Wael N. Sayej, M.D., MBA, FAAP Department of Pediatrics Chief, Pediatric Gastroenterology and Nutrition Baystate Children's Specialty Center 50 Wason Avenue Springfield, MA 01199 (413) 794-2305 [email protected] 06/09/2021

Education Graduate School (MBA) 08/2010-12/2019 University of Connecticut School of Business - Part-time MBA Program Master in Business Administration: Concentrations: Healthcare and Management

Medical School (MD) 08/1996 - 11 /2000 Our Lady of Fatima University Fatima College of Medicine Valenzuela City, Philippines Degree: Doctor of Medicine (MD)

Undergraduate Education (BS) 09/1992 - 05/1996 College of Mount Saint Vincent (CMSV) Riverdale, NY Major: Biology/Pre-Med with a concentration in Molecular Biology Minor: Mathematics Degree: Bachelor of Science

Postdoctoral Training

Fellowship Training 07 /2006 - 06/2009 Pediatric Gastroenterology, Hepatology and Nutrition Digestive Diseases and Nutrition Center Women & Children's Hospital of Buffalo University at Buffalo, Buffalo, NY

Internship and Residency Training 07/2003 - 06/2006 Pediatrics UMDNJ - New Jersey Medical School (Rutgers University) Newark, NJ Affiliate Hospital: Hackensack University Medical Center Hackensack, NJ

Academic Appointments Associate Professo·r of Pediatrics 03/2021 - Current University of Massachusetts Medical School - Baystate Worcester, MA

Associate Professor of Pediatrics 09/2018-11/2019 University of Connecticut School of Medicine Updated: December 11, 2020 Page 2 of 15

Farmington, CT

Assistant Professor of Pediatrics 07/2009- 09/2018 University of Connecticut School of Medicine Farmington, CT

Other Positions and Employment Attending Physician - Pediatric Gastroenterologist 07/2009 - 11/2019 Division of Digestive Diseases, Hepatology & Nutrition Connecticut Children's Medical Center, Hartford, CT

Pediatric Advisory Committee for the FDA 09/ 2016 - Present Special Government Consultant

Associate Medical Staff 05/2013-2016 Department of Pediatrics Connecticut Children's Medical Center Saint Mary's Hospital, Waterbury, CT

Consultant, Pediatric Gastroenterologist 02/2011 - 11/2019 Department of Pediatrics Danbury Hospital, Danbury, CT

Major Leadership Positions Division Chief - Pediatric Gastroenterologist 11/2019- Present Division of Pediatric Gastroenterology & Nutrition UMMS-Baystate Dept. Pediatrics and Baystate Children's Hospital Springfield, Massachusetts

Educational Activities Educational Leadership, Administration and Service

Director, Pediatric Gastroenterology Fellowship Program 08/2014- 01/2018 Department of Pediatrics Division of Digestive Diseases, Hepatology & Nutrition Connecticut Children's Medical Center, Hartford, CT University of Connecticut School of Medicine

Associate Director, Pediatric Gastroenterology Fellowship Program 09/2009 - 08/2014 Department of Pediatrics Division of Digestive Diseases, Hepatology & Nutrition Connecticut Children's Medical Center, Hartford, CT University of Connecticut School of Medicine

Director, Pediatric GI/Radiology/Surgery CME Activity 2011 - 2018 Department of Pediatrics Division of Digestive Diseases, Hepatology & Nutrition Connecticut Children's Medical Center, Hartford, CT University of Connecticut School of Medicine Page 3 of 15

Director, Pediatric GI/Pathology CME Activity 2011 -2018 Department of Pediatrics Division of Digestive Diseases, Hepatology & Nutrition Connecticut Children's Medical Center, Hartford, CT University of Connecticut School of Medicine

Teaching Activities in Programs and Courses

University of Massachusetts Medical School-Baystate, Springfield, MA Autoimmune Hepatitis 03/25/2021 Baystate Children's Hospital ED Residents and Staff Didactics Lecture

Lower GI Bleeding in Children 12/02/2020 1 Baystate Children's Hospital ED Residents and Staff Didactics Lecture

Gastroesophageal reflux in infants and Children 07/22/2020 in Children Functional Gastrointestinal Disorders in Children Baystate Children's Hospital ED Residents and Staff Didactics Lecture

Cystic Fibrosis associated Gastrointestinal Issues 05/07/2020 Baystate Children's Hospital Pediatric Residency Academic Half Day Lecture

Celiac Disease 03/12/2020 Baystate Children's Hospital Pediatric Residency Academic Half Day Lecture

Other "Gastroesophageal Reflux in Infants and Children" 02/08/2018 University of Saint Joseph, West Hartford, CT Physician Assistant Program, Gastrointestinal Diseases and Nutrition Lectures

