Christy Haynes University of Minnesota

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Christy Haynes University of Minnesota Christy Haynes is the Elmore H. Northey Professor of Chemistry and a Distinguished McKnight University Professor at the University of Minnesota where she leads the Haynes Research Group, a lab dedicated to applying analytical and nanomaterials chemistry in the context of biomedicine, ecology, and toxicology. Professor Haynes completed her undergraduate work at Macalester College in 1998 and earned a Ph.D. in chemistry at Northwestern University in 2003 under the direction of Richard P. Van Duyne. Before joining the faculty at the University of Minnesota in 2005, Haynes performed postdoctoral research in the laboratory of R. Mark Wightman at the University of North Carolina, Chapel Hill. Among many honors, she has been recognized as an Alfred P. Sloan Fellow, a Searle Scholar, a Dreyfus Teacher-Scholar, and a National Institutes of Health "New Innovator." In addition to wide recognition for her research contributions, including over 175 peer-review publications, she has been recognized by her university as an Outstanding Postdoctoral Mentor and the Sara Evans Faculty Woman Scholar/Leader Award. Professor Haynes is currently the Associate Head of the University of Minnesota Department of Chemistry, the Associate Director of the National Science Foundation- funded Center for Sustainable Nanotechnology, and an Associate Editor for the journal Analytical Chemistry. Optimized carbon dots: green imaging agents at the nano-bio interface Polymerized nanoscale carbon dots hold great potential for a variety of applications based on their excellent optical properties and ease of synthesis from benign precursors; however, the mechanism behind the high quantum yield luminescence is still under debate. Via systematic choice of carbon dot precursors and careful separation methods, a size series of carbon dots show tunable luminescence as well as capacity to enable super-resolution imaging in live cells. Nuclear magnetic resonance and complimentary characterization methods coupled with computational models reveal the potential molecular underpinnings of the carbon dot optical properties, presenting the possibility for enhanced design of new carbon dots nanostructures. .

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Engineered Nanomaterial Interactions with Bacterial Cells A DISSERTATION SUBMITTED TO THE FACULTY OF THE GRADUATE SCOOL OF THE UNIVERSITY OF MINNESOTA BY Ian Lyle Gunsolus IN PARTIAL FULFILLMENT OF THE REQUIREMENTS FOR THE DEGREE OF DOCTOR OF PHILOSOPHY Christy L. Haynes, Advisor May, 2016 © Ian Lyle Gunsolus 2016 Acknowledgements This dissertation is the product of many collaborations, small and large, professional and personal. Here I would like to acknowledge the generous support of all my collaborators, including professors, colleagues, friends, and family; without their support, this dissertation would not exist. First, I would like to thank my advisor, Prof. Christy Haynes, for building a research environment that helped me grow from a classroom student of chemistry to an independent researcher. By encouraging me to think beyond my independent work and actively engage with the broader scientific community, Christy has made me into a better scientist, and I thank her for it. I would also like to thank Prof. Philippe Bühlmann for his insightful contributions to my research throughout my thesis work. Through his service on my preliminary exam and thesis committees and his role as co-principal investigator (along with Christy) on research assessing the enviornmental behavior of silver nanoparticles, Phil has sharpened the focus of my research and deepened my critical analysis of chemical phenomena. My involvement in the Center for Sustainable Nanotechnology (CSN) has been a highlight of my graduate studies, and I am greatful to all past and present CSN members. I would particularly like to thank Prof. Robert Hamers, whose example of leadership through dedicated service amazes and inspires me; Prof.
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Christy Haynes Chemistry Finkenstaedt-Quinn, Solaire A., Shencheng Ge, and Christy L. Haynes. 2015. Cytoskeleton Dynamics in Drug-Treated Platelets
Christy Haynes Chemistry Finkenstaedt-Quinn, Solaire A., Shencheng Ge, and Christy L. Haynes. 2015. Cytoskeleton dynamics in drug-treated platelets. Analytical and Bioanalytical Chemistry (FEB 21), 10.1007/s00216-015-8523-7. Koseoglu, Secil, Audrey F. Meyer, Donghyuk Kim, Ben M. Meyer, Yiwen Wang, Joseph J. Dalluge, and Christy L. Haynes. 2015. Analytical characterization of the role of phospholipids in platelet adhesion and secretion. Analytical Chemistry 87, (1) (JAN 06), 10.1021/ac502293p. Chan, John D., Prince N. Agbedanu, Mostafa Zamanian, Sarah M. Gruba, Christy L. Haynes, Timothy A. Day, and Jonathan S. Marchant. 2014. 'Death and axes': Unexpected Ca2+ entry phenologs predict new anti-schistosomal agents. PLoS Pathogens 10, (2) (JAN 01), 10.1371/journal.ppat.1003942. Cherukulappurath, Sudhir, Si Hoon Lee, Antonio Campos, Christy L. Haynes, and Sang- Hyun Oh. 2014. Rapid and sensitive in situ SERS detection using dielectrophoresis. Chemistry of Materials 26 (7) (APR 08): 2445-52. Gruba, Sarah M., Audrey F. Meyer, Benjamin M. Manning, Yiwen Wang, John W. Thompson, Joseph J. Dalluge, and Christy L. Haynes. 2014. Time- and concentration- dependent effects of exogenous serotonin and inflammatory cytokines on mast cell function. ACS Chemical Biology 9, (2) (FEB 21), 10.1021/cb400787s. Gunsolus, Ian L., Dehong Hu, Cosmin Mihai, Samuel E. Lohse, Chang-Soo Lee, Marco D. Torelli, Robert J. Hamers, Catherine J. Murhpy, Galya Orr, and Christy L. Haynes. 2014. Facile method to stain the bacterial cell surface for super-resolution fluorescence microscopy. Analyst 139 (12) (JUN 21): 3174-8. Haynes, Christy L. 2014. Editorial-analytical toxicology of nanoparticles. The Analyst 139, (5) (JAN 01), 10.1039/c3an90114a.
