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Recommended Citation "Washington University Record, September 14, 2001" (2001). Washington University Record. Book 907. http://digitalcommons.wustl.edu/record/907

This Article is brought to you for free and open access by the Washington University Publications at Digital Commons@Becker. It has been accepted for inclusion in Washington University Record by an authorized administrator of Digital Commons@Becker. For more information, please contact [email protected]. Inside: John M. Olin Foundation Inc. gift Medical News: Cancers appear in Washington People: Gautam N. Yadama establishes new distinguished professorship mice treated with adeno-associated virus has an interdisciplinary approach 8

Sept. 14, 2001 Volume 26 No. 4 ^fchington University in St Louis PET proves best for revealing spread of cervical cancer

BY DARRELL E. WARD cancer. But CT scans are only moderately accurate. They often Physicians at the School of suggest that a cervical tumor has Medicine and the Alvin J. not spread to lymph nodes when Siteman Cancer Center of the in fact it has. medical school and Barnes-Jewish Grigsby, along with colleagues Hospital have found evidence that Barry A. Siegel, M.D., and Farrokh positron emission tomography Dehdashti, M.D., of the Division (PET) is more accurate than the of Nuclear Medicine, compared current standard, computed CT scans with PET scans in 101 tomography (CT), in determining women with cervical tumors whether cervical cancer has detected during a physical spread to other areas of the body. examination. Their results were published in They took the Sept. 1 issue of the Journal of images of the Clinical Oncology. cervical tumor "Our study shows that PET is itself (the the most accurate imaging method primary presently available for identifying tumor) and of secondary tumors in patients with lymph nodes Hundreds of students gathered in Brookings Quadrangle Tuesday night for a community gathering and cervical cancer," said Perry Grigsby, in three areas candlelight vigil to remember those hurt or killed in the day's terrorist attacks. M.D., professor of radiation of the body: oncology at the medical school's the pelvis, the Mallinckrodt Institute of Radiol- Grigsby abdomen World Trade Center, Pentagon attacks ogy and first author of the study. around the Knowing whether a tumor has aorta (para-aortic lymph nodes) spread to the lymph nodes is and the base of the neck above the Tragedies could bring lasting impact essential for determining the most collar bone (supraclavicular appropriate treatment for a lymph nodes). These areas follow BY NEIL SCHOENHERR patient. Tumors confined to the the path taken by cervical cancer Wrighton: 'Uphold the utmost respect' wall of the uterus are treated by as it advances. Disasters caused by human surgically removing the uterus PET scans confirmed the action tend to create more Chancellor Mark S. Wrighton cities," Wrighton said. and the woman has a 90 percent presence of a cervical tumor in mental health problems said the University is doing In light of the tragedy and chance of being cancer-free five 100 of the 101 women, while CT than "acts of God" such as all it can to help students out of respect to the affected years later. Once the tumor has scans identified only 77. In the earthquakes or tornadoes. And effectively deal with Tuesday's members in the community, spread, however, radiation lymph nodes, PET revealed among disasters caused by human tragedy. classes were canceled from therapy without surgery is abnormal pelvic nodes in 67 of the action, terrorist attacks tend to be "Our sympathies go out to noon-10 p.m. Tuesday. administered and the odds of women, while CT found 20; PET the most severe, said Carol S. those affected by these attacks, "We must continue to survival drop to 45 percent. revealed abnormal abdominal North, M.D., professor of and to those members of the uphold the utmost respect for At present, physicians use CT nodes in 21 women, whereas CT psychiatry at the School of University community who the diverse people who consti- to assess the extent of cervical See PET, Page 6 Medicine. share our great concern for the tute the Washington University "This ranks in the disaster safety and well-being of their community," Wrighton said. typology as perhaps the most family, friends and classmates "People from all areas of the Wooley receives Cope scholar award severe kind in evoking psychiatric who live and work in these See Community, Page 6 and psychological responses," BY TONY FITZPATRICK University. North said. "Probably the most The award important thing to realize is that "The world watched this on Karen L. Wooley, Ph.D., consists of the majority of people will have On Page 6 television," Le Vine said. "The professor of chemistry in Arts $5,000, a some kind of emotional response, effect is going to be worldwide & Sciences, has been awarded the certificate and ' Blood donation information and the closer they are to the with some traumatic effects, given 2002 Arthur C. Cope Young a $40,000 impact, the greater that response > Speeches made at Tuesday's vigil the central location of New York Scholar Award, sponsored by the unrestricted will be." and Washington, D.C., to world American Chemical Society (ACS). research grant North, along with Victor T. trade and world operations." The annual awards, this year to be assigned Le Vine, Ph.D., professor of impact may experience some But Le Vine warned against given to two chemists age 35 or by the political science in Arts & symptoms of emotional distress. too much speculation surround- younger before April 30, 2002, are Wooley recipient to Sciences, and Chancellor Mark However, this does not mean that ing the events. highly prestigious accomplish- any university S. Wrighton spoke at a news all people will develop a psychiat- "This was a coordinated attack ments in the field of organic or nonprofit institution. Wooley is conference Tuesday morning in ric disease; the one that occurs on targets in New York and chemistry. They are given to required to deliver a lecture at the the Alumni House. most commonly in such instances Washington, D.C.," he said. recognize and encourage excel- annual Arthur C. Cope Sympo- North has studied similar is post-traumatic stress disorder. "However, I do think that lence in organic chemistry. sium to be held as part of the disasters internationally and in Le Vine has written, researched excessive speculation about who This year's other Cope Young ACS's annual meeting in August the . She said the and taught on the subject of is behind the attacks is unwar- Scholar Award went to Matthew 2002 in Boston. majority of people close to the terrorism for the past 25 years. See Tragedies, Page 6 D. Shair, Ph.D., of Harvard See Award, Page 5

Superexchange in molecular electronic switch broadens possibilities

BY TONY FITZPATRICK ted from one molecule to another of the various processes involved until the final output molecule and found that the key to the Using photosynthesis as their emits light. To make a molecular operation is efficient communica- model, chemists at Washing- optoelectronic switch, a unique tion between molecules that are ton University, North Carolina molecular component is attached distant from one another in the State University and the Univer- and, when activated, accepts and device. sity of California, Pdverside, have dissipates the energy, turning off Such a process is known as tested molecular electronic the light emission. superexchange and has been switches that turn the flow of light To the surprise of the chemists, known for some time in charge energy on and off. a T-shaped arrangement in which transfer, but its role in excited- Taking molecules called the switching molecule is located state energy transfer is less well- porphyrins that are related to the perpendicular to one of the studied. green chlorophyll pigments of transmission molecules in the Dewey Holten, Ph.D., profes- photosynthesis, the chemists have wire works just as effectively as a sor of chemistry in Arts & studied many different arrays, or linear arrangement where the Sciences, and doctoral candidate alignments of molecules. In switch molecule is attached Robin Lammi removed an Dewey Holten, Ph.D., professor of chemistry in Arts & Sciences, molecular electronic wires, light directly to the output component. electron from the switch mol- adjusts lenses in his sophisticated Louderman Hall laser laboratory. energy absorbed by an input The Washington University ecule, a magnesium porphyrin, Using photosynthesis as their model, Holten and his collaborators molecule at one end is transmit- chemists characterized the speeds See Switch, Page 7 are testing molecular electronic switches. 2 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS

