springer.com

Nicholas Mantis (Ed.) and Shiga Pathogenesis, Immunity, Vaccines and Therapeutics Series: Current Topics in Microbiology and Immunology

In May of 2011, Western Europe experienced a severe outbreak of Shiga (Stx)-producing E. coli (STEC) that culminated in more than 3200 cases and 39 deaths. While Stx is not the only factor associated with STEC, it is certainly the primary determinant associated with the onset of hemolytic uremic syndrome (HUS). At the present time, there are no clinically approved measures to neutralize Stx in individuals suffering from STEC infection. Nor are there any preventatives or therapeutics for ricin toxin. Although incidents of ricin exposure are largely unheard of, federal agencies and public health officials consider it a significant threat. It is well documented that domestic and international terrorist groups have stockpiled, and in some cases weaponized ricin with the intent of releasing it into the public sphere and causing panic, illness and/or death on a local, regional, or possibly national scale. The chapters, written by leading experts in the field, are organized so as to cover all aspects of ricin and Stx, including pathogenesis, immunity, vaccines and therapeutics. This outstanding 2012, XII, 276 p. collection of reviews will serve as an important and readily accessible resource for the research community in the coming years. Printed book Hardcover 199,99 € | £179.99 | $249.99 [1]213,99 € (D) | 219,99 € (A) | CHF 236,00 Softcover 186,90 € | £139.99 | $219.99 [1]199,98 € (D) | 205,59 € (A) | CHF 220,50 eBook 149,79 € | £111.50 | $169.00 [2]149,79 € (D) | 149,79 € (A) | CHF 176,00 Available from your library or springer.com/shop MyCopy [3] Printed eBook for just € | $ 24.99 springer.com/mycopy

Order online at springer.com / or for the Americas call (toll free) 1-800-SPRINGER / or email us at: [email protected]. / For outside the Americas call +49 (0) 6221-345-4301 / or email us at: [email protected]. The first € price and the £ and $ price are net prices, subject to local VAT. Prices indicated with [1] include VAT for books; the €(D) includes 7% for Germany, the €(A) includes 10% for Austria. Prices indicated with [2] include VAT for electronic products; 19% for Germany, 20% for Austria. All prices exclusive of carriage charges. Prices and other details are subject to change without notice. All errors and omissions excepted. [3] No discount for MyCopy.

Part of