Record #1 of 15
ID: CN-00801300
AU: Wu W
AU: Cannon PS
AU: Yan W
AU: Tu Y
AU: Selva D
AU: Qu J
TI: Effects of Merogel coverage on wound healing and ostial patency in endonasal endoscopic dacryocystorhinostomy for primary chronic dacryocystitis.
SO: Eye (London, England)
YR: 2011
VL: 25
NO: 6
PG: 746-53
PM: PUBMED 21394118
PT: Journal Article; Randomized Controlled Trial
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/300/CN-00801300/frame.html
KY: Chronic Disease; Dacryocystitis [drug therapy] [surgery]; Dacryocystorhinostomy [methods]; Endoscopy; Epithelium [pathology]; Follow-Up Studies; Hyaluronic Acid [therapeutic use]; Metronidazole [pharmacokinetics] [pharmacology]; Nasal Mucosa [pathology]; Wound Healing [drug effects]; Adult; Female; Humans; Male; Middle Aged
AB: PURPOSE: To investigate the effects of Merogel coverage on ostial patency in endonasal endoscopic dacryocystorhinostomy (EES-DCR) for primary chronic dacryocystitis (PCD).METHODS: In all, 260 patients with unilateral PCD were randomized into two groups: the Merogel group and the control group. All patients underwent EES-DCR. The Merogel group received Merogel covering the wound 1-2 mm around the ostium and the control group received no treatment. Patients were followed up for 9 months. The mucosal epithelialization of the wound, the proliferation of fibrosis tissue, and the success rate of ostial patency were compared.RESULTS: Our study included 112 patients in the Merogel group and 115 patients in the control group. At the 2-week review, intact mucosal epithelium lined the ostia in 96 Merogel patients compared with 80 control patients (ITT analysis: χ(2)=4.502, P=0.034). At the 9- month review, scars were present in 18 patients in the Merogel group compared with 39 patients in the control group (ITT analysis: χ(2)=9.909, P=0.002, ITT analysis). No differences were observed in the granulation formation between the two groups. The success rate of ostial patency reached 94.6% (106/112) in the Merogel group compared with 80% (92/115) in the control group (ITT analysis: χ(2)=4.151, P=0.042).CONCLUSION: Merogel coverage may enhance the success rate of EES-DCR for PCD by promoting mucosal epithelial healing and preventing excessive scarring.
Record #2 of 15
ID: CN-00778619
AU: Tirakunwichcha S
AU: Aeumjaturapat S
AU: Sinprajakphon S
TI: Efficacy of mitomycin C in endonasal endoscopic dacryocystorhinostomy.
SO: The Laryngoscope
YR: 2011
VL: 121
NO: 2
PG: 433-6
PM: PUBMED 21271601
PT: Journal Article; Randomized Controlled Trial
AD: Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand. [email protected]
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/619/CN-00778619/frame.html
KY: Dacryocystorhinostomy [methods]; Endoscopy; Follow-Up Studies; Intraoperative Period; Lacrimal Duct Obstruction [surgery]; Mitomycin [therapeutic use]; Nasolacrimal Duct [surgery]; Adult; Female; Humans; Male
AB: OBJECTIVES/HYPOTHESIS: To evaluate the efficacy of intraoperative mitomycin C (MMC) in endonasal endoscopic dacryocystorhinostomy.STUDY DESIGN: Randomized controlled trial.METHODS: Fifty patients with primary acquired nasolacrimal duct obstruction were enrolled and randomly allocated into the treatment and control group. The patients underwent standard endonasal endoscopic dacryocystorhinostomy with mucosal flaps and mitomycin C or placebo on each group. The ostium size was measured at 3 months, 6 months, and 12 months to evaluate the effect of mitomycin C and placebo, and the patency of the lacrimal drainage system was assessed.RESULTS: There was no statistical significance in the success rate between the MMC group and the control group at 1-year follow-up (84.6% vs.79.2%, respectively, P = .59). At the 6-month and 12-month visits, the mean ostium size in the MMC group was 10.8 mm(2) (SD = 3.17) and 3.0 mm(2) (SD = 1.78), respectively, which were prominently larger than the control group at 7.1 mm(2) (SD = 2.62; P < .001, 95% CI, 0.84-5.45) and 1.6 mm(2) (SD = 1.18; P = .004, 95% CI, 0.49-2.38).CONCLUSIONS: There was no statistically significant difference in the success rates of both groups, but MMC seems to have a conspicuous effect on the healing process at the ostium.
Record #3 of 15
ID: CN-00811598
AU: Ragab SM
AU: el-Koddousy MS
AU: Badr M
TI: Endocanalicular, high-pressure balloon catheter, endoscopic dacryocystorhinostomy: a randomized controlled trial.
SO: Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology- Head and Neck Surgery
YR: 2011
VL: 145
NO: 4
PG: 683-8
PM: PUBMED 21613626
PT: Journal Article; Randomized Controlled Trial
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/598/CN-00811598/frame.html
KY: Balloon Dilation [methods]; Dacryocystorhinostomy [methods]; Endoscopes; Endoscopy [instrumentation] [methods]; Equipment Design; Lacrimal Duct Obstruction [therapy]; Nasolacrimal Duct; Prospective Studies; Adult; Female; Humans; Male; Middle Aged; Young Adult AB: OBJECTIVES: To conduct a prospective randomized controlled study to investigate the safety and efficacy of endocanalicular, high-pressure, 5-mm balloon catheter, endoscopic dacryocystorhinostomy (DCR) in adult patients with acquired complete nasolacrimal obstruction.STUDY DESIGN: Prospective randomized controlled study.SETTING: General hospital.SUBJECTS AND METHODS: Sixty-six adult patients with a total of 70 procedures were recruited to undergo endoscopic DCR. They were prospectively, equally randomized into 2 groups: endocanalicular, high-pressure, 5-mm balloon catheter, endoscopic DCR (group I) and conventional endoscopic DCR (group II). Regular follow-up sessions were conducted to document the patient's subjective improvement, judge ostium patency on irrigation, and record any complications.RESULTS: Both groups demonstrated a success rate of 91.4%. There was a shorter mean operative time (25.7 minutes) in group I (P < .001). The number of adverse events was significantly higher in group II (P < .05). Group I showed statistically significantly more comfort during surgery under local anesthesia with minimal sedation (P < .05).CONCLUSION: Endocanalicular balloon catheter endoscopic DCR shares the advantages and success rate of conventional endoscopic DCR. In addition, the former is simpler, requires less manipulation, consumes a shorter operative time, has a better safety profile, and can be conducted under local anesthesia with minimal sedation.
Record #4 of 15
ID: CN-00812568
AU: Basmak H
AU: Cakli H
AU: Sahin A
AU: Gursoy H
AU: Ozer A
AU: Colak E
TI: What is the role of partial middle turbinectomy in endocanalicular laser-assisted endonasal dacryocystorhinostomy?
