An online version of this diagram is available at BioCyc.org. Biosynthet on the right, and reactions not assigned to any pathway are in the far r Periplasmic (where appropriate) and extracellular reactions and proteins Gcf_900520325Cyc: Escherichia coli isolate Escherichia coli str. TO60 genome assembly Cellular Overview Connections between pathways are omitted for legibility.

sn-glycerol glutamate a dicarboxylate an amino putrescine glutathione thiosulfate a hexose 6- succinate L-ascorbate 3-phosphate agmatine asp glutamate acid a dipeptide a dipeptide a dipeptide poly-β-1,6- thr β β O-acetyl-L-serine O-acetyl-L-serine spermidine putrescine cys sulfate sulfate arg Fe 3+ Fe 3+ phosphate an amino an aromatic an aromatic a dipeptide 1-( -D 1-( -D 3-(3- phosphate asp yersiniabactin N-acetyl-D- ammonium L-homoserine thiamine cys cys spermidine spermidine citrate sn-glycerol xanthosine phosphate phosphate arg phosphate protoheme an amino acid an amino an amino an amino an amino S-methyl-L- a tripeptide a tripeptide a tripeptide amino acid amino acid ribofuranosyl) ribofuranosyl) (R)- putrescine 2,3-dioxo- 2,3-dioxo- 2,3-dioxo- molybdate arg phosphate enterobactin a hydroxamate 3+ 3+ shikimate hydroxyphenyl) 3-phenylpropanoate putrescine ammonium sulfate sulfate sulfate Fe Fe phosphate acid acid acid acid acid (S)-lactate methionine glucosamine a dipeptide nicotinamide nicotinamide pantothenate diphosphate spermidine L-gulonate L-gulonate L-gulonate 3-phosphate predicted propanoate sulfate Fe 2+ Fe 3+ predicted predicted ATP-driven predicted predicted predicted predicted predicted predicted predicted predicted predicted predicted predicted ABC PEP-driven transporter ABC ABC ABC ABC ABC ABC ATP-driven ABC ABC ABC predicted ABC ABC RS12175 RS20200 RS17215 RS25975 RS16655 RS09470 RS23070 RS16965 RS02335 RS20415 RS06355 RS11935 RS16450 transporter RS11770 RS11775 RS17690 transporter RS00670 RS00665 RS00660 RS07900 of sn- RS18850 RS06545 RS07110 transporter RS09005 transporter RS18415 RS04650 transporter RS23825 RS23920 transporter RS07070 RS01170 RS00165 RS22665 RS04695 transporter RS23290 RS17785 RS19940 RS17795 transporter transporter RS21635 RS03710 RS01500 transporter transporter RS22885 RS08085 RS24535 RS00950 RS03205 RS11740 RS18225 RS09860 transporter RS00545 transporter of RS25815 RS22550 RS01150 RS11590 RS14930 transporter of spermidine/ of L- glycerol 3- of putrescine of L-cysteine/ of sulfate/ of sulfate of L-arginine of Fe3+ of Fe3+ of phosphate of glutamate/ of an yersiniabactin of a dipeptide putrescine ascorbate phosphate glutathione thiosulfate L-aspartate amino acid poly-β-1,6- O-acetyl-L-serine O-acetyl-L-serine an aromatic an aromatic ammonium thr 1-(β-D 1-(β-D (R)- putrescine spermidine spermidine 2,3-dioxo- 2,3-dioxo- 2,3-dioxo- 3-(3- molybdate phosphate enterobactin a hydroxamate phosphate protoheme N-acetyl-D- shikimate thiamine citrate sn-glycerol 3-phenylpropanoate putrescine ammonium sulfate sulfate sulfate Fe 3+ Fe 3+ an amino an amino an amino an amino an amino an amino (S)-lactate S-methyl-L- a tripeptide a tripeptide a tripeptide a dipeptide L-homoserine ribofuranosyl) cys cys phosphate arg phosphate 2+ 3+ phosphate asp amino acid amino acid ribofuranosyl) pantothenate diphosphate spermidine L-gulonate L-gulonate L-gulonate hydroxyphenyl) xanthosine sulfate a hexose 6- arg Fe Fe glucosamine 3-phosphate acid acid acid acid acid acid yersiniabactin methionine nicotinamide nicotinamide succinate L-ascorbate propanoate agmatine Fe 3+ 3+ glutamate a dipeptide a dipeptide a dipeptide a dipeptide putrescine putrescine glutathione thiosulfate sulfate phosphate arg Fe phosphate glutamate an amino 6-phosphate sn-glycerol a dicarboxylate spermidine cys sulfate acid 3-phosphate asp

Cofactor, Carrier, and Vitamin Biosynthesis Nucleoside and Nucleotide Degradation Fatty Acid and Lipid Biosynthesis Cofactor, Prosthetic Group, Electron Carrier Degradation Degradation/ α 6 β Utilization/ an inactive 4-amino-4- -Kdo-(2->4)- a [protein]- an O - a nascent 3-hydroxy-5- peptidoglycan D- poly- -1,6- a holo-[EntF biotin biosynthesis I a reduced adenosylcobinamide a purine α acetate a [glutamine- H O an L-asparaginyl- superpathway of pyrimidine ribonucleoside SAM deoxy-α-L- -Kdo-(2->6)- methylguanine peptidoglycan L-cystathionine 2 N-acetyl-D- L-seryl-carrier ser superpathway of ubiquinol- [2Fe-2S] iron-sulfur superpathway of menaquinol-8 biosynthesis I superpathway of tetrahydrofolate biosynthesis and salvage superpathway of tetrahydrofolate biosynthesis lipoate flavin biosynthesis I (bacteria and plants) thiamine diphosphate 2-carboxy-1,4- prenylated FMNH glutathione-peroxide molybdenum cofactor biosynthesis L-cysteine biosynthesis demethylmenaquinol- superpathway of fatty acids biosynthesis (E. coli) Fermentation mixed acid fermentation purine nucleotides degradation II (aerobic) Assimilation - Other L-cysteine oxohexanoyl-CoA alanyl-DAP crosslink ATP ATP Asn lipoate biosynthesis 5-methoxy-6-methylbenzimidazolyl 2 superpathway of thiamine diphosphate biosynthesis I superpathway of lipopolysaccharide biosynthesis superpathway of pyrimidine pseudouridine degradation uracil degradation III UTP and CTP dephosphorylation I heme degradation V flavodoxin ribonucleoside synthetase]- [tRNA ] superpathway of demethylmenaquinol-8 biosynthesis I salvage I VI (from L-methionine) 8 biosynthesis I phosphatidylglycerol phosphatidylglycerol deoxyribonucleosides degradation superpathway of purine deoxyribonucleosides degradation heme triphosphate arabinopyranosyl lipid IV (E. coli) in DNA (meso-DAP glucosamine protein] 8 biosynthesis (prokaryotic) cluster biosynthesis biosynthesis naphthoquinol biosynthesis adenosylcobamide biosynthesis biosynthesis redox reactions A met RS19710 met and incorporation II biosynthesis I (plastidic) ribonucleosides degradation acetoacetate reductase 5'-triphosphate L-tyrosine II (Bacillus) all-trans- a (3R)-3- biosynthesis II (non-plastidic) 2'-deoxycytidine degradation IV ditrans,octacis containing) a malonyl-[acp] chorismate from adenosylcobinamide-GDP acetyl-CoA phosphoenolpyruvate pseudouridine uracil UTP degradation acetate CoA- bifunctional murein (R)-lipoate chorismate prenol GSSG cys ATP 1,4-dihydroxy- cytidine protoheme -undecaprenyl bifunctional cystathionine poly-beta-1,6- malonyl-ACP O- IPP L-cysteine desulfurase chorismate GTP GTP octanoate GTP 5-methoxy-6- DMAPP cys met octaprenyl hydroxytetradecanoyl- UDP-N-acetyl- AMP (to acetyl CoA) transferase ATPase aminoacyl-tRNA enterobactin lipoate-- HMP-PP DHAP DHAP 2'-deoxyguanosine cytidine pseudouridine kinase: protoheme bifunctional phosphate DNA-binding DD-endopeptidase/ bifunctional [glutamate- methyltransferase isochorismate lipoate-- isochorismate methylbenzimidazole methionine 2-naphthoate diphosphate acetyl-CoA [acp] α-D-glucosamine cytidine pyrimidine utilization nucleoside anaerobic membrane-bound beta-lyase: metC RavA: ravA N-acetyl-D- hydrolase: synthase thiamine nicotinate-nucleotide-- NAD(P)H- NAD(P)H- pyruvate kinase: pyk deaminase: cdd ECTO60_RS08255 CTP synthase acetoacetate adenosylcobinamide subunit murein LD- met RS22490 met BioC: bioC isopentenyl- cysteine synthase isochorismate protein synthase cysteine adenosyltransferase: carboxylase phosphoenolpyruvate deaminase: ribonucleoside- transcriptional lytic murein -ammonia ligase]- nucleoside glucosamine ECTO60_RS13635 subunit a malonyl-[acp] GTP GTP protein phosphate dimethylbenzimidazole isopentenol cysteine molybdopterin- 2'-deoxyadenosine 5'/3'- uridine pseudouridine protein A: rutA (glutamine triphosphatase anaerobilin synthase: acetoacetyl-CoA kinase/ alpha: atoD carboxypeptidase: bifunctional diphosphate EntC: entC synthase ligase GTP cyclohydrolase EntC: entC desulfurase metK 1,4-dihydroxy- acyl-ACP--UDP-N- dependent dependent pyruvate kinase I: carboxylase: cdd triphosphate regulator/O6- adenylyl-L-tyrosine N-deacetylase EntD: entD desulfurase cyclohydrolase cyclohydrolase ligase synthase: kinase: thiM glutathione- desulfurase synthase GTP carboxyl thymidine nucleotidase 5'-phosphate hydrolyzing) NudI: nudI ECTO60_RS01080 adenosylcobinamide- lipid IV(A) 4- transglycosylase mepS maltose regulon triphosphatase aminoacyl-tRNA methyl ester LplA: lplA II: ribA phosphoribosyltransferase: glutathione D-ribulose 5-phosphate glycerol-3- glycerol-3- ECTO60_RS23625 3+ transferase: methylguanine-DNA acetate CoA- Delta-isomerase: CsdA: csdA isochorismate EntC: entC LplA: lplA isochorismate CsdA: csdA SAM 2-naphthoate transferase acetylglucosamine O- ECTO60_RS11370 pyrimidine/purine Fe reductase- amino-4-deoxy-L- EmtA: emtA phosphorylase/ NudI: nudI PgaB: pgaB I FolE: folE I FolE: folE a [lipoyl-carrier thiE disulfide CsdA: csdA adenylyltransferase pyrimidine/purine SurE: surE 5 : pyrG phosphate transcriptional hydrolase: enterobactin beta-ketoacyl- (lipoyl)adenylate 5-methoxy-6-cobT peroxidase: polyprenyltransferase: phosphate phosphate FMN-N -oxide (Z)-3-ureidoacrylate ECTO60_RS07980 methyltransferase transferase YdiF: murein DD- [glutamate-- ECTO60_RS04860 synthase isochorismate 7,8- 7,8- 6 2,5-diamino-6-(5-phospho-D- thiamine synthase [+ 2 isozymes] subunit acyltransferase: lpxA 2'-deoxyuridine pyrimidine/purine nucleoside pseudouridine- activating arabinosyltransferase: predicted IscS subfamily protein] N - reductase: [+ 2 isozymes] MoeB: moeB GTP 3',8- adenosine nucleoside [+ 4 isozymes] UDP 2+ acetoacetyl-CoA guanylyltransferase: [+ 5 isozymes] repressor/ ECTO60_RS19740 non-ribosomal ACP synthase methylbenzimidazole ECTO60_RS11195 an [L-cysteine menA arabinose-5- dehydrogenase: dehydrogenase: phosphorylase: anaerobilin Fe Ada: ada ECTO60_RS11275 endopeptidase ammonia-ligase] cysteine desulfurase: MenF: menF synthase dihydroneopterin dihydroneopterin octanoyl-L-lysine ribosylamino)pyrimidin-4(3H)-one phosphate MenF: menF prenyl phosphate gorA an [L-cysteine a carboxy-adenylated cyclase alpha: accA pyruvate oxaloacetate nucleoside phosphorylase: GMP 5'-phosphate CTP protein: nrdG arnT cystathionine + partially peptide ABC DMAPP lipoate-- ribotide phosphate desulfurase]-S- phosphate UDP-3-O-[(3R)-3- gpsA gpsA deaminase: cobU MepM: mepM adenylyltransferase: phosphate H II: fabF MenF: menF 3'-triphosphate 3'-triphosphate lipoyl isochorismate desulfurase]-S- [small subunit of phosphorylase: ppnP glycosidase: peroxyureidoacrylate/ methylated-DNA-- beta-lyase ADP acetate deacetylated poly- met transporter met ECTO60_RS06575 protein bifunctional thiamine- adenosylcobinamide- sulfanyl-L-cysteine MoaA: moaA acetyl-CoA isomerase sn-glycerol sn-glycerol ECTO60_RS11650 ppnP adenosine acetyl-CoA C- a mature a nascent synthetase isochorismate hydroxymyristoyl]-N- nucleoside adenosyl- glnE a 3-oxoglutaryl- dihydroneopterin dihydroneopterin synthase: diaminohydroxyphosphoribosylaminopyrimidine phosphate sulfanyl-L-cysteine molybdopterin synthase] (8S)-3',8-cyclo-7,8- malate ppnP uridine ECTO60_RS08260 ureidoacrylate anaerobilin anaerobilin acetyltransferase: α di-trans,octa-cis [protein]-cysteine S- 3-hydroxy-5- MalY: malY β-1,6-N-acetyl- Asn of L- (2E,6E)- ligase GDP cysteine demethylmenaquinol-8 carboxylase, KdsD: kdsD acetyl-α-D-glucosamine 3-phosphate 3-phosphate purine-nucleoside 5'/3'- IMP triphosphatase an active cobinamide 4'- -L-Ara4N peptidoglycan peptidoglycan acetyl-CoA asn tRNA EntF: entF an S-sulfanyl-[L- isochorismate triphosphate triphosphate lipA 2-succinyl-5- dihydroguanosine D-lactate formate C- dehydrogenase: mdh phosphorylase: UMP 5'-deoxyadenosine a flavodoxin methyltransferase: oxohexanoate peptidoglycan peptidoglycan methionine [acp] methyl ester LplA: lplA deaminase/5-amino-6-(5-phosphoribosylamino) kinase: thiL glutathione a ThiS sulfur- SAH carboxyltransferase thymidine pyrimidine/purine phosphorylase: adenosine nucleotidase uracil FMN amidohydrolase RutB: rutB reductase: reductase: ECTO60_RS07970 met ribonucleoside a purine -α-Kdo-(2-> -undecaprenyl with (L-alanyl- (meso-DAP D-glucosamine farnesyl cysteine desulfurase] 2-succinyl-5- a [lipoyl-carrier enolpyruvyl- ribazoletransferase: desulfurase arabinose-5- UDP-3-O-acyl-N- glycerol-3- glycerol-3- dehydrogenase: ldhA NudI: nudI semiquinone phosphate tetrapeptide, tetrapeptide, diphosphatase: diphosphatase: a [lipoyl-carrier uracil reductase RibD: ribD carrier protein molybdopterin 5'-triphosphate subunit beta: accD acetyltransferase: pflB malate phosphorylase: nucleoside deaminase: SurE: surE IMP ECTO60_RS24280 5'/3'- chuY chuY [+ 3 isozymes] triphosphate 4)-α-KDO-(2- phosphate ECTO60_RS12560 γ containing) with a [glutamine 3-ketoacyl-ACP diphosphate enolpyruvyl- 2-succinyl-5- 6 thiamine cobS CsdA: csdA acetylglucosamine phosphate 1-O- phosphate 1-O- 2'-deoxyinosine deoD ribonucleoside -D-glutamyl- a seryl-[EntF formate RS15740 formate nudB nudB protein]-N -[(R) 6 6-hydroxy-3- prenylated FMNH synthase phosphate pyrimidine/purine glycan chain 1 glycan chain 2 scaffold protein]-N -[(R 5-amino-6-(5-phospho- Coα-[α-(5-methoxy-6- 2 cyclic pyranopterin 5'-methylthioadenosine/ [+ 2 isozymes] dehydrogenase: deoA phosphorylase: ECTO60_RS11650 dehydrogenase: CDP nucleotidase reductase >6)-lipid IV GlcNAc terminus synthetase]-O pyruvate reductase: synthase: ispA 6-hydroxy-3- enolpyruvyl- 7,8- 7,8- diphosphate IscS subfamily ThiS isomerase deacetylase: lpxC acyltransferase acyltransferase nucleoside [+ 4 isozymes] uracil carbamate (Z)-3-aminoacrylate 5'-diphosphate A meso-2,6- L-homocysteine L-seryl-carrier protein for -dihydrolipoyl]- cyclohexene-1- sulfurtransferase: monophosphate S-adenosylhomocysteine malonyl-CoA (R)-lactate ECTO60_RS12135 ppnP acetyl-CoA 4 -(5'-adenylyl) ECTO60_RS22120 6-hydroxy-3- )-lipoyl]-L-lysine D-ribosylamino)uracil methylbenzimidazolyl)]- UDP-3-O-(3- guaB SurE: surE β-anaerubin δ-anaerubin a [protein]-S- diaminopimeloyl- protein] geranyl cyclohexene- dihydroneopterin dihydroneopterin L-lysine carboxylic-acid cysteine desulfurase: adenylyltransferase: GutQ: gutQ PlsB: plsB PlsB: plsB phosphorylase: thymine a guanine in DNA a (3R)-3- iron-sulfur β ECTO60_RS10960 synthase nucleosidase: mtnN pyrimidine/purine purine-nucleoside methyl-L-cysteine -L-tyrosine 1-carboxylic- cyclohexene-1- 3'-phosphate 3'-phosphate bifunctional Co -adenosylcobamide ECTO60_RS06575 thiF malonyl CoA-ACP hydroxymyristoyl) (S)-malate ppnP inosine guanosine [+ 4 isozymes] D-alanine) diphosphate cluster synthase: menD MoaC: moaC aldehydo-D-arabinose α glycerol-3- glycerol-3- formate acetyl-CoA tyr RS10215 tyr hydroxyglutaryl- acid synthase: carboxylic-acid diaminohydroxyphosphoribosylaminopyrimidine 5'-phosphate a [ThiI sulfur- a carboxy- S-ribosyl-L- - -D-glucosamine nucleoside phosphorylase: XMP tetrapeptide (2E,6E)- assembly: iscU 2-succinyl-6- a thiocarboxylated transacylase: 5-phosphate UDP-3-O-(3- phosphate 1-O- phosphate 1-O- uridine CMP uridine [acp] methyl ester menD synthase: menD deaminase/5-amino-6-(5-phosphoribosylamino) adenosylcobalamin/ carrier protein]-S- adenylated-[ThiS cyclic pyranopterin homocysteine class I fumarate phosphorylase: deoD pyrimidine/purine pyrimidine/purine purine ribonucleosides degradation an S-sulfanyl-[cysteine hydroxy-2, 4- [small subunit of ECTO60_RS14615 acyltransferase acyltransferase phosphorylase: 5,6-dihydrouracil 3-hydroxyglutaryl- farnesyl uracil reductase RibD: ribD alpha-ribazole sulfanyl-L-cysteine sulfur-carrier protein] phosphate hydroxymyristoyl) formate phosphate acetaldehyde citrate (Si)- hydratase: ppnP nucleoside nucleoside 5'/3'- CO 3-oxopropanoate 5'/3'- desulfurase]-[disordered- 2-succinyl-6- 2-succinyl-6- AIR D-glyceraldehyde tyr molybdopterin synthase] S-ribosylhomocysteine PlsY: plsY PlsY: plsY ECTO60_RS24280 2 a mature peptidoglycan a peptidoglycan dimer a carboxy- a [ThiI sulfur- L-alanyl-γ-D- a mature a [glutamine iron(III)-[N-(2,3- [acp] methyl diphosphate cyclohexadiene- phosphatase: citrate lyase activation glucosamine N- synthase: gltA ECTO60_RS22635 nucleotidase S-(hydroxymethyl) D-erythro-7,8- D-erythro-7,8- 5-amino-6-(5-phospho- 3-phosphate a malonyl-[acp] a 1-acyl-sn a 1-acyl-sn hydrogenlyase: hycC acetyltransferase: pta dehydrogenase NADH repair purine-nucleoside phosphorylase: phosphorylase: nucleotidase 2-oxoadipate an L-cysteinyl- biotin RS24360 biotin form scaffold hydroxy-2, 4- hydroxy-2, 4- chorismate chorismate lyase: luxS malonic semialdehyde (meso-diaminopimelate with pentapeptide adenylated- cys carrier protein]- cys glutamyl-meso-2,6- peptidoglycan synthetase]-O 2,3- ser dihydroxybenzoyl)-L- ester synthase: ispA dihydroneopterin dihydroneopterin 1-carboxylate ECTO60_RS17565 adenylate:persulfide acyltransferase: hycD hycF hycG (acetylating): SurE: surE Aldehyde Degradation (n) glutathione GMP [tRNA Cys ] D-ribitylamino)uracil molybdopterin D-arabinofuranose -glycerol 3- -glycerol 3- phosphate [+ 4 isozymes] phosphorylase: ppnP ppnP SurE: surE adenosine 4 dehydratase: fabZ protein] complex cyclohexadiene- cyclohexadiene- synthase: menH Coα-[α-(5-methoxy-6- phosphomethylpyrimidine 1-deoxy-D-xylulose-5- 2-iminoacetate lpxD reductase: S-methyl-5'- containing) stems (meso- [ThiS sulfur- L-cysteine diaminopimeloyl- UDP-N-acetyl- (meso-DAP -(5'-adenylyl) dihydroxybenzoate formate serine trimer] complex (2E,6E)-farnesyl bifunctional aminodeoxychorismate bifunctional aminodeoxychorismate transferase: thiF synthase: 3'-dephospho-CoA ketoacyl-ACP 5-phosphate acetyltransferase: ECTO60_RS18860 deoD [+ 4 isozymes] [+ 4 isozymes] [cysteine desulfurase]-S- 1-carboxylate 1-carboxylate 5-amino-6-(5- methyl-benzimidazolyl)]- synthase ThiC: thiC phosphate synthase: synthase phosphate phosphate citrate NADH purine-nucleoside purine-nucleoside ECTO60_RS15000 diaminopimelate carrier protein] D-alanine α-D-muramate containing) -L-tyrosine hydrogenlyase 2-succinyl-5-enolpyruvoyl- L-homocysteine UDP-2-N,3-O-bis[(3R)- ECTO60_RS07625 fumarate 3-ureidopropanoate thioadenosine degradation I methylglyoxal degradation I 2-oxoglutarate a (2E)-enoylglutaryl- diphosphate sulfanylcysteine:[acceptor synthase: menH dihydroneopterin synthase dihydroneopterin synthase phospho-D- Coβ-adenosylcobamide ECTO60_RS18570 ThiH: thiH moaE moaD synthase III: 3-deoxy-8- acyl-CoA:1-acyl- acyl-[acp]:1-acyl- CO H phosphorylase: phosphorylase: adenosine cytidine transcriptional synthase: menH 6-hydroxy-3-cyclohexene- 3-hydroxytetradecanoyl]- 2 2 2-deoxy-α-D- methylglyoxal L-lactaldehyde L-lactaldehyde containing) IscS subfamily NADPH- aminoacyl-tRNA predicted [acp] methyl ester protein]-cysteine aldolase/7,8- component 2: pabA aldolase/7,8- component 2: pabA HMP-P triphosphoribosyl- ECTO60_RS13510 bifunctional xanthosine S-methyl-5'- membrane-bound dehydrogenase E1 enterobactin octaprenyl- 2-succinyl-5-enolpyruvoyl- ribitylamino)uracil 1-deoxy-D-xylulose a thiocarboxy- phosphooctulonate α sn-glycerol-3- sn-glycerol-3- acetaldehyde succinate deoD deoD deaminase: 3-hydroxypropanoate degradation (aerobic) degradation activator dependent nucleotide 5'- chorismate 2-succinyl-5- 1-carboxylate 2-iminoacetate dephospho-CoA -D-glucosamine 2-deoxy-α- ribose 1-phosphate degradation III lytic murein IscS subfamily cysteine desulfurase: UDP-N- component: sucA membrane-bound bifunctional [glutamate- non-ribosomal hydrolase: ABC enoyl-ACP diphosphate sulfurtransferase: dihydroneopterin aminodeoxychorismate dihydroneopterin aminodeoxychorismate [ThiS-Protein] ketoacyl-ACP synthase: kdsA phosphate 2-O- phosphate 2-O- aconitate hydratase uracil ECTO60_RS11650 thioadenosine5'-methylthioadenosine/ methylglyoxal monophosphate thiamine thiamine enolpyruvoyl-6- 6-hydroxy-3-cyclohexene- D-ribulose 5-phosphate phosphatase: ybjI 2-succinyl-6- bifunctional 5-phosphate molybdopterin synthase CitG: citG UDP-2,3- acetyl phosphate dehydrogenase/ D-ribose 1- phosphopentomutase: (anaerobic) transglycosylase N-acetylmuramoyl- cysteine desulfurase: ECTO60_RS06575 acetylmuramate:L- lytic murein -ammonia ligase]- peptide FlhA: flhA ferric chelate ECTO60_RS13635 transporter ECTO60_RS06575 epimerase: folB synthase epimerase: folB synthase synthase III: acyltransferase: acyltransferase: ethanolamine 2/2-methylisocitrate thymine hypoxanthine guanine 2-oxoglutarate reductase synthase: a [cysteine desulfurase]- hydroxy-3-cyclohexene- 1-carboxylate 5-amino-6-(5- hydroxy-2, 4- diacylglucosamine fumarate reductase S-adenosylhomocysteine lactoylglutathione methylglyoxal (S)-lactaldehyde S-(hydroxymethyl) reductase: nucleosidase: ppnN of thiamine hydroxymethylpyrimidine 2'-(5''-triphospho-α-D- KDO-8P plsC dehydratase: acnB phosphate deoB (S)-lactaldehyde EmtA: emtA L-alanine amidase: ECTO60_RS06575 cysteine alanyl-gamma-D- transglycosylase adenylyl-L-tyrosine synthetase aminoacyl-tRNA FabI: fabI ECTO60_RS02685 2-succinyl-6- 6-(hydroxymethyl) component 1: pabB 6-(hydroxymethyl) component 1: pabB 3,4-dihydroxy- cyclohexadiene- thiazole synthase: molybdopterin ECTO60_RS14620 diphosphatase: lpxH plsC utilization ethanol iron-sulfur: frdA (R)-NADHX degradation pyrimidine/purine adenosine inosine guanosine nucleosidase: mtnN lyase: gloA methylglyoxal dehydrogenase nfeF S-sulfanyl-[disordered- 1-carboxylate phospho-D- kinase/ L-cystathionine ribosyl)-3'-dephospho-CoA a 1,2-diacyl- a 1,2-diacyl- pyruvate fermentation propionate phosphopentomutase: phosphopentomutase: β-alanine (R)-S- lactaldehyde [+ 7 isozymes] ECTO60_RS16385 cysteine desulfurase glutamyl- meso- EmtA: emtA phosphorylase/ EntF: entF glutathione hydrolase: all-trans- hydroxy-2, 4- -7,8-dihydropterin 4-amino-4- -7,8-dihydropterin 4-amino-4- 2-butanone- 1-carboxylate ECTO60_RS23445 adenylyltransferase: dehydrogenase aconitate hydratase ECTO60_RS22420 nucleoside MTR reductase E1 component: a glutaryl-[acp] form scaffold 2-succinyl-6- ribitylamino)uracil phosphomethylpyrimidine kinase: tdcD bifunctional ADP- deoB thymine reductase: fucO desulfurase CsdA: csdA diaminopimelate [+ 5 isozymes] [glutamate-- dehydrogenase: D-ribose 5- ECTO60_RS19740 leu RS10745 leu octaprenyl ECTO60_RS20735 citrate lyase holo- an acetoacetyl-[acp] 3-deoxy- lipid X sn-glycerol sn-glycerol to ethanol II EutG: eutG AcnA: acnA ECTO60_RS01750 xanthine guanine phosphorylase: xanthosine pyrimidine deoxyribonucleotides lactoylglutathione YeaE: yeaE [+ 3 isozymes] ECTO60_RS23055 enterobactin methyl ester 4-hydroxybenzoate protein] complex hydroxy-2, 4- cyclohexadiene- 2-amino-4-hydroxy-6- deoxychorismate 2-amino-4-hydroxy-6- deoxychorismate 4-phosphate phosphatase synthase: menH kinase: thiD cystathionine [+ 3 isozymes] frdC frdD dependent NAD(P)H- (S)-lactate (S)-propane- ligase: mpl ammonia-ligase] ECTO60_RS18835 N-(2,3- phosphate diphosphate 2-[(2R,5Z)-2-carboxy- adenosylcobalamin [acyl-carrier protein] manno- 3-phosphate 3-phosphate phosphopentomutase: 2-deoxy-D-ribose dephosphorylation S-methyl-5- hydroxyacylglutathione a mature peptidoglycan a mature peptidoglycan CsdA: csdA synthase guanine cysteine cyclohexadiene- 1-carboxylate hydroxymethyldihydropteridine hydroxymethyldihydropteridine synthase: ribB (1R,6R)-6-hydroxy-2- molybdopterin alcohol dehydrogenase: deaminase: ppnP pyrimidine/purine pyrimidine/purine pyrimidine/purine hydroxyacetone Fe 2+ beta-ketoacyl- aminodeoxychorismate aminodeoxychorismate YigB: yigB gamma- 3-ketoacyl-ACP lipid-A- phosphatidate phosphatidate pyruvate cis-aconitate hydrate dehydratase/ ECTO60_RS01750 5-phosphate nucleoside triphosphate thioribose kinase: 1,2-diol γ strand (non- γ adenylyltransferase: S-formylglutathione dihydroxybenzoyl) desulfurase synthase: menH diphosphokinase: folK diphosphokinase: folK succinylcyclohexa-2,4- 4-methylthiazol-5(2H)- salvage from cobalamin adenine dinucleotide synthase: citX octulosonate-8- acetate dehydrogenase succinate 5,6-dihydrothymine xdhC xdhB xdhA guaD hydrolase GloC: gloC quinone-dependent with (L-alanyl- -D- a peptidoglycan dimer L-alanyl- -D- a [ThiI sulfur- a mature GlcNAc-1,6- subunit 1-carboxylate HMP-PP NAD(P)H-hydrate [+ 2 isozymes] nucleoside nucleoside nucleoside ACP synthase 4-hydroxybenzoate lyase: pabC lyase: pabC 1-deoxy-L-glycero- synthase: metB reductase: phosphatase disaccharide cytidylyltransferase: cytidylyltransferase: ubiquinone- 2-deoxy-D-ribose pyrophosphohydrolase: ECTO60_RS21390 glutamyl-meso-2,6- reducing terminus) with pentapeptide stem glutamyl-meso-2,6- carrier protein]- UDP-N-acetylmuramoyl- peptidoglycan anhMurNAc- glnE EntD: entD -L-serine trimer a tRNA Cys CsdA: csdA (1R,6R)-6-hydroxy-2- (7,8-dihydropterin- (7,8-dihydropterin- ARP diene-1-carboxylate ylidene]ethyl phosphate AdhP: adhP hydroxyacylglutathione bifunctional L- L-lactate ala CO glutaryl-CoA NADH (n) cys ala RS06080 ala synthase: menH tetrulose 4-phosphate molybdopterin a holo [citrate lyase synthase: lpxB dependent pyruvate bifunctional epimerase: pyrimidine/purine phosphorylase: phosphorylase: phosphorylase: a thiocarboxy- 2 II: fabF octaprenyltransferase: succinylcyclohexa-2,4- 6-yl)methyl 6-yl)methyl cob(I)alamin ECTO60_RS22120 KdsC: kdsC cdsA cdsA 5-phosphate deoxyribose- mazG 1,2-propanediol diaminopimeloyl-D- (meso-diaminopimelate diaminopimeloyl- ala S-sulfanyl- L-alanyl-γ-D- (meso-DAP L-Ala-γ-D-Glu- IscS subfamily (1R,6R)-6-hydroxy-2- 4-aminobenzoate 4-aminobenzoate o-succinylbenzoate molybdotransferase cys acyl-carrier protein] aconitate hydratase ppnP ppnP ppnP hydrolase: gloB dehydrogenase: lldD AMP lipid A disaccharide dehydrogenase: poxB ECTO60_RS22350 phosphate nucleoside 5-MTR-1-P [ThiS-Protein] beta-ketoacyl- ECTO60_RS23155 succinylcyclohexa-2,4- diene-1-carboxylate diphosphate diphosphate superpathway of pyridoxal 5'-phosphate biosynthesis and salvage thiamine a (3R)-3- a CDP- a CDP- ethanol (S)-NADHX xanthine nucleoside triphosphate dehydrogenase/ alanine) tetrapeptide containing) D-alanyl-D-alanine L-cysteine glutamyl-meso-2,6- containing) DAP-D-Ala a [glutamine- cysteine desulfurase: synthase: menC MoeA: moeA α-Kdo acetaldehyde 2/2-methylisocitrate phosphorylase: purine-nucleoside purine-nucleoside purine-nucleoside ACP synthase 6,7-dimethyl-8- phosphate (E. coli) diacylglycerol diacylglycerol deoxyribose- 3-(carbamoylamino)- aldolase: deoC pyrophosphatase (R)-lactate glycerol pyruvate diaminopimeloyl- synthetase]- enterobactin ECTO60_RS06575 diene-1-carboxylate o-succinylbenzoate superpathway of heme b MoO -molybdopterin [citrate (pro-3S)- glutathionylspermidine hydroxybutanoyl-[acp] dehydratase: acnB ATP-dependent NADH- adenosine xanthine S-methyl-5'-thioadenosine ppnP phosphorylase: phosphorylase: phosphorylase: ADP phe RS17935 phe I: fabB 3-octaprenyl-4- an S-sulfanyl-[cysteine dihydropteroate dihydropteroate ribityllumazine D-erythrose synthase: thiE 2 tetraacyldisaccharide pyruvate fermentation to acetoin III phosphate 2-methylpropanoate YhdE: yhdE dehydrogenase: D-alanine L-tyrosine o-succinylbenzoate synthase: menC biosynthesis from glutamate 2-succinylbenzoate cob(II)alamin cofactor lyase] ligase: citC biosynthesis 3-hydroxyacyl- 3-deoxy-manno- CDP-diacylglycerol-- CDP-diacylglycerol-- ethanolamine utilization aconitate hydratase hydrate dehydratase: nucleotides dehydrogenase: degradation IV hydroxybenzoate synthase: folP synthase: folP synthase: ribE 4-phosphate aldolase: [+ 2 isozymes] deoD deoD deoD dCTP dCMP gldA a 3-oxopimeloyl- desulfurase]-S- synthase: menC superpathway of coenzyme A biosynthesis I (bacteria) octulosonate 4'-kinase: lpxK glycerol-3-phosphate 3- glycerol-3-phosphate 3- ethanol dehydrogenase ECTO60_RS22350 acetaldehyde D-glyceraldehyde 3-phosphate degradation III xdhC xdhB xdhA C1 Compound Utilization and Assimilation an acetyl-holo [citrate ACP AcnA: acnA deoC 4-hydroxy-3- sulfanyl-[disordered- 2-succinylbenzoate o-succinylbenzoate- erythrose-4- ethanolamine glutathione spermidine cytidylyltransferase: phosphatidyltransferase: phosphatidyltransferase: EutG: eutG pyruvate S-methyl-5'- (S)-propane- [acp] methyl ester glu thiamine phosphate lyase acyl-carrier protein] dehydratase lipid IV (E. coli) α-D-ribose- polyprenylbenzoate form scaffold 7,8- 7,8- utilization cob(I)yrinic A acetaldehyde urate thioadenosine a DNA containing iron(III)-[N-(2,3- 2445 (25S)-3- val RS06015 val 2-succinylbenzoate 6,7-dimethyl-8-(1-D-ribityl)lumazine 3-methyl-2- a 5,10- -CoA ligase: menE phosphate kdsB pgsA pgsA alcohol dehydrogenase D-threo-isocitrate NADH AMP 5'-methylthioadenosine/ dUTP diphosphatase: pyruvate 1,2-diol formaldehyde oxidation 3-phenyl-2- 4-amino-4- a 2,3,4-saturated a peptide with a guanine a [protein]- 3-ketoacyl-ACP FabZ: fabZ D-glyceraldehyde 1-phosphate 34 lipid IV (E. coli) a 3-oxo acid succinyl-CoA acetate an N-modified FAD β-aspartyl dipeptide decarboxylase: ubiD protein] complex o-succinylbenzoate- dihydropteroate dihydropteroate dehydrogenase: thiamine- acid a,c-diamide 1-(3-sn- 1-(3-sn- (R)-3-amino-2- dehydrogenase S-adenosylhomocysteine ECTO60_RS00365 formaldehyde oxidation a 5,10-gly a uridine