Endometriosis for Dummies.Pdf
Total Page:16
File Type:pdf, Size:1020Kb
Load more
Recommended publications
-
The Male Reproductive System
Management of Men’s Reproductive 3 Health Problems Men’s Reproductive Health Curriculum Management of Men’s Reproductive 3 Health Problems © 2003 EngenderHealth. All rights reserved. 440 Ninth Avenue New York, NY 10001 U.S.A. Telephone: 212-561-8000 Fax: 212-561-8067 e-mail: [email protected] www.engenderhealth.org This publication was made possible, in part, through support provided by the Office of Population, U.S. Agency for International Development (USAID), under the terms of cooperative agreement HRN-A-00-98-00042-00. The opinions expressed herein are those of the publisher and do not necessarily reflect the views of USAID. Cover design: Virginia Taddoni ISBN 1-885063-45-8 Printed in the United States of America. Printed on recycled paper. Library of Congress Cataloging-in-Publication Data Men’s reproductive health curriculum : management of men’s reproductive health problems. p. ; cm. Companion v. to: Introduction to men’s reproductive health services, and: Counseling and communicating with men. Includes bibliographical references. ISBN 1-885063-45-8 1. Andrology. 2. Human reproduction. 3. Generative organs, Male--Diseases--Treatment. I. EngenderHealth (Firm) II. Counseling and communicating with men. III. Title: Introduction to men’s reproductive health services. [DNLM: 1. Genital Diseases, Male. 2. Physical Examination--methods. 3. Reproductive Health Services. WJ 700 M5483 2003] QP253.M465 2003 616.6’5--dc22 2003063056 Contents Acknowledgments v Introduction vii 1 Disorders of the Male Reproductive System 1.1 The Male -
Prolactin Level in Women with Abnormal Uterine Bleeding Visiting Department of Obstetrics and Gynecology in a University Teaching Hospital in Ajman, UAE
Prolactin level in women with Abnormal Uterine Bleeding visiting Department of Obstetrics and Gynecology in a University teaching hospital in Ajman, UAE Jayakumary Muttappallymyalil1*, Jayadevan Sreedharan2, Mawahib Abd Salman Al Biate3, Kasturi Mummigatti3, Nisha Shantakumari4 1Department of Community Medicine, 2Statistical Support Facility, CABRI, 4Department of Physiology, Gulf Medical University, Ajman, UAE 3Department of OBG, GMC Hospital, Ajman, UAE *Presenting Author ABSTRACT Objective: This study was conducted among women in the reproductive age group with abnormal uterine bleeding (AUB) to determine the pattern of prolactin level. Materials and Methods: In this study, a total of 400 women in the reproductive age group with AUB attending GMC Hospital were recruited and their prolactin levels were evaluated. Age, marital status, reproductive health history and details of AUB were noted. SPSS version 21 was used for data analysis. Descriptive statistics was performed to describe the population, and inferential statistics such as Chi-square test was performed to find the association between dependent and independent variables. Results: Out of 400 women, 351 (87.8%) were married, 103 (25.8%) were in the age group 25 years or below, 213 (53.3%) were between 26-35 years and 84 (21.0%) were above 35 years. Mean age was 30.3 years with a standard deviation 6.7. The prolactin level ranged between 15.34 mIU/l and 2800 mIU/l. The mean and SD observed were 310 mIU/l and 290 mIU/l respectively. The prolactin level was high among AUB patients with inter-menstrual bleeding compared to other groups. Additionally, the level was high among women with age greater than 25 years compared to those with age less than or equal to 25 years. -
Vaginitis and Abnormal Vaginal Bleeding
UCSF Family Medicine Board Review 2013 Vaginitis and Abnormal • There are no relevant financial relationships with any commercial Vaginal Bleeding interests to disclose Michael Policar, MD, MPH Professor of Ob, Gyn, and Repro Sciences UCSF School of Medicine [email protected] Vulvovaginal Symptoms: CDC 2010: Trichomoniasis Differential Diagnosis Screening and Testing Category Condition • Screening indications – Infections Vaginal trichomoniasis (VT) HIV positive women: annually – Bacterial vaginosis (BV) Consider if “at risk”: new/multiple sex partners, history of STI, inconsistent condom use, sex work, IDU Vulvovaginal candidiasis (VVC) • Newer assays Skin