ISSN: 0258-851X

International Journal of Experimental and Clinical Pathophysiology and Drug Research

Volume 28, Number 5, September-October 2014

Contents

Reviews

The WT1 Gene – Its Role in Tumourigenesis and Prospects for Immunotherapeutic Advances. I. LINDSTEDT, M. A. LINDGREN, E. ANDERSSON, W. ENGSTRÖM (Uppsala, Sweden) ...... 675

Cell Adhesion Molecules and In Vitro Fertilization. M. SIMOPOULOU, E. NIKOLOPOULOU, A. DIMAKAKOS, K. CHARALABOPOULOS, M. KOUTSILIERIS (Athens; Alexandroupolis, Greece) ...... 683

Experimental Studies

Effect of GPIIb/IIIa Inhibition with Eptifibatide or Tirofiban on the Expression of Cellular Adhesion Molecules on Monocytes. S. SWOBODA, T. WALTER, S. LANG, H.-P. WENDEL, M. E. BEYER, E. GRIESEL, H.-M. HOFFMEISTER, J. GRUETTNER (Heidelberg; Mannheim; Tuebingen; Kirchheim; Solingen, Germany)...... 691

Improved Hematopoiesis in GS-Nitroxide (JP4-039)-treated Mouse Long-term Bone Marrow Cultures and Radioresistance of Derived Bone Marrow Stromal Cell Lines. A. SHINDE, M. W. EPPERLY, S. CAO, D. HOLT, J. GOFF, D. SHIELDS, D. FRANICOLA, P. WIPF, H. WANG, J. S. GREENBERGER (Pittsburgh, PA, USA)...... 699

Mutation of Murine Sox4 Untranslated Regions Results in Partially Penetrant Perinatal Lethality. W. GUY WILES IV, Z. MOU, Y. DU, A. B. LONG, C. D. SCHARER, B. BILIR, D. D. SPYROPOULOS, N. A. JENKINS, N. G. COPELAND, W. D. MARTIN, C. S. MORENO (Atlanta, GA; Bethesda, MD; Charleston, SC; Houston, TX, USA) ...... 709

Inhibitory Effects of p-Cresol and p-Hydroxy Anisole Dimers on Expression of the Cyclooxygenase-2 Gene and Lipopolysaccharide-stimulated Activation of Nuclear Factor-κB in RAW264.7 Cells. Y. MURAKAMI, A. KAWATA, S. ITO, T. KATAYAMA, S. FUJISAWA (Saitama; Tokyo, Japan) ...... 719

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Perfusion of a Cerebral Protective Solution Enhances Neuroprotection in a Rabbit Model of Occlusion- Reperfusion: Prolonged Cerebral Dormancy Time. L. YE, A. HUA, B. DAI, T. LU, Z. ZHANG, M. YE, M. WEINTRAUB, Q. Q. LI (Nanning, PR China; Bethesda, MD, USA) ...... 727

Bone Substitutes Enhance Osteogenic Differentiation of Mesenchymal Stem Cells in Three-dimensional Scaffolds. H. HANKEN, J. ALPERS, M. BÖBEL, M. WÖLTJE, P. HARTJEN, R. E. FRIEDRICH, O. JUNG, C. RENDENBACH, A. GRÖBE, M. HEILAND, A. AL-DAM, W. EICHHORN, R. SMEETS (Hamburg; Aachen, Germany)...... 733

The Success Rate in a Complicated Spatial Memory Test Is Determined by Age, Sex, Life History and Search Strategies in Cynomolgus Monkeys. H. S. DARUSMAN, O. KALLIOKOSKI, D. SAJUTHI, S. J. SCHAPIRO, A. GJEDDE, J. HAU (Copenhagen; Aarhus, Denmark; Bogor, Indonesia; Montreal, QC, Canada; Bastrop, TX; Baltimore, MD, USA)...... 741

Expression of Livin and the Inhibition of Tumor Progression by Livin Silencing in Laryngohypopharyngeal Cancer. T. M. YOON, S.-A. KIM, D. H. LEE, J. K. LEE, Y.-L. PARK, K.-H. LEE, I.-J. CHUNG, Y.-E. JOO, S. C. LIM (Gwanju, South Korea)...... 751

