtures or compositions, merely the expression of sions, powders, foams, slurries or other coating compositions the protein, for example an insecticidal protein, can control for seed, and also ULV formulations. certain pests. Surprisingly, a further synergistic effect can be 0331. These formulations are prepared in a known man observed in this case, which additionally increases the effec ner, by mixing the active ingredients with customary addi tiveness for protection against attack by pests. tives, for example customary extenders and also solvents or 0325 The inventive compositions are suitable for protect diluents, dyes, wetting agents, dispersants, emulsifiers, anti ing seed of any plant variety which is used in agriculture, in foams, preservatives, secondary thickeners, adhesives, gib greenhouses, in forests or in horticulture and Viticulture. In berellins and also water. particular, this is the seed of cereals (such as wheat, barley, 0332 Useful dyes which may be present in the seed dress rye, triticale, sorghum/millet and oats), maize, cotton, Soya ing formulations usable in accordance with the invention are beans, rice, potatoes, Sunflower, bean, coffee, beet (for all dyes which are customary for Such purposes. It is possible example Sugar beet and fodder beet), peanut, oilseed rape, to use either pigments, which are sparingly soluble in water, poppy, olive, coconut, cocoa, Sugar cane, tobacco, Vegetables or dyes, which are soluble in water. Examples include the (such as tomato, cucumbers, onions and lettuce), turf and dyes known by the names Rhodamine B, C.I. Pigment Red ornamentals (see also below). The treatment of the seed of 112 and C.I. Solvent Red 1. cereals (such as wheat, barley, rye, triticale and oats), maize 0333 Useful wetting agents which may be present in the and rice is of particular significance. seed dressing formulations usable in accordance with the 0326. As also described below, the treatment of transgenic invention are all Substances which promote wetting and seed with the inventive mixtures or compositions is of par which are conventionally used for the formulation of active ticular significance. This relates to the seed of plants contain agrochemical ingredients. Preference is given to using alkyl ing at least one heterologous gene which enables the expres naphthalenesulphonates, such as diisopropyl or diisobutyl sion of a polypeptide or protein having insecticidal naphthalenesulphonates. properties. The heterologous gene in transgenic seed can 0334. Useful dispersants and/or emulsifiers which may be originate, for example, from microorganisms of the species present in the seed dressing formulations usable in accor Bacillus, Rhizobium, Pseudomonas, Serratia, Trichoderma, dance with the invention are all nonionic, anionic and cationic Clavibacter, Glomus or Gliocladium. This heterologous gene dispersants conventionally used for the formulation of active preferably originates from Bacillus sp., in which case the agrochemical ingredients. Usable with preference are non gene product is effective against the European maize borer ionic or anionic dispersants or mixtures of nonionic or and/or the Western maize rootworm. The heterologous gene anionic dispersants. Suitable nonionic dispersants include more preferably originates from Bacillus thuringiensis. especially ethylene oxide?propylene oxide block polymers, alkylphenol polyglycol ethers and tristryrylphenol polygly 0327. In the context of the present invention, the inventive col ether, and the phosphated or sulphated derivatives thereof. mixtures or compositions are applied to the seed alone or in a Suitable anionic dispersants are especially lignoSulphonates, suitable formulation. Preferably, the seed is treated in a state polyacrylic acid salts and arylsulphonate/formaldehyde con in which it is sufficiently stable for no damage to occur in the course of treatment. In general, the seed can be treated at any densates. time between harvest and Sowing. It is customary to use seed 0335 Antifoams which may be present in the seed dress which has been separated from the plant and freed from cobs, ing formulations usable in accordance with the invention are shells, stalks, coats, hairs or the flesh of the fruits. For all foam-inhibiting Substances conventionally used for the example, it is possible to use seed which has been harvested, formulation of active agrochemical ingredients. Silicone anti cleaned and dried downto a moisture content of less than 15% foams and magnesium Stearate can be used with preference. by weight. Alternatively, it is also possible to use seed which, 0336 Preservatives which may be present in the seed dressing formulations usable in accordance with the inven after drying, for example, has been treated with water and tion are all Substances usable for Such purposes in agrochemi then dried again. cal compositions. Examples include dichlorophene and ben 0328. When treating the seed, care must generally be taken Zyl alcohol hemiformal. that the amount of the inventive composition applied to the 0337 Secondary thickeners which may be present in the seed and/or the amount of further additives is selected such seed dressing formulations usable in accordance with the that the germination of the seed is not impaired, or that the invention are all Substances usable for Such purposes in agro resulting plant is not damaged. This has to be borne in mind in chemical compositions. Preferred examples include cellulose particular in the case of mixtures or compositions which can derivatives, acrylic acid derivatives, Xanthan, modified clays have phytotoxic effects at certain application rates. and finely divided silica. 0329. The inventive mixtures or compositions can be 0338 Adhesives which may be present in the seed dress applied directly, i.e. without containing any other compo ing formulations usable in accordance with the invention are nents and without having been diluted. In general, it is pref all customary binders usable in seed dressing products. Pre erable to apply the compositions to the seed in the form of a ferred examples include polyvinylpyrrolidone, polyvinyl suitable formulation. Suitable formulations and methods for acetate, polyvinyl alcohol and tylose. seed treatment are known to those skilled in the art and are 0339. The gibberellins which may be present in the seed described, for example, in the following documents: U.S. Pat. dressing formulations usable in accordance with the inven No. 4,272,417, U.S. Pat. No. 4,245,432, U.S. Pat. No. 4,808, tion may preferably be gibberellins A3 (gibberellic acid), 430, U.S. Pat. No. 5,876,739, US 2003/0176428 A1, WO A4 and A7; particular preference is given to using gibberellic 2002/080675, WO 2002/028.186. acid. The gibberellins are known (cf. R. Wegler “Chemie der 0330. The mixtures or compositions usable in accordance Pflanzenschutz- und Schädlingsbekämpfungsmittel Chem with the invention can be converted to the customary seed istry of the Crop Protection Compositions and Pesticides. dressing formulations, such as Solutions, emulsions, Suspen vol. 2, Springer Verlag, 1970, p. 401-412). US 2015/02824.83 A1 Oct. 8, 2015

0340. The seed dressing formulations usable in accor include adhesives, sizes, paper and card, leather, wood, dance with the invention can be used, either directly or after paints, cooling lubricants and heat transfer fluids, more pref previously having been diluted with water, for the treatment erably wood. of a wide range of different seed, including the seed of trans 0348. The inventive mixtures or compositions may pre genic plants. In this case, additional synergistic effects may vent adverse effects, such as rotting, decay, discoloration, also occur in interaction with the substances formed by decoloration or formation of mould. expression. 0349. In the case of treatment of wood the mixtures or 0341 For treatment of seed with the seed dressing formu compositions according to the invention may also be used lations usable in accordance with the invention, or the prepa against fungal diseases liable to grow on or inside timber. The rations prepared therefrom by adding water, all mixing units term “timber” means all types of species of wood, and all usable customarily for the seed dressing are useful. Specifi types of working of this wood intended for construction, for cally, the procedure in the seed dressing is to place the seed example solid wood, high-density wood, laminated wood, into a mixer, to add the particular desired amount of seed and plywood. The method for treating timber according to the dressing formulations, either as such or after prior dilution invention mainly consists in contacting a mixture or compo with water, and to mix everything until the formulation is sition according to the invention; this includes for example distributed homogeneously on the seed. If appropriate, this is direct application, spraying, dipping, injection or any other followed by a drying process. Suitable means. 0342 Mycotoxins 0350. In addition, the inventive mixtures or compositions 0343. In addition, the inventive treatment can reduce the can be used to protect objects which come into contact with mycotoxin content in the harvested material and the foods and saltwater or brackish water, especially hulls, Screens, nets, feeds prepared therefrom. Mycotoxins include particularly, buildings, moorings and signaling systems, from fouling. but not exclusively, the following: deoxynivalenol (DON). 