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Abstracts of the CEHN Conference: the Contributions of Epigenetics In CEHN Research Conference San Francisco, CA May 30–June 1, 2012 The Contribution of Epigenetics in Pediatric Environmental Health 2012 Children’s Environmental Health Network CEHN Research The Contribution of Conference Epigenetics in Pediatric San Francisco, CA Environmental Health May 30–June 1, 2012 TABLE of CONTENTS Keynote Presentations 10 Mechanisms 16 Placental Epigenetics and Infant 4 Developmental Stressors and Cynthia Bearer, moderator Neurobehavior Epigenetics Carmen J. Marsit, Cailey Bromer, James F. Dana Dolinoy 10 Epigenetic Regulation after Padbury, Barry M. Lester 4 Embryo Vulnerability in An Always Environmental Intervention 17 Methylation Levels at Imprinting Changing World: Epigenetics and Stephanie Lovinsky-Desir, R. Ridder, D. Torone, Control Regions Are Not Altered with H. Jiang, S. Narula, M. Kattan, E. DiMango, Fertility Treatments Beyond R.L. Miller David Epel R.C. Rancourt, H.R. Harris, K.B. Michels 11 Epigenetic Changes in IFN-gamma 5 Developmental Origins of Health and 17 A Genomic & Epigenomic Integration and FoxP3 due to SHS Approach on Obesity Disease (DOHaD)—New Insights and Arunima Kohli, Marco Garcia, Olivier Humblet, Opportunities Shaoyong Su, Haidong Zhu, Harold Snieder, John Balmes, Katharine Hammond, Ira Tager, Yanbin Dong, Frank Treiber, Bernard Gutin, Mark A. Hanson Kari Nadeau Gregory Harshfield, Xiaoling Wang 5 Epigenetics: A Biological Database for 11 The Role of PBRM1 in Malignant “Personalized Medicine” Rhabdoid Tumor Development 18 Critical Windows of Early Robert H. Lane Darmood Wei, Yasumichi Kuwahara, Bernard E. Weissman Exposure & Sensitivity II 6 Effects of Prenatal Environmental Richard Finnell, moderator Exposures on Child Health and 12 Choline Prevents Ethanol Inhibition of Development Neurite Outgrowth 18 Epigenetic Marks of Impaired Glucose Frederica P. Perera Ningfeng Tang, Penny Bamford, Min He, Cynthia Tolerance in Pregnancy Bearer Adrienne S. Ettinger, Andrea Baccarelli,Letizia Mini-Symposiums Tarantini, Benedetta Albetti, Robert O. Wright 13 Environmental Epigenetics: 19 DNA Methylation of 11βHSD2 Abstracts From Mice to Humans Correlates with Infant Growth Nina Holland, moderator Carolyn E. Banister, James F. Padbury, Carmen 8 Biomarkers J. Marsit, Martyn Smith, moderator 13 miRNA Profiles Following Air Pollutant 19 Birth Defects as Clues to the Etiology Human Exposures of Cancer in Children 8 Epigenetics and Environment Juliette J. Kahle, Kelly E. Duncan, Michael T. Robert O. Wright, Andrea Baccarelli, Rosalind Paul Fisher, Peggy Reynolds, Julie Von Behren, Schmitt, Beena Vallanat, Anna Astriab Fisher, Suzan Carmichael, Sonja Rasmussen, Gary Shaw Wright Robert B. Devlin, David Diaz-Sanchez 20 The Effects of Prenatal Alcohol 8 Effects of Maternal Lead Exposure on 13 Prenatal BPA: Epigenetic Disruption, Exposure on Choline Metabolism: How DNA Methylation in Children Brain, and Behavior Epigenetic Mechanisms May Mediate Douglas M. Ruden, Arko Sen, Robert O. Wright Marija Kundakovic, Kathryn Gudsnuk, Frederica P. Perera, Rachel L. Miller, Frances A. Champagne Alcohol’s Teratogenic Effects 8 Epigenetic Effects of Air Pollution