Bioinformatics and Medical Informatics In the College of Sciences OFFICE: Geology/Mathematics/ 625 which is especially severe in the biotechnology and pharmaceutical TELEPHONE: 619-594-4573 industries, has been documented by various studies and discussed in E-MAIL: [email protected] the press. We can also observe a comparable demand in hospital and other clinical settings as the impact of new technologies spreads into clinical research and medical practice. Associated Faculty Research and development (R&D) in BIOMI can be categorized Faramarz Valafar, Ph.D., Associate Professor of Computer Science, into one of three branches. The first branch is the Director of and Medical Informatics development branch in which R&D specialists use mathematical and Andrew J. Bohonak, Ph.D., Professor of Biology engineering techniques to develop new, more efficient, and/or more Willa Fields, D.N.Sc., Professor of Nursing accurate methods to mine biological or clinical data. The second branch falls within the paradigm and primarily Roberta A. Gottlieb, M.D., Professor of Biology focuses on R&D in human-computer interface. The third branch seeks Richard A. Levine, Ph.D., Professor of Statistics to find answers to specific biological or medical questions including Kathleen L. McGuire, Ph.D., Professor of Biology drug development or working to uncover the underlying mechanisms Ralph-Axel Mueller, Ph.D., Professor of Psychology involved in specific biological systems or specific diseases. In the first Claire Murphy, Ph.D., Professor of Psychology year of the program, students in consultation with their graduate Usha Sinha, Ph.D., Professor of Physics adviser will take basic courses within two of the following four disci- William G. Tong, Ph.D., Distinguished Professor of Chemistry and plines: biology, chemistry, computer science, and mathematics/ Biochemistry statistics. B. Mikael Bergdahl, Ph.D., Associate Professor of Chemistry and For specialization in the algorithm development branch, students Biochemistry can choose courses and projects in areas such as statistics, data Robert A. Edwards, Ph.D., Associate Professor of Computer Science mining, , , search strategies, Scott Kelley, Ph.D., Associate Professor of Biology network architecture, digital image processing and advance imaging, Sunil Kumar, Ph.D., Associate Professor of Electrical and modeling, decisions systems design, and analytical studies in various Computer Engineering biological and clinical specializations. For specialization in the human-computer interface branch, students can choose courses and Chii-Dean Lin, Ph.D., Associate Professor of Statistics projects in areas such as principals of software design, human John J. Love, Ph.D., Associate Professor of Chemistry and interface design, network architecture, usability studies, Biochemistry design and management, and animation, CAD, Elizabeth R. Waters, Ph.D., Associate Professor of Biology and programming languages. For the third specialization students Robert W. Zeller, Ph.D., Associate Professor of Biology take a combination of courses in the areas listed above plus some Barbara Ann Bailey, Ph.D., Assistant Professor of Statistics specialized courses such as computer aided drug design. Elizabeth A. Dinsdale, Ph.D., Assistant Professor of Biology The change towards quantitative analysis in life and clinical sciences Kelly S. Doran, Ph.D., Assistant Professor of Biology has been so rapid that universities have been caught unprepared: few Kristin A. Duncan, Ph.D., Assistant Professor of Statistics offer suitable courses, and virtually none offer a well integrated Pamela Moses, Ph.D., Assistant Professor of Psychology curriculum that meets the needs that are sure to grow and evolve as life sciences become increasingly conceptual and quantitative. San Diego State University’s BIOMI graduate program offers two Adjunct Faculty related but distinct tracks. The first is a professional science master concentration preparing students for immediate productivity in University of California, San Diego: industrial or clinical settings. The second is a traditional master of Lucila Ohno-Machado, M.D., Ph.D., Professor of Medicine science preparing students for academic setting or continuation in a Gerard Hardiman, Ph.D., Associate Professsor of Medicine Ph.D. program. Hyeon-Eui Kim, Ph.D, M.P.H., R.N., Assistant Professor, Division of Biomedical Informatics Christopher H. Woelk, Ph.D., Assistant Professor, Admission to Graduate Study Division of Biomedical Informatics In addition to the general