Advanced Clinical Problem-Solving Elective 07/10/2017 USMLE Step 2 CK Board Review Elective course for 4th year medical students - UCONN

Advanced Clinical Problem-Solving Elective 07/21/2016 USMLE Step 2 CK Board Review Elective course for 4th year medical students - UCONN

"Gallbladder and Pancreatic Disease in Children" 12/18/2015 Resident didactic lecture - Connecticut Children's Medical Center Page 4 of 15

Advanced Clinical Problem-Solving Elective 0/7/23/2015 USMLE Step 2 CK Board Review Elective course for 4th year medical students - UCONN

"Acute and Chronic Pancreatitis" 05/05/2015 Presented to the Department of Pediatric Gastroenterology

Advanced Clinical Problem-Solving Elective 07/11/2014 USMLE Step 2 CK Board Review Elective course for 4th year medical students - UCONN

"Syndromes with GI Manifestations" 08/03/2012 Resident didactic lecture - Connecticut Children's Medical Center

"Enteral Nutrition: The Alternatives" 02/06/2012 Presentation on enteral nutrition and feeding tubes given to Dentistry Residents at Connecticut Children's

" and Bilirubin Metabolism" 09/02/2011 Resident didactic lecture - Connecticut Children's Medical Center

"Childhood Obesity" 02/19/2009 Resident didactic lecture - Connecticut Children's Medical Center

Education for the Public/Community Education 1. "Food Allergies: Facts, Fads and Myth-Conceptions" 01/10/2018 The Children's Museum - West Hartford, CT

Investigation

Grants • NIH/SBIR (Finck, Pl) 4/01/2018- 2019 - A retrievable autologous bioengineered esophageal implant as a novel treatment for long­ gap esophageal atresia (R44) - Purpose of this grant is to explore the use of a retrievable scaffold as a way to treat pediatric esophageal defects and injuries using Biostage's cellspan esophageal implant. - Role: Clinical Advisor (5%) - Direct costs: $747,782

Completed 7/01/2013- 6/30/2016 • CCMC Friends (Sayej, Pl) Adopt-a-Program grant (CCMC Friends) "Endoscopic phenotypes in patients with eosinophilic esophagitis are associated with unique molecular fingerprints: a pilot study" Direct costs: $25,000 Page 5 of 15

Health Care Delivery Leadership Positions Investigator Site Champion for I-Act 2020 - Present Institute for Advanced Clinical Trials Baystate Health

Director, Pediatric Procedure Unit Nov 2019 - Present Division of Pediatric Gastroenterology & Nutrition Baystate Children's Hospital Springfield, Massachusetts

Regional Medical Director for GI and Nutrition Sept 2018 - Nov 2019 Connecticut Children's Subspecialty Group Connecticut Children's Medical Center, Hartford; CT

Director, Eosinophilic Esophagitis Program and Center 03/2015 - 11/2019 Division of Digestive Diseases, Hepatology & Nutrition Connecticut Children's Medical Center, Hartford, CT

Director, Pediatric Capsule Endoscopy 10/2009 - 11/2019 Division of Digestive Diseases, Hepatology & Nutrition Connecticut Children's Medical Center, Hartford, CT

Co-director, Connecticut Children's Aerodigestive Team (CCAT} 02/2012-07/2014 Division of Digestive Diseases, Hepatology & Nutrition Connecticut Children's Medical Center, Hartford, CT A collaborative team: departments of Gastroenterology, Pulmonology and ENT

Certification and Licensure

• Commonwealth of Massachusetts Board of Registration in Medicine 2019 - Present

• Commonwealth of Massachusetts - Controlled Substance Registration 2019 - Present

• State of Connecticut Medical License 2008 - Present

• Sta~e of Connecticut Controlled Substance Registration 2009 - 02/2020

• Federal DEA License 2008 - Present

• New York State Unrestricted Medical License 2006-2017

• Ohio State Training Medical License (Training License) Page 6 of 15

Certifications • Certified: Subspecialty of Pediatric Gastroenterology 2011 - Present

• Certified: American Board of Pediatrics 2007-2017

• MOC cycle 2017 - Present

• National Board of Physicians and Surgeons (NBPAS) 2014 - Present

Scholarship

Peer-reviewed publications Asterisk (*) is for corresponding author (i.e. the person most responsible for the contents of the manuscript) as listed in the journal.

