Sept. I 5, I 992 Vol. XLIV No.19 "Still U.S. Department of Health The Second and Human Services Best Thing

National Institutes of About Payday" Health Phased Occupancy Planned The Record Silvio 0. Conte Building Completed On Time, Within Budget By Rich McManus

The most modern research facility at NIH­ the Silvio 0. Conte Building-has just been completed on time and within budget by the Division of Engineering Services (DES). Dedicated to research on child health and neurosciences, the $72 million facility honors the late Rep. Silvio Conte, who helped break ground on the project 4 years ago. Conte, a Massachusetts Republican, was an ardent supporter of biomedical research in Congress for many years. He called the groundbreaking ceremony in 1988 the proudest day of his political career. The legislator died in 1991 at NIH, where he had been treated for cancer. "This building meets all state-of-the-art standards," said John Pallas, chief of the Design and Construction Branch (DCB), DES. "It was a very difficult facility to design because it colocates office space, laboratories and animal space. All of these uses require different ventilation, cooling and heating needs. It's a very unusual mix." Some 550 researchers and support staff from The Silvio 0. Conte Bldg. (Bldg. 49) will be dedicated Sept. 17 in honor of the Massachusetts congressman seven institutes are expected to take occupancy who was a strong advocate ofbiomedical research. Seven institutes will share space in the state-of the-art of the Conte Bldg. A year-long "coordinated facilitydevoted to child health and the neurosciences. Standing out front ofthe facility are Division of Engineering Services workers who spearheaded the construction effort: (from 1) Frank Kut!ak, John Pallas, occupancy phase" is(See scheduled CONTE to BLDG., start moving Page 8) users into the building late this year or in early Cyrena Simons, Ernest Lunsfordand Stephen Hagan. NIH Team To Repair Florida NIAAA Research: From Cell to Society Primate Center Hit by Andrew By Ann M. Bradley By Rich McManus (Part I of a three-part series examining the three new institutes slated to join NIH on Oct. I, when A the NIHIADAMHA merger takes effect.) Created in 1970, at the urging of persons whose lives had been affected directly by alcohol seven-man team of volunteers from NI H's problems, NIAAA first was charged with Division of Engineering Services left Sept. 2 on /n 1791, the College of Physicians of Phila­ addressing the severe public health need for a 14-day mission to clean up the NIH Perrine delphia petitioned the newly formed U.S. treatment of approximately 10 million persons Primate Center in Florida, damaged during Congress to take action against alcoholism. with alcoholism. Only during the past decade Hurricane Andrew. "The center, owned by Likening the disease to a plague, the physicians has the institute's exclusive mandate been NIH but licensed to the University of Miami, is asked whether any government faced with research, research training, and research home to a valuable outdoor breeding colony of alcohol-associated health and social problems dissemination. rhesus and cynomolgus macaque monkeys, none could fail to take major action. NIAAA's first decade was devoted largely to of which were infected or currently involved in Major action(NIAAA), in modern times centers in the developing a national treatment network and research," said Dr. Jim Taylor, deputy director National Institute on Alcohol Abuse and eliminating barriers to care. In addition, the ofNIH's Office of Animal Care and Use. Alcoholism the lead federal agency institute conducted education and information Three hundred-fifteen monkeys were housed for research on the causes, consequences, campaigns on alcoholism as a disease rather in some 34 outdoor cages at the facility when prevention, and treatment of alcohol abuse and than a criminal justice or mental health issue. the storm hit. While most of the colony alcoholism. According to Dr. Enoch Gordis, director since weathered the gale, several monkeys died when NIAAA joins the National Institutes of Health 1985, NIAAA's evolution as a research institute their group housing modules collapsed, and with a 1992 budget of $172 million and almost is essential. others fled the premises once freed, Taylor 300 intramural and extramural program staff. "Until we answer such basic questions as the reported. Fearing that the animals were The extramural program administers approxi­ central and elusive question about alcoholism­ infected, residents of the area shot several mately 700 grants in medical centers and why a pathological appetite for alcohol exists at monkeys, he added. Coast Guard employees are universities across the country. Among the all-optimal prevention and treatment strategies helping local authorities round up escaped grantees are 14 diverse Alcohol Research also remain elusive," he said. macaques. Centers that focus on specific areas of alcohol Gordis views the current reorganization as a The 14-acre center is part of a 58.5-acre tract study, including genetic determinants of alcohol culmination ofNIAAA's research mandate. purchased byNIH in 1982; other agencies lease abuse and alcoholism, pathological conse­ "Our move to NIH offers a clear opportunity to (See PERRINE, Page2) (See NIAAA, Page4) land on the site, located south of Miami, near quences of alcohol abuse, alcoholism treatment, solidify the position of alcohol research in the and alcohol abuse prevention. The Record page 2

Sept. 15, 1992

PERRINE (Continued from Page 1)

Homestead, Fla., the community hardest hit by the Aug. 23-24 hurricane. Three buildings and a trailer form the Primate Center's support space,and all sustained damage; che trailerco was a total loss. All of the outdoor monkey cages were destroyed,but there were no injuries humans, Taylor said. "Perrine is just north of where the eye crossed Florida," he said. He added that new monkey homes were already being procured for installa­ tion by the DES volunteers. "The volunteers will be involved in immediate post-disaster work-picking up debris,repairing fences, making it safe for people to walk around," Taylor continued. 'They will be working under very difficult conditions since there is no power, food, water or accommoda­ DES Direetor Jorge Urrutia (in suit) bids farewell to a team ofvolunteers from his division who are tions. Ir's not a trip to Disneyland."co delivering disaster reliefto the NIH Perrine Primate Center in Perrine, Fla. Theyare (from l) Pete Leading the DES crew is Gerald W. Lawson, Manuel, Elmer M. Lazarus, Roy Wright, team leader Gerald W Lawson, Leo G. Palladini, Harry Hill, special technical assistant the branch chief in and Philip McGee. Behind them is the mobile home the team will live in during the repair operation and the Design and Construction Branch. DES one ofthe trucks in the fleet going to Florida. Director Jorge Urrutia put him in charge of assembling,co on very shoreco notice, a ream of New String Quartet Season Opens workers from a variety of trades and enough power tools, ladders,lights, gas, water,portable equipment respond che disaster. "They phones, faxes and computers, food, dishes, The fourth season of lunchtime concerts atco are casked co cake care only of the most urgent bedding and first-aid kits," enumerated Lawson. NIH by the Manchester String Quartet begins needs," Urrutia said. "They won't be rebuild­ "They tell us we may find ticks, snakes, fire on Sepe. 25. Concercs are held from 12:30 ing the entire center." ants, and scorpionsco down there." He also had 1:30 p.m. in Masur Auditorium,Bldg. 10. About 31DES workers volunteered for duty, truckloads of roofing material, nails and other Other dates for the 1992-1993 season are Nov. which heartened Urrutia andco boosted morale supplies needed get Perrine back on its feet. 23,Dec. 14,Jan. 25,Feb. 15,Mar.15,Apr.12 throughout the shops area of Bldg. 13. The volunteers will work every dayco of the and May 17. D "That was very surprising me,given the week, most likely in high heat and humidity. co conditions they will be workingco under," he said. Lawson received special permission authorize "It's not like goingco to the beach. It is very TheNIH Record overtime compensation for the duration, and Published biweekly at Bethesda, Md., by the Editorial commendable for them do this. They had a execute contracts should outside help be million things put together before leaving Operations Branch, Division of Public Information, for necessary. the informationof employees of the National Institutes of and they did it in a couple of days." "Normally,this is not my job," explained Health, Department of Health and Human Services, and Lawson claimed forhis ream two carpenters,a Lawson,who has never been to Perrine before. circulated to nonemployees by subscription only through welder, an electrician and two equipment "I don't know what we'll find bur we're the Government Printing Office. The content is reprintable operators for the first 14-day shift. After 2 preparing for the worse." without permission. Pictures may be available on request. weeks,a second DES team may join him at Veterinarian Taylor will visit the site in a few Use of funds for printing this periodical has been approved by the director of the Office of Management and Budget ''It's not like going to the beach. It weeks to assess damage to the Perrine com­ through September 30, 1992. pound. An architectural firm will also visit to is very commendablefor them to do inspect the site and estimate the cost of full NIH Record Office Correspondents: • II Bldg. 31, Room 2B-03 CC, Sue Kendall h repair, said Urrutia. t is. Phone 496-2125 DCRT, Anne P. Enright "The facility did not meet AAALAC (Ameri­ Fax 402-1485 DRG, N. Sue Meadows co can Association for che Accreditation of Editor FIC, Jim Bryant Laboratory Animal Care) standards prior to che Richard McManus NCI, Patricia A. Newman Perrine. Lawson will remain 3 to 4 weeks storm. We'll have to see how much it would NCHGR, Leslie Fink supervise repairs. The workers will live aboard rake to bring ic up to AAALAC's guidelines." NCNR, June Wyman Assistant Editor a 29 1/2-foot mobile home that DES rented for lnicial estimates place this cost at approximately NCRR, Polly Onderak Anne Barber NE!, Linda Huss a month. Lawson also secured from the NIH $4.5 million, he said. NHLBI, Louise Williams motor pool a 22-foot moving van, a 7-ton Urrutia thanked che first wave of volunteers NIA, Vicky Cahan dump truck,a utility trailer,and a front-end just before they left campus and wished them Staff Writer Carla Garnett NIAID, James Hadley loader. The vehicle convoy will be escorted by well on their difficultmission. NIH director NIAMS, Amy Iadarola police once it reaches Jacksonville, some 600 Dr. Bernadine Healy also expressed her concern NICHD, Carol Florance miles north of Perrine, U rruria said. "Thar's for the welfare of the animals at Perrine and the Editorial Assistant NIDCD, Gail Blatt because there's a danger of looters,particularly need for a rapid restoration of the facilities by Marilyn Berman NIDDK, Eileen Corrigan NIDR, Mary Daum in search of building supplies." NIH. chose NIEHS, Hugh J. Lee Formally known as che NIH Perrine Primate "A lot of logistical work went into this TheNIH Record reserves the righ1 to make corrections, changes, or deletions NIGMS, Wanda Warddell Center Hurricane Andrew Emergency Damage project," marveled Urrutia. "It was very well in submiued copy in conformity with NINOS, Carol Rowan Repair Task Force, the group is caking with it coordinated. They will bring the relief that is the policies of the paper and HHS. NLM, Roger L. Gilkeson virtually everything it will need for living. necessary to restore chis facility for the benefir "We've got generators, compressors, hand and of NJH." D The Record page 3 Sept. 15, 1992

