TMED10 Polyclonal Antibody Catalog No: Tcba10491

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TMED10 Polyclonal Antibody Catalog No: tcba10491

Available Sizes

Size: 50ul

Size: 100ul

Size: 200ul

Specifications

Application: WB,IHC

Research Area: Cancer,Hippo pathway,Neuroscience,Developmental Biology,Neurodegeneration,

Species Reactivity: Human,Mouse,Rat

Host Species: Rabbit

Isotype: IgG

Form: Liquid

Storage Buffer: Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Recommended Dilution: WB 1:500 - 1:2000 IHC 1:50 - 1:200

Storage Instruction:

Store at -20℃. Avoid freeze / thaw cycles.

Alternative Names: p23;P24(DELTA);p24d1;S31I125;S31III125;Tmp-21-I;TMP21

SwissProt: P49755

Gene ID: 10972 (human);

Calculated Molecular Weight: 24kDa

Purification: Affinity purification

Cellular Location: Cell membrane,Cytoplasmic vesicle,Endoplasmic reticulum membrane,Endoplasmic reticulum-Golgi intermediate compartment membrane,Golgi apparatus,Melanosome,Single-pass type I membrane protein,cis-Golgi network membrane,secretory vesicle membrane,trans-Golgi

Product Description

This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex\'s gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer\'s disease. This gene has a pseudogene on chromosome 8.

Western blot analysis of extracts of various cell lines, using TMED10 antibody at Immunohistochemistry of paraffin-embedded rat kidney using TMED10 Antibody at 1:1000 dilution. dilution of 1:100 (40x lens). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.

Immunohistochemistry of paraffin-embedded human liver injury using TMED10 Immunohistochemistry of paraffin-embedded mouse brain using TMED10 Antibody Antibody at dilution of 1:100 (40x lens). at dilution of 1:100 (40x lens).

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