U.S. News and World Report Undergraduate programs tied for 14th in latest national rankings Washington University — undergraduate business pro- consistently ranked among grams, including Emory America's 20 best national University, Penn State University universities — is now tied with and the University of Maryland. Cornell University for 14th "It is gratifying to see place in undergraduate recognition coming to Washing- programs, according to U.S. ton University," Chancellor Mark News and World Report S. Wrighton said. "Our success is magazine. due to the excellent students, Washington University faculty and staff who bring great climbed one notch from last value to the educational year's tie for 15th among the environment here. We have been 249 national universities rated generously supported by our by U.S. News. The tie for 14th is alumni, friends, corporations, the best undergraduate ranking and foundations in our efforts to of the University by U.S. News create the best programs for since the publication began its education and scholarship. rankings in the 1980s. Continued program develop- The U.S. News undergradu- ment and support will enhance ate rankings are derived from our impact and value to society." data gathered from each In March, U.S. News published institution, and this data is its annual rankings of graduate and broken down into categories professional programs, placing the and assigned a George Warren Learning Opportunity (Left-right) Robert Wiltenburg, Ph.D., dean of University College and weight reflecting _ -™- Brown School of assistant dean of Arts & Sciences; Chancellor Mark S. Wrighton; Richard A. Roloff, executive vice the magazine's Social Work at chancellor; Richard Diemer, director of the Lifelong Learning Institute (LLI) of University College; judgment about "Our success is due to No. 2 in the Edward S. Macias, Ph.D., executive vice chancellor and dean of Arts & Sciences; and Lawrence which measures nation and the Kahn, M.D., professor emeritus of pediatrics at the School of Medicine, congratulate Henrietta of quality matter the excellent students, School of Freedman, founder of LLI and a former University trustee, after she cut the ribbon to open the new most. This year's faculty and staff who Medicine No. 4. home of the LLI. The institute hosted its first Fall Address and Open House Sept. 7. LLI, now located results, published Ten programs at 9 N. Jackson Ave., offers a variety of study groups based on cooperative learning and member in the U.S. News bring great value to the within the involvement to seniors in the community. issue dated Sept. educational environment School of 17, rank the Medicine ranked University as fifth here Continued in the top 10 in in financial program development the nation, Distinguished professorship resources, 12th in including faculty resources and support will enhance p^^erapy and 12th in our impact and value to at No. l and Olin foundation gift honors new faculty member alumni giving. . » occupational The University SOCiety. therapy at No. 3. BY BARBARA REA resources for the school's rapid development, economic growth tied for eighth in MARK S. WRIGHTON The microbiol- ascension to the top tier of and fluctuations, industry percentage (71 ogy program A distinguished professorship business schools. dynamics and industrial organi- percent) of ranked fourth, established in the John M. In addition, the Olin zation." classes with less than 20 and internal medicine was fifth. Olin School of Business will foundation helped establish the MacDonald comes to the students. Altogether, more than 30 honor new faculty member University's Murray University from the University of The U.S. News "Best Value" undergraduate and graduate Glenn MacDonald, Chancellor Weidenbaum Center on the Rochester, where he was a category ranks schools that programs and schools at the Mark S. Wrighton announced. Economy, Government, and professor of economics and offer a high-quality education University are ranked by U.S. The $2 million gift from the Public Policy and the Center for management at the WE. Simon at an affordable cost, including News and World Report as being John M. Olin Foundation Inc. the History of Freedom. School of Business. financial aid. The University in the top 25 of their respective endows the John M. The foundation was His work has appeared in tied for 16th with Duke areas. Olin Distinguished created by John M. Olin many publications, including the University and Case Western The magazine and an Professorship in in 1953. Olin, a leading Journal of Political Economy, the Reserve University. Last year, undergraduate guidebook are Business, Law and industrialist and American Economic Review, the University was tied for 17th. available at newsstands. All Economics. The formal philanthropist, also Econometrica and the Journal of The Olin School of Business rankings also are available on the installation for provided funds for the the American Statistical Associa- once again was tied for 16th magazine's Web site, MacDonald will be later University's main tion. His research and applica- with seven well-known www.usnews.com. in the school year. library on the Hilltop tions of game theory have been "Bestowing this Campus. used at many corporations, Faculty Achievement Awards Ceremony Wednesday wonderful gift deepens Olin School Dean including Bausch & Lomb, Chase the already strong Stuart I. Greenbaum, Manhattan Bank, Eastman Kodak The University community is professor of anatomy and legacy of support from MacDonald: New Ph.D., noted that the Co., IBM, Xerox Corp. and 1 invited to attend the third neurobiology at the School of Olin professor the John M. Olin endowment of a General Motors Corp. annual Faculty Achievement Medicine, will talk at the Foundation to Washing- professorship in the MacDonald earned a Awards Ceremony at 4:30 p.m. ceremony on "Going for the ton University," Wrighton said. school bearing the foundation's bachelor's degree in economics Wednesday at the Eric P. Genes." Arvidson, the James S. "We are immensely grateful for name is not only a great match, and mathematics from York Newman Education Center, McDonnell Distinguished the foundation's exceptional gift, but also a critical move that will University and master's and 320 S. Euclid Ave. University Professor and chair as well as for all the support it bring greater distinction as one doctoral degrees in economics This year's honorees are of the Department of Earth has given us through the years." of the top business schools in from the University of Rochester. Robert H. Waterston, M.D., and Planetary Sciences in Arts The John M. Olin Founda- the country. "Glenn MacDonald leads an Ph.D., winner of the Carl and & Sciences, will speak on tion supports a number of "We are most fortunate to all-star cast of 15 new faculty Gerty Cori Award for Faculty "Mars: Ancient Climates and academic endeavors at the have attracted Glenn joining Olin this year," Achievement, and Raymond E. the Search for Life." University and has been MacDonald, a pre-eminent Greenbaum said. "Joining Olin's Arvidson, Ph.D., winner of the Waterston and Arvidson especially generous to the economist," Greenbaum said. star-studded current faculty, they Arthur Holly Compton Award will receive $5,000 honorari- business school. In recognition "Glenn brings to the Olin will propel the Olin School to for Faculty Achievement. ums and framed citations. A of a $15 million challenge grant School intellectual leadership in new heights of excellence and Waterston, the James S. reception will immediately made by the foundation in 1987, a range of areas, including game recognition." McDonnell Professor and head follow the ceremony. the school was named the John theory, business strategy, The Olin Foundation gift is of the Department of Genetics, Reservations are not M. Olin School of Business. The technological change, labor part of the Campaign for director of the Genome required. For more informa- foundation helped provide the economics, research and Washington University. Sequencing Center and tion, call 935-5211. Zabin to discuss reproductive health issues Record (USPS 600-430; ISSN 1043-0520), Laurie S. Zabin, Ph.D., director School of Hygiene and Public in Johns Hopkins' Department of Volume 26, Number 4/Sept. 14,2001. of the Bill and Melinda Gates Health, Zabin works with develop- Population & Family Health Published for the faculty, staff and friends Institute for Population and ing countries around the world, Sciences and the Department of Washington University community news of Washington University. Produced weekly Reproductive Health, will discuss helping them create their own Gynecology and Obstetrics in the Editor Kevin M. Kiley during the school year, except school "Lessons From U.S. Involvement in reproductive health programs. university's medical school, Assistant Editor Jessica N. Roberts holidays, and monthly during June, July and August by the Office of Public Affairs, International Reproductive and "The institute is developed on entered the family planning field Assistant Editor Neil Schoenherr Associate Vice Chancellor Judith Jasper Leicht Washington University, Campus Box 1070, Sexual Health Debates" at 4 p.m. the principle that the time is over as a Planned Parenthood volun- Executive Editor Susan Killenberg McGinn One Brookings Drive, St. Louis, M0 63130. Wednesday in the Women's when we should ship programs teer in the 1950s. Since then, she Medical News Editor Anne Enright Shepherd Periodicals postage paid at St. Louis, M0. Building formal lounge. out of America and Europe," has received numerous awards Production Carl Jacobs Where to send address changes, News & Comments A reception with Zabin will be Zabin told the 2000 Vassar and held many posts, including corrections: held at 3:30 p.m. in the lounge. Alumnae/i Quarterly. "Our serving on the adolescent health (314)935-6603 International and Area Studies, the mission is to develop the capacity, committee of the American Campus Box 1070 Postmaster and non-employees Record, [email protected] Washington University, Campus Box 1070, Medical Anthropology Program of both on the individual and the College of Obstetrics/Gynecology, Medical News One Brookings Drive, St. Louis, MO 63130. the Department of Anthropology, institutional level, for the develop- the National Institutes of Health (314)286-0119 Employees Office of Human Resources, and Women's Studies, all in Arts & ing world to handle their own Panel on Long-Acting Contracep- Campus Box 8508 Washington University, Campus Box 1184, Sciences, are co-sponsoring her programs. You can't create tion, and the White House [email protected] One Brookings Drive, St. Louis, M0 63130. talk and reception. Both are free anything as appropriate to a Initiative on Adolescent Preg- and open to the public. culture as what they create for nancy Prevention. As director of the institute, themselves." For more information, call I VfehingtonUniversity in St IDIUS which is at the Johns Hopkins Zabin, who is also a professor 935-5073. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Sept. 14, 2001 3 Medical School Update Cancers appear in mice treated with adeno-associated virus Studying one type of gene compartments that dismantle cancer. Moreover, the research- cause cancer in mice if the vector discovered, University investiga- therapy in mice, researchers complex molecules into constitu- ers have never seen these tumors is injected intravenously; tors informed the U.S. Food and made an unexpected and ent pieces. When one of their in the many mice they have • Overexpression of the human Drug Administration and the unsettling discovery: Six animals enzymes is missing, the large treated in other ways for beta- beta-glucuronidase gene in mice National Institutes of Health eventually developed cancer. molecules pile up, damaging cells glucuronidase deficiency. may cause cancer, regardless of (NIH) of their findings. The The results of the National in many tissues. The University study was not the vector; research was discussed in a Institutes of Health-funded study In these mice, just one injection designed to determine whether • Gene therapy with AAV may public meeting sponsored by are described in two scientific of the gene-carrying virus raised AAV might be linked to cancer. cause cancer in mice; NIH's Recombinant DNA reports published in the current production of beta-glucuronidase It set out to test the long-term • The disease mucopolysacch- Activity Committee March 7 in issue of the journal Gene Therapy. enzyme to functional levels for at efficacy of gene therapy for mice aridosis type VII (MPS VII) may Rockville, Md. The research team, headed by least a year. The treated mice lacking beta-glucuronidase. predispose these animals to Humans who lack beta- Mark S. Sands, Ph.D., assistant gained near-normal amounts of Possible explanations for the malignancies. glucuronidase have Sly's syndrome professor of medicine and of weight, their bones grew to almost findings include: Further studies will be needed (also called beta-glucuronidase genetics at the School of Medi- normal lengths, and they didn't • Gene therapy with the to distinguish among these deficiency or MPS VII). They are cine, used adeno-associated virus develop retinal problems. There- particular recombinant AAV possibilities, the researchers stress. unable to break down certain large (AAV) to insert a human gene fore, gene therapy just after birth used by Sands' group may cause Sands' group is repeating the carbohydrates (dermatan sulfate, into 59 newborn mice. The gene prevented many of the symptoms cancer in mice; experiment to determine if the heparan sulfate and chondroitin coded for the enzyme beta- associated with lysosomal storage • Gene therapy with AAV may results are reproducible. sufates) and can have short glucuronidase, which the mice disease. cause cancer in mice if per- The agent used for gene stature, mental retardation, were unable to produce because When the surviving mice were formed during the neonatal transfer in these experiments, abnormal facial features and their own beta-glucuronidase checked at 18 months old, three of period; AAV, has been used in human numerous other problems. genes were mutated. Their the five had signs of liver cancer. • Gene therapy with AAV may gene-therapy trials. However, No patient with Sly's syndrome condition mimicked Sly's Examination of additional mice cause cancer in mice that lack those human trials employed a or other lysosomal storage disease syndrome, one of more than 40 that were either sacrificed or beta-glucuronidase because localized method of delivery, has undergone gene therapy with lysosomal storage diseases that in spontaneously died between 8 and these mice are immunocom- rather than the systemic, intrave- AAV. The clinical trials involving aggregate affect approximately 1 18 months identified three more promised and have other organ nous approach used in this special AAV have focused on other in 5,000 babies. animals with tumors. None of problems; mouse model. diseases, such as cystic fibrosis and Lysosomes are cellular eight surviving untreated mice had • Gene therapy with AAV may At the time the tumors were hemophilia. Study examines how human genes influence medications