requirements for admission to the Genomics Institute of the Novartis Research Foundation: university with classified graduate standing, as described in Part Two Andrew I. Su, Ph.D., Computational Discovery of the Graduate Bulletin, a student must satisfy the following La Jolla Institute for Allergy and Immunology: requirements before being considered for recommendation to enter Bjoern Peters, Ph.D., Center for Infectious Disease the masters program. Anjano Rao, Ph.D., Signaling and Gene Expression Research (1) Meet the requirements deemed equivalent to a baccalaure- VA Hospital: ate degree in biology, chemistry, computer science, mathematics, Alan Calvitti, Ph.D., System Biology statistics, or a field in engineering. West Wireless Health Institute: (2) Meet BIOMI program’s expectations on the GRE General Test. Hassan Ghazemzadeh, Ph.D., Research Engineering Group (3) Be considered as capable of graduate work in bioinformatics or medical informatics by at least two references who have General submitted letters to the BIOMI program director. Bioinformatics and Medical Informatics (BIOMI) are multidisci- Students applying for admission should electronically submit the plinary fields at the intersection of and informatics, university application available at http://www.csumentor.edu along mathematics and statistics, biology, chemistry, and engineering. with the $55 application fee. The explosion in genomic information and in the elucidation of Students who do not meet all of the above requirements for pathways of various types has created an unprecedented, but largely admission with classified graduate standing may be admitted with unmet, need for professionals with a working knowledge of the conditionally classified graduate standing upon the recommendation biological sciences and computing/statistical methods. The shortage, of the research program. Students so admitted will be advised as to

SDSU GRADUATE BULLETIN 2012-2013 107 Bioinformatics and Medical Informatics the nature of their deficiency and the time to be allowed to achieve full 2. Complementary: Nine units in a field complementary to the stu- classified graduate standing. Conditions may include satisfactory dent’s background with approval of the graduate coordinator passing of certain undergraduate courses. These courses will be in selected from the following courses. addition to the minimum of 33-38 units required for the program. CHEM 567 Biochemistry Laboratory (3) Graduate Admissions CS 514 Database Theory and Implementation (3) CS 520 Advanced Programming Languages (3) All applicants must submit admissions materials separately to CS 535 Object-Oriented Programming and Design (3) SDSU Graduate Admissions and to the Bioinformatics and Medical CS 605 or Scientific Computing (3) Informatics program. COMP 605 The following materials should be submitted as a complete STAT 551A Probability and Mathematical Statistics (3) package directly to: STAT 551B Probability and Mathematical Statistics (3) Graduate Admissions Enrollment Services 3. Electives: Six units of approved 500-, 600-, or 700-level electives in San Diego State University disciplines related to the student’s specialization with approval of San Diego, CA 92182-7416 the graduate coordinator. (1) Official transcripts (in sealed envelopes) from all postsecondary 4. Six units of research including Thesis: institutions attended; BIOMI 797 Research (3) Cr/NC/RP Note: BIOMI 799A Thesis or Project (3) Cr/NC/RP • Students who attended SDSU need only submit tran- Professional Science Master Concentration scripts for work completed since last attendance. (Major Code: 07994) (SIMS Code: 771489) • Students with international coursework must submit both 1. Complete 12 units of required core courses. the official transcript and proof of degree. If documents BIOL 510 Molecular Evolution (3) are in a language other than English, they must be accompanied by a certified English translation. BIOMI 568 Bioinformatics (3) CHEM 560 General Biochemistry (3) (2) GRE scores (http://www.ets.org, SDSU institution code 4682); CS 600 Methods in Bioinformatics, Medical Informatics, (3) English language score, if medium of instruction was in a and Cheminformatics (3) language other than English (http://www.ets.org, SDSU institution code 4682). 