SO: American journal of rhinology & allergy
YR: 2011
VL: 25
NO: 4
PG: e160-5 PM: PUBMED 21333092
PT: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/568/CN-00812568/frame.html
KY: Dacryocystorhinostomy; Follow-Up Studies; Lacrimal Apparatus [metabolism] [pathology] [surgery]; Lacrimal Apparatus Diseases [diagnosis] [pathology] [physiopathology] [surgery]; Lasers [utilization]; Nasolacrimal Duct [pathology] [surgery]; Prospective Studies; Recovery of Function; Turbinates [pathology] [surgery]; Adult; Aged; Female; Humans; Male; Middle Aged
AB: BACKGROUND: This study was designed to compare outcomes of endocanalicular laser-assisted endonasal dacryocystorhinostomy (DCR) with and without partial anterior middle turbinectomy.METHODS: A prospective randomized comparative study was conducted on 91 subjects with primary acquired nasolacrimal duct obstruction, undergoing endocanalicular (ECL) procedures. Group 1 was composed of 44 (7 bilateral) patients undergoing ECL diode laser-assisted endonasal DCR without partial anterior middle turbinectomy and group 2 was composed of 47 (7 bilateral) patients undergoing partial anterior middle turbinectomy and ECL diode laser-assisted endonasal DCR. Follow-up period was 11.0 (6.0-14.5 months) months for group 1 and 9.2 (5.0-14.2 months) months for group 2. Functional success was defined as absence of epiphora and anatomic success was defined as ability to irrigate the lacrimal system. Anatomic and functional success at the 1st week, 3rd month, and final postoperative examinations of two groups were compared using chi-square tests.RESULTS: Final anatomic successes were 39/51 (76%) cases for group 1 and 51/54 (94%) cases for group 2. Final functional successes were 36/51 (%71) patients in group 1 and 48/54 (88%) patients in group 2. Group 2 had higher success at the final examination and the difference was statistically significant.CONCLUSION: We recommend partial anterior middle turbinectomy in all laser ECL laser-assisted endonasal DCR, but further studies with larger sample sizes are needed to strengthen our hypothesis.
Record #5 of 15
ID: CN-00751534
AU: Kashkouli MB
AU: Pakdel F
AU: Hashemi M
AU: Ghaempanah MJ
AU: Rezaee R
AU: Kaghaz-Kanani R
AU: Ahadian A TI: Comparing anatomical pattern of topical anti-glaucoma medications associated lacrimal obstruction with a control group.
SO: Orbit (Amsterdam, Netherlands)
YR: 2010
VL: 29
NO: 2
PG: 65-9
PM: PUBMED 20394542
PT: Comparative Study; Controlled Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
AD: Iran University Eye Research Center, Rassoul Akram Hospital, Tehran, Iran. [email protected]
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/534/CN-00751534/frame.html
KY: Administration, Topical; Adolescent; Antihypertensive Agents [adverse effects]; Cross-Sectional Studies; Glaucoma [drug therapy]; Lacrimal Duct Obstruction [chemically induced] [diagnosis]; Nasolacrimal Duct [drug effects] [pathology]; Ophthalmic Solutions [adverse effects]; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Young Adult
CC: SR-EYES
AB: PURPOSE: To compare the anatomical pattern of lacrimal drainage system obstruction (LDSO) associated with topical anti-glaucoma medications (AGM) with a control group.METHODS: In a cross- sectional controlled study, case group included patients on topical anti-glaucoma medications and control group included patients with no history of glaucoma, free of ocular disease, and not using topical medications. Data recording, eye examination, and categorization of patients into case and control groups were performed by a senior ophthalmology resident. Diagnostic probing and irrigation test was performed by an oculoplastic surgeon who was masked to the patients' data. Chi-square (X(2)) and tests were used to assess the effect of sex and systemic diseases, as well as logistic regression analysis with intra-cluster correlation for the effect of topical anti-glaucoma medications on lacrimal drainage system, and then independent sample t-tests to compare the mean ages, plus the binary logistic regression test for the effect of increasing age on LDSO.RESULTS: There were 128 eyes of 96 patients in the case and 277 eyes of 172 patients in the control group. Two groups were similar regarding to the age, sex, and associated systemic disorders (0.3
Record #6 of 15
ID: CN-00750498
AU: Komínek P
AU: Cervenka S
AU: Matousek P
TI: Does the length of intubation affect the success of treatment for congenital nasolacrimal duct obstruction?
SO: Ophthalmic plastic and reconstructive surgery
YR: 2010
VL: 26
NO: 2
PG: 103-5
PM: PUBMED 20305509
PT: Comparative Study; Journal Article; Randomized Controlled Trial
AD: Department of Otolaryngology, University Hospital Ostrava, Czech Republic. [email protected]
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/498/CN-00750498/frame.html
KY: Fluorescein [metabolism]; Fluorescent Dyes [metabolism]; Intubation [instrumentation] [methods]; Lacrimal Duct Obstruction [congenital] [metabolism] [therapy]; Nasolacrimal Duct; Prospective Studies; Silicones; Stents; Time Factors; Treatment Outcome; Child, Preschool; Humans; Infant
CC: SR-EYES
AB: PURPOSE: To compare success rates of intubation for 2 versus 5 months in congenital nasolacrimal duct obstruction in children between 15 and 30 months of age.METHODS: This prospective, randomized study evaluated drainage function in 145 eyes of children aged between 15 and 30 months and treated for congenital nasolacrimal duct obstruction using silicone stents with the fluorescein dye disappearance test. The tubes were removed 2 months (group I, 48 eyes) and 5 months (group II, 47 eyes) after stent placement. Thereafter, the children were followed for 6 months after tube removal. Fifty eyes were excluded from the study because of incomplete follow-up.RESULTS: The full resolution of symptoms (fluorescein test 0-1) was 33 of 48 in group I and 33 of 47 in group II at the time of tube removal (2 vs. 5 months). Six months after tube removal, the success rate was 43 of 48 (89.6%) in group I and 43 of 47 (91.5%) in group II. After the stents were removed, no relapses were observed in children having a fluorescein test 0-1 with the tubes remaining in the lacrimal system.CONCLUSIONS: The effects of intubation for 2 versus 5 months on the function of the nasolacrimal duct during and after intubation in children between 15 and 30 months of age are comparable. The fluorescein dye disappearance test is the test of choice for monitoring lacrimal drainage function.
Record #7 of 15
ID: CN-00749084
AU: Naiboglu B
AU: Deveci I
AU: Kalaycik C
AU: Daylan A
AU: Habesoglu TE
AU: Toros SZ
AU: Deveci SE
AU: Egeli E
TI: Effect of nasolacrimal duct obstruction on nasal mucociliary transport.
SO: The Journal of laryngology and otology
YR: 2010
VL: 124
NO: 2
PG: 166-70
PM: PUBMED 19874638
PT: Journal Article; Randomized Controlled Trial
AD: Otorhinolaryngology Clinic, Haydarpasa Numune Education and Research Hospital, Istanbul, Turkey. [email protected]
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/084/CN-00749084/frame.html KY: Fluorescein [diagnostic use]; Lacrimal Duct Obstruction [diagnosis] [etiology] [physiopathology]; Mucociliary Clearance [physiology]; Prospective Studies; Saccharin [diagnostic use]; Time Factors; Adult; Female; Humans; Male; Middle Aged
AB: BACKGROUND: Most patients with nasolacrimal duct obstruction have dry, crusty nasal mucosa. Mucociliary clearance is modulated by the amount and biochemical composition of nasal mucus. Nasolacrimal duct obstruction disturbs the drainage of tears into the nasal cavity.OBJECTIVE: We examined the effect of nasolacrimal duct obstruction on the mucociliary transport of nasal mucosa, by comparing saccharine test results for epiphora patients versus healthy volunteers.STUDY DESIGN: Prospective, randomised, clinical trial.METHODS: Eight patients with bilateral epiphora and 10 patients with unilateral epiphora were included in the study group. Complete nasolacrimal duct obstruction was demonstrated by studying irrigation of the nasolacrimal system, and by fluorescein dye study. The control group comprised 20 healthy volunteers. Mucociliary transport was assessed by the saccharine test in both the study and control groups. The saccharine transit times of 26 impaired nasal cavities were compared with those of 20 healthy nasal cavities of controls. Also, the saccharine transit times of the healthy nasal cavities of the 10 patients with unilateral epiphora were compared with those of their diseased sides, and also with those of healthy volunteers.RESULTS: The saccharine transit times of the epiphora patients were statistically significantly greater than those of the control group. Also, there was a statistically significant difference in saccharine transit times, comparing the healthy and impaired nasal cavities of patients with unilateral epiphora.CONCLUSION: Nasolacrimal duct obstruction has a negative effect on nasal mucociliary clearance. This may be related to changes in the amount and biochemical composition of nasal mucus.