BY DARRELL E. WARD that person," McLeod said. The present project focuses on Scientists at the School of human gastrointestinal cancer, Medicine and the University which has ethnic differences both of Southern California (USC) are in incidence and in treatment collaborating on a major new outcome and is treated using three research effort to better under- drugs. The project aims to identify stand how a person's genes and evaluate variations in 95 genes influence the effectiveness of involved in the action of the three medicines he or she takes. drugs. Doctors know that small Developing strategies to genetic differences can affect individualize medicine requires whether drugs will work in that the study be comprehensive. It particular patients, but until includes, for example, some recently researchers have been scientists doing genetic analysis able to study the differences in and others studying how minor only one or two ^__^^_ __mmmm changes in genes genes at a time. influence a "Now, we are "Our overall goal is to protein's structure going beyond and function. that," said understand how and Statistical Howard L. why people can have geneticists are McLeod, developing ways Pharm.D., such differing responses to assess how principal to a wide array of changes in several investigator for genes are impor- It S a ZOO OUt there (From left) Brian DeBosch and Jacob Nadler get to know William A. Peck, the project and medicines." tant for individual M.O., executive vice chancellor for medical affairs and dean of the School of Medicine, at a welcom- associate ROCHELLE LONG patients, and ing party Friday at the St. Louis Zoo's River Camp. Peck hosted the party to kick off the academic professor of clinical specialists year for the 120 first-year medical students. medicine, of integrate the molecular biology and pharma- genetic information into the cology and of genetics at the treatment of patients. medical school. "We are studying The study, which relies heavily Francis Collins to speak at Danforth Symposium Thursday entire gene pathways that appear on the findings and technology of to be important for a given the Human Genome Project, This year's William H. Danforth Project for Medicine and Society." Ph.D., associate professor of medication." focuses on cancer, McLeod said, SScientific Symposium He oversees the public effort to genetics and assistant investigator The project is funded through "but the strategies we are develop- "Medicine at the Millennium" on map and sequence the human at Howard Hughes Medical a four-year, $6.6 million grant ing will be applicable to many Thursday will focus on the genome and is widely known for Institute, will talk about "Com- from the National Institute of diseases." University's role in understanding his contributions to human parative Genomics: Trying to General Medical Sciences McLeod and Lenz's program is the human genome. genetics. His research led to the Understand the Human Ge- (NIGMS). It represents an part of a National Institutes of . Francis Collins, M.D., Ph.D., identification of genes responsible nome," and Alan Templeton, emerging area of medicine known Health (NIH) initiative known as director of the National Institute for cystic fibrosis, neurofibroma- Ph.D., the Charles Rebstock as pharmacogenetics. the Pharmacogenetics Research of Human Genome Research at tosis and Huntington's disease. Professor of Biology in Arts & "This is a very exciting Network. "NIH assembled the the National Institutes of Health, Other University speakers Sciences, will address "Going opportunity," said Heinz-Josef network to bring together pharma- will give the keynote address. include Robert H. Waterston, Beyond the Genome: Lessons Lenz, M.D., associate professor of cogenetics scientists across The free symposium will begin M.D., Ph.D., the James S. from Genetic Studies on Coro- medicine at USC's Keck School of different disciplines and disease at 1 p.m. in the Eric P. Newman McDonnell Professor and head of nary Artery Disease." Medicine and that site's lead areas," said Rochelle Long, a Education Center at 320 S. Euclid the Department of Genetics, who Chancellor Mark S. Wrighton investigator. "The goal of our pharmacologist at NIGMS who Ave. The half-day event is will speak on "The Human and William A. Peck, M.D., laboratory is to establish a strong spearheaded the pharmacogenetics designed for faculty, graduate Genome Project: Where Have We executive vice chancellor for translational research program initiative. "Our overall goal is to students and fellows, but the Come From? Where are We medical affairs and dean of the that uses molecular markers to understand how and why people entire University community is Going?" and Anne Bowcock, medical school, will address the tailor chemotherapy for each can have such differing responses welcome to attend. Ph.D., professor of genetics, who symposium as well. patient. This grant is making our to a wide array of medicines.' Collins will speak on "Conse- will discuss "Finding Genes for The symposium was estab- collaboration the cutting-edge quences of the Human Genome Complex Diseases." Sean Eddy, lished to recognize Danforth's instrument for pharmacogenetic longtime contribution to the research in the world." University and the School of Lenz is also a research Yokoyama receives Novartis award for basic immunology Medicine. Danforth, who began a oncologist with USC/Norris medical residency at Barnes Comprehensive Cancer Center. Wayne M. Yokoyama, M.D., of Research in Arthritis and a are awarded for outstanding Hospital in 1954, served as vice McLeod, an investigator with was awarded Novartis' 2001 professor of pathology and achievements in understanding the chancellor for medical affairs and the Alvin J. Siteman Cancer Prize for Basic Immunology at the immunology at the School of body's immune system and major as president of the Washington Center of the University and 1 lth International Congress for Medicine. He also is an investigator immunological discoveries that lead University Medical Center from Barnes-Jewish Hospital, and his Immunology in Stockholm, for the Howard Hughes Medical to therapeutic applications. 1965-71. He was chancellor of the colleagues will focus mainly on Sweden. He was recognized for his Institute and chief of the rheuma- Yokoyama shared the award University from 1971 until his "individualized medicine," how to groundbreaking scientific contri- tology division at the medical with Klas Karre from Stockholm, retirement in 1995. He now identify the best choice of butions to our understanding of school and Barnes-Jewish Hospital. Sweden, and Lorenzo Moretta of serves as vice chairman of the medication for each patient. natural killer cells and the molecu- The Novartis prizes for immu- Genoa, Italy, in honor of their work Board of Trustees and chancellor "We will use knowledge of a lar basis for their function. nology are presented every three on natural killer cells. These emeritus. drug's action in the design of DNA Yokoyama is the Sam J. Levin years and are renowned as the most components of the body's immune For more information about tests to predict a drug's effect on and Audrey Loew Levin Professor prestigious awards in the field. They system fight tumors and infections. the symposium, call 286-0071. 4 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS University Events Poet, fiction writer Howe to read for The Writing Program Reading Series

BY LIAM OTTEN take place in American Writing Award, dark Best American Poetry of 2000; the Hurst Lounge, forces intermingle with a rich Commonwealth of California Fanny Howe, author of more located in sense of wonder. Gold Medal Award for Poetry, than 20 books of poetry and Duncker Hall "In both her fiction and her 2001; the Pushcart Prize for fiction, will read from her Room 20 LA poetry, Fanny Howe shows how Fiction; an American Book Award work at 8 p.m. Thursday for The book signing language itself can be used as the for Fiction; a National Poetry Writing Program Reading Series. will follow the medium of pilgrimage, of Foundation Award; and two Howe is in residence for two reading, and What: Colloquium on the craft of poetry spiritual inquiry," said Carl awards from the National Endow- weeks in The Writing Program in copies of Phillips, professor of English and ment for the Arts. the Department of English in Howe's works When: 8 p.m. Sept. 27 director of The Writing Program. Other books of poetry include Arts & Sciences, serving as Fannie will be available "The result is the return of faith "The End" (1992), "One Crossed Hurst Professor of Creative for purchase. been called "meditations on in language and in the capacity Out" (1997) and "The Vineyard" Literature. Howe's most recent book of matter and spirit, on the won- for language still to save us." (1988). Her most recent novel, In addition, Howe will lead a poetry, "Selected Poems"(2000), drous strangeness of human life Howe is currently professor of "Indivisible," was published colloquium on the craft of poetry contains 16 series of lyrics on earth." writing and American literature this year. at 8 p.m. Sept. 27. Both events are gathered from her work over the In her novels too, such as at the University of California, For more information, call free and open to the public and past 20 years. The poems have "Nod"(1998), which won a New San Diego. Her awards include 935-7130.