1. Robson, J. *, Lusman, S.S., Lee, C. K., Merves, J., Middleton, J., Perez, M. E., Desai, N. K., Sayej, W., Sivagnanam, M., Solomon, A. 8., Colombo, J. M., Rosen, J.M., Van Buren, K. W., Brown, J. 8., Turmelle, Y. P., Cerezo, C. S., Loomes, K. M., Huang, J. S., Quiros-Tejeira, R. E., Benkov, K., ... Sauer, C. G. (2020). Pediatric Gastroenterology, Hepatology, and Nutrition Entrustable Professional Activities: Development of an Assessment Tool and Curricular Resources. Journal of pediatric gastroentero/ogy and nutrition, 71(1 ), e40-e45. PMID: 31988878

2. Wong J, Goodine S, Samela K, Vance KS, Chatfield 8, Wang Z, Sayej WN*. Efficacy of Dairy Free Diet and 6-Food Elimination Diet as Initial Therapy for Pediatric Eosinophilic Esophagitis: A Retrospective Single-Center Study. Pediatr Gastroenterol Hepatol Nutr. 2020 Jan;23(1 ):79-88. Epub 2020 Jan 9. PMID: 31988878

3. Sayej WN*, lsakoff MS, DiGiuseppe JA, Moote D, Balarezo F, Finck C, Hyams JS. Primary Cutaneous Follicle Center Lymphoma in a 16-Year-Old Male with Crohn's Disease Exposed to lnfliximab and Methotrexate. J Pediatr Gastroenterol Nutr. 2019 Nov 26. [Epub ahead of print]. PMID: 31789777

4. Jensen T*, Wanczyk H, Sharma I, Mitchell A, Sayej WN, Finck C. Polyurethane scaffolds seeded with autologous cells can regenerate long esophageal gaps: An esophageal atresia treatment model. J Pediatr Surg. 2018 Oct 22. PMID: 30429066

5. Mink R*, Schwartz A, Carraccio C, et. al.; Steering Committee of the Subspecialty Pediatrics Investigator Network. Creating the Subspecialty Pediatrics Investigator Network. J Pediatr. 2018 Jan;192:3-4.e2. PMID: 29895838 (Role: Collaborator)

6. Sayej WN*, Foster C, Jensen T, Chatfield S, Finck C. Expanding and characterizing esophageal epithelial cells obtained from children with eosinophilic esophagitis. Pediatr Res. 2018 June 12. PMID: 29895838

7. Fable JM, Fernandez M, Goodine S, Lerer T, Sayej WN*. Retrospective comparison of fluticasone propionate and oral viscous budesonide in children with eosinophilic esophagitis. J Pediatr Gastroenterol Nutr. 2017 May 9. PMID: 28489670. Page 7 of 15

8. Alkhouri RH*, Bahia G, Smith AC,Thomas R, Finck C, Sayej W. Outcome of medical management of intraabdominal abscesses in children with Crohn's disease. J Pediatr Surg. 2017 Mar 30. pii: S0022-3468(17)30208-7. PMID: 28427855

9. Jensen T J*, Foster C, Sayej W, Finck CM. Conditional reprogramming of pediatric human esophageal epithelial cells for use in tissue engineering and disease investigation. J Vis Exp. 2017 Mar 22;(121 ). PMID: 28362412.

10. Grossi V*, Bezler N, Sayej WN. An ulcer of the duodenum in an adolescent caused by a pancreatic neuroendocrine tumor. Clin Gastroenterol Hepatol. 2016 Sep 6. PMID: 27613258.

11. Sayej WN*, Menoret A, Maharjan AS, Fernandez M, Wang Z, Balarezo F, Hyams JS, Sylvester FA, Vella AT. Characterizing the inflammatory response in esophageal mucosal biopsies in children with eosinophilic esophagitis. Clin Transl lmmunol. 2016; 5:e88. PMID: 27525061.

12. Sayej WN*, Knight PR 111, Guo WA, Mullan B, Ohtake PJ, Davidson BA, Khan A, Baker RD, Baker SS. Advanced glycation end products induce obesity and hepatosteatosis in CD-1 wild-type mice. BioMed Res Int. 2016;2016. Article ID 7867852. PMID: 26942201.

13. Semancik E, Sayej WN*. Oral immunotherapy for peanut allergy induces eosinophilic esophagitis: three pediatric case reports. Pediatr Allergy lmmunol. 2016 Feb 17. PMID: 26888330.

14. Jensen T*, Blanchette A, Vadasz S, Dave A, Canfarotta M, Sayej WN, Finck C. Biomimetic and synthetic esophageal tissue engineering. Biomaterials. 2015 Jul; 57:133-41. PMID: 25916501.

15. Hollander LL*, Girard ED, Ruscher K, Sayej W, Finck C. Infected urachal cyst secondary to a Crohn's enterourachal fistula. J Pediatr Surg. 2012. PMID: 23217916.

16. Schaufler C*, Lerer T, Campbell B, Weiss R, Cohen J, Sayej W, Hyams J. Pre-operative immunosuppression is not associated with increased post-operative complications following colectomy in children with ulcerative colitis. J Pediatr Gastroenterol Nutr. 2012 Oct; 55(4):421-4. PMID: 22395189.