Conditions Fungal vulvitis (candida, tinea) – Rapid antigen test: sensitivity, specificity vs. wet mount Contact dermatitis (irritant, allergic) – Aptima TMA T. vaginalis Analyte Specific Reagent (ASR) Vulvar dermatoses (LS, LP, LSC) • Other testing situations – Vulvar intraepithelial neoplasia (VIN) Suspect trich but NaCl slide neg culture or newer assays – Psychogenic Physiologic, psychogenic Pap with trich confirm if low risk • Consider retesting 3 months after treatment Trichomoniasis: Laboratory Tests CDC 2010: Vaginal Trichomoniasis Treatment Test Sensitivity Specificity Cost Comment Aptima TMA +4 (98%) +3 (98%) $$$ NAAT (like GC/Ct) • Recommended regimen Culture +3 (83%) +4 (100%) $$$ Not in most labs – Metronidazole 2 grams PO single dose Point of care – Tinidazole 2 grams PO single dose •Affirm VP III +3 +4 $$$ DNA probe • Alternative regimen (preferred for HIV infected -
LNG-IUS) in Patients Affected by Menometrorrhagia, Dysmenorrhea and Adenomimyois: Clinical and Ultrasonographic Reports
European Review for Medical and Pharmacological Sciences 2021; 25: 3432-3439 The treatment with Levonorgestrel Releasing Intrauterine System (LNG-IUS) in patients affected by menometrorrhagia, dysmenorrhea and adenomimyois: clinical and ultrasonographic reports F. COSTANZI, M.P. DE MARCO, C. COLOMBRINO, M. CIANCIA, F. TORCIA, I. RUSCITO, F. BELLATI, A. FREGA, G. COZZA, D. CASERTA Department of Surgical and Medical Sciences and Translational Medicine, Sant’Andrea University Hospital, Sapienza University of Rome, Rome, Italy Abstract. – OBJECTIVE: Adenomyosis is p=0.025; p=0.014). The blood loss decreased the consequence of the myometrial invasion significantly in both the cohorts (p<0.001) and by endometrial glands and stroma. Transvag- particularly in adenomyotic patients. Pain relief inal ultrasonography plays a decisive role in was observed in all the patients (p<0.001). the diagnosis and monitoring of this patholo- CONCLUSIONS: LNG-IUS can be considered gy. Our study aims to evaluate the efficacy of an effective treatment for managing symptoms LNG-IUS (Levonorgestrel Releasing Intrauter- and improving uterine morphology. ine System) as medical therapy. We analyzed both clinical symptoms and ultrasonograph- Key Words: ic aspects of menometrorrhagia and dysmen- Benign disease of uterus, Dysmenorrhea, Gyne- orrhea in patients with adenomyosis and the cologic imaging, Leiomyomas of the uterus/adeno- control group. myosis. PATIENTS AND METHODS: A prospective co- hort study was carried out on 28 patients suf- fering from symptomatic adenomyosis treat- ed with LNG-IUS. Adenomyosis was diagnosed Introduction through transvaginal ultrasonography by an ex- pert sonographer. A control group of 27 symp- Adenomyosis is a benign gynecological dis- tomatic patients (menorrhagia and dysmenor- ease with a large variety of clinical manifestation; rhea) without a transvaginal ultrasonograph- the most frequent include menorrhagia, metror- ic diagnosis of adenomyosis was treated in the rhagia, dysmenorrhea and chronic pelvic pain1. -
American Family Physician Web Site At
Diagnosis and Management of Adnexal Masses VANESSA GIVENS, MD; GREGG MITCHELL, MD; CAROLYN HARRAWAY-SMITH, MD; AVINASH REDDY, MD; and DAVID L. MANESS, DO, MSS, University of Tennessee Health Science Center College of Medicine, Memphis, Tennessee Adnexal masses represent a spectrum of conditions from gynecologic and nongynecologic sources. They may be benign or malignant. The initial detection and evaluation of an adnexal mass requires a high index of suspicion, a thorough history and physical examination, and careful attention to subtle historical clues. Timely, appropriate labo- ratory and radiographic studies are required. The most common symptoms reported by women with ovarian cancer are pelvic or abdominal pain; increased abdominal size; bloating; urinary urgency, frequency, or incontinence; early satiety; difficulty eating; and weight loss. These vague symptoms are present for months in up to 93 percent of patients with ovarian cancer. Any of these symptoms occurring daily for more than two weeks, or with failure to respond to appropriate therapy warrant further evaluation. Transvaginal ultrasonography remains the standard for evaluation of adnexal masses. Findings suggestive of malignancy in an adnexal mass include a solid component, thick septations (greater than 2 to 3 mm), bilaterality, Doppler flow to the solid component of the mass, and presence of ascites. Fam- ily physicians can manage many nonmalignant adnexal masses; however, prepubescent girls and postmenopausal women with an adnexal mass should be referred to a gynecologist or gynecologic oncologist for further treatment. All women, regardless of menopausal status, should be referred if they have evidence of metastatic disease, ascites, a complex mass, an adnexal mass greater than 10 cm, or any mass that persists longer than 12 weeks. -