0351. The inventive method for controlling harmful fungi nivalenol, 15-Ac-DON, 3-Ac-DON, T2- and HT2-toxin, can also be employed for protecting storage goods. Storage fumonisins, Zearalenon, moniliformin, fusarin, diaceotoxy goods are understood to mean natural Substances of vegetable Scirpenol (DAS), beauvericin, enniatin, fusaroproliferin, or animal origin or processed products thereof which are of fusarenol, ochratoxins, patulin, ergot alkaloids and aflatoxins natural origin, and for which long-term protection is desired. which can be produced, for example, by the following fungi. Storage goods of vegetable origin, for example plants or plant Fusarium spec. Such as F. acuminatum, F. asiaticum, F, ave parts, such as stems, leaves, tubers, seeds, fruits, grains, can naceum, F. Crookwellense, F. culmorum, F. graminearum be protected freshly harvested or after processing by (pre) (Gibberella zeae), F equiseti, F. fijikoroi, F musarum, F. drying, moistening, comminuting, grinding, pressing or Oxysporum, F. proliferatum, F. poae, F. pseudograminearum, roasting. Storage goods also include timber, both unproc F. Sambucinum, F. Scirpi, F semitectum, F. Solani, F. Sporot essed. Such as construction timber, electricity poles and bar richoides, F. langsethiae, F subglutinans, F, tricinctum, F. riers, or in the form of finished products, such as furniture. verticillioides etc., and also by Aspergillus spec. Such as A. Storage goods of animal origin are, for example, hides, flavus, A. parasiticus, A. nomius, A. Ochraceus, A. clavatus, A. leather, furs and hairs. The inventive mixtures or composi terreus, A. versicolor, Penicillium spec. Such as P verruco tions may prevent adverse effects, such as rotting, decay, sum, P. viridicatum, P. citrinum, P. expansium, P claviforme, discoloration, decoloration or formation of mould. P roqueforti, Claviceps spec. Such as C. purpurea, C. fitsi 0352 Microorganisms capable of degrading or altering formis, C. paspali, C. africana, Stachybotry's spec. and others. the industrial materials include, for example, bacteria, fungi, yeasts, algae and slime organisms. The inventive mixtures or 0344 Material Protection compositions preferably act against fungi, especially moulds, 0345 The inventive mixtures or compositions or compo wood-discoloring and wood-destroying fungi (Ascomycetes, sitions can also be used in the protection of materials, for Basidiomycetes, Deuteromycetes and Zygomycetes), and protection of industrial materials against attack and destruc against Slime organisms and algae. Examples include micro tion by harmful microorganisms or pests, for example fungi organisms of the following genera: Alternaria, Such as Alter and insects. naria tenuis, Aspergillus, such as Aspergillus niger, Chaeto 0346. In addition, the inventive mixtures or compositions mium, Such as Chaetomium globosum, Coniophora, Such as can be used as antifouling compositions, alone or in combi Coniophora puetana, Lentinus, such as Lentinus tigrinus, nations with other active ingredients. Penicillium, Such as Penicillium glaucum, Polyporus, such as 0347 Industrial materials in the present context are under Polyporus versicolor, Aureobasidium, Such as Aureoba stood to meaninanimate materials which have been prepared sidium pullulans, Sclerophoma, such as Sclerophoma pitvo for use in industry. For example, industrial materials which phila, Trichoderma, such as Trichoderma viride, Ophios are to be protected by inventive mixtures or compositions toma spp., Ceratocystis spp., Humicola spp., Petriella spp., from microbial alteration or destruction may be adhesives, Trichurus spp., Coriolus spp., Gloeophyllum spp., Pleurotus glues, paper, wallpaper and board/cardboard, textiles, car spp., Poria spp., Serpula spp. and Tvromyces spp., Cladospo pets, leather, wood, fibers and tissues, paints and plastic rium spp., Paecilomyces spp. Mucor spp., Escherichia, Such articles, cooling lubricants and other materials which can be as Escherichia coli. Pseudomonas, Such as Pseudomonas infected with or destroyed by microorganisms. Parts of pro aeruginosa, Staphylococcus, such as Staphylococcus aureus, duction plants and buildings, for example cooling-water cir Candida spp. and Saccharomyces spp., Such as Saccharomy cuits, cooling and heating systems and ventilation and air ces cerevisae. conditioning units, which may be impaired by the 0353 Antimycotic Activity proliferation of microorganisms may also be mentioned 0354. In addition, the inventive mixtures or compositions within the scope of the materials to be protected. Industrial also have very good antimycotic activity. They have a very materials within the scope of the present invention preferably broad antimycotic activity spectrum, especially against der US 2015/02824.83 A1 Oct. 8, 2015 36 matophytes and yeasts, moulds and diphasic fungi (for 0360. At certain application rates, the mixtures or compo example against Candida species, such as C. albicans, C. sitions according to the invention may also have a strength glabrata), and Epidermophyton floccosum, Aspergillus spe ening effect in plants. Accordingly, they are also suitable for cies, such as A. niger and A. fumigatus, Trichophyton species, mobilizing the defense system of the plant against attack by Such as T. mentagrophytes, Microsporon species Such as M. harmful microorganisms. This may, if appropriate, be one of canis and M. audouinii. The list of these fungi by no means the reasons of the enhanced activity of the mixtures or com constitutes a restriction of the mycotic spectrum covered, and positions according to the invention, for example against is merely of illustrative character. fungi. Plant-strengthening (resistance-inducing) Substances 0355 The inventive mixtures or compositions can there are to be understood as meaning, in the present context, those fore be used both in medical and in non-medical applications. Substances or combinations of Substances which are capable of stimulating the defense system of plants in Such away that, 0356 Genetically Modified Organisms when Subsequently inoculated with harmful microorganisms, 0357. As already mentioned above, it is possible to treat all the treated plants display a substantial degree of resistance to plants and their parts in accordance with the invention. In a these microorganisms. In the present case, harmful microor preferred embodiment, wild plant species and plant cultivars, ganisms are to be understood as meaning phytopathogenic or those obtained by conventional biological breeding meth fungi, bacteria and viruses. Thus, the mixtures or composi ods, such as crossing or protoplast fusion, and also parts tions according to the invention can be employed for protect thereof, are treated. In a further preferred embodiment, trans ing plants against attack by the abovementioned pathogens genic plants and plant cultivars obtained by genetic engineer within a certain period of time after the treatment. The period ing methods, if appropriate in combination with conventional of time within which protection is effected generally extends methods (Genetically Modified Organisms), and parts from 1 to 10 days, preferably 1 to 7 days, after the treatment thereof are treated. The terms “parts” or “parts of plants’ or of the plants with the active compounds. “plant parts” have been explained above. More preferably, 0361 Plants and plant cultivars which are preferably to be plants of the plant cultivars which are commercially available treated according to the invention include all plants which or are in use are treated in accordance with the invention. have genetic material which impart particularly advanta Plant cultivars are understood to mean plants which have new geous, useful traits to these plants (whether obtained by properties (“traits') and have been obtained by conventional breeding and/or biotechnological means). breeding, by mutagenesis or by recombinant DNA tech 0362 Plants and plant cultivars which are also preferably niques. They can be cultivars, varieties, bio- or genotypes. to be treated according to the invention are resistant against 0358. The method of treatment according to the invention one or more biotic stresses, i.e. said plants show a better can be used in the treatment of genetically modified organ defense against animal and microbial pests, such as against isms (GMOs), e.g. plants or seeds. Genetically modified nematodes, insects, mites, phytopathogenic fungi, bacteria, plants (or transgenic plants) are plants of which a heterolo viruses and/or viroids. gous gene has been stably integrated into genome. The 0363 Examples of nematode or insect resistant plants are expression "heterologous gene' essentially means a gene described in e.g. U.S. patent application Ser. Nos. 1 1/765, which is provided or assembled outside the plant and when 491, 11/765,494, 10/926,819, 10/782,020, 12/032,479, introduced in the nuclear, chloroplastic or mitochondrial 10/783,417, 10/782,096, 11/657,964, 12/192,904, 11/396, genome gives the transformed plant new or improved agro 808, 12/166,253, 12/166,239, 12/166,124, 12/166,209, nomic or other properties by expressing a protein or polypep 11/762,886, 12/364,335, 11/763,947, 12/252,453, 12/209, tide of interest or by downregulating or silencing other gene 354, 12/491,396, 12/497,221, 12/644,632, 12/646,004, (s) which are present in the plant (using for example, 12/701,058, 12/718,059, 12/721,595, 12/638,591. antisense technology, coSuppression technology, RNA inter 0364 Plants and plant cultivars which may also be treated ference-RNAi-technology or microRNA-miRNA-technol according to the invention are those plants which are resistant ogy). A heterologous gene that is located in the genome is also to one or more abiotic stresses. Abiotic stress conditions may called a transgene. A transgene that is defined by its particular include, for example, drought, cold temperature exposure, location in the plant genome is called a transformation or heat exposure, osmotic stress, flooding, increased soil salin transgenic event. ity, increased mineral exposure, oZone exposure, high light 0359. Depending on the plant species or plant cultivars, exposure, limited availability of nitrogen nutrients, limited their location and growth conditions (soils, climate, vegeta availability of phosphorus nutrients, shade avoidance. tion period, diet), the treatment according to the invention 0365 Plants and plant cultivars which may also be treated may also result in superadditive (“synergistic) effects. Thus, according to the invention, are those plants characterized by for example, reduced application rates and/or a widening of enhanced yield characteristics. Increased yield in said plants the activity spectrum and/or an increase in the activity of the can be the result of for example, improved plant physiology, active compounds and compositions which can be used growth and development, such as water use efficiency, water according to the invention, better plant growth, increased retention efficiency, improved nitrogen use, enhanced carbon tolerance to high or low temperatures, increased tolerance to assimilation, improved photosynthesis, increased germina drought or to water or soil salt