NIAID Honors Sheldon Wolff, Distinguished NIH Alumnus, at Research Festival The NIH Research Festival provides an one of the most productive and respected opportunity for NIH scientists to celebrate clinical research facilities in the country. their most recent achievements and to explore His LCI initiatives in the study of fever have the implications chis work may have for the resulted in major contributions to our under­ future. standing of the mechanisms char cause fever, the A highlight of che festival is the NIH Alumni effects of fever on the host, and the role of fever Symposium. NIAID, as the coordinating in infectious, inflammatory, and immunologic institute for chis year's symposium, has entitled disorders. the program "Frontiers In Immunology and Patients with fevers of unknown origin also Infectious Diseases." The symposium will cake attracted Wolffs interest at LCI. In addition to place in Masur Auditorium on Monday, Sept. identifying the immunologic defects chat caused 21, from8:45 a.m. until noon. Ir provides the many such illnesses, he also found dramatically setting for the presentation of the 1992 NIH effective, often lifesaving, treatments for these Distinguished Alumni Award, which NIAID patients. director Dr. Anthony S. Fauci will present to In addition, work that Wolffbegan with Dr. NIAID alumnus Dr. Sheldon M. Wolff. Charles Dinarello in LCI resulted in The alumni of NIH form an elite corps of Dr. Sheldon M. Wolff groundbreaking research on interleukin-1, a scientists and physicians. Wolff not only stands fundamental and very powerful component of as a leader among that group, his accomplish­ 1960, when he joined NIAID's Laboratory of the body's immune system. ments-both at NIAID and since-serve as a Clinical Investigation (LCI), directly after Wolffis currently at Tufts University School symbol of the achievements and the goals of the completing his medical residency. Within a of Medicine in Boston, where he is serving as institute. As his contribution to the sympo­ short time, his strengths as an investigator, Endicott professor and chairman of the sium, Wolffwill discuss "Mechanisms of Hose clinician, teacher, and administrator had infused department of medicine. He maintains close Defense: Recollections on the Development of the lab with a new vigor. He subsequently ties with NIAID, and continues to garner some an Intramural Program." became NIAID clinical director and chief of of the scientific community's most prestigious Wolffsintramural tenure at NIH began in LCI, which, under his leadership, grew to be awards. D

Julius Axelrod, Nobel Laureate, To Be Honored at Symposium, Sept. 18 Dr. Julius Axelrod, who won the 1970 Nobel Johns Hopkins University; Dr. Ira B. Black, Prize for physiology or medicine while working University of Medicine and Dentistry of New at the N acional Institute of Meneal Health, will Jersey; Dr. Hans Thoenen, Max-Planck-Institute be honored at an upcoming scientific sympo­ for Psychiatry; and Dr. Leslie Iversen, Merck sium for his contributions to the field of Sharp & Dohme Research Laboratories. D neuroscience. The symposium, held on the occasion of Axelrod's 80th birthday this year, will begin at 8:30 a.m., Sept. 18 in Masur Response to DES Survey Auditorium, Bldg. 10. Axelrod began his career at the National The Division of Engineering Services' Heart Institute in 1950-wichout a Ph.D. Grounds Maintenance and Landscaping After earning his doctorate in pharmacology, he Branch's Quality Circle would like to thank the embarked on a career in neuroscience research many NIH employees who responded to their at NIMH. He has made numerous scientific Mar. 3 customer survey. The survey was sent contributions including the discovery of drug­ to 500 NIH employees requesting comments, metabolizing enzymes and the enzymes suggestions, and ideas that could help GMLB responsible for the metabolism of biogenic to provide a more functional and aesthetically amine neurotransmitters. Dr. Julius Axelrod pleasing campus. Axelrod won the Nobel Prize for his research More than 100 responses were received on involving the mechanisms by which nerve cells 70 scientists, many of whom have advanced to topics such as planting, sidewalks, grading and both remove and metabolize the neurotransmit­ prestigious positions at highly acclaimed drainage, maintenance, picnic tables, and ter norepinephrine. His discovery of the research institutions. signage. Each suggestion and/ or comment is reuptake process for certain neurotransmitters NIH director Dr. Bernadine Healy will be currencly being reviewed and an action plan has led to the development of new antidepres­ among the introductory speakers at the sympo­ will be developed based on the findings. The sant medications and other drugs to treat sium lauding Axelrod, with NIMH director Dr. plan will then serve as a guide for making mental disorders. Frederick K. Goodwin giving the opening specific improvements on campus. D His discoveries have also enabled him and remarks. other investigators to study the role of these The symposium will feature a number of Postmenopausal Volunteers Needed neurotransmitters in behavior and in psychiatric Axelrod's former postdoctoral fellows who will illnesses such as depression and schizophrenia. speak on their current work, including Dr. Women, who experienced a normal meno­ Sharing the 1970 Nobel Prize with Axelrod Joseph Coyle, Harvard Medical School; Dr. pause after age 45, and have had no menstrual were Sir Bernard Katz, University College, Jacques Glowinski, College de France; Dr. cycle within 2 years are wanted for an NICHD London, and Dr. Ulf von Euler, Karolinksa Richard J. Wurtman, Massachusetts Institute of study. The candidates should be in good Instituter, Stockholm. Technology; Dr. Roland D. Ciaranello, health, on no regular medication, and able to In addition to his pioneering research, Stanford University School of Medicine; Dr. come in for one outpatient visit to the Clinical Axelrod has mentored and trained more than Chris Felder, NIMH; Dr. Solomon H. Snyder, Center. If interested call 496-4244. D The Record page4

Sepe. 15, 1992

NIAAA (Continued from Page 1) laboratories and a clinical unit offers scientists management, as well as the extramural divisions the opportunity to formulate hypotheses in of biometry and epidemiology, basic research, mainstream of biomedical and behavioral laboratory and clinical settings and to test those and clinical and prevention research: research and, simultaneously, to expand our hypotheses in readily available clinical popula­ With the Oct. 1 reorganization, the NIAM longstanding interest in linking the two." tions. director will have offices in both Bldg. 31 and The interrelationship of genetic and environ­ "The reorganization will formalize our the Parklawn Bldg. mental factors in alcoholism etiology in part ongoing relationship with other NIH institutes NIAMalso serves as a national resource for explains NIAM's role in linking biomedical and facilitate scientific exchange-both among the collection, analysis, and dissemination of and psychosocial research. In addition, alcohol NIAM components and throughout the alcohol research findings through scientific ry Alcohol Health effects are manifest in almost eve human expanded NIH community," said Dr. Markku meetings,Research World, publications, and electronic media. organ system, and alcohol abuse affects every Linnoila, scientific director of the Division of TheAlcohol institute Alert, publishes & aspect of society. Intramural Clinical and Biological Research. a quarterly scientific journal, Consequently, it has been neither possible nor Senior investigators in the intramural program and a quarterly bulletin for desirable to study alcohol abuse and alcoholism are internationally recognized scientists in basic clinicians, as well as monographs and other ry from a single disciplina perspective. and clinical electrophysiology, brain imaging, special reports. Two hundred years after the Philadelphia molecular genetics, developmental and behav­ ETOH, a bibliographic database of more than physicians identified a "plague" of alcohol ioral pharmacology, intermediary metabolism, 75,000 records from scientific journals, problems in colonial America, an estimated 8.6 and cell membrane functioning. monographs, and conference papers, and other percent of adult Americans still meet standard Components of the intramural Laboratories of sources, and the Quick Facts electronic bulletin diagnostic criteria for alcohol abuse or alcohol­ Membrane Biochemistry and Biophysics, board of epidemiologic information are ism. Approximately 25 percent of persons Neurogenetics, Molecular and Cellular Neuro­ available to investigators worldwide. admitted to general hospital beds screen biology, and Metabolism and Molecular Future scientific emphases include studies of positively for alcohol-related conditions. Biology are located both in Bldg. 10 and at the genetic vulnerability to both alcoholism and Alcohol-related medical effects include liver Washington Ave. "Flow" Bldg. in Rockville. alcohol-related organ damage, fetal alcohol disease, pancreatitis, cardiovascular disorders, With the opening of Bldg. 49, the Laboratory syndrome, medications development, and brain and brain damage that can range from mild of Molecular and Cellular Neurobiology will be imaging in alcoholics to characterize the neurobehavioral deficits to profound dementia. moved from Rockville to the NIH campus. neurochemical bases of craving, impulsivity, Alcohol was responsible for approximately The Parklawn Bldg. on Fishers Lane in and severe memory and cognitive impairment. 107,800 deaths in 1988, of which almost Rockville houses the offices of scientific affairs, For additional information, contact the Office 19,000 (such as alcoholic liver cirrhosis) were policy analysis, international and intergovern­ of Scientific Affairs,' Scientific Communications directly attributable to alcohol. Approximately mentalNLM Toaffairs, Present and planning Exhibit and on resource Mind and BodyBranch, (301) 443-3860. 0 41,000 (due to diabetes and certain cancers) were indirectly attributable to alcohol, and more than 48,000 stemmed from injuries and "Mind and Body: Rene Descartes to William other consequences (such as motor vehicle James," an exhibit commemorating the accidents, burns, and falls) indirectly attribut­ centennial of the founding of the American able to alcohol. Psychological Association in 1892, will be on The estimated economic cost of alcohol abuse and alcoholism in the United States ranges display in the lobby of the National Library of Medicine through Dec. 15. The exhibit was from $86 billion to $116 billion each year. prepared by NLM's History of Medicine NIAM confronts these human and economic costs through an integrated program of basic Division in collaboration with Dr. Robert H. Wozniak of Bryn Mawr College. and clinical research to develop new knowledge for reducing the incidence and prevalence of The exhibit considers both aspects of the alcohol abuse, alcoholism, and associated mind/body question-the relationship of the morbidity and mortality. mind to the brain and the relationship of the NIAM's extramural research agenda includes mind to the world around us. Much of the studies of genetic predisposition to alcoholism, intellectual history of psychology as both a medical consequences, alcohol and pregnancy, scientific and a clinical enterprise has involved pharmacological and psychological-behavioral the attempt to come to grips with these two problems of mind and body. The subject is interventions for alcoholism and its effects, alcoholism treatment outcome, and individual­ traced from the first systematic account of the and environment-oriented preventive interven­ mind/body relationship in the work of Rene Descartes (1596-1650) to the culmination of Although the great philosophical distinction tions. Two large multisite, multidisciplinary between mind and body in western thought can collaborative studies of alcoholism genetics and various trends relating to the mind/body problem in the functionalism of William James be traced to the Greeks, the first systematic of patient-treatment matching are special account of the mind/body relationship was given (1842-1910). De homine focuses of the extramural program. by Rene Descartes (1596-1650). The NIH campus-based Laboratory of Among the classic works on displayLecons insur the Les Clinical Studies and other laboratories of the exhibitmaladies will du besysteme Rene nerveux Descartes' Division of Intramural Clinical and Biological (1662), Jean-MartinAn Essay Concerning Charcot's Humane Research have exemplified the institute's bench­ Understanding (1872-73), John catalog of the books on display has been issued to-bedside approach since 1983, when the Locke'sGrundzuge der physiologischen Psychologie[sic] in conjunction with the exhibit. Single copies institute opened an inpatient unit on the NIH (1689), WilhelmThe MaxPrinciples Wundt's of of this publication, which has the same title as campus, and the Clinical Center began to Psychology the exhibit, may be obtained free by writing: (1874), and William James' Chief, History of Medicine Division, National admit patients for alcoholism treatment and ry research. (1890). Libra of Medicine, Bldg. 38, Rm. 1 E21B, A booklet containing a historical essay and a The combination of well-equipped research 8600 Rockville Pike, Bethesda, MD 20894. 0 The Record page 5 Sept. I 5, 1992