Intermenstrual Bleeding (Bleeding Between Periods)
Intermenstrual Bleeding (Bleeding between periods) What is Intermenstrual bleeding? This is unscheduled bleeding that can occur in between periods. There are many different causes of bleeding between periods but seek medical advice if you are experiencing this, even if it is for reassurance in many situations. What is the nature of bleeding? Bleeding that occurs randomly without any relation to your monthly period should not be ignored, unless the cause is known. The bleeding may be light blood, spotting, a bloody or dark brown vaginal loss or heavy bleeding mimicking a period. Mid cycle pain and bleeding Mittelschmerz is one-sided, lower abdominal pain associated with ovulation, about 14 days before your next menstrual period. In most cases, mittelschmerz does not require medical attention and may be associated with light vaginal bleeding for a day or so. It may not occur every month. If you are concerned, seek advice. Spotting in the lead up to or at the end of the period Usually, this just suggests that levels of progesterone fall slightly more slowly in some cycles and can lead to spotting seen in the lead up to the proper menstrual flow. This is usually not a concern. Spotting or a brown vaginal loss as the period finishes is also not abnormal, unless lasting for days or associated with other symptoms. (See information on a normal menstrual cycle under the leaflet on Irregular Periods) What are the possible causes of bleeding between periods? (not an exhaustive list) Hormonal contraceptives, such as the combined or progesterone only pill, implant, injection, intrauterine system, patch, ring can all cause bleeding between cycles, especially in the first few months of starting them. -
Gynecology Revised: 11/2013
Emergency Medical Training Services Emergency Medical Technician – Paramedic Program Outlines Outline Topic: Gynecology Revised: 11/2013 21 questions on exam 8 from this outline • Menstruation - normal periodic discharge of blood, mucus, and cellular debris from uterus. The normal menstrual cycle lasts about 28 days. 25 to 60mL average flow. Flow lasts usually 4 to 6 days. Lining of the uterus is called endometrium. Onset of menses (menarche) begins around 12 years of age. Menopause starts at age 47 on average. But can range from 30 to 60 years of age. Estrogen stimulates endometrium to grow and increase in thickness. • Ovaries contain about 5 million cells to make oocytes (immature ova/eggs). At puberty 350,000 are present. In a lifetime the ovary will release 400 through menstruation • The release of the egg is termed ovulation. • The pituitary released FSH to stimulate the ovaries to produce estrogen. As a result of the estrogen builds up in blood stream just before ovulation the pituitary releases luteinizing hormone to initiate the release of eggs. • Up to seven days after ovulation (day 21) the uterus is ready to receive an embryo if fertilization has happened. • Recap: Day 14 ovulation. Up to day 21 fertilization window, day 22 thru 28 period if not pregnant. GYN emergencies are classified as: Non-traumatic • PID - infection entered the pelvis cavity. Most common causes are non-sterile exam equipment and if sexually transmitted is N. Gonorrhea and Chlamydia. Lower abdominal pain, hurts with sex, vaginal discharge and additional bleeding after period is over. Antibiotic therapy is needed. • Ovarian cyst - can be a bleeding/shock emergency. -
Abnormal Uterine Bleeding: a Management Algorithm
