GJA10 Antibody Cat. No.: 58-186

GJA10 Antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma; HC = hepatocarcinoma.

Specifications

HOST SPECIES: Rabbit

SPECIES REACTIVITY: Human, Mouse

This GJA10 antibody is generated from rabbits immunized with a KLH conjugated IMMUNOGEN: synthetic peptide between 484-515 amino acids from the C-terminal region of human GJA10.

TESTED APPLICATIONS: IHC-P, WB

For WB starting dilution is: 1:1000 APPLICATIONS: For IHC-P starting dilution is: 1:50~100

PREDICTED MOLECULAR 59 kDa WEIGHT:

September 26, 2021 1 https://www.prosci-inc.com/gja10-antibody-58-186.html Properties

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by PURIFICATION: dialysis

CLONALITY: Polyclonal

ISOTYPE: Rabbit Ig

CONJUGATE: Unconjugated

PHYSICAL STATE: Liquid

BUFFER: Supplied in PBS with 0.09% (W/V) sodium azide.

CONCENTRATION: batch dependent

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies STORAGE CONDITIONS: care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Additional Info

OFFICIAL SYMBOL: GJA9

Gap junction alpha-9 protein, Connexin-58, Cx58, Connexin-59, Cx59, Gap junction ALTERNATE NAMES: alpha-10 protein, GJA9, GJA10

ACCESSION NO.: P57773

PROTEIN GI NO.: 50403749

GENE ID: 81025

USER NOTE: Optimal dilutions for each application to be determined by the researcher.

Background and References

GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of BACKGROUND: transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins.

REFERENCES: 1) Hombach S, et al., EurNeurosci. 2004 May;19(10):2633-40.

2) Houghton FD, et al., Biol Reprod. 2002 May;66(5):1403-12.

3) Manthey D, et al.,Biol Chem. 1999 May 21;274(21):14716-23.

ANTIBODIES FOR RESEARCH USE ONLY.

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