STEP Unveils 30th Anniversary Program Offerings for 1992-1993

In celebration of its 30th year of providing tp make a presentation and struggled with visual role playing. training opportunities to the NIH extramural a'ids, this course is for you. The module will The popular Forum series, usually conducted community, the Staff Training in Extramural offer guidance on developing an effective in 2 or 3-hour afternoon sessions in Wilson Programs (STEP) committee recently an­ presentation using slides, overheads, graphics, Hall, offers several topics this year. One forum nounced its offerings for 1992-1993. charts, and other visual media. will explore the impact of changing technology Continuing its tradition of addressing current Module 3, "The Health of the Universities - on office dynamics; another the hiring chal­ issues and meeting training needs forextramural What's Up Doc?" is scheduled forMar. 17 and lenges of the l 990's. A new STEP approach, staff, STEP will offer a wide variety of modules 18. NIH's partners in research are facing many the informal group discussion, will address and forums as well as the popular Science for of the same challenges we are encountering in rebuttal letters and codes that bar award. After All series. Modules treat topics in depth; the l 990's as well as raking advantage of new a brief presentation on the subject by an expert, forums provide a chance for discussion of opportunities. This module will provide a participants will form small discussion groups. current issues in a short format; and, the chance to hear what our academic colleagues Finally, a forum in celebration of the 30th Science for All lectures provide health informa­ have to say about changing funding sources, anniversary will be conducted on aging issues. tion on a level rhar can be understood by rhe demographics, and priorities. Will the NIH­ Dates, times, faculty, and other details of the nonscienrist. academia relationship of the past continue in forums will be published here and promoted The programs are generally open to all the future? How does NIH affect these through flyers. No advance registration is extramural staff regardless of grade or function. institutions? How are faculty and staff faring? needed. Certain sessions are targeted to a specific This year's Science for All series, building on audience. No advance registration is required last year's programs on AIDS and hormone for forums or the Science for All lectures but replacement therapy, will again address subjects applications are necessary for participation in of increased attention. Topics are Alzheimer's modules. Applications for the first three disease, tuberculosis, breast cancer, and prostate modules described below are due by Oct. 9. cancer. The deadline for applying for the other two The new STEP catalog is available in person­ modules is Dec. 11. Application Form 2245 nel offices, the STEP office (1/252), and rhe (copies acceptable) should be completed and following locations: 3l/1B44; 38A/604; EPN/ forwarded to rhe STEP office (Bldg. 1, Rm. 505F; EPS/638; Federal/800A; Gateway/ 252) by the deadline. Be sure to read the 2N212; Solar/3Al2; Westwood/648; and instructions carefully as modules with limited NIEHS/303A. □ space use the application to determine selection. STEP falls within the auspices of the Office of Biostatistics Conference Planned Extramural Research under Ors. George An NIH conference on the applications of Galasso, James O'Donnell, and Donald _'j statistics to biomedical research will be held in Murphy. The annual program is developed by ,.·'' Lister Hill Auditorium, Bldg. 38A, on Jan. 25- an NIH-wide committee of approximately 25 26, 1993. The program will include a broad experienced extramural staffin a variety of •' range of topics covering methodologic ap­ disciplines. In addition to developing the David W Snight proaches to the diverse design and analysis issues training sessions, members conduct them along encountered by NIH statisticians. Attendance with former committee members, senior NIH These questions and more will be addressed by will be limited by the capacity of the lecture hall staff, and faculty drawn from leaders within and leaders of public and private research-oriented (approximately 150). Preregistration is highly outside NIH. academic institutions, professional organiza­ recommended. A banquet honoring those who David W. Snighr, chief of the Research tions, and senior NIH staff. introduced statistics to NIH will be held on the Contracts Branch, OD, has been appointed Module 4, "The NIH Maze: Your Fir in the evening of the 25th. To receive further infor­ chairperson of the STEP committee this year. Puzzle" continues STEP's commitment to meet mation and registration forms, contact: Biosta­ Dr. Lynn Amende of the NHLBI Review the needs of extramural staff in grades 10 and tistics Conference, c/o CONWAL Inc., 520 N. Branch is vice-chair. The program is directed below. Persons in technical, secretarial, clerical, Washington St., Suite 100, Falls Church, VA by Arlene Bowles. program support and related extramural 22046, Attn: Dina Rice, (703) 536-3200. D This year's program includes five modules, positions in those grades are encouraged to five forums, and four Science for All presenta­ check this out. Senior NIH staff will provide an Female Volunteers Needed tions covering a range of topics. They are overview of NIH extramural functions and The section on behavioral endocrinology, designed to help staff stay current, sharpen history. Personal views of extramural jobs and Biological Psychiatry Branch, NIMH, is skills, and interact to deal effectivelywith the career opportunities will be explored with plenty currently seeking female volunteers between the changing world of science administration. of rime for questions and comments from ages of 18 and 45 to participate in a 5-month Module 1, "Bioethics: Hard Choices in a New participants. This module will be held Apr. 14. study investigating the effectsof reproductive Era" starts rhe anniversary year off on Dec. 9 Module 5, "Changing Tomorrow Today: Rise hormones on brain and behavior. and 10. Ethical issues affect NIH at every rum and Shine" will be conducted on Apr. 28 and Volunteers must have regular menstrual cycles and decisions by individuals, scientists, health 29. The world and NIH are undergoing rapid with no changes in mood in relationship to care providers, insurers, employers, and the and significant change. Middle and senior level menses, be free of illnesses and not taking any government are becoming increasingly complex. NIH extramural managers are facing challenges hormones or medication on a regular basis. Extramural staff interested in case studies as well never encountered by their predecessors. How They will complete daily rating forms and will as hearing fromthe experts in this area should are they doing? What can they do better? How be asked to participate in one of several apply. can change be used to their advantage? A protocols. Payment will be in accordance with Module 2, "What's Your Point?" will be professional trainer will explore these and other the duration of visit and protocol. For informa­ offered on Jan. 14, 1993. If you have ever had issues with participants, using case studies and tion call Dr. Peter Schmidt, 496-9675. D The Record page 6