Throwing Light • The Other Helsinki • Goodpasture Syndrome

"University Events" lists a portion of the 4 p.m. Chemistry-biology interface Pierce, prof, emeritus of medicine. East Tuesday, Sept. 25 (Also 8:30 p.m. vs. U. of Puget Sound, activities taking place at Washington seminar. "How Are Peptide Antibiotics Pavilion Aud., Barnes-Jewish Hosp. Bldg. Tacoma, Wash.) Field House. 935-5220. University Sept. 14-26. Visit the Web for Macrocyclized Enzymatically?" 362-6904. Noon. Mathematics analysis seminar. 7 p.m. Women's soccer vs. Carleton expanded calendars for the School of Christopher Walsh, prof., Harvard Medical 1 p.m. Genetics seminar. Danforth "Estimates on the Dimension of the College, Northfield, Mich. Francis Field. Medicine (medschool. wustl. edu/events/) School. Room 458 Louderman Hall. symposium. "The Human Genome Symmetry Group of a System of 935-5220. and the Hilltop Campus cfBOOO. wustl.edu/ 935-4665. Project: Revolutionizing Medicine and Partial Differential Equations." Herve calendar/events/). 4 p.m. Condensed matter/materials and Science." Eric P. Newman Education Gaussier, U. of Provence, Marseille, France. Room 199 Cupples I Hall. Saturday, Sept. 15 biological physics seminar. "Growth Center. 362-2062. Morphology of Epitaxial Rare Earth Thin 935-6760. 10 a.m. Volleyball WU National Invitational 4:30 p.m. Mathematics colloquium. Films and the Interplay Between Structure vs. Ohio Northern U., Ada. (Also 3 p.m. vs. "Models in Moebius Differential Noon. Molecular Microbiology and and Magnetism." Katharina Theis-Brbhl, U. of Wisconsin, Whitewater.) Field House. Geometry." Udo Hertrich-Jeromin, Microbial Pathogenesis Seminar Inst. of Experimental Physics/Solid State 935-5220. Exhibitions Technical U. in Berlin. Room 199 Cupples series. "Diabetic Yeast: Glucose Physics, Ruhr-U. of Bochum, Germany. I Hall (tea 4 p.m., Room 200). 935-6760. Sensing by a Simple Eukaryotic Cell." Room 241 Compton Hall (coffee 3:45 H. Mark Johnston, prof, of genetics. "Al Parker: Innovator in American Sunday, Sept. 16 p.m.). 935-6276. 6:15 p.m. Germanic Languages and Cori Aud., 4565 McKinley Ave. Illustration" Through Oct. 5. WU Special Literatures lecture. "The Nature of Evil: 362-3692. 3 p.m. Women's soccer vs. Fontbonne 7 p.m. Architecture Monday Night Lecture Collections, fifth floor, Olin Library. From the Simple to the Complex." John A. College. Francis Field. 935-5220. Series. "The Other Helsinki - The Reverse 935-5495. McCarthy, prof, of German and of Face of Architecture in the City." Juha Wednesday, Sept. 26 comparative literature, Vanderbilt U., . "Thomas B. Allen, Innovator of American llonen, visiting assoc. prof., Helsinki, Wednesday, Sept. 19 Nashville, Tenn. 935-4360. 8 a.m. Obstetrics and Gynecology Illustration: A Retrospective." Through Finland. Steinberg Hall Aud. (reception Sept. 16. Des Lee Gallery, University Lofts Grand Rounds. "BV-HIV Connection." 7 p.m. Volleyball vs. Fontbonne College. 6:30 p.m., Givens Hall). 935-6293. Bldg., 1627 Washington Ave. 621-8735. Friday, Sept. 21 Sharon Hillier, prof, of obstetrics and Fontbonne College, St. Louis. 935-5220. gynecology, Magee-Women's Hosp., Tuesday, Sept. 18 9:15 a.m. Pediatric Grand Rounds. "The U. of Pittsburgh School of Medicine. Thursday, Sept. 20 History of Pediatric Heart and Lung Noon. Mathematics major oral/analysis Clopton Aud., 4950 Children's Place. Transplantation." Eric N. Mendeloff, assoc. 4 p.m. Women's tennis vs. Quincy U. Tao seminar. "Sobolev Mappings With 362-1016. prof, of surgery, cardiothoracic surgery tennis Center. 935-5220. Integrable Dilatation." Leonid Kovalev. Lectures div.; and assoc. surgical dir., pediatric 11 a.m. Assembly Series. Coral Courts Room 199 Cupples I Hall. 935-6760. heart and lung transplantation, St. Louis lecture. Maya Lin, artist, sculptor and designer, will present her work. Co- Saturday, Sept. 22 Noon. Molecular Microbiology and Children's Hosp. Clopton Aud., 4950 Friday, Sept. 14 Microbial Pathogenesis Seminar series. Children's Place. 454-6006. sponsored by School of Architecture. Noon. Volleyball UAA Round Robin vs. U. of "The Role of Lipids and Lipid Secretion in Graham Chapel. 935-5285. Chicago. Field House. 935-5220 9:15 a.m. Pediatric Grand Rounds. Noon. Cell biology and physiology the Pathogenesis of Mycobacterium 1:15 p.m. Ethical conduct of research 1 p.m. Football vs. Albion College, Mich. "Mechanisms of Cell Death Following seminar. "Ubiquitin-mediated Proteolysis tuberculosis." Clifton E. Barry, chief, seminar (School of Medicine). Co- Francis Field. 935-5220. Neonatal Hypoxic-ischemic Brain Injury." as a Key Regulator of Biological Tuberculosis Research Section, NIH. Cori sponsored by psychiatry dept. and David M. Holtzman, the Charlotte and Processes." Dorata Skowyra, asst. prof, of Aud., 4565 McKinley Ave. 362-8873. Comorbidity and Addictions Center. Paul Hagemann Assoc. Prof, of biochemistry and molecular biology, Saint Sunday, Sept. 23 East Pavilion Aud., Barnes-Jewish Neurology and assoc. prof, of molecular 4 p.m. Anesthesioiogy research seminar. Louis U. School of Medicine. Room 426 Hosp. Bldg. 286-2252. 10 a.m. Volleyball UAA Round Robin vs. U. biology and pharmacology, Center for the Eileen Lafer, assoc. prof, of biochemistry McDonnell Medical Science Bldg. of Rochester, N.Y. Field House. 935-5220. Study of Nervous System Injury. Clopton and dir., UTHSCSA Surface Plasmon 747-4233. 5:15 p.m. Mothers and Babies Resonance Lab., U. of Texas Health 2 p.m. Volleyball UAA Round Robin vs. Aud., 4950 Children's Place. 454-6006. 4 p.m. Geometry seminar. "Holly's Tori and Research Center conference. "How Science Center, San Antonio. Room 5550 Placentas Get Fat." W. Timothy Case Western Reserve U., Cleveland. Field Noon. Cell biology and physiology Co." Udo Hertrich-Jeromin, Technical U. in Clinical Sciences Research Bldg. Schaiff, research instr. in obstetrics House. 935-5220. seminar. "Signal Transduction Berlin. Room 199 Cupples I Hall. 362-8560. and gynecology and interdisciplinary Mechanisms Guiding Cell Migration in the 935-6760. women's health research scholar. Nervous System." Yi Rao, assoc. prof, of Tuesday, Sept. 25 7:30 p.m. St. Louis Astronomical Society Room 36, third floor south, St. Louis anatomy and neurobiology. Room 426 Wednesday, Sept. 19 lecture. "Beginner's Guide to Mars and Children's Hosp. 747-0739. 7 p.m. Women's soccer vs. Maryville U. McDonnell Medical Sciences Bldg. 362- 8 a.m. Obstetrics and Gynecology Grand the Stars." Introduction to star-gazing by Francis Field. 935-5220. 6950. Rounds. "History of the 0B/GYN members of the Saint Louis Astronomical 7:30 p.m. School of Art Visiting Artist Lecture Series. Zoe Beloff, City 4 p.m. Anatomy and neurobiology Department of Washington University." Society. Co-sponsored by earth and College and N.Y.U. Steinberg Hall Aud. seminar. "Throwing Light on Synaptic Yasmine Kareem, chief resident, obstetrics planetary sciences and NASA's 935-6500. Plasticity in New Ways." Jeffery W. and gynecology dept. Clopton Aud., 4950 Space Grant Consortium. Room 162 Lichtman, prof, of anatomy and Children's Place. 362-1016. McDonnell Hall. 935-4614. And more... neurobiology. Room 928, McDonnell 11 a.m. Assembly Series. Robert Frank, Medical Sciences Bldg. 362-7043. author and prof, of economics, Cornell U. Saturday, Sept. 22 Co-sponsored by the economics dept. 4 p.m. Foreign Language Learning 1 p.m. Joint Center for East Asian Studies Saturday, Sept. 15 Colloquium Series. "Gender and Graham Chapel. 935-5285. Music symposium. "East Asian Studies and the Interaction in the Language Classroom." 4 p.m. Medical Anthropology, Interna- Popular Imagination." Kyoko Mori, 9 a.m. Professional development Monika Chavez, assoc. prof, of German tional and Area Studies, and Women's novelist, and Chang Chen-yi, animator workshop. "Building Your First Web Page." and applied linguistics, U. of Wis., Studies. "Lessons From U.S. Involvement (Disney's "Mulan"). Women's Bldg. Friday, Sept. 14 Rob Compton, manager, Arts & Sciences Madison. Co-sponsored by The Teaching Computing Center. Cost: $30. Room 14 in International Reproductive and Sexual Lounge. 935-4448. 8 p.m. Acoustic City Concert Series. Center and the dean of the faculty of Arts Eads Hall. To register, call 935-6759. Health Debates." Laurie Zabin, dir. of Bill Eddie from Ohio, which Sing Out! and Sciences. Room 162 McDonnell Hall. and Melinda Gates Inst. for Population and Magazine calls "contemporary folk- 935-5175. Monday, Sept. 24 Reproductive Health, Johns Hopkins U. on-steroids." Cost: $12 in advance, Tuesday, Sept. 18 Women's Bldg. Lounge (reception 3:30 Noon. Neurology and neurological surgery 4 p.m. Mathematics colloquium. "Spectral $14 at the door (free for Washington Noon-1 p.m. Toastmasters event. Gaps of Periodic Schroedinger Operator p.m.). 935-5073. research seminar. "Molecular U. students, staff and faculty). The Mechanisms of Early and Delayed Cell Sponsored by Washington U. Toastmasters and Smoothness of Its Potential." Steven 5 p.m. Ophthalmology and Visual Sciences Gargoyle. 935-7576. Death Following Neonatal Hypoxia- for Oratorical Readiness (WUTF0R). Room G. Krantz, prof, and chair of mathematics. Grand Rounds. "Glacomatous Optic Nerve ischemic Brain Injury." David M. 1140A, 4480 Clayton Ave. 286-0133. Room 113 Cupples I Hall (tea 3:30 p.m., Damage With Visual Field Loss Increases Holtzman, the Charlotte and Paul Sunday, Sept. 16 Room 200). 935-6760 the Risk of Falls and Non-spine Fractures." Hagemann Prof, of Neurology, and assoc. Thursday, Sept. 20 Anne Coleman, assoc. prof, of ophthal- 3 p.m. Music dept. faculty recital. prof, of molecular biology and pharmacol- mology, UCLA School of Medicine. "The "Music of the German Baroque: Bach 8 p.m. Writing Program Reading Series. Monday, Sept. 17 ogy. Schwarz Aud., first floor, Maternity Functional Vision Issues of Community and Before." Elizabeth Macdonald, Fanny Howe, poet and fiction writer, will Bldg. 362-7316. 10 a.m. Center for Mental Health Services Residing Older Adults." M. Carolyn Baum, viola da gamba; Charles Metz, read from her work. Hurst Lounge, Room Research seminar. "Research Agenda assoc. prof, and Elias Michael Dir. of Noon-1 p.m. Work, Families and Public harpsichord; and William Bauer, 201 Duncker Hall. 935-7130. for Racial Disparities in Mental Health program in occupational therapy; and Policy Brown Bag Seminar Series. violin. Steinberg Hall Aud. 935-4841. Services." Lionel Scott, research assoc, asst. prof, of neurology and neurological "Games Daughters and Parents Play: Monday, Sept. 24 Center for Mental Health Services surgery. East Pavilion Aud., Barnes- Teenage Childbearing, Parental Sunday, Sept. 23 Research. Room 38 Goldfarb Hall. Jewish Hosp. Bldg. 362-5722. Reputation, and Strategic Transfers." V. 7:30 a.m. STD laboratory methods course. 935-5687. Joseph Hotz, U. of Calif., Los Angeles. 3 p.m. WU Symphony Orchestra and Sponsored by St. Louis STD/HIV Jazz Band concert. Dan Presgrave, Noon. Molecular biology and pharmacol- Thursday, Sept. 20 Room 300 Eliot Hall. 935-4918. Prevention Training Center. (Continues symphony dir., Chris Becker, jazz band through Sept. 26.) Cost: $60. Room 601A ogy research seminar. "Building a 4 p.m. Committee on Comparative 8 a.m. Medical Grand Rounds. Saulo Klahr dir. Brookings Quadrangle (rain Becker Library. (Sept. 25,1 p.m., Second Brain: Enteric Neural Crest Literature lecture. "Woody Allen's lecture. "Goodpasture Syndrome Creeps location: Graham Chapel). 935-4841. Conference Room Storz Bldg.; and Sept. Development." Robert 0. Heukeroth, asst. Parodies." Seymour Chatman, prof, Into the Molecular Age." Eric G. Neilson, 26,7:30 a.m., Room 601A Becker Library.) prof, of pediatrics and of molecular emeritus of rhetoric and film, U. of Calif., the Hugh Jackson Morgan Prof., Registration required. 747-0294. biology and pharmacology. Room 3907 Berkeley. Room 110 January Hall. chairman, dept. of medicine, Vanderbilt U. South Bldg. 362-2725. 935-5170. Medical Center, Nashville, Tenn. Co- Wednesday, Sept. 26 Noon. Neurology and neurological surgery sponsored by the National Kidney 4 p.m. Immunology Research Seminar research seminar. "Role of apoE on A- Sports Foundation and Washington U. School of Series. "Current Ideas About Immuno- 7 p.m. Exploring the Universe Mini-series. Beta Metabolism: Insights From a Medicine. Clopton Aud., 4950 Children's logical Synapses." Andrey S. Shaw, prof, "A Warp-10 Tour of the Universe." Rich Transgenic Mouse Model of Alzheimer's Place. 454-7017. of pathology and immunology. Eric P. Heuermann, earth and planetary sciences Disease." Anne Fagan-Niven, research Newman Education Center. 362-2763. Friday, Sept. 14 dept. Co-sponsored by earth and planetary 11 a.m. Pulmonary and Critical Care asst. prof, of neurology. Schwarz Aud., sciences and NASA's Missouri Space Medicine Grand Rounds. "How It Really 4 p.m. Volleyball WU National first floor, Maternity Bldg. 362-7316. Grand Consortium. Room 162 McDonnell Happened: Pulmonary Medicine." John A. Invitational vs. U. of Wis., La Crosse. Hall. 935-4614. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Sept. 14, 2001 5 Parker symposium held today in Gallery of Art