tyr deoxy-α-L- A an apurinic/ an N-terminal dihydroxybenzoyl) L-threonine oxocholest- reductase: [cysteine desulfurase]-S- oxobutanoate methylenetetrahydrofolate 4-(2'-carboxyphenyl) pyridoxal 5'-phosphate salvage II (plants) bifunctional 3-deoxy-manno- 3-deoxy-D-manno- AdhP: adhP ubiquinone- acetaldehyde nucleotide 5'- VII (THF pathway) oxopropanoate fatty acyl CoA aminoacyl-[tRNA] in 23S rRNA coenzyme A o-succinylbenzoate- -CoA ligase: menE bifunctional bifunctional riboflavin ECTO60_RS04675 adenosyltransferase phosphatidyl) phosphatidyl) NADP-dependent 3-phosphate methylpropanoate (acetylating): phosphopentomutase: [+ 2 isozymes] II (glutathione-dependent) methylenetetrahydrofolate in tRNA arabinopyranosyl apyrimidinic site Xaa-L-proline -L-serine] complex bifunctional 4-en-26-oate 2-octaprenylphenol sulfanylcysteine:[acceptor -4-oxobutyryl-CoA phosphate a (2E)-but-2-enoyl-[acp] octulosonate octulosonic acid monophosphate nucleosidase: mtnN ECTO60_RS22120 Glu glutathionylspermidine dependent pyruvate deoB dUTP dUMP -CoA ligase: menE 4-(2'-carboxyphenyl) tetrahydrofolate tetrahydrofolate an L-glutamyl-[tRNA ] synthase: ribE 3-methyl-2-oxobutanoate 4-phospho- kinase: thiL EutT: eutT -sn-glycerol -sn-glycerol ethanol ubiquinone- isocitrate acetaldehyde ECTO60_RS18860 MTR ditrans,octacis 23S rRNA D-ala D-ala a (3R)-3- protein]-cysteine 1,4-dihydroxy-2- amidase/synthase: cytidylyltransferase: transferase: dehydrogenase: poxB nucleosidase: ppnN formaldehyde acyl CoA:acetate/ acetate CoA- FAD:protein beta-aspartyl- synthase/ synthase/ D-erythronate superpathway of adenosylcobalamin salvage from cobinamide I cob(I)yrinic acid pyridoxal 3-phosphate 3-phosphate dehydrogenase: dehydrogenase phosphopentomutase: formaldehyde aspartate/ -undecaprenyl (guanine(2069)-N(7) D-serine RS22095 D-serine hydroxypimeloyl- FAD-dependent 2- sulfurtransferase: 4-(2'-carboxyphenyl) -4-oxobutyryl-CoA a 5,10- hydroxymethyltransferase: naphthoyl-CoA lipoate biosynthesis enoyl-ACP kdsB ECTO60_RS00400 dependent pyruvate AMP tRNA uridine(34) 5- bifunctional DNA- leucyl aminoacyl-tRNA NADPH- FMN acyl-CoA dihydrofolate dihydrofolate riboflavin thiamine diphosphate ECTO60_RS03705 phosphatidylglycerophosphatase phosphatidylglycerophosphatase ubiquinone- ECTO60_RS14395 acetyl-CoA ECTO60_RS01750 3-ketoacid CoA transferase peptidase: [acp] methyl ester octaprenylphenol ECTO60_RS06575 -4-oxobutyryl-CoA 1,4-dihydroxy-2- glutamyl-tRNA panB 4-phosphoerythronate a,c-diamide and incorporation reductase α dehydrogenase: poxB (acetylating): carboxymethylaminomethyl tyrosine/aromatic phosphate aminopeptidase: hydrolase: dependent )-methyltransferase synthetase gly gly a [cysteine methenyltetrahydrofolate synthase: menB -Kdo-(2->6)- nucleosidase: amn 5-hydroxy-CTP 5-hydroxy-CMP transferase: formamidopyrimidine subunit transferase iaaA hydroxylase: ubiI synthase: folC synthase: folC reductase: adenosyltransferase: FabI: fabI CMP-Kdo A: pgpA A: pgpA acetaldehyde dependent pyruvate ECTO60_RS18860 D-ribose 5- a 5,10- aminotransferase: pepA ECTO60_RS13635 ferric chelate RlmK/23S rRNA FdrA: fdrA 3-hydroxypimeloyl- desulfurase]-(S- 1,4-dihydroxy- naphthoyl-CoA bifunctional bifunctional asp 1,4-dihydroxy-2- dehydrogenase cob(II)inamide III (Bacillus) lipid IV (E. coli) 2-oxoglutarate adenine synthesis enzyme ECTO60_RS22135 glycosylase/ alpha: atoD ApbE: apbE pyridoxine/ A [+ 2 isozymes] [+ 2 isozymes] dehydrogenase: poxB phosphate S-(hydroxymethyl) ECTO60_RS15340 (guanine(2445)-N(2) beta-aspartyl- [acp] methyl ester 3-(all-trans synthase: menB 7,8-dihydrofolate 7,8-dihydrofolate hemA riboflavin kinase/ PdxB: pdxB cobO pyridoxal glutathionylspermidine methylenetetrahydrofolate MnmG: mnmG lipid IV(A) 4- DNA-(apurinic Xaa-Pro aminoacyl-tRNA reductase: [+ 2 isozymes] sulfanyl) -[disordered- 2-naphthoyl- (2E,6E)-farnesyl diphosphate methylenetetrahydrofolate 2-dehydropantoate naphthoyl-CoA pyridoxal/ an L-1- an L-1- acetyl-CoA glutathione acetate CoA- peptidase: serine serine -octaprenyl) 2 monoglutamate cob(I)yrinic acid a,c-diamide cob(II)alamin- phosphatase: an octanoyl-[acp] a butanoyl-[acp] bifunctional aromatic amino acyl CoA:acetate/ nfeF )-methyltransferase RS03150 dehydratase: fabZ form scaffold CoA 1,4-dihydroxy-2- dehydrogenase/ monoglutamate (S)-4-amino-5- FAD synthetase: ribF aspartate 1- (3R)-3-hydroxy-2-oxo- phosphatidyl- phosphatidyl- tRNA uridine-5- amino-4-deoxy-L- or apyrimidinic aminopeptidase: hydrolase: thr thr benzene-1,2-diol 1,4-dihydroxy-2- adenosyltransferase: cobO [corrinoid ECTO60_RS16890 pyridoxamine lipoyl(octanoyl) S-(hydroxymethyl) 3-ketoacid CoA transferase YdiF: RlmL: rlmKL a [protein]-FMN- iadA octaprenyl- oxopentanoate decarboxylase: acetoin methylenetetrahydrofolate acid transaminase: arabinosyltransferase: site) lyase: mutM pepP ECTO60_RS19740 2 (25S)-3- a (2E)-enoylpimeloyl- protein] complex synthase: naphthoyl-CoA methenyltetrahydrofolate 2-dehydropantoate naphthoyl-CoA 4 phosphooxybutanoate kinase: pdxK superpathway of unsaturated sn-glycerol sn-glycerol Respiration carboxymethylaminomethyl(34) ECTO60_RS11275 an N - bifunctional 3- diphosphate FMN panD adenosyltranferase] [+ 2 isozymes] pyridoxine 4- transferase beta-ketoacyl- dehydrogenase/ glutathione ECTO60_RS23060 transferase: AMP L-threonine [acp] methyl ester menB 1,4-dihydroxy-2- cyclohydrolase FolD: folD glutamate-1- 2-reductase: panE 3-phosphoserine/ KDO transferase: fatty acids biosynthesis (E. coli) synthesis GTPase MnmE: mnmE arnT endonuclease III: N-(2,3- methylguanine 2445 oxocholest-4- hydrolase: menI a [glycine-cleavage ECTO60_RS23090 2+ demethylubiquinone 3- synthase: [corrinoid adenosyltranferase]-cob(II)inamide pyridoxal dehydrogenase: LipB: lipB ACP synthase ECTO60_RS00400 Chemoautotrophic methenyltetrahydrofolate dehydrogenase: Fe 10 semialdehyde- phosphohydroxythreonine Inorganic Nutrient Metabolism dihydroxybenzoyl) in 23S rRNA en-26-oyl-CoA a proteinogenic serine serine enoyl-ACP 1,4-dihydroxy-2- naphthoyl-CoA an N - bifunctional β-alanine kinase complex H protein] menaquinol-9 biosynthesis II: fabF Energy Metabolism 2-oxoglutarate decarboxylation to succinyl-CoA ECTO60_RS18835 3-(4- ECTO60_RS11595 a peptide with asp RS03020 O-methyltransferase/2- (2E,6E)-farnesyl ECTO60_RS02685 a 7,8-dihydrofolate a 7,8-dihydrofolate 2,1- (R)-pantoate 1,4-dihydroxy-2-naphthoate pdxI Alcohol Degradation cyclohydrolase FolD: folD a 2,3,4-saturated a proteinogenic an N-modified an uncharged -L-serine hydrolase: menI transaminase: serC 6 34 di-trans,octa-cis an N-terminal amino acid thr thr reductase octaprenyl-6-hydroxy naphthoyl-CoA formyltetrahydrofolate riboflavin kinase/ PdxY: pdxY N -octanoyl-L-lysine beta-ketoacyl- a (3R)-3-hydroxydecanoyl-[acp] a 5-carboxymethylaminomethyluridine hydroxyphenyl) phe lipid II acetyl-CoA tRNA a [cysteine desulfurase]- diphosphate aminomutase: cob(I)alamin- formate a 7,8-dihydrofolate A a 2,3,4-saturated fatty acid amino acid amino acid FabI: fabI all-trans-octaprenyl FAD synthetase: ribF 4-phosphooxy- stearate biosynthesis (Kdo) -lipid A hydrogen oxidation a [2-oxoglutarate (aminomethyl)phosphonate degradation a 5,10- -undecaprenyl succinate L-proline phenol methylase: [scaffold protein- 1,4-dihydroxy- 1,4-dihydroxy-2-naphthoate demethylmenaquinol-9 ACP synthase 2 glyphosate degradation III superpathway of sulfate assimilation methylphosphonate dimethyl sulfide selenate reduction hydrogenlyase in tRNA pyruvate a 3'-terminal a 5'-phospho- octaprenyl- diphosphate dihydrofolate hemL [corrinoid biosynthesis II (P. putida) I (aerobic) dehydrogenase E2 superpathway of glycol two-component alkanesulfonate monooxygenase methenyltetrahydrofolate phosphate 3-oxoacyl-CoA ECTO60_RS07935 2-naphthoyl- dihydrofolate phosphoribosylglycinamide pantoate-- L-threonine I: fabB α-Kdo-(2->4)-α-Kdo- bifunctional 3- II (bacteria and plants) 2-oxoglutarate unsaturated sugar [DNA] a pimeloyl-[acp] (2Fe-2S)] complex reductase: folA adenosyltranferase] bifunctional 6 ethanol degradation II ethanol degradation I and cysteine biosynthesis degradation I degradation transcriptional serine diphosphate formyltransferase: purN FAD beta-alanine [corrinoid adenosyltranferase]-cob(I)inamide PLP pyridoxine hydroxydecanoyl- α-Kdo-(2->4)-α- protein] N -lipoyl-L-lysine metabolism and degradation glycerol degradation V bifunctional RS20985 serine methyl ester 2-methoxy- CoA reductase: folA 5-aminolevulinate 4-hydroxythreonine- demethylmenaquinone (2->6)-lipid IV (E. coli) dehydrogenase (aminomethyl)phosphonate activator cob(I)yrinic acid a [lipoyl-carrier protein] A H glyphosate II (oxidation) selenate thr thr 6-(all-trans- synthase: 1,4-dihydroxy- ligase: panC ACP dehydratase/ Kdo-(2->6)-lipid 2 an alkylsulfonate FMNH methylenetetrahydrofolate hydrolase: a tetrahydrofolate 4-phosphate 6 methyltransferase/2- a 3-oxohexanoyl-[acp] lauroyl a palmitoyl-[acp] E1 component: aminoalkylphosphonate sulfate methylphosphonate 2 FlhA: flhA a,c-diamide N -octanoyl-L-lysine phosphonate 34 α-Kdo-(2->4)- 2069 a [protein]-L- pimeloyl-ACP octaprenyl)phenol ECTO60_RS02685 2-naphthoate lipoate D-glyceraldehyde cob(I)yrinic acid a,c-diamide trans-2-decenoyl- IV (P. putida) Ni/Fe-hydrogenase Hydrogen ethylene glycol ethanol glycerol ethanol dimethyl sulfide sulfate dehydrogenase/ a 5,10- a 2-thiouridine quinoxaline-2- a ring-opened 7- N-acetyl-muramoyl-(L- methyl β-D-glucoside a guanine menI porphobilinogen pyruvate dehydrogenase methoxy-6-polyprenyl- acyltransferase: A TCA cycle sucA N-acetyltransferase: phnO phosphonate an unsulfurated (salicyl)adenylate acetate butanoyl-CoA CMP-Kdo MoO - 5 a tetrahydrofolate adenosyltransferase: TCA cycle I (prokaryotic) γ cys α-Kdo-(2->6)- 2 glutamate-O methyl ester 2-octaprenyl-6- a [co-chaperone]- polyprenyltransferase: salvage II 3-phosphate adenosyltransferase: cobO lipoyl 3-ketoacyl-ACP ACP isomerase: fabA LpxL/LpxP b-type cytochrome Production ethanolamine bifunctional L- ethanolamine C-P lyase sulfate adenylyltransferase: methenyltetrahydrofolate methylenetetrahydrofolate in tRNA aryl-carrier protein carboxyl adenylate cys methylguanine in DNA alanyl- -D-glutamyl-L- 6-phosphate in 23S rRNA ATP xanthosine all-trans-octaprenyl 1,4-dihydroxy- NAD de novo biosynthesis synthase: hemB PdxA: pdxA cobO 1,4-benzoquinol lpxL 2-oxoglutarate (acetamidomethyl)phosphonate C-P lyase S-formylglutathione [sulfur carrier] molybdopterin serine serine esterase [scaffold protein- thiamine salvage II (R)-pantothenate pyridoxamine subunit: hyaC lactaldehyde utilization ethanol system protein 3-phospho-D-glycerate ECTO60_RS05630 cyclohydrolase FolD: folD lysyl-D-alanyl-D-alanine) lipid IV (E. coli) bifunctional -methyl-ester methoxyphenyl diphosphate menA a [lipoyl-carrier adenosylcob(III) pyridoxine/ synthase: lipA reductase: α α 3-hydroxyacyl- family Kdo(2)- 2-oxoglutarate 1,2-propanediol utilization ethanol adenylyltransferase: system protein A RS20990 2-naphthoate I (from aspartate) aminopropanol 1-deoxy-D-xylulose-5- 4-hydroxythreonine- adenosylcobinamide pyridoxal methylase UbiE: ubiE -Kdo-(2->4)- - a 3-oxooctadecanoyl- A(H2) dehydrogenase hydrogen reductase: fucO PhnG: phnG cofactor thr thr BioH: bioH (2Fe-2S)] complex 6 5'-phosphate acetyl-CoA dehydrogenase dehydrogenase dehydrogenase/ dehydrogenase ECTO60_RS05630 cysN 10 S-formylglutathione 23S rRNA hydroxylase: ubiH porphobilinogen protein]-N -[(R type I alamin-[corrinoid pyridoxal/ a [lipoyl-carrier menaquinol-9 ECTO60_RS22120 Kdo-(2->6)-(lauroyl) ACP dehydratase [acp] lipid IV(A) lauroyl/ E1 component: phosphonate C- D-3- PhnG: phnG dimethyl sulfoxide adenosine 5'- an N - tRNA uridine(34) 5- bifunctional DNA- acetate CoA- 6-phospho-beta- SSQ1 phosphate 4-phosphate phosphatase: 6 production V 2-methoxy-6-all 4-amino-2-methyl-5- )-lipoyl]-L-lysine phosphate synthase: pyridoxine oxidase: pdxH pyridoxamine protein]-N -[(R)- palmitoleoyl E1 component: EutG: eutG glycerol EutG: eutG α-D-ribose-1-[[+N 3- isozymes] cysN hydrolase: fghA acyl carrier IscS subfamily serine-type yersiniabactin 3-deoxy-D- (guanine(2069)-N(7) chemotaxis 1,4-dihydroxy- demethylmenaquinol-8 NAD biosynthesis from 2-amino- pantothenate dehydrogenase: bifunctional adenosyltranferase] a (3R)-3- -lipid IV (E. coli) FabZ: fabZ ECTO60_RS23055 glycolaldehyde P lyase system phosphoglycerate α [+ 2 isozymes] phosphoselenate formyltetrahydrofolate carboxymethylaminomethyl formamidopyrimidine transferase YdiF: glucosidase: a pimeloyl-[acp] trans-octaprenyl- chaperone: asp pyrimidinemethanol biosynthesis II ECTO60_RS18570 ECTO60_RS16890 A 3-ketoacyl-ACP -D-ribose-1- )-methyltransferase molybdenum cofactor ribonucleoside hydroxymethylbilane kinase: coaA pyridoxamine kinase: pdxK dihydrolipoyl]-L-lysine lauroyl-Kdo(2) acyltransferase: oxaloacetate sucA alcohol dehydrogenase: alcohol protein PhnG: phnG (phosphonomethyl) NAD(P)H-flavin S-formylglutathione protein: acpP cysteine desulfurase: D-Ala-D-Ala non-ribosomal manno-oct-2- response regulator dnaK 2-naphthoate 3-carboxymuconate semialdehyde ECTO60_RS21780 pyridoxamine adenosylcobinamide cob(I)yrinic acid hydroxyhexanoyl-[acp] reductase: a [2-oxoglutarate formate APS dehydrogenase: methylphosphonate- cyanate degradation formyltetrahydrofolate synthesis enzyme glycosylase/ ECTO60_RS11275 ECTO60_RS04800 guanylyltransferase hydrolase 1,4-benzoquinol L-aspartate bifunctional synthase: hemC lpxL a [2-oxoglutarate[+ 3 isozymes] dehydrogenase gldA dehydrogenase glycine] 5-triphosphate hydrolase: fghA acyl carrier protein: ECTO60_RS06575 carboxypeptidase: peptide ulosonate III RlmK/23S rRNA protein-glutamate thr RS24385 thr a [chaperone-ATP]- polyprenyltransferase: 2-amino-3- thr (R)-lipoate (R)-4'- 1-deoxy-D- 3-amino-1- kinase/adenosylcobinamide- a,c-diamide 5'-phosphate pyridoxal -lipid IV(A) a (2E)-dec-2-enoyl-[acp] dehydrogenase [+ 2 isozymes] ECTO60_RS04735 5-triphosphate FMNH2-dependent reductase: deformylase: purU MnmG: mnmG DNA-(apurinic acetate CoA- 6-phospho-beta- 8-amino-7- bifunctional hydroxymethylpyrimidine pyridoxine/ 3-hydroxyacyl- ECTO60_RS22120 α-Kdo-(2->4) dehydrogenase E2 protein] dihydroxyacetone alpha-D-ribose 1- synthetase (guanine(2445)-N(2) MobA: mobA RihC: rihC methylesterase: [co-chaperone]- menA oxidase: nadB L-threonine 3- phosphopantothenate hydroxyacetone pyridoxine/ phosphate adenosyltransferase: oxidase: pdxH kinase myristoyltransferase: E2 protein] N 6 -S- AdhP: adhP AdhP: adhP α-D-ribose 1- alkanesulfonate ECTO60_RS24195 ECTO60_RS03760 cysteine or apyrimidinic dacC transferase oxononanoate carboxymuconate- xylulose 5- pyridoxal/ pyridoxamine a (3R)-3- α citrate (Si)-synthase: gltA 6 adenylyl-sulfate alpha-D-ribose 1- formate tRNA uridine-5- transferase glucosidase: )-methyltransferase demethylmenaquinone 2-iminosuccinate kinase/ preuroporphyrinogen dehydrogenase: lipoate-- menaquinol-6 biosynthesis ACP msbB bifunctional 3- - -Kdo-(2->6) N -dihydrolipoyl-L-lysine acetaldehyde acetaldehyde (acetamidomethylphosphonate) methylphosphonate 3-phosphooxypyruvate dimethyl sulfone CO desulfurase [+ 3 isozymes] HMWP2: irp2 WaaZ: waaZ ECTO60_RS10325 [scaffold protein- 6-semialdehyde phosphate 1-phosphate pyridoxal/ guanylyltransferase: cobU cobO 5'-phosphate PdxY: pdxY hydroxyoctadecanoyl- succinyldihydrolipoyl-L-lysine a reduced methylphosphonate selenite monooxygenase: NADPH- 2 formate carboxymethylaminomethyl(34) site) lyase: mutM subunit ECTO60_RS11080 synthase: bioF methyltransferase/2- phosphomethylpyrimidine bifunctional pyridoxamine dehydratase α -(lauroyl)-lipid malate dehydrogenase glycolate dihydroxyacetone 5-triphosphate kinase: cysC carbonate RlmL: rlmKL adenylyl thioredoxin ECTO60_RS00480 protein pyridoxamine pyridoxine 5'-phosphate -D-Kdo-(2->4) hydroxydecanoyl- 5-triphosphate a quinoxaline-2- CsdA: csdA an N 7 - D-ribofuranose Ptd Gro RS08140 Ptd Gro 8-amino-7- methoxy-6-polyprenyl- (2Fe-2S)] complex NAD salvage quinolinate uroporphyrinogen- phosphopantothenoylcysteine kinase: pdxK [acp] (quinone): mqo hydrogenase acetaldehyde kinase: dhaL dhaM 3-phosphoserine 5-triphosphate ssuD dependent FMN dehydratase: synthesis GTPase MnmE: mnmE alpha: atoD molybdenum xanthine 2 2 demethylmenaquinol-8 kinase: thiD adenosylcobalamin folate transformations III (E. coli) FabZ: fabZ α IV (P. putida) acetaldehyde diphosphatase: phnM α 2069 pathway L-threonine ligase pyridoxine 5'- kinase: pdxK adenosyl-cobinamide phosphate - -D-Kdo-(2->6) ACP dehydratase/ 3-hydroxyacyl- A alpha-D-ribose 1- PAPS carboxyl-[aryl- N-acetyl-muramoyl-(L- CMP -Kdo-(2->4) methylguanine α oxononanoate 1,4-benzoquinol pathway IV (from synthase quinolinate III synthase: hemD decarboxylase/ demethylmenaquinol-6 malate dehydrogenase: mdh glycolate dehydrogenase: α-D-ribose-1-[N- aminotransferase: diphosphatase: phnM reductase: ssuE ECTO60_RS20090 AMP 2,6-diamino-4- β cofactor a [protein]- - LplA: lplA pyridoxal 5,6-dimethylbenzimidazole pyridoxine/ -lipid A (E. coli) trans-2-decenoyl- dehydrogenase methylphosphonate α-D-ribose-1- an apurinic site γ yersiniabactin -α-Kdo-(2-> -D-glucose MeOH SSQ1 nicotinamide riboside) NadA: nadA dehydrogenase: phosphopantothenate-- pyridoxal phosphate pyridoxal bifunctional ACP malate dehydrogenase: oxidase: adhE DHAP (phosphonomethyl) serC carrier protein] hydroxy-5-(N-methyl) alanyl- -D-glutamyl- D-ala AMP MeOH in 23S rRNA L-glutamate adenosylmethionine- methylase UbiE: ubiE bifunctional an oxidized HMP-P kinase pyridoxal/ a (2E)-hex-2-enoyl-[acp] lipopolysaccharide (acetylating): 5-triphosphate phosphoadenosine methylphosphonate a 5-aminomethyl-2- a sulfurated within DNA 4)-α-Kdo-(2- 6-phosphate chaperone 1-(β-D carboxylating uroporphyrinogen-III yiaY cysteine ligase CoaBC: coaBC synthase: bifunctional a tetrahydrofolate demethylmenaquinone ACP isomerase: fabA dehydratase ECTO60_RS12135 glcD glcF glycine] 5-phosphate methanesulfinate a 7,8-dihydrofolate ala formamidopyrimidine L-lysyl-D-alanine) acetyl-CoA butanoate -8-amino-7- 6-methoxy-3- demethylmenaquinone thioredoxin L-2-amino-3- (lipoyl)adenylate PdxY: kinase nicotinate-nucleotide-- pyridoxamine 2-oxoglutarate ECTO60_RS18860 34 [sulfur carrier] a purine RS04875 a purine ATPase: dnaK ribofuranosyl) quinolinate 5-(2-hydroxyethyl) pdxJ adenosylcobinamide pyridoxal heptosyltransferase FabZ: fabZ α-Kdo-(2->4) acetate diphosphatase: phnM phosphosulfate 5-phosphate selenodiglutathione thiouridine in tRNA >6)-lipid IV methyl-2-all- methyltransferase/2- bifunctional nicotinate- (R)-4'- pdxY PdxY: dimethylbenzimidazole methyltransferase/2- enoyl-ACP dehydrogenase a reduced α-D-ribose-1-(2-N- alpha-D-ribose 1- O-phospho-L-serine A oxononanoate oxobutanoate pyridoxine/ kinase/adenosylcobinamide- kinase: pdxK phosphatase: RfaC: rfaC a (3Z)-dec-3-enoyl-[acp] -α-Kdo-(2->6) glyoxylate reductase: alpha-D-ribose 1- trans-octaprenyl- methoxy-6-polyprenyl- nicotinamidemultifunctional -4-methylthiazole hydroxymethylpyrimidine nucleotide uroporphyrinogen lipoate-- phosphopantothenoyl- pdxY phosphoribosyltransferase: methoxy-6-polyprenyl- reductase a (2E)-octadec- (S)-malate citrate E1 component: hydrogenase 3 acetyl-CoA acetamidomethylphosphonate) methylphosphonate carbamate hydrogencarbonate transaminase: bioA a [chaperone- carboxylating pyridoxal/ phosphate pyridoxal ECTO60_RS16890 methionine -lipid A form acetate--CoA ECTO60_RS17730 methylphosphonate 1,4-benzoquinol an [2Fe-2S] 1,4-benzoquinol transcriptional hydroxyethylthiazole kinase/ diphosphorylase: decarboxylase: hemE protein L-cysteine cobT 1,4-benzoquinol FabI: fabI heptosyl-Kdo -lipid A 2-enoyl-[acp] sucA 5-phosphate 5-phosphate C-P- phosphoserine a ribonucleoside ADP]-[disordered- thioredoxin- nicotinate- pyridoxamine pyridoxine pyridoxamine guanylyltransferase: cobU kinase synthase: metH 2 beta-ketoacyl-ACP C (P. putida) ligase: acs 5-phosphate C-P- a 7,8-dihydro-8- arbutin-6- phosphoenol Mo 2+ RS16895 Mo 2+ 7,8-diaminopelargonate cluster protein regulator/nicotinamide- phosphomethylpyrimidine nadC ligase bifunctional methylase UbiE: ubiE bifunctional aconitate formate lyase PhnJ: phnJ [+ 2 isozymes] phosphatase: a [formate C acetyltransferase]-glycine a peptidoglycan a peptidoglycan F6P a (6S)-5- acetate pentanoyl-CoA NaMN a RNA-DNA hybrid 2-octaprenyl- form scaffold methylase UbiE: ubiE disulfide nucleotide kinase: thiM kinase: pdxK 5'-phosphate 5'-phosphate synthase II: fabF enoyl-ACP [+ 2 isozymes] glyoxylate malate alpha-D-ribose 1- an aldehyde FMN a reduced flavodoxin SAM glu oxoguanine in DNA 2',3'-cyclic phosphate coproporphyrinogen III PdxY: pdxY lyase PhnJ: phnJ GTP dGDP pyruvate nucleotide kinase: thiD LplA: lplA phosphopantothenoylcysteine α-ribazole 5'-phosphate menaquinol-6 a hexanoyl-[acp] ADP-heptose--LPS hydratase 2/2- hydrogenlyase: synthase methylphosphonate α ECTO60_RS20855 α methanesulfonate formyltetrahydrofolate phosphate bifunctional UDP- oxidized 3-methyl-6- protein] complex reductase: diphosphorylase: 4-methyl-5-(2- pyridoxal adenosylcobinamide-GDP beta-ketoacyl-ACP reductase carboligase: acetyl-CoA 5-phospho- -D-ribose sulfite 5-phospho- - glutathioselenol 2',3'-cyclic-nucleotide ATP- menaquinol-8 adenylyltransferase/ NaMN aminoacetone a [glycine- decarboxylase/ dihydrofolate heptosyltransferase methylisocitrate hycC hycD factor 420-2 methoxy-1,4- non- trxB nadC phosphooxyethyl) synthase I: fabB FabI: fabI gcl A: aceB glycerol and glycerophosphodiester degradation 5-phosphate C-P- 1,2-cyclic phosphate D-ribose 1,2- FMNH2-dependent N-acetylmuramoyl- 2'-phosphodiesterase: sugar hydrolase/ dependent ribosylnicotinamide HMP-PP coproporphyrinogen cleavage complex kinase pyridoxamine pyridoxamine reductase:serine folA beta-ketoacyl- RfaF: rfaF dehydratase: acnB hycF hycG ser bifunctional fructose-6- bifunctional DNA- acetate CoA- 6-phospho-beta- ribonuclease benzoquinol chaperonin thiazole nicotinate-nucleotide phosphopantothenate-- pyridoxamine α α malate lyase PhnJ: phnJ α NADPH-dependent cyclic phosphate alkanesulfonate pyruvate formate lyase bifunctional cpdB 5'-nucleotidase: lipid A RS15410 lipid A dethiobiotin III oxidase: hemF D-aminopropanol H protein] N 6 -[(R PdxY: 5'-phosphate 5'-phosphate adenosylcobinamide-GDP a 7,8-dihydrofolate a 5-methyltetrahydrofolate ACP synthase (heptosyl) - -Kdo-(2->4) -Kdo-(2->4) class I fumarate hydratase: 5-phospho- -D-ribosyl CO L-alanine amidase: chitinase/ phosphate formamidopyrimidine transferase YdiF: glucosidase: HI: rnhA kinase NadR: nadR cysteine ligase CoaBC: coaBC hydroxymethyltransferase: 2 aconitate hydratase tartronate assimilatory α 2 1-activating protein: pflA ECTO60_RS18270 coenzyme F390 hydroxylase: molecular NaMN adenylyltransferase: dehydrogenase: pdxY oxidase: pdxH oxidase: pdxH a (5Z)-3-oxododec-5-enoyl-[acp] a stearoyl-[acp] -α-Kdo-(2->6) -α-Kdo-(2->6) H synthase 5-phospho-α-D-ribose 1,2-cyclic phosphate serine O- 5-phospho- -D-ribosyl monooxygenase: cyanate ECTO60_RS16385 tetrahydrofolate pyruvate synthetase NMN )-lipoyl]-L-lysine ribazoletransferase: cobS ECTO60_RS06500 glycine cleavage system II: fabF Kdo -lipid A ECTO60_RS22635 2 a glycerophosphodiester lysozyme: aldolase: fsa glycosylase/ ECTO60_RS11275 fused tRNA ECTO60_RS04800 ribonuclease ubiF a reduced thiamine nadD protoporphyrinogen IX 2 AcnA: acnA semialdehyde G: glcB sulfite reductase 1,2-cyclic phosphate [formate-C- synthetase: BioD: bioD chaperone gldA 4'-phosphopantetheine aminomethyltransferase -lipid A form -lipid A form [+ 4 isozymes] 1,2-cyclic phosphate phosphodiesterase: acetyltransferase: ssuD nitrate [+ 3 isozymes] chiA synthase/ nucleotidyltransferase/ bifunctional kinase: pyk nicotinate-nucleotide phosphate beta-ketoacyl- lipopolysaccharide 3-oxo-cis-∆ 5 - glycerol glycerol degradation II flavoprotein: hydrogen selenide fructose-6- DNA-(apurinic acetate CoA- 6-phospho-beta- HII: rnhB ECTO60_RS13495 ATPase: hscA thioredoxin nicotinate adenine folate transformations I NAD salvage pathway II (PNC IV cycle) thymidylate D (P. putida) A (P. putida) 2-hydroxy-3- α phnP cysE phosphodiesterase: acetyltransferase]- dihydrofolate metallophosphatase/ fluoride RS17630 fluoride 3-demethylubiquinol-8 adeninyl adenosylcobamide multifunctional adenylyltransferase: (R)-1- GcvT: gcvT a (6S)-5-formyltetrahydrofolate ACP synthase glucosyltransferase: fumarate cis-aconitate 5-phospho- -D-ribosyl cysJ cysI sulfite reduction IV lysozyme: phosphate or apyrimidinic transferase 2',3'-cyclic glucosidase: ATP- an [Fe-S cluster synthase: thiE dinucleotide protoporphyrinogen PLP adenosylcobalamin 5'-phosphate synthase: thyA bifunctional dodecenoyl-[acp] oxopropionate glycerophosphodiester phnP activating enzyme: synthase: folC 5'-nucleotidase: transcriptional nadD aminopropan-2-ol pantetheine- [+ 2 isozymes] I: fabB ECTO60_RS00410 (S)-malate 1,2-cyclic phosphate α-D-ribose 1,5- (dissimilatory) ditrans,octacis- ECTO60_RS13180 site) lyase: mutM phosphodiesterase/ dependent biosynthesis biosynthesis from oxidase: hemG a [lipoyl-carrier NAD salvage a 5,10- methylenetetrahydrofolate5-formyltetrahydrofolate reductase: fabG reductase: phosphodiesterase: ugpQ glycerol glycerol α ECTO60_RS23645 a peptidoglycan aldolase: fsa subunit ECTO60_RS11080 3-demethylubiquinone- phosphate + O-acetyl-L-serine -D-ribose 1,5- ECTO60_RS23700 a nucleoside 5'- regulator/nicotinamide- ammonia- 6 5-methoxybenzimidazolyl NAD heme b biosynthesis II glucosyl-(heptosyl) succinate dehydrogenase: phosphodiesterase: phnP bisphosphate hydrogen sulfide urea cycle undecaprenyldiphospho- 2' nucleotidase/ DNA pyruvate dethiobiotin chaperone]-ATP adenosylcobinamide-GDP nicotinate adenine protein]-N -[(R pathway III (to methylenetetrahydrofolate adenosylcobalamin/alpha- dehydrogenase/ cyclo-ligase: stearate bifunctional aconitate ECTO60_RS02990 glycerophosphodiester kinase: bifunctional L- nitrate phosphate acquisition pentapeptide alpha: atoD β-D- coenzyme F -G 8 3-O- nucleotide thiamine phosphate dependent adenylyltransferase: (oxygen-independent) a (3R,5Z)-3-hydroxydodec- ECTO60_RS17110 bisphosphate phosphatase Cca: cca monophosphate 390 dGTP synthetase dinucleotide protoporphyrin IX )-lipoyl]-L-lysine nicotinamide riboside) adenosylcobamide biosynthesis methylenetetrahydrofolate a 3-oxooctanoyl-[acp] -Kdo -lipid A α-Kdo-(2->4) hydratase 2/2- 1,2-propanediol nitrate N-acetyl-(N- N-acetyl-D- a N-acetylmuramoyl- a (6S)-5- ribosylnicotinate 2+ 2+ ribazole phosphatase: methenyltetrahydrofolateECTO60_RS04745 2 2 2-hydroxy-3- phosphodiesterase: glpQ glpK α-D-ribose 1,5-bisphosphate ribose 1,5- a [formate C acetyltransferase]- D-glyceraldehyde 7,8-dihydro- an apurinic site a ribonucleoside β-D-glucose Ca RS02640 Ca methyltransferase: adenylyltransferase/ NAD(+) coaD from adenosylcobinamide-GDP methylenetetrahydrofolate reductase: metF 5-enoyl-[acp] -α-Kdo-(2->6) sdhA sdhC 5'-deoxyadenosine acetylglucosaminyl)muramate glucosamine pentapeptide- dihydroxyacetone formyltetrahydrofolate hydroquinone BioD: bioD adenine ammonia- ammonia- (R)-1-amino- NADP + ECTO60_RS17565 cyclohydrolase FolD: folD lipopolysaccharide long-chain- methylisocitrate dehydrogenase/ bisphosphokinase: cysteine arg reductase a phosphate a flavodoxin semiquinone met 3-phosphate 8-oxoguanine within DNA 6-phosphate ECTO60_RS07935 ribosylnicotinamide thiamine- synthetase: deferrochelatase/ reductase: metF uroporphyrinogen-III 3-ketoacyl-ACP ∆ 5 oxopropionate taurine glycin -2-yl radical 3'-phosphate + a 5,10-methylenetetrahydrofolate a 5,10-methenyltetrahydrofolate 3-hydroxy cis - -lipid A form succinate dehydrogenase/ glycerol diphosphoundecaprenol acetyl-CoA pentanoate nicotinate-nucleotide-- dependent dependent 2-propanol O 3'-dephospho-CoA NADP 5-methoxybenzimidazole core heptose(I) fatty-acid-- dehydratase: acnB reductase: glxR sn-glycerol ribose 1,5- phnN synthase B: cysM cytochrome monoesteracid phosphatase dethiobiotin kinase NadR: nadR phosphate nadE peroxidase a 5,10- adenosylcobalamin uroporphyrinogen reductase: dodecenoyl-[acp] B (P. putida) degradation IV ubiquinol-8 tetrahydromonapterin dimethylbenzimidazole NAD(+) NAD(+) -2-phosphate phosphatase: nicotinate-nucleotide-- bifunctional kinase RfaP: rfaP CoA ligase fumarate reductase aconitate hydratase dehydrogenase: c-type: kinase: thiL EfeB: efeB dephospho- a 5-methyltetrahydrofolate decarboxylase: hemE bifunctional ECTO60_RS22120 3-phosphate bisphosphokinase: phnN PRPP cysteine AphA: phosphoribosyltransferase: + methylenetetrahydrofolate dehydratase: fabZ iron-sulfur subunit: gldA hydrogen sulfide allantoin RS18110 allantoin biosynthesis nicotinamide- synthetase: synthetase: NAD phoA dimethylbenzimidazole methylenetetrahydrofolate ammonia- NAD(+) glucosyl-(heptosyl) - FadD: fadD AcnA: acnA (R)-glycerate synthase A: cysK thiosulfate argininosuccinate napA napB ECTO60_RS23010 biotin synthase: ferrochelatase: NAD salvage pathway I (PNC VI cycle) CoA kinase: coproporphyrinogen III