and Tanya T. Nguyen, Carl L. Keen, Christina D. Endocrine-Disrupting Chemicals— 14 PAH Linked Aberrant DNA Methylation Chambers, Jennifer D. Thomas Methods and Results from Human of Asthma Genes in Sensitized Mice Research Xiang Zhang, Hanjie Zhang, Sophie Chu, Rachel 20 Session I: The Association Andrea Baccarelli Miller, Shukmei Ho between Epigenetics and 15 Effects of Age, Sex, and Prenatal Pediatric Disease 9 The Role of Nutrition and Exposure on Methylation Rachel Miller, moderator Epigenetics in Human Health Nina Holland, Paul Yousefi, Raul Aguilar, Vitaly Volberg, Hong Quach, Karen Huen, Asa Dana Dolinoy, moderator Bradman, Lisa Barcellos, Brenda Eskenazi 20 Epigenetics in Epidemiologic Research Cathrine Hoyo, Amy Murtha, Joellen Schildkraut, 9 Epigenetic Effects of Choline During Susan Murphy 16 Critical Windows of Early Brain Development 21 Neonatal Epigenetic Signatures Steven Zeisel Exposure & Sensitivity I of Asthma and Asthma-Protective 9 Influence of Prenatal Arsenic Robert O. Wright, moderator Exposures Exposure, Folate Nutritional Status, Donata Vercelli 16 DNA Methylation Signatures and IL10 and Newborn Sex on Cord Blood DNA Levels in Childhood ALL 21 DNA Methylation Patterns in Siblings Methylation Adam J. de Smith, Seung-Tae Lee, Yuanyuan with and without Asthma Mary V. Gamble Xiao, Ling-i Hsu, Kyle M. Walsh, Jianqiao Xiao, David A. Schwartz 10 Folate Depletion Alters Fetal Hepatic Helen M. Hansen, Anand P. Chokkalingam, DNA Methylation Catherine Metayer, Patricia A. Buffler, Joseph L. Jill McKay Wiemels 22 Session II: The Association 28 EDCs and Childhood Obesity— 35 In Utero Smoke Exposure and Pediatric between Epigenetics and Exposure Assessment Asthma Marijke de Cock, Yolanda G.H. Maas, Margot Sam S. Oh, Haig Tcheurekdjian, Lindsey A. Roth, Pediatric Exposures van de Bor Elizabeth A. Nguyen, Saunak Sen, Joshua M. Cynthia Bearer, moderator Galanter, Adam Davis, Harold J. Farber, Frank D. 29 Prenatal Folic Acid Supplements and Gilliland, Rajesh Kumar, Pedro C. Avila, Emerita 22 Maternal Tobacco Exposure Is Infant Bronchiolitis Brigino-Buenaventura, Rocio Chapela, Jean G. Associated With Alterations In Stacy Dorris, Frances Tylavsky, Tebeb Ford, Michael A. LeNoir, Fred Lurmann, Kelley Gebretsadik, Tina Hartert, Ed Mitchel, Terryl Meade, Denise Serebrisky, Shannon Thyne, Placental DNA Methylation and Gene Hartman, Kecia Carroll Expression William Rodriguez-Cintron, Jose R. Rodriguez- Melissa A. Suter, Jun Ma, R. Alan Harris, Lauren 29 Perinatal Phthalate Exposure and the Santana, L. Keoki Williams, Luisa N. Borrell, Patterson, Cindy Shope, Lori Showalter, Adi Developing Brain Esteban G. Burchard Abramovici, Kjersti Aagaard Sarah F. Evans, Patrizia Casaccia 36 Role of Epigenetics in Child and 22 DNA Methylation during Development 30 Possible Epigenetic Mechanisms Adolescent Mental Health and Alteration by Alcohol Exposure of Developmental Toxicity from Chidinma Okoronkwo, Chijioke Isinguzo Feng C. Zhou Organohalogen Flame Retardants 36 The Epigenetic Effects of Human Milk 23 Behavioral Experience Determines Pb Rebecca Fuoco, Melissa Cline, Arlene Blum on Obesity and Stress Effects 30 Ambient Air Toxics and Preterm Birth Heide S. Temples Deborah A. Cory-Slechta, Doug Weston, Sue