Validation of an HPV16-mediated Carcinogenesis Mouse Model. K. DE AZAMBUJA, P. BARMAN, J. TOYAMA, D. ELASHOFF, G. W. LAWSON, L. K. WILLIAMS, K. CHUA, D. LEE, J. J. KEHOE, A. BRODKORB, R. SCHWIEBERT, S. KITCHEN, A. BHIMANI, D. J. WILEY (Los Angeles, CA; Houston, TX, USA; Fermoy, Ireland)...... 761

Heparanase, a Potential Marker for Premalignant Oral Cavity Cancer. Y. LEISER, D. SHILO, I. A. EL NAAJ, A. RACHMIEL (Haifa, Israel) ...... 769

Establishment of Nude Mice with Complete Loss of Lymphocytes and NK Cells and Application for In Vivo Bio-imaging. R. KARIYA, K. MATSUDA, K. GOTOH, K. VAETEEWOOTTACHARN, S. HATTORI, S. OKADA (Kumamoto, Japan) ...... 779

Efficient Utilization of Licorice Root by Alkaline Extraction. H. OHNO, S. MIYOSHI, D. ARAHO, T. KANAMOTO, S. TERAKUBO, H. NAKASHIMA, T. TSUDA, K. SUNAGA, S. AMANO, E. OHKOSHI, H. SAKAGAMI, K. SATOH, M. YAMAMOTO (Tokyo; Kanagawa; Saitama, Japan) ...... 785

Influence of Static Magnetic Fields Combined with Human Insulin-like Growth Factor 1 on Human Satellite Cell Cultures. R. BIRK, J. U. SOMMER, D. HAAS, A. FABER, C. ADERHOLD, J. D. SCHULTZ, K. HOERMANN, J. STERN-STRAETER (Mannheim, Germany)...... 795

Healthy Lung Tissue Response to Mechanical Ventilation in an Experimental Porcine Model. J. FREMUTH, J. KOBR, K. PIZINGEROVA, L. SASEK, P. JEHLICKA, J. ZAMBORYOVA, O. HESS, J. VRZALOVA, J. RACEK, Z. TONAR (Pilsen, Czech Republic) ...... 803

Evaluation of Hirsutella sinensis Mycelium on Food Safety and Anti-hepatoma Activity in an Animal Model. H.-S. SHANG, J. CHOU, M.-F. WU, Y.-L. SHIH, M.-Y. YEH, H.-Y. CHUNG, H.-F. LU, N.-C. LIAO, J. Y. LIU, S.-C. HSUEH, J.-G. CHUNG (Taipei; New Taipei City; Houlong; Taichung, Taiwan, ROC)...... 811

Sodium Caseinate Induces Increased Survival in Leukaemic Mouse J774 Model. Y. CÓRDOVA- GALAVIZ, E. LEDESMA-MARTÍNEZ, I. AGUÍÑIGA-SÁNCHEZ, G. SOLDEVILA-MELGAREJO, I. SOTO-CRUZ, B. WEISS-STEIDER, E. SANTIAGO-OSORIO (Mexico City, Mexico) ...... 819 Contents continued on the preceding page Contents continued

The Expression of MTNR3 and Nuclear Receptors in Murine Leucocytes. V. CERNYSIOV, R. BOZAITE, M. MAURICAS, I. GIRKONTAITE (Vilnius, Lithuania) ...... 827

Influence of Circadian Time and Lighting Conditions on Expression of Melatonin Receptors 1 and 2 in Murine Lymphocytes. V. CERNYSIOV, R. BOZAITE, M. MAURICAS, I. GIRKONTAITE (Vilnius, Lithuania) ...... 831

Evaluation of the Immunological Cellular Response of Cebus apella Exposed to the Carcinogen ® N-Methyl-N-nitrosourea and Treated with CANOVA . D. C. AZEVEDO FEIO, J. A. PEREIRA CARNEIRO MUNIZ, R. CARVALHO MONTENEGRO, R. RODRIGUEZ BURBANO, L. CARDOSO DE BRITO JUNIOR, P. D. LIMA DE LIMA (Belém, PA; Ananindeua, PA, Brazil) ...... 837

The Effect of Common Antineoplastic Agents on Induction of Apoptosis in Canine Lymphoma and Leukemia Cell Lines. A. PAWLAK, A. RAPAK, I. ZBYRYT, B. OBMIŃSKA-MRUKOWICZ (Wroclaw, Poland) ...... 843