J Am Board Fam Med: first published as 10.3122/jabfm.19.6.590 on 7 November 2006. Downloaded from EVIDENCED-BASED CLINICAL MEDICINE Abnormal Uterine Bleeding: A Management Algorithm John W. Ely, MD, MSPH, Colleen M. Kennedy, MD, MS, Elizabeth C. Clark, MD, MPH, and Noelle C. Bowdler, MD Abnormal uterine bleeding is a common problem, and its management can be complex. Because of this complexity, concise guidelines have been difficult to develop. We constructed a concise but comprehen- sive algorithm for the management of abnormal uterine bleeding between menarche and menopause that was based on a systematic review of the literature as well as the actual management of patients seen in a gynecology clinic. We started by drafting an algorithm that was based on a MEDLINE search for rel- evant reviews and original research. We compared this algorithm to the actual care provided to a ran- dom sample of 100 women with abnormal bleeding who were seen in a university gynecology clinic. Discrepancies between the algorithm and actual care were discussed during audiotaped meetings among the 4 investigators (2 family physicians and 2 gynecologists). The audiotapes were used to revise the algorithm. After 3 iterations of this process (total of 300 patients), we agreed on a final algorithm that generally followed the practices we observed, while maintaining consistency with the evidence. In clinic, the gynecologists categorized the patient’s bleeding pattern into 1 of 4 types: irregular bleeding, heavy but regular bleeding (menorrhagia), severe acute bleeding, and abnormal bleeding associated with a contraceptive method. Subsequent management involved both diagnostic and treatment interven- tions, which often occurred simultaneously. -
Too Much, Too Little, Too Late: Abnormal Uterine Bleeding
Too much, too little, too late: Abnormal uterine bleeding Jody Steinauer, MD, MAS July, 2015 The Questions • Too much (& too early or too late) – Differential and approach to work‐up – Does she need an endometrial biopsy (EMB)? – Does she need an ultrasound? – How do I stop peri‐menopausal bleeding? – Isn’t it due to the fibroids? • Too fast: She’s hemorrhaging—what do I do? • Too little: A quick review of amenorrhea Case 1 A 46 yo G3P2T1 reports her periods have become 1. What term describes increasingly irregular and heavy her symptoms? over the last 6‐8 months. 2. Physiologically, what Sometimes they come 2 times causes this type of per month and sometimes there bleeding pattern? are 2 months between. LMP 2 3. What is the months ago. She bleeds 10 days differential? with clots and frequently bleeds through pads to her clothes. She occasionally has hot flashes. She also has diabetes and is obese. Q1: In addition to a urine pregnancy test and TSH, which of the following is the most appropriate test to obtain at this time? 1. FSH 2. Testosterone & DHEAS 3. Serum beta‐HCG 4. Transvaginal Ultrasound (TVUS) 5. Endometrial Biopsy (EMB) Terminology: What is abnormal? • Normal: Cycle= 28 days +‐ 7 d (21‐35); Length=2‐7 days; Heaviness=self‐defined • Too little bleeding: amenorrhea or oligomenorrhea • Too much bleeding: Menorrhagia (regular timing but heavy (according to patient) OR long flow (>7 days) • Irregular bleeding: Metrorrhagia, intermenstrual or post‐ coital bleeding • Irregular and Excessive: Menometrorrhagia • Preferred term for non‐pregnant bleeding issues= Abnormal Uterine Bleeding (AUB) – Avoid “DUB” ‐ dysfunctional uterine bleeding. -
Selected Topics in WOMEN’S HEALTH
www.bpac.org.nz keyword: womenshealth Selected topics in WOMEN’S HEALTH Laboratory investigation of amenorrhoea Polycystic ovary syndrome An overview of dysfunctional uterine bleeding Perimenopause and menopause Sexual dysfunction - loss of libido 8 | September 2010 | best tests Amenorrhoea Amenorrhoea is the absence of menstruation flow. It can Causes of primary amenorrhoea2 be classified as either primary or secondary,1 relative to menarche: ■ Hypergonadotropic hypogonadism/primary hypogonadism/gonadal failure: ■ Primary amenorrhoea: absence of menses by age 16 years in a female with appropriate development – Abnormal sex chromosomes e.g. Turner of secondary sexual characteristics; or absence syndrome of menses by age 13 years and no other pubertal – Normal sex chromosomes e.g. premature maturation2 ovarian failure ■ Secondary amenorrhoea: lack of menses in a ■ Hypogonadotropic hypogonadism/secondary previously menstruating, non-pregnant female, for hypogonadism: 2 greater than six months – In many cases this may be due to a familial delay in puberty and growth. Other causes include congenital abnormalities Primary amenorrhoea e.g. isolated GnRH deficiency, acquired Key messages: lesions, endocrine disturbance, tumour, systemic illness or eating disorder. ■ The most common cause of primary amenorrhoea in a female with no secondary sexual characteristics ■ Eugonadism: is a constitutional delay in growth and puberty. – Anatomic e.g. congenital absence of the In the first instance, watchful waiting is the most uterus and vagina, intersex -