content, increased flowering tion efficiency and accelerated maturation. Yield can further performance, easier harvesting, accelerated maturation, more be affected by improved plantarchitecture (under stress higher harvest yields, bigger fruits, larger plant height, and non-stress conditions), including but not limited to, early greener leaf color, earlier flowering, higher quality and/or a flowering, flowering control for hybrid seed production, seed higher nutritional value of the harvested products, higher ling vigor, plant size, internode number and distance, root Sugar concentration within the fruits, better storage stability growth, seed size, fruit size, pod size, pod or ear number, seed and/or processability of the harvested products are possible, number per pod or ear, seed mass, enhanced seed filling, which exceed the effects which were actually to be expected. reduced seed dispersal, reduced pod dehiscence and lodging US 2015/02824.83 A1 Oct. 8, 2015 37 resistance. Further yield traits include seed composition, Such glyphosate acetyl transferase enzyme as described in for as carbohydrate content, protein content, oil content and com example WO 02/036782, WO 03/092360, WO 2005/012515 position, nutritional value, reduction in anti-nutritional com and WO 2007/024782. Glyphosate-tolerant plants can also be pounds, improved processability and better storage stability. obtained by selecting plants containing naturally-occurring 0366 Plants that may be treated according to the invention mutations of the above-mentioned genes, as described in for are hybrid plants that already express the characteristic of example WO 01/024615 or WO 03/013226. Plants express heterosis or hybrid vigor which results in generally higher ing EPSPS genes that confer glyphosate tolerance are yield, vigor, health and resistance towards biotic and abiotic described in e.g. U.S. patent application Ser. Nos. 11/517, stresses). Such plants are typically made by crossing an 991, 10/739,610, 12/139,408, 12/352,532, 11/312,866, inbred male-sterile parent line (the female parent) with 11/315,678, 12/421,292, 11/400,598, 11/651,752, 11/681, another inbred male-fertile parent line (the male parent). 285, 11/605,824, 12/468,205, 11/760,570, 11/762,526, Hybrid seed is typically harvested from the malesterile plants 11/769,327, 11/769,255, 11/943801 or 12/362,774. Plants and sold to growers. Malesterile plants can sometimes (e.g. in comprising other genes that confer glyphosate tolerance, corn) be produced by detasseling, i.e. the mechanical removal Such as decarboxylase genes, are described in e.g. U.S. patent of the male reproductive organs (or males flowers) but, more application Ser. Nos. 1 1/588,811, 11/185.342, 12/364,724, typically, malesterility is the result of genetic determinants in 11/185,560 or 12/423,926. the plant genome. In that case, and especially when seed is the 0369. Other herbicide resistant plants are for example desired product to be harvested from the hybrid plants it is plants that are made tolerant to herbicides inhibiting the typically useful to ensure that male fertility in the hybrid enzyme glutamine synthase. Such as bialaphos, phosphino plants is fully restored. This can be accomplished by ensuring thricin or glufosinate. Such plants can be obtained by express that the male parents have appropriate fertility restorer genes ing an enzyme detoxifying the herbicide or a mutant which are capable of restoring the male fertility in hybrid glutamine synthase enzyme that is resistant to inhibition, e.g. plants that contain the genetic determinants responsible for described in U.S. patent application Ser. No. 1 1/760,602. One male-sterility. Genetic determinants for malesterility may be Such efficient detoxifying enzyme is an enzyme encoding a located in the cytoplasm. Examples of cytoplasmic male Ste phosphinothricin acetyltransferase (such as the bar or pat rility (CMS) were for instance described in Brassica species protein from Streptomyces species). Plants expressing an (WO 92/05251, WO 95/09910, WO 98/27806, WO exogenous phosphinothricin acetyltransferase are for 05/002324, WO 06/021972 and U.S. Pat. No. 6,229,072). example described in U.S. Pat. Nos. 5,561.236; 5,648,477: However, genetic determinants for male sterility can also be 5,646,024: 5,273,894; 5,637,489: 5,276.268; 5,739,082: located in the nuclear genome. Malesterile plants can also be 5,908,810 and 7,112,665. obtained by plant biotechnology methods such as genetic 0370 Further herbicide-tolerant plants are also plants that engineering. A particularly useful means of obtaining male are made tolerant to the herbicides inhibiting the enzyme sterile plants is described in WO 89/10396 in which, for hydroxyphenylpyruvatedioxygenase (HPPD). HPPD is an example, a ribonuclease Such as barnase is selectively enzyme that catalyze the reaction in which parahydroxyphe expressed in the tapetum cells in the stamens. Fertility can nylpyruvate (HPP) is transformed into homogentisate. Plants then be restored by expression in the tapetum cells of a ribo tolerant to HPPD-inhibitors can be transformed with a gene nuclease inhibitor such as barstar (e.g. WO91/02069). encoding a naturally-occurring resistant HPPD enzyme, or a 0367 Plants or plant cultivars (obtained by plant biotech gene encoding a mutated or chimeric HPPD enzyme as nology methods such as genetic engineering) which may be described in WO 96/38567, WO 99/24585, WO 99/24586, treated according to the invention are herbicide-tolerant WO 09/144079, WO 02/046387, or U.S. Pat. No. 6,768,044. plants, i.e. plants made tolerant to one or more given herbi Tolerance to HPPD-inhibitors can also be obtained by trans cides. Such plants can be obtained either by genetic transfor forming plants with genes encoding certain enzymes mation, or by selection of plants containing a mutation enabling the formation of homogentisate despite the inhibi imparting Such herbicide tolerance. tion of the native HPPD enzyme by the HPPD-inhibitor. Such 0368 Herbicide-resistant plants are for example glypho plants and genes are described in WO 99/34008 and WO sate-tolerant plants, i.e. plants made tolerant to the herbicide 02/36787. Tolerance of plants to HPPD inhibitors can also be glyphosate or salts thereof. Plants can be made tolerant to improved by transforming plants with a gene encoding an glyphosate through different means. For example, glypho enzyme having prephenate deshydrogenase (PDH) activity in sate-tolerant plants can be obtained by transforming the plant addition to a gene encoding an HPPD-tolerant enzyme, as with a gene encoding the enzyme 5-enolpyruvylshikimate-3- described in WO 04/024928. Further, plants can be made phosphate synthase (EPSPS). Examples of such EPSPS more tolerant to HPPD-inhibitor herbicides by adding into genes are the AroA gene (mutant CT7) of the bacterium their genome a gene encoding an enzyme capable of metabo Salmonella typhimurium (Science 1983, 221, 370-371), the lizing or degrading HPPD inhibitors, such as the CYP450 CP4 gene of the bacterium Agrobacterium sp. (Curr. Topics enzymes shown in WO 2007/103567 and WO 2008/150473. Plant Physiol. 1992, 7, 139-145), the genes encoding a Petu 0371. Still further herbicide resistant plants are plants that nia EPSPS (Science 1986,233,478-481), a Tomato EPSPS (J. are made tolerant to acetolactate synthase (ALS) inhibitors. Biol. Chem. 1988, 263, 4280-4289), or an Eleusine EPSPS 0372 Known ALS-inhibitors include, for example, sulfo (WO 01/66704). It can also be a mutated EPSPS as described nylurea, imidazolinone, triazolopyrimidines, pryimidinyoxy in for example EP 0837944, WO 00/66746, WO 00/66747 or (thio)benzoates, and/or Sulfonylaminocarbonyltriazolinone WO 02/26995. Glyphosate-tolerant plants can also be herbicides. Different mutations in the ALS enzyme (also obtained by expressing a gene that encodes a glyphosate known as acetohydroxyacid synthase, AHAS) are known to oxido-reductase enzyme as described in U.S. Pat. No. 5,776, confer tolerance to different herbicides and groups of herbi 760 and U.S. Pat. No. 5,463,175. Glyphosate-tolerant plants cides, as described for example in Tranel and Wright (Weed can also be obtained by expressing a gene that encodes a Science 2002, 50,700-712), but also, in U.S. Pat. Nos. 5,605, US 2015/02824.83 A1 Oct. 8, 2015

011, 5,378,824, 5,141,870, and 5,013,659. The production of or a hybrid of the proteins of 2) above, e.g., the Cry1A. Sulfonylurea-tolerant plants and imidazolinone-tolerant 105 protein produced by corn event MON89034 (WO plants is described in U.S. Pat. Nos. 5,605,011; 5,013,659; 2007/027777); or 5,141,870; 5,767,361; 5,731, 180; 5,304,732; 4,761,373; 0380 4) a protein of any one of 1) to 3) above wherein 5,331,107; 5,928,937; and 5,378,824; and WO 96/33270. Some, particularly 1 to 10, amino acids have been Other imidazolinone-tolerant plants are also described in for replaced by anotheramino acid to obtain a higher insec example WO 2004/040012, WO 2004/106529, WO 2005/ ticidal activity to a targetinsect species, and/or to expand 020673, WO 2005/093093, WO 2006/007373, WO 2006/ the range of target insect species affected, and/or O15376, WO 2006/024351, and WO 2006/060634. Further because of changes introduced into the encoding DNA Sulfonylurea- and imidazolinone-tolerant plants are also during cloning or transformation, such as the Cry3Bb1 described in for example WO 2007/024782 and U.S. Patent protein in corn events MON863 or MON88017, or the Application 61/288,958. Cry3A protein in corn event MIR604; or 0373) Other plants tolerant to imidazolinone and/or sulfo 0381 5) an insecticidal secreted protein from Bacillus nylurea can be obtained by induced mutagenesis, selection in thuringiensis or Bacillus cereus, or an insecticidal por cell cultures in the presence of the herbicide or mutation tion thereof, such as the vegetative insecticidal (VIP) breeding as described for example for soybeans in U.S. Pat. proteins listed at: No. 5,084,082, for rice in WO 97/41218, for sugar beet in 0382 http://www.lifesci.sussex.ac.uk/home/Neil U.S. Pat. No. 5,773,702 and WO 99/057965, for lettuce in Crickmore/Bt/vip.html, e.g., proteins from the U.S. Pat. No. 5,198,599, or for sunflower in WO 01/065922. VIP3Aa protein class; or 0374. Other plants tolerant to imidazolinone and/or sulfo 0383 6) a secreted protein from Bacillus