Record #8 of 15
ID: CN-00768035
AU: Javate RM
AU: Pamintuan FG
AU: Cruz RT
TI: Efficacy of endoscopic lacrimal duct recanalization using microendoscope.
SO: Ophthalmic plastic and reconstructive surgery
YR: 2010
VL: 26
NO: 5
PG: 330-3 PM: PUBMED 20592632
PT: Comparative Study; Journal Article; Randomized Controlled Trial
AD: Department of Ophthalmology, University of Santo Tomas Hospital, University of Santo Tomas, Sampaloc, Manila, Philippines. [email protected]
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/035/CN-00768035/frame.html
KY: Dacryocystorhinostomy [methods]; Endoscopes; Endoscopy [instrumentation] [methods]; Follow-Up Studies; Lacrimal Duct Obstruction [metabolism] [physiopathology] [surgery]; Nasolacrimal Duct [physiopathology] [surgery]; Prospective Studies; Tears [secretion]; Treatment Outcome; Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged
AB: PURPOSE: To describe a new endoscopic procedure to restore the passage of tears in an obstructed lacrimal drainage system and to compare its efficacy with the standard external dacryocystorhinostomy (SE-DCR).METHODS: Patients with complete and partial primary acquired nasolacrimal duct obstruction (PANDO) were randomly allocated to 2 treatment groups using completely randomized design. The first group was treated using endoscopic lacrimal duct recanalization (ELDR), while the second group was treated using SE-DCR. Follow-up was conducted for at least 6 months and evaluated for anatomical and functional patency. Complications were also noted for both groups.RESULTS: A total of 86 patients underwent ELDR, 60 of whom had complete PANDO, while 26 patients had partial PANDO. Eighty patients underwent SE-DCR; 58 had complete PANDO, and 22 had partial PANDO. The combined success rate in terms of anatomical patency for ELDR was 93.02% (95% confidence interval [CI], 0.88-98) compared with 93.75% (95% CI, 0.87-90) for SE-DCR (p = 0.85). Meanwhile, the combined success rate (functional patency) for ELDR is 84.88% (95% CI, 0.77-93) versus 90.00% (95% CI, 0.83-97) for SE-DCR (p = 0.32).CONCLUSIONS: ELDR using microendoscope is as efficacious as SE-DCR, without its associated major complications.
Record #9 of 15
ID: CN-00772297
AU: Andalib D
AU: Gharabaghi D
AU: Nabai R
AU: Abbaszadeh M
TI: Monocanalicular versus bicanalicular silicone intubation for congenital nasolacrimal duct obstruction.
SO: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus / American Association for Pediatric Ophthalmology and Strabismus YR: 2010
VL: 14
NO: 5
PG: 421-4
PM: PUBMED 21035069
PT: Comparative Study; Journal Article; Randomized Controlled Trial
AD: Strabismus and Oculoplastic Unit, Nikookary Eye Hospital, Tabriz University of Medical Sciences, Tabriz, Iran. [email protected]
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/297/CN-00772297/frame.html
KY: Anesthesia; Device Removal; Intubation [instrumentation] [methods]; Lacrimal Duct Obstruction [congenital] [therapy]; Nasolacrimal Duct; Outpatients; Silicones; Stents; Treatment Outcome; Child; Child, Preschool; Humans; Infant
CC: SR-EYES
AB: PURPOSE: To compare the success rate of monocanalicular versus bicanalicular silicone intubation of the nasolacrimal duct for congenital nasolacrimal duct obstruction (CNLDO).METHODS: In a prospective randomized clinical trial, 70 eyes of 57 children with CNLDO underwent either monocanalicular silicone intubation (MCI) (n = 35 eyes) or bicanalicular silicone intubation (BCI) (n = 35 eyes). All procedures were performed by 1 oculoplastic surgeon. Tube removal was planned for 3 months postoperatively. The results were assessed using a Munk score. Treatment success was defined as Munk score 0-1 at 3 months after tube removal.RESULTS: The surgical outcome was assessed in 29 eyes with MCI and 27 eyes with BCI. The mean age of treatment was 34.9 ± 12.7 months for MCI and 38.7 ± 18.6 months for BCI. Treatment success was achieved in 25 of 29 eyes (86.2%; 95% CI, 79%-96%) in the MCI group compared with 24 of 27 eyes (89%; 95% CI, 84%-94%) in the BCI group (RR = 0.96; 95% CI, 0.79-1.18). There were no corneal or canalicular complications in either group.CONCLUSIONS: MCI and BCI were successful in a similar percentage of children with CNLDO. The mainadvantage of the former technique was easy tube removal without sedation in the office.
Record #10 of 15
ID: CN-00803597
AU: Liu H-F
AU: Zheng A-Z AU: Chen Z-L
TI: [Observation on curative effect of double-flap or single-flap anastomosis in two different external dacryocystorhinostomy methods] LA: Chi
SO: International Journal of Ophthalmology
YR: 2010
VL: 10
NO: 5
PG: 1007-8
XR: EMBASE 2010309422
DE: RCT PT: Journal: Article
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/597/CN-00803597/frame.html
KY: *Anastomosis; Article; Comparative Study; *Dacryocystorhinostomy; *Double Flap Anastomosis; Eye; Follow up; Human; Major Clinical Study; Observational Study; *Single Flap Anastomosis; Suturing Method; Therapy Effect; Treatment Outcome
AB: AIM: To compare the curative effect of the external dacryocystorhinostomy (DCR), using two different patterns of flap anastomosis with suturing of two flaps or anterior flap. METHODS: Fifty-six eyes 48 patients were randomized and assigned to two groups on the basis of the pattern of flap anastomosis. In double-flap group with 25 eyes 20 patients, posterior and anterior flaps were separately sutured. In single-flap group with 31 eyes 28 patients, only the anterior flaps were sutured after resecting of both posterior flaps. RESULTS: The time of follow-up was 6-10 months for all patients. The final success rates in double-flap groups were 92% and in single-flap group were 90% respectively. There was no significant statistical difference in success rate between the groups. CONCLUSION: DCR with double-flap anastomosis has no advantage over only anterior flap. Anastomosis by only anterior flap and resected posterior flap is easier to perform and does not appear adversely to affect the outcome of DCR surgery.
Record #11 of 15
ID: CN-00778494
AU: Choontanom R
TI: Probing and syringing with 3% solution of NaCl and/or 0.2 mg/ml mitomycin-C in nasolacrimal duct obstruction patients. SO: Journal of the Medical Association of Thailand = Chotmaihet thangphaet
YR: 2010
VL: 93 Suppl 6
PG: S197-202
PM: PUBMED 21280534
PT: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
AD: Department of Ophthalmology, Phramongkutklao College of Medicine, Bangkok, Thailand. [email protected]
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/494/CN-00778494/frame.html
KY: Antibiotics, Antineoplastic [administration & dosage]; Lacrimal Duct Obstruction [therapy]; Mitomycin [administration & dosage]; Nasolacrimal Duct [surgery]; Pain Measurement; Prospective Studies; Sodium Chloride [therapeutic use]; Syringes; Therapeutic Irrigation [methods]; Treatment Outcome; Adult; Aged; Female; Humans; Male; Middle Aged
CC: SR-EYES
AB: OBJECTIVE: To compare the efficacy of lacrimal probing and syringing among 3% solution of Sodium Chloride and/or 0.2 mg/ ml Mitomycin-C as an adjunctive medication.DESIGN: A prospective, randomized, 2 by 2 factorial design study.MATERIAL AND METHOD: Forty-eight of nasolacrimal duct obstruction patients with epiphora symptom were randomly assigned to receive either Normal Saline Solution or 3% solution of Sodium Chloride or 0.2 mg/ml Mitomycin-C solution or combined 3% solution of Sodium Chloride with 0.2 mg/ml Mitomycin-C solution, during office probing and syringing. The intervention was performed repeatedly at week 0, weeks 2 and 4. An assessment of epiphora with Visual Analogue Scale were evaluated at week 0, weeks 2, 4, 8 and 12.RESULTS: Probing and syringing was successfully reducing epiphora symptom. Mitomycin-C group showed a significant reduction in mean difference of Visual Analogue Scale score compared with Normal Saline Solution group (2.85, 95% CI: 1.164-4.536, p < 0.001) and 3% Sodium Chloride group (2.175, 95% CI: 0.489-3.861, p < 0.01). No complication or adverse event was found.CONCLUSION: 0.2 mg/ml Mitomycin-C solution of was the most effective medication for office probing and syringing in reducing epiphora symptom in nasolacrimal duct obstruction patients.