Module 3: Reproductive Tract Infections
Reproductive Tract Infections Reproductive Health Epidemiology Series Module 3 2003 Department of Health and Human Services REPRODUCTIVE TRACT INFECTIONS REPRODUCTIVE HEALTH EPIDEMIOLOGY SERIES: MODULE 3 June 2003 The United States Agency for International Development (USAID) provided funding for this project through a Participating Agency Service Agreement with CDC (936-3038.01). REPRODUCTIVE HEALTH EPIDEMIOLOGY SERIES—MODULE 3 REPRODUCTIVE TRACT INFECTIONS Divya A. Patel, MPH Nancy M. Burnett, BS Kathryn M. Curtis, PhD Technical Editors Susan Hillis, PhD Polly Marchbanks, PhD U.S. Department of Health and Human Services Centers for Disease Control and Prevention National Center for Chronic Disease Prevention and Health Promotion Division of Reproductive Health Atlanta, Georgia, U.S.A. 2003 CONTENTS Learning Objectives .........................................................................................1 Overview of Reproductive Tract Infections (RTIs) ............................................3 Prevalence of RTIs .......................................................................................3 What Are the Most Commonly Occurring RTIs in Developing Countries? ....4 Sequelae of Untreated RTIs .........................................................................4 How Are RTIs Transmitted? ........................................................................7 How Are RTIs and Their Sequelae Linked With Key Health-Related Development Programs? ...............................................8 General Model of the Epidemiology -
Abnormal Uterine Bleeding Sorting It All
Abnormal Uterine Bleeding- Sorting It All Out Patricia Geraghty MSN, FNP-BC, WHNP Disclosures • Abbvie Inc. Speakers Bureau, Advisory Board • Therapeutics MD Speaker, Advisory Board • Sharecare Inc. Advisory Board • No commercial material is included in this presentation. All citations are from peer-reviewed academic sources. The speaker has not been paid by any outside entity for this presentation or any presentation on this topic. Objectives • Define the variation in normal uterine bleeding. • Distinguish the etiology of abnormal uterine bleeding according to the PALM-COEIN classification system. • Determine age appropriate approach to the diagnostic work- up of abnormal uterine bleeding. • Select the management strategies for specific abnormal bleeding etiology utilizing an understanding of structural and hormonal interventions. • Differentiate the interventions for acute heavy uterine bleeding. Defining Normal • Normal menses (95% of population)1 • Frequency every 24 to 38 days • Duration 4 to 6 days • Blood volume 20-80 cc; requires change of protection every 3 to 6 hours on heaviest day(s) • Tapers over following days • 50% volume loss is vaginal and cervical secretions • Regular -difference between longest and shortest interval < 20 days in 12 month period 1Fraser I, et al. Fertil Steril. 2007;87(3):466-476. ACOG Committee Practice Bulletin. Ob Gyn. 2012; 120(1):197-206. Sharp HT, Johnson JV et al. Obstet Gynecol. 2017 Apr;129(4):603-607 Updating Terminology Dimension < 5th Percentile 5th-95th Percentile >95th Percentile Regularity cycle- Absent Regular (variation Irregular (typical variation to-cycle over 12 Amenorrhea 2 ± 20d) >20d between mos longest/shortest interval) Intermenstrual Frequency Infrequent (>38d) Normal Frequent (<24d) Oligomenorrhea Polymenorrhea Duration Shortened (< 4.5d) Normal Prolonged (> 8d) Hypomenorrhea Hypermenorrhea Volume Light (< 5 cc) Normal Heavy (> 80 cc) Hypomenorrhea Menorrhagia Combination Irregular and Heavy Menometrorrhagia Sharp HT, Johnson JV et al.