Sept. 15, 1992

Back to School: DCRT Computer Training for Fall

The new fall term of DCRT computer will offera seminar on Dec. 2. Dr. Ralph DCRT Computer Training Program are given training gets under way this month with a Nossa! will present "Physical Models of Cell without charge. To receive a published copy of packed schedule that promises to inform and Locomotion" on Dec. 9. Richard Feldmann the Computer Training Courses and Seminars enlighten course participants. All instructors will show and discuss preliminary results of a catalog-with complete dates, times, and are from DCRT unless otherwise noted. new topological model of the relation between a locations-visit the Technical Information protein and its solvent environment in his Dec. Office in Bldg. 12A, Rm. 1015, or call 496- Scientific Computing 11 seminar on prediction of protein folding, 5431. For WYLBUR users, detailed class and Kenneth Kempner will present a seminar information is available online through Scientists and other members of the research on !MACS (image management and communi­ WYLBUR's ENTER TRAINING command. community will find many of the classes useful cation systems) on Dec. 15. Laboratory analysis For assistance with registering, call the DCRT for their research and for the computer applica­ package (LAP) will be the subject of a seminar Training Program, 496-2339. To apply for tions in their laboratories. A series of SAS given by John Powell on Dec. 17. any of the classes, complete the one-page (statistical analysis system) classes is being nomination form at the back of the catalog and offered starting with "Orientation to Running Computer Technology mail or fax it (402-0537) to the Technical SAS on the Mainframe," on Sepe. 16, and again Information Office. Forms may be duplicated, on Oct. 26. Connectivity, interoperability, and A number of new computer topics reflect and those from earlier terms can still be used. distributed computing applied to flow recent trends in computing. For people who For seminars, telephone registrations are also cytometry will be the focus of a course led by are interested in writing programs on the accepted; just call the DCRT Training Pro­ Luther Barden on Oct. 8 and 9. Macintosh using C, Pascal, Assembler, Fortran, gram. Classes on sequence analysis abound chis term. or HyperCard, Ed Estes will be offering a Additional personal computing courses, On Oct. 14, Dr. Peter FitzGerald will discuss seminar on Oct. 5. DCRT's Intel Highly offered by the NIH Training Center, are the potential impact to users of the introduction Parallel Supercomputer will be featured in an described in detail in the annual NIH Training of a native Unix version of GCG, a sequence all-day presentation, "Introduction to Parallel Center Catalog and Calendar and in quarterly analysis package. Dr. Dale Graham will present Computing," on Oct. 20 by Gary R. Withers brochures published in August, December, a seminar for researchers who use the Macintosh and Scan Irwin of Intel Corporation and March, and June. See your personnel or for sequence analysis, "Using Computers to DCRT's Dr. Robert Martino. administrative office or call the NIH Training Find Possible Regulatory Elements," on Oct. For people who use personal computers for Center, 496-6211, for additional information.□ 15. This seminar includes a demonstration and presentations, John White will give "Presenta­ discussion of GCG programs on the Convex tion Graphics Strategies Using Windows 3.1" and personal computers. On Nov. 16-18, on the morning of Oct. 27. That afternoon, FitzGerald will present an introductory course, Dr. John Fletcher and Richard Shrager will give "GCG Sequence Analysis on the Convex." a new seminar on mathematical modeling with On Oct. 22, Dr. Robert Pearlstein will MATLAB and MLAB. present, "Introduction to Molecular Modeling," Features of one local area network (LAN) mail an overview of molecular modeling resources system will be discussed in a new "Microsoft available at NIH. Although this seminar will Mail" seminar by Susan Chaffee on Oct. 29. not provide instruction in the use of specific In a Dec. 1 seminar, Tom Mason will describe software packages, it will describe and compare the facility chat allows NIH users to subscribe to molecular modeling software for use on LISTSERV mailing lists or to establish their personal computers, Macintoshes, Unix own lists. LISTSERV mailing lists allow users workstations, and the Convex. to distribute information to subscribers across On Nov. 16, Jean Daugherty will provide an the country or around the world. overview of the new Scientific Computing A number of ocher courses will be offered chis Resource Center (SCRC). A lecture describing fall: the facility will be followed by a visit to the • "ENTER MAIL" on Sept. 23 and Dec. 2, SCRC during which specialists will demonstrate • "BITNET" on Sept. 24 and Dec. 3, some of the equipment available for NIH • "Intermediate PC-DOS" on Oct. 1-2 and researchers to use. Dec. 10-11, Christina Mangurian, a student working in On Nov. 19 and 20, Dr. Adrian Parsegian will • "Introduction to ISPF/PDF" on Oct. 15, NIDR's Laboratory of Developmental Biology, was lead a two-part seminar, "An Introduction to • "Networks for the Scientific Community" selected to represent the state ofMaryland in the Practical Thermodynamics Useful to the on Nov. 2, U.S. Department ofEnergy Honors Program at Laboratory Biochemist." While the title may be • "Using the Internee" on Nov. 3, Oak Ridge National Laboratoryin Oak Ridge, daunting, Parsegian's informal approach to • "LANConcepts" on Nov. 4, Tenn. She spent 2 weeks this summer working explaining the scientific principles underlying • "Network Services" on Nov. 6, with researchers in the Environmental Science common laboratory reactions (e.g., solvacion of • "NU net, LAN, Mainframe Mail Connectiv­ Division at the Oak Ridge facility. Mangurian, a proteins, allosterism, mechanisms of channel ity" on Nov. 18, Westinghouse Talent Search semifinalist, received opening) is certain to make this useful to the • "Andrew File System" on Nov. 24, and the honor forresearch she conducted with NIDR's majority of biochemists and many molecular • "Technology for Connecting Networks at Dr. JeffreyKopp on HIV-transgenic mice. The biologists. NIH-NIHnec" on Dec. I. U.S. Navy recentlyhonored her for the same work December brings a bonanza, with three new by choosing her as one of25 students in the nation scientific seminars. For those who want to Registration Information to visit laboratories at the naval base in San prepare schematic diagrams and other drawings Diego. A 1992 graduate of Walt Whitman High to "polish up" output from graphing, statistics, The fall term includes more than 70 courses School in Bethesda, she will attend Reed College in sequence analysis, and ocher programs, Graham and seminars, and, as always, all classes in the Portland, Ore., this fall. The Record page 7 Sept. 15, 1992

Fire Prevention Week To Be Observed at NIH, Oct. 4-1 Registration Deadline Nears for NIGMS o Biomolecular Engineering Conference

Fire Prevention Week, Oct. 4-10, commemo­ • Wednesday, Oct. 7, 10 a.m.-2 p.m.-Bldg. rates the "Grear Chicago Fire," which occurred 38A, Lobby; As is the case in many fields of science, the in October 1871. In that tragic fire, more rhan • Thursday, Oct. 8, 10 a.m.-2 p.m.-Bldg. division between biology and biochemical 250 people lost their lives and property damage 31A, Lobby; engineering is blurring, and at the intersection exceeded $168 million. The technology and • Friday, Oct. 9, 10 a.m.-2 p.m.-Bldg. 10, of these fields a new one is developing. The expertise of the firefighting profession has ACRF Lobby; and 11 a.m.-1 p.m.-Bldg. 10, emerging field, known as biomolecular engi­ changed dramatically since that era; however, Outside the B 1 Level Cafeteria (NIH Fire neering, is characterized by the selection and more than 5,000 Americans still die each year in Department vehicles will be on display, study of model systems with obvious techno­ fires, 80 percent of which occur in rhe home. weather permitting). logical relevance, emphasis on molecular To observe Fire Prevention Week here at "Everyone should take advantage of the useful phenomena, synthesis of information from NIH, the Emergency Management Branch of information and expertise available at these different disciplines, and quantitative analysis. the Division of Safery will provide information displays and meet the staff of the fire prevention NIGMS will sponsor a meeting on Dec. 7 and regarding fire safety ar several locations around and fire suppression components here on 8 to highlight the scientific impact of the reservation. Brochures relating to fire safery campus. The advice and guidance provided by biomolecular engineering, describe the research m rhe home, at work and when traveling will be the EMB staff can help make your home and accomplishments and opportunities in this available; video tapes will be shown; and various workplace foe-safe," says Michael L. Spillane, field, discuss its relevance to the NIH mission, deputy chief, EMB, and coordinator for this and promote interaction between the biochemi­ year'sBrittle Fire Bones Prevention Meeting, Week Sept.activities. 23-25 D cal engineering and biomedical research communities. Researchers from around the world will Entitled "Research Opportunities in convene Sept. 23 through 25 at the Bethesda Biomolecular Engineering: The Interface Marriott Hotel to discuss the research and Between Chemical Engineering and Biology," treatment of osteogenesis imperfecta (OI), a the meeting is being held at the Omni genetic disorder in which affected individuals Shoreham Hotel in Washington, D.C. Speak­ have brittle bones susceptible to fracture after ers will cover the following biological areas in even mild injuries. which chemical engineers can make important The conference, called "Frontiers in Rehabili­ contributions: the production of recombinant tation Medicine: Osreogenesis Imperfecta," will proteins, metabolic engineering, cell engineer­ be held at 5151 Pooks Hill Rd. Sponsors of the ing, molecular biosepararions, and biocaralysis. conference are the National Center for Medical The meeting will also feature approximately 40 Rehabilitation Research of the National invited poster presentations. Institute of Child Health and Human Develop­ The conference is being cochaired by Dr. ment (NICHD) and the National Institute of George Georgiou of the University of Texas, Arthritis and Musculoskeletal and Skin Diseases. Austin, and Dr. Irene Glowinski of NIGMS. "The purpose of the meeting is to communi­ Session chairs include Ors. Jonathan King of cate the latest advances in basic research to MIT; James Swartz of Genentech, Inc.; Michael clinicians and medical rehabilitation profession­ Shuler of Cornell University; Janet Westpheling als and to stimulate new, interdisciplinary of the Universiry of Georgia; Douglas investigations that will lead to functional Lauffenburger of the Universiry of Illinois; improvement of people with OI," said confer­ Patrick Aebischer of Brown University; Richard types of fire protection equipment will be ence cochair Dr. Joan Marini, head of the Wilson of the University of Houston; Richard displayed. Knowledgeable staffwill be present section on connective tissue disorders of Burgess of the University of Wisconsin; Robert to answer any questions you may have. This is NICHD's Human Genetics Branch. The M. Kelly of North Carolina State University; an excellent opportunity to learn more about meeting will also be cochaired by Dr. Lynn and George M. Whitesides of Harvard Univer­ the critical techniques and equipment which Gerber, chief of the Department of Rehabilita­ sity. may save your life, the lives of your family and tion, NIH Clinical Center, and Dr. Peter Byers, To be placed on a mailing list to receive your coworkers and protect your valuable professor of pathology at the University of information about and registration materials for property from the ravages of fire. Washington. this meeting, call Nancy Gaskins of Social & Highlighted in rhe displays will be the OI results from a defect in one of the genes Scientific Systems, (301) 986-4870, by Oct. 1. presentation of a new video, "Evacuation-Your that codes for type I collagen, the major To learn more about the scientific content of Safe Escape," which was produced this year by structural protein of bone and skin. In addition the meeting, call Glowinski, (301) 496-7125. D the Emergency Management Branch to enhance to brittle, easily broken bones, 01 patients may Chamber Players Concert, Sept. 24 emergency evacuation techniques at NIH have growth deficiency, scoliosis (a curvature of facilities. Proper procedures for assisting the spine), bowed legs, heart abnormalities, persons with disabilities are demonstrated in hearing loss, and dislocated joints. OI patients The NIH Chamber Players will present guest may also bruise easily and sweat excessively. OI rhis film. A raffle will also be held on Friday artist Midge Carlton, flute, with Carl Banner, afternoon in the ACRF Lobby with fire occurs in from 1 in 20,00 to 1 in 30,000 people. piano, in a program of flute and piano music on Speakers will address such topics as the extinguishers, smoke detectors, and other home Thursday, Sept. 24, from 11 :30 a.m. to 12:30 pathology and molecular biology of O I, its fire safery devices being given as prizes. Raffle p.m. in the 14th floor assembly hall, Bldg. 1 O. endocrinologic and neurologic complications, rickets are available at the display each day. You The program will feature the new Petroff grand and its treatments. do not have to be present at the drawing to win. piano recently acquired by the patient activities Those wishing to attend should contact Displays will be at the following locations: department, and will include sonatas of Bach, • Tuesday, Oct. 6, 10 a.m.-2 p.m.-Bldg. 35, conference organizer Dr. Danuta Krotoski at Poulenc, Faure, and Prokofiev. D Lobby; 402-2242. D The Record page 8 Sept. 15, 1992