17. Patel R*, Baker SS, Sayej WN, Baker R. Two cases of helicobacter pylori-negative gastric outlet obstruction in children. Case Rep Gastrointest Med. 2011 ;2011. Article ID 749850. PMID: 22606426.

18. Sayej WN*, Alkhouri R, Baker RD, Patel R, Baker SS. Esophagitis in children with celiac disease. ISRN Gastroenterol. 2011; 2011 :489065. PMID: 21991513.

19. Baker SS*, Faden H, Sayej W, Patel R, Baker RD. Increasing incidence of community-associated atypical Clostridium difficile disease in children. Clin Pediatr (Phila). 2010 Jul; 49(7):644-7. Epub 2010 Feb 11. PMID: 20150212.

20. Sayej W*, Patel R, Baker RD, Tron E, Baker SS. Treatment with high-dose proton pump inhibitors helps distinguish eosinophilic esophagitis from non-eosinophilic esophagitis. J Pediat Gastroenterol Nutr. 2009 Oct; 49(4):393-9. PMID: 19633574.

Books & Chapters 1. Todd Jenson, Christine M. Finck, Wael N. Sayej. Esophageal Tissue Engineering. In: Frontiers in Science & Regenerative Medicine - Edition 3, Chapter 7. Publisher: Bentham Science. June 2016 Page 8 of 15

2. Grossi V, Sayej WN*. Colitis. In: Christine Waasdorp Hurtado, B. U. K. Li . The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition. 2nd ed. [E-book] NASPGHAN, 2016

3. Grossi V, Sayej WN*. Radiation oncology. In: Christine Waasdorp Hurtado, B. U. K. Li. The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition. 2nd ed. [E-book] NASPGHAN, 2016

4. Mokha J, Sayej WN*. and gas. In: Christine Waasdorp Hurtado, B. U. K. Li, The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition. 2nd ed. [E-book] NASPGHAN, 2016

5. Mokha J, Sayej WN*. Appendicitis. In: Christine Waasdorp Hurtado, B. U. K. LiThe NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition. 2nd ed. [E-book] NASPGHAN, 2016

I 6. Pressley-Wallace A, Sayej WN*. Chronic constipation and encopresis. In: Christine Waasdorp Hurtado, B. U. K. Li, The NASPGHAN Fellows Concise Review of Pediatric Gastroenterology, Hepatology and Nutrition. 2nd ed. [E-book] NASPGHAN, 2016

7. Todd J, Sayej WN, Finck C. Esophageal tissue engineering. In: Atta-ur-Rahman, Shazia Anjum, Frontiers in stem cell and regenerative medicine. Vol 3. United Arab Emirates: Bentham Science; [E-book], 11-04-2015-Ebk series/FSCRMR/EOl-59.

8. Schaufler C, Moote D, Sayej W*. and peritonitis. In: Pohl JF, Jolley C, Gelfond D, Pediatric gastroenterology (a color handbook). 1st ed. CRC Press; May 27, 2014.

Non-Peer-reviewed publications

Wael N. Sayej, MD*, John Fisher, MD, Susan S. Baker MD, PhD. Two teens with retrosternal chest pain and . Case report of two teens with minocycline-induced esophagitis. Consultant for Pediatricians. 2008 Aug; 7(8): 329-34.

Invited Presentations

International 1. "The Saga: Differentiating Eosinophilic Esophagitis vs. Gastroesophageal 05/27-29/2015 Reflux Disease" Invited speaker: The E'lite Pediatric GI Congress, Dubai, UAE Oral Presentation

National 1. Philippine Pediatric Society of America 10/15/2016 Invited speaker: "Inflammatory Bowel Disease in Children," Newark, NJ Oral Presentation 2. "The Internet and Your Child with IBD: The Good, The Bad and the Ugly" 10/03/2010 Invited speaker: Pediatric IBD Day 2010 - Manhattan, NY CCFA sponsored program; Manhattan, NY Oral Presentation Page 9 of 15

3. "Phlegmons in Children with Crohn's Disease" 04/2009 Presented at the Pediatric IBD Workshop, San Diego, CA

4. "Biomarkers in Non-Alcoholic Steatohepatitis" 04/2009 Presentation, 3rd Year Fellows Conference, Scottsdale, AZ

Regional 1. "Pediatric GI Poop-Pourri" 10/21/2015 Invited speaker: Con·necticut Academy of Family Physician's (CAFP), Plantsville, CT Oral Presentation

2. "Failure to Thrive in Infants and Children" 04/28/2015 Grand Rounds presentation, Saint Mary's Hospital, Waterbury, CT