Record #12 of 15
ID: CN-00803573
AU: Li L-C AU: Ouyang L
AU: Li D-J
AU: Huang Q
TI: [Ring silicone tube implantation combined with mitomycin C for the treatment of upper lacrimal duct obstruction] LA: Chi
SO: International Journal of Ophthalmology
YR: 2010
VL: 10
NO: 1
PG: 187-8
XR: EMBASE 2010094435
DE: RCT PT: Journal: Article
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/573/CN-00803573/frame.html
KY: Article; Controlled Study; Drug Effect; Extubation; Eye Surgery; Human; *Lacrimal Duct Occlusion; Dt [Drug Therapy]; *Lacrimal Duct Occlusion; Su [Surgery]; Major Clinical Study; Silastic Tube; *Mitomycin C; Dt [Drug Therapy]
AB: AIM: To study the effect of ring silicone tube implantation combined with mitomycin C for the treatment of upper lacrimal duct obstruction. METHODS: Eighty-nine cases (116 eyes) with upper lacrimal duct obstruction underwent the procedure of intubation in outpatient clinic: tears points obstruction(14 eyes), lacrimal duct obstruction (38 eyes), tears explorer obstruction (64 eyes). The patients were randomly divided into 2 groups. Group A consisted of 44 cases (58 eyes): tears points obstruction (6 eyes), lacrimal duct obstruction (20 eyes), nasolacrimal duct obstruction (32 eyes). Group B consisted of 45 cases (58 eyes): tears points obstruction(8 eyes), lacrimal duct obstruction(18 eyes), nasolacrimal duct obstruction (32 eyes). The materials were silicone tube, duct expansion wire which was made by myself. Two-canalicular-nasolacri-mal duct were installed ring silicone tube. The time of extubation was after 3-6 months. If the patients were also with nasolacrimal duct obstruction, inverse ball silicone tube implantation in nasolacrimal canal should be performed immediately after the extubation of the ring silicone tube. What group B distinguished from group A was indwelling duct expansion wire which is immersed in 0. 25mg/mL mitomycin C for 3-5 minutes, lacrimal duct was washed regularly after extubation of ring silicone tube, and the patients were followed up for 2 years. RESULTS: The cure rate of group A was 72. 4%, the cure rate of group B was 93. 1%. There were significant differences in recovery rate between the two groups(P < 0. 01). CONCLUSION: The method of installing ring silicone tube under mitomycin C can improve the success rate of surgery and can be a better way to cure upper lacrimal duct obstruction.
Record #13 of 15
ID: CN-00748445
AU: Elmorsy S
AU: Fayek HM
TI: Rubber tube versus silicone tube at the osteotomy site in external dacryocystorhinostomy.
SO: Orbit (Amsterdam, Netherlands)
YR: 2010
VL: 29
NO: 2
PG: 76-82
PM: PUBMED 20394544
PT: Comparative Study; Journal Article; Randomized Controlled Trial
AD: ENT Department, Mansoura University, Egypt. [email protected]
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/445/CN-00748445/frame.html
KY: Dacryocystorhinostomy [instrumentation] [methods]; Intubation; Lacrimal Duct Obstruction [surgery]; Nasolacrimal Duct [surgery]; Osteotomy; Prospective Studies; Rubber; Silicone Elastomers; Stents; Treatment Outcome; Adult; Female; Humans; Male; Middle Aged
CC: SR-EYES
AB: BACKGROUND: In external dacryocystorhinostomy a large bony window is created in the lateral nasal wall and a mucosal anastomosis is created between the lacrimal sac and the nasal cavity. The success of the operation depends on the surgical anastomosis remains patent and converting to a wide enough epithelial-lined passage.OBJECTIVE: To compare the efficacy of using rubber versus silicone tubes at the osteotomy of Dacryocystorhinostomy.DESIGN: Prospective, randomized, hospital-based study.SUBJECTS AND METHODS: 46 patients diagnosed with primary acquired nasolacrimal duct obstruction were assigned randomly to rubber, silicone or control group. The surgical procedures in the three groups were the same except that in patients of rubber and silicone groups, rubber or silicone tubes were placed at osteotomy opening and removed after 3 months. Transnasal endoscopic findings were recorded at the completion of surgery and at 3 months, 6 months and 9 monthes after surgery for the 3 groups. A computer aided digitizer was used to calculate the surface area of the osteotomy site. Results: After removal of their tubes, 3 patients in the rubber group had recurrent epiphora (78.0% success), one patient in silicone group (92.86% success) and 4 patients in control group (77.8% success). The average final surface area of the osteotomy opening of patients with rubber group at the end of follow-up was (9.85 mm(2)) in the silicone group was (17.47 mm(2)), whereas in the control group was (8.56 mm(2)).CONCLUSION: Silicone tube is better than rubber one in maintaining effective larger osteotomy after Dacryocystorhinostomy. This can improve the long-term success of the operation.
Record #14 of 15
ID: CN-00772991
AU: Chen F
AU: Wang J
AU: Chen W
AU: Shen M
AU: Xu S
AU: Lu F
TI: Upper punctal occlusion versus lower punctal occlusion in dry eye.
SO: Investigative ophthalmology & visual science
YR: 2010
VL: 51
NO: 11
PG: 5571-7
PM: PUBMED 20463310
PT: Comparative Study; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
AD: School of Ophthalmology and Optometry, Wenzhou Medical College, Wenzhou, Zhejiang, China.
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/991/CN-00772991/frame.html
KY: Collagen; Cornea [physiology]; Dry Eye Syndromes [physiopathology]; Eyelids [physiopathology]; Fluorophotometry; Lacrimal Duct Obstruction [physiopathology]; Prospective Studies; Prostheses and Implants; Questionnaires; Tears [chemistry]; Tomography, Optical Coherence; Female; Humans; Male; Young Adult
CC: SR-EYES
AB: PURPOSE: To compare the effectiveness of upper punctal occlusion versus that of lower punctal occlusion in dry eye patients.METHODS: One eye's upper punctum and the contralateral eye's lower punctum were occluded with collagen plugs in 20 dry eye patients. The same procedure was performed in 20 normal subjects. The upper and lower tear menisci were imaged simultaneously by real-time OCT before punctal occlusion and repeated on days 1, 4, 7, and 10 afterward. The subjective symptom score, corneal fluorescein staining intensity, Schirmer I test result, and tear breakup time (TBUT) were also determined.RESULTS: In dry eye patients, occlusion of either punctum improved symptom scores, fluorescein staining scores, TBUT, and lower tear meniscus height (LTMH, P < 0.05); however, Schirmer test scores and upper tear meniscus height (UTMH) did not change after occlusion (P > 0.05). There was no significant difference for any of these variables between upper punctum- and lower punctum- occluded eyes, before or after occlusion (P > 0.05). In normal subjects, Schirmer test scores, TBUT, UTMH, and LTMH did not change over time (P > 0.05).CONCLUSIONS: Punctal occlusion with collagen plugs in dry eye patients leads to the relief of subjective symptoms and the improvement of objective signs. The effectiveness of occluding the upper or lower punctum is similar. The LTMH is a valid indicator of the success of punctal occlusion.