thuringiensis nylurea can be obtained by induced mutagenesis, selection in or Bacillus cereus which is insecticidal in the presence cell cultures in the presence of the herbicide or mutation of a second secreted protein from Bacillus thuringiensis breeding as described for example for soybeans in U.S. Pat. or B. cereus, such as the binary toxin made up of the No. 5,084,082, for rice in WO 97/41218, for sugar beet in VIP1A and VIP2A proteins (WO 94/21795); or U.S. Pat. No. 5,773,702 and WO 99/057965, for lettuce in 0384 7) a hybrid insecticidal protein comprising parts U.S. Pat. No. 5,198,599, or for sunflower in WO 01/065922. from different secreted proteins from Bacillus thuring 0375 Plants or plant cultivars (obtained by plant biotech iensis or Bacillus cereus, such as a hybrid of the proteins nology methods such as genetic engineering) which may also in 1) above or a hybrid of the proteins in 2) above; or be treated according to the invention are insect-resistant 0385) 8) a protein of any one of 5) to 7) above wherein transgenic plants, i.e. plants made resistant to attack by cer Some, particularly 1 to 10, amino acids have been tain target insects. Such plants can be obtained by genetic replaced by anotheramino acid to obtain a higher insec transformation, or by selection of plants containing a muta ticidal activity to a targetinsect species, and/or to expand tion imparting Such insect resistance. the range of target insect species affected, and/or 0376 An “insect-resistant transgenic plant, as used because of changes introduced into the encoding DNA herein, includes any plant containing at least one transgene during cloning or transformation (while still encoding comprising a coding sequence encoding: an insecticidal protein), such as the VIP3Aa protein in cotton event COT 102; or 0377 1) an insecticidal crystal protein from Bacillus 0386 9) a secreted protein from Bacillus thuringiensis thuringiensis or an insecticidal portion thereof. Such as or Bacillus cereus which is insecticidal in the presence the insecticidal crystal proteins listed by Crickmore et al. of a crystal protein from Bacillus thuringiensis, such as (1998, Microbiology and Molecular Biology Reviews, the binary toxin made up of VIP3 and Cry1A or Cry 1F 62:807-813), updated by Crickmore et al. (2005) at the (U.S. Patent Applications 61/126,083 and 61/195,019), Bacillus thuringiensis toxin nomenclature, online at: or the binary toxin made up of the VIP3 protein and the http://www.lifesci.sussex.ac.uk/Home/Neil Crick Cry2Aa or Cry2Ab or Cry2Ae proteins (U.S. patent more/Bt/), or insecticidal portions thereof, e.g., proteins application Ser. No. 12/214,022 and EP-A 2300 618). of the Cry protein classes Cry1Ab, Cry1Ac, Cry 1B, 0387 10) a protein of 9) above wherein some, particu Cry1C, Cry 1D, Cry1F, Cry2Ab, Cry3Aa, or Cry3Bb or larly 1 to 10, amino acids have been replaced by another insecticidal portions thereof (e.g. EP-A 1999 141 and amino acid to obtain a higher insecticidal activity to a WO 2007/107302), or such proteins encoded by syn target insect species, and/or to expand the range of target thetic genes as e.g. described in and U.S. patent appli insect species affected, and/or because of changes intro cation Ser. No. 12/249,016; or duced into the encoding DNA during cloning or trans 0378. 2) a crystal protein from Bacillus thuringiensis or formation (while still encoding an insecticidal protein) a portion thereof which is insecticidal in the presence of 0388 Of course, an insect-resistant transgenic plant, as a second other crystal protein from Bacillus thuringien used herein, also includes any plant comprising a combina sis or a portion thereof. Such as the binary toxin made up tion of genes encoding the proteins of any one of the above of the Cry34 and Cry35 crystal proteins (Nat. Biotech classes 1 to 10. In one embodiment, an insect-resistant plant mol. 2001, 19, 668-72; Applied Environm. Microbiol. contains more than one transgene encoding a protein of any 2006, 71, 1765-1774) or the binary toxin made up of the one of the above classes 1 to 10, to expand the range of target Cry1A or Cry1F proteins and the Cry2Aa or Cry2Ab or insect species affected when using different proteins directed Cry2Ae proteins (U.S. patent application Ser. No. at different target insect species, or to delay insect resistance 12/214,022 and EP-A 2300 618); or development to the plants by using different proteins insecti 0379 3) a hybrid insecticidal protein comprising parts cidal to the same target insect species but having a different of different insecticidal crystal proteins from Bacillus mode of action, such as binding to different receptor binding thuringiensis, such as a hybrid of the proteins of 1) above sites in the insect. US 2015/02824.83 A1 Oct. 8, 2015 39

0389. An “insect-resistant transgenic plant, as used 2008/090008, WO 01/14569, WO 02/79410, WO herein, further includes any plant containing at least one 03/33540, WO 2004/078983, WO 01/19975, WO transgene comprising a sequence producing upon expression 95/26407, WO 96/34968, WO 98/20145, WO 99/12950, a double-stranded RNA which upon ingestion by a plant WO99/66050, WO 99/53072, U.S. Pat. No. 6,734,341, insect pest inhibits the growth of this insect pest, as described WO 00/11192, WO 98/22604, WO 98/32326, WO e.g. in WO 2007/080126, WO 2006/129204, WO 2007/ 01/98509, WO 01/98509, WO 2005/002359, U.S. Pat. 074405, WO 2007/080127 and WO 2007/035650. No. 5,824,790, U.S. Pat. No. 6,013,861, WO 94/04693, 0390 Plants or plant cultivars (obtained by plant biotech WO 94/09144, WO 94/11520, WO 95/35026, WO nology methods such as genetic engineering) which may also 97/20936, WO 2010/012796, WO 2010/003701, be treated according to the invention are tolerant to abiotic 0396 2) transgenic plants which synthesize non starch stresses. Such plants can be obtained by genetic transforma carbohydrate polymers or which synthesize non starch tion, or by selection of plants containing a mutation imparting carbohydrate polymers with altered properties in com Such stress resistance. Particularly useful stress tolerance parison to wildtype plants without genetic modification. plants include: Examples are plants producing polyfructose, especially 0391 1) plants which contain a transgene capable of of the inulin and levan-type, as disclosed in EP-AO 663 reducing the expression and/or the activity of poly 956, WO 96/01904, WO 96/21023, WO 98/39460, and (ADP-ribose) polymerase (PARP) gene in the plant cells WO 99/24593, plants producing alpha-1,4-glucans as or plants as described in WO 00/04173, WO 2006/ disclosed in WO95/31553, US 2002031826, U.S. Pat. 045633, EP-A 1807 519, or EP-A 2018 431. No. 6,284,479, U.S. Pat. No. 5,712,107, WO 97/47806, 0392 2) plants which contain a stress tolerance enhanc WO 97/47807, WO 97/47808 and WO 00/14249, plants ing transgene capable of reducing the expression and/or producing alpha-1,6 branched alpha-1,4-glucans, as dis the activity of the PARG encoding genes of the plants or closed in WO 00/73422, plants producing alternan, as plants cells, as described e.g. in WO 2004/090140. disclosed in e.g. WO 00/47727, WO 00/73422, EP 0393 3) plants which contain a stress tolerance enhanc 06077301.7, U.S. Pat. No. 5,908,975 and EP-A 0728 ing transgene coding for a plant-functional enzyme of 213, the nicotineamide adenine dinucleotide salvage synthe 0397 3) transgenic plants which produce hyaluronan, sis pathway including nicotinamidase, nicotinate phos as for example disclosed in WO 2006/032538, WO phoribosyltransferase, nicotinic acid mononucleotide 2007/039314, WO 2007/039315, WO 2007/039316, adenyl transferase, nicotinamide adenine dinucleotide JP-A 2006-304779, and WO 2005/012529. synthetase or nicotine amide phosphorybosyltransferase 0398. 4) transgenic plants or hybrid plants, such as as described e.g. in EP-A 1794306, WO 2006/133827, onions with characteristics Such as high soluble Solids WO 2007/107326, EP-A 1999 263, or WO 2007/ content, low pungency (LP) and/or long storage 107326. (LS), as described in U.S. patent application Ser. Nos. 0394 Plants or plant cultivars (obtained by plant biotech 12/020,360 and 61/054,026. nology methods such as genetic engineering) which may also 0399 Plants or plant cultivars (that can be obtained by be treated according to the invention show altered quantity, plant biotechnology methods such as genetic engineering) quality and/or storage-stability of the harvested product and/ which may also be treated according to the invention are or altered properties of specific ingredients of the harvested plants, such as cotton plants, with altered fiber characteristics. product Such as: Such plants can be obtained by genetic transformation, or by 0395. 1) transgenic plants which synthesize a modified selection of plants contain a mutation imparting Such altered starch, which in its physical-chemical characteristics, in fiber characteristics and include: particular the amylose content or the amylose/amy 04.00 a) Plants, such as cotton plants, containing an lopectin ratio, the degree of branching, the average chain altered form of cellulose synthase genes as described in length, the side chain distribution, the viscosity behav WO 98/OO549. iour, the gelling strength, the starch grain size and/or the 04.01 b) Plants, such as cotton plants, containing an starch grain morphology, is changed in comparison with altered form of rSw2 or rSw3 homologous nucleic acids the synthesised Starch in wild type plant cells or plants, as described in WO 2004/053219. so that this is better suited for special applications. Said 0402 c) Plants, such as cotton plants, with increased transgenic plants synthesizing a modified starch are dis expression of Sucrose phosphate synthase as described closed, for example, in EP-A 0571427, WO95/04826, in WOO1f17333. EP-A 0 719 338, WO 96/15248, WO 96/19581, WO 96/27674, WO 97/11188, WO 97/26362, WO 97/32985, 0403 d) Plants, such as cotton plants, with increased WO 97/42328, WO 97/44472, WO 97/45545, WO expression of sucrose synthase as described in WO 98/27212, WO 98/40503, WO99/58688, WO99/58690, O2/45485. WO 99/58654, WO 00/08184, WO 00/08185, WO 0404 e) Plants, such as cotton plants, wherein the tim 00/08175, WO 00/28052, WO 00/77229, WO 01/12782, ing of the plasmodesmatal gating at the basis of the fiber WO 01/12826, WO 02/101059, WO 03/071860, WO cell is altered, e.g. through downregulation of fiber 04/056999, WO 05/030942, WO 2005/030941, WO selective B-1,3-glucanase as described in WO 2005/ 2005/095632, WO 2005/095617, WO 2005/095619, 017157, or as described in WO 2009/143995. WO 2005/095618, WO 2005/123927, WO 2006/ 04.05 f) Plants, such as cotton plants, having fibers with 0183.19, WO 2006/103107, WO 2006/108702, WO altered reactivity, e.g. through the expression of 2007/009823, WO 00/22140, WO 2006/063862, WO N-acetylglucosaminetransferase gene including nodC 2006/072603, WO 02/034923, WO 2008/017518, WO and chitin synthase genes as described in WO 2006/ 2008/080630, WO 2008/080631, EP 07090007.1, WO 136351. US 2015/02824.83 A1 Oct. 8, 2015 40