3. "Diagnosis & Management of Gastroesophageal Reflux in Pediatric 01/28/2014 Patients" Grand Rounds presentation, Saint Mary's Hospital, Waterbury, CT

4. "Eosinophilic Esophagitis: What We Know in 201 0" 09/25/2010 Invited speaker: The Connecticut Society of Gastroenterology Nurses and Associates (CTSGNA) Annual Seminar - Beyond the Scope 2010 Hartford, CT

5. "Phlegmons" in children with Crohn's disease: case series and dis'cussion 11/2008 2nd Upstate Pediatric Gastroenterology Conference, Skaneateles, NY

Local 1. "Common Gastrointestinal Causes of Feeding Difficulties in Infants and 03/09/2019 Children" Clinical Assessment and Intervention for Pediatric Feeding Problems Conference, Hartford, CT, Conference sponsor: Connecticut Children's Medical Center

2. "Eosinophilic Esophagitis: Recognition; Diagnosis and Treatment" 10/19/2018 Grand Rounds presentation, Danbury Hospital, Danbury, CT

3. Building Brighter Futures Conference 04/07/2017 Invited speaker: uThe Nuts and Grains of Eosinophilic Esophagitis," Mystic, CT, Oral Presentation. Conference sponsor: Connecticut Children's Medical Center

4. "Gastroesophageal Reflux in Infants and Children" 04/03/2015 Grand Rounds presentation, Danbury Hospital, Danbury, CT

5. "Reflux and Aerodigestive Disorders in Children" 02/20/2013 Presentation to the Speech Department at Connecticut Children's Medical Center Page 10 of 15

6. "Connecticut Children's Aerodigestive Team" 02/19/2013 Grand Rounds presentation, Connecticut Children's Medical Center

7. "Celiac Disease" 02/17/2012 Grand Rounds presentation, St. Francis Hospital, Hartford, CT

8. "Eosinophilic Esophagitis: An Emerging Disease" 01/11/2012 Grand Rounds presentation, Day Kimball Hospital, Putnam, CT

9. "Eosinophilic Esophagitis: An Emerging Disease" 11/22/2011 Grand Rounds presentation, Danbury Hospital, Danbury, CT

10. "Approach to Lower Gastrointestinal Bleeding in Children" 05/18/2010 Grand Rounds presentation, Connecticut Children's Medical Center

11. "Phlegmons" in children with Crohn's disease: case presentation 10/2008 Inter-City Inter-Departmental IBD Quarterly Conference, Buffalo, NY Conference sponsor: Women and Children's Hospital of Buffalo

12. "Infantile Botulism - Report of 2 Cases" 03/2006 Grand Rounds, UMDNJ-New Jersey Medical. School

13. "How to Evaluate the Child with Fever" 01/2006 Grand Rounds, UMDNJ-New Jersey Medical School

Other Presentations, Posters & Abstracts

National 1. "A Cytokine Signature from Esophageal Mucosa Differentiates 10/12/2013 Eosinophilic Esophagitis from Gastroesophageal Reflux Disease" Oral presentation: NASPGHAN meeting, Chicago, IL

2. "Prevalence of Esophagitis in Children with Celiac Disease" 11/2008 Oral presentation: NASPGHAN meeting, San Diego, CA

3. "High-Dose Acid Suppression Distinguishes Severe Reflux Esophagitis 05/2008 from Eosinophilic Esophagitis" - Abstract #415 Oral presentation: Digestive Diseases Week 2008, San Diego, CA

Local Presentations 1. "I am in Remission - Can I stop my Medication?" 6/24/2020 CCF Symposium Springfield, MA - New England Chapter Zoom Oral Presentation

2. "\iyhat's on your plate?: Diet focus on maintaining remission and treating 11/06/2019 symptoms" CCF - Patient and Family IBD Symposium Holyoke, MA Oral Presentation Page 11 of 15

3. "What's on your plate?: Diet focus on maintaining remission and treating 04/28/2019 symptoms" CCF - Connecticut Patient and Family IBD Symposium Sheraton Hartford South Hotel, Rocky Hill, CT Oral Presentation

4. "Management of IBD in Children" 10/18/2018 CCF - Hartford Patient & Family Education Program Bethany Lutheran Church, West Hartford, CT Oral Presentation

5. "What's On your Plate: Diet, Nutrition and IBD" 04/29/2018 CCF - Connecticut Patient & Family IBD Symposium Courtyard by Marriott, Cromwell, CT Oral Presentation

6. "Management of IBD in Pediatrics" 04/30/2017 CCF - Connecticut Patient & Family IBD Symposium Courtyard by Marriott, Cromwell, CT Oral Presentation

7. "Management of IBD in Pediatrics" 04/03/2016 CCFA- Connecticut Patient & Family IBD Symposium Courtyard by Marriott - Cromwell, CT Oral Presentation

8. "Painless Gastrointestinal Bleeding in Children" 04/07/2010 Presented at the "Update in Pediatric Gastroenterology" to community pediatricians, Shelton, CT Oral Presentation

9. "The Internet and IBD: What You Need to Know" 10/24/2009 Presented at the 4th Annual IBD Symposium - Hartford, CT Oral ,Presentation

Abstracts/Posters 1. Foster, Christopher; Chatfield, Sydney; Jersen, Todd; Wang, Zhu; Finck, Christine, Sayej, Wael N. A gene expression array as a diagnostic test in pediatric Eosinophilic esophagitis. [poster presentation Sa1165-2018]; DDW; 2018; Washington, DC.