Record #15 of 15
ID: CN-00766972
AU: Gock G
TI: Use of mitomycin C to improve endonasal dacryocystorhinostomy (DCR) success rates
SO: ICTRP [accessed 14 Oct 2010]
YR: 2010
PG: ID: ISRCTN15566163
DE: RCT
UF: http://www.controlled-trials.com/ISRCTN15566163
US: http://www.mrw.interscience.wiley.com/cochrane/clcentral/articles/972/CN-00766972/frame.html
CC: SR-ENT; SR-EYES
PMID- 22732136 OWN - NLM
STAT- Publisher
DA - 20120626
IS - 1945-8932 (Electronic)
IS - 1945-8932 (Linking)
DP - 2012 Jun 21
TI - Primary endoscopic dacryocystorhinostomy with or without silicone tubing: A
prospective randomized study.
AB - BACKGROUND: Endoscopic dacryocystorhinostomy (DCR) is an effective surgical
procedure to treat saccal and postsaccal stenosis or nasolacrimal duct
obstruction. The use of silicone tube after endoscopic DCR is still
controversial. A prospective randomized study was conducted to compare the
success rate between the use of silicone stent and no use of silicone stent in
endoscopic DCR.METHODS: A prospective randomized study was conducted at Aseer
Central Hospital and Abha Private Hospital, Abha, Kingdom of Saudi Arabia, on
allpatients undergoing endoscopic DCR between July 1, 2006 and 30 June 30, 2010.
Patients were allocated randomly for endoscopic DCR with or without stent. The
data collection included age, sex, diagnosis, method, and duration of surgery.
Patients were followed up postoperatively at 1 week, 1 month, and then every 3
months for 1 year.RESULTS: During the period of the study a total of 173 cases of
postsaccal stenosis underwent endoscopic DCR (67 male and 106 female subjects).
The meanage was 51.8 years (range, 18-72 years). A stent was used in 92 patients
(53.2%) and not used in 81 patients (46.8%). With silicone tubing the success
rate was 96%, and without silicone tubing it was 91%, an overall success rate of
94%. The odds ratio of failure without a silicone tube was 3.25 but confidence interval was from 0.84 to 12.60 and the difference between these two groups was
statistically not significant (p = 0.117).CONCLUSION: In this study, there was no
statistically significant advantage of using endoscopic DCR with stent over the
endoscopic DCR without stent.
AU - Qahtani AS
LA - ENG
PT - JOURNAL ARTICLE
DEP - 20120621
TA - Am J Rhinol Allergy
JT - American journal of rhinology & allergy
JID - 101490775
EDAT- 2012/06/27 06:00
MHDA- 2012/06/27 06:00
CRDT- 2012/06/27 06:00
AID - 3789 [pii]
AID - 10.2500/ajra.2012.26.3789 [doi]
PST - aheadofprint
SO - Am J Rhinol Allergy. 2012 Jun 21.
PMID- 22384944
OWN - NLM
STAT- In-Process
DA - 20120515
IS - 1651-2251 (Electronic)
IS - 0001-6489 (Linking) VI - 132 Suppl 1
DP - 2012 Jun
TI - Endoscopic dacryocystorhinostomy without silicone stent.
PG - S77-81
AB - CONCLUSION: In nasolacrimal duct (NLD) obstruction patients that undergo
endoscopic dacryocystorhinostomy (DCR), creation of a patent rhinostomy with
adequate epithelialization can be accomplished without a stent. However, in
common canalicular obstruction patients, a silicone stent seems to have a
beneficial role and to bear more favorable results. OBJECTIVES: The aim of this
study was to evaluate the surgical outcome of endoscopic DCR without the use of a
silicone stent. METHODS: In all, 36 patients (41 eyes) who underwent endoscopic
DCR were enrolled in this study. The patients were classified into a DCR with
silicone stent group and a DCR without silicone stent group. Then each of the
groups was subdivided into common canalicular obstruction group and NLD
obstruction group. Surgical outcomes were evaluated by postoperative symptom
improvement and patency of the rhinostomy under nasal endoscopic exam. RESULTS:
The epiphora was improved in 84.2% of the silicone stent group and 81.8% of the
non-silicone stent group. Categorized by the level of obstruction, in common
canalicular obstruction, the success rate was 84.5% (11/13) in the silicone stent
group and 57.1% (4/7) in the no stent group. In NLD obstruction, the success rate
was 83.0% (5/6) in the silicone stent group and 93.3% (14/15) in the no stent
group.
AD - Department of Otorhinolaryngology - Head and Neck Surgery, Chungbuk National
University, Cheongju, Korea.
FAU - Yeon, Je Yeob AU - Yeon JY
FAU - Shim, Woo Sub
AU - Shim WS
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
DEP - 20120304
PL - England
TA - Acta Otolaryngol
JT - Acta oto-laryngologica
JID - 0370354
SB - IM
EDAT- 2012/03/06 06:00
MHDA- 2012/03/06 06:00
CRDT- 2012/03/06 06:00
PHST- 2012/03/04 [aheadofprint]
AID - 10.3109/00016489.2012.659754 [doi]
PST - ppublish
SO - Acta Otolaryngol. 2012 Jun;132 Suppl 1:S77-81. Epub 2012 Mar 4.
PMID- 22551366
OWN - NLM
STAT- MEDLINE
DA - 20120503
DCOM- 20120622 IS - 1744-5108 (Electronic)
IS - 0167-6830 (Linking)
VI - 31
IP - 3
DP - 2012 Jun
TI - A cadaveric study of the morphometric relationships and bony composition of the
caucasian nasolacrimal fossa.
PG - 159-61
AB - AIMS: To describe the morphometric relationships and bony composition of the
nasolacrimal fossa in a Caucasian population with particular reference to the
lacrimo-maxillary suture (LMS). METHODS: Forty-seven orbits from 24 formalin
fixed cadavers were exenterated. Morphometric measurements were taken between
anatomical landmarks forming the lacrimal fossa on the medial orbital wall.
RESULTS: The mean recorded distance from the anterior lacrimal crest (ALC) to the
posterior lacrimal crest (PLC) and the LMS were 8.8 mm (+/- 1.6) and 4.3 mm (+/-
1.1), respectively. In 25.5% of the orbits the LMS was at the mid-vertical line
(MVL), defined as a line equidistant from the ALC and PLC. In 42.5% the LMS was
located anterior to the MVL toward the ALC. In 66% of the orbits the LMS was at
or within one standard deviation (SD) of the MVL. The LMS was >1 SD away from the
MVL toward the ALC and PLC in 19% and 15% of orbits, respectively. CONCLUSIONS:
In a quarter of the orbits in our Caucasian population the nasolacrimal fossa was
formed equally by the maxillary and lacrimal bones. However, in nearly a third of
the cases the LMS was located closer to the PLC, indicating predominance of the
thicker maxillary bone. This may result in greater difficulty in initiating the
surgical osteotomy when performing a dacryocystorhinostomy. These data contribute to our understanding of the variation in lacrimal fossa anatomy and encourage
further studies in different racial groups.