0406 Plants or plant cultivars (that can be obtained by 0418 Transformation event or line: the name of the plant biotechnology methods such as genetic engineering) event or events (sometimes also designated as lines or which may also be treated according to the invention are lines) for which nonregulated Status is requested. plants, such as oilseed rape or related Brassica plants, with 0419 APHIS documents: various documents published altered oil profile characteristics. Such plants can be obtained by APHIS in relation to the Petition and which can be by genetic transformation, or by selection of plants contain a requested with APHIS. mutation imparting such altered oil profile characteristics and 0420 Additional particularly useful plants containing include: single transformation events or combinations of transforma 0407 a) Plants, such as oilseed rape plants, producing tion events are listed for example in the databases from vari oil having a high oleic acid content as described e.g. in ous national or regional regulatory agencies (see for example U.S. Pat. No. 5,969,169, U.S. Pat. No. 5,840,946 or U.S. http://gmoinfo.jrc.it/gmp browse.aspx and http://www.ag Pat. No. 6,323,392 or U.S. Pat. No. 6,063,947 bios.com/dbase.php). 0408 b) Plants such as oilseed rape plants, producing 0421 Particularly useful transgenic plants which may be oil having a low linolenic acid content as described in treated according to the invention are plants containing trans U.S. Pat. No. 6,270,828, U.S. Pat. No. 6,169,190, or U.S. formation events, or a combination of transformation events, Pat. No. 5,965,755 and that are listed for example in the databases for various 04.09 c) Plant such as oilseed rape plants, producing oil national or regional regulatory agencies including Event having a low level of saturated fatty acids as described 1143-14A (cotton, insect control, not deposited, described in e.g. in U.S. Pat. No. 5,434.283 or U.S. patent application WO 2006/128569); Event 1143-51B (cotton, insect control, Ser. No. 12/668,303 not deposited, described in WO 2006/128570); Event 1445 0410 Plants or plant cultivars (that can be obtained by (cotton, herbicide tolerance, not deposited, described in plant biotechnology methods such as genetic engineering) US-A 2002-120964 or WO 02/034946); Event 17053 (rice, which may also be treated according to the invention are herbicide tolerance, deposited as PTA-9843, described in WO plants, such as oilseed rape or related Brassica plants, with 2010/117737); Event 17314 (rice, herbicide tolerance, depos altered seed shattering characteristics. Such plants can be ited as PTA-9844, described in WO 2010/117735): Event obtained by genetic transformation, or by selection of plants 281-24-236 (cotton, insect control herbicide tolerance, contain a mutation imparting such altered seed shattering deposited as PTA-6233, described in WO 2005/103266 or characteristics and include plants such as oilseed rape plants US-A 2005-216969): Event 3006-210-23 (cotton, insect con with delayed or reduced seed shattering as described in U.S. trol herbicide tolerance, deposited as PTA-6233, described Patent Application 61/135,230, WO 2009/068313 and WO in US-A 2007-143876 or WO 2005/103266): Event 3272 201O/OO6732 (corn, quality trait, deposited as PTA-9972, described in WO 0411 Plants or plant cultivars (that can be obtained by 2006/098952 or US-A 2006-230473); Event 40416 (corn, plant biotechnology methods such as genetic engineering) insect control herbicide tolerance, deposited as ATCCPTA which may also be treated according to the invention are 11508, described in WO 2011/075593); Event 43A47 (corn, plants, such as Tobacco plants, with altered posttranslational insect control herbicide tolerance, deposited as ATCCPTA protein modification patterns, for example as described in 11509, described in WO 2011/075595): Event 5307 (corn, WO 201Of 121818 and WO 2010/145846. insect control, deposited as ATCC PTA-9561, described in 0412 Particularly useful transgenic plants which may be WO 2010/077816); Event ASR-368 (bent grass, herbicide treated according to the invention are plants containing trans tolerance, deposited as ATCC PTA-4816, described in US-A formation events, or combination of transformation events, 2006-162007 or WO 2004/053062): Event B16 (corn, herbi that are the Subject of petitions for non-regulated Status, in the cide tolerance, not deposited, described in US-A 2003 United States of America, to the Animal and Plant Health 126634); Event BPS-CV127-9 (soybean, herbicide tolerance, Inspection Service (APHIS) of the United States Department deposited as NCIMB No. 41603, described in WO 2010/ of Agriculture (USDA) whether such petitions are granted or 080829): Event CE43-67B (cotton, insect control, deposited are still pending. At any time this information is readily avail as DSM ACC2724, described in US-A 2009-217423 or able from APHIS (4700 River Road, Riverdale, Md. 20737, WO2006/128573); Event CF44-69D (cotton, insect control, USA), for instance on its internet site (URL http://www. not deposited, described in US-A 2010-0024077); Event aphis.usda.gov/brS/not reg.html). On the filing date of this CF44-69D (cotton, insect control, not deposited, described in application the petitions for nonregulated Status that were WO 2006/128571): Event CF46-02A (cotton, insect control, pending with APHIS or granted by APHIS were those which not deposited, described in WO 2006/128572); Event contains the following information: COT 102 (cotton, insect control, not deposited, described in 0413 Petition: the identification number of the petition. US-A 2006-130175 or WO 2004/039986); Event COT202 Technical descriptions of the transformation events can (cotton, insect control, not deposited, described in US-A be found in the individual petition documents which are 2007-067868 or WO 2005/054479): Event COT203 (cotton, obtainable from APHIS, for example on the APHIS web insect control, not deposited, described in WO 2005/054480); site, by reference to this petition number. These descrip Event DAS40278 (corn, herbicide tolerance, deposited as tions are herein incorporated by reference. ATCC PTA-10244, described in WO 2011/022469): Event 0414 Extension of Petition: reference to a previous DAS-59122-7 (corn, insect control herbicide tolerance, petition for which an extension is requested. deposited as ATCC PTA 11384, described in US-A 2006 0415. Institution: the name of the entity submitting the 070139): Event DAS-59132 (corn, insect control herbicide petition. tolerance, not deposited, described in WO 2009/100188): 0416 Regulated article: the plant species concerned. Event DAS68416 (soybean, herbicide tolerance, deposited as 0417 Transgenic phenotype: the trait conferred to the ATCC PTA-10442, described in WO 2011/066384 or WO plants by the transformation event. 2011/066360): Event DP-098140-6 (corn, herbicide toler US 2015/02824.83 A1 Oct. 8, 2015

ance, deposited as ATCC PTA-8296, described in US-A MON87769 (soybean, quality trait, deposited as ATCC PTA 2009-137395 or WO 2008/112019); Event DP-305423-1 8911, described in US-A 2011-0067141 or WO 2009/ (Soybean, quality trait, not deposited, described in US-A 102873); Event MON88017 (corn, insect control herbicide 2008-312082 or WO 2008/054747); Event DP-32138-1 tolerance, deposited as ATCC PTA-5582, described in US-A (corn, hybridization system, deposited as ATCC PTA-9158, 2008-0284.82 or WO 2005/059103): Event MON88913 (cot described in US-A 2009-0210970 or WO 2009/103049): ton, herbicide tolerance, deposited as ATCC PTA-4854. Event DP-356043-5 (soybean, herbicide tolerance, deposited described in WO 2004/072235 or US-A2006-059590); Event as ATCC PTA-8287, described in US-A 2010-0184079 or MON89034 (corn, insect control, deposited as ATCC PTA WO 2008/002872); Event EE-1 (brinjal, insect control, not 7455, described in WO 2007/140256 or US-A 2008-260932); deposited, described in WO 2007/091277); Event FI117 Event MON89788 (soybean, herbicide tolerance, deposited (corn, herbicide tolerance, deposited as ATCC 209031, as ATCC PTA-6708, described in US-A 2006-282915 or WO described in US-A 2006-059581 or WO98/044140); Event 2006/130436): Event MS 11 (oilseed rape, pollination con GA21 (corn, herbicide tolerance, deposited as ATCC 209033, trol herbicide tolerance, deposited as ATCC PTA-850 or described in US-A 2005-086719 or WO98/044140); Event PTA-2485, described in WO 01/031042); Event MS8 (oilseed GG25 (corn, herbicide tolerance, deposited as ATCC 209032, rape, pollination control herbicide tolerance, deposited as described in US-A 2005-188434 or WO 98/044140); Event ATCC PTA-730, described in WO 01/041558 or US-A 2003 GHB 119 (cotton, insect control herbicide tolerance, depos 188347); Event NK603 (corn, herbicide tolerance, deposited ited as ATCC PTA-8398, described in WO 2008/151780); as ATCCPTA-2478, described in US-A2007-292854); Event Event GHB614 (cotton, herbicide tolerance, deposited as PE-7 (rice, insect control, not deposited, described in WO ATCC PTA-6878, described in US-A 2010-050282 or WO 2008/114282): Event RF3 (oilseed rape, pollination con 2007/017186); Event GJ11 (corn, herbicide tolerance, depos trol herbicide tolerance, deposited as ATCC PTA-730, ited as ATCC 209030, described in US-A 2005-188434 or described in WO 01/041558 or US-A 2003-188347); Event WO 98/044140); Event GM RZ13 (sugar beet, virus resis RT73 (oilseed rape, herbicide tolerance, not deposited, tance, deposited as NCIMB-41601, described in WO 2010/ described in WO 02/036831 or US-A 2008-070260); Event 076212); Event H7-1 (sugar beet, herbicide tolerance, depos T227-1 (sugar beet, herbicide tolerance, not deposited, ited as NCIMB 41158 or NCIMB 41159, described in US-A described in WO 02/44407 or US-A 2009-265817); Event 2004-172669 or WO 2004/074492); Event JOPLIN1 (wheat, T25 (corn, herbicide tolerance, not deposited, described in disease tolerance, not deposited, described in US-A 2008 US-A 2001-029014 or WO 01/051654); Event T304-40 (cot 0.64032): Event LL27 (soybean, herbicide tolerance, depos ton, insect control herbicide tolerance, deposited as ATCC ited as NCIMB41658, described in WO 2006/108674 or PTA-8171, described in US-A 2010-077501 or WO 2008/ US-A 2008-320616); Event LL55 (soybean, herbicide toler 122406); Event T342-142 (cotton, insect control, not depos ance, deposited as NCIMB 41660, described in WO 2006/ ited, described in WO 2006/128568); Event TC1507 (corn, 108675 or US-A 2008-196127); Event LLcotton25 (cotton, insect control—herbicide tolerance, not deposited, described herbicide tolerance, deposited as ATCCPTA-3343, described in US-A 2005-039226 or WO 2004/099447); Event VIP1034 in WO 03/013224 or US-A 2003-097687); Event LLRICE06 (corn, insect control—herbicide tolerance, deposited as (rice, herbicide tolerance, deposited as ATCC-23352, ATCC PTA-3925., described in WO 03/052073), Event described in U.S. Pat. No. 6,468,747 or WO 00/026345); 32316 (corn, insect control herbicide tolerance, eposited as Event LLRICE601 (rice, herbicide tolerance, deposited as PTA-11507, described in WO 2011/084632), Event 4114 ATCC PTA-2600, described in US-A 2008-2289060 or WO (corn, insect control herbicide tolerance, deposited as PTA 00/026356); Event LYO38 (corn, quality trait, deposited as 11506, described in WO 2011/084621). ATCC PTA-5623, described in US-A 2007-028322 or WO 0422 Very particularly useful transgenic plants which 2005/061720): Event MIR162 (corn, insect control, depos may be treated according to the invention are plants contain ited as PTA-8166, described in US-A 2009-300784 or WO ing transformation events, or a combination of transformation 2007/142840); Event MIR604 (corn, insect control, not events, and that are listed for example in the databases for deposited, described in US-A 2008-167456 or WO 2005/ various national or regional regulatory agencies including 103301); Event MON15985 (cotton, insect control, deposited Event BPS-CV127-9 (soybean, herbicide tolerance, depos as ATCC PTA-2516, described in US-A 2004-250317 or WO ited as NCIMB No. 41603, described in WO 2010/080829); 02/100163): Event MON810 (corn, insect control, not depos Event DAS68416 (soybean, herbicide tolerance, deposited as ited, described in US-A 2002-102582): Event MON863 ATCC PTA-10442, described in WO 2011/066384 or WO (corn, insect control, deposited as ATCC PTA-2605, 2011/066360): Event DP-356043-5 (soybean, herbicide tol described in WO 2004/011601 or US-A2006-095986); Event erance, deposited as ATCC PTA-8287, described in US-A MON87427 (corn, pollination control, deposited as ATCC 2010-0184079 or WO 2008/002872); Event EE-1 (brinjal, PTA-7899, described in WO 2011/062904); Event insect control, not deposited, described in WO 2007/091277); MON87460 (corn, stress tolerance, deposited as ATCC PTA Event FI117 (corn, herbicide tolerance, deposited as ATCC 8910, described in WO 2009/11 1263 or US-A 2011 209031, described in US-A2006-059581 or WO98/044140); 0138504); Event MON87701 (soybean, insect control, Event GA21 (corn, herbicide tolerance, deposited as ATCC deposited as ATCC PTA-8194, described in US-A 2009 209033, described in US-A 2005-086719 or WO98/044140), 130071 or WO 2009/064652); Event MON87705 (soybean, Event LL27 (soybean, herbicide tolerance, deposited as quality trait herbicide tolerance, deposited as ATCC PTA NCIMB41658, described in WO 2006/108674 or US-A 9241, described in US-A 2010-0080887 or WO 2010/ 2008-320616); Event LL55 (soybean, herbicide tolerance, 037016); Event MON87708 (soybean, herbicide tolerance, deposited as NCIMB 41660, described in WO 2006/108675 deposited as ATCC PTA9670, described in WO 2011/ or US-A 2008-196127); Event MON87701 (soybean, insect 034704); Event MON87754 (soybean, quality trait, deposited control, deposited as ATCC PTA-8194, described in US-A as ATCC PTA-9385, described in WO 2010/024976); Event 2009-130071 or WO 2009/064652); Event MON87705 (soy US 2015/02824.83 A1 Oct. 8, 2015 42 bean, quality trait herbicide tolerance, deposited as ATCC and antagonistic responses of herbicide combinations' PTA-9241, described in US-A 2010-0080887 or WO 2010/ Weeds, (1967), 15, pages 20-22. 037016); Event MON87708 (soybean, herbicide tolerance, 0433. The latter article mentions the formula: deposited as ATCC PTA9670, described in WO 2011/ 034704); Event MON87754 (soybean, quality trait, deposited as ATCC PTA-9385, described in WO 2010/024976); Event E = x + y - MON87769 (soybean, quality trait, deposited as ATCC PTA X -- Y - 100 8911, described in US-A 2011-0067141 or WO 2009/ 102873); Event MON89788 (soybean, herbicide tolerance, 0434 wherein E represents the expected percentage of deposited as ATCC PTA-6708, described in US-A 2006 inhibition of the pest for the combination of the two com 282915 or WO 2006/130436). pounds at defined doses (for example equal to Xandy respec 0423 Application Rates and Timing tively), X is the percentage of inhibition observed for the pest by compound (A) at a defined dose (equal to X), Y is the 0424. When using the inventive mixtures or compositions percentage of inhibition observed for the pest by compound as fungicides, the application rates can be varied within a (B) at a defined dose (equal to y). When the percentage of relatively wide range, depending on the kind of application. inhibition observed for the combination is greater than E, The application rate of the mixtures or compositions is there is a synergistic effect. 0425 in the case of treatment of plant parts, for example 0435 The term “synergistic effect” also means the effect leaves: from 0.1 to 10 000 g/ha, preferably from 10 to defined by application of the Tammes method, “Isoboles, a 1000 g/ha, more preferably from 10 to 800 g/ha, even graphic representation of synergism in pesticides, Nether more preferably from 50 to 300 g/ha (in the case of lands Journal of Plant Pathology, 70(1964), pages 73-80. application by watering or dripping, it is even possible to 0436. A synergistic effect in fungicides is always present reduce the application rate, especially when inert Sub when the fungicidal action of the active compound combina strates Such as rockwool or perlite are used); tions exceeds the expected action of the active compounds. 0426 in the case of seed treatment: from 2 to 200g per 0437. The expected fungicidal action for a given combi 100 kg of seed, preferably from 3 to 150g per 100 kg of nation of two or three active compounds can be calculated as seed, more preferably from 2.5 to 25 g per 100 kg of follows, according to S. R. Colby (“Calculating Synergistic seed, even more preferably from 2.5 to 12.5g per 100 kg and Antagonistic Responses of Herbicide Combinations'. of seed; Weeds 1967, 15, 20-22): 0427 in the case of soil treatment: from 0.1 to 10 000 0438. If g/ha, preferably from 1 to 5000 g/ha. 0439 X is the efficacy when employing active compound A at an application rate of in g/ha, 0428 These application rates are merely by way of 0440 Y is the efficacy when employing active compound example and are not limiting for the purposes of the invention. B at an application rate of ng/ha and 0429. The inventive mixtures or compositions can thus be 0441 E is the efficacy when employing active compounds used to protect plants from attack by the pathogens mentioned A and B at application rates of in and ng/ha, for a certain period of time after treatment. The period for 0442 then E=X+Y(X*Y)/100 which protection is provided extends generally for 1 to 28 0443 Here, the efficacy is determined in %.0% means an days, preferably for 1 to 14 days, more preferably for 1 to 10 efficacy which corresponds to that of the control, whereas an days, most preferably for 1 to 7 days, after the treatment of the efficacy of 100% means that no infection is observed. plants with the mixtures or compositions, or for up to 200 0444 If the actual fungicidal action exceeds the calculated days after a seed treatment. value, the action of the combination is Superadditive, i.e. a 0430. The method of treatment according to the invention synergistic effect is present. In this case, the actually observed also provides the use or application of compounds according efficacy must exceed the value calculated using the above to formula (I) and one biological control agent as defined formula for the expected efficacy (E). above in a simultaneous, separate or sequential manner If the 0445. The invention is illustrated by the examples below. single active ingredients are applied in a sequential manner, However, the invention is not limited to the examples i.e. at different times, they are applied one after the other 1. A composition, comprising within a reasonably short period. Such as a few hours or days. (1) at least one compound of formula (I) Preferably the order of applying the compounds according to formula (I) and the biological control agent as defined above is not essential for working the present invention. (I) 0431. The plants listed can particularly advantageously be treated in accordance with the invention with the inventive R2 O mixtures or compositions. The preferred ranges stated above / N s for the mixtures or compositions also apply to the treatment of N H these plants. Particular emphasis is given to the treatment of N plants with the mixtures or compositions specifically men N R1 tioned in the present text. 0432. According to another aspect of the present inven tion, in the combination or composition according to the wherein invention, the compound ratio A/B may be advantageously R" represents a hydrogen atom or a methyl group and chosen so as to produce a synergistic effect. The term syner R represents a methyl group, a difluoromethyl group gistic effect is understood to mean in particular that defined or a trifluoromethyl group; and by Colby in an article entitled “Calculation of the synergistic (2) at least one biological control agent. US 2015/02824.83 A1 Oct. 8, 2015