BY LIAM OTTEN School of Art. Other participants include Terry Brown, director of A 1 Parker (1906-85), a 1928 the , New graduate of the School of Art, York; , illustra- was one of the most successful tor and professor at the School of and influential illustrators of the the Visual Arts, New York; and 1940s, '50s and '60s. His work for University alumnus Bernie Fuchs, Cosmopolitan, McCalls, Good the youngest artist ever elected to Housekeeping and other major the Society of Illustrators Hall of monthlies chronicled — and, it Fame. might be argued, helped shape — The afternoon session, "Al the fashions, attitudes and Parker & the Weekly Magazine: aspirations of post-war America. The Mid-Century Cultural The Visual Arts and Design Context," begins at 1:15 p.m. and Center will host an all-day is moderated by Angela Miller, symposium today in the Callery associate professor in the Depart- of Art in Steinberg Auditorium ment of Art History & Archaeol- about Parker's work and legacy. ogy in Arts 8c Sciences. Other The event, which is free and open participants include Alice Carter, to the public, comes in conjunc- professor in the School of Art and tion with the exhibition "Al Design at San Jose State Univer- Parker: Innovator in American sity; Christopher S. Clarke, an Illustration," now on display in independent exhibition developer the University's Special Collec- and consulting historian; and tions, located on the fifth level of Michael J. Murphy, a doctoral Olin Library. For more informa- candidate in the Department of What a ShOW Agnes Tsang (left), a senior sculpture major, interned with artist Mary Lynn O'Shea tion, call 935-5495. Art History & Archaeology. at the Clayton Art Fair last weekend. The program — the brainchild of Ron Fondaw, area coordinator The first session at the A recognition ceremony for Kit of ceramics in the School of Art — first pairs students with professional artists, then provides them symposium — "Al Parker, Parker, the illustrator's son, begins with display booths of their own the following year. The Clayton Art Fair is the third-largest event of Practitioner: Ahead of the at 3:45 p.m., followed by a final its kind in the United States, drawing some 160 artists and 140,000 attendees. Curve?" — begins at 10 a.m. and session — "Rebuttal and Synthe- features a panel of contemporary sis; History and Practice" — at 4 illustrators moderated by D.B. p.m. A reception will follow, from Noted economist Frank to give Assembly Series lecture Dowd, associate professor in the 5-7 p.m., in Special Collections.

BY KURT MUELLER Business Week's Hjp-r^-^^jj annual list of Assembly Series Sports Economist Robert H. Frank will top 10 books. In it* give an Assembly Series lecture addition, Frank Who: Economist Robert H. Frank at 11 a.m. Wednesday in Graham co-wrote the tie over the weekend in Chapel. newly published What: Assembly Series lecture Football victorious jfcsBlHHi^* Wisconsin. The Bears looked Frank is the Goldwin Smith "Principles of Where: Graham Chapel in home opener in good position for a win Professor of Economics, Ethics Economics." A When: 11 a.m. Wednesday Sept. 5 against Principia and Public Policy at Cornell noted essayist, The Bears passed a big early test College, but the Panthers University, where he also holds a Frank is a as they won their ninth-straight overcame a 1-0 deficit with joint appointment in the frequent home opener with a 17-14 two goals in the final nine university's Johnson School of contributor to The New York for Advanced Study in Behav- victory Saturday over Illinois minutes to pull out the win. Management. His writing and Times. ioral Sciences (1992-93) and Wesleyan University. The Bears WU then played to a scoreless research focus on economics and Frank earned a bachelor's most recently, a visiting profes- scored 17 unanswered points draw with the University of social policy issues. degree in mathematics from sor of American civilization at over the second and third Wisconsin-Eau Claire He has authored a number of Georgia Institute of Technology the Ecole des Hautes Etudes en quarters, and the defense held Saturday but finally took out books, including "Choosing the in 1966, then he took a two-year Sciences Sociales in Paris. - twice on fourth down in the its frustrations with a 7-0 Right Pond: Human Behavior and hiatus to teach math and science All Assembly Series talks are final two minutes to hang on blanking of the University of the Quest for Status," "Passions as a Peace Corps volunteer. He free and open to the public. For for the win. Sophomore tailback Wisconsin-Stout on Sunday. Within Reason: The Strategic Role earned a master's degree in more information, call 935- Bobby Collins had his second Jessica Glick tied the school of the Emotions," statistics and a doctoral degree in 5285 or visit the Assembly straight big game, rushing 26 single-game record with four "Microeconomics and Behavior" economics, both from University Series Web site, wupa.wustl.edu/ times for 92 yards. Senior wide goals and added an assist as and "Luxury Fever." In 1995, of California, Berkeley. assembly. receiver Jim Donley played his the Bears rolled to the 7-0 Frank co-wrote "The Winner- He has taught at Cornell for The Assembly Series lecture first game since recovering from win. Megan Drews had a goal Take-All Society," which received a nearly 30 years, during which he by Dave Hickey that had been a dislocated toe and caught six and an assist and Samantha Critic's Choice Award, was named also served as chief economist for scheduled for Wednesday was passes for a career-high 119 Sussman and Kim Raess also a Notable Book of the Year by The the Civil Aeronautics Board canceled due to the cessation of yards and a touchdown. scored. New York Times and was listed in (1978-80), a fellow at the Center the nation's flights that morning. Volleyball wins 4, takes WU Classic Cross country teams peptides, genes, proteins and small place well in opener Her work was cited in the July The University's fourth-ranked molecule drugs for delivery in the issue of Discover as a finalist for volleyball team posted four The 2001 season-opening race body. Award the annual Discover awards. She is wins en route to the Washing- was a good one for the Wooley earned a bachelor of widely considered to be in the ton University Classic champi- University cross country Wooley named winner science degree in chemistry from forefront of the emerging field of onship last weekend. The Bears teams as the women placed Oregon State University in 1988 of Cope scholar award nanoscopically defined organic defeated Westminster College, second out of 16 teams and — from Page 1 and then studied under the materials. University of St. Francis, the men's team placed fifth direction of Jean M. J. Frechet, Wooley is perhaps best known Webster University and out of 16 at the North Central Ph.D., at Cornell University, "This is wonderful news," said for her creation of tiny synthetic Concordia College (Minn.). College Alumni Meet in obtaining a doctorate in polymer/ Joseph J.H. Ackerman, Ph.D., the polymer particles that mimic Katie Quinn, Rebecca Rotello Naperville, 111. The women's organic chemistry in 1993. She then William Greenleaf Elliot Professor viruses and show potential for a and Colleen Winter were team finished with 81 points, began an academic of Chemistry named to the all-tournament 19 behind first-place finisher career as an and depart- team. Quinn collected 37 kills Wheaton College. The men's assistant professor ment chair. and hit .541 for the weekend; team finished with 141 points. of chemistry at "Congratula- "This is an extremely prestigious award that reflects Rotello finished the tournament Washington tions to Karen with 137 assists and 35 kills. Wooley, and to well on Washington University. It's an excellent way University and was the department to begin the new school year." promoted in 1999 Men's soccer drops 2 This is an to full professor extremely JOSEPH J.H. ACKERMAN with tenure. in Chicago tourney prestigious Since 1996, The men's soccer team traveled award that reflects well on new direction in gene therapy and Wooley also has held an appoint- to the SCAC/UAA Tournament ment in the Division of Biological Washington University. It's an other biomedical applications. The in Chicago last weekend and and Biomedical Sciences Bioor- excellent way to begin the new nanoparticle goes by the descrip- came home with two 2-1 losses. ganic Chemistry Program. Her school year." tive name of knedel (k-ned-1), for On Sept. 7, the Bears lost their research interests include the Wooley's award citation notes its similarity to a popular Polish first game of the year, to the synthesis and characterization of "her seminal accomplishments at dumpling. The knedels are shell University of South, and then degradable polymers, unique the interface of organic, polymer cross-linked structures surround- lost to Rhodes College Sunday. macromolecular architectures and and materials chemistry, including ing a hydrophobic, or water Jeff LaBoskey, sophomore Steve the development of methodologies insoluble, core domain. They are complex polymer assemblies, for Bujarski and freshman Matt which she has received young for the preparation of well-defined too small to be seen by the naked Twardowski were all named to nanometer-scale macromolecules, eye (one nanometer is one- investigator awards from the the all-tournament team. shell crosslinked knedel-like billionth of a meter); their National Science Foundation nanoparticles and nanocages, and diameters range from 10 to 100 (1994-99), the Army Research Women's soccer the elucidation of original nanometers. They are actually Office (1996-99) and the Office of Naval Research (1998-2001). She rebounds, wins 7-0 concepts in synthetic polymer close in size to many proteins and Jessica Glick tied the school chemistry for the synthesis of viruses. was named as a DuPont Young The women's soccer team single-game record with four hydrolytically degradable poly- In 2000, Wooley and research- Professor (1996-99). dropped its home opener last goals in a 7-0 win Saturday mers." ers in her lab hollowed out the Wooley currently serves the ACS week but then improved to 2-1- over the University of Wooley's research has drawn knedel core to produce Division of Polymer Chemistry as 1 on the year with a win and a Wisconsin-Stout. considerable professional and "nanocages," into which someday the publications chair and as an popular interest in recent years. researchers might be able to pack alternate councilor. 6 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Wrighton, Fields reach out at vigil