AD - Adnexal Service, Moorfields Eye Hospital, London, UK. [email protected]
FAU - Shams, Pari N
AU - Shams PN
FAU - Abed, Saif F
AU - Abed SF
FAU - Shen, Sunny
AU - Shen S
FAU - Adds, Philip J
AU - Adds PJ
FAU - Uddin, Jimmy M
AU - Uddin JM
LA - eng
PT - Journal Article
PL - England
TA - Orbit
JT - Orbit (Amsterdam, Netherlands)
JID - 8301221
SB - IM
MH - Cadaver
MH - *European Continental Ancestry Group
MH - Female
MH - Humans
MH - Male MH - Maxilla/*anatomy & histology
MH - Nasolacrimal Duct/*anatomy & histology
MH - Orbit/*anatomy & histology
EDAT- 2012/05/04 06:00
MHDA- 2012/06/23 06:00
CRDT- 2012/05/04 06:00
AID - 10.3109/01676830.2011.648809 [doi]
PST - ppublish
SO - Orbit. 2012 Jun;31(3):159-61.
PMID- 22645114
OWN - NLM
STAT- Publisher
DA - 20120530
IS - 1097-6817 (Electronic)
IS - 0194-5998 (Linking)
DP - 2012 May 29
TI - Mitomycin C-Enhanced Revision Endoscopic Dacryocystorhinostomy: A Prospective
Randomized Controlled Trial.
AB - Objectives. (1) To conduct an adequately powered randomized controlled trial
investigating the safety and efficacy of mitomycin C-enhanced revision endoscopic
dacryocystorhinostomy (DCR) and (2) to analyze causes of failure after primary
endoscopic DCR.Study Design. A randomized controlled study.Setting. General
hospital.Subjects and Methods. Seventy-six revision endoscopic DCRs were
randomized into 2 groups: endoscopic DCR with mitomycin (group I), where 0.5 mg/mL mitomycin C was applied for 10 minutes, and endoscopic DCR without
mitomycin (group II). Follow-up settings were done to document the patient's
subjective improvement, to judge ostium patency on irrigation, and to record any
complications.Results. Causes of failure in the original 92 patients included
canalicular obstruction (14%), small misplaced bony window (43%), very small
nasolacrimal stoma due to development of synechia (23%), and complete closure of
nasolacrimal stoma with tough fibrous tissue (63%). There was no significant
difference between the 2 groups in subjective and objective success rates and
adverse events. Group I demonstrated a significantly longer operative time and a
significantly lower number of debridement sessions (mean of 1.2 vs
1.9).Conclusions. Recurrent nasolacrimal duct obstruction after primary
endoscopic DCR is mainly due to reclosure of the nasolacrimal stoma with synechia
and fashioning of the small misplaced bony window. Mitomycin C does not increase
the success rate of revision endoscopic DCR. It is a safe procedure and may be of
value only in patients inaccessible to strict follow-up because it induces a
better healing profile in terms of mucosal recovery, wound healing, and less need
for debridement sessions.
AD - Otolaryngology and Head & Neck Surgery, Tanta University Hospitals, Tanta, Egypt.
AU - Ragab SM
AU - Elsherif HS
AU - Shehata EM
AU - Younes A
AU - Gamea AM
LA - ENG
PT - JOURNAL ARTICLE DEP - 20120529
TA - Otolaryngol Head Neck Surg
JT - Otolaryngology--head and neck surgery : official journal of American Academy of
Otolaryngology-Head and Neck Surgery
JID - 8508176
EDAT- 2012/05/31 06:00
MHDA- 2012/05/31 06:00
CRDT- 2012/05/31 06:00
AID - 0194599812450280 [pii]
AID - 10.1177/0194599812450280 [doi]
PST - aheadofprint
SO - Otolaryngol Head Neck Surg. 2012 May 29.
PMID- 22623114
OWN - NLM
STAT- Publisher
DA - 20120524
IS - 1435-702X (Electronic)
IS - 0721-832X (Linking)
DP - 2012 May 24
TI - Success rate and complications of endonasal dacryocystorhinostomy with
unciformectomy.
AB - BACKGROUND: Endonasal dacryocystorhinostomy (DCR) has been widely used to treat
nasolacrimal duct obstruction. Here, we evaluated the anatomical advantages of
the uncinate process as a landmark and to study the effect of unciformectomy on success rate and complications of endonasal DCR . METHODS: In total, 288 eyes of
265 adult patients who underwent endonasal DCR between January 2003 and February
2010 were reviewed retrospectively. The eyes were classified into two groups,
according to whether unciformectomy was performed or not. All surgical procedures
and surgical indications were the same except unciformectomy and endonasal DCR
was performed by one surgeon. Unciformectomy was performed by resecting the
anterior part of uncinate process. RESULTS: One hundred and eighty-six eyes of
168 patients received endonasal DCR with unciformectomy, and 102 eyes of 97
patients received endonasal DCR alone. The average success rate of endonasal DCR
with unciformectomy was 97.8 % and that of endonasal DCR alone was 90.2 %, with
statistically significant difference (Student's t-test, p-value < 0.05). There
were 14 eyes with post-operative nasolacrimal obstruction, caused by granuloma in
five eyes, intranasal synechia in two eyes, membranous obstruction in six eyes,
and canalicular stenosis in one eye. There were no serious complications such as
orbital fat prolapse, cerebrospinal fluid leak, or delayed hemorrhage.
CONCLUSIONS: Anterior resection of the uncinate process gives improved access to
the lacrimal bone by exposing the medial aspect of the lacrimal fossa and forming
the precise location of the osteotomy on the lacrimal bone during endonasal DCR.
Thus, the uncinate process can be used as an anatomical landmark for endonasal
DCR. The unciformian endonasal DCR improves operation success rate by allowing
access to the large space of the nasal cavity and reducing the synechiae of the
nasal cavity.
AD - Department of Ophthalmology, Busan Paik Hospital, Inje University Medical
College, Gaegum-dong, Busanjin-gu, Busan, 633-165, Korea, [email protected].
AU - Yang JW AU - Oh HN
LA - ENG
PT - JOURNAL ARTICLE
DEP - 20120524
TA - Graefes Arch Clin Exp Ophthalmol
JT - Graefe's archive for clinical and experimental ophthalmology = Albrecht von
Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
EDAT- 2012/05/25 06:00
MHDA- 2012/05/25 06:00
CRDT- 2012/05/25 06:00
PHST- 2011/10/08 [received]
PHST- 2012/02/27 [accepted]
PHST- 2012/02/21 [revised]
PHST- 2012/05/24 [aheadofprint]
AID - 10.1007/s00417-012-1992-x [doi]
PST - aheadofprint
SO - Graefes Arch Clin Exp Ophthalmol. 2012 May 24.
PMID- 22581634
OWN - NLM
STAT- Publisher
DA - 20120514
IS - 1097-6817 (Electronic)
IS - 0194-5998 (Linking) DP - 2012 May 11
TI - Endoscopic Dacryocystorhinostomy with Double Posteriorly Based Nasal and Lacrimal
Flaps: A Prospective Randomized Controlled Trial.
AB - Objectives. To conduct the first prospective randomized controlled trial
assessing and comparing the safety and efficacy of endoscopic
dacryocystorhinostomy (DCR) with double posteriorly based nasal and lacrimal
flaps to conventional endoscopic DCR in adult patients with acquired complete
nasolacrimal obstruction.Study Design. A prospective randomized controlled
study.Setting. General hospital.Subjects and Methods. Seventy-four adult patients
with a total of 80 procedures were recruited to undergo endoscopic DCR. They were
prospectively equally randomized into 2 groups: endoscopic DCR with flaps (group
I) and conventional endoscopic DCR (group II). Regular follow-up settings were
done to document the patient's subjective improvement, judge ostium patency on
irrigation, and record any complications.Results. Endoscopic DCR with flaps had a
higher (92.1%) but nonsignificant difference in success rate when compared with
conventional endoscopic DCR (87.4%). There was no significant difference between
the 2 techniques in operative time, adverse events, and tolerability of the
technique to be done under local anesthesia with minimal sedation. Group I
demonstrated a significantly lower number of debridement sessions than did group
II.Conclusion. Endoscopic DCR with double posteriorly based nasal and lacrimal
flaps provides a viable alternative to conventional endoscopic DCR in managing
acquired nasolacrimal duct obstructions in adults. It has a comparable success
rate, operative time, and safety profile, with a suggestion of a better healing
profile in terms of mucosal recovery, wound healing, and less need for
debridement sessions. AD - Department of Otolaryngology and Head & Neck Surgery, Tanta University Hospitals,
Tanta, Egypt.