2. Pressley-Wallace A., Foster C., Chatfield S.; Sayej WN. The IL-10/ll-5 ratio as a potential tool for monitoring the inflammatory process in eosinophilic esophagitis. [poster presentation]; NASPGHAN; 2017; Las Vegas, NV.

3. Wong J., Sayej WN. Clinical aspects of dietary therapy in children with Eosinophilic esophagitis. [poster presentation); NASPGHAN; 2017; Las Vegas, NV.

4. Hajjat T., Weber B., Mohr F., Sayej WN. Utility of video capsule endoscopy in pediatric patients: A single center experience. [poster presentation]; NASPGHAN; 2017; Las Vegas, NV.

5. BradleyJerson, Barbara Rzepski, Zev Davidovics, Karan Emerick, Melissaa Fernandes, Franziska Mohr, Jasmeet Mokha, Kristin Philipp, Wael Sayej, Heidi Sweeney, Peter Townsend, Bella Zeisler, Page 12 of 15

Jeffrey Hyams. "We agree, It's not in your head" The successes and challenges of integrating psychosocial care: A review of one year with an embedded pediatric psychologist. [poster presentation]; NASPGHAN; 2017; Las Vegas, NV.

6. Jensen T, Mitchell A, Sharma I, Sayej W, Finck C. Synthetic scaffolding and amniotic fluid mesenchymal stem cells: a new surgical option for long gap esophageal atresia?. CAPS [podium presentation]; 2017 Oct 5-7; Alberta, Canada.

7. Jensen T, Mitchell A, Sharma I, Sayej W, Finck C. Tissue engineering approaches for treating long gap esophageal atresia. NESS [podium presentation]; 2017 Sept 8-10; Bretton Woods, NH.

8. Jensen T, Mitchell A, Sayej W, LaFrancesca S, Finck C. Esophageal scaffolds seeded with epithelial cells for esophageal replacement therapy. American Pediatric Surgery Association; 2017 May; Hollywood, FL. [best poster overall: Poster with 1-Minute Oral] [best poster overall: Poster with 1-Minute Oral]

9. Pressley-Wallace A, Sayej WN. The IL 10/IL 5 ratio as potential tool for monitoring the inflammatory process in eosinophilic esophagitis. [poster presentation]; Pediatric Academic Society; 2017 May; San Francisco, CA.

10. Pressley-Wallace A, Sayej WN. The IL 10/IL 5 ratio as potential tool for monitoring the inflammatory process in eosinophilic esophagitis. [oral presentation] Eastern Society for Pediatric Research, 2017 March; Philadelphia, PA.

11. Wong J, Goodine S, Wang Z, Sayej WN. Efficacy of dietary therapy in children with eosinophilic esophagitis. [poster presentation] Eastern Society for Pediatric Research; 2017 March; Philadelphia, PA.

12. Jenson, Todd; Finck, Christine M.; Sayej, Wael N.; Foster, Christopher; Mitchell, Adam; Drinnan, Charles. Patient Specific Esophageal Epithelial Cells for Esophageal Tissue Engineering. 2016 World Congress of Pediatric Surgery; October 2016; Washington, DC

13. Sayej WN, Fernandez ML, Goodine S. Esophageal eosinophilia in pediatric patients with celiac disease resolves on a gluten free diet. [poster presentation] World Congress of Pediatric Gastroenterology, Hepatology and Nutrition; 2016 Oct; Montreal, Canada.

14. Sayej WN, Jensen T, Foster C, Fernandez M, Finck C. Characterization of cultured esophageal epithelial cells from pediatric patients with eosinophilic esophagitis. World Congress of Pediatric Gastroenterology, Hepatology and Nutrition; 2016 Oct; Montreal, Canada. [awarded: Poster of Distinction]

15. Loh K, Bezler NS, Emerick K, Sayej WN. A rare case of symptomatic hereditary hemochromatosis in a 5-year-old male. [poster presentation] World Congress of Pediatric Gastroenterology, Hepatology and Nutrition; 2016 Oct; Montreal, Canada.