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Diverse, Multi-Disciplinary Collaboratives Key to Successful
DECEMBER 2014 CHEM news DEPARTMENT OF CHEMISTRY NEWSLETTER Inside this issue… Diverse, multi-disciplinary collaboratives key to If today’s researchers Instrumentation 3 are going to successfully Facility successful research tackle some of society’s most complex and 10National Historic important human Chemical Landmark health, energy and Celebration environmental problems, they need to draw on diverse expertise by Student Honors 12 collaborating with other university researchers Long-Time Employees and leading industrial 16 partners. Professor Erin Carlson explains her research during the departmental tours for the National Historic Chemical Landmark celebration in September. Promotions 18 Researchers in the Department of Chemistry Critical to the success of the centers is the unique have recently been extraordinarily successful in collegial and highly collaborative culture and obtaining national funding for such collabora- climate fostered in the College of Science & Faculty & Staff Honors tions through the establishment of major research Engineering (CSE), which supports and facilitates 20 centers. departments working and growing together. “Some of the very best science is done when Over the past two years, Department of Chemistry Donors researchers with diverse backgrounds and perspec- researchers have received more than $63 million 22 tives work together to tackle the most challenging from the Department of Energy (DOE) and problems,” said Professor William Tolman, chair National Science Foundation (NSF) for major re- of the Department of Chemistry. search centers that involve University of Minnesota continued on page 6 message from the CHAIR CHEM news Building upon our history DECEMBER 2014 We stand on the shoulders of others DEPARTMENT OF CHEMISTRY CHAIR in our work, dreams, and aspirations, William Tolman and sometimes it’s important to EDITOR Eileen Harvala recognize this in a way that is both Department of Chemistry fitting and inspirational.
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Biography: Christy Haynes Is the Elmore H. Northey Professor of Chemistry and a Distinguished Mcknight University Professor at T
Biography: Christy Haynes is the Elmore H. Northey Professor of Chemistry and a Distinguished McKnight University Professor at the University of Minnesota where she leads the Haynes Research Group, a lab dedicated to applying analytical and nanomaterials chemistry in the context of biomedicine, ecology, and toxicology. Professor Haynes completed her undergraduate work at Macalester College in 1998 and earned a Ph.D. in chemistry at Northwestern University in 2003 under the direction of Richard P. Van Duyne. Before joining the faculty at the University of Minnesota in 2005, Haynes performed postdoctoral research in the laboratory of R. Mark Wightman at the University of North Carolina, Chapel Hill. Among many honors, she has been recognized as an Alfred P. Sloan Fellow, a Searle Scholar, a Dreyfus Teacher-Scholar, and a National Institutes of Health "New Innovator." In addition to wide recognition for her research contributions, including over 180 peer-review publications, she has been recognized by her university as an Outstanding Postdoctoral Mentor and the Sara Evans Faculty Woman Scholar/Leader Award. Professor Haynes is currently the Associate Head of the University of Minnesota Department of Chemistry, the Associate Director of the National Science Foundation- funded Center for Sustainable Nanotechnology, and an Associate Editor for the journal Analytical Chemistry. Abstract: Engineered nanoparticles are increasingly being incorporated into devices and products across a variety of commercial sectors – this means that engineered nanoscale materials will either intentionally or unintentionally be released into the ecosystem. The long-term goal of the presented work is to understand the molecular design rules that control nanoparticle toxicity using aspects of materials science (nanoparticle design, fabrication, and modification), analytical chemistry (developing new assays to monitor nanotoxicity), and ecology (monitoring how nanoparticles enter and accumulate in the food web through bacteria and how these nanoparticles influence bacterial function).
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