methylenetetrahydrofolate 2 anaerobic glycerol- biosynthesis I taurine adenosine DNA with adenine:7,8- cobT nucleotide nadE nadE thiamine diphosphate NAD + phosphoribosyltransferase: serine dehydrogenase/ a (3R)-3- Kdo -lipid A-phosphate [+ 3 isozymes] ECTO60_RS22420 dihydroxyacetone PRPP adenine disproportionation nitrite a [ribosomal D-cellobiose phosphoenol methionine dependent diphosphatase: 2 taurine lyase: argH phosphate (S)-2- O-succinyl-L- ECTO60_RS16845 adenine ribotide ECTO60_RS18295 coaE dehydrogenase/ a (2E,5Z)-dodeca-3,5-dienoyl-[acp] 3-phosphate ammonium a sulfurated protein S12] acyl-carrier protein a 2,3,4-saturated a charged tRNA a peptidyl-[tRNA] glu 2',3'-cyclic dihydro-8- 1-butanesulfonate adenylyltransferase: cobT hydroxymethyltransferase: methenyltetrahydrofolate NAD(+) nudC oxygen-independent hydroxyoctanoyl-[acp] lipopolysaccharide succinate D-threo-isocitrate glycerate phosphoribosyltransferase: IV (rhodanese) 6'-phosphate dGTP IMP homoserine ATP dADP pyruvate phosphate + + synthase: metH methenyltetrahydrofolate stearoyl-CoA dioxygenase: [sulfur carrier] 89 aminobutanoate oxoguanine mismatch oxidized GTP ECTO60_RS23065 NAD NAD NAD(+) 5-methoxybenzimidazole ECTO60_RS06500 5-methylbenzimidazolyl acyl-CoA hydrolysis 2-kinase: dehydrogenase: adenine cys cys cytochrome L-aspartate fatty acid monophosphate chloride RS11815 chloride biotin protoheme coenzyme A cyclohydrolase FolD: folD synthetase: coproporphyrinogen cyclohydrolase FolD: folD 3-hydroxyacyl- core NADP-dependent ECTO60_RS18325 thiosulfate tauD carbamoyl- fused tRNA factor 420-2 GTP diphosphatase: ribotide phosphate adenosylcobamide biosynthesis enoyl-ACP ADP-forming garK glpC glpA phosphoribosyltransferase: L-arginino- c nitrite + nadE III oxidase: hemN ACP heptosyltransferase isocitrate dehydrogenase: 2-aminoacetaldehyde nucleotidyltransferase/ FMNH2-dependent adenosylcobinamide- NAD nudC methylenetetrahydrofolate reductase FabI: fabI ECTO60_RS18325 L-ornithine phosphate reductase 6-phospho-beta- cyclohydrolase 5-hydroxybenzimidazolyl adenosylcobinamide- nicotinate adenine from adenosylcobinamide-GDP 10 a 2,3,4-saturated succinate--CoA ligase 2-phospho- diphosphate succinate 30S ribosomal bifunctional 2- bifunctional glutamate-- 2',3'-cyclic A/G-specific cystathionine GDP S-adenosyl-L-methionine cycle I NAD(+) 5-formyltetrahydrofolate nicotinamide- NMN an N -formyltetrahydrofolate dehydratase RfaQ: rfaQ ECTO60_RS14395 DHAP DHAP synthase: glucosidase: alkanesulfonate 2-methyladeninyl I FolE: folE adenosylcobamide biosynthesis GDP dehydrogenase: folD dinucleotide protoporphyrinogen IX fatty acyl CoA subunit beta: sucC D-glycerate thiosulfate subunit acylglycerophosphoethanolamine glycosyl nucleotide 5'- cysteine ligase: adenine gamma- coenzyme F390 7,8-dihydroneopterin ribazoletransferase: diphosphatase: NMN cyclo-ligase: 5-methylbenzimidazole NaMN FabZ: fabZ glucosyl-(heptosyl) - multifunctional acyl- diphosphate 3-mercaptopyruvate protein S12 ECTO60_RS04800 dGTPase: phosphodiesterase/ monooxygenase: pyruvate ammonia- nucleotide 3 carB carA NrfD: nrfD synthetase: potassium- adenosylcobamide biosynthesis heme a biosynthesis from adenosylcobinamide-GDP ribazoletransferase: benzimidazolyl adenosylcobamide a (5Z)-dodec-5-enoyl-[acp] ADP-forming superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass inorganic sulfurtransferase methylthiotransferase acyltransferase/acyl-ACP transferase/ ECTO60_RS19890 monophosphate ECTO60_RS17910 2' nucleotidase/ glycosylase: synthase: metB kinase: pyk 3'-triphosphate cobS dependent nudC glycine cleavage system a 5,10- ECTO60_RS04745 a (6S)-5- Kdo -lipid A-phosphate biotin-carboxyl carrier protein assembly CoA thioesterase ssuD + + α α amidase: pncC 2 diphosphatase: 3-mercaptopyruvate carbamoyl 6-phospho-beta- nucleosidase: ppnN ECTO60_RS13495 K transporting K from adenosylcobinamide-GDP Co -[ -(adenin- SAM glutathione bifunctional UDP- cobS biosynthesis from a tetrahydrofolate aminomethyltransferase nicotinate-nucleotide a (2E)-oct-2-enoyl-[acp] succinate--CoA ligase inorganic GlpE: glpE RimO: rimO synthetase: ECTO60_RS05040 transpeptidase: glutamate- phosphatase Cca: cca mutY dihydroneopterin β 5-hydroxybenzimidazole NaMN NAD(+) α α methenyltetrahydrofolate formyltetrahydrofolate lipopolysaccharide I/protease I/ ammonium glucosidase: ATPase 9-yl)]-Co - biosynthesis sugar hydrolase/ Co -[ -(5- adenosylcobinamide-GDP nicotinamide nicotinate-nucleotide-- beta-ketoacyl-ACP subunit beta: sucC ECTO60_RS22015 sulfurtransferase: [+ 2 isozymes] ornithine phosphate mrcB 2-methyladenine triphosphate 2'- protoheme nicotinate adenine dinucleotidesynthetase: nadE NMN GcvT: gcvT adenylyltransferase: a [biotin carboxyl- lysophospholipase D-glucopyranose 6-phosphate diphosphatase: -cysteine 2',3'-cyclic-nucleotide adenosylcobamide methoxybenzimidazolyl) mononucleotide dimethylbenzimidazole menaquinol-7 biosynthesis enoyl-ACP core heptose(II) synthase II: fabF sseA argininosuccinate ECTO60_RS11080 succinate nicotinate-nucleotide-- protoheme IX 5'-nucleotidase: benzimidazole [+ 2 isozymes] nadD carrier protein]-L-lysine ECTO60_RS22015 carbamoyltransferase: a [ribosomal D-ribofuranose ligase: gshA 2'-phosphodiesterase: an apurinic site L-homocysteine 1-butanal sulfite pyruvate epimerase: folX 5'-phosphate methionine ]-Coβ-adenosylcobamide bifunctional protoporphyrin IX phosphoribosyltransferase: kinase RfaY: rfaY L1: tesA Carboxylate Degradation phosphate synthase: argG a 2,3,4-saturated triphosphate coenzyme F -A nicotinate-nucleotide-- ECTO60_RS18270 nicotinate-nucleotide-- deamidase-related reductase beta-ketoacyl-ACP glucose-6-phosphate argF 5'-deoxyadenosine an unsulfurated 2'-deoxyguanosine 5-phosphate 390 dATP predicted dimethylbenzimidazole glutathione- farnesyltransferase: cys glu bifunctional biotin- succinyl-CoA 2-oxoglutarate hydrogen sulfide thiocyanate sulfite met protein S12]-3- hypoxanthine cpdB adenine within DNA 7,8-dihydromonapterin adenosylcobalamin/ dimethylbenzimidazole adenosyltransferase: metK nicotinate-nucleotide 5'-phosphate formyltetrahydrofolate methylenetetrahydrofolate protein YfaY: cobT 1,4-dihydroxy- FabI: fabI glucosyl-(heptosyl) synthase I: fabB acyl-CoA isomerase: L-citrulline [sulfur carrier] fatty acyl-[acp] a peptidyl- an uncharged D-glucopyranose phosphoribosyltransferase: glutaredoxin cyoE bifunctional dimethylbenzimidazole deferrochelatase/ phosphate methylsulfanyl- D-glucopyranose 2+ ABC 2+ triphosphate deformylase: purU dehydrogenase/ -Kdo -lipid A- -[acetyl-CoA- thioesterase aminoacyl-[tRNA] tRNA γ-L-glutamyl-(S)- 3'-AMP Mn Mn alpha-ribazole phosphoribosyltransferase: adenylyltransferase: adenosylcobalamin/ folate polyglutamylation ECTO60_RS07850 2-naphthoate 3 2 ECTO60_RS23225 89 6-phosphate cobT redox reactions ferroheme o metallophosphatase/ phosphoribosyltransferase: peroxidase EfeB: efeB 1,4-dihydroxy- carboxylase] ligase/ superpathway of N-acetylneuraminate degradation L-aspartate transporter phosphatase: cobT nadD alpha-ribazole methenyltetrahydrofolate an octanoyl-[acp] bisphosphate a (7Z)-3-oxotetradec-7-enoyl-[acp] II: tesB L-ascorbate 2-methylcitrate cycle I pyruvate fermentation 2-aminobutanoate met SAH glutamate-- 5'-nucleotidase: cobT 2-naphthoate lipopolysaccharide 1,6- a 2,3,4-saturated of Mn2+ ECTO60_RS17565 glutathione phosphatase: cyclohydrolase FolD: folD ferrochelatase: 5-methylbenzimidazole ribotide phosphate biotin operon F6P degradation I to acetate II 2-methyladenine ribotide phosphate α α cysteine ligase: ECTO60_RS23700 benzimidazole ribotide phosphate polyprenyltransferase: 7 fatty acid Co -[ -(adenin- a tetrahydrofolate ECTO60_RS18295 beta-ketoacyl- galactosyltransferase: 3-oxo-cis-∆ - repressor BirA: birA N-acetylneuraminate (bacterial, anaerobic) ECTO60_RS17910 NaMN nicotinamide β ECTO60_RS17565 NaMN menA sedoheptulose propanoate core a peptidoglycan dimer (meso α N-acetyl-D- UDP-N-acetyl- GMP-N-ε-(N-α-acetyl guanosine a trans-delta2- N-acetyl-α- + + 7-yl)]-Coβ- NAD bifunctional 1-( -D Coα-[α-(5- 10 waaB 2-oxoglutarate 6-phosphofructokinase: pfkA an L-1- an [HPr]- phosphoenol -D-glucose Na RS26030 Na D-threo-7,8- 5-hydroxybenzimidazole ribotide phosphate 5'-methylthioadenosine/ an N -formyltetrahydrofolate adenosylcobinamide-GDP ACP synthase tetradecenoyl-[acp] a [biotin carboxyl-carrier L-ascorbate pyruvate GDP-α-D-glucose FMN NAD(P)H H + glutamate- ribofuranosyl) adenosylcobinamide-GDP protoheme demethylmenaquinol-7 bisphosphate bypass class II fructose- N-acetylneuraminate conversion of succinate to propanoate oligosaccharide- -diaminopimelate containing) 6-phosphate glucosamine α-D-glucosamine lysine methyl ester) 2',3'-cyclic a PII protein 4-hydroxy-L-threonine a tRNA precursor cis-delta21- D-muramoyl- dihydroneopterin adenosylcobamide phosphorylation and 5-methyltetrahydropteroyltriglutamate- S-adenosylhomocysteine nicotinamidase/ methoxybenzimidazolyl) ribazoletransferase: cobS II: fabF reductase: fabG 6 dehydrogenase E1 6-phosphofructokinase 6-phosphate phosphatidylethanolamine L-histidine pyruvate adenosylcobinamide-GDP a reduced ferroheme i serine bifunctional lipopolysaccharide protein]-N -biotinyl-L-lysine propionate- pyruvate Aromatic Compound Degradation -cysteine nicotinamide β ribazoletransferase: cobS bisphosphatase: glpX lyase: nanA L-ascorbate lipid A (E. coli 5'-phosphoramidate monophosphate UTP C40:2-[acp] L-alanine(1-) transhydrogenation adenosylcobinamide-GDP - homocysteine S- nucleosidase: mtnN pyrazinamidase: ]-Co -adenosylcobamide hydroxymethyltransferase: beta-ketoacyl- 3-alpha- D-sedoheptulose component: sucA II: pfkB -CoA dehydrogenase complex fused tRNA bifunctional 3- ribazoletransferase: cobS dihydromonapterin glutaredoxin ligase: gshA tetrahydrofolate Coα-[α-(5-methylbenzimidazolyl)]- bifunctional a (3R,7Z)-3-hydroxytetradec- N-acetylneuraminate 6-phosphate K-12 core type) + ribazoletransferase: cobS methyltransferase: metE pncA α α β galactosyltransferase: cyclopropane fatty acid 7-phosphate succinyl-CoA serine-type poly-beta-1,6 nucleotidyltransferase/ hydroxydecanoyl- preQ preQ reductase: folM NAD nicotinate Co -[ -(benzimidazolyl)]-Co - ECTO60_RS06500 synthase/ 10 demethylmenaquinone ACP synthase 7-enoyl-[acp] 2-oxoglutarate ligase: prpE dihydrolipoyllysine- phosphoenolpyruvate- alpha,alpha- NADPH- 0 RS01290 0 α α glutaredoxin thiamine an N - Coβ-adenosylcobamide 5'-phosphate DHAP β-D-fructose 1,6-bisphosphate lyase: lactonase: methylmalonyl- phenylacetate purine nucleoside low-specificity preQ preQ Co -[ -(2-methyladenin-9-yl)]-Co methionine synthase: metH L-homocysteine S-ribosyl-L-homocysteine phosphoribosyltransferase: adenosylcobamide 5'-phosphate I: fabB waaO (CFA) biosynthesis sedoheptulose- dehydrogenase residue 4-hydroxyphenylacetate 3-phenylpropanoate and 3-(3- cinnamate and 3-hydroxycinnamate chlorpyrifos degradation paraoxon degradation -protein D-Ala-D-Ala trehalose- N-acetyl-D- dependent FMN 2',3'-cyclic bifunctional ribonuclease D: ACP dehydratase/ N-acetylmuramoyl- 1 1 NAD(+) α α guanylyl molybdenum dihydrofolate methyltransferase/2- 7 [+ 4 isozymes] β-adenosylcobamide 5'-phosphate 5,6,7,8- 2: grxB Co -[ -(5-hydroxybenzimidazolyl)]- γ-L-glutamyl- salvage I formyltetrahydrofolate NAD phosphorylation 3-hydroxy cis ∆ - a [biotin carboxyl-carrier-protein ECTO60_RS04150 ulaG CoA mutase: degradation I (aerobic) degradation glucosamine phosphoramidase: uridylyltransferase/ L-threonine L-alanine amidase: acyl carrier protein metabolism pncB bis(guanylyl molybdenum a 5,10- synthase: folC adenosylcobalamin/alpha- galactosyl-glucosyl- 7-phosphate E1 component: 3-keto-L-gulonate acetyltransferase: aceF hydroxyphenyl)propanoate degradation degradation to 2-hydroxypentadienoate phosphoethanolamine phosphotransferase: ptsP carboxypeptidase: phosphate reductase: ssuE phosphodiesterase/ ECTO60_RS10730 trans-2- kinase: nadK β cofactor biosynthesis adenosylcobalamin/alpha- methoxy-6-polyprenyl- 6 a [phospholipid] cis class II fructose- ECTO60_RS04715 tetrahydromonapterin [+ 2 isozymes] hydroxyferroheme i Co -adenosylcobamide 5'-phosphate L-cysteine lipoate biosynthesis demethylmenaquinol- bifunctional and dephosphorylation ribazole phosphatase: (heptosyl) -Kdo - tetradecenoyl-[acp] dimer]-N -biotinyl-L-lysine propanoyl-CoA transferase: dacC synthase: hinT 2' nucleotidase/ uridylyl-removing aldolase: ltaE decenoyl-ACP ECTO60_RS16385 adenosylcobalamin/alpha- + cofactor) biosynthesis a 3-oxodecanoyl-[acp] 3 2 kinase: pfkA ECTO60_RS23055 triose-phosphate N-acetyl-D-mannosamine 6-phosphate acetyl-CoA synthase: otsA a protein with NADP thiamine nicotinate MoO - and incorporation I ribazole phosphatase: methylenetetrahydrofolate 1,4-benzoquinol dehydratase: fabZ -olefinic fatty acid bisphosphate aldolase: fbaA phenylacetate (4-hydroxyphenyl) chlorpyrifos paraoxon [+ 3 isozymes] NAD(P)H-flavin adenosylcobalamin/alpha- glutathione 2 9 biosynthesis tetrahydrofolate ECTO60_RS17565 lipid A-bisphosphate cyclopropane fatty 3-phenylpropanoate cinnamate ECTO60_RS16640 pgaC phosphatase Cca: cca protein GlnD: glnD isomerase: fabA [+ 3 isozymes] predicted ribazole phosphatase: a holo acyl- reduced L- thiamine MoO - bifunctional + methylase UbiE: ubiE acetyl-CoA D-sedoheptulose isomerase: tpiA acetate phosphotriesterase- [+ 3 isozymes] reductase: molybdopterin ECTO60_RS17565 2 synthase/ NAD N-acetylmannosamine 3-keto-L- phosphate 3-(3-hydroxyphenyl)propanoate a cis,cis-delta3,21- ECTO60_RS17565 carrier protein Re/Si-specific ribazole phosphatase: demethylmenaquinol- S-ribosylhomocysteine synthase: all-trans- a tetrahydrofolate Coα-[α-(5-methylbenzimidazolyl) 3-ketoacyl-ACP UDP-D- a (2E,7Z)-tetradeca- acyl phospholipid 2-methylcitrate [+ 2 isozymes] 2',3'-cyclic-nucleotide a nucleoside 5'- ABC cysteine residues kinase: cofactor molybdenum cofactor α α molybdopterin tetrahydrofolate carboxylase 1,7-bisphosphate gulonate-6- related protein: an [HPr protein]- α,α-trehalose N-α-acetyl lysine ECTO60_RS24195 glycolaldehyde a tRNA Co -[ -(benzimidazolyl) dihydrofolate β glucose:(glucosyl) synthase: kinase: synthase: prpC acetyltransferase: pta phosphotriesterase- π gly C40:2-[acp] D-ribose D-ribose Coα-[α-(2-methyladenin-7- NAD(P)(+) ECTO60_RS17565 6 biosynthesis I lyase: luxS gshB thiK tetrahydropteridine recycling an octanoyl-[acp] nonaprenyl 1,4-dihydroxy- cofactor ]-Co -adenosylcobamide menaquinol-7 reductase: 2,7-dienoyl-[acp] carboxyl transferase acetyl-CoA (R)-methylmalonyl- ECTO60_RS01755 N -phospho- pyruvate a peptidoglycan with poly-β-1,6- UDP GMP 2'-phosphodiesterase: monophosphate N-acetyl-D- transporter guanylyltransferase β bis(molybdenum synthase/ α D-glyceraldehyde 3-phosphate phosphate propanoyl-CoA phenylacetyl-CoA (3,4-dihydroxyphenyl) GDP 6-phosphate methyl ester a uridylylated α α thiamine lipoyl(octanoyl) diphosphate 2-naphthoate ]-Co -adenosylcobamide synthase: folC ECTO60_RS22120 LPS -1,3- a [phospholipid]ECTO60_RS11445 ECTO60_RS04155 phosphate CoA related protein: lipid A-core- N-acetyl-D- cpdB ala muramate of D-ribose yl)]-Coβ-adenosylcobamide transhydrogenase: Co -[ -(5-hydroxybenzimidazolyl) all-trans- glutathione MobA: mobA cofactor) dihydrofolate subunit alpha: accA carboxylase sedoheptulose ATP (2S,3S)-2- acetate 3-(3-hydroxy- 3-hydroxycinnamate phosphotriesterase: a 1,2-diacyl- L-histidine D,D cross-links (meso- D-ala PII protein ferroheme a 1,4-dihydroxy- transferase an N 10 - Re/Si-specific glucosyltransferase: enoyl-ACP decarboxylase acetyltransferase: (2E)-3-(5,6- ECTO60_RS01755 4'-phosphopantetheinyl pntA pntB ]-Coβ-adenosylcobamide hexaprenyl phosphate NADP + NAD(+) a (3R)-3- biotin carboxylase fatty acid containing bisphosphate biosynthesis type I glyceraldehyde- N-acetyl-D-mannosamine methylcitrate phenyl)propionate/ 3-(5,6-dihydroxycyclohexa- phosphoethanolamine diaminopimelate containing) glucosamine FMNH NAD(P) + 3'-GMP a 4a-hydroxytetrahydropteridine synthase: mobA synthase: folC acetyl-CoA UlaD: ulaD ECTO60_RS09320 sn-glycerol 2 menaquinol-8 biosynthesis ACP 2-naphthoate molybdopterin- LipB: lipB 1,4-dihydroxy- bis(molybdenum formyltetrahydrofolate NAD(P)(+) waaO reductase FabI: fabI cyclopropane ECTO60_RS07625 dihydroxycyclohexa- choline RS19010 choline transferase: diphosphate thiamine- a [lipoyl-carrier protein] phosphatase: kinase: hydroxydecanoyl-[acp] subunit: accC aldolase: fbaA 3-phosphate 6-phosphate 2-methylcitrate 3-hydroxycinnamic 1,3-dien-1-yl)propanoate phosphotriesterase: (hep I) phosphodiesterase: NADPH guanine cofactor) a 5,10- transhydrogenase: galactosyl-(glucosyl) carboxylase, 3-keto-L- 1,3-dien-1-yl) diethylthiophosphate ECTO60_RS24945 phosphate 6 2-naphthoate phoA dehydrogenase: gap dehydratase: acid hydroxylase: 3-hydroxy-trans- ECTO60_RS09320 acpH acyl carrier N -octanoyl-L-lysine methylenetetrahydrofolate nadK -(heptosyl) -Kdo - carboxyltransferase N-acetylmannosamine- acetyl phosphate 2-(1,2-epoxy-1,2- 1,4-dihydroxy- dinucleotide polyprenyltransferase: cytidylyl molybdenum molybdenum cofactor pntA pntB bifunctional 3- 2 3 2 a (7Z)-tetradec-7-enoyl-[acp] ADP gulonate-6- 2-hydroxy-5- cinnamate prop-2-enoate demethylmenaquinol-8 [+ 2 isozymes] protein activation kinase: thiL subunit beta: accD D-erythrose prpD dihydrophenyl) ECTO60_RS18880 β a 2'- GDP-α-D- 2-naphthoate a 6,7-dihydropteridine biosynthesis lipoyl guanylyltransferase hydroxydecanoyl- lipid A-bisphosphate DHAP 13-DPG 6-phosphate phosphate carboxymethylmuconate hydroxylase: core an L-1- a single D-glucopyranose α trimethylamine trimethylamine N-acetyl- - a PepB a trans-delta2- bifunctional menA cofactor biosynthesis 4-phosphate F0F1 ATP ADP- -D-glucose a reduced c- a reduced a ribonucleoside γ serine serine thiamine guanylyl synthase: lipA lipopolysaccharide beta-ketoacyl-ACP a [carboxyl-carrier protein dimer]- 2-epimerase: cis-2- propionate kinase: tdcD acetyl-CoA diethylphosphate 4-nitrophenol oligosaccharide- 6-phosphate N-oxide N-oxide neuraminate deoxyribonucleoside formate aminopeptidase -L-glutamyl-(S)- gly cis-delta15- mannose polyprenyltransferase: an apo acyl- protein B: mobB MoO - MobA: mobA ACP dehydratase/ long-chain fatty synthase: decarboxylase semialdehyde ECTO60_RS18880 phosphatidylethanolamine stranded DNA type cytochrome TorC protein [DNA] ATP triphosphate demethylmenaquinone diphosphate oxygen-insensitive 2 glucosyltransferase 6 methylaconitate 5'-triphosphate 2-aminobutanoate RS00870 molybdenum a [lipoyl-carrier bis(guanylyl + synthase II: fabF N -carboxybiotinyl-L-lysine ECTO60_RS02540 2,3-DHP lipid A (E. coli cob(II)alamin substrate C34:2-[acp] an apo acyl- menA carrier protein molybdopterin NADP trans-2- acid activation atpI atpB phosphoglycerate kinase: UlaD: ulaD [+ 3 isozymes] D-gluconate 2-hydroxy-5- bifunctional 3- methyltransferase/2- 4'-phosphopantetheinyl NAD(P)H cofactor protein]-N 6 -[(R)- demethylmenaquinol-9 RfaJ: rfaJ N-acetyl-D-glucosamine bifunctional diethylphosphate K-12 core type) thr thr molybdopterin) decenoyl-ACP beta-ketoacyl-ACP atpE atpF ECTO60_RS04680 L-xylulose carboxymethylmuconate 2,3-dihydroxy- N-acetylneuraminate hydroxydecanoyl- GDP-mannose methoxy-6-polyprenyl- carrier protein transferase: nitroreductase: nfsB cofactor molybdenum cofactor galactosyl-(glucosyl) degradation 2,3-dihydroxyphenylpropionate/ exodeoxyribonuclease alpha,alpha- serine serine dihydrolipoyl]-L-lysine cofactor isomerase: fabA synthase I: fabB a long-chain 6-phosphate 5-phosphate aconitate acetate 2-oxepin-2(3H)- semialdehyde trans-cinnamate trimethylamine- trimethylamine- lyase: DNA anaerobic glutathione ACP dehydratase/ mannosyl hydrolase: 1,4-benzoquinol demethylmenaquinol-6 ECTO60_RS24945 cytidylyltransferase: -(heptosyl) -Kdo - atpH atpA 2, 3-dihydroxicinnamic VII small subunit: xseB trehalose- aminopeptidase 3 3 2 fatty acid hydratase 2/2- N-oxide ethanolamine ribonucleoside- synthase: ECTO60_RS08810 RS05425 a 5,6,7,8-tetrahydropteridine cytidylyl mocA 3-hydroxyacyl- acyl-CoA atpG 3-phospho-D-glycerate N-acetylglucosamine- D-gluconate ylideneacetyl-CoA dehydrogenase: gabD 2,3- phosphoethanolamine phosphate N-oxide ECTO60_RS04150 polymerase PepB: pepB trans-2- methylase UbiE: ubiE [+ 2 isozymes] lipid A-bisphosphate a (9Z)-3-oxohexadec-9-enoyl-[acp] L-ribulose-5- methylisocitrate acid 1,2-dioxygenase: phenylethylamine exodeoxyribonuclease utilization cob(I)yrinic triphosphate thr thr a holo acyl- molybdenum synthetase atpD atpC 6-phosphate gluconokinase: transferase: reductase reductase III subunit gshB decenoyl-ACP menaquinol-8 ACP lipopolysaccharide phosphate 3- 5-carboxymethyl-2- ECTO60_RS18875 dihydroxycinnamate VII large subunit: xseA synthase: otsA N-acetylneuraminate serine serine 2,3-bisphosphoglycerate- 2,3-diphosphoglycerate- dehydratase: acnB degradation I ECTO60_RS16640 TorA: torA TorA: torA delta': holB acid a,c-diamide reductase: nrdD isomerase: fabA carrier protein cofactor dehydratase heptosyltransferase FdrA: fdrA deacetylase: nagA epimerase: gntK hydroxymuconate dioxygenase: lyase: nanA 3-ketoacyl-ACP flagellum- independent dependent D-gluconate (2Z,4E)-2-hydroxy-6- adenosyltransferase a cis,cis-delta3,15- D-mannose RS04995 FabZ: fabZ N-acetylglucosamine- (2R,3S)-2- [+ 3 isozymes] [+ 11 isozymes] a proteinogenic family protein: reductase: [+ 3 isozymes] specific ECTO60_RS22200 D-malate 3-oxo-5,6- oxonona-2,4-diene-1,9-dioate ECTO60_RS18875 2-phenylethylamine α,α-trehalose EutT: eutT ophthalmate GDP a long-chain phosphoglycerate phosphoglycerate methylisocitrate 6-phosphate a ribonucleoside a single-stranded a 2'- a peptide C34:2-[acp] thr thr ECTO60_RS00450 ATP 6-phosphate degradation didehydrosuberyl- (2Z,4E,7E)-2- 6-phosphate N-acetyl-β-D- amino acid ECTO60_RS22120 fatty acyl-CoA mutase: gpmM mutase: gpmA L-ribulose-5- 2-hydroxy-6-ketonona-2,4- 5'-monophosphate oligodeoxyribonucleotide ADP an oxidized c- trimethylamine an oxidized trimethylamine deoxyribonucleoside a (2E)-dec-2-enoyl-[acp] core oligosaccharide- deacetylase: nagA hydroxy-6-oxonona- parathion degradation lipid A-core- mannosamine pyruvate synthase phosphate 3- CoA semialdehyde a 1,2-diacyl- type cytochrome TorC protein [DNA] Aminoacyl-tRNA Charging lipid A (E. coli K-12 a (3R,9Z)-3-hydroxyhexadec- methylisocitrate (R)-malate (3E,5R)-5-carboxy-2- dienedioate hydrolase: 2,4,7-triene-1,9-dioate pyrophosphoethanolamine 5'-triphosphate FliI: fliI 2-phospho-D-glycerate epimerase: phenylacetaldehyde sn-glycerol adenosylcobalamin core type) (no GlcNAc) 9-enoyl-[acp] D-glucosamine 6-phosphate lyase: prpB oxohept-3-enedioate ECTO60_RS18870 2-hydroxy-6- ATP ECTO60_RS00645 gln enoyl-ACP bifunctional 3- 9 parathion glutaminyl-tRNA lipopolysaccharide 3-hydroxy cis ∆ - phosphopyruvate (2Z)-2-hydroxypenta-2,4-dienoate oxononadienedioate/ tRNA charging reductase hydroxydecanoyl- L-ribulose 5- 3-oxo-5,6- biosynthesis via transamidation heptosyltransferase hexadecenoyl-[acp] hydratase: pyruvate succinate pyruvate 2-hydroxy-6- α β a 2'- γ FabI: fabI ACP dehydratase/ phosphate didehydrosuberyl- an L-1- an E. coli UDP-N-acetyl- -D-muramoyl-L- a [ThiI sulfur- sn-glycero-3-phospho- trimethylamine luteolin 7-O-[ -D- L-alanyl- -D- a CDP- lysine within family protein: dehydratase: fabZ ECTO60_RS05500 2-keto-4-pentenoate oxononatrienedioate phosphotriesterase- a uracil in tRNA a reduced triphosphate (S)-NADHX (R)-lipoate CoA (4Z)-2-oxohept- phosphatidylethanolamine osmoregulated alanyl-γ-D-glutamyl-meso-2,6- carrier protein]- N-(arachidonoyl) N-oxide glucosyluronate-(1,2)-β- deoxyribonucleoside [DNA] glutamyl-L-lysyl- a peptide diacylglycerol gcv protein H trans-2- ECTO60_RS00450 α L-ribulose-5- hydrolase: related protein: TorY protein Phe Gly Trp Ala His Met Met Arg asp Thr Tyr Asn Gln Leu Cys Pro Ile Lys -D-glucosamine 6-phosphate hydratase: mhpD phenylacetate 5'-triphosphate glu phe a tRNA gly a tRNA trp a tRNA a tRNA ala his a tRNA elongator tRNA met initiator tRNA met arg a tRNA tRNA asp thr a tRNA tyr a tRNA asn tRNA gln a tRNA leu a tRNA cys a tRNA pro a tRNA ile a tRNA lys a tRNA decenoyl-ACP a (2E,9Z)-hexadeca- phosphoenolpyruvate 4-enedioate periplasmic diaminopimeloyl-D-alanyl-D-alanine S-sulfanyl- ethanolamine D-glucosiduronate]-4'- D-alanyl-D-alanine bifunctional ADP- ser Val glu core oligosaccharide- phosphate 4- ECTO60_RS18870 ser a tRNA val a tRNA glu a tRNA a decanoyl-[acp] 2,9-dienoyl-[acp] ECTO60_RS01755 glucan (OPG) L-cysteine O-β-D-glucosiduronate dependent NAD(P)H- isomerase: fabA glucosamine- epimerase: CDP-diacylglycerol lipid A (E. coli (S)-4-hydroxy-2-oxopentanoate (2Z)-2-hydroxypenta- phosphotriesterase: inorganic hydrate dehydratase/ lipoate-- UDP pyruvate kinase: pyk araD phosphoethanolamine serine-type D-Ala-D-Ala glycerophosphodiester trimethylamine- DNA serine-type Xaa-Pro K-12 core type) enoyl-ACP phosphoenolpyruvate 6-phosphate trans-2,3- 2,4-dienoate ECTO60_RS09320 tRNA 4- triphosphatase: diphosphatase: protein ligase phenylalanine--tRNA glycine--tRNA tryptophan-- alanine--tRNA histidine--tRNA methionine--tRNA methionine--tRNA arginine--tRNA aspartate--tRNA threonine--tRNA tyrosine--tRNA asparagine-- glutamine--tRNA leucine--tRNA cysteine--tRNA proline--tRNA isoleucine-- lysine--tRNA ligase: lysS beta-ketoacyl- pyruvate kinase I: transferase: carboxypeptidase: dacC phosphodiesterase: glpQ N-oxide beta- polymerase D-Ala-D-Ala aminopeptidase: NAD(P)H-hydrate reductase FabI: fabI synthase: ppsA deaminase: nagB [+ 2 isozymes] dehydroadipyl-coA (4S)-4-hydroxy-2- 4-hydroxy-2-oxovalerate thiouridine(8) ECTO60_RS23820 LplA: lplA ligase: pheS pheT ligase: glyQ glyS tRNA ligase: trpS ligase: alaS ligase: hisS ligase: metG ligase: metG ligase: argS ligase: aspS ligase: thrS ligase: tyrS tRNA ligase: asnS serine--tRNA ligase: serS ligase: glnS ligase: leuS ligase: cysS ligase: proS tRNA ligase: ileS valine--tRNA ligase: valS lysine--tRNA ligase: lysS ACP synthase a (3Z)-dec-3-enoyl-[acp] ECTO60_RS11370 reductase glucuronidase: III subunit pepP ECTO60_RS03330 epimerase: gln D-xylulose oxoheptanedioate aldolase: dmpG ECTO60_RS16640 [+ 3 isozymes] glycerophosphodiester carboxypeptidase: an L-glutamyl- II: fabF glucosamine- synthase TorA: torA uidA delta': holB ECTO60_RS22350 Gln 4-nitrophenol phosphodiesterase: ugpQ dacC [tRNA ] 6-phosphate 5-phosphate pyruvate decarboxylation to acetyl CoA diethylthiophosphate [+ 2 isozymes] ThiI: thiI CMP a 1,2-diacyl- a [glycine-cleavage beta-ketoacyl- beta-ketoacyl- a palmitoleoyl-[acp] pyruvate acetaldehyde NADH asparagine Phe Gly Trp Ala His Met Met Arg asp Thr Tyr Asn ser Gln Leu Cys Pro Ile Val Lys Glu UDP-N-acetylmuramoyl-L- [+ 11 isozymes] [+ 3 isozymes] an L-phenylalanyl-[tRNA ] a glycyl-[tRNA ] an L-tryptophanyl-[tRNA ] an L-alanyl-[tRNA ] an L-histidyl-[tRNA ] an L-methionyl-[elongator tRNA ] an L-methionyl-[initiator tRNA ] an L-arginyl-[tRNA ] an L-aspartyl-[tRNA ] an L-threonyl-[tRNA ] an L-tyrosyl-[tRNA ] an L-asparaginyl-[tRNA ] an L-seryl-[tRNA ] an L-glutaminyl-[tRNA ] an L-leucyl-[tRNA ] an L-cysteinyl-[tRNA ] an L-prolyl-[tRNA ] an L-isoleucyl-[tRNA ] an L-valyl-[tRNA ] an L-lysyl-[tRNA ] an L-glutamyl-[tRNA ] deaminase: an E. coli osmoregulated a proteinogenic phosphate diphosphate sn-glycerol complex H protein] N synthase B: glutamyl-tRNA ACP synthase ACP synthase a [pyruvate dehydrogenase pyruvate (3S)- a 1,2-diacyl- γ a peptide oleate biosynthesis pyruvate ECTO60_RS24915 methyl parathion degradation periplasmic glucan with D-ala alanyl- -D-glutamyl-meso-2,6- a [ThiI sulfur- a 4-thiouracil β luteolin 7-O-β- 3-phosphate -[(R)-lipoyl]-L-lysine amidotransferase: I: fabB II: fabF 6 dehydrogenase hydroxyadipyl- acetaldehyde sn-glycerol an oxidized trimethylamine -D-glucuronate amino acid ECTO60_RS17405 IV (anaerobic) dehydrogenase complex E2 protein] N -lipoyl-L-lysine diaminopimeloyl-D-alanine carrier protein]- in tRNA anandamide sn-glycerol 3-phosphate D-diglucuronide L-alanyl-γ-D- ECTO60_RS24315 beta-ketoacyl-ACP pyruvate(acetyl-transferring) CoA succinate semialdehyde dehydrogenase (acetylating) phosphotidylethanolamine TorY protein [DNA] [+ 8 isozymes] beta-ketoacyl- dihydrolipoyllysine-residue F6P L-cysteine glutamyl-L- D-ala a 5-phosphooxy- a 3-oxododecanoyl-[acp] synthase II: fabF pyruvate , homodimeric : ECTO60_RS18860 methyl parathion substituent ACP synthase a (3R)-3- acetyltransferase: aceF 3-hydroxyadipyl- NADP-dependent diethylphosphate lysyl-D-alanine L-glutamyl- dehydrogenase type: aceE ammonium I: fabB hydroxydodecanoyl-[acp] palmitoleate 6-phosphofructokinase: CoA Gln 3-ketoacyl-ACP 3-hydroxyacyl- class II fructose- succinate- acetyl-CoA [tRNA ] an (11Z)-3-oxooctadec- acetyl-CoA pfkA complex dehydrogenase: a (5Z)-3-oxododec- ACP dehydratase pyruvate semialdehyde phosphotriesterase- Polyprenyl Biosynthesis reductase: 11-enoyl-[acp] bisphosphatase: dihydrolipoyllysine- fadJ UDP-N-acetyl- undecaprenyldiphospho- a 1-acyl-2-lyso- D-threo-7,8- all-trans- cytidine 