CONTE BLDG. (Continued from Page 1)

1993, preceded by a dedication ceremony co cake place Sepe. 17 for the 8-scory facility numbered Bldg. 49. By lace spring of 1993, employees from NICHD, NIMH, NINDS, NIAAA, NEI, NIDR and NIA will occupy che new building, hailing from space both on campus (primarily Bldgs. 6, 9, 10, 30, 36 and 37) and off (Park, Flow and DANAC Bldgs.) Those workers, and NIH'ers who tour the facility during a month-long open house (0cc. 1-31, call 402-4061 co schedule a visit), will find an "intelligent" building chat is essentially two buildings in one-an animal facility and a laboratory/office facility. The building's intelligence, explains project officer Stephen Hagan, a DCB/DES architect, arises from the face chat it has been wired for virtually any combination of local area com­ puter network (LAN) as well as telecommunica­ DES carpenter BillFarrell works in one ofthe conference areas/solaria that grace the front of Bldg. 49. tions (phones, faxes and modems). Additional Out the window is the excavation forBldg. 29B, a construction crane, and Bldg. 36. security measures (cardkey entrances, closed circuit television monitoring) add to an aura of high-technology. features as epoxy wall and floor coverings, for the Silvio 0. Conte Building, and, perhaps in A DCB/DES team whose key members easy cleaning and maintenance, and a special che future, a clock in che archway of the included Hagan; Ernest Lunsford, assistant ventilation system. Metal rails buffer walls and building's top-floor pediment. DCB chief; Cyrena Simons, science and design corners from collisions with cages and carts. A design and construction oversight commit- coordinator; and Frank Kudak, architect, Animal elevators are segregated according co tee consisting of representatives from the user guided the structure to completion, incorporat­ whether they are clean or dirty. A large institutes has worked closely with DES staff to ing elements they hope will lead to optimum cagewashing facility in the basement can determine occupancy schedules and amenities. science. accommodate both large and small animal Hagan amibuces a good deal of the project's For instance, on the seven floors that include cages. success to management guidance provided by laboratory space (divisible into some 200 Ocher special features of the building are: a 4- Dr. Richard Wyatt (program manager) and Dr. "modules"), there are two different kinds of story staircase atrium that building designers Cherie Fisk (program project manager), who are corridors: che utility service and delivery created as an "interaction" space as scientists members of that oversight committee. The corridors allow maintenance staff direct access walk from floor co floor; and conference space oversight committee was originally chaired by to pipes and utilities and give researchers access on che first floor chat can be subdivided into the lace Dr. Ernst Freese, NINDS, and is now to lab support rooms; there are also separate two rooms seating some 100-120 people, with chaired by Dr. Arthur Levine, NICHD "people" corridors where scientists will pursue projection screens and TV monitors provided in their labors unobstructed by freezers and file each half. The building will also host a small­ cabinets. scale art program "similar co the program in che "There won't be any equipment in the people Clinical Center," Kudak said. General art will corridors, so veteran NIH scientists probably be shown in the public pares of the building; won't recognize it at first as lab space," jokes the lab section will host chiefly science-related Kudak. "This facility will be an upgrade in posters, he said. Also of interest are large, quality for everybody who occupies ic." pendant lamps at the front of the building, a Photos: Bill Branson The upper stories of che building are divided sign on che building's west side designating ic into zones, explains Hagan, who describes che facility in layers from front to back. At the front, facing south, are offices. The five upper floors include at their center a solarium/ conference room offering views of south campus. Laboratories occupy the middle "slice" in the building. Centered in this lab section is a break room/interaction area with a kitchenette including refrigerator, microwave and vending machines. The next zone features procedure rooms and the last zone is animal holding space. Chief among che many unique features of the Farrell puts a level to the edge ofa glass partition 250,000-square-fooc facility is its adherence co that shields the break area from laboratory space. The solariaon the south sideof Bldg. 4:)offer standards sec by the American Association for The semicircular enclosure allows a measure of refreshing views ofsouth campus as well as meeting the Accreditation of Laboratory Animal Care privacy to workers using the kitchenette. space for institute personnel. (AAALAC). The animal part of che building includes such The Record page 9 Sepe. 15, 1992

DCRT Lecture Explores Computer Emulation of Mental Functions

The Laboratory of Statistical and Mathemati­ cal Methodology, DCRT, will sponsor a lecture tided "The Promise of Neural Networks in Emulating Mental Function." Prof. Daniel S. Levine of the mathematics department at the University of Texas, Arlington, will speak in Wilson Hall, Bldg. !, 2:30-4 p.m. on Friday, Sept. 18. Artificial neural networks are used to compute results by training and adapting a computer system until it responds correccly to numerous examples. Different applications, such as pattern classification, robotic control, and knowledge representation, involve different types of networks, but all may use similar types of modular organization. The computer system architectures are loosely modeled on biological neural networks. A substantial part of current DES workers Brad Brown (l) and Bill Strine walk in the 4-story staircase atrium, which offers views of artificial neural network research is directed Bldg. 10 and the north side ofcampus. toward increased understanding of mental and neurological functions in animals and humans. Reservations are not necessary to attend the scientific director. assignments throughout the building. Final lecture. For more information, call 496- There is also a lab users' group, an animal interior construction of the Conte Bldg. was 6039 .D users' group, an NICHD-led lab management completed one floor at a time, and phased group and an NEI-led central animal facility occupancy will follow the same schedule, said group to help manage the complex. Hagan. "Generally, institutes are arranged by Hagan also said, "DES's maintenance staff floor," Kutlak added. The top two floors house has been pivotal in bringing the project online. NICHD programs, NIAAA is on floor 4 and Pete Sweeney, the Conte Bldg. engineer, Jim shares floor 3 with NINOS and NIA; NINDS O'Shea and Art Bonnet provided support and and NEI share floor 2, and NIMH shares the guidance throughout the crucial commission­ first floor with NIDR; NIMH is sole occupant ing phase of the project. From the Division of of the BI level. Procurement, Millicent Warford, John Carr Parking needs for 49 will be answered by a and John Foley also made a tremendous effort sister project to the Conte Bldg.-multi-level in executing our contracts." parking facility 8, which will be located just Kuclak says a large computer database south of 49 and should be complete by next contains all room, equipment and furniture summer.

NIA acting director Dr. Gene D. Cohen has just won a National Association of Government Communicators Blue Pencil Award for his feature article, "The Famous Case from London, December, 1843-The Rest of the Story. Itwas published at Christmas in the as "Depression Is a Dickens of a Problem," "an apt title fora piece that makesSt. Louis the case Post-Dispatch for Scrooge as a depressed old person who undergoes some dreamwork and emerges happy again. Cohen is a geropsychiatrist who, in addition to NIA duties, has for20 years volunteered his time each week as a primary care physician for patients at Regency House, a senior citizen residence in Washington, D. He is also editor-in-chief ofa new journal, the whichC. debuts in December. His editorial forthe inauguralAmerican issue Journal willreportedly of Geriatric discuss Psychiatry, the modern­ Brown and Strine ofDES make sure the 49 maintenance corridors are properlyfitted out. Pipes at right day diagnosis ofdepression and the Famous Case bring water and lab gases to each floor, and are easily maintained. from London, December 1843. The Record page 10