16. Sayej WN, Fernandez ML, Alexander L, Ritter P, Zeiter D, Mohr F. A prospective, randomized, single blinded study to evaluate two different 1-day bowel preparation regimens in children ages 8- 21 years undergoing capsule endoscopy. [poster presentation] World Congress of Pediatric Gastroenterology, Hepatology and Nutrition; 2016 Oct; Montreal, Canada.

17. Jensen T, Pease M, Drinnan C, Mitchell A, Sayej WN, Finck C. Treatment of pediatric esophageal disease with a tissue engineered biomimetic construct. [oral presentation] TERMIS 4th World Congress; September 9-11, 2015; Boston, MA Page 13 of 15

18. Rana A, Lerer T, Fernandez M, Hyams J, Sylvester FA, Sayej W. Routine premedicaiton with intravenous methylprednisolone can prevent the need for dose intensification of infliximab in children with Crohn's disease. [poster presentation] NASPGHAN; 2015; Washington, DC.

19. Mokha J, Caimano M, Radolf J, Sayej W. Comparison of the gastric fluid microbiome of children with and without eosinophilic esophagitis. [poster presentation] NASPGHAN; 2015; Washington, DC. .

20. Samela K, Vance K, Chatfield B, Goodine S, Lerer T, Sayej WN. Give SFED a chance. [poster presentation] NASPGHAN; 2015; Washington, DC.

21. Fable J, Fernandez M, Lerer T, Sayej WN. Comparison of oral topical corticosteroids in pediatric patients with eosinophilic esophagitis. [poster presentation] NASPGHAN; 2015; Washington, DC.

22. Semancik E, Sayej WN. Case series: peanut allergy oral immunotherapy inducing eosinophilic esophagitis. [poster presentation] NASPGHAN; 2015; Washington, DC.

23. Grossi V, Bezler N, Finck C, Sayej W. A rare case of duodenal ulcer in an adolescent male. [poster presentation] NASPGHAN; 2015; Washington, DC.

24. Alkhouri R, Bahia G, Sayej W. The outcome of medical management with IV antibiotics of intra­ abdominal abscesses in children with Crohn's disease. [poster presentation] NASPGHAN; 2014; Atlanta, GA

25. Maharjan A, Sayej WN, Menoret A, Fernandez ML, Sylvester FA, Hyams JS, Vella AT. Biological assay to characterize esophageal lavage fluid from children with eosinophilic esophagitis. [poster presentation] NASPGHAN; 2014; Atlanta, GA

26. Sayej WN, Fernandez ML, Sylvester FA, Hyams JS, Vella AT, Menoret AT-lymphocyte isolation and phenotyping from esophageal biopsies in children with eosinophilic esophagitis: pilot study. [poster presentation] DOW; 2013; Orlando, FL.

27. Menoret A, Fernandez M, Sylvester FA, Hyams JS, Vella AT, Sayej WN. Proteomic mining of esophageal lavage from children with eosinophilic esophagitis. [poster presentation] DOW; 2013; Orlando, FL.

28. Francisco A Sylvester*, Jeffrey S. Hyams, Wael N. Sayej, Bella Zeisler, Donna Zeiter, Karan Emerick, Marina Fernandez; "A 12-hour bowel prep with polyethylene glycol 3350 is effective, well tolerated and safe in children" Oral presentation presented by Dr. Sylvester at DOW; May 19-22, 2012; San Diego, CA

29. Candi Schaufler*, Trudy Lerer, Brendan T. Campbell, Richard Weiss, Jeffery L. Cohen, Donna Zeiter, Wael N. Sayej, Jeffrey S. Hyams; "Pre-operative lmmunosuppression is Not Associated with Increased Post-Operative Complications Following Colectomy in Children With Ulcerative Colitis" Oral presentation presented by C. Schaufler at DOW; May 7-1 ~, 2011; Chicago, IL: Control ID: 992899

30. J. Stumphy*, D. Morgan, L. White, D. Zeiter, W. Sayej, F. Sylvester, J. Hyams; "lnfliximab as primary therapy for Crohn's disease in children" [poster presentation] NASPGHAN Annual Meeting; October 21-24, 2011; New Orleans, LA Page 14 of 15

31. Raza A. Patel*, Susan S. Baker, Wael N. Sayej, Robert D. Baker; "Two cases of H. Pylori Negative Peptic Ulcer Disease leading to Gastric Outlet Obstruction" [poster presentation] NASPGHAN Annual Meeting; October 21-24, 2011; New Orleans, LA

32. Sayej WN, Knight PK Ill, Ye L, Baker RD, Baker SS. CXCL-10 is a potential marker for autoimmune hepatitis. JPGN: 49 Suppl 1: E?6; 2009. [poster presentation] NASPGHAN; 2009 Nov 12-14; National Harbor, MD.