2',3'-cyclic a [protein chain a [protein] N- 2''-O-acetyl- oxaloacetate 6-phosphofructokinase dehydrogenase dehydrogenase related protein: a 5-L-glutamyl- acetoacetate S-methyl-L- glutamyl-tRNA ECTO60_RS22120 5-enoyl-[acp] FabZ: fabZ glpX residue α-D-glucosamine N-acetylmuramoyl-L- an amino acid phosphatidylethanolamine succinyl-CoA dihydroneopterin dodecaprenyl 1,4-dihydroxy- monophosphate (R)-β-lysine elongation factor L-homocysteine terminal-formyl- asp O-ureido-L- ADP-ribose thr 3-ketoacyl-ACP II: pfkB complex I: gabD ECTO60_RS01755 [peptide] methionine amidotransferase: ∆ 5 a (2E)-dodec-2-enoyl-[acp] acetyltransferase: 3-oxoadipyl-CoA alanyl-γ-D-glutamyl-meso diphosphate 2-naphthoate fused tRNA EF-P]-L-lysine 34 L-methionine homoserine polyisoprenoid biosynthesis (E. coli) a (3R)-3- 3-oxo-cis- - reductase: dihydrolipoyllysine- phosphotriesterase: L-threonine 3- ECTO60_RS24315 Amino Acid Biosynthesis nucleotidyltransferase/ geranyl superpathway of L- hydroxydodecanoyl-[acp] dodecenoyl- citrate (Si)-synthase: gltA β-D-fructose 1,6-bisphosphate aceF succinate -2,6-diaminopimeloyl- O-acetyl-ADP- superpathway of aromatic amino acid biosynthesis superpathway of L-tryptophan biosynthesis superpathway of L-lysine, L-threonine and L-methionine biosynthesis I L-histidine biosynthesis superpathway of L- superpathway of L- superpathway of L-homoserine and L-methionine biosynthesis superpathway of L-aspartate bifunctional 3- ECTO60_RS22120 pyruvate residue ECTO60_RS09320 multifunctional acyl- acyl CoA:acetate/ bifunctional dehydrogenase: diphosphate isoleucine biosynthesis I superpathway of branched chain amino acid biosynthesis [acp] malate dehydrogenase D-alanyl-D-alanine gamma- 2',3'-cyclic homocysteine S- phenylalanine biosynthesis tyrosine biosynthesis and L-asparagine biosynthesis [+ 2 isozymes] dehydrogenase acetyltransferase: CoA thioesterase dihydroneopterin 1,4-dihydroxy- elongation peptide deformylase: ribose deacetylase: ECTO60_RS00480 an L-glutaminyl- 3-hydroxyacyl- hydroxydecanoyl- a (3R,11Z)-3-hydroxyoctadec- a [pyruvate dehydrogenase 3-ketoacid CoA phosphodiesterase/ argininosuccinate IPP biosynthesis reductase: (quinone): mqo a [pyruvate dehydrogenase E2 aceF glutamyltransferase: 2-naphthoate factor P--(R) methyltransferase: ECTO60_RS14845 Gln oxaloacetate D-erythrose D-erythrose oxaloacetate ACP ACP dehydratase/ 11-enoyl-[acp] complex E2 protein] N 6 -S- undecaprenyldiphospho- I/protease I/ transferase: aldolase/7,8- ECTO60_RS02195 synthase: argG L-threonine [tRNA ] phosphoenolpyruvate PRPP D-erythrose phosphoenol D-erythrose phosphoenol pyruvate fabG malate dehydrogenase: mdh 6 4-nitrophenol ECTO60_RS01420 2' nucleotidase/ mmuM 4-phosphate 4-phosphate asp thr class II fructose- L-ascorbate degradation protein] N -dihydrolipoyl-L-lysinedihydrolipoyllysine- succinyl-CoA dimethylthiophosphate lysophospholipase dihydroneopterin polyprenyltransferase: -beta-lysine isopentenyl- IPP aspartate/ glu dehydratase trans-2- 3-hydroxyacyl- acetyldihydrolipoyl-L-lysine muramoylpentapeptide beta-N- ECTO60_RS22135 phosphatase Cca: cca dehydrogenase: 4-phosphate pyruvate 4-phosphate pyruvate a (3R,5Z)-3- acetyl-CoA malate dehydrogenase: II (bacterial, aerobic) menA ligase: epmA (2E,6E)- tyrosine/aromatic 3-deoxy-7- aspartate/ ATP acetolactate FabZ: fabZ decenoyl-ACP bisphosphate residue acetylglucosaminyltransferase: L1: tesA [+ 2 isozymes] epimerase: folB yiaY diphosphate bifunctional aspartate fumarate hydroxydodec- ACP dehydratase malateECTO60_RS12135 synthase A: aceB an α-(5-L- 2',3'-cyclic-nucleotide an N-terminal L- acetate ADP-D-ribose farnesyl 3-deoxy-7- tyrosine/aromatic phosphoribosyltransferase: threonine isomerase: fabA superpathway of phospholipid biosynthesis I (bacteria) aldolase: fbaA acetyltransferase: murG aminoacetone Delta-isomerase: aminotransferase: phosphoheptulonate 3-deoxy-7- 3-deoxy-7- kinase/homoserine synthase: ilvN ilvI a (2E)-dodec- 5-enoyl-[acp] FabZ: fabZ 2'-phosphodiesterase: formate canavaninosuccinate aminotransferase: ammonia-lyase, aspartate/ malate synthase G: glcB L-ascorbate aceF glutamyl)- a peptide [a protein chain met methionyl-[protein] ECTO60_RS04860 diphosphate ECTO60_RS15340 synthase AroG: aroG phosphoheptulonate hisG [+ 4 isozymes] 2-enoyl-[acp] 3-hydroxy cis (S)-malate citrate phosphoheptulonate phosphoheptulonate dehydrogenase I: thrA biosynthetic: ilvA a (2E,11Z)-octadeca- triose-phosphate amino acid sn-glycero-3- 6-(hydroxymethyl) glycolaldehyde DMK-12 cpdB synthase: ispA synthase AroG: aroG ECTO60_RS15340 tyrosine/aromatic aspartate ∆ 5 a (3Z)-dodec-3-enoyl-[acp] lipid II (meso UDP a carboxylate acetoacetyl-CoA succinate elongation factor geranyl asp [+ 2 isozymes] 1-(5-phospho- synthase AroG: aroG synthase AroG: aroG [+ 2 isozymes] -dodecenoyl- DHAP isomerase: tpiA phosphoethanolamine -7,8-dihydropterin (S)-2-acetolactate aminotransferase: ammonia- glycine biosynthesis II enoyl-ACP 2,11-dienoyl-[acp] diaminopimelate containing) 3'-cmp EF-P]-N-(β-L- DMAPP 3-deoxy-D-arabino- [+ 2 isozymes] β-D-ribosyl)-ATP bifunctional [acp] bifunctional aconitate D-glyceraldehyde 3-phosphate DHAP diphosphate [+ 2 isozymes] [+ 2 isozymes] reductase beta-ketoacyl- Polymeric Compound Degradation 34 heptulosonate asp threonine ECTO60_RS15340 lyase: aspA NAD(P)H-dependent hydratase 2/2- L-dehydro-ascorbate lysyl)-L-lysine bifunctional bifunctional L-aspartyl-4-phosphate ketol-acid a [glycine-cleavage FabI: fabI dehydratase: enoyl-ACP (2E,6E)- 7-phosphate 3-deoxy-D-arabino- ammonia-lyase/L- ACP synthase glycerol-3-phosphate type I aspartate kinase/ phosphoribosyl- 3-deoxy- reductoisomerase: 6 fabZ reductase FabI: fabI methylisocitrate acetyl-CoA oxalate degradation II farnesyl heptulosonate bifunctional 3-deoxy- complex H protein] N - II: fabF glyceraldehyde- glycogen degradation I homoserine 3-dehydroquinate D-arabino- serine ammonia- glycine cleavage system dehydrogenase: gpsA dehydratase: acnB muropeptide degradation 6 37 di-trans,octa-cis a thiocarboxylated cyclic an sn-glycero-3- all-trans- uridine 2'3'-cyclic β AMP cyclohydrolase/ D-arabino- ilvC aminomethyldihydrolipoyl- a dodecanoyl-[acp] chitin degradation III (Serratia) N -dimethylallyladenosine α + sn-glycerol 3-hydroxybenzoyl- D-gluconate luteolin 7-O- - diphosphate 7-phosphate aspartate kinase/ aspartate-semialdehyde asp a (2E,5Z)-dodeca- 3-phosphate a sulfurated UDP- -D-glucose FMN NADH H A ammonium H O H O heptulosonate heptulosonate lyase TdcB: tdcB aminomethyltransferase a (5Z)-3-oxo- class I fumarate hydratase: -undecaprenyl [SAMP] C- pyranopterin phospho-N-(acyl) H O undecaprenyl 1,4-dihydroxy- monophosphate 2 2 dehydrogenase synthase: aroB phosphoribosyl-ATP L-lysine aconitate hydratase in tRNA 2 GTP 3-phosphate CoA 6-phosphate D-glucuronide synthase: ispA homoserine dehydrogenase: asd (2R)-2,3-dihydroxy- 3,5-dienoyl-[acp] tetradec-5-enoyl-[acp] a cis-vaccenoyl-[acp] sn-glycerol 3-phosphate ECTO60_RS22635 dehydrogenase: oxalate a glycogen [sulfur carrier] 2-naphthoate CTP I: thrA 3-dehydroquinate diphosphatase HisIE: 7-phosphate 7-phosphate gly GcvT: gcvT AcnA: acnA dehydroascorbate L-alanyl-γ-D-glutamyl-meso- phosphate terminal glycine phosphate ethanolamine diphosphate fused tRNA 6-phosphogluconate dehydrogenase aspartate-semialdehyde 3-methylbutanoate (2Z)-2-aminobut-2-enoate asparagine glycine cleavage system gap chitin geranyl 3-dehydroquinate synthase: aroB [+ 2 isozymes] enoyl-ACP [+ 4 isozymes] (bicyclic form) 2,6-diaminopimeloyl-D-alanine nucleotidyltransferase/ phosphatase: yieH [+ 2 isozymes] ECTO60_RS08930 3-dehydroquinate 3-dehydroquinate synthase B: aminomethyltransferase beta-ketoacyl- (5Z)-3-oxo- glycogen NAD(P)H-flavin proofreading beta- diphosphate I: thrA dehydrogenase: dihydroxy-acid reductase 2',3'-cyclic glycerol-3-phosphate hydroxylamine β synthase: aroB synthase: aroB ECTO60_RS17405 GcvT: gcvT ACP synthase tetradec-5- glycerol-3-phosphate glycerol-3-phosphate fumarate cis-aconitate phosphorylase: muramoyltetrapeptide tRNA (N6-isopentenyl undecaprenyl- molybdopterin glycerophosphodiester 1,4-dihydroxy- fructose-1- L-aspartyl- type I 3- 3-dehydroquinate [+ 2 isozymes] 1-(5-phospho- - ECTO60_RS07520 dehydratase: ilvD FabI: fabI 13-DPG oxalyl-CoA GTPase: phosphodiesterase/ reductase: cytidylyltransferase: thioesterase glucuronidase: (2E,6E)- II: fabF enoyl-[acyl- adenosine(37)-C2)- phosphate glucose synthase phosphodiesterase: ugpQ 2-naphthoate reductase: priS phosphate/6- dehydroquinate D-ribosyl)-AMP aspartate- [+ 2 isozymes] 1-O-acyltransferase 1-O-acyltransferase ECTO60_RS01495 carboxypeptidase: ldcA ECTO60_RS21045 ECTO60_RS24195 EntH: entH uidA 4-phosphate 3-dehydroquinate 3-dehydroquinate laurate succinate dehydrogenase: bifunctional aconitate methylthiotransferase phosphotransferase: polyprenyltransferase: 2' nucleotidase/ ECTO60_RS19500 phosphogluconate farnesyl type I 3- L-aspartyl- L-aspartate 4-semialdehyde a [glycine-cleavage a [glycine-cleavage beta-ketoacyl- a (5Z)-dodec- carrier-protein] cis-vaccenate PlsB: plsB PlsB: plsB glyoxylate phosphoglycerate oxalyl-CoA maltodextrin γ catalytic subunit glycerophosphodiester [+ 5 isozymes] dehydratase: aroD bifunctional 3-methyl-2-oxobutanoate -ammonia ECTO60_RS17110 [(1->4)-β-N-acetyl- L-alanyl- -D-glutamyl- phosphatase Cca: cca NADPH- diphosphate aspartate- dehydroquinate 4-phosphate 2-iminobutanoate complex H protein] N 6 complex H protein] N 6 ACP synthase 5-enoyl-[acp] reductase: fabG hydratase 2/2- 2,3-dioxo-L-gulonate decarboxylase: MiaB: miaB wcaJ MoaE: moaE phosphodiesterase: glpQ menA phosphatase: yqaB phosphoribosyl- type I 3- type I 3- ligase: asnA long-chain- glycerol-3-phosphate glycerol-3-phosphate sdhA sdhC kinase: phosphorylase: D-glucosaminyl] meso-diaminopimelate dependent FMN methylisocitrate n 2',3'-cyclic-nucleotide hydroxylamine β-D-glucuronate synthase: ispA semialdehyde 3-dehydroshikimate dehydratase: aroD bifunctional aspartate -[(R)-lipoyl]-L-lysine -dihydrolipoyl-L-lysine I: fabB beta-ketoacyl- a (3R,5Z)-3-hydroxy- 1-O-acyltransferase 1-O-acyltransferase ECTO60_RS04680 ECTO60_RS07275 malP chitin 3-hydroxybenzoate D-gluconate luteolin AMP cyclohydrolase/ dehydroquinate dehydroquinate fatty-acid-- 3-dehydro-L-gulonate -(1->4)-2- + reductase: ssuE CDP-glycerol aspartate- 2-isopropylmalate branched-chain- 2-iminobutanoate/ succinate dehydrogenase/ dehydratase: acnB murein tripeptide 6 phosphate H 2'-phosphodiesterase: dehydrogenase: kinase/homoserine asn ACP synthase PlsY: plsY PlsY: plsY 2-methylsulfanyl-N - α-D-glucopyranosyl- UMP GDP (2E,6E)-farnesyl shikimate 3-dehydroshikimate semialdehyde phosphoribosyl-ATP dehydratase: aroD dehydratase: aroD 2-iminopropanoate CoA ligase tetradec-5-enoyl-[acp] 2-dehydrogenase: (acetylamino)-2- amidase MpaA: mpaA an unsulfurated a [SAMP] C- sn-glycerol an N- asd superpathway of L-methionine biosynthesis (transsulfuration) dehydrogenase I: thrA synthase: leuA amino-acid fumarate reductase aconitate hydratase 3-phospho-D-glycerate formyl-CoA an α-limit dextrin 5'-deoxyadenosine dimethylallyladenosine 37 met diphosphoundecaprenol molybdopterin DMKH2-11 cpdB diphosphate diphosphatase HisIE: a 3-oxotetradecanoyl- FadD: fadD II: fabF (3R,5Z)-3- ECTO60_RS00685 bifunctional deoxy-D-glucono- [sulfur carrier] terminal glycine 3-phosphate acylethanolamine dehydrogenase: dehydrogenase: 3-dehydroshikimate 3-dehydroshikimate transaminase: ilvE deaminase: L-asparaginase iron-sulfur subunit: AcnA: acnA chitin degradation II (Vibrio) in tRNA 3'-UMP aspartate- shikimate ECTO60_RS08930 bifunctional aspartate [acp] [+ 3 isozymes] beta-ketoacyl- formyl-CoA--oxalate chitinase/ 1,5-lactone L-alanyl-D-glutamate Detoxification FMNH NAD + ydiB asd ECTO60_RS21930 hydroxy- ECTO60_RS22420 2,3- 2 dehydrogenase: β oxaloacetate kinase/homoserine (2S)-2-isopropylmalate 2: ansB octanoyl-[acyl-carrier a 1-acyl-sn-glycerol 3-phosphate a 1-acyl-sn-glycerol 3-phosphate isocitrate lyase: aceA 2,3-bisphosphoglycerate- 3-keto-L-gulonate limit dextrin α-1,6- (2E,6E)-farnesyl- octaprenyl- semialdehyde 1-(5-phospho- -D-ribosyl)- shikimate shikimate glycine cleavage system 3-ketoacyl-ACP ACP synthase tetradeca-5- diphosphoglycerate- CoA-transferase: lysozyme: shikimate ydiB aspartate- dehydrogenase II: asparaginase: lauroyl-CoA protein] biosynthesis succinate D-threo-isocitrate independent glucohydrolase: chitin L-Ala-D/L-Glu diphosphate- diphosphate dehydrogenase: 5-[(5-phosphoribosylamino) dehydrogenase: val 2-oxobutanoate aminomethyltransferase reductase: I: fabB enoyl-[acp] dependent ECTO60_RS07270 chiA reactive oxygen species degradation semialdehyde dehydrogenase: aspartate/ 3-isopropylmalate ansA (mitochondria, yeast) 3-keto-L-gulonate phenylmercury ECTO60_RS07520 ECTO60_RS23710 phosphoglycerate glgX epimerase: α 32 an all-trans- a peptidoglycan a (1->4)- 3''-O-acetyl- specific synthase: methylideneamino]imidazole- ydiB ydiB GcvT: gcvT ECTO60_RS22120 dehydratase: fabZ acyl-CoA:1-acyl-sn- acyl-[acp]:1-acyl-sn- NADP-dependent phosphoglycerate bifunctional arsenate 8-oxo-(d)GTP detoxification I arsenate arginine dependent β [2/3-O-acetyl- -L-fucosyl]- di-trans,octa-cis core a cytosine an [L-cysteine 1-(oleoyl)-sn-glycero-3- all-trans- salicin 6- shikimate shikimate dehydrogenase: tyrosine/aromatic dehydratase: acetolactate a (7Z)-3-oxotetradec- ADP-forming mutase: gpmM kinase: lyxK formate [(1->4)-β-N-acetyl- ECTO60_RS12615 acetate degradation GDP- -L-fucose 1,4-dihydroxy- 1,4-dihydroxy- a tripeptide stachyose citrate ditrans,polycis- ECTO60_RS02685 4-carboxamide a (3R)-3- isocitrate dehydrogenase: succinate detoxification detoxification acid resistance (1->3)-β-D-glucopyranosyl- -undecaprenyl oligosaccharide- desulfurase]-S- phosphoethanolamine polyisoprenyl tridecaprenyl dimer (generic) phosphate α-D-glucan ADP-ribose L-aspartate 4- kinase ECTO60_RS07520 aminotransferase: leuC leuD synthase: ilvN ilvI asp [+ 4 isozymes] 7-enoyl-[acp] a (2E,5Z)-tetradeca- an acetoacetyl-[acp] glycerol-3-phosphate 2- glycerol-3-phosphate 2- succinate--CoA ligase mutase: gpmA a debranched a chitodextrin D-glucosaminyl] chitinase/ superoxide in tRNA L-homoserine n 2-naphthoate 2-naphthoate aconitate hydratase undecaprenyl- semialdehyde shikimate 1-(5-phosphoribosyl)-5- shikimate shikimate hydroxytetradecanoyl- 3-ketoacyl-ACP O-acyltransferase: plsC O-acyltransferase: plsC ECTO60_RS14395 3-keto-L-gulonate maltotetraose III (thioredoxin) mercuriphenyl II (glutaredoxin) diphosphoundecaprenol diphosphate lipid A (E. coli sulfanyl-L-cysteine diphosphate diphosphate AroL: aroL ECTO60_RS15340 [+ 4 isozymes] ∆ 7 2,5-dienoyl-[acp] subunit beta: sucC α-limit dextrin -(1->4)-N-acetyl- lysozyme: L-alanyl-L-glutamate all-trans- L-aspartate 4- [(5- phosphoribosylamino) 3-oxo-cis- - 6-phosphate GTP K-12 core type) AcnA: acnA diphosphate kinase 2-isopropylmaleate [acp] reductase: 2-phospho-D-glycerate chiA superoxide arsenate acetate dGTP arsenate arg membrane-bound alpha- alpha- O-acetyl-ADP- octaprenyl bifunctional shikimate semialdehyde shikimate shikimate (S)-2-aceto-2- tetradecenoyl- ADP-forming bifunctional 2-deoxy-2-amino- colanic acid tRNA 2- multifunctional acyl- 6-phospho-beta- peptidase synthase: ispU AroL: aroL methylideneamino]imidazole-4- 3-hydroxyacyl- enoyl-ACP ECTO60_RS22120 dismutase [Mn]: sodA arginine 1,4-dihydroxy- 1,4-dihydroxy- lytic murein galactosidase: bifunctional amylase: ribose deacetylase: diphosphate aspartate kinase/ kinase kinase kinase asp homoserine O- 3-isopropylmalate hydroxybutanoate [acp] a (3R)-3- succinate--CoA ligase 3-keto-L-gulonate- glycogen glycogen chitinase/ D-gluconate arsenate reductase biosynthesis Kdo(2)-lipid A CoA thioesterase glucosidase: shikimate carboxamide isomerase: hisA L-selenocysteine ACP reductase a chitodextrin cytosol nonspecific thiocytidine(32) 2-naphthoate 2-naphthoate T: pepT melA aconitate hydratase malS ECTO60_RS14845 homoserine AroL: aroL AroL: aroL succinyltransferase: metA hydroxybutanoyl-[acp] subunit beta: sucC phosphopyruvate 6-phosphate phosphorylase:phosphorylase: lysozyme: [+ 2 isozymes] (glutaredoxin): arsC decarboxylase: adiA glycosyltransferase I/protease I/ transglycosylase ECTO60_RS04800 di-trans,octa-cis AroK: aroK dehydratase: ketol-acid dehydratase reductase: fabG FabI: fabI dipeptidase: pepD phosphotransferase: synthetase polyprenyltransferase: polyprenyltransferase: 2/2-methylisocitrate kinase 4-hydroxy- bifunctional phosphoribulosylformimino- bifunctional aspartate biosynthesis I (bacteria) hydratase: decarboxylase ECTO60_RS01495ECTO60_RS01495 arsenate reductase 8-oxo-dGTP 8-oxo-GTP biosynthetic arginine WcaE: wcaE lysophospholipase EmtA: emtA -undecaprenyl dehydrogenase shikimate shikimate leuC leuD L-proline a (3R,7Z)-3- 3-hydroxyacyl- chiA hydrogen peroxide arsenite lpxT TtcA: ttcA 6-phospho-beta- AroK: aroK tetrahydrodipicolinate aspartate kinase/ AICAR-phosphate kinase/homoserine reductoisomerase: FabZ: fabZ ECTO60_RS05500 citrate degradation menA menA α-D- dehydratase: acnB a (1->4)- I: thrA shikimate 3-phosphate cys hydroxytetradec- UlaD: ulaD (glutaredoxin): arsC 2+ decarboxylase: speA L1: tesA [+ 6 isozymes] diphosphate kinase kinase ilvC biosynthesis I a (5Z)-tetradec-5-enoyl-[acp] ACP dehydratase a 1,2-diacyl-sn-glycerol 3-phosphate succinyl-CoA 2-oxoglutarate maltodextrin maltodextrin acetate benzene Hg 8-oxo-dGTP glucosidase: a proteinogenic raffinose maltohexaose ADP-D-ribose synthase: dapA homoserine dehydrogenase I: thrA O-succinyl-L-homoserine (2R,3S)-3-isopropylmalate sec agmatine α di-trans,octa-cis a dipeptide galactopyranose D-threo-isocitrate α-D-glucan acetate AroK: aroK AroK: aroK selenide ser a tRNA a (2E)-tetradec- 7-enoyl-[acp] 3-keto-L-gulonate- phosphorylase:phosphorylase: N,N'- glu ala arsenite -L-fucosyl-(1->4)-[2/3- lipid A-core 1- an [L-cysteine ECTO60_RS11080 undecaprenyl- bifunctional aspartate shikimate 3-phosphate (R)-2,3-dihydroxy- (from L-glutamate) FabZ: fabZ diphosphatase a 2-thiocytosine 32 amino acid 3-phosphoshikimate 1- dehydrogenase imidazole 2-enoyl-[acp] 3-hydroxy cis ∆ 7 beta-ketoacyl- an acetyl-holo [citrate diacetylchitobiose a chitodextrin catalase/peroxidase glutathione O-acetyl-α-L-fucosyl]-(1- -undecaprenyl diphosphate diphosphate (2S,4S)-4- [+ 2 isozymes] 6-phosphate malP malP MutT: mutT GDP desulfurase]- GlcNAc-1,6- kinase/homoserine carboxyvinyltransferase: I: thrA shikimate 3- shikimate 3- 3-isopropylmalate 3-methylpentanoate selenide, phosphatidate citrate β phosphate in tRNA sn-glycero-3- DMKH DMKH2-13 a lipid II glycerol glu enoyl-ACP -tetradecenoyl- ACP synthase a (2E)-but-2-enoyl-[acp] phosphoenolpyruvate lyase acyl-carrier protein] beta-N- HPI: katG peroxidase: >3)- -D-glucopyranosyl- L-cysteine oleate 2 anhydro-MurNAc- phosphatase: dehydrogenase II: 3-phosphoshikimate 1- hydroxy-2,3,4,5- cystathionine gamma- dehydrogenase: cytidylyltransferase: cdsA Glycolysis decarboxylase 8-oxo-GMP phosphoethanolamine β-D-glucose aroA bifunctional aspartate phosphate phosphate phosphate L-aspartyl-4-phosphate dihydroxy-acid water serine--tRNA [acp] II: fabF acetylhexosaminidase: catalase HPII: katE ECTO60_RS11195 8-oxo-dGMP arsenite diphosphoundecaprenol pentapeptide ybjG ECTO60_RS23710 carboxyvinyltransferase: tetrahydrodipicolinate leuB glutamate 5- reductase UlaD: ulaD salicyl alcohol synthase: metB dehydratase: ilvD dikinase ligase: serS pyruvate hydroxyl radical 0 6-phosphate 5-enolpyruvoyl- kinase/homoserine synthase: 3-phosphoshikimate 1- 3-phosphoshikimate 1- FabI: fabI dehydratase: enoyl-ACP a CDP-diacylglycerol citrate lyase acyl nagZ Hg undecaprenyl- aroA 4-hydroxy- (2S)-2-isopropyl- kinase: proB SelD: selD a (7Z)-3-oxo- glycolysis III (from glucose) 2-oxoglutarate kinase: pyk arsenite shikimate 3-phosphate dehydrogenase II: hisF hisH carboxyvinyltransferase: carboxyvinyltransferase: aspartate-semialdehyde γ-L-glutamyl fabZ reductase glycolysis I (from glucose 6-phosphate) phosphoenolpyruvate L-xylulose 5-phosphate N-acetyl-D- diphosphate L-homoserine tetrahydrodipicolinate hexadec-7-enoyl-[acp] dehydrogenase E1 carrier protein: citD O H O 5-enolpyruvoyl- 3-oxosuccinate (S)-3-methyl-2-oxopentanoate synthase: ppsA beta-N- 2 2 ECTO60_RS23710 aroA aroA dehydrogenase: asd 5-phosphate sec a myristoyl-[acp] FabI: fabI pyruvate kinase I: glucosamine a [2-oxoglutarate- 10 all-trans- a 1-acyl-2- α ε an [amino group carrier phosphatase: chorismate reductase: dapB L-cystathionine selenophosphate an L-seryl-[tRNA ] a (2E,7Z)-tetradeca- component: sucA L-ribulose-5- [+ 2 isozymes] an L-methionyl- an N - N ,N -diacetyl-lysyl- chitin shikimate 3-phosphate D-erythro-1- 5-enolpyruvoyl- 5-enolpyruvoyl- (7Z)-3-oxo- CDP-diacylglycerol-- CDP-diacylglycerol--serine D-glucopyranose D-glucopyranose ECTO60_RS11370 acetylhexosaminidase: a sulfurated glycerophosphoserine 1,4-dihydroxy- GGPP 1,4-dihydroxy- RNA (R)-NADPHX protein]-C-terminal-γ- an acetyl ester aspartate-semialdehyde SAM dehydrogenase Met formyltetrahydrofolate decaprenyl arachidonoyl- D-alanyl-D-alanine ECTO60_RS03315 homoserine synthase: (S)-2,3,4,5- AICAR (imidazol-4- shikimate 3- shikimate 3- branched-chain- glutamate-5- 2,7-dienoyl-[acp] hexadec-7- glycerol-3-phosphate 3- O-phosphatidyltransferase: 6-phosphate 2-oxoglutarate phosphate 3- nagZ [sulfur carrier] [initiator tRNA ] ATP 2-naphthoate chorismate beta-ketoacyl- a butanoyl-[acp] N,N'- N,N',N''- E2 protein] N 6 - ammonium hydrogencarbonate diphosphate 2-naphthoate sn-glycerol bifunctional ADP- (L-glutamyl)-L-glutamate di-trans,octa-cis kinase: thrB aroC tetrahydrodipicolinate dehydrogenase: amino-acid semialdehyde pssA glucokinase: epimerase: a citryl-holo [citrate synthase: L-homoserine yl)-glycerol phosphate phosphate ACP synthase enoyl-ACP enoyl-[acp] phosphatidyltransferase: glucose-6-phosphate dehydrogenase pyruvate α-D- diacetylchitobiose triacetylchitotriose CTP -undecaprenyl ECTO60_RS07520 cystathionine transaminase: ilvE dehydrogenase: L-seryl-tRNA(Sec) ECTO60_RS07195 octanoyl-L-lysine 3-phosphate beta-N- dependent NAD(P)H- acetylglutamate 2,3,4,5- 3-phosphate chorismate chorismate 4-methyl-2-oxopentanoate reductase reductase: fabG beta-ketoacyl- pgsA isomerase: E1 component: ECTO60_RS22200 lyase acyl-carrier protein] maltotriose glycerophosphodiester serine-type phosphate O-phospho- chorismate aroC beta-lyase: metC proA selenium transferase: II: fabF glucopyranose beta-N- methionyl-tRNA 1,4-dihydroxy- 1,4-dihydroxy- ribonuclease PH: acetylhexosaminidase: hydrate dehydratase/ kinase: argB acetyl esterase: tetrahydropyridine- bifunctional synthase: synthase: FabI: fabI ACP synthase D-glucopyranose ECTO60_RS23055 phosphodiesterase: ugpQ L-homoserine L-aspartate 4-semialdehyde beta-ketoacyl- a (3R,7Z)-3-hydroxy- a 3-sn-phosphatidyl-L-serine ECTO60_RS23225 formate C- L-ribulose-5- citrate lyase acyl 1-phosphate maltodextrin acetylhexosaminidase: lipoyl 2-naphthoate D-Ala-D-Ala ECTO60_RS00350 NAD(P)H-hydrate ECTO60_RS18290 gln homoserine O- homoserine bifunctional maltose branched-chain- ile ECTO60_RS00600 formyltransferase: carbamate kinase: arcC 2-naphthoate phosphatidate nagZ an [amino group carrier chorismate 2,6-dicarboxylate N- histidinol- aroC aroC L-glutamate-5- hexadec-7-enoyl-[acp] II: fabF 1-(3-sn-phosphatidyl)- 6-phosphate phosphate 3- carrier protein: citD synthase: glycerophosphodiester carboxypeptidase: epimerase: threonine regulon transcriptional ACP synthase a (7Z)-tetradec- acetyltransferase: glucosidase: nagZ ECTO60_RS02190 [+ 2 isozymes] polyprenyltransferase: polyprenyltransferase: cytidylyltransferase: protein]-C-terminal- bifunctional anthranilate succinyltransferase: succinyltransferase: kinase: thrB phosphatase/ bifunctional aspartate amino-acid semialdehyde beta-ketoacyl- sn-glycerol 3-phosphate glucose-6-phosphate F6P epimerase: lipA phosphodiesterase: glpQ dacC chorismate repressor/cystathionine I: fabB 7-enoyl-[acp] phosphatidylserine pflB [+ 2 isozymes] malZ N-acetyl-D- menA menA cdsA ECTO60_RS22350 γ-(5-phospho-L- synthase: chorismate mutase/ synthase dapD metA imidazoleglycerol- chorismate transaminase: ilvE an L-selenocysteinyl- (3R,7Z)-3- ECTO60_RS00645 N-acetyl-D- kinase/homoserine ACP synthase decarboxylase: psd isomerase: glucosamine [+ 3 isozymes] a nucleoside chitin Tetrapyrrole Biosynthesis thrC anthranilate beta-lyase MalY: malY [tRNA sec ] a 3-oxohexadecanoyl- beta-ketoacyl- hydroxy-hexadec- phosphatidylglycerophosphatase 6-phosphofructokinase: [+ 2 isozymes] alpha-glucosidase: a [2-oxoglutarate an N-formyl- RNA glucosamine (S)-NADPHX glutamyl)-L-glutamate acetate an alcohol prephenate component N-succinyl- cys O-phospho- phosphate dehydrogenase I: thrA I: fabB ECTO60_RS23225 class II fructose- superpathway of glycolysis and the Entner-Doudoroff pathway oxaloacetate alpha-D-glucose diphosphate synthase bifunctional bifunctional [acp] ACP synthase 7-enoyl-[acp] A: pgpA L-ribulose 5-phosphate ECTO60_RS03195 5'-deoxyadenosine an unsulfurated L-methionyl- a tetrahydrofolate sn-glycerol a CDP-1-acyl- dehydrogenase: I: trpE 2-amino-6- L-homoserine dehydratase leu an L-1-phosphatidylethanolamine pfkA phosphate-specific met dehydrogenase carbamoyl phosphate thr O-succinyl-L- chorismate mutase/ chorismate mutase/ bifunctional aspartate bisphosphatase: [sulfur carrier] met ser demethylmenaquinol-4 α ε component ketopimelate II: fabF dehydratase: fabZ [+ 2 isozymes] F6P class II fructose- 6-phosphofructokinase E2 protein] N 6 [initiator tRNA ] 3-phosphate DMKH2-10 2-arachidonoyl- N ,N -diacetyl- siroheme biosynthesis tyrA homoserine HisB: hisB 2-aminoprop-2-enoate (S)-1-pyrroline- 3-ketoacyl-ACP a 3-oxohexanoyl-[acp] glpX D-glucopyranose acetyl-CoA formate phosphoglucomutase: maltose Amino Acid Degradation D-ala I: trpE N-succinyldiaminopimelate threonine prephenate prephenate kinase/homoserine L-homocysteine L-ribulose-5- glycerol lysyl-D-alanine 3-(imidazol-4- L-methionine biosynthesis II (plants) 5-carboxylate reductase: beta-ketoacyl- a (2E,7Z)-hexadeca- an L-1-phosphatidyl-sn-glycerol bisphosphate II: pfkB 6-phosphate propanoyl CoA ECTO60_RS17285 -lipoyl-L-lysine threonine bifunctional anthranilate synthase: dehydrogenase: dehydrogenase: dehydrogenase II: 6-phosphofructokinase: DHAP phosphate 4- superpathway of acetate 4-alpha- aminotransferase: yl)-2-oxopropyl ECTO60_RS22120 ACP synthase 2,7-dienoyl-[acp] 3-ketoacyl-ACP aldolase: fbaAβ-D-fructose 1,6- degradation I uroporphyrinogen-III chorismate thrC tyrA tyrA ECTO60_RS23710 5-methyltetrahydropteroyltriglutamate- pyrroline-5- pfkA phosphate epimerase: araD utilization and formation superpathway of L-arginine ammonia- anthranilate ECTO60_RS01825 cystathionine phosphate a (3R)-3- I: fabB reductase: acetaldehyde glucanotransferase: L-arginine degradation L-cysteine degradation II L-glutamine uroporphyrinogen-III C- mutase/ bifunctional anthranilate methionine carboxylate enoyl-ACP bisphosphate and L-ornithine degradation L-threonine degradation I L-threonine lyase, N-succinyl- gamma- bifunctional bifunctional - homocysteine S- L-homoserine ECTO60_RS22120 cardiolipin cardiolipin synthase: 6-phosphofructokinase dehydrogenase acetyltransferase: pta [+ 2 isozymes] propanoyl-CoA malQ II (AST pathway) L-threonine degradation I a 5-methylaminomethyl- di-trans,octa-cis α-D-Kdo-(2->4) 6 (1S,2R)-1- synthase glutamate histidinol- reductase: hydroxyhexadecanoyl- triose- degradation III (to 1 an N -(1-hydroxy-2- a 1-acyl-sn-glycero- raffinose cis-vaccenyl methyltransferase: hemX biosynthetic: prephenate L,L-2,6- synthase: metB thr L-homoserine methyltransferase: metE synthase: metH a (9Z)-3-oxohexadec- reductase II: pfkB glucose-6- (acetylating): acetate geranyl 2-thiouridine 34 α 2-oxoglutarate N -methyladenine glycerophosphoglycerol fumarate (S)-NADPHX ethylphosphate bifunctional anthranilate phosphate chorismate chorismate 2-iminopropanoate [acp] synthase ClsB: clsB ECTO60_RS14840 phosphate phosphate propionyl-CoA acetate- methylglyoxal) degradation II selenophosphate -undecaprenyl - -D-Kdo-(2->6) oxopropyl)-[protein]-L-lysine ser C-(indol-3- 3-phosphocholine asp acetate uroporphyrinogen-III C- dehydratase: amidotransferase component proC 9-enoyl-[acp] FabI: fabI a (3R)-3- phosphate D-xylulose 5-phosphate D-glucopyranose arg L-lysine degradation I diphosphate inosine ilvA synthase glutamate diaminopimelate transaminase: mutase/ mutase/ methionine 3-hydroxyacyl- β-D-fructose 1,6- ECTO60_RS18860 acetyltransferase: carboxylase: -CoA thr cys gln in tRNA diphosphate -lipid A (E. coli) yl)glycerol bifunctional ADP- acid phosphatase methyltransferase: cobA pheA TrpG/anthranilate homoserine kinase: thrB hydroxyhexanoyl-[acp] isomerase: dehydrogenase: propionate arg amidotransferase component succinyl- prephenate prephenate synthase: metH 2-iminobutanoate/ 3-ketoacyl-ACP bisphosphate ECTO60_RS07625 accC bifunctional thr 3-phosphate