A candlelight vigil was held in Brookings Quadrangle Blood donation information Tuesday night that allowed students, faculty and staff to come together to reflect on the 1 n the wake of Tuesday's Student Center day's tragic events. Chancellor 1 tragedies, there will be an Nov. 1: 3-8 p.m., Fried- Mark S. Wrighton and Wayne urgent need for blood man Lounge, Wohl Student Fields, Ph.D., the Lynne Cooper donations for weeks to come. Center Harvey Distinguished Professor Upcoming blood drives on If you would like to receive in English and director of campus: additional information, as it is American cultures studies, both Oct. 1: Noon-5 p.m., the available, about future blood in Arts & Sciences, were among Gargoyle, Mallinckrodt drives accessible to the Univer- the faculty and student speakers Student Center sity community during the at the ceremony. Below are Oct. 2: 3-8 p.m., Friedman coming weeks, please e-mail , Victor T. Le Vine, Ph.D., professor of political science in Arts & Wrighton's and Fields' remarks. Lounge, Wohl Student Center [email protected] Oct. 3: 3-8 p.m., Friedman and ask to be added to the Blood Sciences, and Carol S. North, M.D., professor of psychiatry at the Chancellor Wrighton Lounge, Wohl Student Center Drive Announcement List. School of Medicine, speak at a news conference Tuesday morning. Oct. 4: Noon-5 p.m., the You may also consider The tragic events today sadden planned and well-organized." all of us. We gather this evening Gargoyle, Mallinckrodt making a monetary donation North said people will be as a community concerned for Student Center to the American Red Cross to Tragedies affected in varying ways by this our families, our friends and our Oct. 29: Noon-5 p.m., the support its disaster assistance tragedy. graduates who may have lost their Gargoyle, Mallinckrodt efforts. Donations can be — from Page 1 "Some people with previous lives or who may have been Student Center mailed to American Red trauma experience may be injured. For many there remains Oct. 30: Noon-5 p.m., the Cross, 4050 Lindell Blvd., St. ranted at this time. "We still don't know enough sensitized," North said. "Other the uncertainty of whether those Gargoyle, Mallinckrodt Louis, MO 63108, or to be able to do anything more people with past trauma may find we love and care for are safe. At Student Center American Red Cross, P.O. than simply some elementary strength from having dealt with it times like these, we naturally Oct. 31:3-8 p.m., Box 37243, Washington, D.C. before. We know the people most reach out to touch our family Friedman Lounge, Wohl 20013. speculation. To speculate unnecessarily is to sew the seeds likely to be seriously affected are members, to affirm their safety those with previous psychiatric and to seek consolation and of panic. We are all terribly pained by these events and are illness. Those closest to the direct support. For many gathered here You have my continuing a new and terrible way. And the waiting further developments." impact will have higher rates of this evening, you are far away appreciation and admiration for greatest resource we bring to Le Vine said the events were symptoms." from home and concerned for your commitment to a caring this difficult moment are the not part of a spontaneous She said the most common your families and friends and community. Thank you again for people surrounding us, the operation. types of reactions people have after they are likewise concerned coming this evening. affection that, as much as all of "The amount of coordination these types of events are shock, about you. our practical considerations, needed for this was immense," disbelief, a feeling of unreality and We gather as your Washington Wayne Fields joins us together. Le Vine said. "You needed to possibly numbness. University family. Our commu- In a moment such as this, Tonight and in the days to hijack three or four airplanes; "People tell us the most effective nity is one that cares for one when so many families suffer so come, we must do the work of you needed to plan; you needed form of coping is to lean on loved another, and we now must deeply, so terribly — in a sisters and brothers, comfort- to round up the people; and you ones, to talk it out, to develop support each other. We come moment such as this, no matter ing, supporting, even protecting needed to find people willing to meaning, to process things from all parts of the United States how old we are, it is family we each other. It is not enough that sacrifice their lives. So this means psychologically," she said. "It is and the world, concerned for most desire, parents and siblings, we merely live through the preparation of at least a month in important to get people who are those who have died or have been those who know and love us best. approaching days; we must advance. very upset to psychiatric help to harmed today. Our heart goes out In our anxiety, we want to be come through with decency as "This was not something done evaluate them and determine what to their families and friends, reassured; in our grief, we want well as bravery, humanity as on a whim. It was very well- type of treatment can be done." some who are here tonight. Our to be comforted; in our uncer- well as courage; we must come concern extends to all affected, tainty, we want to be loved. through this together, whole because we value human life. Amidst so much fear, we long for and complete. This — as much In the aftermath of the events the haven of home. as justice — do we owe to those "We must continue to uphold the utmost respect for the of today, emotions and tension But tonight many of us are who have been most wounded, diverse people who constitute the Washington University will be high. I would like to far-removed from our parents to those who have died, and to remind you that the great and our siblings, miles away from their families as well as to community. People from all areas of the world learn, live expectation I have for each of you where we long to be and from ourselves and to our families. and work at the University, and it is especially important at is that you will always show those to whom we most naturally As a 60-year-old child I am, this tragic time that the highest respect be shown to all respect for others, both here on turn for solace and support. this day, unashamedly afraid, campus and in the community Rather we are here, and we are afraid for my country, afraid for humanity on and off campus." that surrounds us. together, and we must be as myself and those I love, afraid MARK S. WRIGHTON I thank you for your caring family to one another, sustaining for the things I most believe are response to those in need, to the one another — every one of us good and right. As a parent, I call for assistance, and for your — as sisters and brothers do. am distraught with my power- regarding any developments that caring participation tonight. The test of a community, lessness, the awful knowledge affect the University community. These will be trying days as the especially one so diverse and that I cannot protect my Community The University hotline — 935-0014 scope of the tragedy we have contentious as ours, is the depth children, cannot watch over — from Page 1 — will be updated routinely to experienced becomes better- of our commitment to one them and keep them from provide additional information. defined. Our community will another, is its ability — our harm. As a child I ask for your world learn, live and work at the An e-mail was sent to every continue to rally to support each ability — in the midst of comfort and support. As a University, and it is especially student, faculty member, and staff other. I am personally grateful for confusion and doubt, to trust and parent, speaking for all parents, important at this tragic time that member at the University, sharing the support that has already been uphold one another rather than I beg you — the highest respect be shown to this information with them and given to me and to those respon- to divide and break. This country Take care of one another. all humanity on and off campus." assuring them that every effort is sible for the safe and secure is being tried in a new and Take care of one another. The University will provide being made on their behalf, environment we enjoy here. terrible way; we are being tried in Take care of one another. regular updates on its Web site Wrighton said.

receive," Grigsby said. normal-sized lymph nodes*PET, Campus Watch PET PET's superiority in detecting however, does have a limit of the spread of cervical cancer is detection, and it will miss tumor- — from Page 1 due to a fundamental difference containing lymph nodes if the The following i icidents were reported to University Police Sept. 4-10. Readers with in the two technologies. CT scans information tha t could assist in investigating these incidents are urged to call! 35-5555. number of cancer cells is too low. This informatio n is provided as a public service to promote safety awareness found them in seven women; produce an X-ray image of a thin PET scans also provide images and is available on the University Police Web site at rescomp.wusll.edu/-wup J. PET identified abnormal cross-section of the body. To of the entire body. supraclavicular nodes in eight diagnose the spread of cervical "A patient's PET scan shows Sept. 4 application of warra its. women, whereas CT found none. cancer, radiologists study the up on a computer monitor," 2:52 p.m. All abnormalities detected by CT images for abnormally enlarged — An unknown Sept. 7 Grigsby said. "It shows an person br ake into a car parked ,, ' also were detected by PET. lymph nodes, those greater than anatomical outline of the patient in Wohl G arage and stole stereo U:49 a-m" ~ ^ un known "We were surprised to find 1 centimeter in diameter. Lymph in 3-D, and the image is slowly equipmen t. Total loss is valued Person us?d shavin8 cream to that these patients had more nodes are likely to be enlarged rotating. I can see the cancer that at $395. write on the stairwa r walls traces of tumor in their lymph because they contain cancer cells I found during the pelvic exam, leading from the firs t to the nodes than we previously that have spread from the and I can see the abnormal lymph Sept. 5 fourth floor of Myei s Resi- suspected," Grigsby said. "These primary tumor. nodes that I wouldn't have known dence Hall. The van dalism findings are so significant that we "The problem is that lymph existed without the PET scan. 1:15 p.m. — A University occurred between 8 p.m. Sept. have stopped using CT scans for nodes that are not enlarged also And that means I can more employee reported at 1:15 p.m. 6 and g a m Sept 7 There tumor evaluation in patients with can have tumor cells, and these accurately, more effectively, a white m ale with dark hair and were no witnesses to the cervical cancer." nodes will go undetected in CT deliver that patient's treatment." a yellow s! lirt stole a Spann cart incident In fact, he said, "PET findings scans," Grigsby said. Commenting on the study, that was p arked on the south altered treatment for about half PET scans, on the other hand, David Mutch, M.D., the Ira C. side of Ol n Library. The cart Sept. 10 the women in the study." It reveal a metabolic — rather than and Judith Gall Professor of was later i ecovered on the east . T T . MillanHallbya 5:54 p.m.-A Umv :rsity helped some avoid unnecessary anatomical — difference Obstetrics and Gynecology and side of Mc Spann em i e student struck a par ced car surgery by revealing that their between cells and structures. In head of the Division of Gyneco- while in the Lien Ga rage cancer was more advanced than this study, PET detected the logic Oncology, said: "This gives 7:20 p.m. — Two University between 4:15-5 p.m. The difference in the way cells first thought. In others, PET us another tool to evaluate students v\ 'ere found smoking student stated that h e did not helped better define the radiation consume glucose, a simple sugar whether a patient has metastatic marijuana behind Shepley realize he caused am r damage dose, the size of the area requir- required by cells to live and grow. disease before we operate, and it House. Bo th students were taken t0 the unoCcupied v< :hicle. ing irradiation, or both. Cervical cancer cells grow at a can help us avoid surgery if it is to the Uni versify Police station. Total damage is unk nown. "Based on our results, we faster rate and therefore have a not appropriate. It's still not 100 One stude nt was released and A ... . ., TT . believe that clinical trials higher rate of glucose consump- percent accurate, but it's the best referred to the Judicial Adminis- Additionally, Umven ity Police comparing treatments for tion than the normal cells tool available to help in determin- trator; the other student was responded to two rep orts each of cervical cancer should use PET to making up the lymph node. ing which patients need surgery booked or felony possession (™8 offense, theft an d automo- more accurately determine what Thus, PET can often identify the and which patients need radiation charges an d released pending blle ac"dent' and om i report of treatment each patient should presence of cancer cells in therapy." vandalism. record.wustl.edu WASHINGTON UNIVERSITY IN ST. LOUIS Sept. 14, 2001 7