33. Sayej W, Patel R, Baker R, Baker S. Terminal ileal disease and positive ASCA lgA and lgG may be predictors for development of phlegmons in children with Crohn's disease. JPGN: 49 Suppl 1: E62; 2009. [poster presentation] NASPGHAN; 2009 Nov 12-14; National Harbor, MD.

34. Baker SS, Faden H, Sayej WN, Patel R, Baker RD. Clostridium difficile infection in children undergoing colonoscopy. [poster presentation] DOW; 2009 May; Chicago, IL. [awarded Poster of Distinction]

35. Sayej W, Patel R, Baker R, Tron E, Baker S. Treatment with high dose proton pump inhibitors helps distinguish eosinophilic esophagitis from non-eosinophilic esophagitis. [poster presentation] NASPGHAN; 2008 Nov; San Diego, CA. [awarded Poster of Distinction]

36. Lightfoot T, et al, Baker S, Sayej W. lgG-RBC sensitization associated with serine proteases and an lgG autoantibody in a patient with ulcerative colitis. [poster presentation] American Association of Blood Banks (AABB) Annual Meeting and TXPO 2008; 2008 Oct 4-7; Montreal, QC.

37. Sayej W, Tron E, Baker R, Baker S. One-step percutaneous endoscopic gastrojejunostomy tube placement, a new technique for gastroenterologists: case report of 3 patients. [poster presentation] NASPGHAN; 2007 Nov; Salt Lake City, UT.

38. Sayej W, Tron E, Baker R, Baker S. Endoclipping of gastrocutaneous fistula in a 7-year-old girl after removal of gastrostomy tube: case report. [poster presentation] NASPGHAN; 2007 Nov; Salt Lake City, UT.

39. Vitale E, Yildirim-Tourner C, Subramanian K, Sayej W, Schwalb MN, Cook S. Candidate gene analysis for multiple sclerosis on 12p12 in a large North American pedigree. Eur J Hum Genet. 2003 May; 11 Suppl 1: 236.

Abstracts without Named Authorship Role: Participated in collecting data on our residents and fellows' Entrustable Professional Activities (EPA's) Page 15 of 15

1. Mink RB, Carraccio CL, Herman BE, Weiss P, Turner DA, Stafford DE, Hsu DC, High PC, Fussell JJ, Curran ML, Chess PR, Schwartz A for SPIN. The link between milestone levels and fellow entrustment for the common pediatric subspecialty entrustable professional activities. [oral and poster presentation] Annual education meeting, Accreditation Council for Graduate Medical Education; 2016 Feb; National Harbor, MD.

2. Mink RB, Schwartz A, Herman BE; Turner DA, Myers AL, Kesselheim JC, Hsu DC, Curran ML, Carraccio CL for SPIN. Reliability and validity of a supervision scale for the common pediatric subspecialty entrustable professional activities. [poster presentation] Annual education meeting, Accreditation Council for Graduate Medical Education; 2016 Feb; National Harbor, MD.

3. Mink RB, Carraccio CL, Schwartz A, Dammann CE, High PC, McGann KA, Herman BE for SPIN. Creation of a pediatric subspecialty educational research network. [poster presentation] Annual spring meeting, Association of Pediatric Program Directors; 2016 April; New Orleans, LA.

4. Mink RB, Schwartz A, Herman BE, Curran ML, Hsu DC, Kesselheim JC, Myers AL, Turner DA, Carraccio CL. Creation and validation of entrustment scales for the common pediatric subspecialty entrustable professional activitles (EPAs). [oral presentation] Annual spring meeting, Association of Pediatric Program Directors; 2016 April; New Orleans, LA.

5. Mink RB, Carraccio CL, Herman BE, Aye T, Baffa JM, Chess PR, Fussell JJ, Sauer CG, Stafford DE, Weiss P, Schwartz A for SPIN. Do fellowship program directors (FPD) and clinical competency committees (CCC) agree in fellow entrustment decisions? [poster presentation] Annual spring meeting, Association of Pediatric Program Directors; 2016 April; New Orleans, LA.

6. Mink RB, Carraccio CL, Schwartz A, Dammann CE, High P, Kesselheim JC, McGann K, Herman BE. Establishing a medical education research network for the pediatric subspecialties. [poster presentation] Annual spring meeting, Pediatric Academic Societies; 2016 May; Baltimore, MD.

7. Mink RB, Carraccio CL, Herman BE, Dammann C, Mahan J, Pitts S, Sauer CG, Schwartz A. Variability in fellow entrustment across the pediatric subspecialties for the common pediatric subspecialty entrustable professional activities (EPAs). [poster presentation] Annual spring meeting, Pediatric Academic Societies; 2016 May; Baltimore, MD.