2. Complementary: Twelve units in a field complementary to the stu- dent’s background with approval of the graduate coordinator Master of Science Degree in Bioinformatics selected from the following courses. and Medical Informatics CHEM 567 Biochemistry Laboratory (3) The following materials should be mailed or delivered to: CS 514 Database Theory and Implementation (3) Bioinformatics and Medical Informatics CS 520 Advanced Programming Languages (3) (BIOMI) Graduate Program CS 535 Object-Oriented Programming and Design (3) (Attention: Graduate Adviser) CS 605 or Scientific Computing (3) San Diego State University COMP 605 5500 Campanile Drive STAT 551A Probability and Mathematical Statistics (3) San Diego, CA 92182-7720 (1) Two letters of recommendation (in sealed and signed STAT 551B Probability and Mathematical Statistics (3) envelopes) from persons in a position to judge academic ability. 3. Electives: Nine units of approved 500-, 600-, or 700-level electives (2) Personal statement of motivating interest for the program; in disciplines related to the student’s specialization with approval also briefly describe research interests and educational and of the graduate coordinator. professional goals. 4. Five units of research including Thesis: Advancement to Candidacy BIOMI 797 Research (2) Cr/NC/RP or All students must satisfy the general requirements for BIOMI 798 Special Study (2) Cr/NC/RP advancement to candidacy, as described in Part Four of this bulletin. BIOMI 799A Thesis or Project 799 (3) Cr/NC/RP Specific Requirements for the Master of Science Degree Courses Acceptable on Master’s Degree (Major Code: 07994) (SIMS Code: 771490) Program in Bioinformatics and Medical In addition to meeting the requirements for classified graduate Informatics (BIOMI) standing and the basic requirements for the master's degree as Refer to Courses and Curricula and Regulations of the Division of Gradu- described in Part Four of this bulletin, the student must complete a ate Affairs sections of this bulletin for explanation of the course numbering program of study totaling 38 units for the concentration in professional system, unit or credit hour, prerequisites, and related information. science master and 33 units for the master of science as described UPPER DIVISION COURSES below: BIOMI 568. Bioinformatics (3) 1. Complete 12 units of required core courses. (Same course as Biology 568) BIOL 510 Molecular Evolution (3) Two lectures and three hours of laboratory. BIOMI 568 Bioinformatics (3) Prerequisite: Biology 366. CHEM 560 General Biochemistry (3) Bioinformatics analysis methods and programming skills. Practical CS 600 Methods in Bioinformatics, Medical Informatics, bioinformatic software for sequence analysis, bioinformatic and Cheminformatics (3) and programming fundamentals.

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BIOMI 596. Special Topics in Bioinformatics and Medical BIOMI 798. Special Study (1-3) Cr/NC/RP Informatics (1-4) Prerequisite: Consent of staff; to be arranged with graduate Prerequisite: Consent of instructor. coordinator. Advanced selected topics in bioinformatics and medical informat- Individual study. Maximum credit six units applicable to a master's ics. May be repeated with new content. See Class Schedule for spe- degree. cific content. Limit of nine units of any combination of 296, 496, 596 BIOMI 799A. Thesis or Project (3) Cr/NC/RP courses applicable to a bachelor's degree. Credit for 596 applicable Prerequisites: An officially appointed thesis committee and to a master's degree with approval of the graduate adviser. advancement to candidacy. Preparation of a project or thesis for the master's degree. GRADUATE COURSES BIOMI 799B. Thesis Extension (0) Cr/NC BIOMI 600. Methods in Bioinformatics, Medical Informatics, and Prerequisite: Prior registration in Thesis 799A with an assigned Cheminformatics (3) grade symbol of RP. (Same course as Computer Science 600) Registration required in any semester or term following assignment Prerequisites: Three units of calculus and graduate standing. of RP in Course 799A in which the student expects to use the facilities Computer, mathematical, and engineering techniques for bioinfor- and resources of the university; also student must be registered in the matics, cheminformatics, and medical informatics. Techniques used course when the completed thesis is granted final approval. in microarray data analysis, gene and protein sequence alignment, and classification techniques in medical decision making. BIOMI 797. Research (1-3) Cr/NC/RP Prerequisite: Consent of instructor. Research in one of the fields of bioinformatics and medical infor- matics. Maximum credit six units applicable to a master's degree.

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