dependent NAD(P)H- bifunctional phosphoribosyltransferase hisC homoserine O- pro ACP a (7Z)-hexadec-7-enoyl-[acp] tpiA (S)-methylmalonyl- ligase: acs threonine ammonia- arginine N- thr asparagine synthase DNA oxidative alpha- AphA: precorrin-1 diaminopimelate L-cystathionine 2-iminopropanoate superpathway of L-serine 3-hydroxyacyl- zwf kinase: tdcD glycerophosphodiester protein deglycase multifunctional acyl- L-aspartate threonine TrpG/anthranilate dehydratase: dehydratase: dehydratase reductase: glucokinase: lys lyase, biosynthetic: ilvA succinyltransferase: maltose regulon L-threonine 3- L-threonine 3- B: ECTO60_RS17405 tRNA 2- Kdo(2)-lipid A galactosidase: hydrate dehydratase/ ECTO60_RS23010 acetyl esterase: TrpD: trpD L-histidinol succinyltransferase: metA L-isoleucine and glycine biosynthesis I ACP dehydratase acetaldehyde CoA [+ 3 isozymes] arginine demethylase phosphodiesterase: glpQ YajL: yajL tryptophan CoA thioesterase oxidase: prephenate phosphoribosyltransferase desuccinylase: pheA pheA met deaminase: FabZ: fabZ ECTO60_RS22120 beta-ketoacyl- Ptd Gro class II fructose- D-glyceraldehyde ECTO60_RS07195 transcriptional dehydrogenase: dehydrogenase: [+ 8 isozymes] selenouridine(34) phosphotransferase: ribonucleoside melA NAD(P)H-hydrate ECTO60_RS18290 uroporphyrinogen-III C- ammonia- O-phospho-L-homoserine 2 bifunctional threonine 2 astA AlkB: alkB alkaline N-(5-phosphoribosyl) dapE phosphate ECTO60_RS21930 biosynthesis III a (3R,9Z)-3- FabZ: fabZ glucose-6-phosphate acetyl phosphate decarboxylase: lysine decarboxylase N -succinyl- glycerophosphodiester protein deglycase synthase: I/protease I/ nadB methyltransferase: hemX lyase/L- TrpD: trpD ACP synthase bisphosphate 3-phosphate ethanolamine acetyl phosphate acetyl-CoA ammonia-lyase/L- repressor/ ECTO60_RS00480 ECTO60_RS00480 glu synthase lpxT hydrolase epimerase: phosphatase: phoA -anthranilate cystathionine prephenate prephenate cys 3-phospho-D-glycerate a (2E)-hexadec- hydroxyhexadec- 6-phospho isomerase: adiA LdcC: ldcC L-arginine phosphodiesterase: ugpQ HchA: hchA trpB trpA lysophospholipase L,L- bifunctional O-succinyl-L-homoserine II: fabF aldolase: fbaA utilization ethanol cystathionine L-threonine L-glutamate MnmH: mnmH RihC: rihC ECTO60_RS22350 uroporphyrinogen-III C- serine N-(5-phosphoribosyl) beta-lyase: pyruvate cystathionine gamma- 2-enoyl-[acp] a (2E)-hex-2-enoyl-[acp] type I propionate serine ammonia- L-threonine L1: tesA α-D- ethanol bifunctional bifunctional bifunctional indole-3-glycerol- histidinol- glu D-3-phosphoglycerate 9-enoyl-[acp] D-glucono- ECTO60_RS23225 biosynthetic L-ornithine lysine decarboxylase sucrose cis-vaccenyl ammonia- -anthranilate diaminopimelate dehydrogenase (R)-methylmalonyl- N-succinylarginine beta-lyase dehydrogenase: degradation IX (via α α NADPH acetate methyltransferase: cobA metC synthase: metB 9 a (9Z)-3-oxo- glyceraldehyde- kinase: tdcD lyase TdcB: tdcB dehydrogenase: -D-Kdo-(2->4)- - formaldehyde succinate D-glyceraldehyde 2-iminosuccinate succinate galactopyranose chorismate chorismate mutase/ phosphate synthase TrpC/ bifunctional bifunctional dehydrogenase: enoyl-ACP 3-hydroxy cis ∆ 1,5-lactone arginine CadA: di-trans,octa-cis- alcohol lyase phosphatase/ enoyl-ACP EutG: eutG CoA (2Z)-2-aminobut-2-enoate dihydrolase: astB MalY: malY yiaY yiaY 4-aminobutanoate) a 5-methylaminomethyl- (2E)-3,7- D-Kdo-(2->6)-lipid adenine glycerol sn-glycerol mutase/ prephenate bifunctional indole-3-glycerol- bifunctional chorismate chorismate mutase/ ECTO60_RS04735 -hexadecenoyl- octadec-9-enoyl-[acp] triose- 3-phosphate [+ 3 isozymes] ECTO60_RS22545 2-aminoprop- L-2-amino-3- undecaprenyl phosphate (R)-lactate a [protein]-L-lysine 3-phosphate trp D-ribofuranose precorrin-2 phosphoribosylanthranilate diaminopimelate imidazoleglycerol- cystathionine gamma- L-cysteine biosynthesis VII reductase 6-phosphogluconolactonase: D-glucopyranose decarboxylase: L-2-amino-3- 34 sn-glycero-3- TdcB: tdcB reductase dehydrogenase: alcohol methylmalonyl- cadaverine N 2 -succinyl- 2-selenouridine dimethylocta- A 1-diphosphate 3-phosphate prephenate dehydrogenase: isomerase TrpF: trpCF phosphate synthase TrpC/ epimerase: dapF maltose regulon mutase/ prephenate (from S-sulfo-L-cysteine) L-cystathionine 3-phosphooxypyruvate FabI: fabI [acp] phosphate phosphate 6-phosphate ornithine 2-enoate oxobutanoate a carboxylate hypoxanthine phosphate synthase: metB (2S, 3S)-3- (9Z)-3-oxo- ECTO60_RS16885 speA oxobutanoate glu L-glutamine phosphocholine (2Z)-2-aminobut- phosphoribosylanthranilate prephenate FabI: fabI gap dehydrogenase acetate CoA mutase: acetyltransferase: pta L-ornithine in tRNA 2,6-diene-1-thiol precorrin-2 dehydratase: tyrA 1-(2- transcriptional dehydratase dehydrogenase: methylaspartate dehydratase: octadec-9- isomerase: decarboxylase AdhP: adhP cadaverine glutamate degradation II 2-enoate isomerase TrpF: trpCF meso- dehydratase: tyrA L-serine biosynthesis I 3-phosphoserine tpiA D-glyceraldehyde D-gluconate ECTO60_RS04715 phosphate SpeF: speF succinylornithine/ glycine C- dehydrogenase: cobA pheA carboxyphenylamino) repressor/ HisB: hisB ser a palmitoyl-[acp] fabZ enoyl-[acp] a hexanoyl-[acp] aminotransferase: decarboxylase: 1-(2- diaminopimelate pheA 3-(4- cystathionine aminotransferase: serC DHAP 13-DPG 6-phosphate agmatine acetylornithine acetyltransferase: kbl 3-(4-hydroxyphenyl) -1-deoxy-D-ribulose cystathionine L-cystathionine reductase: fabG 3-phosphate ethanol succinyl-CoA acetyltransferase: ornithine 2-iminobutanoate ECTO60_RS01005 α β α carboxyphenylamino) 3-phospho- beta-lyase: metC a (2E,9Z)-hexadeca- ygjG gln -D-glucopyranosyl- ADP-L-glycero- - -Kdo-(2->4)- crotonobetainyl- a 5'-half-tRNA 2030 2251 a cis-delta21-39- an organic sirohydrochlorin 3-phenyl-2- pyruvate 5-phosphate beta-lyase histidinol 3-phenyl-2- hydroxyphenyl) phosphogluconate ECTO60_RS07625 decarboxylase: transaminase: astC 2-iminopropanoate GDP-β-L-fucose sn-glycero-3- adenine guanosine diaminopimelate serine O- 2,9-dienoyl-[acp] beta-ketoacyl- type I 2 aminoacetone α 2-methylbutanoate L-carnitine glutathionylspermidine an alkylated DNA canavaninosuccinate -1-deoxy-D-ribulose D-glycerate a (3R,9Z)-3-hydroxy- phosphoglycerate N -succinyl- glutamate glutamate diphosphoundecaprenol D-manno-heptose -Kdo-(2->6)- CoA a 3'-half-tRNA molecule with oxo-40-methyl- hydroperoxide oxopropanoate bifunctional indole-3-glycerol- MalY: malY oxopropanoate pyruvate D-3- bifunctional maltose O-phospho-L-serine dehydratase: edd ECTO60_RS04435 5-aminopentanal 2-iminobutanoate/ gly phosphoethanolamine in 23S rRNA in 23S rRNA aromatic amino decarboxylase: lysA acetyltransferase: octadec-9-enoyl-[acp] ACP synthase glyceraldehyde- kinase: decarboxylase: synthase large lipid IV (E. coli) molecule with a 2',3'-cyclic 23S rRNA 23S rRNA C59:1-[acp] thioredoxin- 5-phosphate histidinol aromatic amino methyloxaloacetate enoyl-ACP F6P 2-iminopropanoate L-glutamate 5- 2-iminobutanoate/ A cyclopropane fatty sirohydrochlorin 2-iminobutanoate acid transaminase: phosphate synthase TrpC/ aromatic amino cystathionine cysE phosphoglycerate regulon transcriptional 3-phosphate agmatinase: aromatic amino bifunctional indole-3-glycerol- dehydrogenase: acid transaminase: phosphoserine II: fabF ECTO60_RS04680 semialdehyde 2-iminopropanoate ECTO60_RS12095 subunit: gltB a 5'-OH end phosphate end (adenine(2030)-N(6) (guanosine(2251) dependent thiol ferrochelatase: cobA phosphoribosylanthranilate beta-lyase: metC dehydrogenase: repressor/cystathionine palmitate reductase (3R,9Z)-3- KDGP aminobutyraldehyde deaminase: colanic acid acetate- glycerophosphodiester L-carnitine bifunctional DNA-3- acyl phospholipid acid transaminase: ECTO60_RS23060 lys 2-aminoprop- acid transaminase: beta-ketoacyl- dehydrogenase: 6-phosphofructokinase: speB 4-aminobutanoate glu lipopolysaccharide argininosuccinate )-methyltransferase -2'-O)- peroxidase: 2-iminobutanoate/ phosphate synthase TrpC/ hisD ECTO60_RS23060 phosphatase: FabI: fabI 3-phospho- Fatty Acid and Lipid Degradation ECTO60_RS21930 succinylglutamate- deaminase: biosynthesis synthase: isomerase TrpF: trpCF L-homocysteine 2-enoate ECTO60_RS23060 bifunctional maltose O-acetyl-L-serine ECTO60_RS04735 beta-lyase MalY: malY hydroxy-octadec- gap class II fructose- dehydrogenase: patD heptosyltransferase -CoA phosphodiesterase: ugpQ CoA- glutathionylspermidine methyladenine siroheme ECTO60_RS23060 aspartate/ phosphoribosylanthranilate thiosulfate ECTO60_RS20855 ACP synthase D-glycerate pfkA ECTO60_RS21930 lyase: argH RlmJ: methyltransferase ECTO60_RS06780 2-iminopropanoate aspartate/ regulon transcriptional 3-phosphooxypyruvate long-chain- 9-enoyl-[acp] semialdehyde glycosyltransferase ligase: acs transferase: amidase/synthase: glycosylase ECTO60_RS11445 tyrosine/aromatic (1S,2R)-1-C-(indol-3- histidinal I: fabB fatty acid elongation -- saturated bisphosphatase: methylglyoxal RfaC: rfaC glycerophosphodiester 2'-5' RNA ligase: ECTO60_RS01135 RlmB: rlmB aspartate/ isomerase TrpF: trpCF aspartate/ fatty-acid-- a palmitoleoyl-[acp] bifunctional 5-aminopentanoate 2-oxobutanoate dehydrogenase: WcaI: wcaI 6 a cis-keto-C60- [+ 2 isozymes] deaminase: 5-methyltetrahydropteroyltriglutamate- tyrosine/aromatic repressor/cystathionine dehydratase: fabZ 2,3- glpX 6-phosphofructokinase oleate β-oxidation caiB ECTO60_RS03705 2: alkA ECTO60_RS05995 an N - 2-O- tyrosine/aromatic aminotransferase: yl)glycerol 3-phosphate tyrosine/aromatic 2-oxobutanoate 2-aminoprop-2-enoate ser 13-DPG 2,3-bisphosphoglycerate- fatty acid β-oxidation I (generic) pyruvate L-asparagine phosphodiesterase: glpQ meroacyl-[acp] ECTO60_RS21930 (1S,2R)-1-C-(indol-3- - homocysteine S- methionine histidinol aminotransferase: beta-lyase MalY: malY cysteine glutathione 3-phosphoserine L-homocysteine CoA ligase diphosphoglycerate- 4-hydroxy-2- II: pfkB astD heptosyl- methyladenine 2030 methylguanosine 2251 an alcohol ECTO60_RS15340 a (2E,9Z)-octadeca- a 3-oxooctanoyl-[acp] DHAP 5-aminovalerate 2-ketobutyrate formate- degradation I 2-methylbutanoyl- aminotransferase: aminotransferase: aminotransferase: FadD: fadD independent oxoglutarate 2 L-canavanine fumarate yl)glycerol 3-phosphate methyltransferase: metE synthase: dehydrogenase: ECTO60_RS15340 synthase acetolactate 2,9-dienoyl-[acp] an acetoacetyl-[acp] phosphoglycerate dependent β-D-fructose 1,6- lyase/pyruvate N - L-aspartate α-L-fucosyl-(1->3)- Kdo -lipid IV diphosphate a DNA containing in 23S rRNA in 23S rRNA 2-oxobutanoate ECTO60_RS15340 tryptophan 2-iminopropanoate serine beta-ketoacyl- phosphoglycerate oleate aminotransferase: ADP 2 A CoA AMP an alkylated metH hisD ECTO60_RS15340 B: cysM serC 5-methyltetrahydropteroyltriglutamate- [+ 3 isozymes] phosphoglycerate aldolase/2- bisphosphate class II fructose- a (3Z)-alk-3-enoyl-CoA succinylglutamate β-D-glucopyranosyl- sn-glycerol crotono-betaine L-carnitinyl-CoA glutathione spermidine tryptophan methionine synthase: hydroxymethyltransferase: ACP synthase 3-ketoacyl-ACP kinase: gabT formate-lyase: tdcE degradation I GDP ethanolamine an apurinic/ a ligated tRNA tyr synthase: 2-aminoprop-2-enoate - homocysteine S- enoyl-ACP mutase: gpmM asn nucleobase tyr L-homocysteine reductase: ECTO60_RS04680 mutase: gpmA dehydro-3-deoxy- bisphosphate triose- diphosphoundecaprenol 3-phosphate apyrimidinic site with a 2'-5' linkage acetolactate phe trpB trpA synthase: synthase: 2-iminobutanoate/ phe O-phospho- ilvN ilvI ECTO60_RS06500 palmitoyl-CoA II: fabF reductase long-chain- succinylglutamate L-asparaginase methyltransferase: metE phosphogluconate aldolase: fbaA ∆ 3 2 putrescine propanoyl-CoA synthase: metH 2-iminopropanoate his a reduced L-serine [+ 4 isozymes] 2-iminopropanoate palmitoleate ECTO60_RS22120 phosphate fatty-acid- -cis-∆ -trans- glutarate semialdehyde desuccinylase: astE D-serine degradation ser trpB trpA S-sulfo-L-cysteine FabI: fabI 3-phospho- 2-phospho- aldolase: 2: ansB asp ilvN ilvI deaminase: 5-methyltetrahydropteroyltriglutamate- methionine gly isomerase: enoyl-CoA L-serine degradation ser glutaredoxin phosphoserine (S)-2-aceto-2- a (3R)-3- D-glycerate D-glycerate -CoA phosphate aspartate/ indole indole - homocysteine S- methionine synthase: metH 2-iminobutanoate/ an (11Z)-3-oxooctadec- ECTO60_RS10495 tpiA isomerase: asparaginase: an N-terminal L- [+ 4 isozymes] met ECTO60_RS21930 glycine ligase putrescine RNase III mRNA 3-(N-morpholino) a (1->4)- UTP an [RNA]-3'- phosphatase: hydroxybutanoate an oleoyl-[acp] hydroxyoctanoyl-[acp] a 3-oxoacyl-[acp] 2,3- phosphopyruvate propionyltransferase: glu D-serine tyrosine/aromatic dithioerythritol thiosulfate an acyl-[acyl- a protein with a nucleoside a holo [BryP acyl- a DNA segment methyltransferase: metE synthase: metH 2-iminopropanoate 11-enoyl-[acp] 2,3-bisphosphoglycerate- fadJ ansA cob(II)inamide glutathione processing α-D-glucan alanyl-[S18 protein ribonucleoside- (S)-2-aceto-2- biosynthesis IV 2-iminopropanoate ECTO60_RS20855 ketol-acid hydratase: FadD: aminotransferase: ECTO60_RS07625 ser aminotransferase: ATP propanesulfonate triphosphate pyruvate met deaminase: 3-hydroxyacyl- diphosphoglycerate- D-glyceraldehyde asp carrier protein] a disulfide bond of 30S ribosome] nucleoside triphosphate carrier protein] recombinase: hydroxybutanoate methionine superpathway of L-alanine biosynthesis 3-ketoacyl-ACP independent fadD γ ygjG D-serine ammonia- ECTO60_RS15340 substrate nucleoside ribosomal- 2',3'- ammonia tryptophan tryptophan alanine reductoisomerase: ACP dehydratase dependent ECTO60_RS05500 -glutamyl- glutarate bifunctional pyrophosphohydrolase: malonyl CoA-ACP ECTO60_RS15865 uracil synthase: metH 2-iminobutanoate/ ser ECTO60_RS21930 reductase: phosphoglycerate 3-phosphate a (2E)-2-enoyl-CoA propanoyl phosphate lyase: dsdA oxaloacetate triphosphate protein-alanine N- cyclophosphate ketol-acid assimilation cycle III synthase: synthase: racemization thr ilvC FabZ: fabZ phosphoglycerate phosphoenol [+ 3 isozymes] L-putrescine threonine thiosulfate reductase FMNH2-dependent maltodextrin mazG RNA 2',3'-cyclic transacylase: degradation L-cysteine biosynthesis I 2-iminopropanoate 3-methyl-2- ECTO60_RS22120 mutase: gpmM type I 2-aminoprop-2-enoate phosphate pyrophosphatase acetyltransferase: recombinase reductoisomerase: trpB trpA trpB trpA low-specificity cys (R)-2,3-dihydroxy- pyruvate 3-ketoacyl-ACP mutase: gpmA pyruvate 4-aminobutanal glutarate ammonia-lyase/L- cob(I)yrinic acid cytochrome glutaredoxin ribonuclease III: alkanesulfonate glucosidase: phosphodiesterase: met deaminase: a (3R,11Z)-3- beta- glyceraldehyde- oleoyl-CoA propionate kinase: tdcD YhdE: yhdE nucleoside triphosphate ECTO60_RS14615 RecA: recA ilvC I (reductive) imidazole- L-threonine oxobutanoate a (2E)-oct-2-enoyl-[acp] reductase: a,c-diamide acyltransferase 2: grxB malZ an N-terminal N-acetyl-rimI thpR a malonyl- a DNA segment glu superpathway of L-asparagine biosynthesis L-glutamate ala ECTO60_RS21930 3-methylpentanoate hydroxyoctadec- ketoacyl- 2-phospho- pyruvate acyl-CoA 3-hydroxybutyryl- hydroxylase: csiD serine ammonia- B subunit: ECTO60_RS06415 monooxygenase: pyrophosphatase an [RNA]-3'- ammonium uracil lactate aldolase: ltaE ECTO60_RS22120 3-phosphate enoyl-CoA acetate kinase: L-proline degradation PlsX: plsX nucleoside triphosphate [BryP acyl- in reverse (R)-2,3-dihydroxy- biosynthesis III dihydroxy-acid branched-chain- ACP acyl-CoA acyl-CoA dehydrogenase: CoA a 2,3,4-saturated (3R γ lyase TdcB: tdcB adenosyltransferase: ECTO60_RS11400 [+ 2 isozymes] ssuD alpha-glucosidase: L-alanyl-[S18 protein YhdE: yhdE ribunucleoside- trp ser alanine 11-enoyl-[acp] D-glycerate phosphoenolpyruvate kinase: pyk dehydrogenase: a 2,3,4-saturated 4-( -L- ECTO60_RS07630 trp degradation gly pyruvate amino-acid enoyl-ACP ECTO60_RS19600 hydratase: epimerase: fadB )-3-hydroxyacyl-CoA (S)-2-hydroxyglutarate cobO pyrophosphohydrolase: ECTO60_RS03195 of 30S ribosome] carrier protein] orientation 3-methylpentanoate racemase: alr dehydratase: 3-hydroxyacyl- synthase a (3R)-3- phosphopyruvate synthase: ppsA pyruvate kinase I: gap dehydrogenase: fatty acid synthetase glutamylamino) [+ 3 isozymes] RNase III UMP 2'-phosphate fadJ mazG dihydroxy-acid glutamate-- imidazole-lactate asp 2-oxoglutarate ilvD transaminase: reductase a 2,3,4-saturatedI: fabB ECTO60_RS11270 FdrA: fdrA propanoate 2-aminoprop-2-enoate 2-iminopropanoate a protein with an mRNA fragment alanine ACP hydroxyacyl-[acyl- hydratase: ECTO60_RS11370 acyl-CoA butanal pro 4,5-cis-dihydroxy- GSSG processing 3-(N-morpholino) a nucleoside 5'- ammonia ligase: 5,6-dihydrouracil glutamate synthase serine O- ilvE FabI: fabI fatty acyl-[acp] 1-pyrroline L-2-hydroxyglutarate adenosylcobinamide sulfite acyl-carrier protein an acyl phosphate reduced L- sulfite dehydratase: racemase: alr (S)-3-methyl-2- dehydratase 3-hydroxyacyl-carrier protein] ECTO60_RS05500 13-DPG acyl-CoA [+ 3 isozymes] a 2,3,4-saturateddehydrogenase: a 2,3,4-saturated (3S 1,2-dithiacyclohexane product mRNA propanal monophosphate a (1->4)- ECTO60_RS24060 acetyltransferase: cysE cys dehydrogenase: lhgO trifunctional 2-iminobutanoate/ triphosphate α D-glucopyranose ilvD large subunit: gltB D-ala oxopentanoate FabZ: fabZ ACP pyruvate dehydrogenase: fatty acyl CoAECTO60_RS11270 )-3-hydroxyacyl-CoA cysteine residues -D-glucan asparagine asparagine val an octanoyl-[acp] phosphoenol 3-hydroxyacyl-CoA transcriptional 2-iminopropanoate (S)-3-methyl-2- imidazole-pyruvate NADP-specific branched-chain- pyruvate dehydratase phosphoglycerate ECTO60_RS19600 4-(γ-L- aminobutyraldehyde 2-oxoglutarate synthase B: synthase B: O-acetyl-L-serine a (2E,11Z)-octadeca- pyruvate dehydrogenase: regulator/proline glutamate hydrogen sulfide FabZ: fabZ kinase: deaminase: oxopentanoate gln ECTO60_RS17405 ECTO60_RS17405 amino-acid cysteine 2,11-dienoyl-[acp] (2E,9Z)- glutamylamino) dehydrogenase: patD dehydrogenase/L- 2-iminopropanoate pyruvate fadB ECTO60_RS21930 3-[(3aS,4S,7aS)-7a-methyl- RNase E mRNA β-D-galactosyl-(1->3)-α- 18 746 966 37 dehydrogenase: ECTO60_RS04680 coenzyme A L-alanine a ribonucleoside a guanosine uridine a guanine adenine branched-chain- 3-ureidopropanoate aspartate--ammonia transaminase: valine--pyruvate desulfurase alanine kinase: pyk octadecenoyl-CoA butanoate glutamate gamma- cob(II)alamin a ferrocytochrome stearoyl-CoA 2-oxoglutarate 1-methyl-dAMP a single adenosylcobinamide ECTO60_RS10940 enoyl-ACP L-tryptophan degradation I coenzyme A 1,5-dioxo-octahydro-1H processing L-fucosyl-(1->4)-[2/3-O- in tRNA in 23S rRNA in 16S rRNA in tRNA val L-homocysteine amino-acid glutamate cysteine synthase B: cysM ilvE transaminase: CsdA: csdA transaminase: 3-phospho- enoyl-CoA acetyl-CoA C- semialdehyde 2-iminobutanoate/ pyruvate ATP b triphosphate stranded DNA 1 ligase: asnA reductase pyruvate kinase I: 5 -inden-4-yl]propanoate substrate bifunctional acetyl-α-L-fucosyl]-(1-> tRNA bifunctional tRNA 16S rRNA tRNA(1)(Val) degradation II 2-iminopropanoate transaminase: synthase large asn glu cysteine synthase A: cysK avtA [+ 2 isozymes] ECTO60_RS07240 a trans-2- D-glycerate hydratase: acyltransferase dehydrogenase: homocysteine S- his FabI: fabI a 2,3,4-saturated enoyl-ACP ECTO60_RS11370 adenosylcobinamide 3)-β-D-glucopyranosyl- (guanosine(18)-2'-O) pseudouridine(32) (guanine(966)-N(2)) (adenine(37)-N(6))- ilvE subunit: gltB ile fadJ a 2,3,4-saturated FadA: fadA a 2,3,4-saturated (via pyruvate) ala putA deaminase: DNA oxidative methyltransferase: reductase enoyl-[acyl- 2,3- (S)-1-pyrroline- DNA kinase/ diphosphoundecaprenolcolanic acid -methyltransferase synthase/23S rRNA -methyltransferase: methyltransferase: fatty acyl-[acp] 2,3-bisphosphoglycerate- (S)-3- alanine ECTO60_RS21930 L-threonine degradation IV cob(I)yrinic acid acyl-CoA desaturase: acyl-CoA synthetase demethylase asn a cis-vaccenoyl-[acp] carrier protein] pyruvate diphosphoglycerate- fatty acyl CoA acetyl-CoA C- 3-oxoacyl-CoA trp 5-carboxylate ribonuclease E: primase: adenosylcobinamide- biosynthesis TrmH: trmH pseudouridine(746) rsmD ECTO60_RS06370 mmuM ile glu β-alanine cys ala FabI: fabI independent hydroxy-(9Z)- fatty acid β- racemase: a,c-diamide FdrA: fdrA AlkB: alkB a 2'-O- an N 2 - an N 6 - dependent acyltransferase ECTO60_RS13480 ECTO60_RS14655 dnaG phosphate acetyltransferase pyruvate β 18 synthase RluA: rluA 966 37 phosphoglycerate octadecenoyl-CoA oxidation III tryptophanase: alr adenosyltransferase: [+ 2 isozymes] 2-O-acetyl- -D-galactosyl- methylguanosine 746 methylguanine methyladenine met phosphoglycerate FadI: fadI 4-aminobutanoate guanylyltransferase: WcaB: wcaB a pseudouridine thr val enoyl-ACP mutase: gpmM 3-hydroxyacyl-CoA (unsaturated, tnaA alanine cobO (1->3)-α-L-fucosyl-(1->4)- in tRNA in 16S rRNA in tRNA Macromolecule Modification mutase: gpmA 2-aminoprop- RNase E cobU in 23S rRNA 1 reductase dehydrogenase: odd number) 4-aminobutyrate- racemase: L-histidine 3-[(3aS,4S,7aS)-7a-methyl- formaldehyde succinate ssDNA/pppN(pN) [2/3-O-acetyl-α-L-fucosyl]- a (3Z)-alk-3- 2-enoate L-glutamate-5- a ferricytochrome oleoyl-CoA dAMP an mRNA fragment processing adenosyl-cobinamide 2-phospho- -2-oxoglutarate alr degradation IV 1,5-dioxo-octahydro-1H- hybrid (1->3)-β-D-glucopyranosyl- cis-vaccenate FabI: fabI fadB adenosylcobalamin b n -1 enoyl-CoA∆ 3 2 semialdehyde low-specificity 5 product mRNA phosphate tRNA-uridine 2-thiolation D-glycerate -cis-∆ transaminase: D-ala triphosphate inden-4-yl]propanoyl-CoA diphosphoundecaprenol queuosine 3-oxo-(9Z)- L-threonine and selenation (bacteria) lipoprotein posttranslational modification phosphopyruvate -trans- acetyl-CoA gabT trifunctional his biosynthesis I (de novo) octadecenoyl-CoA aldolase: ltaE superpathway of purine nucleotides de novo biosynthesis II Nucleoside and Nucleotide Biosynthesis hydratase: enoyl-CoA succinate transcriptional superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis superpathway of pyrimidine superpathway of guanosine superpathway of superpathway of pyrimidine deoxyribonucleoside salvage a [prolipoprotein]- acetyl-CoA C- 2-iminopropanoate ECTO60_RS05500 isomerase: 4 3-(all-trans- 2498 32 745 1498 superpathway of (Kdo) -lipid A biosynthesis Cell Structure Biosynthesis cys semialdehyde regulator/proline a 2-acyl-1-lyso- N-acetyl-D-glucosaminyl-N- a [protein]- an O - a 2'- a cytidine a uridine a guanine a 5,6- a uracil ribonucleotides de novo biosynthesis nucleotides de novo biosynthesis I adenosine nucleotides 2 Hormone Biosynthesis preQ L-cysteine acyltransferase an acyl-[acyl- isethionate a peptide with a 20 Escherichia coli serotype O9a O-antigen biosynthesis UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing) peptidoglycan maturation (meso-diaminopimelate containing) 0 phosphoenol fadJ dehydrogenase/L- acetaldehyde acetylmuramoyl-L-alanyl-D-glutamyl- methylthymine DL-allothreonine deoxyribonucleoside nonaprenyl) dihydrouracil PRPP de novo biosynthesis I 2'-deoxycytidine NADPH-dependent 7- FadI: fadI a (2E)-2- NADP-dependent 2-iminobutanoate/ imidazole-pyruvate gly phosphatidylethanolamine carrier protein] L-cysteine [DNA] leader sequence in 23S rRNA in tRNA in 23S rRNA in 16S rRNA D-ribulose cysteine prolipoprotein pyruvate succinate pyruvate glutamate gamma- 6-carboxy-L-lysyl-D-alanine in DNA 5'-triphosphate benzene-1,2-diol 23S rRNA bifunctional tRNA 23S rRNA in tRNA 16S rRNA gln hydrogencarbonate α cyano-7-deazaguanine enoyl-CoA succinate- 2-iminopropanoate bifunctional 3- tRNA gln UDP-N-acetyl-α-D-glucosamine UDP-N-acetyl- -D-glucosamine lipid II (meso ethylene biosynthesis III (microbes) diacylglyceryl acetyl-CoA C- acetaldehyde hydrogencarbonate IMP a (3R)-3- 5-phosphate indole-3-acetate desulfurase pyruvate semialdehyde deaminase: semialdehyde demethylubiquinone 3- (cytidine(2498)-2'-O) pseudouridine(32) (guanine(745)-N(1)) (uracil(1498)-N(3))- amidophosphoribosyltransferase: purF IMP cytidine deaminase: cdd UDP-N-acetylglucosamine-- diaminopimelate containing) reductase QueF: queF transferase: acyltransferase semialdehyde dehydrogenase FMNH2-dependent dihydrouridine(20/ asp hydroxytetradecanoyl- UDP-N-acetylglucosamine CsdA: csdA dehydrogenase dehydrogenase: bifunctional 2- methylated-DNA-- -methyltransferase synthase/23S rRNA -methyltransferase: methyltransferase: UDP-N-acetyl- arabinose-5- biosynthesis preQ phosphoenolpyruvate kinase: pyk dehydrogenase ECTO60_RS21930 serine RNA-directed O-methyltransferase/2- signal 20a) synthase undecaprenyl-phosphate N- peptidoglycan Amine and Polyamine Biosynthesis a siderophore- 1 ECTO60_RS05085 FadA: fadA + (acetylating): muramoyltetrapeptide alkanesulfonate carbamoyl-phosphate α 1-carboxyvinyltransferase: (NAD ): gabD putA acylglycerophosphoethanolamine [protein]-cysteine S- RlmM: rlmM pseudouridine(746) 1 rlmA 3 rsmE [acp] -D-glucosamine phosphate VI (bacteria) [+ 2 isozymes] synthase: ppsA pyruvate kinase I: I: gabD hydroxymethyltransferase: DNA polymerase: octaprenyl-6-hydroxy peptidase a 2-O- an N - DusA: dusA an N - 5-phospho-β-D-ribosylamine gly carbamoyl- IMP dehydrogenase: 2'-deoxyuridine dCMP acetylglucosaminephosphotransferase: wecA glycosyltransferase bound Fe(III) an [L-cysteine a [prolipoprotein]- (7Z)- pyruvate ECTO60_RS18860 acyltransferase/acyl-ACP carboxypeptidase: ldcA monooxygenase: synthase: carB carA α murA tRNA-guanine imidazole-lactate methyltransferase: ECTO60_RS06500 ECTO60_RS13775 phenol methylase: I: lepB 2498 synthase RluA: rluA 745 20 1498 guaB isomerase N-acetyl- -D-glucosaminyldiphospho- S-1,2-diacyl-sn- ECTO60_RS11370 ssuD methylcytidine 32 methylguanine a uracil in tRNA methyluracil phosphate adenylosuccinate (d)CMP kinase: superpathway of guanine and guanosine salvage acyl-ACP--UDP-N- α MrdB: mrdB superpathway of arginine and polyamine biosynthesis trp desulfurase]-S- hexadecenoyl-CoA glu synthetase: ECTO60_RS05040 ECTO60_RS12560 a pseudouridine KdsD: kdsD ditrans,octacis-undecaprenol UDP-N-acetyl- -D- spermidine biosynthesis III cadaverine transglycosylase: tgt succinate acetyl-CoA 2-methoxy- ECTO60_RS07935 in 23S rRNA in 23S rRNA in 16S rRNA synthase: synthase: purA thymidine kinase: ECTO60_RS15430 acetylglucosamine O- [+ 4 isozymes] sulfanyl-L-cysteine glyceryl-L-cysteine acyl-CoA N-acetyl-D-glucosaminyl-N- in tRNA phosphoribosylamine- asp glucosamine-enolpyruvate biosynthesis pyruvate carbamoyl phosphate carB carA ECTO60_RS13440 arabinose-5- a 7-aminomethyl-7- 6-(all-trans- XMP acyltransferase: lpxA a nascent peptidoglycan dehydrogenase: an L-1- acetylmuramoyl-L-alanyl-D- D-ala a [protein]-S- acetaldehyde [DNA] -glycine ligase: purD dCDP UDP-N- glu a siderophore- 34 lipoprotein a thymine in DNA gly nonaprenyl)phenol glycolaldehyde sulfite a leader sequence a peptide thymidine phosphate with (L-alanyl-γ-D-glutamyl- (indol-3- deazaguanosine in tRNA ECTO60_RS11270 acyl-carrier protein phosphatidylethanolamine glutamyl-6-carboxy-L-lysine adenylo-succinate guanosine SAM arg bound Fe(II) signal peptidase: methyl-L-cysteine carbamoyl dUMP nucleoside- UDP-3-O-[(3R)-3- isomerase α-D-mannosyl-(1->3)-N-acetyl- acetylmuramate glu meso-2,6-diaminopimeloyl-D- lys yl)pyruvate tRNA preQ1(34) S- aspartate asp glutamine- amino-acid N- a [TusA sulfur- ECTO60_RS20645 acyl-CoA hydroxymyristoyl]- GutQ: gutQ α-D-glucosaminyl-diphospho- polymyxin resistance dehydrogenase: murB lysine decarboxylase adenosylmethionine GAR phosphate hydrolyzing GMP adenylosuccinate adenine and thymidine kinase: diphosphate kinase: ala alanyl-D-alanine) pentapeptide arginine carrier protein]-S- dehydrogenase: carbamoyltransferase: pyrB thymidylate α aldehydo-D- glutamate acetyltransferase: adenosylmethionine LdcC: ldcC adenosine salvage III ECTO60_RS13440 ECTO60_RS06635 N-acetyl- -D- ditrans,octacis-undecaprenol α UDP-N-acetyl-α-D-muramate ribosyltransferase- α aspartate synthase: guaA lyase: purB synthase: thyA pyrimidine/purine UDP- -D- ECTO60_RS05135 decarboxylase: sulfanyl-L-cysteine an (S-diacyl-sn- ECTO60_RS19600 Carbohydrate Degradation a 1-(1-alkenyl) 2-O-( -D- an [RNA] 1402 phosphoribosylglycinamide glucosamine arabinose 5- racemase: murI serine-type serine-type decarboxylase: speD lysine decarboxylase isomerase QueA: queA a lipoprotein an N-terminal an L-phenylalanyl- an apo [peptidyl- dihydroxyacetone a cytidine a [release factor]- a holo [PedD acyl- aspartate glucuronate adiA glyceryl)-L-cysteinyl- coenzyme A his15 2-oxoglutarate 1-methyl-dATP -sn-glycero-3- mannosyl)- containing Ins(6)P carbamoyltransferase dCTP nucleoside 2+ signal peptide (2E,7Z)- Phe HPr-P a type IV prepilin in 16S rRNA L-glutamine a protein formyltransferase 2: purT UDP-3-O-acyl-N- phosphate UDP-N- aspartate/glutamate D-Ala-D-Ala D-Ala-D-Ala CadA: Fe (indol-3-yl) arginyl-[protein] [tRNA ] carrier protein] carrier protein] carbamoyltransferase: GMP phosphorylase: UDP-glucuronate N-acetyl-L-glutamate dAdoMet 34 [apolipoprotein] phosphocholine