SPTBN1 Antibody Cat. No.: 19-552
SPTBN1 Antibody
Immunohistochemistry of paraffin-embedded human Immunohistochemistry of paraffin-embedded human colon using SNAIL antibody breast using SNAIL antibody (19-550) at dilution of 1:100 (40x lens). (19-550) at dilution of 1:100 (40x lens).
Immunofluorescence analysis of U2OS cells using SNAIL antibody (19-550) at dilution of 1:100. Blue: DAPI for nuclear staining.
Specifications
September 27, 2021 1 https://www.prosci-inc.com/sptbn1-antibody-19-552.html HOST SPECIES: Rabbit
SPECIES REACTIVITY: Human, Mouse
Recombinant fusion protein containing a sequence corresponding to amino acids IMMUNOGEN: 2100-2200 of human SPTBN1 (NP_003119.2).
TESTED APPLICATIONS: WB
APPLICATIONS: WB: ,1:1000 - 1:3000
POSITIVE CONTROL: 1) U-87MG
2) HeLa
3) Jurkat
4) LO2
5) 293T
6) Mouse brain
PREDICTED MOLECULAR Observed: 275kDa WEIGHT:
Properties
PURIFICATION: Affinity purification
CLONALITY: Polyclonal
ISOTYPE: IgG
CONJUGATE: Unconjugated
PHYSICAL STATE: Liquid
BUFFER: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
STORAGE CONDITIONS: Store at -20˚C. Avoid freeze / thaw cycles.
Additional Info
OFFICIAL SYMBOL: SPTBN1
ELF, HEL102, SPTB2, betaSpII, spectrin beta chain, non-erythrocytic 1, beta-G spectrin, beta-II spectrin, beta-fodrin, beta-spectrin 2, beta-spectrin II, beta-spectrin non- ALTERNATE NAMES: erythrocytic 1, embryonic liver beta-fodrin, epididymis luminal protein 102, fodrin beta chain, spectrin beta chain, brain 1, spectrin, non-erythroid beta chain 1
GENE ID: 6711
USER NOTE: Optimal dilutions for each application to be determined by the researcher.
Background and References
September 27, 2021 2 https://www.prosci-inc.com/sptbn1-antibody-19-552.html Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed BACKGROUND: of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene.
ANTIBODIES FOR RESEARCH USE ONLY.
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September 27, 2021 3 https://www.prosci-inc.com/sptbn1-antibody-19-552.html