Alterations in miRNA Expression Patterns in Whole Blood of OSCC Patients. J. RIES, E. VAIRAKTARIS, R. KINTOPP, C. BARAN, F. W. NEUKAM, E. NKENKE (Erlangen; Halle, Germany; Athens, Greece) ...... 851

Use of Surgery and Carboplatin in Feline Malignant Mammary Gland Neoplasms with Advanced Clinical Staging. C. BONOLO DE CAMPOS, F. CAMARGO NUNES, G. EUNICE LAVALLE, G. DANTAS CASSALI (Jaboticabal; Belo Horizonte, Brazil)...... 863

Additional Compensatory Mechanisms Altering Antisense Oligonucleotide Suppression of BCL2: Effects upon AKT1 and STAT3. M. RUBENSTEIN, C. M. P. HOLLOWELL, P. GUINAN (Chicago, IL, USA)...... 867

VEGF and 17-β-estradiol Levels After Tamoxifen Administration in Canine Hepatoid Gland Adenomas and Hepatoid Gland Epitheliomas. A. SOBCZYŃSKA-RAK, A. BRODZKI (Lublin, Poland) ...... 871

Corticosterone Metabolites Originating as a Consequence of Solvated Electron (e–aq) Emission. E. BRENN, G. MITULOVIĆ, R.-M. QUINT, N. GETOFF (Vienna, Austria) ...... 879

The Relationship Between ACE Polymorphism and Panic Disorder. S. GULEC-YİLMAZ, H. GULEC, A. BURAK DALAN, B. CETİN, O. TİMİRCİ-KAHRAMAN, D. BİLGE OGUT, H. ATASOY, G. ARIKAN DİRİMEN, G. INAL GULTEKİN, T. ISBİR (Istanbul, Turkey) ...... 885

Phenethyl Isothiocyanate Inhibits In Vivo Growth of Subcutaneous Xenograft Tumors of Human Malignant Melanoma A375.S2 Cells. W.-Y. NI, H.-F. LU, S.-C. HSU, Y.-P. HSIAO, K.-C. LIU, J.-Y. LIU, B.-C. JI, S.-C. HSUEH, F.-M. HUNG, H.-S. SHANG, J.-G. CHUNG (Caotun; Taipei; Taichung; Changhua, Taiwan, ROC)...... 891

Effects of TiO2 Nano Glass Ionomer Cements Against Normal and Cancer Oral Cells. R. GARCIA- CONTRERAS, R. J. SCOUGALL-VILCHIS, R. CONTRERAS-BULNES, Y. KANDA4, H. NAKAJIMA, H. SAKAGAMI (Toluca, Mexico; Saitama, Japan)...... 895

Mn Complex-mediated Enhancement of Antitumor Response Through Modulating Myeloid-derived Suppressor Cells in Drug-resistant Tumor. S. DAS, K. BANERJEE, S. ROY, S. MAJUMDER, M. CHATTERJEE, S. MAJUMDAR, S. K. CHOUDHURI (Kolkata, India)...... 909

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Association of SUMO4 M55V and -94Ins/Del Gene Variants with Type-2 Diabetes. S. SOZEN, C. HOROZOGLU, E. S. BIRELLER, Z. KARAALI, B. CAKMAKOGLU (Istanbul, Turkey) ...... 919

Synergistic Effect of Sorafenib with Ionizing Radiation on Human Oral Cancer Cells. F.-T. HSU, B. CHANG, I-T. CHIANG, T.-H. WU, J.-J. HWANG (Taipei; Taichung, Taiwan, ROC)...... 925

Lipid Lipoprotein Profile Alterations in Greek Infertile Women with Polycystic Ovaries: Influence of Adipocytokines Levels. I. TSOUMA, E. KOUSKOUNI, S. DEMERIDOU, M. BOUTSIKOU, D. HASSIAKOS, A. CHASIAKOU, S. HASSIAKOU, V. GENNIMATA, S. BAKA (Athens, Greece) ...... 935

Clinical Studies

Progressive Multifocal Leukoencephalopathy – A Case Report and Review of the Literature. E. SMOLLE, A. TROJAN, S. J. SCHUSTER, J. HAYBAECK (Graz, Austria; Zurich, Switzerland; Philadelphia, PA, USA) ...... 941