2. A composition according to claim 1, whereby the com 5. The composition according to claim 1, whereby the pound of formula (I) is represented by one of the compounds biological control agent is selected from (I-1) to (I-5): 1) bacteria consisting of (1.1) Agrobacterium radiobacter, (1.2) Bacillus acidocaldarius, (1.3) Bacillus acidoter restris, (1.4) Bacillus agri, (1.5) Bacillus aizawaii, (1.6) (I-1) Bacillus albolactis, (1.7) Bacillus alcalophilus, (1.8) Bacillus alvei, (1.9) Bacillus aminoglucosidicus, (1.10) Bacillus aminovorans, (1.11) Bacillus amylolyticus (also known as Paenibacillus amylolyticus), (1.12) Bacillus amyloliquefaciens, in particular strain IN937a, (1.13) Bacillus amyloliquefaciens, optionally strain FZB42 (product known as RhizoVital(R), (1.14) Bacil (I-2) lus amyloliquefaciens strain B3, (1.15) Bacillus aneurinolyticus, (1.16) Bacillus atrophaeus, (1.17) Bacillus azotoformans, (1.18) Bacillus badius, (1.19) Bacillus cereus, optionally spores of Bacillus cereus strain CNCM I-1562 (cf. U.S. Pat. No. 6,406,690), (1.20) Bacillus chitinosporus, optionally strain AQ746 (Accession No. NRRL B-21618), (1.21) Bacillus circu lans (1.22) Bacillus coagulans, (1.23) Bacillus fastidio (I-3) sus, (1.24) Bacillus firmus, optionally strain I-1582 (Bionem, VOTIVO), (1.25) Bacillus kurstaki, (1.26) Bacillus lacticola, (1.27) Bacillus lactimorbus, (1.28) Bacillus lactis, (1.29) Bacillus laterosporus (Brevibacil lus laterosporus), (1.30) Bacillus lautus, (1.31) Bacillus lentimorbus, (1.32) Bacillus lentus, (1.33) Bacillus licheniformis, (1.34) Bacillus maroccanus, (1.35) Bacil lus megaterium (products known as BioArc), (1.36) (I-4) Bacillus metiens, (1.37) Bacillus mycoides, optionally strain AQ726 (Accession No. NRRL B21664), (1.38) Bacillus mycoides isolate J (BimJ), (1.39) Bacillus natto, (1.40) Bacillus nematocida, (1.41) Bacillus nigrificans, (1.42) Bacillus nigrum, (1.43) Bacillus pantothenticus, (1.44) Bacillus popillae (Cronox), (1.45) Bacillus psy chrosaccharolyticus, (1.46) Bacillus pumilus, option ally strain GB34 (products known as Yield Shield), (I-5) (1.47) Bacillus pumilus, optionally strain QST2808 (Accession No. NRRL B-30087, Sonata QST 2808(R), (1.48) Bacillus pumilus, optionally strain AQ717 (Ac cession No. NRRL B21662), (1.49) Bacillus siamensis, (1.50) Bacillus Smithii, (1.51) Bacillus sphaericus (Vec toLexs(R), (1.52) Bacillus subtilis, particular optionally strain GB03 (KodiakR), (1.53) Bacillus subtilis, option ally strain QST713/AQ713 (Accession No. NRRL B-21661, Serenade QST 713(R, Serenade Soil, Serenade 3. A composition according to claim 1, whereby the com Max), (1.54) Bacillus subtilis, optionally strain AQ743 pound of formula (I) is represented by compound (I-6): (Accession No. NRRL B-21665), (1.55) Bacillus subti lis, optionally strain AQ 153 (ATCC accession No. 55614), (1.56) Bacillus subtilis var. amyloliquefaciens (I-6) strain FZB24(Taegro (R), (1.57) Bacillus thuringiensis var. israelensis (VectoBacR), (1.58) Bacillus thuring iensis subsp. aizawai strain ABTS-1857 (XenTari(R), (1.59) Bacillus thuringiensis subsp. kurstaki strain HD-1 (Dipel(RES), (1.60) Bacillus thuringiensis subsp. Kurstaki strain BMP 123, (1.61) Bacillus thuringiensis Y. subsp. tenebrionis strain NB 176 (Novodor R FC), 2'-/ (1.62) Bacillus thuringiensis var. aegypti (products known as Agerin), (1.63) Bacillus thuringiensis var. collmeri (Tian BaoBTc), (1.64) Bacillus thuringiensis 4. The composition according to claim 1, whereby the var. darmstadiensis (Baciturin, Kolepterin), (1.65) biological control agent comprises bacteria, fungi or yeasts, Bacillus thuringiensis var. dendrolimus (Dendrobacil protozoa, viruses, entomopathogenic nematodes botanical lin), (1.66) Bacillus thuringiensis var. galleriae (Entero extracts and products produced by microorganisms including bactin), (1.67) Bacillus thuringiensis var. japonensis proteins or secondary metabolites. (Buihunter), (1.68) Bacillus thuringiensis subsp. Mor US 2015/02824.83 A1 Oct. 8, 2015 44

risoni, (1.69) Bacillus thuringiensis var. San diego, optionally strain WYCD108 (ActinovateSP), (1.126) (1.70) Bacillus thuringiensis subsp. thuringiensis strain Streptomyces lydicus, optionally strain WYEC108 (Ac MPPL002, (1.71) Bacillus thuringiensis subsp. thuring tino-iron), (1.127) Streptomyces prasinus (cf. "Prasi iensis (Bikol), (1.72) Bacillus thuringiensis var. 7216 nons A and B: potent insecticides from Streptomyces (Amactic, Pethian), (1.73) Bacillus thuringiensis var. prasinus’ Applied Microbiology 1973 November ), T36 (Cahat), (1.74) Bacillus thuringiensis strain BD #32 (1.128) Streptomyces rimosus (Rhitovit), (1.129) Strep (Accession No. NRRL B-21530), (1.75) Bacillus thur tomyces Saraceticus (Clanda), (1.130) Streptomyces ingiensis strain AQ52 (Accession No. NRRL B-21619), venezuelae, (1.131) Streptomyces sp. NRRL B-301.45 (1.76) Bacillus uniflagellatus, (1.77) Bradyrhizobium (1.132) Xanthomonas campestris, (1.133) Xenorhabdus japonicum (SoySelect), (1.78) Bacillus sp. strain AQ175 luminescens, (1.134) Xenorhabdus nematophila, (ATCC Accession No. 55608), (1.79). Bacillus sp. strain (1.135) Bacillus subtilis, optionally strain QST30002/ AQ177 (ATCC Accession No. 55609), (1.80) Bacillus AQ30002 (Accession No. NRRL B-50421, cf. WO sp. strain AQ178 (ATCC Accession No. 53522), (1.81) 2012/087980), (1.136) Bacillus subtilis, optionally Brevibacillus brevis, in particular strain SS86-3, (1.82) strain QST30004/AQ30004 (Accession No. NRRL Brevibacillus brevis, optionally strain SS86-4 (1.83) B-50455, cf. WO 2012/087980), Brevibacillus brevis, optionally strain SS86-5, (1.84) 2) fungi or yeasts consisting of (2.1) Ampelomyces Brevibacillus brevis, optionally strain 2904, (1.85) quisqualis, optionally strain AQ 10 (AQ 10(R), (2.2) Brevibacillus laterosporus, optionally strain 64 (1.86) Aureobasidium pullulans, optionally blastospores of Brevibacillus laterosporus, optionally strain 1111, strain DSM14940. (2.3) Aureobasidium pullulans, (1.87) Brevibacillus laterosporus, optionally strain optionally blastospores of strain DSM 14941 or mix 1645, (1.88) Brevibacillus laterosporus, optionally tures thereof (Blossom Protect(R), (2.4) Aschersonia strain 1647 (1.89) Chromobacterium subtsugae, option alleyrodes, (2.5) Aspergillus flavus, optionally strain ally strain PRAA4-1T (Gandevo), (1.90) Delftia aci NRRL 21882 (Afla-Guard(R), (2.6) Arthrobotry's dovorans, optionally strain RAY209 (BioBoost(R), superba (Corda 1839), (2.7) Beauveria bassiana, (1.91) Lactobacillus acidophilus (Fruitsan), (1.92) optionally strain ATCC 74040 (Naturalis(R), (2.8) Beau Lysobacter antibioticus, optionally strain 13-1 (cf. Bio veria bassiana, optionally strain GHA (Mycotrol, Bot logical Control 2008, 45, 288-296), (1.93) Lysobacter aniGard), (2.9) Beauveria brongniartii (Beaupro), enzymogenes, optionally strain C3 (cf. J Nematol. 2006 (2.10) Candida oleophila, optionally strain O (Nexy(R), June; 38(2): 233-239), (1.94) Paenibacillus alvei, Aspire), (2.11) Chaetomium cupreum (Ketocin), (2.12) optionally strains III3DT-1A (Bacillus genetic stock Cladosporium cladosporioides, optionally strain H39. center, November 2001), (1.95) Paenibacillus alvei, (2.13) Conidiobolus obscurus, (2.14) Coniothyrium optionally strain III2E (Bacillus genetic Stock center, minitans, optionally strain CON/M/91-8 (Contans.(R), November 2001), (1.96) Paenibacillus alvei, in particu (2.15) Dilophosphora alopecuri (Twist Fungus(R), lar strain 46C3 (Bacillus genetic stock center, November (2.16) Entomophthora virulenta (Vektor), (2.17) 2001), (1.97) Paenibacillus alvei, optionally strain 2771 Fusarium oxysporum, optionally strain Fo47 (Bacillus genetic stock center, November 2001), (1.98) (Fusaclean), (2.18) Gliocladium catenulatum, option Paenibacillus polymyxa, (1.99) Paenibacillus popilliae, ally strain J1446 (Prestop(R) or Primastop), (2.19) Hirsu (1.100) Pantoea agglomerans, (1.101) Pasteuria pen tella thompsonii (Mycohit or ABTEC), (2.20) etrans (Pasteuria wettable powder), (1.102) Pasteuria Lagenidium giganteum (LagineXOR by AgraGuest, Inc.), usgae (EconemTM), (1.103) Pectobacterium caroto (2.21) Lecanicillium lecanii, in particular conidia of vorum (Biokeeper), (1.104) Pseudomonas aeruginosa strain KV01 (Mycotal(R), Vertialec(R), (2.22) Metarhi (Guiticid), (1.105) Pseudomonas aureofaciens (Agate zium anisopliae, optionally strain F52 (BIO 1020 or 25K), (1.106) Pseudomonas cepacia, optionally strain Met52), (2.23) Metarhizium anisopliae var. acridum M54, (1.107) Pseudomonas cepacia, optionally strain (Green Muscle), (2.24) Metarhizium flavoviride, (2.25) J82, (1.108) Pseudomonas chlororaphis, optionally Metschnikovia fructicola, optionally the strain NRRL strain MA 342 (Cedomon), (1.109) Pseudomonas fluo Y-30752 (Shemer(R), (2.26) Microsphaeropsis ochra rescens (SudoZone), (1.110) Pseudomonas proradix cea (MicroX(R), (2.27) Mucor haemelis (BioAvard), (Proradix(R), (1.111) Pseudomonas putida (Nematsid, (2.28) Muscodor albus, optionally strain QST 20799 (1.112) Pseudomonas resinovorans (Solanacure), (ArabesqueTM or AndanteTM), (2.29) Muscodor albus, (1.113) Pseudomonas syringae (Biosave), (1.114) optionally strain 620 (Accession No. NRRL 30547), Rhodococcus globerulus strain AQ719 (Accession No. (2.30) Muscodor roseus strain A3-5 (Accession No. NRRL B21663) (1.115) Serratia entomophila (In NRRL 30548), (2.31) Myrothecium verrucaria, option vadeTM), (1.116) Serratia marcescens, optionally strain ally strain AARC-0255 (DiTeraTM), (2.32) Nomuraea SRM (MTCC8708), (1.117) Serratia marcescens, rileyi, optionally strain SA86101, (2.33) Nomuraea optionally strain R35, (1.118) Streptomyces candidus rileyi, optionally strain GU87401 (2.34) Nomuraea (BioAidTM), (1.119) Streptomyces colombiensis (Myco rileyi, optionally strain SR86151, (2.35) Nomuraea side), (1.120) Streptomyces gallbus, optionally strain rileyi, optionally strain CG128, (2.36) Nomuraea rileyi, K61 (products known as Mycostop R, cf. Crop Protec optionally strain VA9101 (Kongo.(R), (2.37) Ophiostoma tion 2006, 25, 468-475), (1.121) Streptomyces galbus, piliferum, strain D97 (Sylvanex), (2.38) Paecilomyces optionally strain QST 6047, Accession No. NRRL filmosoreus, optionally strain apopka 97 (PreFeRal), 30232, (1.122) Streptomyces goshikiensis (Safegro), (2.39) Paecilomyces lilacinus, optionally spores of (1.123) Streptomyces griseoviridis (Mycostop(R), cf. Paecilomyces lilacinus strain 251 (BioAct(R), cf. Crop Microbial db of Canada), (1.124) Streptomyces laven Protection 2008, 27, 352-361), (2.40) Paecilomyces dulae (Phytolavin-300), (1.125) Streptomyces lydicus, variotii, optionally strain Q-09 (products known as US 2015/02824.83 A1 Oct. 8, 2015