D-glycerate cytidine 16S rRNA peptide chain regulatory subunit: pyrI AMP adenine acetylglucosamine racemase: biosynthetic acetaldehyde an epoxyqueuosine in tRNA signal peptide hexadecenoyl-CoA superpathway of glucose and xylose degradation bifunctional glucose- pyrB α-D-mannosyl-(1->3)-α-D-mannosyl- acetylmuramate--L- carboxypeptidase: carboxypeptidase: a mature peptidoglycan with ECTO60_RS22545 Entner-Doudoroff pathway I L-lyxose degradation D-arabinose degradation I 2-deoxy-D-ribose degradation I L-arabinose chitobiose degradation trehalose degradation I (low osmolarity) (cytidine(1402)-2'-O) release factor malonyl CoA-ACP beta-barrel assembly- inosine/ ppnP dehydrogenase: arginine cadaverine a [TusD sulfur- apolipoprotein N- peptidase enoyl-CoA D-galactosamine and N- 1-phosphatase/ FGAR pyrimidine/purine deacetylase: lpxC (1->3)-N-acetyl-α-D-glucosaminyl- alanine ligase: murC ECTO60_RS05020 dacC dacC (L-alanyl-γ-D-glutamyl-meso- degradation I DNA oxidative transacylase: enhancing protease: aspartate dTMP guanosine kinase: arnA epoxyqueuosine acyltransferase: lnt D-glucopyranose acetyl-D-galactosamine leucyl/phenylalanyl- holo-ACP synthase: -methyltransferase: N(5)-glutamine inositol phosphatase: nucleoside xanthine purine-nucleoside UDP-3-O-(3- 2,6-diaminopimeloyl-D-alanyl- acetylglutamate decarboxylase: carrier protein]-S- SppA: sppA hydratase: N,N'-diacetylchitobiose α,α-trehalose dihydroxyacetone demethylase lysoplasmalogenase: mannosylglycerate prepilin peptidase: ribonuclease I: guanylate kinase: adenylate kinase: D-arabinofuranose diphospho-ditrans,octacis-undecaprenol β [+ 4 isozymes] [+ 5 isozymes] reductase QueH: 6-phosphate D-glucopyranose β-L-lyxopyranose degradation D-arabinopyranose 2-deoxy-D-ribose tRNA--protein ECTO60_RS06435 rsmI methyltransferase: ECTO60_RS14615 ECTO60_RS06770 phosphoribosylformylglycinamidine N-carbamoyl-L-aspartate carbamoyltransferase phosphorylase: ppnP ECTO60_RS18285 phosphorylase: hydroxymyristoyl) UDP- -L-threo- UDP-N-acetyl-α-D- D-glt kinase: argB speA sulfanyl-L-cysteine an N-acyl-(S-diacyl- fadJ a 2'-O- a malonyl- ECTO60_RS15030 ECTO60_RS00330 dTMP kinase: phosphoribosyltransferase: 5-phosphate D-alanine) pentapeptide 6-phosphate L-lyxose N-acetyl-D- L-arabinopyranose 6'-phosphate 6-phosphate kinase: dhaL dhaM AlkB: alkB ECTO60_RS01305 hydrolase: mngB ECTO60_RS03825 ECTO60_RS17695 synthase: purL regulatory subunit: pyrI ECTO60_RS18300 deoD -α-D-glucosamine pentapyranos- superoxide ECTO60_RS13270 sn-glyceryl)-L- (S)-3- chitin transferase: [+ 2 isozymes] 1402 prmC muramoyl-L-alanine (indol-3-yl)acetate a peptide glucose-6- L-arabinose methylcytidine 5 [PedD acyl- myo-inositol a peptide purine-nucleoside ECTO60_RS14585 ECTO60_RS19315 a nascent peptidoglycan agmatine isomerase: galactosamine L-fucose deoxyribokinase: ECTO60_RS16295 a [release factor]-N superpathway of 5-aminoimidazole UDP-3-O-(3- 3-deoxy-8- 4-ulose N-acetylglutamyl-phosphate tRNA cysteinyl-[lipoprotein] hydroxy-(7Z)- phosphate glucose-6- disaccharide in 16S rRNA carrier protein] dihydroorotase: pyrC phosphorylase: deoD [+ 2 isozymes] hypoxanthine α α with D,D cross-links (meso- superoxide 6-phosphate isomerase: rbsK isomerase: alpha,alpha- -methyl-L-glutamine FGAM GDP ribonucleotide biosynthesis hydroxymyristoyl) phosphooctulonate -D-mannosyl-(1->3)- -D-mannosyl- UDP-4-amino-4- yggI epoxyqueuosine(34) hexadecenoyl-CoA phosphate rhaA deacetylase: chbG α-D- a 5'-hydroxy- an [RNA]-3'- N-carbamoyl- ADP adenosine UDP-N- diaminopimelate containing) a [TusE sulfur dehydrogenase: fucI araA N-monoacetylchitobiose a holo [peptidyl- formaldehyde succinate sn-glycero-3- dTDP phosphoribosyltransferase: synthase: kdsA (1->3)-α-D-mannosyl-(1->3)-N- polyamine dismutase dehydrogenase: L-xylulose N-acetylglucosamine- 2-deoxy-D-ribose phosphotrehalase: 3',5'-ADP DHAP a fatty aldehyde (R)-glycerate ribonucleotide- cytidine-3'- L-aspartate guanine glucosamine N- deoxy-L-arabinose acetylmuramoyl-L- N-acetyl- reductase QueG: queG 3-hydroxyacyl-CoA zwf L-ribulose 6'-phosphate L-phenylalanyl-L- carrier protein] Hpr dATP phosphocholine mannopyranose a peptide ECTO60_RS20095 α [Mn]: sodA 34 carrier protein]-S 6-phosphate treC Phe phosphoribosylformylglycinamidine (S)-dihydroorotate PRPP acyltransferase: acetyl- -D-glucosaminyl-diphospho- aminotransferase: alanine--D-glutamate gamma-glutamyl- aminopropyltransferase: a uridine in tRNA dehydrogenase: 6-phospho zwf D-ribulose 5-phosphate arginyl-[protein] a tRNA 3'-[RNA] phosphate nucleoside- -sulfanylcysteine 34 L-xylulokinase: ribonucleotide- adenosine KDO-8P ditrans,octacis-undecaprenol speE met [+ 2 isozymes] a queuosine in tRNA deacetylase: nagA 6-phospho-beta- cyclo-ligase: purM dihydroorotase: nucleoside- lpxD arnB ligase: murD muramoyltetrapeptide phosphate fadB D-glucono- 6-phospho ribulokinase: ribonucleotide- diphosphate deaminase: diphosphate kinase: amidophosphoribosyltransferase: purF GMP L,D-transpeptidase L,D-transpeptidase a mature peptidoglycan 5-oxo-L-proline metabolism lyxK L-fuculokinase: glucosidase: pyrC UDP-2-N,3-O-bis[(3R)- UDP-4-amino- reductase: argC 1 hydrogen D-glucono- N-acetylglucosamine- deoxyribose- araB glucokinase: diphosphate kinase: diphosphate reductase: nrdB nrdA ECTO60_RS11650 ECTO60_RS06635 β LdtC: ldtC carboxypeptidase: ldcA LdtC: ldtC S-methyl-5'- N -(3-aminopropyl) methionine- tRNA 2- 3-oxo-(7Z)- 1,5-lactone AIR 5-phospho- - 3-hydroxytetradecanoyl]- 3-deoxy- 4-deoxy-β-L- meso-diaminopimelate UDP-N-acetyl-α-D-muramoyl- with D,D cross-links (meso- peroxide 1,5-lactone L-xylulose 6-phosphate fucK phosphate ECTO60_RS04800 ECTO60_RS06635 N-acetyl-L-glutamate thioadenosine agmatine hexadecenoyl-CoA L-ribulose 5- D-glucopyranose ECTO60_RS07195 an apo-[LYS2 L- a [protein]- a DNA methyl 3-(all-trans a cytidine 1402 a cis-delta19- reductase: nrdB nrdA D-ribosylamine [+ 4 isozymes] [+ 3 isozymes] a mature peptidoglycan oxo-acid thiouridine(34) a [protein] with a [protein] with 6-phosphogluconolactonase: 5-phosphate 6-phospho-beta- D-glucopyranose an N-terminal an L-phenylalanyl- isobutanal pimeloyl-CoA a holo [PedN acyl- L(or D)-O- PRPP (S)-dihydroorotate class 1b dTTP α-D-glucosamine manno- α α α arabinopyranose L-alanyl-D-glutamate a nascent peptidoglycan with diaminopimelate containing) 6-phosphogluconolactonase: deacetylase: nagA D-ribulose aldolase: coenzyme A 2-aminoadipyl- coenzyme A RNA ala -decaprenyl) 37-methoxy-38- Ins(2)P 5-(carboxyamino) orotate inosine -D-Man-(1->3)- -D-Man-(1->3)- -D-Man- with (L-alanyl-γ-D-glutamyl- 5-semialdehyde transaminase: synthase an N-terminal an N-terminal acetyl-CoA C- ECTO60_RS16885 phosphate 6-phosphate L-lysyl-[protein] Phe L-cysteine phosphotriester in 16S rRNA class 1b ribonucleoside- superpathway of pyrimidine octulosonate-8- bifunctional UDP- γ L-ribulose-5- deoC glucosidase: [tRNA ] carrier protein] phosphoserine phosphoribosylamine- UDP-2,3- (1->2)-α-D-Man-(1->2)-α-D-Man-(1->3)-α- D-ala a nascent peptidoglycan (L-alanyl- -D-glutamyl-meso- a nascent peptidoglycan ECTO60_RS16885 D-galactosamine 1-phosphate fucose degradation carrier-protein] benzene-1,2-diol 16S rRNA methyl-C57:1-[acp] bifunctional glucose- imidazole ribonucleoside- 4-amino-4-deoxy- UDP-N- meso-2,6-diaminopimeloyl- succinylornithine/ ybdL MnmA: mnmA L-glutamine L-glutamate acyltransferase D-gluconate L-ribulose-5- ECTO60_RS11080 bifunctional 3- cyclopropane fatty diphosphate -glycine ligase: purD nucleobases salvage diacylglucosamine phosphatase α α with L,D cross links (meso- 2,6-diaminopimelate) tripeptide with (L-alanyl-γ-D-glutamyl- phosphate 3- 6-phosphate (cytosine(1402)-N(4) malonyl CoA-ACP phosphoserine ribonucleotide orotate GTP pyrimidine/purine D-Man-(1->3)- -Man-(1->3)- -D-GlcNAc- D-alanine) tetrapeptide acetylornithine 4-(methylsulfanyl) FadI: fadI 6-phosphate D-gluconate phosphate 4- methylated-DNA-- acetaldehyde demethylubiquinone 3- acyl phospholipid 1-phosphatase/ diphosphate reductase: nrdF nrdE diphosphatase: lpxH KdsC: kdsC L-arabinose D-alanine--D- acetylmuramoyl-L- epimerase: L-fuculose- D-glyceraldehyde N-acetyl-D-glucosamine leucyl/phenylalanyl- holo-ACP synthase: CoA pyrophosphatase: endoribonuclease )-methyltransferase transacylase: phosphatase: synthase: purK phosphoribosyltransferase: uracil diphospho-ditrans,octacis-undecaprenol diaminopimelate containing) meso-2,6-diaminopimeloyl- hydroxyl radical a 2-thiouridine 34 D-galactosamine- β-L-fucopyranose acetaldehyde epimerase: 8-amino-7- O-methyltransferase/2- synthase: inositol phosphatase: PRPP reductase: nrdF nrdE nucleoside GAR formyltransferase/ alanyl-D-glutamate-- β-D-galactosaminyl-(1->3)-N-acetyl- transaminase: astC spermidine -2-oxobutanoate acetyl-CoA C- 6-phosphogluconate 6-phosphate ECTO60_RS22200 3-phosphate 6-phosphate [protein]-cysteine S- dehydrogenase ECTO60_RS14615 ECTO60_RS20855 orotate alanine ligase: ddlA glycine) tetrapeptide phosphate aldolase: tRNA--protein ECTO60_RS06435 ECTO60_RS10685 toxin ChpB: chpB oxononanoate 4 RsmH: rsmH pyrE phosphorylase: ppnP uracil lipid X α-Kdo α hydrogencarbonate in tRNA acyltransferase 6-phosphate araD methyltransferase: (acetylating): octaprenyl-6-hydroxy an N - ECTO60_RS11445 a malonyl[PedN ECTO60_RS15030 N5-CAIR dADP UDP-glucuronic 2, 6-diaminopimelate -D-galactosamine biosynthesis glutathione dehydrogenase, phosphogluconate ECTO60_RS21380 L-fucose transferase: phosphoribosyltransferase: D-alanine--D- a mature peptidoglycan with a [protein] with L-ribulose-5- deaminase/ acetaldehyde [+ 2 isozymes] synthase: bioF 1402 a cis-methoxy- myo-inositol purine-nucleoside phosphoribosylglycinamide phosphoribosylglycinamide acid oxidase ligase: murE N-acetyl-L-ornithine tRNA uridine(34) 5- FadA: fadA [+ 2 isozymes] kojibiose degradation ECTO60_RS12560 ECTO60_RS18860 phenol methylase: methylcytidine acyl-carrier serine orotate γ UDP-N-acetyl-α-D-glucosamine carbamoyl- γ-L-glutamyl decarboxylating: gndA dehydratase: edd phosphate 3- mutarotase: fucU dehydrogenase ECTO60_RS16295 C59-meroacyl-[acp] ECTO60_RS06750 lipid-A- 3-deoxy-manno- [α-D-Man-(1->3)-α-D-Man-(1->3)-α-D-Man- alanine ligase: a mature peptidoglycan (L-alanyl- -D-glutamyl-meso- carboxymethylaminomethyl an N-terminal 5- isomerase: L-fuculose- D-xylulose an [RNA]-3'- a 5'-hydroxy- 6-(all-trans- ECTO60_RS07935 in 16S rRNA protein] 5-(carboxyamino) orotidine 5'-phosphate dGDP nucleoside- phosphorylase: deoD formyltransferase 2: purT formyltransferase: purN ArnA: arnA UDP-N-acetylglucosamine-- phosphate 5-phosphate (5Z)- D-ribulose epimerase: (acetylating): a holo-[LYS2 L- phosphoribosyltransferase: UMP disaccharide octulosonate (1->2)-α-D-Man-(1->2)] -α-D-Man-(1->3)-α- ECTO60_RS20290 α with L,D cross-links (meso- 2,6-diaminopimelate) tripeptide a mature peptidoglycan glutathione-specific γ- oxo-L-proline ECTO60_RS02925 phosphate α 3',5'-ADP 4'-phosphopantetheine ribonucleoside- ribonucleotide- imidazole diphosphate kinase: n UDP-4-deoxy-4- UDP-N-acetyl- -D-muramoyl- acetylornithine synthesis enzyme tetradecenoyl-CoA KDGP -L-fucopyranose 5-phosphate kojibiose 3',5'-ADP 8-amino-7- decaprenyl)-2- pyrE synthase: lpxB cytidylyltransferase: undecaprenyl-phosphate N- synthase: 5-phosphate ECTO60_RS00645 ECTO60_RS18860 L-phenylalanyl- 2-aminoadipyl- a [protein]-S- coenzyme A hypoxanthine FGAR (d)CMP kinase: D-Man-(1->3)-α-D-Man-(1->3)-α-D-GlcNAc- formamido-β-L- L-alanyl-γ-D-glutamyl- diaminopimelate containing) with (L-alanyl-γ-D-glutamyl- deacetylase: argE ethene MnmG: mnmG glutamylcyclotransferase: D-tagatofuranose aldolase: [DNA] isobutanoyl-CoA NADH H + 3'-phosphate 3'-[RNA] methoxy-phenol ribonucleotide nucleoside- ECTO60_RS06635 D-alanyl-D-alanine acyl-CoA kojibiose a tRNA Phe carrier-protein] oxononanoate orotidine-5'-phosphate lipid A kdsB acetylglucosaminephosphotransferase: wecA carB carA ECTO60_RS13560 L-ribulose 5- fucA L-fucose L-lysyl-[protein] methyl-L-cysteine mutase: purE diphosphate kinase: ECTO60_RS15430 diphospho-ditrans,octacis-undecaprenol arabinopyranose meso-2,6-diaminopimelate lipid IV biosynthesis (P. putida) meso-2,6-diaminopimeloyl- N-acetyl-α-D-glucosaminyldiphospho- tRNA uridine-5- 6-phosphate acetyl-CoA phosphorylase: decarboxylase: pyrF orotidine 5'- disaccharide A dehydrogenase: ribulose- bifunctional phosphate isomerase: fucI xanthine adenine and phosphoribosylformylglycinamidine UMP kinase: pyrH 3-deoxy-manno- undecaprenyl- glycine) tetrapeptide L-ornithine bifunctional tagatose-6- ycjT ECTO60_RS06635 dATP (E. coli) ditrans,octacis-undecaprenol carbamoyl phosphate carboxymethylaminomethyl(34) ECTO60_RS19600 phosphate 3- allose-6- β CAIR UMP phosphate phosphoribosyltransferase: adenosine salvage V synthase: purL octulosonate UDP-N- a (3R)-3- L-ribulose-5- glycolaldehyde -D-glucopyranose UDP phosphate synthesis GTPase MnmE: mnmE 5-oxo-L-proline 4-hydroxy-2- phosphate DHAP L-fuculose sucrose degradation IV (sucrose phosphorylase) acyl-CoA epimerase: phosphate 1-phosphate an osmoregulated a 3-(all-trans 527 ECTO60_RS19315 tetraacyldisaccharide cytidylyltransferase: α α α 4-deoxy-4- acetylmuramoyl- hydroxydecanoyl- UDP-N-acetyl- D-xylose oxoglutarate phosphate 4- kinase: pfkA an L-1-phosphatidyl- an apo-[aryl- N-(4-oxoglutaryl)- an [RNA] a myo-inositol a [phospholipid]- a guanine a [protein]-L- (d)CMP kinase: orotidine-5'- dGTP -D-Man-(1->2)- -D-Man-(1->2)-[ -D-Man- a 5-carboxymethylaminomethyl- rpe isomerase/ periplasmic glucan coenzyme A isobutanoate isovalerate oxalate acetyl-CoA Ins(1)P phosphoribosylaminoimidazolesuccinocarboxamide FGAM nucleoside-diphosphate 4'-kinase: lpxK kdsB tripeptide--D- [acp] α-D-glucosamine ornithine 5-oxoprolinase: dehydrogenase: epimerase: beta- sn-glycerol L-cysteinylglycine -polyprenyl) containing uridine monophosphate palmitoleate in 16S rRNA β-isoaspartate ECTO60_RS15430 phosphate hypoxanthine (1->3)-α-D-Man-(1->3)-α-D-Man-(1->2)- formamido- α 2-thiouridine 34 in tRNA aldolase/2- D-tagatofuranose L-fuculokinase: carrier protein] synthase: purC adenine kinase: ECTO60_RS06635 alanyl-D- alanine N-acetyl- -D-galactosaminyldiphospho- ECTO60_RS11270 xylose ribulose-phosphate ribose-5- araD sucrose phosphoglucomutase: benzene-1,2-diol bifunctional glucose- cyclopropane fatty 16S rRNA bifunctional glucose- protein-L- phosphoribosyltransferase: α-D-Man-(1->2)] -α-D-Man-(1->3)-α-D- L-arabinose carbamoyltransferase: pxpA dehydro-3-deoxy- 1,6-bisphosphate fucK bifunctional 3- UMP kinase: pyrH decarboxylase: phosphoribosylformylglycinamidine lipid IV (E. coli) CMP-Kdo n ditrans,octacis-undecaprenol 5-aminomethyl- isomerase: phosphate acyl phospholipid (guanine(527)-N(7) isoaspartate O- pyrimidine/purine A ligase: murF acyl-ACP--UDP-N- argF pxpC pxpB (2E,5Z)- 3-epimerase: [+ 2 isozymes] pgmB demethylubiquinone 3- 1-phosphatase/ 1-phosphatase/ pyrF ECTO60_RS20095 UTP Man-(1->3)-α-D-Man-(1->3)-α-D-GlcNAc- transferase: Escherichia coli serotype O86 O-antigen biosynthesis phosphogluconate phosphatidylglycerol-- CoA:oxalate deaminated SAICAR UDP nucleoside cyclo-ligase: purM acetylglucosamine O- 2-thiouridine tetradecenoyl-CoA xylA ECTO60_RS01715 isomerase glycolate β holo-ACP synthase: acetate--CoA acetate--CoA ribonuclease I: inositol phosphatase: synthase: )-methyltransferase inositol phosphatase: methyltransferase: diphospho-ditrans,octacis-undecaprenol arnC aldolase: D-xylulose tagatose- L-fuculose 1-phosphate sucrose -D-glucose membrane-oligosaccharide CoA-transferase: glutathione amidase: O-methyltransferase/2- CTP synthase (glutamine UDP-N-acetyl-α-D-muramoyl-L- acyltransferase: lpxA synthase: RpiB: rpiB ECTO60_RS06435 ligase: acs ligase: acs ECTO60_RS17695 ECTO60_RS11445 7 RsmG: rsmG pcm UMP phosphorylase: 3-deoxy-D-manno- 4-deoxy-4- UDP-N-acetyl-α-D-glucosamine protein S-nitrosylation glu D-xylulose ECTO60_RS10495 5-phosphate phosphorylase: 6-phosphate glycerophosphotransferase: ECTO60_RS07285 ECTO60_RS17625 octaprenyl-6-hydroxy ECTO60_RS15030 a [phospholipid]-8- an N - ECTO60_RS15030 a protein L-β- IMP AIR 3 2 bisphosphate adenylosuccinate hydrolyzing): pyrG γ mnmC ∆ ∆ D-xylulose 527 ppnP octulosonic acid α alanyl- -D-glutamyl-meso-2,6- UDP-N-acetylglucosamine-- β-D-galactosyl-(1->3)-N-acetyl- asp L-citrulline and denitrosylation -cis- enoyl-CoA ribose-5- ECTO60_RS12695 [+ 2 isozymes] phenol methylase: myo-inositol (2-hexylcyclopropyl) methylguanine myo-inositol isoaspartate (d)CMP kinase: formamido- -L- aldolase: L-fuculose- opgB lyase: purB ribonucleotide-diphosphate pyrimidine transferase: diaminopimeloyl-D-alanyl-D-alanine UDP-3-O-[(3R)-3- α-D-galactosaminyl-diphospho- a 5-aminomethyl-2- -trans- hydratase: xylulokinase: 5-phosphate α ECTO60_RS15430 purine-nucleoside CTP arabinopyranosyl undecaprenyl-phosphate N- a [protein]- phosphate D-glyceraldehyde kbaY kbaZ a 2-methoxy-ECTO60_RS07935 a 5'-hydroxy- an [RNA]-3'- octanoate in 16S rRNA -methyl ester nucleoside-diphosphate reductase: nrdB nrdA ribonucleosides 3-O-phospho-α-D-Man-(1->2)-α-D-Man- hydroxydecanoyl]- 34 phosphate aldolase: phosphorylase: ECTO60_RS00400 ditrans,octacis acetylglucosaminephosphotransferase: wecA ditrans,octacis-undecaprenol thiouridine in tRNA enoyl-CoA fadJ xylB isomerase pyruvate β α-D-glucopyranose a holo-[aryl- isobutanoyl-CoA diphosphate isovaleryl-CoA diphosphate acetate oxalyl-CoA 2-oxoglutarate L-cysteinylglycine ribonucleotide- uridine-3'- AICAR UMP α α N-acetyl-α-D- α L-cysteine transketolase: 3-phosphate ECTO60_RS21380 -D-fructofuranose an osmoregulated 3',5'-ADP AMP AMP 6-(all-trans- kinase: ECTO60_RS06635 class 1b ribonucleoside- purine deoxyribonucleosides salvage salvage III (1->2)- -D-Man-(1->3)- -D-Man-(1->3) N-acetyl- -D-glucosaminyldiphospho- argininosuccinate 5-methylaminomethyl- isomerase: RpiA: rpiA tagatose- 1-phosphate a 1,2-diacyl-sn-glycerol 3'-[RNA] phosphate kinase: deoD -undecaprenyl D-xylulose ECTO60_RS17845 type I periplasmic glucan with carrier protein] polyprenyl)phenol diphosphate cytidine α-Kdo-(2->6)- -[α-D-Man-(1->2)-α-D-Man-(1->2)-α-D- glucosamine ditrans,octacis-undecaprenol synthase: argG fadB (S)-3- bisphosphate L-fuculose- D-arabinose bifunctional adenosine phosphate 2-thiouridine-forming N-end rule pathway I (prokaryotic) 5-phosphate [+ 4 isozymes] alpha-D-glucose phosphoglycerol substituent pyrH pyrimidine-specific lipid IV (E. coli) Man-(1->3)-α-D-Man-(1->3)] -α-D-Man- 4-deoxy-4-formamido- UDP-3-O-acyl-N- hydroxy-(5Z)- glyceraldehyde- D-galactose degradation I (Leloir pathway) aldolase: phosphate degradation II reductase: nrdF nrdE A n methyltransferase: D-ribose 5- phosphoribosylaminoimidazolecarboxamide guanine and L-arabinose- acetylglucosamine 3-phosphate phosphate-specific gln 2'-deoxyguanosine 2'-deoxyadenosine ribonucleoside (1->3)-α-D-Man-(1->3)-α-D-GlcNAc- a [protein] 3- leucyl/phenylalanyl- (3E,5Z)- tetradecenoyl-CoA gatY gatZ aldolase: fucA fructokinase: formyltransferase/IMP cyclohydrolase: purH UTP UDP guanosine salvage II adenosine KDO transferase: phosphoundecaprenol L-arginino-succinate mnmC phosphate phosphoglucomutase: D-arabinopyranose hydrolase RihA: rihA Kdo transfer to lipid deacetylase: lpxC tetradeca-3,5- 3-hydroxyacyl-CoA D-sedoheptulose D-glyceraldehyde dehydrogenase: β ECTO60_RS18695 UDP-N-acetyl- decaprenyl-diphospho-N- a Chi-site containing an N-formyl-L- 3 1207 2552 deaminase: ECTO60_RS00400 diphospho-ditrans,octacis-undecaprenol N-acetyl-α-D-galactosaminyldiphospho- nitrosothio- tRNA--protein -D-galactopyranose 3-(all-trans-heptaprenyl) an N -methyladenine a UDP-sugar an insertion sequence a guanine uridine an L-glutamyl- nucleoside- deformylase: IV IV (P. putida) UDP-3-O-(3- a 5-methylaminomethyl- gap ECTO60_RS17285 L-fucose α-D-glucosamine acetylmuramoyl-pentapeptide coenzyme A AsbD acyl- double stranded RecA sulfite GSSH Ins(5)P FAICAR dUDP ribonucleoside A L-alanine transferase: dienoyl-CoA dehydrogenase: 7-phosphate 3-phosphate D-glyceraldehyde methionylaminoacyl- benzene-1,2-diol in DNA element IS30 in 16S rRNA in 23S rRNA Gln ECTO60_RS11650 α-Kdo-(2->4)- hydroxydecanoyl) ditrans,octacis-undecaprenol argininosuccinate 34 galactose-1- DHAP DHAP (S)-lactaldehyde isomerase: carrier protein [tRNA ] CTP synthase (glutamine diphosphate kinase: 4-amino-4-ECTO60_RS07815 lipid IV 2-thiouridine in tRNA a [protein] fadJ 3-phosphate D-glucopyranose DNA with a blunt end tRNA bifunctional 3- 16S rRNA 23S rRNA guanosine hydrolase RihC: rihC α A ECTO60_RS16295 acyl-CoA transposase: bifunctional glucose- bifunctional hydrolyzing): pyrG nucleoside-diphosphate ECTO60_RS06635 -Kdo-(2->6)- α CMP-Kdo -α-D-glucosamine lyase: argH an N-terminal epimerase: 6-phosphate fucI bifunctional UDP- glutamyl-tRNA dGMP dAMP cytosine deoxy- -L- (P. putida) tRNA 2- N-terminal L- thioesterase 3-hydroxyacyl-CoA transaldolase: tal 13-DPG undecaprenyldiphospho- demethylubiquinone 3- ECTO60_RS15500 (guanine(1207)-N(2) (uridine(2552)-2'-O) 1-phosphatase/ kinase: ECTO60_RS06635 gln inosine lipid IV (E. coli) 3-O-methylphospho-α-D-Man-(1->2)-α- UDP-3-O-(3- arginyl-[protein] galM D-ribulose DNA-3- thiosulfate sugar hydrolase/ amidotransferase: phosphoribosylaminoimidazolecarboxamide A arabinopyranosyl arg selenouridine(34) leucyl-L-arginine glucose-6-phosphate muramoylpentapeptide beta-N- holo-ACP synthase: O-methyltransferase/2- )-methyltransferase -methyltransferase UTP α α II: tesB dehydrogenase: transaldolase A: exodeoxyribonuclease peptide deformylase: methyladenine sulfurtransferase [+ 9 isozymes] inositol phosphatase: formyltransferase/IMP cyclohydrolase: purH CTP cytosine D-Man-(1->2)- -D-Man-(1->3)- -D-Man- ditrans,octacis α hydroxymyristoyl) N-acetyl-α-D-galactosaminyl-(1->3)-N Aromatic Compound Biosynthesis arg synthase phosphoglycerate [+ 2 isozymes] 5'-nucleotidase: an insertion RsmC: rsmC RlmE: rlmE ECTO60_RS24315 dUTP -D-Kdo-(2->4) 3-deoxy-D-manno- a [protein]- (3E,5Z)- fadB ECTO60_RS06870 isomerase: ribulokinase: acetylglucosaminyltransferase: ECTO60_RS06435 octaprenyl-6-hydroxy glycosylase I: tag GlpE: glpE an N 2 - a 2'-O- ECTO60_RS15030 inosine/ deaminase: codA (1->3)-[α-D-Man-(1->2)-α-D-Man-(1->2) glucosamine N- -acetyl-α-D-galactosaminyldiphospho- MnmH: mnmH S-nitrosoglutathione kinase: V: recC recB recD ECTO60_RS02195 ECTO60_RS18270 an L-glutaminyl- nucleoside guanine -undecaprenyl -α-D-Kdo-(2->6) octulosonic acid leucyl/phenylalanyl- α ECTO60_RS23225 murG [+ 2 isozymes] phenol methylase: sequence IS30 with 1207 2552 CTP L-cysteine tetradecadienoate 3-oxo-(5Z)- -D-galactopyranose araB methylguanine methyluridine myo-inositol Gln dUTP diphosphatase: guanosine kinase: uracil -α-D-Man-(1->3)-α-D-Man-(1->3)] -α-D- acyltransferase: ditrans,octacis-undecaprenol enterobactin biosynthesis arginine a 5-methylaminomethyl- ECTO60_RS04680 [tRNA ] IMP triphosphatase NudI: nudI n phosphate -lipid A (E. coli) transferase: tRNA--protein D-erythrose L-rhamnose ECTO60_RS07935 integrated transposon ECTO60_RS00365 synthase ECTO60_RS18285 Man-(1->3)-α-D-Man-(1->3)-α-D-GlcNAc- lpxD 4-hydroxyphenylpyruvate gallate biosynthesis decarboxylase: S-(hydroxymethyl) tetradecenoyl-CoA F6P D-ribulose in 16S rRNA in 23S rRNA superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) xanthine LpxL/LpxP ECTO60_RS00400 2-(S-geranyl) 4-phosphate 3-phospho- D-allose fructose degradation F6P a double stranded DNA 2-methoxy-6-(all-trans an apurinic site an α-D-aldose UMP CDP (glutamine biosynthesis glutathione transferase: degradation II galactokinase: L-rhamnose degradation I decaprenyl-pyrophosphoryl- a holo-[AsbD acyl- 3-methyladenine glutathione thiosulfate [+ 2 isozymes] family Kdo(2)- diphospho-ditrans,octacis-undecaprenol UDP-2-N-[(3R)-3- adiA thiouridine 34 in tRNA a [protein] acetyl-CoA C- degradation 5-phosphate UDP 3',5'-ADP formate a L-methionylaminoacyl- -heptaprenyl)phenol hydrolyzing) phosphoribosyltransferase: dGDP dADP lipid IV(A) 4- chorismate L-ornithine ECTO60_RS16295 D-glycerate with a RecA protein within DNA 1-phosphate IMP α hydroxydodecanoyl]- dehydrogenase: an N-terminal acyltransferase transketolase: galK (N-acetylglucosamine)-N- carrier protein] tRNA ribonucleotide-diphosphate dUMP CTP ECTO60_RS19315 lauroyl lipid IV(A) lauroyl/ amino-4-deoxy-L- -Kdo-(2->6) β-D-galactosyl-(1->3)-N-acetyl-α- 3-dehydroquinate biosynthetic tRNA 2- N-terminal L- L-rhamnopyranose 2,3- β-D-fructofuranose loaded 3' overhang : pyrG 3-O-[(3R)-3- ECTO60_RS18835 L-lysyl-[protein] ECTO60_RS17845 α-L-rhamnopyranose acetylmuramyl-(pentapeptide) reductase: nrdB nrdA palmitoleoyl arabinosyltransferase: -lipid IV tyr isochorismate type I 3- arginine selenouridine(34) leucyl-L-lysine FadA: fadA α-D-galactose D-allopyranose 1-phosphate trehalose degradation II (cytosolic) nucleoside- acyltransferase: A D-galactosaminyl-(1->3)-N-acetyl- diphosphoglycerate- IMP nucleoside hypoxanthine nucleoside- hydroxydecanoyl]- S-(hydroxysulfenamide) [+ 4 isozymes] UDP-α-D-glucose allose 1-phosphofructokinase: class 1b ribonucleoside- thymidylate synthase: thyA lpxL acyltransferase: arnT (P. putida) α-D-galactosaminyldiphospho- aromatic amino synthase EntC: entC dehydroquinate decarboxylase: synthase acetyl-CoA C- dependent 1-phosphate L-rhamnose dehydrogenase: CTP triphosphatase phosphoribosyltransferase: diphosphate kinase: diphosphate kinase: α-D-glucosamine ornithine kinase: lpxL 3-deoxy-D-manno- acid transaminase: dehydratase: aroD speA MnmH: mnmH glutathione acyltransferase fruK α α a [glycine-cleavage a cytosine 967 a guanine 1835 an oxidized guaB diphosphate NudI: nudI ECTO60_RS20095 ECTO60_RS06635 ECTO60_RS06635 ditrans,octacis-undecaprenol isochorismate decarboxylase D-glyceraldehyde L-rhamnofuranose phosphoglycerate mutarotase: β-D-fructose 1,6- , -trehalose hydrogen cyanide a sulfurated a proteinogenic leukotriene-C4 methanethiol O-succinyl-L- selaginose methyl red a uracil in DNA dTMP 4'-α-L-Ara4N-α- octulosonic acid UDP-2,3- ECTO60_RS23060 3-dehydroshikimate a 5-methylaminomethyl- alsK a sulfurated [sulfur carrier] SAM complex H protein] a 9S rRNA hybrid- Ins(4)P (S)-5-hydroxyisourate reductase: nrdF nrdE kdo(2)-lipid IV(A) synthase MenF: menF SpeF: speF lys FadI: fadI 3-phosphate mutase: gpmA rhaM aldehydo-D-allose bisphosphate [sulfur carrier] amino acid homoserine in 16S rRNA in 23S rRNA α diacylglucosamine agmatine 2-(Se-phospho) N 6 -octanoyl-L-lysine 16S rRNA 23S rRNA CDP palmitoleoyltransferase: Kdo-(2->4)- - transferase: aspartate/ SAM (3Z)-dodec- 6-phosphate cluster protein bifunctional glucose- dTMP kinase: GMP dGTP dATP ornithine 34 type I alpha,alpha-trehalase: dCDP Kdo-(2->6)-[P4'- ECTO60_RS00400 diphosphatase: lpxH isochorismate selenouridine in tRNA 2-phospho- β-L-rhamnopyranose (cytosine(967)-C(5) (guanine(1835)-N(2) NADH hydroxyisourate ECTO60_RS14585 lpxP α β tyrosine/aromatic lysine 3-enoyl-CoA glyceraldehyde- ECTO60_RS13810 kojibiose FMN-dependent uracil-DNA 1-phosphatase/ ribonucleotide- α α-Kdo-(2->4)-α- -L-fucosyl-(1->2)- -D-galactosyl-(1->3) decarboxylase: tRNA 2- D-glycerate bifunctional thiosulfate cystathionine ribonuclease E: )-methyltransferase )-methyltransferase oxidoreductase: hydrolase: hiuH nucleoside-diphosphate ribonucleotide- -L-ara4N]-lipid A aminotransferase: agmatinase: speB adenosylmethionine decarboxylase hydroxylamine ∆ ∆ gamma- phosphorylase: inositol phosphatase: XMP [+ 2 isozymes] diphosphate Kdo-(2->6)-lipid lipid X (P. putida) -N-acetyl-α-D-galactosaminyl-(1->3)-N enterobactin ECTO60_RS04435 selenouridine(34) 3, 2- 3-phosphate L-rhamnono- phosphopyruvate L-rhamnose allose-6- alpha,alpha- lipoyl sulfurtransferase gamma- NADH-azoreductase: glycosylase: ECTO60_RS16360 kinase: ECTO60_RS06635 3-(4- glutamyltransferase: ECTO60_RS14655 RsmB: rsmB 2 RlmG: rlmG (S)-2-oxo-4- diphosphate ECTO60_RS15340 3,5- decarboxylase: speD LdcC: ldcC ycjT 967 an N - ECTO60_RS15030 asp reductase: α-Kdo-(2->4) IV (P. putida) -acetyl-α-D-galactosaminyldiphospho- biosynthesis bifunctional synthase enoyl-CoA dehydrogenase: 1,4-lactone hydratase: isomerase: phosphate trehalase TreF: treF synthase: lipA GlpE: glpE synthase: metB ECTO60_RS12420 ECTO60_RS06345 a 5-methylcytosine dTDP A ECTO60_RS01420 1835 a reduced hybrid- hydroxy-4-carboxy- reductase: lipid-A- hydroxyphenyl) didehydroshikimate gap methylguanine myo-inositol glutamine- dCTP nrdB nrdA -α-Kdo-(2->6) ditrans,octacis-undecaprenol isochorismatase/ lysine decarboxylase MnmH: mnmH isomerase: ECTO60_RS05500 rhaA isomerase/ in 16S rRNA cluster protein 5-ureidoimidazoline nrdB nrdA UDP Kdo - disaccharide pyruvate putrescine dAdoMet tRNA processing β in 23S rRNA hydrolyzing GMP -(lauroyl)-lipid 2 aryl carrier CadA: a 5-methylaminomethyl- fadJ ribose-5- -D-glucopyranose adenylosuccinate nucleoside-diphosphate class 1b synthase: lpxB phosphoenol α-D-glucopyranose β-D-glucopyranose a [glycine-cleavage α,α-trehalose N,N-dimethyl-1,4- an apyrimidinic uracil a 5S rRNA an rRNA fragment (palmitoleoyl) ECTO60_RS22545 2-selenouridine 34 13-DPG keto-L-rhamnulose