chemistry, and his students at the that distant molecules in an in solution, but a goal is to Kirmaier, Ph.D., research University of California, array can communicate through develop optoelectronic switches associate professor of Switch Riverside. superexchange, they are better that respond directly to light chemistry, have been working • from Page 1 "It has been a big mystery why able to experiment with designs and can operate in the solid on photosynthesis for nearly the T gate arrangement works as that work more efficiently and state. 30 years to understand the activating it to rapidly accept well as the linear arrangement," bring about different functions. "With the correct design, we mechanics of the photosyn- energy. At this juncture the Holten said. "Now, we've been "The knowledge that our can control this process with thetic system and the energy in the wire has been able to show that the T gate collaborative work has uncov- two different colors of light properties and function of blunted, or quenched, and functions efficiently in both the ered over the past several years rather than with electrochemis- porphyrins. instead of light going out, heat is on and off states because the gives a better understanding of try," Holten said. "The next "We've expanded into released. That is known as molecules are able to communi- molecular switching and generation of these switches will molecular photonics through controlling the switch cate distantly through the array, enables us and others to tailor use, for example, blue light to our terrific collaboration porphyrin's redox state. All these namely between the switch and molecular design for better flow initiate energy flow along the with Jon Lindsey and Dave functions happen incredibly fast output molecules, even if of energy and charge in order wire to cause red light output at Bocian in just the past six — in picoseconds, a trillionth of removed from one another." make novel wires, gates and the other end, and green light to years," Holten said. "At this a full second. The results were published in a light-harvesting arrays," activate the switching function point in the research, we've Holten and Lammi studied recent issue of the Journal of Holten said. and turn the output off." provided an infrastructure of the operation of the molecular Physical Chemistry, and Lammi An ultimate goal of this line Many of the molecular arrays different molecular architec- switches in Holten's laboratory, a discussed the research and other of research is to create molecu- that Holten, Lindsey and Bocian tures and an increased high-technology maze of ultra- results at the American Chemical lar arrays and building blocks create and test are photosynthe- understanding of how the high-speed lasers, mirrors, lenses Society's national meeting August for use in molecular photonics, sis analogs. In photosynthetic molecules work and can be and machinery. The porphyrin 26-30 in Chicago. The collabora- solar energy conversion, and bacteria and plants, light is tuned to have desired arrays were synthesized by John tive research between the groups nanotechnology. In one near absorbed by arrays of antenna properties. Robin Lammi's Lindsay, Ph.D., professor of at Washington University, North term project, the chemists want pigments and goes to special studies show we understand chemistry, and his students at Carolina State University and the to extend the operation of their proteins called reaction centers the current molecular redox- North Carolina State University, University of California, River- molecular switches. Currently, where electrons move across based switches quite well now and key functions of the mol- side, is sponsored by the National the experiments use electro- membranes, converting light and give us insights to ecules were studied by David Science Foundation. chemistry involving electrodes energy to chemical energy. advance the designs to the Bocian, Ph.D., professor of Now that researchers know to activate the switching action Holten and his wife, Christine next stage." Washington University Drug and Alcohol Policy The Washington University Record publishes this policy as a service to the University community.

ordinances and statutes, contact the Office of the Executive Moderate to high doses of alcohol cause marked impair- I. Introduction and Policy Statement Vice Chancellor and General Counsel (935-5152). ments in higher mental functions, severely altering a Washington University is unequivocally opposed to the person's ability to learn and remember information. Very misuse of lawful drugs and the possession and use of IV. Health Risks high doses cause respiratory depression and death. If unlawful drugs. Pursuant to the requirements of the Drug- A. Drugs combined with other depressants of the central nervous Free School and Community Act Amendments of 1989, Severe health risks, including death, are associated system, much lower doses of alcohol will produce the effects Public Law 101-226, Washington University adopted the with the use of illicit drugs. Below are some of the health just described. following Drug and Alcohol Policy. risks related to each substance. For further information, Repeated use of alcohol can lead to dependence. Sudden The law requires that, as a condition of receiving federal contact the University Health Services (Hilltop Campus, cessation of alcohol intake is likely to produce withdrawal funds or any other form of financial assistance under any 935-6666; Medical Campus, 362-3523). symptoms, including severe anxiety, tremors, hallucinations federal program, Washington University must certify that Anabolic Androgenic Steroids — Steroid users can and convulsions. Alcohol withdrawal can be life-threaten- it has adopted and implemented a program to prohibit the experience serious cardiovascular, liver, central nervous ing. Long-term consumption of large quantities of alcohol, unlawful possession, use or distribution of illicit drugs and system, gastrointestinal and reproductive disorders. In particularly when combined with poor nutrition, can also alcohol by students and employees on its property or as a many, use can result in testicular atrophy, sterility, lead to permanent damage to vital organs such as the brain part of any of its activities. impotence and arrested growth. Irreversible masculiniza- and the liver. It is the goal of Washington University to protect the tion and sterility can result when women use steroids. Women who drink alcohol during pregnancy may give public health and environment of members of the Psychological impairments include mood swings, birth to infants with fetal alcohol syndrome. These infants University by promoting a drug-free environment as well depression and very aggressive behavior. have irreversible physical abnormalities and mental as one free of the abuse of alcohol. Depressants — The use of depressants can result in a retardation. In addition, research indicated that children of The manufacture, distribution, possession or use of change in tolerance and physical as well as psychological alcoholic parents are at greater risk than other youngsters of illicit drugs and the unlawful possession, use or distribu- dependency. The combining of several depressants (e.g. becoming alcoholics. For further information, contact the tion of alcohol on Washington University property or as a valium and alcohol) will potentiate the depressant effects, University Health Services (Hilltop Campus, 935-6666; part of any of its activities is prohibited. multiplying the health hazards. Withdrawal systems Medical Campus, 362-3523). Violations of this policy will be handled according to include anxiety, vomiting, acute psychotic episodes, existing policies and procedures covering the conduct of seizures and death. V. Drug and Alcohol Counseling, administrators, faculty, students and staff. Hallucinogens — Large doses of phencyclidine (PCP) Treatment or Rehabilitation or may result in a convulsive seizure, coma and death. Mood II. Standards of Conduct disorders occur and the user may become violent, Re-Entry Programs A. Illicit Drugs: The unlawful manufacture, possession, irrational and potentially harmful to self and others. A. University resources include the University Health distribution or use of illicit drugs on Washington Univer- Lysergic acid (LSD), mescaline and Psilocybin cause Services (Hilltop Campus, 935-6666; Medical Campus 362- sity property or as part of any of its activities by University sensations and feelings to change rapidly. The user may 3523), the Psychological Service Center (935-6555) and the students, employees or their guests is prohibited. experience panic, confusion, anxiety, depersonalization Department of Psychiatry (362-7002). B. Alcohol: Federal legislation prohibits the unlawful and loss of control. While relatively rare, flashbacks, the B. Numerous non-University counseling programs exist in possession, use or distribution of alcohol. The possession spontaneous reappearance of the drug experience after the St. Louis metropolitan area. Many programs advertise and use of alcohol by non-intoxicated persons twenty-one use has ceased, may occur. extensively in local media. Consultation with one's personal (21) years of age or older is, according to Missouri law, Narcotics —■ Tolerance, especially to the euphoric physician is advised prior to self-referral to such non- lawful. University policies limit the lawful use of alcohol to effect of narcotics and physical dependence develops University programs. For further information regarding appropriate occasions. Undergraduate students should rapidly. In order to avoid the abstinence syndrome, the referral to such programs, contact the University Health contact the Office of Student Affairs for standards addict becomes preoccupied with acquiring the drug. Service or your private physician. governing student parties and student use and possession Withdrawal symptoms are extremely uncomfortable; of alcohol. Graduate students should contact their Dean's however, they are seldom life-threatening. VI. Disciplinary Sanctions office. Stimulants — High doses of stimulants result in Different disciplinary procedures are applicable to faculty, intense personality disturbances including visual and staff and students. Violations of the standards of conduct III. Legal Sanctions auditory hallucination, delusions and paranoia. Tolerance will be dealt with on a case-by-case basis with imposition of A. Drugs: The manufacture, possession, sale, distribution develops rapidly. Cross-tolerance does develop among discipline being appropriate to the severity of the violation. and use of illicit drugs is prohibited by city and county stimulant drugs (e.g. methamphetamine and cocaine). For each group comprising the University community, there ordinance, state law and federal statute. Punishments The use of cocaine can cause death by cardiac arrest or are certain common sanctions that could be applied in an range from fines of $50 to life imprisonment. The statutes respiratory failure. Stimulants are addictive and while appropriate case. These common sanctions include letters and ordinances define the drugs deemed "illicit." Chapter withdrawal from stimulants is less dangerous than with of reprimand, probation and severance of ties with the 195 of the Revised Statutes of Missouri addresses illicit depressants, depression can make a person vulnerable to University, through expulsion or termination. Normally, drugs. Section 195.214 of the Missouri statutes specifically suicide. opportunity for referral to an appropriate rehabilitation prohibits the distribution of any controlled substance on Cannabis — The mood-altering effects of marijuana program occurs and is usually associated with a first University property. Persons convicted of this offense can are the result of the chemical delta-0 tetrahydrocannab- offense. Referral for prosecution will occur for serious be sentenced to imprisonment for not less than ten (10) inol (THC). THC is fat-soluble and can remain in the violations. years. body up to three weeks after smoking one marijuana A. Faculty The Federal Controlled Substances Act prohibits the cigarette. Consequently, even the occasional user can be Faculty discipline is normally administered, in the knowing, intentional and unauthorized manufacture, detected through urinalysis. Research indicates that informal manner, by the faculty member's department head distribution or dispensing of any controlled substance or regular use may have long-term effects on the user's or dean. Faculty members can be terminated for cause only the possession of any controlled substance with intent to brain, heart and reproductive organs. The numerous after a hearing conducted before a panel of faculty peers. manufacture, distribute or dispense. Federal law also carcinogenic chemicals found in marijuana make it B. Staff prohibits the knowing intentional and unauthorized particularly harmful to the lungs. Loss of memory, lack of The non-academic staff is subject to disciplinary creation, distribution, dispensing or possession with intent motivation and diminished attention span are some of procedures administered by the staff member's department to distribute or dispense of a "counterfeit substance." the effects of regular marijuana use. Long-term use may in consultation with the Human Resource offices on the To review specific provisions of applicable ordinances result in psychological dependence and change in Hilltop and Medical Campuses. The normal range of and statutes, contact the Office of the Executive Vice tolerance. personnel actions could occur. Staff members are entitled to Chancellor and General Counsel (935-5152). B. Alcohol a hearing and redress by a panel of peers. B. Alcohol: Missouri's Liquor Control Law makes it illegal Abuse of alcohol can produce severe health risks, C. Students for a person under the age of twenty-one (21) years to including death. Alcohol consumption causes a number The University Judicial Code governs students' conduct purchase, attempt to purchase or possess any intoxicating of marked changes in behavior. Even low doses signifi- and establishes procedures for adjudicating complaints liquor (Section 311.325 RSMo.). Violation of this provision cantly impair the judgment and coordination required to against students. Expulsion is the most severe sanction can subject one to a fine between $50 and $1,000 and/or drive a car safely, increasing the likelihood that the driver possible. In addition, residence halls (including fraternity) imprisonment for a maximum term of one year. County will be involved in an accident. Low to moderate doses of can impose discipline upon residents. The University may and municipality ordinances contain similar prohibitions alcohol also increase the incidence of a variety of terminate the residence hall contracts of students violating and sanctions. To review specific provisions or applicable aggressive acts, including spouse and child abuse. its standards. 8 RECORD WASHINGTON UNIVERSITY IN ST. LOUIS Sept. 14, 2001 Washington People

