Anti-CKMT1A Polyclonal Antibody Cat: K109096P Summary:

【Product name】: Anti-CKMT1A antibody 【Source】: Rabbit

【Isotype】: IgG 【Species reactivity】: Human Mouse Rat

【Swiss Prot】: P12532 【 ID】: 548596

【Calculated】: MW:47/50kDa 【Observed】: MW:47kDa

【Purification】: Affinity purification

【Tested applications】: WB IHC

【Recommended dilution】: WB 1:8000-12000. IHC 1:50-200.

【WB Positive sample】: Mouse heart,Rat heart

【IHC Positive sample】: Human breast cancer

【Subcellular location】: Cytoplasm Nucleus

【Immunogen】: Recombinant protein of human CKMT1A

【Storage】: Shipped at 4°C. Upon delivery aliquot and store at -20°C Background: Mitochondrial (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate . Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on have been identified which encode identical mitochondrial creatine kinase proteins.

Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information Verified picture

Western blot analysis with CKMT1A antibody Immunohistochemistry of paraffin-embedded diluted at 1:10000;Lane: Mouse heart,Rat heart Human breast cancer with CKMT1A antibody diluted at 1:100

Sales:[email protected] For research purposes only. Tech:[email protected] Please visit www.solarbio.com for a more product information