Sept. 15, 1992

NCRR's Whitney Named Deputy Surgeon General Mylander Named Public Affairs Chief Maureen Mylander has been appointed public Surgeon General Antonia C.Novello has affairs officer and director of the Office of announced the appointment of Dr. Robert A. Science and Health Reporrs at theNational Whitney, Jr., as deputy surgeon general, Center for Research Resources. She will direct a effective Sept. 1. Whitney was the first director comprehensive public affairs program designed of theNational Center for Research Resources, to acquaint general and scientificaudiences with formed early in 1990 by a merger of theNIH the activities and accomplishments ofNCRR. Division of Research Resources (DRR) and Mylander formerly served as a writer-editor in Division of Research Services (DRS). He had theNIH Office of Communications. There she directed DRS since 1984 and became acting specialized in health communications planning, director of DRR in late 1988. publication production, and communicating During the same period, Whitney also served health information to consumers. Among other as director of the NIH Office of Animal Care projects, she initiated NIH Hea!thfine, a and Use, established in 1987, and chaired the consumer health information service for mass PHS interagency research animal committee, circulation magazines and newspapers that the focal point for federal agencies' discussion reaches millions of readers nationwide. of issues involving animals needed for research Mylander has devoted her career to writing and testing, especially their care, use, and about health for the layperson. Prior to coming conservation. Dr. Robert A. Whitney,Jr. toNIH in 1978, she was ghostwriter for the late He is an assistant surgeon general in the PHS Dr. Michael Halberstam's health advice Commissioned Corps and served as the corps' tory Animal Medicine and is currently its columns forthe New York Times Special chief veterinary officer 1984-1989. president. Whitney transferred to the corps andNIH in He has also served as president of the Ameri­ 1971 from the U.S. Army Veterinary Corps, can Association of Laboratory Animal Science, where he had directed its postdoctoral training chairman of the board of directors of the program in laboratory animal medicine and Commissioned Officers Association, member of v sered as a consultant to the Army Surgeon the House of Delegates of the American General on that specialty. He commanded a Veterinary Medical Association, and president veterinary medical detachment in South of the District of Columbia Veterinary Medical Vietnam during 1970-71. Association. At NIH, after brief service as a special projects Whitney's many honors include the PHS officer in the DRR Animal Resources Program, Surgeon General's Exemplary Service Medal, he became chief of the Veterinary Resources the Department of the Army Legion of Merit, Branch, DRS, and served until becoming DRS Distinguished Alumnus Awards from Okla­ director. homa State University School of Veterinary Whitney received his D.V.M. in 1959 from Medicine and Ohio State Universiry College of Oklahoma State University School of Veteri­ Veterinary Medicine, the Charles River Prize of nary Medicine and his M.S. (pharmacology) the American Veterinary Medical Association, from Ohio State University in 1965. He is a and the Karl F. Meyer Award of the American diplomate of the American College of Labora- Veterinary Epidemiology Society. 0

Maureen Mylander Features Syndicate. She has written scores of health articles for national magazines and is author of five books, including The Healthy Male: A Comprehensive Health Guide forMen (And the Women Who Care About Them) and The Great American Stomach Book. Her latest book, coauthored with Dr. Patch Adams, who founded the Gesundheit Institute, is about a health care community designed as a model for healing the U.S. health care system. Gesundheit! is scheduled forpublication this fall. Mylander has won many awards for her writing, and in 1990 received the Toastmasters International Communication Achievement Award from theNIH Toastmasters Club. 0 Judo Club Resumes Classes The NIH Judo Club will hold its fall begin­ ners classes on Tuesday and Thursday evenings NIAID director Dr. Anthony S. Fauci (c) recently honored nine employees with NIH Merit Awards to from 6: 15 to 7 :30 starting Tuesday, Sept. 29 at recognize their leadership, competence and creativity. The recipients are (from l, seated) Peter Gilbert and the Malone Judo Center, Bldg. 31. The cost for Dr. Phillip Murphy. Standing are (front,from l) Genevieve Daggett and Lai Tan. At rear are (from l) 8 weeks is $35. For further information, Claire W Hannahan, Rosemary McCabe-Hamil, Michael Crumly, Dr. Guido Poli and Dr. Susana contact Stephanie Harrison, 496-9490. 0 Serrate-Sztein. The Record page 11 Sept. I 5, 1992

Siegel Heads New NLM Office Class on Fundamentals of Extramural NIH Offered

Dr. Elliot R. Siegel has been namedNLM The Office of Health Scientist Administrator HSADP office receives the vendor's copy of the associate director for health information Development Programs (HSADP) will be application by the deadline date. Applications programs development. presenting an NIH orientation course titled received after the deadline will be returned The newly created Office of Health Informa­ "Fundamentals of NIH Extramural Activities" without further consideration. Each applicant tion Programs Development, located within the on Jan. 4-5, 1993, in Bldg. 1, Wilson Hall. The will be informed of the decision concerning his/ Office of the Director, contains three units: the course starts at 8:30 a.m. Jan. 4 and concludes her application. No one will be admitted to the Office of Outreach Development, the Office of at 5 p.m. on Jan. 5, with registration at 8 a.m. course without the memo of selection signed by Planning and Analysis, and the Office of each day. the codirectors. International Programs. Siegel and his staff will The course will include an overview of the Questions about this course may be directed bring together representatives of various Library types of award mechanisms, the grant referral to Susan O'Brien, 496-1736. D programs-each of whom may be concerned and review processes, program administration, with a different aspect of an information and the fiscal management of grants. product, service, or emerging technology-so The number of participants will be limited to that all can work more effectively toward approximately 60 people. Priority will be given commonNLM goals. to program and review staff at all grade levels Examples of current activities falling under who are new (6-12 months) to extramural NIH. the scope of the new office include outreach Course applicants (including those who are programs targeted towards the needs of health PHS Commissioned Officers)are to submit an professionals serving rural and inner city HHS-350 form (Training, Nomination and Authorization) through appropriate ICD channels to the HSA Development Programs Office (Bldg. 31, Rm. 5B35). In item 10, please list your complete office address, not your home address; item 14 - "no cost"; item 18, Send Vendor's Copy to: HSA Development Dr. Judah Folkman (r), chairman ofDRG's Programs Office, Bldg. 31, Rm. 5B35; item 20 pathologyA study section and professorof anatomy A-"8", B - "8", C - "l", D - "NIA"; be specific and cellular biology at Harvard Medical School, in items 16 and 17 and indicate how long you receives the Christopher Columbus Discovery have been in the NIH extramural area; item 21 Award forExcellence in Biomedical Research from - "NIA" and item 22 - "9998". All othere Dr. Louis W Sullivan, HHS secretary. Folkman instructions are on the back of HHS-350.e received five awards in 1992: the 3M Life To be considered, applications must be Sciences Award, Federation ofAmerican Societies received in the HSADP office no later than forExperimental Biology; the WolfFoundation close of business,Nov. 20. Submitting an Prize in Medicine, Israel; the Distinguished application to personnel, no matter how early, LifetimeAchievement Award, World Congress on does not assure its reaching the HSADP office. Cell and Tissue Culture; and the Mike Hogg Dr. Elliot R. Siegel It is the applicant's responsibility to see that the Award, University of Texas, M.D. Anderson Cancer Center; and the DiscoveryAward. populations; long-range planning related to toxicological and environmental health infor­ Mediclneforthe Public LectureSerles Begins in October mation dissemination; and programs aimed at expanding the use ofNLM services in other Ovarian cancer, cystic fibrosis, and Gaucher and Vascular Diseases, NHLBI. countries (as well as enlarging the extent to disease are just a fe w of the issues that will be On Nov. 10, Dr. Sten Vermund, chief of which international contributions are incorpo­ covered in the 1992 Medicine for the Public NIAID's Vaccine Trials and Epidemiology rated into the library's collections and data­ lecture series sponsored by the Clinical Center. Branch, talks about "Sexual Transmission of bases). The lectures, which are free and open to the AIDS: Are You at Risk?" He will give an Siegel received his B.A. in psychology in 1964 public, are held on Tuesdays at 7 p.m. in overview of the AIDS/HIV epidemic and the from Brooklyn College, CUNY; his M.A. in Masur Auditorium. methods of transmission, includinghetero­ psychology from Michigan State University in The lecture series, now in its 16th year, opens sexual contact, 1966, and his Ph.D. in communication in 1969 on Oct. 13 with a look at "Ovarian Cancer: On Nov. 17, Dr. Ronald Crystal will discuss .··. the promising newareas of research in treating (also from Michigan State). He began his Current Treatment Options." Dr. Eddie Reed, "Cystic Fibrosis," a fatal, inherited lung disease. career at NIH in 1976 as a research scientist head of the medicalovarian section ofNCI's Crystal, chief ofNHLBl's Pulmonary Branch, with NLM's Lister Hill Center, where he Medicine Branch, will discuss the incidence of led a team of researchers who investi ted the coordinated the development of the hepatitis this disease and itsvarious stages, aswell as ga use ofa genetically engineered drug to control database, an early example of electronic how it is diagnosed and treated, including cystic fibrosis. knowledge-based information systems for surgery and the new drug taxol. The 1992 series closes on Nov. 24 with Dr. physicians. In 1982 he was appointed special On Oct. 20, Dr. Florence Haseltine, director Norman Barton, chief of the clinical investi assistant for operations research, where he ofthe Center forPopulation Research, ga­ NICHD, will review the latest research on tions section, Developmental and Metabolic designed and implemented evaluation studies of "Menopause." Neurology Branch, NINOS, discussing new technologies and library systems. In 1987, On Oct. 27, Dr. Basil Rifkind willdiscuss "Gaucher Disease: Restoring Health with Siegel became NLM assistant director for "Toward a Healthy Heart: A Cholesterol Enzyme Replacement." planning and evaluation, and managed the For more information on specific topics or completion ofNLM's first long-range plan. D Update." Rifkind is chief ofthe Lipid Metabo­ lism-Atherogenesis Branch, Division ofHeart speakers, call 496-2563. The Record page 12