thiocyanate an unsulfurated α γ succinate 1-phosphate anthranilate synthase: guaA kinase: ECTO60_RS06635 formate ribonucleotide- IV (E. coli) protein EntB: entB ammonium (2E)-dodec- phosphate 5'-deoxyadenosine 6 an unsulfurated an -( -L-glutamyl) met phenylenediamine site in DNA synthase: purA ribonucleoside- ribonucleotide- adenine salvage A -lipid IV lipid A pyruvate glucose and glucose-1-phosphate degradation met complex H protein] N [sulfur carrier] leukotriene-D4 diphosphate lauroyl-Kdo(2) A in tRNA a polycistronic 2-enoyl-CoA L-rhamnonate isomerase [sulfur carrier] -L-amino acid diphosphate disaccharide α-D-galactosyl-(1->3)-[α-L-fucosyl- (2S,3S)-2,3-dihydroxy- cadaverine pyruvate -[(R)-lipoyl]-L-lysine diphosphate lauroyl-Kdo(2) gallate spermidine tRNA precursor phosphoglycerate GMP dTTP reductase: -lipid IV(A) (1->2)]-β-D-galactosyl-(1->3)-N- 2,3-dihydrobenzoate enoyl-CoA RpiB: rpiB adenylo-succinate anaerobic reductase: reductase: -lipid IV(A) (P. putida) synthase: speE kinase: L-rhamnonate kinase: pyk α-D-glucopyranose nrdB nrdA myristoyltransferase: acetyl-α-D-galactosaminyl-(1->3)-N- hydratase: D-allulose 6- adenine and ribonucleoside- nrdF nrdE nrdB nrdA adenine myristoyltransferase: tetraacyldisaccharide 2,3-dihydro-2,3- aminopropylcadaverine ECTO60_RS04680 dehydratase: pyruvate kinase I: 1-phosphate β β msbB L-rhamnulofuranose a [pyruvate dehydrogenase E2 13-[O(2')- -D-glucopyranosyl- -D- a 2,3,4-saturated a pyrimidine a sophorosyloxyfatty an N-acyl-D- adenine 1618 a negatively adenylosuccinate adenosine salvage I class 1b acetyl-α-D-galactosaminyldiphospho- dihydroxybenzoate ser synthase: speE ribonuclease E: fadJ UDP-glucose:α- phosphate D-glucopyranose a proteinogenic glutathione reduced riboflavin melibionate a protein with sn-glycerol guanylate kinase: triphosphate α msbB 4'-kinase: lpxK rhmD ECTO60_RS11370 UDP-glucose 6 glucopyranosyloxy]docosanoate ribonucleotide adenine and dCDP -D-Kdo-(2->4) 5-(methoxycarbonylmethoxy) ECTO60_RS14655 (S)-3- 3-phospho- D-galactose- a sulfurated [sulfur carrier] SAM protein] N -octanoyl-L-lysine 1,2-diacyl-sn- acid 6',6''-diacetate mannosamine in 23S rRNA supercoiled DNA lyase: purB ribonucleoside- ditrans,octacis-undecaprenol dehydrogenase: dhbA ribonuclease E: 2-dehydro- rhamnulokinase: D-allulose-6- amino acid a disulfide bond 3-phosphate ECTO60_RS00330 adenosine salvage II reductase: nrdD -α-D-Kdo-(2->6) (Kdo) -lipid lipid IV uridine biosynthesis hydroxydodecanoyl- D-glycerate 1-phosphate 4-epimerase bifunctional glucose- glucokinase: O(6'')-acetate glycerol 3-phosphate CTP NADPH-dependent N-acetylmannosamine 23S rRNA DNA diphosphate 2 A [EntB aryl-carrier protein] enterobactin non- spermidine aminopropylcadaverine ECTO60_RS14655 pyruvate phosphate 3- L-glyceraldehyde adenine deaminase: adeD adenine -lipid A (E. coli) A, cold adapted (P. putida) [EntF L-seryl-carrier protein] 3-deoxy-L- uridylyltransferase: GalE: galE rhaB 1-phosphatase/ alpha-D-glucose nucleotide 5'- FMN reductase: ssuE kinase: (adenine(1618)-N(6) protein-disulfide topoisomerase adenosine xanthine and nucleoside- reductase: 2,3-dihydroxybenzoate ribosomal peptide a tRNA precursor exoribonuclease CoA 2,3-bisphosphoglycerate- ECTO60_RS07195 alpha- 3-phosphate superpathway of pyrimidine ribonucleosides salvage Secondary Metabolite Biosynthesis rhamnonate galT epimerase: inositol phosphatase: phosphate-specific acetyl esterase: )-methyltransferase reductase DsbD: IV subunit B: parE GDP AMP pyrimidine/purine xanthosine salvage diphosphate kinase: phosphoribosyltransferase: synthetase EntF: entF with a 5' extension fatty acid independent α-D-glucopyranose L-rhamnulose gamma- phosphatidate monophosphate NADPH-dependent galactosidase: ECTO60_RS04155 reductase: adenosine nrdF nrdE holo-ACP synthase: prephenate SAM II: rnb 2-keto-3-deoxy- UDP-α-D-galactose rpe acetyl esterase: α ECTO60_RS22515 ECTO60_RS18325 (2,3-dihydroxybenzoyl) 1-phosphate ECTO60_RS15030 phosphoglucomutase: D-glucopyranose 6-phosphate ECTO60_RS18290 an N-acyl- -D- 6 RlmF: rlmF [+ 3 isozymes] nucleoside ECTO60_RS06635 UTP ECTO60_RS06435 holo-ACP synthase: and a long 3' trailer a tRNA precursor with oxidation phosphoglycerate 1-phosphate lipoyl synthase: lipA glutamyltransferase: cytidylyltransferase: nucleosidase: ppnN assimilatory sulfite melA an N - a protein with ECTO60_RS03645 ribonucleoside cytidine enterobactin synthase methylerythritol phosphate pathway I L-rhamnonate ECTO60_RS17285 ECTO60_RS18290 mannosamine L-glyceraldehyde adenylate synthase: entE ECTO60_RS06435 glucose-1- ECTO60_RS01420 cdsA reductase flavoprotein 1618 a relaxed DNA phosphorylase: ppnP dUDP hypoxanthine [+ 2 isozymes] subunit EntD: entD autoinducer AI-2 biosynthesis I aerobactin biosynthesis a 5' extension and complex mutase: gpmM F6P methyladenine reduced L- adenylate kinase: xanthosine hydrolase [+ 2 isozymes] aldolase: ribose alpha-D-glucose rhamnulose- phosphatase: yihX 6-phosphate 3-phosphate purine-nucleoside dCTP anaerobic carboxy-S- a short 3' extension subunit 2-phospho- a pyrimidine base D-ribose 5- subunit: cysJ α-D- in 23S rRNA cysteine residues ECTO60_RS18300 RihC: rihC cytidine deaminase: cdd D-glyceraldehyde exoribonuclease ECTO60_RS07870 phosphate-specific glucokinase: a sophorosyloxyfatty D-gluconate pyrimidine/purine nucleoside- ribonucleoside- AMP a holo-[EntB aryl-carrier protein] a holo-[EntF L-seryl-carrier protein] (L-seryl)adenylate pyruvate adenosyl-L- ribonuclease alpha phosphorylation 1-phosphate a [pyruvate dehydrogenase phosphate acetate riboflavin galactopyranose phosphorylase: deoD adenine xanthine (2,3-dihydroxybenzoyl)adenylate 3-phosphate II: rnb D-glycerate D-gulosides conversion ECTO60_RS07195 5'-deoxyadenosine acetate sophorosyloxydocosanoate an α-(γ-L-glutamyl) a CDP-2,3,4-saturated- acid O(6'')-acetate nucleoside dCTP deaminase: diphosphate kinase: triphosphate SAM lys ribonuclease PH: P protein phosphoglucomutase: aldolase: rhaD met 6 an unsulfurated [sulfur carrier] L-cysteinylglycine ribonucleotide- adenine phosphoribosyltransferase: methionine FadJ: fadJ phosphopyruvate (S)-lactaldehyde β D-glucopyranose D-glucopyranose 6-phosphate α E2 protein] N -lipoyl-L-lysine -L-amino acid diacylglycerol ECTO60_RS08740 ECTO60_RS06635 reductase: nrdD uridine CMP L-lysine 6- ribonuclease D: ECTO60_RS00350 component: -D-ribopyranose ECTO60_RS17285 to D-glucosides 2-O- -mannosyl-D- diphosphate ADP phosphorylase: ppnP ECTO60_RS19315 dipicolinate biosynthesis synthase 3-hydroxyacyl-CoA hydratase: L-sorbose degradation adenine enterobactin non- 1-deoxy-D-xylulose-5- monooxygenase: ECTO60_RS10730ribonuclease D: D-ribose glycerate degradation adenine [+ 2 isozymes] (d)CMP kinase: enterobactin non- CmoA: cmoA rnpA ECTO60_RS05500 D-glucopyranose DHAP (S)-lactaldehyde reductase: xanthine phosphoribosyltransferase: pyrimidine-specific hypoxanthine phosphate synthase: ECTO60_RS10730 dehydrogenase: pyranase: a D-guloside nucleoside- ribonucleotide- dUTP ribosomal peptide ribosomal peptide 6 ECTO60_RS04300 2-O-(6-phospho- 1 nrdB nrdA ribonucleotide- phosphoribosyltransferase: ECTO60_RS15430 phosphoribosyltransferase: SAH N -hydroxy- a tRNA precursor with fadB 6-phosphate D-guloside 3- keto-L-sorbose an N - p-nitrophenyl-α-D- 1516 α ECTO60_RS18325 ribonucleoside ECTO60_RS18570 phosphoenol rbsD α-D-mannosyl) 37 a sophorosyloxyfatty (Z)-3- a guanine a [protein]- - diphosphate kinase: diphosphate ECTO60_RS18325 synthetase EntF: entF synthetase EntF: entF asp a 5- S-adenosyl-S- a short 3' extension a ferrocytochrome palmitoyl-CoA 2-oxoglutarate glutathione DMAPP an adenosine 3-hydroxypropanoate a holo [BryU acyl- L-cysteate class 1b ribonucleotide- diphosphate xanthine dUTP diphosphatase: uridine kinase: CDP ECTO60_RS20095 L-lysine pyruvate β-D-ribofuranose dehydrogenase: 1-phosphate ethyladenine hypoglycin A galactopyranoside acid O(6'')-acetate ureidoacrylate in 16S rRNA L-glutamate ECTO60_RS06635 reductase: hydrolase RihA: rihA bifunctional aspartate hydroxyuridine 34 carboxymethyl- a tRNA precursor 3-oxododecanoyl- (S)-lactate D-glucono-1,5-lactone -D-glycerate L-sorbose 1- b in tRNA dGMP carrier protein] reductase: phosphoribosyltransferase: ECTO60_RS00365 ECTO60_RS08735 enterobactin synthase enterobactin synthase 5'-methylthioadenosine/ ECTO60_RS12675 trehalose degradation 2-O-(6- 5 in DNA bifunctional NADP- peroxyureidoacrylate/ 16S rRNA aspartate/ ribonucleoside- diphosphate AMP 1-deoxy-D-xylulose 6 pyruvate a 3-dehydro- protein-glutamate O- nrdB nrdA uracil ribonucleoside subunit EntD: entD kinase/homoserine N -hydroxylysine N in tRNA L-homocysteine with a 5' extension CoA VI (periplasmic) α phosphate malonyl CoA-ACP reductase: nrdB nrdA AMP ECTO60_RS19315 [+ 2 isozymes] IMP subunit EntD: entD 5-phosphate S-adenosylhomocysteine phospho- - dependent 3-hydroxy ureidoacrylate (guanine(1516)-N(2) methyltransferase tyrosine/aromatic diphosphate hydrolase RihC: rihC -acetyltransferase: ribonuclease PH: ribonuclease D: acetyl-CoA C- kinase: pyk D-guloside reductase: alpha- transacylase: nrdB nrdA phosphoribosyltransferase: dehydrogenase I: thrA nucleosidase: mtnN melibiose degradation mannosyl)- DNA oxidative tRNA (adenosine(37)-N6) acetyl esterase: acid dehydrogenase/ 5'-deoxynucleotidase: amidohydrolase )-methyltransferase aminotransferase: reductase: class 1b dUMP 1-deoxy-D-xylulose- ECTO60_RS04310 ECTO60_RS00350 ECTO60_RS10730 acyltransferase pyruvate kinase I: α α ECTO60_RS04630 gamma- CheR: cheR ECTO60_RS06750 [+ 2 isozymes] tRNA 5- lactose 3-dehydro-D-guloside , -trehalose D-glycerate D-sorbitol acyl-CoA desaturase: demethylase -dimethylallyltransferase galactosidase: melA ECTO60_RS07655 ECTO60_RS14615 a 2,3-dihydroxybenzoyl- ribonuclease: glutamyltransferase: ECTO60_RS18290 3-hydroxypropionate RutB: rutB 2 RsmJ: rsmJ a [protein]-L- ECTO60_RS15340 nrdF nrdE ribonucleoside- XMP UMP 5-phosphate 6 6 FadI: fadI ECTO60_RS11370 D-ribofuranose an N - a malonyl- thymidylate uracil a seryl-[EntF L-seryl-carrier protein] S-ribosyl-L-homocysteine N -acetyl-N - methoxyuridine(34) degradation III 4-epimerase: D-gluconate hydrolase: 6-phosphate ECTO60_RS13480 AlkB: alkB MiaA: miaA (Z)-3- 5 nucleoside-diphosphate L-aspartyl-4-phosphate rnpA ECTO60_RS01420 dehydrogenase 1516 glutamate-O 3-sulfopyruvate diphosphate [EntB aryl-carrier protein] reductoisomerase: D-mannose melibiose methylguanine [BryU acyl- synthase: thyA (d)CMP kinase: hydroxy-L-lysine /uridine 5-oxyacetic acetyl-CoA C- ECTO60_RS12670 mngB YdfG: ydfG aminoacrylate -methyl-ester reductase: kinase: ECTO60_RS06635 ispC pyruvate degradation ribokinase: lactose alpha,alpha-trehalase: sorbitol-6- 2'-deoxyguanosine in 16S rRNA carrier protein] 6 acid(34) synthase acyltransferase a 3-dehydro- (R)-glycerate D-galactopyranose a sophorosyloxyfatty ECTO60_RS15430 aspartate-semialdehyde S-ribosylhomocysteine citrate:N -acetyl- rbsK ECTO60_RS13810 phosphate 6 37 4-nitrophenol nrdF nrdE dTMP enterobactin non- N -dimethylallyladenosine acetate 3-oxopropanoate 6 CmoB: cmoB FadA: fadA D-mannopyranose D-glucoside alpha-galactosidase: melA palmitoleoyl-CoA a ferricytochrome acetaldehyde an adenine in DNA succinate acid UMP kinase: pyrH dehydrogenase: asd MEP lyase: luxS N -hydroxy-L- ribokinase: alpha,alpha- glycerate dehydrogenase: hypoglycin B L-cysteinylglycine in tRNA GTP ATP dTMP kinase: ribosomal peptide D-lactate 6-phosphate β-D- D-glucoside 3- b pyrimidine aspartate-semialdehyde lysine ligase: mannose-6- rbsK trehalase TreF: treF 2-kinase: srlD 5 dGDP dADP UDP synthetase EntF: entF a 5-(carboxymethoxy) an uncharged tRNA decanoyl-CoA dehydrogenase: dehydrogenase: nucleobases salvage II ECTO60_RS14585 AI-2 ECTO60_RS04315 galactopyranose D-galactopyranose D-glucopyranose dehydrogenase: 2-C-methyl-D- 34 phosphate D-ribofuranose garK keto-D-fructose [+ 2 isozymes] nucleoside-diphosphate enterobactin synthase N 1 -citryl-N uridine in tRNA ldhA ECTO60_RS12665 ECTO60_RS07520 erythritol 4-phosphate acyl-CoA isomerase: 6-phosphate 1 α β cytosine subunit EntD: entD 6 6 5 (S)-lactate 5-phosphate galactose-1-epimerase: galM 2-phospho- α undecaprenyl-diphospho-N an N - an -D- a long-linear an N-acetyl- - RNase G anaerobic anaerobic kinase: ECTO60_RS06635 -acetyl-N - tRNA cmo U34 UDP-N-acetyl- -D-glucosamine a lipid II α-D-glucopyranose S-(2-hydroxyacyl) a cytosine in DNA cholate dTDP cytidylyltransferase: dehydrogenase: manA a D-glucoside [+ 2 isozymes] D-glycerate -acetylmuramoyl-L-alanyl-γ- 2-oxoglutarate methyladenine galactoside α-D-glucan D-hexosaminide a [protein] Ser/Thr degradation chenodeoxycholate ribonucleoside- nucleoside- nucleoside- ribonucleoside- cytosine deaminase: codA L-aspartate 4-semialdehyde hydroxy-L-lysine methyltransferase: α β glutathione dAMP UTP gluconeogenesis I Carbohydrate Biosynthesis ispD ECTO60_RS11270 (R)-lactate F6P -D-glucopyranose -D-glucopyranose D-glutamyl-L-lysyl- D-alanine in DNA DNA cytosine substrate mRNA 7-alpha- 7-alpha- triphosphate diphosphate kinase: diphosphate kinase: triphosphate nucleoside- CMP-diacetamido- colanic acid building blocks biosynthesis UDP-N-acetyl-D- dTDP-L-rhamnose biosynthesis dTDP-N-acetylviosamine an N-(2,3-dihydroxybenzoyl)- cmoM serine/threonine ribonuclease E: uracil 4-(cytidine 5'- (2R,4S)-2-methyl-2,4- aerobactin synthase: periplasmic disulfide bond reduction acyl-CoA methyltransferase: hydroxysteroid hydroxysteroid reductase: nrdD ECTO60_RS06635 ECTO60_RS06635 reductase: nrdD diphosphate kinase: glucosamine biosynthesis I undecaprenyldiphospho- serine-type D-Ala-D-Ala alpha- 4-alpha- beta-N- protein kinase: ECTO60_RS14655 CTP synthase (glutamine 8-epilegionaminic biosynthesis seryl-[EntF L-seryl-carrier protein] 4-hydroxy- diphospho)-2-C- dihydroxydihydrofuran-3-one ECTO60_RS04305 a 5-(methoxycarbonylmethoxy) dehydrogenase: DNA oxidative 5'-deoxynucleotidase: ECTO60_RS21425 uracil (S)-malate α 34 hydroxyacylglutathione ECTO60_RS24125 dehydrogenase: dehydrogenase: ECTO60_RS06635 acid biosynthesis D-glucopyranose D-glucopyranose -D-glucopyranose tetrahydrodipicolinate methyl-D-erythritol uridine in tRNA a [DsbD protein] two reduced muramoylpentapeptide beta-N- carboxypeptidase: dacC galactosidase: glucanotransferase: acetylhexosaminidase: ribonuclease G: hydrolyzing): pyrG UDP-N-acetyl- α-D-glucopyranose enterobactin non- a reduced ECTO60_RS19600 demethylase hydrolase: gloB ECTO60_RS07655 [+ 2 isozymes] hdhA hdhA phosphoribosyltransferase: 6-phosphate 1-phosphate synthase: dapA 4-(cytidine 5'- aerobactin cysteine residues acetylglucosaminyltransferase: [+ 3 isozymes] melA malQ nagZ a [protein] (L-serine/L- α α dTTP α 6-phosphate 1-phosphate carrying a AlkB: alkB a 5-methylcytosine ECTO60_RS02430 3 ,12 -dihydroxy-7- ECTO60_RS06750 -D-glucosamine glucose-6-phosphate glucose-1-phosphate ribosomal peptide thioredoxin (2E)-dec-2- murG threonine) phosphate 7-oxolithocholate dGTP dATP glucose-1-phosphate (2S,4S)-4-hydroxy-2,3,4,5- diphospho) disulfide bond in a protein in DNA an mRNA fragment oxo-5β-cholan-24-oate isomerase: thymidylyltransferase: synthetase EntF: entF (2R,4S)-2-methyl-2,3,3,4- enoyl-CoA 2'-deoxyadenosine UMP CTP alpha-D-glucose glucose-6-phosphate thymidylyltransferase: tetrahydrodipicolinate -2-C-methyl- a N-acetylglucosamine--N- α-D- a non a short 1,4- a 2-hydroxy an N-acetyl-β- malate UDP-2-acetamido- ECTO60_RS23225 rfbA enterobactin synthase tetrahydroxytetrahydrofuran enoyl-CoA ditrans,octacis-undecaprenyldiphospho- UDP glutathione an alcohol phosphate-specific isomerase: rfbA D-erythritol salmochelin an adenine in DNA formaldehyde succinate D-ala acetylmuramyl-(tetrapeptide) galactopyranose galactosylated α-D-glucan carboxylate D-hexosamine dehydrogenase: F6P N-acetyl-(N-acetylglucosaminyl)muramoyl- 2,6-dideoxy- phosphoglucomutase: ECTO60_RS23225 glucose-1-phosphate subunit EntD: entD kinase: ispE biosynthesis hydratase: galactose acceptor glucose-1-phosphate anhydromuropeptides recycling I Secondary Metabolite Degradation γ pyrophosphoryl-undecaprenol mdh β-L-arabino- ECTO60_RS17285 thymidylyltransferase 2-phospho-4-(cytidine fadJ superpathway of hexitol degradation (bacteria) superpathway of hexuronide and hexuronate degradation superpathway of D-glucarate L-alanyl- -D-glutamyl-L-lysyl-D-alanine glutamine-- thymidylyltransferase enterobactin malate hex-4-ulose RfbA: rfbA dipicolinate 5'-diphospho)-2-C- enterobactin (S)-3- and D-galactarate degradation F6P fructose-6- α RfbA: rfbA GlcNAc-1,6- dehydrogenase: α-D- dTDP- -D-glucose hydroxydecanoyl- 3 α dTDP-α-D-glucose methyl-D-erythritol anhMurNAc- galactitol a β-D-glucuronoside UDP-N-acetyl-α-D-glucosamine undecaprenyl-diphospho-N-acetylmuramoyl-L- an N - a single- a [lipoyl-carrier -L-fucosyl-(1->3)- a cytidine 34 in a double-stranded phosphate UDP-N-acetyl- CoA coenzyme A maltohexaose coenzyme A 2-succinylbenzoate (R)-lipoate a ribonucleoside maltose ECTO60_RS12135 glucopyranose dTDP-glucose 4,6- 2-C-methyl-D- preQ biosynthesis D-glucarate alanyl-γ-D-glutamyl-L-lysyl- D-alanyl-D-alanine 2-oxoglutarate methylcytosine β-D-glucopyranosyl- met L-ornithine Metabolic Regulator Biosynthesis mannose-6- 0 L-Ala-γ-D-Glu- VibB stranded RNA protein]-L-lysine [elongator tRNA ] oligonucleotide malate transaminase dTDP-glucose 4,6- β-L-fucosamine monoglucosyl- 5'-monophosphate 1-phosphate phosphate dehydratase: rffG erythritol 2,4- (S)-3- predicted beta- in DNA diphosphoundecaprenol maltose O- UDP-4-amino- (isomerizing) dehydratase: rffG biosynthesis DAP-D-Ala undecaprenyldiphospho- colanic acid tRNA(Met) cytidine ribonucleotide dehydrogenase: UTP--glucose- cyclodiphosphate enterobactin hydroxydecanoyl- PEP-driven glucuronidase: oligoribonuclease: arginine N- 4,6-dideoxy- isomerase: : glmS dTDP-glucose 4,6- UDP-N-acetyl- glucarate muramoylpentapeptide beta-N- biosynthesis acetyltransferase: monophosphatase acetyltransferase: ppGpp metabolism ECTO60_RS12135 dTDP-glucose 4,6- CoA transporter DNA oxidative alpha-glucosidase: ECTO60_RS22380 succinyltransferase: glycine betaine N-acetyl-β- 1-phosphate manA dehydratase: rfbB α-D-glucosamine synthase: ispF GTP N-acetylmuramoyl- uidA galactarate dehydratase: holo-ACP synthase: polyribonucleotide o-succinylbenzoate- lipoate--protein acetyltransferase ECTO60_RS06810 NagD: nagD ECTO60_RS18375 D-glucosamine enterobacterial common antigen biosynthesis dehydratase: rfbB acetylglucosaminyltransferase: ECTO60_RS03195 α astA trehalose biosynthesis I biosynthesis I (Gram- oxaloacetate uridylyltransferase dehydrogenase: of galactitol: demethylase nucleotidyltransferase: pnp -CoA ligase: menE ligase LplA: lplA 4 34 6-O-acetyl- -D- L-idosamine GTP L-alanine amidase: ECTO60_RS05465 2 D-mannopyranose 6-phosphate dTDP-4-dehydro-6- 2-C-methyl-D-erythritol- D-glucopyranuronate murG ECTO60_RS06435 [2/3-O-acetyl-α-L-fucosyl]-WcaF: wcaF an N -acetylcytidine a nucleoside 5'- [+ 4 isozymes] N -succinyl- pppGpp negative bacteria) pyruvate GalU: galU dTDP-4-dehydro-6- fadJ gatA gatB AlkB: alkB met glucopyranosyl- 6-phosphate deoxy-α-D-glucopyranose UDP-2-acetamido- 2,4-cyclodiphosphate cyclohydrolase ECTO60_RS16385 (1->3)-β-D-glucopyranosyl- in [elongator tRNA ] monophosphate a ribonucleoside bifunctional GTP D-glucopyranose deoxy-α-D-glucopyranose 7,8- salmochelin S4 protein-disulfide galactarate glucarate (1->4)-D-glucose L-ornithine α UTP--glucose- phosphoglucosamine α-D-glucopyranose 1-phosphate dTDP-4- 2,6-dideoxy- I FolE: folE 3-hydroxyacyl-CoA [+ 4 isozymes] PTS galactitol diphosphokinase/ UDP- -D-glucose 6-phosphate choline phosphoenolpyruvate phosphomannomutase flavodoxin- dehydratase: dehydratase: a single- D-glucopyranose maltopentaose 4-(2'-carboxyphenyl) a [lipoyl-carrier protein]- diphosphoundecaprenol guanosine-5'- 1-phosphate mutase: glmM β-L-arabino- dihydroneopterin reductase DsbD: dehydrogenase: transporter ditrans,octacis-undecaprenyldiphospho-N- UDP a holo-[VibB aryl- a nucleoside guanosine-3',5'-bis choline carboxykinase phosphoenolpyruvate UDP-2,4- dehydrorhamnose gudD 3',5'-ADP 6 triphosphate,3'-diphosphate CpsG: ECTO60_RS08825 α dependent 3'-triphosphate ECTO60_RS22515 β γ garD acetyl-(N-acetyl-β-D-glucosaminyl)muramoyl-L- a cytosine in DNA formaldehyde succinate diphosphate stranded RNA -4-oxobutyryl-CoA N -[(R)-lipoyl]-L-lysine dehydrogenase: uridylyltransferase -D-glucosamine glucose-1-phosphate 3,5-epimerase: rfbC hex-4-ulose a [DsbD protein] fadB N-acetyl- -D- L-alanyl- -D- subunit IIC: carrier protein] pyrophosphate 3'- diphosphatase: gppA (ATP): pckA synthase: ppsA diacetamido- α-D-mannose (E)-4-hydroxy- alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine GalF: galF 1-phosphate thymidylyltransferase: 6-carboxytetrahydropterin an oxidized an intra- 3-oxodecanoyl- glucosamine-1,6- glutamyl-meso-2,6- ECTO60_RS01220 aldehydo-D- pyrophosphohydrolase: spoT betA 2,4,6-trideoxy- dTDP-4-dehydro- dTDP-viosamine 3-methylbut- with reduced L- aldehydo-D-glucuronate 5-dehydro-4- guanosine 3'-diphosphate 1-phosphate rfbA β synthase QueD: queD triglucosyl- thioredoxin protein disulfide anhydro-N-acetyl- diaminopimeloyl- galacturonate yggI betaine aldehyde phosphoenol β-L-idopyranose bifunctional UDP-N- -L-rhamnose cysteine residues CoA galactitol 1- deoxy-D-glucarate GTP pyrophosphokinase: 5'-triphosphate 3'- UDP-α-D-glucose UDP-N-acetyl-α-D-glucosamine 2-enyl- enterobactin β-D-muramate D-alanine glucuronate glucuronate an N-terminal L- pyruvate mannose-1- acetylglucosamine glucose-1-phosphate dTDP-4- UDP-2-acetamido- 6-carboxy-5,6,7,8- acetyl-CoA C- phosphate glucosyl-(heptosyl) - UDP-α-D-glucuronate 5-amino-4- RNase R degradation a pyrimidine nucleoside adenine 1518 / 3-nonaprenyl-4- a uridine 516 a uridine 38- ECTO60_RS05485 diphosphatase: spoT betaine-aldehyde diphosphate isomerase: isomerase: 2-dehydro-3- 3 PRPP [DNA] [DNA] trans-aconitate hydroxypyruvate phosphate diphosphorylase/ thymidylyltransferase GDP-L-colitose β beta-N- muramoyltetrapeptide Kdo -lipid A-phosphate imidazolecarboxyamide 1519 alanyl-[S5 protein phosphopyruvate UDP-N- dehydrorhamnose 2,6-dideoxy- -L- tetrahydropterin acyltransferase deoxyglucarate 2 substrate RNA adenine in 16S rRNA hydroxybenzoate in 16S rRNA 40 in tRNA dehydrogenase: dTDP-N-acetylviosamine synthase: ispG acetylhexosaminidase: galactitol-1- uxaC uxaC of 30S ribosome] UDP- UDP-glucose 6- guanyltransferase: β glucosamine-1- RfbA: rfbA biosynthesis carboxypeptidase: ldcA 16S rRNA 30S ribosomal 4-hydroxy-3- 16S rRNA trans-aconitate 2- tRNA hydroxypyruvate α α hydratase: UDP-2,4- ADP-L-glycero- -D-manno acetylglucosamine reductase: rfbD lyxo-4-hexulose (E)-4-hydroxy-3- 7-carboxy-7- FadI: fadI phosphate 5- D-sorbitol aldolase: garL , -trehalose mannosylglycerate betB glucose 4- dehydrogenase: cpsB nagZ L-alanyl-γ-D- ribosylpyrimidine (adenine(1518)-N(6)/ hypothetical protein: pseudouridine(38- ECTO60_RS05500 -heptose biosynthesis phosphate N- 2-epimerase (non- α 6 37 periplasmic disulfide bond formation D-tagaturonate D-fructuronate protein S5 alanine polyprenylbenzoate pseudouridine(516) methyltransferase: isomerase: 6-phosphate diacetamido- dTDP- -D-glucose GDP-α-D-mannose dTDP-β-L-rhamnose methylbut-2-en- deazaguanine myo-inositol biosynthesis N -L-threonylcarbamoyladenosine acetyl-CoA C- dehydrogenase: 6-phosphate UDP- adenine ECTO60_RS25805 biosynthesis I epimerase ECTO60_RS03935 GDP-α-D- acetyltransferase hydrolyzing): 1,6-anhydro-N- glutamyl-meso- tartronate semialdehyde exodeoxyribonuclease ribonuclease R: nucleosidase: rihB adenine(1519)-N(6))- N-acetyltransferase: decarboxylase: ubiD synthase RsuA: rsuA ECTO60_RS12005 40) synthase ECTO60_RS18120 glycine betaine 2-phospho- 2,4,6-trideoxy-β- di-trans,octa-cis- GDP- 1-yl diphosphate synthase -modified tRNA biosynthesis acyltransferase gatD salmochelin degradation glucuronate:LPS(HepIII) phosphoribosyltransferase: trehalose- α GalE: galE UDP-glucose 6- mannose D-sedoheptulose GlmU: glmU dTDP-glucose 4,6- two reduced a [DsbA protein] a [DsbB protein] acetyl-β-muramate diaminopimelate sorbitol-6- tagaturonate fructuronate I: sbcB ECTO60_RS22290 dimethyltransferase a double stranded (E)-3- TruA: truA GDP- -D- ECTO60_RS24585 undecaprenyl phosphate α UDP-N-acetyl-β- FadA: fadA glycosyltransferase: waaH ECTO60_RS18325 an N-terminal N-acetyl-rimJ a 16S rRNA 38- tartronate GTP ppGpp phosphatase: D-glycerate L-gulopyranose 7-phosphate UDP-N-acetyl- -D-glucosamine mannose 4,6- 4-hydroxy- QueE: queE D-glucopyranose an electron- keto-D-tagatose phosphate 2-hydroxy-3- 2-nonaprenylphenol a pseudouridine α dehydratase: rffG cysteine residues carrying a with reduced L- reductase: reductase: 6 RsmA: rsmA1518 DNA with 5'- 516 (methoxycarbonyl) mannose dehydrogenase: GDP- D-sedoheptulose N-acetyl- -D- α L-pneumosamine 3-methylbut- 6-phosphate anhydro-N- 6-phosphate D-mannitol iron(III)-[diglucosyl- iron(III)-[monoglucosyl- N -dimethyladenine L-alanyl-[S5 protein pseudouridine semialdehyde otsB 2,3-bisphosphoglycerate- UDP-α-D- UDP-N-acetyl- -D-mannosamine dehydratase: 7-carboxy-7- thr transfer quinone dehydrogenase: ECTO60_RS11995 ECTO60_RS21190 oxopropionate a pyrimidine base terminal phosphate pent-2-enedioate 40 in tRNA ECTO60_RS08920 mannose 4,6- 7-phosphate glucosamine dTDP-glucose 4,6- in a protein disulfide bond cysteine residues octanoyl-CoA acetylmuramic 1-phosphate a 2'- D-ribofuranose 6 1519 of 30S ribosome] independent galactose UDP-N-acetylglucosamine-- gmd 2-enyl deazaguanine enterobactin] complex enterobactin] complex glucosyl-(heptosyl) - /N -dimethyladenine GDP-4-dehydro- srlD reductase: glxR 3 UDP a nucleoside 5'- α,α-trehalose 2-O-(α-D- dehydratase: isomerase: lpcA 1-phosphate UDP-N-acetyl-D- dehydratase: rfbB diphosphate L-threonylcarbamoyladenylate acid kinase: AICAR deoxyribonucleoside [DNA] a diribonucleotide in 16S rRNA bifunctional GTP phosphoglycerate 2,4-diacetamido- α D-glycero-D- undecaprenyl-phosphate N- 7-cyano-7- acyl-CoA D-altronate D-mannonate glucosyluronate-Kdo monophosphate UDP- -D- gmd mannosamine dTDP-4-dehydro-6- α-D-rhamnose synthase type 1 TsaC: tsaC anmK mannitol-1- keto-D-fructose 2-hydroxy-3- 2 nucleoside-diphosphate diphosphokinase/ mannosyl)- manno-heptose bifunctional UDP-N- acetylglucosaminephosphotransferase: wecA UDP-N-acetyl- 4-hydroxy- reductase: Ins(3)P -lipid A-phosphate 5'-monophosphate mutase: gpmM 2,4,6-trideoxy-β- glucuronate α deazaguanine dehydrogenase: N-acetyl-D- 6-phosphate oxopropionate kinase: ECTO60_RS06635 guanosine-3',5'-bis 3-phospho- GDP-4-dehydro- 7-phosphate acetylglucosamine dehydrogenase: deoxy- -D-glucopyranose β ispH threonylcarbamoyl- D-tagatofuranose phosphate 5- 3-phospho- L-gulopyranose -L-fucosamine 3-methylbut- synthase ECTO60_RS11270 altronate iron(III)-[monoglucosyl-(2,3- D-glycerate α-D-rhamnose wecC N-acetyl-α-D- dTDP-4-amino-4,6- bifunctional glucose- AMP synthase: muramate 6- 6-phosphate dehydrogenase: reductase: iron(III)-[salmochelin pyrophosphate 3'- bifunctional D-glycero- diphosphorylase/ 2-enyl QueC: queC mannonate dihydroxybenzoylserine) D-glycerate α dideoxygalactose IPP ECTO60_RS12930 acyl-CoA phosphate mtlD dehydratase: ECTO60_RS02990 S2] complex α-Kdo-(2->4)-α-Kdo- an L-1- a pseudouridine 1915 a DNA containing a cytosine 1962 3-decaprenyl-4- a uracil 747 pyrophosphohydrolase: spoT mannosyl-3- GDP-L- beta-D-manno- glucosamine-1- UDP-N-acetyl- -D- glucosaminyldiphospho- 2-GDP-[(2S,3S,6R)- diphosphate 1-phosphatase/ (L-threonylcarbamoyl) tagatose-6- dehydratase: D-glucopyranose maltopentaose succinate formyl-CoA maltoheptaose ] complex [DNA] an adenine in DNA enterobactin an aldehyde phosphoglycerate dehydrogenase: N-acetylmuramic ECTO60_RS21785 3 (2->6)-lipid IV (E. coli) an apurinic/ guanosine-3',5'- phosphoglycerate fucose heptose-7-phosphate phosphate N- mannosaminuronate ditrans,octacis-undecaprenol transaminase: rffA 5-amino-6-methyl-3,6- preQ inositol phosphatase: adenylate phosphate uxuA A phosphatidylethanolamine in 23S rRNA in 23S rRNA hydroxybenzoate in 23S rRNA GTP pyrophosphokinase: reductase: 0 (R)-glycerate apyrimidinic site phosphatase- kinase: 5,7-diacetamido- ECTO60_RS15030 ECTO60_RS19600 acid 6- altronate 23S rRNA 23S rRNA 4-hydroxy-3- DNA adenine enterochelin 23S rRNA aldehyde ferredoxin ECTO60_RS05485 bis(diphosphate) 3'- CMP-N- synthase: kinase/D-glycero- acetyltransferase dTDP-4-amino-4,6- dihydro-2H-pyran-3-ol] ispH tRNA (N6-adenosine(37)-N6)- kinase: pfkA F6P ECTO60_RS04680 lipopolysaccharide N- isopentenyl- phosphate dehydratase: (pseudouridine(1915)- deoxyribonuclease V: (cytosine(1962)-C(5) (uracil(747)-C(5))- diphosphatase: spoT related protein: 3,5,7,9- acetylneuraminate fcl beta-D-manno- GlmU: glmU α inositol-1- (2E)-oct-2- D-tagatofuranose kdo(2)-lipid A 4-alpha- formyl-CoA--oxalate alpha-glucosidase: polyprenylbenzoate methylase: esterase: oxidoreductase: dideoxy- -D-galactose diphosphate threonylcarbamoyltransferase a [DsbA protein] a [DsbB