AU - Khalifa MA
AU - Ragab SM
AU - Saafan ME
AU - El-Guindy AS
LA - ENG
PT - JOURNAL ARTICLE
DEP - 20120511
TA - Otolaryngol Head Neck Surg
JT - Otolaryngology--head and neck surgery : official journal of American Academy of
Otolaryngology-Head and Neck Surgery
JID - 8508176
EDAT- 2012/05/15 06:00
MHDA- 2012/05/15 06:00
CRDT- 2012/05/15 06:00
AID - 0194599812447759 [pii]
AID - 10.1177/0194599812447759 [doi]
PST - aheadofprint
SO - Otolaryngol Head Neck Surg. 2012 May 11.
PMID- 22566177
OWN - NLM
STAT- Publisher
DA - 20120508 IS - 1434-4726 (Electronic)
IS - 0937-4477 (Linking)
DP - 2012 May 8
TI - Surgical success rate comparison in functional nasolacrimal duct obstruction:
simple lacrimal stent versus endoscopic versus external dacryocystorhinostomy.
AB - Silicone tube intubation (STI) has been known as a standard treatment modality
with functional nasolacrimal duct obstruction (FNDO). Recently,
dacryocystorhinostomy (DCR) is suggested for FNDO treatment. However, there are
no data for comparison according to the surgical types in FNDO patients. This
study aimed to compare success rates of three different lacrimal drainage
surgeries in FNDO patients. Consecutive patients (153 eyes) who were treated with
surgical intervention due to FNDO were analyzed. Patients were divided into three
groups according to the type of surgery undertaken: STI, endoscopic DCR
(Endo-DCR), and external DCR (Ext-DCR). Symptomatic improvements in epiphora were
evaluated using the following scoring system: 1, complete resolution (indicative
of success); 2, partial resolution; and 3, no resolution or worsening of the
condition. At months 3 and 6, the Endo-DCR group had the highest success rate
(84.4 and 81.3 %), but there were no statistically significant differences in
epiphora scoring among the patients. Epiphora was significantly improved after
surgery by week 2 in the Endo-DCR group (p = 0.0339) and by week 3 in the STI
group (p = 0.0161). There were no patients in the Endo- or Ext-DCR group with a
score of 3 at month 6, but 4 of 6 (3.7 %) in the STI group had score of 3 at
month 6 and underwent additional DCR for epiphora. Our results suggest that
Endo-DCR offers the highest success rates in FNDO treatments in terms of the
rapid and complete resolution of epiphora. AD - Department of Ophthalmology, Seoul St. Mary's Hospital, College of Medicine, The
Catholic University of Korea, #505, Banpo-dong, Seocho-gu, Seoul, 137-701, Korea.
AU - Cho WK
AU - Paik JS
AU - Yang SW
LA - ENG
PT - JOURNAL ARTICLE
DEP - 20120508
TA - Eur Arch Otorhinolaryngol
JT - European archives of oto-rhino-laryngology : official journal of the European
Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the
German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
JID - 9002937
EDAT- 2012/05/09 06:00
MHDA- 2012/05/09 06:00
CRDT- 2012/05/09 06:00
PHST- 2012/01/20 [received]
PHST- 2012/03/26 [accepted]
PHST- 2012/05/08 [aheadofprint]
AID - 10.1007/s00405-012-2014-7 [doi]
PST - aheadofprint
SO - Eur Arch Otorhinolaryngol. 2012 May 8.
PMID- 22247285
OWN - NLM STAT- MEDLINE
DA - 20120417
DCOM- 20120606
IS - 1468-2079 (Electronic)
IS - 0007-1161 (Linking)
VI - 96
IP - 5
DP - 2012 May
TI - A new lacrimal bypass tube fixation method to prevent tube displacement in
conjunctivodacryocystorhinostomy (CDCR).
PG - 674-8
AB - AIMS: To evaluate the efficacy of a new lacrimal bypass tube fixation technique
to the conjunctiva and caruncle, preventing postoperative displacement of the
tube in conjunctivodacryocystorhinostomies (CDCRs). METHODS: The authors
conducted 52 CDCR procedures by a new tube fixation technique using a 6-0 prolene
suture encircling the tube neck (encircling group). The suture was not removed
during the follow-up period. Over the same period, the authors carried out 51
CDCRs with tube fixation using a 5-0 vicryl suture with the purse string
procedure (purse string group) and 71 conventional CDCRs with tube fixation to
the skin using a 6-0 nylon suture (control group). Postoperative complications,
including dislodgement and tube length problems, were recorded. The three groups
were statistically compared. RESULTS: Among the 52 cases using the new fixation
technique, tube malpositions, including extrusions, had developed in only four
cases (7.7%) at 12 months after the operation. In the purse string and control
groups, the same complications developed in 11 (21.6%) and 22 cases (31.0%), respectively. A statistically significant difference between these groups was
detected (p=0.008). Other complications, such as conjunctival granulomas and tube
obstruction, developed postoperatively in four cases (8.0%) in the encircling
group, and this did not differ significantly from that in the other groups
(p=0.193). CONCLUSIONS: The authors believe that this encircling fixation
procedure can help in CDCRs for maintaining the location and orientation of the
tube during the early postoperative period.
AD - Department of Ophthalmology, Guro Hospital, Korea University College of Medicine,
97 Gurodong-gil, Guro-gu, Seoul 152-703, Korea.
FAU - Chang, Minwook
AU - Chang M
FAU - Baek, Sehyun
AU - Baek S
FAU - Lee, Tae Soo
AU - Lee TS
LA - eng
PT - Comparative Study
PT - Journal Article
DEP - 20120112
PL - England
TA - Br J Ophthalmol
JT - The British journal of ophthalmology
JID - 0421041
RN - 0 (Nylons)
RN - 34346-01-5 (Polyglactin 910) SB - IM
MH - Conjunctiva/*surgery
MH - Dacryocystorhinostomy/*methods
MH - Female
MH - Foreign-Body Migration/*prevention & control
MH - Glass
MH - Humans
MH - Intubation/*methods
MH - Lacrimal Duct Obstruction/*surgery
MH - Male
MH - Middle Aged
MH - Nasolacrimal Duct/surgery
MH - Nylons
MH - Polyglactin 910
MH - Postoperative Complications/*prevention & control
MH - Retrospective Studies
MH - *Suture Techniques
MH - Sutures
MH - Treatment Outcome
EDAT- 2012/01/17 06:00
MHDA- 2012/06/07 06:00
CRDT- 2012/01/17 06:00
PHST- 2012/01/12 [aheadofprint]
AID - bjophthalmol-2011-300860 [pii]
AID - 10.1136/bjophthalmol-2011-300860 [doi] PST - ppublish
SO - Br J Ophthalmol. 2012 May;96(5):674-8. Epub 2012 Jan 12.
PMID- 21725935
OWN - NLM
STAT- In-Process
DA - 20120511
IS - 1724-6016 (Electronic)
IS - 1120-6721 (Linking)
VI - 22
IP - 3
DP - 2012 May-Jun
TI - Effect of mitomycin C on success rate in dacryocystorhinostomy with silicone tube
intubation and improper flaps.