Sept. I 5, I 992

NIAMS Employees Honored at Annual Awards Ceremony Dr. Peter M. Steinert Dr. Lawrence E. Shulman, NIAMS director, Chief, Laboratory of Skin Biology hosted the annual awards ceremony of the For establishing a highly productive research program in skin National Institute of Arthritis and Musculoskel­ biology within the NIAMS. etal and Skin Diseases recencly. Among the employees honored were the following: Diane M. Watson Grants Management Officer, Extramural PHS Recognition Award Program For exemplary leadership in representing the NIH and the Dr. Stephen L. Gordon NIAMS Grant Management Policies to the government and Chief, Musculoskelecal Diseases Branch to the community at large. For outstanding service on an ad hoc fluoride committee for the Public Health Service. Equal Employment Opportunity Special Achievement Award NIH Director's Award Nancy S. Middendorf Carolyn G. McHale Secretary to the Deputy Director Chief, Scientific Information and Data Systems For her consistently high level of sensitivity to employees with Branch Dr. Lawrence E. Shulman, NIAMSdirector, special needs through counseling, careful instruction, For extraordinary skill, leadership, and dedication in presents the Equal OpportunitySpecial Achieve­ guidance, and demonstration. establishing comprehensive, high-quality data management ment Award to NancyS. Middendorf systems forboth the NIAMSand the NIH. In addition to these awards, NIAMS employ­ ees were presented with quality step increases, NIH Merit Award Marsha G. Hennings individual and group cash awards, employee-of­ Dr. Julia B. Freeman Administrative Officer, Intramural Research the-month awards, and length-of-service Centers Program Director and Director for Program awards. NIAMS keyworkers for the Combined Research on Women's and Minorities' Health For meritorious achievement in establishing the administra- Fe

Satellite Parking and Shuttles Offered During Construction ForNIH'ers who use the overflow lots, two By Carla Garnett new, nonsrop shuttle bus routes will be added for transportation between the lots and build­ Beginning Oct. l, parking on campus will MONTROSE RD. ings I0, 3 IA and 38A on campus. The shuttle undergo a few dramatic changes due to con­ will run every I 0-15 minutes during the a.m. struction of phase I of the Natcher Bldg. on the and p.m. rush periods and every 20 minutes southeast corner ofNIH's property. Phase I during nonrush hours. Service will be provided will include a 1,000-seat auditorium, a nine­ weekdays from 7:30 a.m. to 7 p.m. room conference center, and 450 underground 'Through the transportation management and 35 surface parking slots. plan supported by the National Capital Parking lots 16D, E, F and G, adjacent to Planning Council and the Maryland National Stone House and the Metro station, are Capital Park and Planning Commission, NIH scheduled to be closed by the first of October. has agreed to maintain the half parking space Lot 16C was closed last Tuesday to make ready per employee ratio," said 0. W. Sweat, DSO forNIH's Open House. In total, an estimated ■ GROSVENOR METRO director, explaining why, contrary to sugges­ 700 parking spaces will be eliminated by the tions from many employees,NIH cannot construction scheduled to begin Oct. 1; a designate any more on-campus parking. formal groundbreaking ceremony for the "Actually," he continued, "Montgomery building was held last Friday, Sept. 11. Counry officials would prefer 0.4 space per The NIH Employee Transportation Services employee but we have agreed not to exceed the Office in the Division of Security Operations ;, 0.5 rat10. has arranged for three satellite and overflow Sweat also pointed out that NIH is much parking facilities to be available for the antici­ more fortunate than other government agencies, pated overflow. The two overflow lots-one which have an average of one slot for every 18 north of campus at Mid-Pike Plaza (Montrose Cl workers. For example, he said, the Justice Rd. and Rockville Pk.) and one south in 0 Department has a ratio of one parking space for downrown Bethesda at Bethesda Ave. and every 45 employees. Arlington Rd.-will provide about 650 spaces. \ "The answer in easing parking atNIH," Sweat The third parking area, a satellite lot at Shady concluded, "is for employees to utilize the Grove Metro Station, will be operated in Employee Transportation Services Office here, conjunction with the NIH TRANSHARE which has an extensive database for carpools, Program. TRANSHARE is a supplemented, vanpools and public transportation in the During campus construction, employees will have metropolitan area." access to the Mid-Pike Plaza parking lot. For more information about TRANSHARE, the RidefindersNetwork, or about the availabil­ public transportation program for government iry of satellite and overflow parking, call ETSO, employees; participants are required to ex­ 402-RIDE. For more information on Natcher change their NIH parking stickers and hangers Bldg. construction, call the Division of Engi­ for special Shady Grove parking permits. neering Services project officer, 496-2344. 0

-� �- ·- The National Institute of General Medical Scienc�s recently held its annual awards ceremony honoring NIGMS employees fortheir outstanding contrtbutwns to the institute throughout the year. Pictured (from Garage 57, in downtown Bethesda, is one oftwo 0 are Thomas Boyce, InformationResources Management; Rossie Fitzgerald, Grants Operations; Martha facilities that will provide overflow parking slots Shanahan, Grants Management; and Dr. Ruth L. Kirschstein, NIGMS director. Boyce, Fitzgerald, and for NJH'ers during Natcher Bldg. Construction. Shanahan received the NIH Award ofMerit, the highest award given by an !CD director. The Record page 14

Sepr. 15, 1992

Training Center Delivers Diversity for 1993 NIDR's William Driscoll Retires NIH Record

The last presented information being developed. Look for flyers advertising Dr. William Driscoll retired recently afrer 30 about the diversity of training programs and this new course during the first quarter. years in the Public Health Service-the last 21 services available to managers and their employ­ The NIH Training Center and the Personal of them at the National Institute of Dental ees from the NIH Training Center. Highlights Computing Branch are also collaborating to Research. He most recently served as chief of of offerings are described below. open a second User Resource Center located at the disease prevention section in the institute's Administrative Systems-Look for the new, Executive Plaza South. Look for the grand Epidemiology and Oral Disease Prevention hands-on "Introduction to NIH Property opening early in 1993. Program. Management" course, designed to give NIH Career Development-The popular series of During his PHS career, Driscoll became an personnel engaged in property management five Career Planning Workshops, launched in international expert on the epidemiology of functions good working knowledge of NIH FY 1992, will continue in the second and third dental caries (tooth decay), the relationship property management policies and procedures. quarters of FY 1993. Topics include: "Career between fluoride and caries prevention, and A Foreign Travel course follows the model of Assessment and Planning," "NIH Careers - methods for delivering fluoride and measuring Domestic Travel training and offers both Finding the Best One for You," "NIH SF-171 its efficacy. He wrote numerous articles and lecture and hands-on instruction on entering and KSA's Preparation," "Networking and foreign travel orders and vouchers through the Interviewing Skills," and "Projecting a Profes­ administrative database. sional Image." Office Operations-Need to update your The NIH STRIDE Program which prepares basic math skills? "Refreshing Basic Math selected participants with on-the-job and Skills" is a new, 1-day course designed to make academic training, will be announced in everyday math easy and practical. Employees February 1993. Later on, in May, the Career will develop interpersonal skills by taking Curricula program will be announced. The "Thriving in Place/Striving forMore" (a former Training and Development Services Program, STEP module), which features on-the-job which assists NIH employees in nonprofessional situations for working together in teams and series to prepare for advancement in their networking. current positions, is an ongoing career develop­ Supervisory and Management Development­ ment service. NIH supervisors and managers now have access Look for the NIH Management Intern and to a full program of courses in managing the OPM Presidential Management Intern Dr. William Driscoll employee performance, communicating Program announcements early in 1993. Both effectively, and planning and managing programs provide opportunities for outstanding resources. New courses include "Time and individuals to begin careers leading to respon­ Attendance for Leave-Approving Officials," sible management positions at NIH. Note: All position papers that were instrumental in the "Performance Appraisal Workshop," "Inter­ of the Career Development Programs are development of policy for the use of dietary viewing Skills for Supervisors," "Establishing described in detail in the FY 1993 catalog. fluoride supplements. Meaningful Performance Standards," and Scientific and Medical-Courses offered in Driscoll says he feels fortunate to have been "Sexual Harassment in the Workplace." this category include: "Using Animals in involved in every aspect of research, from Consult the catalog for the new Middle Intramural Research: Guidelines for Investiga­ conception and design of study protocols to Management Development Program overview, tors," "Hands-On Animal Workshop: Rodent analysis of the results. From the mid-l 960's to which describes an expanded core course Techniques," "How to Write and Publish the mid-1980' s, he directed a series of studies (developed from an NIH Training Center study Scientific Papers," "Scientific and Medical that looked at different approaches for deliver­ of key NIH managerial competencies) and other Editing," the "Medical Terminology" series, ing fluoride to young children in significant courses in this curriculum. Also and "Ethical Issues in Managing Research." nonfluoridated communities-the group most outlined are consulting services including Special Interest-The NIH Training Center is vulnerable to tooth decay. He found that the program development and the facilitation of pleased to offer a variety of special interest combined use of fluoride mouth rinses and ICD decisionmaking, team development, and courses including "Appropriation Law Semi­ tablets in a classroom setting under teacher total quality programs that can be conducted nar," "American Sign Language," "Break the supervision was a highly effective preventive off-site or in the workplace. Smoking Habit," "For the Culturally Diverse regimen. Personal Computing and Networking-In FY Workforce: Speaking Effective English," and Although Driscoll says he will miss the 1993, the NIH Training Center, in cooperation "Mid-Career Financial Planning." Employees excitement of NIDR research, he plans to with the Personal Computing Branch, DCRT, who anticipate retiring in the next 3 years continue his involvement in oral health research will offer upgraded versions of some of your should enroll in the "Retirement Planning through consulting work. He leaves the favorite database, spreadsheet, and word Seminar." institute with a feeling of accomplishment, ready now to spend more time on his off-duty processing application courses for PC and Custom Tailoring-Keep in mind that Macintosh computers. In addition, the custom-tailored training can readily be arranged passion, driving high-performance sports cars. Training Center will offer training on new to meet specific ICD needs. For example, the Driscoll raced a Datsun 280Z from 1975 to 1984, winning several local and regional software packages such as KaleidaGraph and center can custom-design courses such as Quark Express for the Mac and New Windows "Proofreading Techniques" and "Writing championships. He now owns a 1972 Pantera applications including WordPerfect, Excel, and Fundamentals" for support staff, in addition to and a 1985 Corvette that he drives in high Pagemaker. A course on PC/GENE, a software new and traditional topics in management, speed track events. And while some collectible­ car owners rarely drive their cars, trying to keep application package used by research scientists, supervision, and personal computing. is scheduled for February 1993. Look for For more information, consult the FY 1993 them as close to showroom condition as details in the second quarter personal comput­ catalog and first quarter brochures or call the possible, Driscoll says his idea of heaven is to ing brochure. NIH Training Center, 496-6211. 0 hop into his yellow Pantera and cruise a country An MS Mail networking course is currently road on a summer day-an avocation he will pursue with relish.-Peggy Buckler 0 The Record page 15 Sept. 15, 1992

r1il!§ TRAINING TIPS Howard J. Hoffman To Direct NIDCD Branch "g/1) J.