Nemaquim), (2.41) Pandora delphacis, (2.42) Penicil (products known as Spodoptrin from NPP Calliope lium bilaii, optionally strain ATCC22348 (JumpStart(R), France), (4.26) Spodoptera litura (oriental leafworm PB-50, Provide), (2.43) Penicillium vermiculatum (Ver moth) NPV (Littovir), miculen), (2.44) Phlebiopsis gigantea (Rotstop), (2.45) 5) entomopathogenic nematodes consisting of (5.1) Abbre Pichia anomala, optionally strain WRL-076, (2.46) viata Caucasica, (5.2) Acuaria spp., (5.3) Agamermis Pochonia chlamydosporia, (2.47) Pseudozyma floccu decaudata, (5.4) Allantonema spp., (5.5) Amphimermis losa, optionally strain PF-A22 UL (Sporodex (R. L), spp., (5.6) Beddingia (Deladenus) Siridicola, (5.7) (2.48) Pythium oligandrum, optionally strain DV74 Bovienema spp., (5.8) Cameronia spp., (5.9) Chitwoodi (Polyversum), (2.49) Sporothrix insectorum (Sporo ella ovofilamenta, (5.10) Contorty lenchus spp., (5.11) thrix), (2.50) Talaromyces flavus, (2.51) Trichoderma Culicimermis spp., (5.12) Diplotriaena spp., (5.13) album (Bio-Zeid), (2.52) Trichoderma asperellum Empidomermis spp., (5.14) Filipievinermis leipsandra, (5.15) Gastromermis spp., (5.16) Gongylonema spp., (BIO-TAMTM), (2.53) Trichoderma asperellum option (5.17) Gynopoecilia pseudovipara, (5.18) Heterorhab ally strain ICC 012 (Bioten(R), (2.54) Trichoderma atro ditis bacteriophora (products known as B-Green), viride, optionally strain CNCM I-1237,(2.55) Tricho (5.19) Heterorhabditis baujardi, (5.20) Heterorhabditis derma gamsii (BIO-TAMTM), (2.56) Trichoderma heliothidis (products known as Nematon), (5.21) Heter gamsii, optionally mycelial fragments, conidia & orhabditis indica, (5.22) Heterorhabditis marelatus, chlamydospores of strain ICC080 (Bioderma), (2.57) (5.23) Heterorhabditis megidis, (5.24) Heterorhabditis Trichoderma harmatum, (2.58) Trichoderma har Zealandica, (5.25) Hexamermis spp., (5.26) Hydromer zianum, optionally Trichoderma harzianum T39 (Tri mis spp., (5.27) Isomermis spp., (5.28) Limnomermis chodex(R), (2.59) Trichoderma koningii (Trikot-S Plus), spp., (5.29) Maupasina weissi, (5.30) Mermis nigre (2.60) Trichodermalignorum (Mycobac), (2.61) Tricho scens, (5.31) Mesomermis spp., (5.32) Neomesomermis derma polysporum, optionally strain IMI 206039, (2.62) spp., (5.33) Neoparasity lenchus rugulosi, (5.34) Octo Trichoderma virens (SoilCiard), (2.63) Tsukamurella myomermis spp., (5.35) Parasitaphelenchus spp., (5.36) paurometabola (HeberNemR), (2.64) Ulocladium Parasitorhabditis spp., (5.37) Parasity lenchus spp., oudemansii (Botry-Zen), (2.65) Verticillium albo (5.38) Perutilimermis culicis, (5.39) Phasmarhabditis atrum, optionally strain WCS850, (2.66) Verticillium hermaphrodita, (5.40) Physaloptera spp., (5.41) Pro chlamydosporium (Varsha), (2.67) Verticillium dahliae trellatus spp., (5.42) Pterygodermatites spp., (5.43) (Dutch Trig), (2.68) Zoophtora radican, Romanomermis spp., (5.44) Seuratum cadarachense, (5.45) Sphaerulariopsis spp., (5.46) Spirura guianensis, 3) protoZoas consisting of (3.1) Nosema locustae (Nolo (5.47) Steinernema carpocapsae (Biocontrol), (5.48) Bait), (3.2) Thelohania solenopsis, (3.3) Vairimorpha Steinernema feltiae (products known as NemasyS(R), Spp, (5.49) Steinernema glaseri (Biotopia), (5.50) Stein 4) viruses consisting of (4.1) Adoxophyes Orana (Summer ernema kraussei (Larvesure), (5.51) Steinernema rio fruit tortrix) granulosis virus (GV), (BIOFA-Capex.R.), brave (BioVector), (5.52) Steinernema scapterisci (4.2) Agrotis segetum (turnip moth) nuclear polyhedro (Nematac S), (5.53) Steinernema scarabaei, (5.54) sis virus (NPV), (4.3) Anticarsia gemmatalis (Woolly Steinernema scarabaei, (5.55) Strelkovimermis peters pyrol moth) mNPV (Polygen), (4.4) Autographa Cali eni, (5.56) Subulura spp., (5.57) Sulphuretylenchus fornica (Alfalfa Looper) mNPV (VPN80 from Agricola elongatus, (5.58) Tetrameres spp., El Sol), (4.5) Biston suppressaria (tea looper) NPV. 6) proteins or secondary metabolites consisting of (6.1) (4.6) Bombyx mori (silkworm) NPV. (4.7) Cryptophle Harpin (isolated by Erwinia amylovora, products known bia leucotreta (false codling moth) GV (products known as Harp-N-TekTM, Messenger.R, EmployTM, ProActTM) as Cryptex), (4.8) Cydia pomonella (Codling moth) 7) botanical extracts consisting of (7.1) Thymol, extracted granulosis virus (GV) (Madex Plus), (4.9) Dendrolimus e.g. from thyme (thymus vulgaris), (7.2) Neem tree punctatus (Masson pine moth) CPV, (4.10) Helicoverpa (Azadirachta indica) oil, and therein Azadirachtin, (7.3) armigera NPV (AgBiTech ViVUS-Max), (4.11) Heli Pyrethrum, an extract made from the dried flower heads coverpa (previously Heliothis) zea (cornearworm) NPV of different species of the genus Tanacetum, and therein (Elcar), (4.12) Leucoma salicis (satin moth) NPV. (4.13) Pyrethrins (the active components of the extract), (7.4) Lymantria dispar (gypsy moth) NPV (Gypcheck), extract of Cassia nigricans, (7.5) wood extract of Ouas (4.14) Neodiprion abietis (balsam-fir sawfly) NPV sia amara (bitterwood), (7.6) Rotenon, an extract from (Abietiv), (4.15) Neodiprion lecontei (red-headed pine the roots and stems of several tropical and Subtropical sawfly) NPV (Lecontvirus), (4.16) Neodiprion sertifer plant species, optionally those belonging to the genera (Pine sawfly) NPV (Neocheck-S), (4.17) Orgvia Lonchocarpus and Derris, (7.7) extract of Allium sati pseudotsugata (Douglas-fir tussock moth) NPV (Vir vum (garlic), (7.8) Quillaia extract, made from the con tuss), (4.18) Phthorimaea operculella (tobacco leaf centrated purified extract of the outer cambium layer of miner) GV (Matapol), (4.19) Pieris rapae (small white) the Ouillaja Saponaria Molina tree, (7.9) Sabadilla GV. (4.20) Plutella xylostella (diamondback moth) GV (Sabadilla Schoenocaulon officinale) seeds, optionally (Plutec), (4.21) Spodoptera albula (grayStreaked army Veratrin (extracted from the seeds), (7.10) Ryania, an worm moth) mNPV (VPN 82), (4.22) Spodoptera extract made from the ground stems of Ryania speciosa, exempta (true armyworm) mNPV (Spodec), (4.23) optionally Ryanodine (the active component of the Spodoptera exigua (Sugarbeet armyworm) mNPV extract), (7.11) extract of Viscum album (mistletoe), (Spexit from Andermatt Biocontrol), (4.24) Spodoptera (7.12) extract of Tanacetum vulgare (tansy), (7.13) frugiperda (fall armyworm) mNPV (Baculovirus VPN), extract of Artemisia absinthium (wormwood), (7.14) (4.25) Spodoptera littoralis (tobacco cutworm) NPV extract of Urtica dioica (stinging nettle), (7.15) extract US 2015/02824.83 A1 Oct. 8, 2015 46

of Symphytum officinale (common comfrey), (7.16) 9. The composition according to claim 2, whereby the extract of Tropaeulum majus (monks cress), (7.17) compound of formula (I-1) is represented by the formula leaves and bark of Quercus (oak tree) (7.18) Yellow mustard powder, (7.19) oil of the seeds of Chenopodium anthelminticum (wormseed goosefoot), (7.20) dried leaves of Dryopteris filix-mas (male fern), (7.21) bark of Celastrus angulatus (Chinese bittersweet), (7.22) extract of Equisetum arvense (field horsetail), (7.23) Chitin (7.24) natural extracts or simulated blend of Che nopodium ambrosioides (Requiem), (7.25) Saponins of Chenopodium quinoa (Heads Up). 6. The composition according to claim 1, whereby the biological control agent is selected from 1) bacteria consisting of (1.24) Bacillus firmus, optionally strain I-1582 (Bionem, VOTIVO), (1.47) Bacillus pumi wherein lus, optionally strain QST2808 (Accession No. NRRL R" represents a hydrogen atom or a methyl group and B-30087, Sonata QST 2808(R), (1.52) Bacillus subtilis, R represents a methyl group, a difluoromethyl group or optionally strain GB03 (Kodiak.R.), (1.53) Bacillus sub a trifluoromethyl group. tilis, optionally strain QST713/AQ713 (Accession No. 10. A method for controlling one or more harmful micro NRRL B-21661, Serenade QST 713(R, Serenade Soil, organisms or pests, comprising contacting said microorgan Serenade Max), (1.135) Bacillus subtilis, optionally isms or pests and/or a habitat thereof with a composition according to claim 1. strain QST30002/AQ30002 (Accession No. NRRL 11. A method for treating seeds, comprising contacting B-50421, cf. WO 2012/087980), (1.136) Bacillus subti said seeds with a composition according claim 1. lis, optionally strain QST30004/AQ30004 (Accession 12. A process for preparing a composition, comprising No. NRRL B-50455, cf. WO 2012/087980), mixing a composition according to claim 1 with an extender, 2) fungi or yeasts consisting of (2.20) Lagenidium gigan a Surfactant or a combination thereof. teum (LagineXCR by AgraQuest, Inc.), (2.52) Tricho 13. A seed treated with a composition according to claim 1. derma asperellum (BIO-TAMTM), (2.55) Trichoderma 14. Method for protection of one or more plants and/or gamsii (BIO-TAMTM) and 7) botanical extracts consist plant parts against unwanted microorganisms, comprising ing of (7.24) natural extracts or simulated blend of Che two or more steps of treatment: nopodium ambrosioides (Requiem) a) with a compound of formula (I) 7. The composition according to claim 1, whereby the biological control agent is selected from 1) bacteria consisting of (1.58) Bacillus thuringiensis (I) subsp. aizawai strain ABTS-1857 (XenTari(R) or (1.59) Bacillus thuringiensis subsp. Kurstaki strain HD-1 R2 O (Dipel(R) ES). / N s 8. The composition according to claim 2, whereby the N H compound of the formula (I-1) is represented by formula N N R1

wherein R" represents a hydrogen atom or a methyl group and R represents a methyl group, a difluoromethyl group or a trifluoromethyl group and b) at least one biological control agent, wherein the two components are applied separately to the plant and/or plant part at the same or different plant growth stages including post harvest treatment and wherein the application of a) and b) is not limited to a wherein special order or number of applications. R" represents a hydrogen atom or a methyl group and 15. A method of claim 12, wherein the composition com R represents a methyl group, a difluoromethyl group or prises a synergistically effective mixture. a trifluoromethyl group. k k k k k