SPTBN1 Cat. No.: 19-552

SPTBN1 Antibody

Immunohistochemistry of paraffin-embedded human Immunohistochemistry of paraffin-embedded human colon using SNAIL antibody breast using SNAIL antibody (19-550) at dilution of 1:100 (40x lens). (19-550) at dilution of 1:100 (40x lens).

Immunofluorescence analysis of U2OS cells using SNAIL antibody (19-550) at dilution of 1:100. Blue: DAPI for nuclear staining.

Specifications

September 27, 2021 1 https://www.prosci-inc.com/sptbn1-antibody-19-552.html HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse

Recombinant fusion containing a sequence corresponding to amino acids IMMUNOGEN: 2100-2200 of human SPTBN1 (NP_003119.2).

TESTED APPLICATIONS: WB

APPLICATIONS: WB: ,1:1000 - 1:3000

POSITIVE CONTROL: 1) U-87MG

2) HeLa

3) Jurkat

4) LO2

5) 293T

6) Mouse brain

PREDICTED MOLECULAR Observed: 275kDa WEIGHT:

Properties

PURIFICATION: Affinity purification

CLONALITY: Polyclonal

ISOTYPE: IgG

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.

Additional Info

OFFICIAL SYMBOL: SPTBN1

ELF, HEL102, SPTB2, betaSpII, beta chain, non-erythrocytic 1, beta-G spectrin, beta-II spectrin, beta-fodrin, beta-spectrin 2, beta-spectrin II, beta-spectrin non- ALTERNATE NAMES: erythrocytic 1, embryonic liver beta-fodrin, epididymis luminal protein 102, fodrin beta chain, spectrin beta chain, brain 1, spectrin, non-erythroid beta chain 1

GENE ID: 6711

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

September 27, 2021 2 https://www.prosci-inc.com/sptbn1-antibody-19-552.html Spectrin is an crosslinking and molecular scaffold protein that links the plasma membrane to the actin , and functions in the determination of cell shape, arrangement of transmembrane , and organization of organelles. It is composed BACKGROUND: of two antiparallel dimers of alpha- and beta- subunits. This is one member of a family of beta-spectrin . The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.

ANTIBODIES FOR RESEARCH USE ONLY.

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September 27, 2021 3 https://www.prosci-inc.com/sptbn1-antibody-19-552.html