Liu, Jo Kay C. Ghosh, Michelle Wilhelm, Jason Su, 37 Family-Based Association Study of Kian Merchant-Borna, Joshua L. Allen, David W. Myles Cockburn, Onyebuchi A. Arah, Michael ADHD and Genes Increasing the Risk Anderson, Jay S. Schneider Jerrett, Beate Ritz for Smoking Behaviors 31 Ethical Implications of Epigenetics Geeta A. Thakur, Sarojini M. Sengupta, Natalie Poster Presentation Steven G. Gilbert Grizenko, Zia Choudhry, Ridha Joober 31 Folate Protection of Embryogenesis 37 Low Birth Weight and The Metabolic Abstracts and Gene Expression Syndrome in Young Adults: Evidence 25 Role of Mercury in the Alteration of Mingda Han, Lifeng Zhang, Kersti K. Linask from The Butantã Cohort Global DNA Methylation 32 Quality Assessment Tools in Published Maria Helena Valente, Ana Maria de Ulhôa Thomas Achankunju, Michael Carvan III Escobar, Filumena Maria da Silva Gomes, Animal Studies Alexandra Brentani, Sandra J.F.E. Grisi 25 Ventilation Affects Histone Marks in David Krauth, Tracey Woodruff, Lisa Bero Lung and Brain of Preterm Lambs 32 Mother’s Age at DDT Exposure Kurt Albertine, Jeremy Alvord, Brady Houston, Matthew McCoy, Li Dong, Mar Janna Dahl, Modifies Infant Birth Weight Christopher Callaway, Robert McKnight, Donald Nickilou Y. Krigbaum, Piera M. Cirillo, Pam Null, Bradley Yoder, Robert DiGeronimo, Robert Factor-Litvak, Barbara A. Cohn Lane 33 DNA Methylation in Childhood 26 Global Methylation as a Biomarker of B-Lymphoblastic Leukemias Diesel Exhaust Seung-Tae Lee, Yuanyuan Xiao, Marcus Muench, Kelly J. Brunst, Yuet-Kin Leung, Patrick H. Ryan, Marina E. Fomin, Jianqiao Xiao, Ivan Smirnov, Gurjit K. Khurana Hershey, Grace K. LeMasters, Anand Chokalingam, Catherine Metayer, Shuk-Mei Ho Patricia Buffler, Joseph Wiemels 27 Endocrine Disrupters and Obstetric 33 Exposure & Fetal Growth Dysregulates Complications in a Cohort of Placental miRNA Matthew A. Maccani, James F. Padbury, Valerie Massachusetts Women S. Knopik, Carmen J. Marsit Brittany M. Charlton, Jenny Carwile, Holly R. Harris, Thomas F. McElrath, Louise Wilkins-Haug, 34 Placental 11β-HSD2and Birth Weight in Karin B. Michels Hamilton County, TN 27 Indian Children’s Exposure to Colleen Mikelson, Margaret Kovach, David Adair, Steve Symes, Sean Richards Poisonous Substances: Prospective Assessment of Patterns, Severity, and 34 Epigenetics of Wood Smoke Exposure Clinical Outcome and Diet in Child Asthma Shobha Churi, M. Ramesh, Krunal Bhakta, Jacob Luke Montrose, Blakely Brown, Elizabeth Chris Putnam, Tony J. Ward, Curtis W. Noonan 28 Type 2 Diabetes in Belize: Education & Analysis Jena Daniels, Shelley Brown, Anna Monahan CEHN Keynote Presentations Developmental Stressors and Embryo Vulnerability in An Always Epigenetics Changing World: Epigenetics and Dana Dolinoy Beyond Searle Assistant Professorship in Public Health, University of Michigan David Epel School of Public Health Jane & Marshall Steel Jr. Professor Emeritus in Marine Sciences, Cell and Environmental exposures during early development Developmental Biology, Stanford University and other critical life stages may induce changes to the epigenome resulting in potentially deleterious phenotypic Studies on regulation/homeostasis/stress responses
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