Howard Hoffmanrecently joined the mathematical statistician. He became chief of The NIH Training Center, Division of NIDCD staff as chief of the Epidemiology, the Biometry Branch in 1981 and in 1989 Personnel Management, offers the following Statistics and Data System Branch. became special assistant for infant mortality courses:Courses and Programs Starting Dates He received his bachelor of science in statistics research in the Division of Epidemiology, from Stanford University in 1966. In 1968, he Statistics and Prevention Research. Management and Supervisory 496-6371 received his master's of arcs in statistics from Hoffman has received many honors and Efficient Reading for Professionals 10/13 awards throughout his career, including the Using Animals in Intramural Research: PHS Special Recognition Award. He also has Guidelines for Investigators 10/22 Voice for Success: Power Communication 10/26 published nearly 100 articles, chapters and Effective Presentation Skills 10/26 books. His principal research interest has For the Culturally Diverse Workforce: concerned disorders of childhood, particularly Speaking Effective English (Basic) 10/27 sudden infant death syndrome. For the Culturally Diverse Workforce: The Epidemiology, Statistics and Data System Speaking Effective English (Advanced) 10/27 Branch was recently established within the Time I Attendance for Leave Approving Officials 10/28 How to Write and Publish Scientific Papers 10/29 Office of the Director, NIDCD, to conduct Working With Personal Differences: epidemiologic studies relating to deafness and MBTI: I for Managers 11/2 ocher communication disorders, including hearing, balance, smell, taste, voice, speech and OfficeOperations and Administrative language. 0 Systems Training 496-6211 Nonsmoking Females Sought Basic Time and Attendance 10/22 Domestic Travel 10/26-10/29 Property Management Information System 10/30 Delegated Acquisition Training Program 10/2 Working With Personal Differences: The Uniformed Services University of the M BTI: I for Technical and Support Staff 11/9 Health Sciences' department of medical Federal Supply Schedule 11118 psychology is seeking healchy, nonsmoking females ages 18-45 to participate in a women's Special Courses 496-6211 Howard j. Hoffman healch study. Participants receive $200 for Medical Terminology I 11/2 will completion of three or four laboratory sessions, Retirement Planning 12/7 scheduled 7 a.m. to noon, during which blood Princeton University. In 1970, Hoffman joined samples will be taken. If interested, call (301) the Biometry Branch of the Epidemiology and 295-3263 for more information. 0 Female Volunteers Needed Biometry Research Program, NICHD, as a NIA/D's Joyce Woodford Honored by AGA

Women, ages 18 through 39, who have regular menstrual cycles and are on no medica­ Joyce H. Woodford, deputy chief of the tions are needed to participate in a control Financial Management and Information group for an NICHD research protocol. This Systems Branch, NIAID, received che National will involve one clinic visit, phlebotomy and Chapter Service Award from the Association of pelvic ultrasound. Those interested should call Government Accountants (AGA), a national 496-4244.[)(gJ' 0 professional group for government financial Computer Training Classes managers. The AGA recognized Woodford for her Classes Dates influential work coward improving and Orientation to Running SAS on the Mainframe 9/16 developing the Montgomery-Prince George's SAS Fundamentals I for Programmers 9/17, 9/18 SAS Fundamentals I for Nonprogrammers 9/21, 9/22 chapter of the organization. The association's PC Viruses 9/23 90 chapters submit nominations for chis award, Macintosh Viruses 9/23 which they presented at their recent annual ENTER MAIL 9/23 training conference. BITNET 9/24 "It's a real honor to have been selected," said SAS Fundamentals II for Programmers 9/24, 9/25 Woodford. "When your chapter nominates SAS Fundamentals II for Nonprogrammers 9/29, 9/30 you, you do feel like you must have made a Joyce H. Woodford Managing Data Effectively 9/30 Intermediate PC-DOS 10/1-10/2 significant difference in expanding the Developing In-House Applications on the Mac 10/5 organization's scope." Beyond Basic WYLBUR 10/5-10/9 A member of AGA since 1979 and a former Minorities and Analysis of Ligand Binding Data chapter president, Woodford has a long record BiomedicalWoodfordResearch, has brought this concern for Using LIGAND Program 10/6 of contributions coward the association. Her education to NIH by organizing OS/2 2.0 Overview 10/7 ideas have helped promote education, as she an NIAID publication chat Topics in Flow Cyrometry 10/8-10/9 reconstructed and reactivated the AGA's identifies the inscicuce's programs helping scholarship program and initiated the Future minorities within the United Scates. Classes are offered by the DCRT Training Accountants Program. She also was the only She continues co serve as budget officer for Program without charge. Call 496-2339 for chapter president to offer her members three NIAID and as vice-chair of the emerging issues more information. 0 annual educational workshops. committee of AGA. 0 The Record page 16

Sept. 15, 1992

NIDDK Researcher Ad Bax Is World's Most Cited Chemist By Mark T. Sampson Dr. Ad Bax ofNIDDK's Laboratory of Chemical Physics has been declared the world's most cited chemist. The newsletter Science Watch analyzed publication and citation data for articles published in 339 chemistry journals between 1984 and 1990. Only articles that drew 15 or more citations on average were included in the survey. With an average of 47 citations per paper, Bax placed firstamong the 50 chemists listed. His total citations for the period surveyed exceeded 3,000, placing him above the citation ranks of four Nobel laureates, according to Science Watch, which analyzes trends and performance in science. But Bax smiles at the significance of his rank. "It's very nice to know chat people read our papers," he says. "But the citation record is just a matter of the practical usefulness to others of some of the methodology we have developed." The reason why his papers are so hot, he Dr. Ad Bax, chief ofNIDDK's section on biophysical nuclear magnetic resonance spectroscopy, works at his explains, is the growth in size and popularity of lab bench in the basement ofBldg. 2. At rear is one ofthe magnets he uses to study molecular structure. the field of nuclear magnetic resonance (NMR). Available since the l 940's, NMR is an analytical nucleic acids. Currently one of the most widely other scientists who produced many more tool of chemistry that uses magnetism to study used tools in chemistry, NMR has allowed papers during the same time. the structure and composition of molecules. chemises to study molecules with increasing Bax does not feel that the list indicates his NMR has grown tremendously within the accuracy. And for greater accuracy, chemists papers are more significant or superior to others past decade due to improvements in methodol­ turn to Bax. on the list. "I find it a great honor to be on the ogy and equipment, says Bax, chief of Bax also believes that his citation rank has to same list as four Nobel laureates," he says. "But NIDDK's section on biophysicalNMR do with the fact chat he usually describes in that does not mean that I would like to spectroscopy. Improving NMR methodology is detail how to conduct various experiments, compare our work, for example, to the original the focus of his research and the subject of his which allows other sci en tists to adapt these development of two-dimensionalNMR by papers. methods to their own needs. Richard Ernst," work for which the chemist, · NMR is used for a variety of purposes, from Still, the 64 papers produced by Bax's lab ranked tenth on the citation list, received the characterizing small organic molecules to during the 6-year period surveyed drew a much 1991 Nobel prize. 0 studying large molecules such as proteins and higher number of citations than the papers of Physician Volunteers Needed The Spanish Catholic Clinic is in urgent need of physicians who are willing to serve an immigrant Hispanic population in Montgom­ Don'teat your heart out. ery County. Knowledge of Spanish is preferred, but translators are available. Physicians may volunteer 2 hours weekly, biweekly, or monthly. The clinic is located in Langley Park and is beans, etc.) ¥ Eat more low-fat dairy foods open Monday through Friday from 8:30 a.m. to Eating right can reduce ¥ Eat moderate amounts of trimmed, lean red 5 p.m. If evening hours are preferred, they are your blood fewcholesterol level meat; skinless poultry; and fish ¥ Limit how negotiable. Contact Sister Martha, (301) 434- and your risk of heart disease. many egg yolks you eat ¥ Use unsaturated oils, 3999. D margarines and shortenings ¥ Choose breads Here are a pointers: ... and other baked goods made with unsaturated ¥ Eat "heart-healthy" foods containing ► vegetable 01ls, and little or no egg yolk CC Nursing Department Sponsors less fat, less saturated fat, less Seventh Annual Conference, Oct. 26 cholesterol ¥ Eat more J ¥ Choose "convemence" foods by how much SKI The Seventh Annual Oncology Nursing fruits, vegetables, saturated fat, total fat and cholesterol they contam-not Just cost ¥ Cut down how Conference, "Toward the Year 2000 ... Chal­ breads, cereals, and legumes much fat you cook with lenges in Oncology Nursing," sponsored by the (peas, Clinical Center Nursing Department, will be held Monday, Oct. 26, from 8 a.m. to 4 p.m., in Masur Auditorium, Bldg. 10. For registra­ IT'S YOUR HEART. tion information, contact the department's Marketing and Communications Division, 496- National Cholesterol Education Program National Heart, Lung, and Blood Institute; National Institutes of Health; Public Health Service;IT'S U.S. Department YOUR of Health and HumanLIFE. Services 5661. D

IT'S YOUR MOVE. U.S. GOVERNMENT PRINTING OFFICE 1992-281-825160026