Diffuse-type Tenosynovial Giant Cell Tumor with t(1;17)(p13;p13) and Trisomy 5. J. NISHIO, Y. KAMACHI, H. IWASAKI, M. NAITO (Fukuoka, Japan)...... 949

Urinary Neopterin Concentrations During Combination Therapy with Cetuximab in Previously Treated Patients with Metastatic Colorectal Carcinoma. B. MELICHAR, H. KALÁBOVÁ, L. KUJOVSKÁ KRČMOVÁ, S. VIPIN TRIVEDI, P. KRÁLÍČKOVÁ, E. MALÍŘOVÁ, M. PECKA, H. ŠTUDENTOVÁ, M. ZEZULOVÁ, P. HOLEČKOVÁ, D. SOLICHOVÁ (Olomouc; Hradec Králové, Czech Republic).... 953

Successful Treatment of Panton-Valentine Leukocidin-expressing Staphylococcus aureus-associated Pneumonia Co-infected with Influenza Using Extracorporeal Membrane Oxygenation. N. FUJISAKI, A. TAKAHASHI, T. ARIMA, T. MIZUSHIMA, K. IKEDA, H. KAKUCHI, A. NAKAO, J. KOTANI, K. SAKAIDA (Nishinomiya; Funabashi, Japan)...... 961

Effects of Interleukin-10 Polymorphisms and Smoking on the Risk of Gastric Cancer in Taiwan. W.- H. KUO, C.-Y. HUANG, C.-K. FU, Y.-H. HSIEH, C.-H. LIAO, C.-M. HSU, Y.-K. HUANG, C.-W. TSAI, W.-S. CHANG, D.-T. BAU (Kaoshiung; Taichung; Taipei, Taiwan, ROC) ...... 967

Anger in Health, Benign Breast Disease and Breast Cancer: A Prospective Case–Control Study. A. BRUNO, G. PANDOLFO, G. SCIMECA, V. LEONARDI, C. CEDRO, S. RACCHIUSA, R. A. ZOCCALI, M. R. A. MUSCATELLO (Messina, Italy) ...... 973

Complementary Medicine Down-regulates Side-effects of Hormone Therapy in Prostate Cancer Patients. J. BEUTH, R. VAN LEENDERT, K. PEMPELFORT, B. SCHNEIDER, C. GRUND, U. ENGELMANN (Cologne; Düsseldorf; Hannover, Germany) ...... 979

The Evaluation of Angiotensin-converting Enzyme (ACE) Gene I/D and IL-4 Gene Intron 3 VNTR Polymorphisms in Coronary Artery Disease. N. BASOL, A. CELIK, N. KARAKUS, S. D. OZSOY, S. YIGIT (Tokat, Turkey) ...... 983

Leptin Levels in Women with Polycystic Ovaries Undergoing Ovarian Stimulation: Relation to Lipoprotein Profiles. I. TSOUMA, E. KOUSKOUNI, V. GENNIMATA, S. DEMERIDOU, M. BOUTSIKOU, V. GRIGORIOU, A. CHASIAKOU, S. HASSIAKOU, S. BAKA (Athens, Greece)...... 989

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Postsurgical Pain Related to Breast Implant: Reduction with Lipofilling Procedure. R. CUOMO, I. ZERINI, G. BOTTERI, L. BARBERI, G. NISI, C. D’ANIELLO (Siena, Italy) ...... 993

Surgical Treatment to Aid Patients with Colorectal Perforation. H. ONISHI, K. SUMIYOSHI, R. TERASAKA, M. KATANO (Fukuoka, Japan) ...... 997

EORTC QLQ-BM22 Quality of Life Evaluation and Pain Outcome in Patients with Bone Metastases from Breast Cancer Treated with Zoledronic Acid. D.-C. YEH, D.-R. CHEN, T.-Y. CHAO, S.-C. CHEN, H.-C. WANG, K.-M. RAU, Y.-H. FENG, Y.-C. CHANG, K.-D. LEE, F. OU-YANG, W.-H. KUO, K.-J. CHANG, Y.-C. LIN, L.-M. TSENG, M.-F. HOU (Taichung; Changhua; New Taipei City; Taipei; Kaohsiung; Tainan; Chiayi; Taoyuan, Taiwan, ROC) ...... 1001