protein] glycerate 2- exodeoxyribonuclease )-methyltransferase methyltransferase ECTO60_RS09670 tetradeoxy-L- acetylmannosaminouronosyltransferase: rffM an intra- an electron- enoyl-CoA etherase: murQ ECTO60_RS03140 iron(III)-[diglucosyl-(2,3- phosphoethanolamine glucanotransferase: N(3))-methyltransferase ECTO60_RS23405 decarboxylase: ubiD ECTO60_RS15530 ECTO60_RS17830 ECTO60_RS11385 biosynthesis GDP-4-dehydro- heptose 1-phosphate UDP-N-acetyl- dTDP-4-amino-4,6- Delta-isomerase: monophosphatase: complex ATPase TsaE: tsaE with reduced L- carrying a N-acetyl-D- 1,6-bisphosphate 6-phosphofructokinase: kinase: garK iron(III)-[salmochelin CoA-transferase: ECTO60_RS03195 2-O-(α-D- 13-DPG class II fructose- dihydroxybenzoylserine) III: xthA 3 RlmH: rlmH RlmI: rlmI 6 N-(2,3- RlmC: rlmC glycero-D-galacto- protein disulfide transfer quinol enoyl-CoA 7''-transferase: eptB malQ an N - a 2'- 1962 an N -methyladenine 747 GDP UDP-II (bacteria)N-acetyl- 6-deoxy-β- adenylyltransferase α-D-glucosamine N-acetyl-β-D-mannosaminuronyl- dideoxy-D-galactose 2-GDP-[(2S,3S,6R) ECTO60_RS04860 suhB [+ 2 isozymes] cysteine residues disulfide bond glucosamine pfkA 4-deoxy-L-threo-hex-4- S1] complex ECTO60_RS07270 a 5-methylcytosine 2-decaprenylphenol a 5-methyluracil a carboxylate mannosyl)- bisphosphatase: ] complex 1915 dihydroxybenzoyl) non-2-ulosonate 6 hydratase: 2 methylpseudouridine deoxyribonucleoside in DNA α-D-glucosamine L-galactose HldE: hldE α -5-imino-6- an N -L- 6-phosphate tagatose- class II fructose- 6-phosphofructokinase enopyranuronate degradation 2-phospho-D-glycerate in 23S rRNA in 23S rRNA D-glycerate type I β (1->4)-N-acetyl- -D- acyltransferase: rffC glycogen biosynthesis I (from ADP-D-Glucose) myo-inositol glpX 5'-monophosphate -L-serine D-glycero- -D- 37 fadJ II: pfkB 7-O-[2-aminoethoxy(hydroxy) a 2'- in 23S rRNA glyceraldehyde- GDP-L- glucosaminyl-diphospho- dTDP-4-acetamido-4,6- methyloxan-3-ol] threonylcarbamoyladenine N-acetylglucosamine- bisphosphate bisphosphate maltose maltotetraose D-glucopyranose maltohexaose α manno-heptose (S)-3- DHAP 4-deoxy-L-threo-hex- a 1,2-diacyl-sn-glycerol phosphoryl]-α-D-Kdo-(2->4) deoxyribonucleoside [DNA] formate succinyl-CoA triose- 3-phosphate N-acetyl- -D- fucose ditrans,octacis-undecaprenol dideoxy-α-D-galactose DMAPP in tRNA 6-phosphate aldolase: aldolase: fbaAβ-D-fructose 1,6- 1,7-bisphosphate hydroxyoctanoyl- fructoselysine 2-dehydro-3- 4-enopyranuronate -α-D-Kdo-(2->6)-lipid IV 5'-monophosphate phosphate dehydrogenase: CMP-5,7- mannosamine synthase: D-glucopyranose 6-phosphate deacetylase: nagA kbaY kbaZ bisphosphate iron(III)-[salmochelin A D-glycero- UDP-α-D- CoA and psicoselysine deoxy-D-gluconate D-galactarate L-idonate isomerase: gap diacetamido- fcl TDP-N-acetylfucosamine:lipid II N- GDP-4-dehydro-3,6- N-acetylglucosamine- tagatose- triose- SX] complex beta-D-manno- galacturonate alpha-D-glucose fatty acid degradation degradation II degradation 3,5,7,9- acetylfucosaminyltransferase: rffT α 6 bisphosphate α-D-Kdo-(2->4)-α-D- a methylated 1939 tpiA D-glyceraldehyde β biosynthesis I dideoxy- -D-mannose 6-phosphate N -(D-psicosyl) phosphate an L-1- (Z)-2- a 4-hydroxy-3- an N-hydroxy- a uracil α GDP- -L-fucose heptose 1,7- phosphate-specific oxidation 5-dehydro-4-deoxy- D-glucopyranose maltohexaose 2-oxoglutarate a β-D glucoside (R)-glycerate maltopentaose 2,3- -D-lyxopyranose spermidine DHAP tetradeoxy-L- deacetylase: nagA -L-lysine aldolase: isomerase: Kdo-(2->6)-lipid A (E. coli) phosphatidylethanolamine nucleobase methylureidoacrylate polyprenylbenzoate in 23S rRNA 3-phosphate N-acetyl-D- bisphosphate 7- (from UDP-D- phosphoglucomutase: complex galactarate L-idonate diaminopropanoate arylamine glycero-D-galacto- UDP-α-D- (enterobacterial common antigen) gatY gatZ tpiA D-glucuronate within DNA glyoxylate/hydroxypyruvate peroxyureidoacrylate/ 23S rRNA D-lyxose/D- mannosamine phosphatase: glucuronate) ECTO60_RS17285 D-glucosamine galactarate 4-hydroxy-3- N-hydroxyarylamine spermidine N1- non-2-ulosonate glucuronate -undecaprenyl diphosphate subunit KDGP 5-dehydro- reductase GhrB: ghrB ureidoacrylate (uracil(1939)-C(5)) mannose family 6-phosphate dehydratase: kdo(2)-lipid A 4-alpha- diaminopropionate polyprenylbenzoate O-acetyltransferase: acetyltransferase: GDP-D- gmhB α-D-glucopyranose alpha beta-glucosidase alpha-glucosidase: sugar isomerase: β lipid III flippase GDP-β-colitose D-glyceraldehyde 4-deoxy-D- garD 5-dehydro- glucanotransferase: DNA oxidative glyoxylate/hydroxypyruvate amidohydrolase ammonia-lyase: dpaL decarboxylase: ubiD nhoA -methyltransferase speG D-glycero- -D- 1-phosphate FadJ: fadJ 5-dehydro-4- phosphoethanolamine BglX: bglX ECTO60_RS03195 perosamine UDP-α-D- phosphoglucosamine 6 3-phosphate glucuronate D-gluconate demethylase reductase GhrA: ghrA RutB: rutB RlmD: rlmD ECTO60_RS00290 1 class II fructose- β manno-heptose WzxE: wzxE N -(D-fructosyl) 7''-transferase: eptB malQ a 2-(all-trans- an N- 1939 N - biosynthesis N-acetyl- - mutase: glmM bifunctional deoxy-D-glucarate (Z)-2- a 5-methyluracil bisphosphate cellulose galacturonate glucose-1-phosphate 3-hydroxyacyl-CoA -L-lysine isomerase: AlkB: alkB hydroxypyruvate pyruvate D-xylulose acetylspermidine GDP-α-D- neuraminate 1-phosphate (enterobacterial common antigen) type I 4-hydroxy-2- methylaminoacrylate polyprenyl)phenol acetoxyarylamine in 23S rRNA aldolase: fbaA biosynthesis adenylyltransferase: dehydrogenase: α-D-glucosamine glyceraldehyde- kduI mannose bifunctional D-glycero- -undecaprenyl diphosphate oxoglutarate 7-O-[2-aminoethoxy(hydroxy) D-glucopyranose a non glucosylated D-glucopyranose maltotetraose GDP- glgC fadB 1-phosphate sulfoquinovose degradation I a 1,2-diacyl-sn-glycerol maltopentaose maltose a nucleobase beta-D-manno- 3-phosphate aldolase/2- 3-deoxy-D-glycero- phosphoryl]-α-D-Kdo-(2->4) formaldehyde succinate D-glucose acceptor mannose 4,6- cellulose 3-oxooctanoyl- D-gluconate within DNA heptose-7-phosphate a (1->4)-α-D-glucan ADP-α-D-glucose bifunctional UDP-N- dehydrogenase: dehydro-3-deoxy- 2,5-hexodiulosonate 2,5- -α-D-Kdo-(2->6)-lipid A dehydratase: CMP-N-acetyl- UDP- CoA N 6 -(6-phospho- 1-(6-sulfo-α-D- β kinase/D-glycero- acetylglucosamine gap phosphogluconate 2-dehydro- dioxopentanoate gluconokinase: β gmd -neuraminate forming glycogen D-fructosyl) quinovosyl)glycerol -D-fructose 1,6- GDP-4-dehydro- PRPP biosynthesis beta-D-manno- acetyl-CoA C- diphosphorylase/ aldolase: 3-deoxy-D- cellulose synthase -L-lysine gntK an L-1- an (S-diacyl-sn- a plant soluble CMP a 23S rRNA a uridine 65 a [phospholipid]- bisphosphate α acyltransferase glucosamine-1- 13-DPG D-glucopyranose glycyl-glycine glutathione maltotriose a glucan (R)-glycerate -D-rhamnose heptose 1-phosphate ECTO60_RS10495 gluconate 5- glyceryl)-L-cysteinyl- 1911/1915/1917 a [histone]-L-lysine 3-mercaptopyruvate isovaleryl-CoA spermidine D-ribose 5- synthase GlgA: glgA D-gluconate phosphatidylethanolamine heteroglycan uridine in tRNA oleate class II fructose- adenylyltransferase FadI: fadI phosphate N- dehydrogenase [apolipoprotein] glyoxylate/hydroxypyruvate phosphate catalytic phosphoglycerate 6-phosphate 23S rRNA 3-mercaptopyruvate tRNA cyclopropane fatty isovaleryl-CoA spermidine N1- bisphosphatase: a (1->4)-α-D-glucan acetyl-CoA C- acetyltransferase KduD: kduD nucleotide 5'- protein lysine ribose-phosphate subunit: HldE: hldE D-glyceraldehyde 6-sulfo-α-D-quinovose 2-oxoglutarate 4-alpha- 4-alpha- reductase GhrA: ghrA pseudouridine(1911/ sulfurtransferase: pseudouridine(65) acyl phospholipid dehydrogenase: acetyltransferase: glpX GlmU: glmU kinase: pyruvate gamma- monophosphate pyrophosphokinase: ADP-D-glycero-β- acyltransferase β 3-phosphate 2-dehydro-3- glyoxylate/hydroxypyruvate 1915/1917) acetyltransferase: pat synthase: bcsA 1,4-alpha-glucan -D-glucose ECTO60_RS04680 apolipoprotein N- glucanotransferase: glutamyltransferase: glucanotransferase: sseA synthase TruC: truC ECTO60_RS22250 speG GDP-α-D- ECTO60_RS13620 FadA: fadA N-acetyl-α-D- nucleosidase: ppnN F6P cellulose D-manno-heptose branching 6-phosphate lys deoxy-D-gluconate acyltransferase: lnt malQ malQ reductase GhrB: ghrB synthase RluD: rluD a [histone]-N 6 - a pseudouridine 65 ECTO60_RS11445 3-methylcrotonyl- N 8 - PRPP 3-phospho- ECTO60_RS01420 a pseudouridine 1911/ a [phospholipid]- perosamine ADP- glucosamine pyruvate enzyme: glgB hexanoyl-CoA D-glycerate hydroxypyruvate acetyl-L-lysine in tRNA CoA acetylspermidine glucose-6-phosphate 1-phosphate 6-sulfo-D-quinovose D-ribofuranose cytosine 1915/1917 in 23S rRNA dihydrosterculate glyceromanno- an N-acyl-(S-diacyl- a plant soluble isomerase: a glycogen bifunctional UDP-N- 2,3- a 2-acyl-1-lyso- maltose γ-L-glutamyl- a glucan D-glucopyranose 5-phosphate heptose 6- acyl-CoA 2,3-bisphosphoglycerate- D-galactonate degradation autoinducer AI- sn-glyceryl)-L- heteroglycan L-cysteinylglycine ECTO60_RS23225 acetylglucosamine diphosphoglycerate- phosphatidylethanolamine glycylglycine epimerase: rfaD dehydrogenase: independent 2 degradation KDGP cysteinyl-[lipoprotein] D-glucopyranose β diphosphorylase/ dependent ADP-L-glycero- - ECTO60_RS11270 D-glucarate phosphoglycerate D-galactonate 6-deoxy-6- 6-phosphate glucosamine-1- phosphoglycerate AI-2 D-manno-heptose acyl-CoA degradation II mutase: gpmM sulfo-D-fructose mutase: gpmA α α-L-fucosyl-(1->4)-[2/3-O-acetyl-α-L- 955/2504/ 13 phosphate N- galactonate bifunctional UDP- -D-galactose D-glucopyranose a maltodextrin uridine 3-heptaprenyl-4- a uridine dehydrogenase: 6-deoxy-6- fucosyl]-(1->3)-β-D-glucopyranosyl- an aryl sulfate a phenol isoprimeverose (R)-glycerate c-di-GMP 4-nitrocatecholsulfate an acyl phosphate putrescine N-ethylmaleimide acetyltransferase 2-phospho- dehydratase: 4-hydroxy-2- 2580 in 23S rRNA hydroxybenzoate in tRNA ECTO60_RS19600 D-glucarate (4S)-4-hydroxy-5- sulfofructose kinase: glyoxylate/hydroxypyruvate GlmU: glmU dgoD diphosphoundecaprenol cyclic-guanylate- 23S rRNA 4-hydroxy-3- tRNA spermidine N1- glucarate D-glycerate phosphooxypentane- oxoglutarate sulfatase: trans-hex-2- ECTO60_RS24045 colanic acid biosynthesis 4-alpha- reductase GhrB: ghrB specific pseudouridine(955/ polyprenylbenzoate pseudouridine(13) acylphosphatase: acetyltransferase: N-ethylmaleimide enoyl-CoA UDP-N-acetyl- dehydratase: phosphopyruvate 2-dehydro-3-deoxy- 2,3-dione aldolase/2- aryl-sulfate alpha- ECTO60_RS12075 reductase: nemA α 6-deoxy-6-sulfo-D- glycosyltransferase glucanotransferase: glyoxylate/hydroxypyruvate phosphodiesterase 2504/2580) decarboxylase: ubiD synthase TruD: truD ECTO60_RS15170 speG -D-glucosamine ECTO60_RS05465 hydratase: D-galactonate dehydro-3-deoxy- sulfotransferase: xylosidase: yicI enoyl-CoA fructose 1-phosphate WcaC: wcaC malQ reductase GhrA: ghrA PdeB: pdeB synthase RluC: rluC 13 UDP-N-acetylglucosamine ECTO60_RS05500 phosphogluconate ECTO60_RS03415 955/ a pseudouridine hydratase: glucarate 2-dehydro-3- [+ 6 isozymes] a pseudouridine 2-heptaprenylphenol 4-nitrocatechol a carboxylate N-acetylputrescine N-ethylsuccinimide 1-carboxyvinyltransferase: aldolase: hydroxypyruvate in tRNA fadJ dehydratase: phosphoenol deoxygalactonokinase: 3-hydroxy-5- 6-deoxy-6- 5'-phosphoguanylyl(3'->5') 2504/2580 in 23S rRNA murA ECTO60_RS10495 β-D-galactosyl-(1->3)-α-L-fucosyl-(1-> α (S)-3- gudD pyruvate ECTO60_RS24255 phosphooxypentane- sulfofructose-1- UDP a maltodextrin maltose D-glucopyranose -D-xylopyranose guanosine UDP-N-acetyl-α- 5-dehydro-4- 4)-[2/3-O-acetyl-α-L-fucosyl]-(1->3)-β-D- an aryl sulfate a phenol hydroxyhexanoyl- pyruvate 2-dehydro-3- 2,4-dione phosphate aldolase: D-glucosamine- deoxy-D-glucarate D-glyceraldehyde glucopyranosyl-diphosphoundecaprenol CoA phosphoenolpyruvate kinase: pyk deoxygalactonokinase: pyruvate ECTO60_RS24035 enolpyruvate 3-phosphate 3-hydroxyhexanoyl- synthase: ppsA pyruvate kinase I: ECTO60_RS00045 CoA UDP-N- 2-dehydro-3-deoxy- 13-sophorosyloxydocosanoate a 1-O-(alk-1-enyl)-sn-glycero- an [amino group carrier protein]-C- a 3,5,7,9,11,13,15- a cytosine 1407 uridine 2457 RNase E degradation a uridine 55 ECTO60_RS11370 3-sulfolactaldehyde DHAP seleno-L- uroporphyrinogen-III an mRNA spermine 2-oxoglutaramate dehydrogenase: acetylmuramate 2,5- D-galactonate DHAP 6',6''-diacetate 3-phosphoethanolamine terminal-γ-(L-ornithyl)-L-glutamate hepta-oxo- in 16S rRNA in 23S rRNA substrate mRNA in tRNA homocysteine uroporphyrinogen-III C- fadJ dehydrogenase: dioxopentanoate pyruvate 6-phosphate succinylornithine/ hexadecanoyl-[PKS-acp] 16S rRNA 23S rRNA tRNA mRNA spermidine N1- murB sulfolactaldehyde 5-methyltetrahydropteroyltriglutamate- methyltransferase: cobA aldo/keto reductase: (cytosine(1407)-C(5) ribonuclease E: 2-oxoglutaramate 3-hydroxyacyl-CoA curcumin L-galactonate acetylornithine pseudouridine(2457) pseudouridine(55) interferase HigB: acetyltransferase: 3-reductase: yihU - homocysteine S- ECTO60_RS19100 )-methyltransferase ECTO60_RS14655 amidase: yafV dehydrogenase: UDP-N-acetyl- 2-dehydro-3-deoxy-6- acetyl esterase: lysoplasmalogenase: transaminase: astC uroporphyrinogen-III C- synthase RluE: rluE synthase TruB: truB ECTO60_RS03180 speG degradation ribitol degradation methyltransferase: metE [+ 2 isozymes] α-D-muramate phosphogalactonate ECTO60_RS18290 ECTO60_RS01305 an [amino group carrier protein]- methyltransferase: hemX RsmF: rsmF 2457 55 fadB 9-hydroxy-3,5,7,11,13,15- 1407 a pseudouridine a pseudouridine degradation aldehydo-L- 3-sulfopropanediol γ a 5-methylcytosine an mRNA fragment an mRNA fragment N 1 -acetylspermine 2-oxoglutarate aldolase: D-arabitol C-terminal- -(L-glutamate 5- precorrin-2 in 23S rRNA in tRNA 3-oxohexanoyl- UDP-N- 2-oxoglutarate curcumin galactonate SeMet hexaoxohexadecanoyl- in 16S rRNA ECTO60_RS24260 degradation β β semialdehyde-2-yl)-L-glutamate CoA acetylmuramate:L- ribitol 13-[O(2')- -D-glucopyranosyl- -D- sn-glycero-3- [PKS-acp] 2-dehydro-3-deoxy-6- Amine and Polyamine Degradation acetate glucopyranosyloxy]docosanoate a fatty aldehyde acetyl-CoA C- alanyl-gamma-D- D-arabinitol phosphoethanolamine D-tagaturonate O(6'')-acetate acyltransferase glutamyl- meso- dihydrocurcumin phosphogalactonate diaminopimelate aldolase: superpathway of N-acetylglucosamine, FadI: fadI D-ribulose allantoin degradation IV (anaerobic) N-acetylglucosamine ethanolamine utilization allantoin degradation L-carnitine degradation III 4-aminobutanoate ECTO60_RS00050 N-acetylmannosamine and N- 6 ligase: mpl degradation II degradation III 3-methyl-2- an N -L- a 2'- 2604 5,6- acetyl-CoA C- D-xylulose to glyoxylate III 5,10-methylene- a 2-acyl-1-lyso- a double long chain a uridine an α-limit dextrin propane- ribulokinase: acetylneuraminate degradation threonylcarbamoyladenine 37 a uridine in tRNA deoxyribonucleoside 2-phosphoglycolate tellurite dihydrothymine acyltransferase UDP-N-acetyl- N-acetyl-D- L-carnitine oxobutanoate tetrahydromethanopterin phosphatidylethanolamine stranded DNA in 23S rRNA 1,3-diamine araB D-glyceraldehyde (S)-(+)-allantoin ethanolamine polyphosphate NAD-dependent α xylulokinase: N-acetylneuraminate 4-aminobutanoate in tRNA tRNA dihydrouridine 5'-monophosphate 23S rRNA 4-alpha- spermidine N1- FadA: fadA -D-muramoyl- tetrahydrocurcumin pyruvate glucosamine (S)-(+)-allantoin phosphoglycolate tellurite resistance D-ribulose 3-phosphate xylB N-acetylneuraminate N-acetylglucosamine 4-aminobutyrate- tRNA cyclic N6- synthase DusB: dusB exodeoxyribonuclease glucanotransferase: dihydropyrimidine L-alanyl-γ-D- ethanolamine allantoinase 3-methyl-2-oxobutanoate exopolyphosphatase: ppx 5'-deoxynucleotidase: pseudouridine(2604) phosphatase: methyltransferase acetyltransferase: butanoyl-CoA 5-phosphate allantoinase threonylcarbamoyladenosine(37) lysophospholipase V: recC recB recD dehydrogenase glutamyl-meso-2,6- D-xylulose lyase: nanA kinase: nagK ammonia-lyase: -2-oxoglutarate hydroxymethyltransferase: tRNA dihydrouridine(16) ECTO60_RS07655 synthase RluF: rluF malQ ECTO60_RS01720 TehB: tehB speG AllB: allB N-acetyl-D- AllB: allB synthase TcdA: tcdA α subunit PreA: preA 5-phosphate N-acetylneuraminate ECTO60_RS06940 transaminase: 6 L2: pldB synthase DusC: dusC 2604 a -limit dextrin diaminopimelate glucosamine allantoate panB a cyclic N -L- long chain a 2'- a pseudouridine N-(3-aminopropyl) acyl-CoA lyase: gabT a 5,6-dihydrouridine in tRNA a 5'-phosphooligonucleotide with short branches glycolate methanetelluronate thymine allantoate 6-phosphate ECTO60_RS06945 L-malic succinate threonylcarbamoyladenosine deoxyribonucleoside in 23S rRNA acetamide dehydrogenase: ECTO60_RS04150 trimethylamine polyphosphate N-acetylglucosamine- allantoate semialdehyde 37 in tRNA ECTO60_RS11270 N-acetyl-D- allantoate acetaldehyde semialdehyde sn-glycero-3- 6-phosphate deiminase: allC 2-dehydropantoate THMPT a carboxylate acyl-CoA mannosamine deiminase: succinate- phosphoethanolamine N-acetylmannosamine deacetylase: nagA dehydrogenase: allC semialdehyde kinase: acetaldehyde ethanolamine (S)-ureidoglycine ECTO60_RS19600 N-acetylglucosamine- dehydrogenase: ECTO60_RS04155 dehydrogenase utilization ethanol (S)-malate 2605 (S)-ureidoglycine 6-phosphate (S)-ureidoglycine gabD UDP-N-acetyl-α-D-muramoyl- 2-amino-6-[1-hydroxyethyl]- [(R)-1- a single uridine dCMP D-ribulose β crotonyl-CoA N-acetyl-D- (acetylating): D-alanyl-D-alanine 2-keto-D-gluconate a double stranded DNA uroporphyrinogen-I coproporphyrinogen III 5,6-dihydrouracil a -D-galactoside deacetylase: nagA dehydrogenase aminohydrolase: L-alanyl-γ-D-glutamyl-L-lysine 7-methyl-7,8-dihydropterin aminoethyl]phosphonate stranded DNA in 23S rRNA 5-phosphate (S)-ureidoglycine ECTO60_RS18860 succinate 2,5-didehydrogluconate DNA/RNA mannosamine D-glucosamine EutG: eutG allE 2-amino-4-hydroxy-6- 23S rRNA 5'-deoxynucleotidase: NAD-dependent galactoside O- deoxyribonuclease IV: uroporphyrinogen phosphoribulokinase: porphyrinogen (S)-3- 6-phosphate aminohydrolase: 6-phosphate alcohol hydroxymethyldihydropteridine aminoalkylphosphonate reductase DkgB: dkgB nuclease SfsA: sfsA pseudouridine(2605) ECTO60_RS07655 dihydropyrimidine acetyltransferase: UDP-N-acetylmuramoyl- ECTO60_RS08285 decarboxylase: hemE ECTO60_RS01845 peroxidase: yfeX hydroxybutanoyl- N-acetylmannosamine- allE dehydrogenase (S)-ureidoglycolate diphosphokinase: folK N-acetyltransferase: phnO 2,5-didehydrogluconate deoxyribonuclease synthase RluB: rluB dehydrogenase lacA acetyl-CoA pyruvate tripeptide--D-alanyl-D- 2'-deoxycytidine β CoA 6-phosphate 2605 a 6-acetyl- - (S)-ureidoglycolate AdhP: adhP [1-(2-amino-7-methyl-4-oxo- [(1R)-1- reductase DkgA: dkgA I: endA a pseudouridine D-ribulose-1,5- subunit PreA: preA hydratase: fadB alanine ligase: murF a 5'-phosphooligonucleotide coproporphyrinogen I coproporphyrin III D-galactoside 2-epimerase: phosphate ureidoglycolate 7,8-dihydro-3H-pteridin- acetamidoethyl]phosphonate 2,5-didehydro-D-gluconate a 5'-phosphooligonucleotide in 23S rRNA bisphosphate uracil ECTO60_RS02540 α-D-glucosamine lyase: allA 6-yl)]ethyl diphosphate enoyl-CoA ureidoglycolate malate/lactate/ acetyltransferase: pta N-acetyl-D- 6-phosphate ethanol UDP-N-acetyl-α-D-muramoyl-L-alanyl- hydratase: dehydrogenase: ureidoglycolate phosphate glucosamine glyoxylate γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine fadJ allD dehydrogenase: glucosamine- acetyltransferase: L-carnitine degradation I 6-phosphate (S)-3- 6-phosphate ECTO60_RS07625 N-acetylglucosamine- malate/lactate/ ECTO60_RS16715 hydroxybutanoyl- deaminase: 2,5-diamino-6-(5- [(S)-1- dUMP dTMP ureidoglycolate ureidoglycolate D-carnitine phosphatidylglycerolphosphate (3-aminopropyl) (2-aminoethyl) glyoxylate a 5' triphospho- an α-limit dextrin maltose D-sedoheptulose CoA 6-phosphate nagB L-carnitine phospho-D-ribitylamino) 3-keto-L-gulonate dehydrogenase: dehydrogenase: acetyl phosphate degradation II (1-oleoyl, 2-palmitoyl) aminoethyl]phosphonate phosphonate phosphonate [mRNA] (S)-3- deacetylase: nagA pyrimidin-4(3H)-one glyoxylate/hydroxypyruvate 5'-deoxynucleotidase: 4-alpha- 5'-deoxynucleotidase: ECTO60_RS16715 allD glucosamine- bifunctional phosphatidylglycerophosphatase RNA 3-dehydro-L-gulonate alpha-glucosidase: fructokinase: hydroxybutanoyl- N-acetylglucosamine- propionate crotonobetaine/ aminoalkylphosphonate aminoalkylphosphonate aminoalkylphosphonate reductase GhrA: ghrA ECTO60_RS07655 glucanotransferase: ECTO60_RS07655 6-phosphate D-carnitine diaminohydroxyphosphoribosylaminopyrimidine B: pgpB pyrophosphohydrolase: 2-dehydrogenase: ECTO60_RS03195 ECTO60_RS18695 CoA 6-phosphate N-carbamoyl- kinase: tdcD carnitine-CoA N-acetyltransferase: phnO N-acetyltransferase: phnO N-acetyltransferase: phnO glyoxylate/hydroxypyruvate malQ deaminase: deaminase/5-amino-6-(5-phosphoribosylamino) [+ 2 isozymes] rppH ECTO60_RS00685 dehydrogeanse: deacetylase: nagA 2-oxoglycine 2'-deoxyuridine a debranched D-sedoheptulose thymidine ECTO60_RS24915 [+ 3 isozymes] ligase: caiC uracil reductase RibD: ribD 1-oleoyl-2-palmitoyl- [(1S)-1- (2-acetamidopropyl) (2-acetamidoethyl) reductase GhrB: ghrB a 5'-phospho- 2,3-dioxo- D-glucopyranose fadB 5-amino-6-(5-phospho- α-limit dextrin 1-phosphate D-glucosamine allantoin degradation phosphatidylglycerol acetamidoethyl]phosphonate phosphonate phosphonate glycolate [mRNA] L-gulonate 6-phosphate F6P acetate L-carnitine to glyoxylate I D-ribitylamino)uracil acetoacetyl-CoA (S)-(+)-allantoin acetyl-CoA C- carbamoyl oxamate L-carnitinyl-CoA carnitinyl-CoA allantoinase acetyltransferase: α-D-glucosamine phosphate dehydratase: L-carnitine AllB: allB ECTO60_RS07970 ECTO60_RS20595 3-dehydrocarnitine 6-phosphate carbamate kinase: CoA- [+ 3 isozymes] allantoate glucosamine- ECTO60_RS18060 transferase: 6-phosphate [+ 3 isozymes] caiB acetyl-CoA γ-butyrobetainyl- crotonobetainyl- deaminase: carbamate CoA CoA nagB trimethylaminoacetone glucosamine- (S)-ureidoglycolate 6-phosphate ureidoglycolate deaminase: crotonobetainyl- ECTO60_RS24915 CO lyase: allA 2 CoA glycine betaine dehydrogenase: 4-amino-4- F6P glyoxylate an L-sorbose 1-phosphate a branched- caiA deoxy-α-L- N-acetyl-α-D- D-fructose 1-phosphate chain pro arabinopyranosyl an aliphatic galactosamine methyl N,N'- N-acetyl-α-D-galactosamine 1-phosphate D-mannose 6-phosphate amino acid glycine betaine glycine maltose an an ditrans,octacis a sugar 6- a sugar 6- D-mannose D-fructose D-fructose D-fructose L-arabinose sulfonate 1-phosphate D-galactose galactitol 1- D-mannitol D-sorbitol diacetylchitobiose tetracycline (enterobacterial N-acetyl-α-D-galactosamine 1-phosphate an L-sorbose 1-phosphate an L-sorbose 1-phosphate an L-sorbose 1-phosphate molybdate N-acetyl-D- glutathione putrescine a branched- a branched- an L- 2-dehydro- a β- γ-butyrobetaine betaine glutamate M-antigen a maltodextrin oligopeptide oligopeptide phosphonate a carbohydrate -undecaprenyl phosphate phosphate 6-phosphate a lipopolysaccharide a lipopolysaccharide 1-phosphate 1-phosphate 1-phosphate phosphate 1-phosphate 6-phosphate a basic 6'-phosphate pro glutamate a purine a peptide a lyso- 3,5- α maltose 6'- common antigen) a sugar 6- a sugar 6- a sugar 6- a sugar 6- D-fructose 1-phosphate D-fructose lipid II (meso α α a C4- a C4- a C4- a C4- a C4- a C4- D-glucose 6- D-glucose 6- D-glucose 6- galactitol 1- D-mannitol D-glucosamine D-trehalose monomer a polysialic a tricarboxylate a microcin TET N-acetyl- -D- D-methionine phosphate a nucleoside a nucleoside a nucleoside a nucleoside a nucleoside D-fructose 1-phosphate D-fructose 1-phosphate D-fructose 1-phosphate a lipopolysaccharide glutamate glutamate D-glucose enterobactin muramate 6- -L- -L- ornithine chain chain 2-oxoglutarate sorbose 1- 3-deoxy-D- glucoside 6- L-carnitine 4-aminobutanoate 4-aminobutanoate a D- a macrolide a nucleotide a phospholipid a sulfonate a dicarboxylate ribonucleoside antibiotic phospholipid homoserine dimethoxytoluene phosphate -undecaprenyl phosphate phosphate phosphate phosphate 1-phosphate diaminopimelate L-arabinose D-glucose dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate phosphate phosphate phosphate phosphate 1-phosphate 6-phosphate N-acetylneuraminate N-acetylneuraminate N-acetylneuraminate amino acid D-gluconate D-gluconate D-gluconate N-acetyl-α-D- glycine betaine 4-aminobutanoate 6-phosphate undecaprenyl L-rhamnose pyrimidine acid galactosamine 2-nitroimidazole D-mannose 6-phosphate D-mannose 6-phosphate D-mannose 6-phosphate predicted D-mannose 6-phosphate D-galactose phosphate arabinopyranose arabinopyranose amino acid amino acid predicted phosphate a polysaccharide a polysaccharide gluconate phosphate microcin J25 chromate glucoronoside lactone diphosphate containing) predicted predicted predicted glucosamine predicted diphosphate PEP-driven predicted ABC predicted predicted predicted predicted 4-amino-4-deoxy- predicted predicted predicted predicted predicted predicted ABC PEP-driven ABC predicted predicted predicted predicted predicted predicted ABC predicted ABC predicted ABC transporter predicted ABC predicted ABC predicted ABC ABC transporter ABC ABC ABC ABC L-arabinose- PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven PEP-driven transporter transporter transporter ABC ABC PEP-driven PEP-driven PEP-driven PEP-driven transporter RS03955 RS24265 RS00200 RS18785 transporter of RS08180 RS05045 RS24375 RS25865 transporter of RS21375 RS02910 RS19710 RS11660 RS10790 RS24555 RS24340 RS05530 RS20075 RS02935 RS04440 RS18615 RS07175 RS21150 RS08265 RS23265 RS10660 RS02945 of D- RS02940 transporter of a transporter of a efflux transporter of RS07205 RS14730 RS00305 RS17500 RS11960 transporter RS20400 RS08335 RS17790 RS06995 RS07505 RS10250 RS17280 RS18665 RS06020 of a RS24275 RS17150 RS20430 RS22505 RS22630 RS17645 RS05150 RS07050 RS14570 RS06310 RS01220 RS00580 RS23260 RS08755 RS03960 RS23860 RS17380 RS02535 RS04170 RS21265 RS07620 RS01450 RS01560 RS21200 RS24895 RS14920 RS20575 RS22690 transporter RS22405 RS12100 RS06115 RS21950 RS08035 RS25955 RS08835 RS11685 transporter RS23870 RS16325 RS06185 RS15010 RS02645 RS15300 RS12345 transporter transporter of phosphoundecaprenol transporter transporter transporter transporter transporter transporter of an of N-acetyl- of D- transporter transporter transporter transporter transporter transporter of N,N'- of glycine phosphonate a carbohydrate mannose/ lipopolysaccharide lipopolysaccharide a lipopolysaccharide of L- branched- of glycine of maltose/a of an a tripeptide/an flippase of a sugar of a sugar of D-mannose of D-fructose of D-fructose of D-fructose aliphatic alpha-D- galactose/a of molybdate of glutathione of galactitol of D-mannitol of D-sorbitol diacetylchitobiose betaine/ D-fructose/ arabinose chain betaine maltodextrin oligopeptide oligopeptide a polysialic N-acetyl-α-D- N-acetyl-α-D-galactosamine L-sorbose N-acetyl-α-D-galactosamine L-sorbose sulfonate galactosamine methyl group D-glucose N-acetyl-D- α-L- α-L- a branched- a branched- 2-dehydro- L-proline a D- a peptide a lyso- 3,5- D-fructose D-glucose amino acid a C4- a C4- a C4- a C4- a C4- a C4- D-glucose D-glucose galactitol D-mannitol D-glucosamine N-acetylneuraminate N-acetylneuraminate N-acetylneuraminate a basic D-gluconate D-gluconate D-gluconate a β-glucoside pro glutamate trehalose L-rhamnose pyrimidine a tricarboxylate a microcin maltose (enterobacterial a sugar a sugar a sugar a sugar a nucleoside a nucleoside a nucleoside a nucleoside a nucleoside L-sorbose lipid II (meso L-arabinose D-galactose enterobactin muramate arabinopyranose arabinopyranose D-glucose 2-oxoglutarate L-sorbose N-acetyl-α-D- 4-aminobutanoate M-antigen glucoronoside a macrolide a nucleotide a phospholipid a sulfonate a dicarboxylate acid antibiotic phospholipid homoserine dimethoxytoluene galactosamine D-methionine D-fructose D-fructose L-sorbose D-fructose glutamate glutamate chain chain dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate dicarboxylate a polysaccharide a polysaccharide 3-deoxy-D- a purine phosphonate TET a carbohydrate 2-nitroimidazole common antigen) a lipopolysaccharide a lipopolysaccharide diaminopimelate ornithine amino acid N,N'- glucosamine L-carnitine glycine betaine 4-aminobutanoate 4-aminobutanoate microcin J25 chromate monomer lactone a sugar a sugar D-mannose D-mannose D-fructose D-mannose D-mannose D-fructose D-fructose D-fructose molybdate amino acid amino acid galactitol D-mannitol gluconate D-sorbitol maltose an 4-amino-4- a lipopolysaccharide L-arabinose N-acetyl-α-D- glutathione diacetylchitobiose γ-butyrobetaine glycine an ribonucleoside tetracycline -undecaprenyl D-mannose containing) an aliphatic methyl putrescine glutamate undecaprenyl a maltodextrin α-L- L-sorbose a branched- pro betaine oligopeptide oligopeptide deoxy- diphosphate sulfonate galactosamine D-galactose diphosphate arabinopyranosyl D-fructose chain glycine betaine ditrans,octacis D-mannose amino acid -undecaprenyl phosphate