Iaving spent much of his life in India and Thailand with a father who worked for the H United Nations, Gautam N. Yadama, Ph.D., associate professor in the George Warren Brown School of Social Work (GWB), seemed destined for the field of international development. His area of expertise com- bines analysis of social, political and economic theory, fieldwork studying governance of common resources in developing nations and policy recommendations to improve the lives of the poor and marginalized who are dependent on these resources. Yadama recalls traveling as a child with his father throughout much of South Asia to assess the Gautam N. Yadama, Ph.D., associate professor in the George Warren Brown School of Social Work resource potential of the tropical (GWB), meets with Guzal Kamalova (left) of Uzbekistan and Darikhand Bayar of Mongolia, who are forests. studying at GWB as Open Society Institute fellows.

the faculty in 1991, has been closely involved in the school's Advancing collaborative community efforts partnership with the Open Society Institute. The program brings students to GWB from "When most people think of governance of these resources." so that it addresses the rights of Mongolia and former Soviet Gautam N. Yadama, the tropical forest, they imagine Yadama's fieldwork among those at the margins of society, Union countries to train them as its spectacular beauty — what you forest-dwelling tribal communi- including women and children. the first wave of professional Ph.D., seeks to might see captured in National ties brings new insight into the To gain insights into the role of social workers in their homelands. Geographic-type photos," Yadama roles of social capital, mediating advocacy in the United States, As coordinator of GWB's improve the lives of said. "But what struck me was the groups such as nongovernmental several of the master's degree law concentration in social and extreme poverty of forest agencies, governance structures, students are observing Washing- economic development, Yadama the poor and communities. In spite of the conditions for creating trust and ton University School of Law's stresses to his students not only abundance, I was impressed by reciprocity, and institutional clinical program this semester. the complexity of international marginalized who just how difficult their lives were, arrangements that ensure Under the partnership with development, but also how as they struggled between an enforcement and accountability. Tribhuvan University, Washing- lessons learned in developing are dependent on oppressive state and predatory His work has been published as ton University students also have countries can offer insight into markets to eek out an existence." resource papers for the United pursued public policy internships addressing problems among other common resources Later, as a graduate student at Nations, as policy analyses for in Nepal's emerging democracy. marginalized groups, such as the the Mandel School of Applied international development Five social work students, four urban poor in the United States. Social Sciences at Case Western organizations, in professional law students and three dual His approach encourages students Reserve University, Yadama journals and as chapters in books degree students have worked on to expand their horizons. BY ANN NICHOLSON became interested in community- on development and resource projects with grass-roots "Dr. Yadama's commitment to based, resource-management management. organizations. Their efforts bringing an international programs being launched in many "Gautam's research and furthered policy initiatives perspective to the M.S.W of these same tropical forests. His publications reflect a wonderful ranging from combating sexual program combined with his own doctoral thesis compared combination of key questions, trafficking of girls and women to experiences outside of the United governmental and nongovern- theoretical insight, innovative promoting micro-finance States inspired me to pursue my mental community forestry research projects, skilled data practices to creating sustainable dream of a career as an interna- initiatives in Andhra Pradesh, collection and analytical sophisti- development programs to assist tional social worker," said Felecia India. His subsequent research cation," said Michael W. the poor. Bartow, who graduated with an looks at how communities act Sherraden, Ph.D., the Benjamin E. Jane Aiken, J.D., professor of M.S.W. in 2000 and now serves as collectively to govern community Youngdahl Professor of Social law who is currently in Nepal on program coordinator for the forests that are under increasing Development and director of a Fulbright grant helping the Midwest Immigrant and Human market and population pressures GWB's Center for Social Develop- program explore clinical educa- Rights Center in Chicago. "He in India, Nepal, Bhutan and ment, under which Yadama has tion initiatives, spoke highly of challenges students to strive for Turkey. His focus is how local conducted research initiatives. "His Yadama's contributions. the highest possible standards of communities and the state can extraordinary international work "Anyone who knows Gautam academic and professional put aside their historic differences in India, Nepal, Bhutan and other knows that he is a man of tireless excellence." and make credible commitments countries in South Asia also energy and expansive ideas," 2001 M.S.W. graduate Kelly to working together to attain enriches the research and educa- Aiken said. "He is a true force in Corley, who pursued a social sustainable development. tional atmosphere at GWB, and moving Washington University policy in law internship in Nepal, Yadama cautions that creators enhances the University's efforts to toward more interdisciplinary said Yadama was an ideal mentor. of development programs must build stronger ties to Asia." and international approaches to "Dr. Yadama pushes students first understand the historic, During the 2000-01 academic scholarly inquiry. His drive, to go beyond what they think they cultural, social, political and year, Yadama carried over his intelligence and ability to connect are capable of," Corley said. "He economic dynamics that can knowledge of collective action in with people in many disciplines encourages all of us to step complicate state and community forestry communities to his and many countries are outside of society's boxes and cooperation. For instance, in research into collaborative invaluable." look at the world from a different India, colonial and post-indepen- community efforts in urban At GWB, Yadama incorporates point of view — especially if it is dence state policymakers viewed areas in Nepal. Under a J. his international perspective into one we are not comfortable with. native tribes as indiscriminate William Fulbright Foreign his teaching and his efforts to He is the type of person that just users of forest resources who Scholarship grant, he surveyed attract students from other to be around him makes you feel hampered the state's ability to 150 communities and inter- countries. Yadama, who joined like doing great things." maximize profits in timber and viewed 600 households about mining industries. institutional arrangements — "The resulting policies were both within their communities not only alienating, but also and in conjunction with the state increased the hardships of — to supply and maintain public vulnerable groups whose survival goods in neighborhoods. His is linked to forest use," Yadama research, which will be published said. "These policies failed to as a book, will further the policy recognize that before state debate as to why some impover- intervention, forests were being ished communities are more managed as common property successful than others in guided by institutional norms of providing public goods, such as tribal communities. safe and adequate streets, clean . "Today, the most effective water supplies, sewage systems policies are centered around state and garbage disposal. and community forest co- In 1999, Yadama's creation of Gautam N. Yadama, Ph.D. management, where communities the Social Policy in Law Program and the state both have a stake in at Tribhuvan University in Nepal enhancing forest conservation also built on his interests in Degrees: B.S., Wilkes College; M.S. while mutually sharing in the addressing the needs of the and Ph.D., Case Western Reserve benefits. Given the historical disenfranchised and his commit- University tensions and current competing ment to interdisciplinary Languages: Telugu, Hindi and Nepali interests in forestry resources, approaches to solving social reaching this equilibrium can be a problems. Family: Wife, Shanta Pandey, long and difficult process. The program seeks to train associate professor at GWB; son, Essential to achieving this goal Tribhuvan University law Yadama visits with a Bhutanese villager during fieldwork in the Paro Sagar, 8; daughter, Aishwarya, 5 will be direct inclusion of the students in how to shape Nepal's Valley of Bhutan. Yadama was researching how governmental policies poor and marginalized in the social and political infrastructure enable communities to manage the region's community forests.