PG - 326-9
LID - 10.5301/ejo.5000007 [doi]
AB - PURPOSE: To assess the effect of mitomycin C on surgical success rate of
dacryocystorhinostomy and silicone intubation in patients with improper flaps.
METHODS: The study was a randomized clinical trial. The patients with indication
for dacryocystorhinostomy surgery with silicone intubation (inappropriate
lacrimal sac or nasal mucosal flaps during surgery and/or history of
dacryocystitis in the past 3 months) were randomly assigned to application of
mitomycin C (0.02%) on surgical flaps (group A) or a control group without
mitomycin C application (group B). Main outcome measures were subjective
symptomatic improvement and result of irrigation test at last follow-up visit. RESULTS: The study enrolled 88 patients (88 eyes); there were 42 patients in
group A and 46 patients in group B. There was an average follow-up of 10 months
(range 6-15 months) following surgery. Significant improvement (no tearing with
patent lacrimal system in irrigation) was observed in 31 patients (73.8%) in
group A and 32 patients (69.6%) in group B. There was no statistically
significant difference in no improvement (no change in tearing state and
obstruction in irrigation test), relative improvement (decreased tearing and
passage of fluid with force in irrigation test), and significant improvement rate
between the 2 groups of study (p>0.05). CONCLUSIONS: Application of mitomycin C
on surgical flaps during dacryocystorhinostomy surgery with silicone intubation
in patients with improper flaps has no proven beneficial effect on success rate
of surgery.
AD - Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences,
Tehran, Iran.
FAU - Eshraghy, Bahram
AU - Eshraghy B
FAU - Raygan, Firoozeh
AU - Raygan F
FAU - Tabatabaie, Syed Ziaeddin
AU - Tabatabaie SZ
FAU - Tari, Ali Sadeghi
AU - Tari AS
FAU - Kasaee, Abolfazl
AU - Kasaee A
FAU - Rajabi, Mohammad Taher AU - Rajabi MT
LA - eng
PT - Journal Article
PL - Italy
TA - Eur J Ophthalmol
JT - European journal of ophthalmology
JID - 9110772
SB - IM
EDAT- 2011/07/05 06:00
MHDA- 2011/07/05 06:00
CRDT- 2011/07/05 06:00
PHST- 2011/05/15 [accepted]
AID - B323DB12-89DC-424A-B139-E90012BFFA9F [pii]
AID - 10.5301/ejo.5000007 [doi]
PST - ppublish
SO - Eur J Ophthalmol. 2012 May-Jun;22(3):326-9. doi: 10.5301/ejo.5000007.
PMID- 22411166
OWN - NLM
STAT- In-Process
DA - 20120515
IS - 1613-2246 (Electronic)
IS - 0021-5155 (Linking)
VI - 56
IP - 3 DP - 2012 May
TI - Dacryoendoscopic observation and incidence of canalicular obstruction/stenosis
associated with S-1, an oral anticancer drug.
PG - 214-8
AB - PURPOSE: To report dacryoendoscopic observations and the incidence of lacrimal
obstruction/stenosis associated with S-1, an oral anticancer drug. DESIGN:
Retrospective, nonrandomized clinical trial. METHODS: A total of 52 patients (41
men, 11 women; age 42-93 years) who were prescribed the anticancer drug S-1 were
studied. Patients who suffered eye complaints following S-1 treatment underwent
ophthalmic examination, probing and lacrimal irrigation. Patients whose tear
meniscus was high or had abnormal lacrimal irrigation were evaluated by
dacryoendoscopy. RESULTS: Overall, 5 of 52 S-1-treated patients (9.6%)
experienced lacrimal passage stenosis/obstruction. One patient had punctal
stenosis, and four patients had canalicular obstruction/stenosis. The onset of
epiphora ranged from 2 to 8 months (4.4 +/- 2.2 months, mean +/- SD) after the
initiation of chemotherapy. CONCLUSIONS: Patients receiving S-1 treatment should
be evaluated for potential lacrimal disorders, particularly canalicular
obstruction/stenosis. Dacryoendoscopic observation is effective for the diagnosis
of this side effect.
AD - Sasaki Eye Clinic, 5-2-6 Mikuni-higashi, Mikuni, Sakai, 913-0016, Japan.
FAU - Sasaki, Tsugihisa
AU - Sasaki T
FAU - Miyashita, Hiroaki
AU - Miyashita H FAU - Miyanaga, Tamon
AU - Miyanaga T
FAU - Yamamoto, Katsushi
AU - Yamamoto K
FAU - Sugiyama, Kazuhisa
AU - Sugiyama K
LA - eng
PT - Journal Article
DEP - 20120313
PL - Japan
TA - Jpn J Ophthalmol
JT - Japanese journal of ophthalmology
JID - 0044652
SB - IM
EDAT- 2012/03/14 06:00
MHDA- 2012/03/14 06:00
CRDT- 2012/03/14 06:00
PHST- 2011/05/16 [received]
PHST- 2012/01/25 [accepted]
PHST- 2012/03/13 [aheadofprint]
AID - 10.1007/s10384-012-0127-6 [doi]
PST - ppublish
SO - Jpn J Ophthalmol. 2012 May;56(3):214-8. Epub 2012 Mar 13.
PMID- 22534704 OWN - NLM
STAT- In-Process
DA - 20120426
IS - 1643-3750 (Electronic)
IS - 1234-1010 (Linking)
VI - 18
IP - 5
DP - 2012 May
TI - Comparison of postoperative pain and satisfaction after dacryocystorhinostomy in
patients operated on under local and general anesthesia.
PG - CR265-70
AB - BACKGROUND: There has been only 1 study on postoperative pain after external
dacryocystorhinostomy (DCR) that compared pain between 2 groups of patients; 1
group received local anesthesia and the other received general anesthesia. To
further characterize the relationship between these 2 types of anesthesia and
postoperative pain, we designed a study in which a single patient received these
2 different anesthesia modalities for a short interval on 2 different sides.
MATERIAL/METHODS: There were 50 participants in this study. External DCR was
performed on the same participant on both sides using local anesthesia on 1 side
and general anesthesia on the other. Postoperative pain was measured using the
visual analogue scale (VAS), and localization and timing of pain were reported by
the participants. Postoperative nausea and vomiting (PONV) were documented if
present. RESULTS: Pain levels were significantly higher with general anesthesia 3
hours post-surgery, and 6 hours post-surgery the pain remains higher following
general anesthesia but is borderline insignificant (p=0.051). However, 12 hours post-surgery, there is no significant difference in the pain level (p=0.240).
There was no significant difference in the localization of pain with local and
general anesthesia. Postoperative nausea is significantly more frequent after
general anesthesia, and vomiting only occurs with general anesthesia. Local
anesthesia was preferred by 94% of the participants (47 out of 50). CONCLUSIONS:
The vast majority of patients in our study who have undergone both GA and LA DCR
would choose LA again, providing a compelling case for use of the LA technique.
AD - Faculty of Medicine, University of Belgrade, Serbia. [email protected]
FAU - Knezevic, Miroslav M
AU - Knezevic MM
FAU - Vlajkovic, Gordana P
AU - Vlajkovic GP
FAU - Stojkovic, Milenko Z
AU - Stojkovic MZ
FAU - Rasic, Dejan M
AU - Rasic DM
FAU - Stankovic, Branislav R
AU - Stankovic BR
FAU - Bozic, Marija M
AU - Bozic MM
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PL - Poland
TA - Med Sci Monit JT - Medical science monitor : international medical journal of experimental and
clinical research
JID - 9609063
SB - IM
EDAT- 2012/04/27 06:00
MHDA- 2012/04/27 06:00
CRDT- 2012/04/27 06:00
AID - 882730 [pii]
PST - ppublish
SO - Med Sci Monit. 2012 May;18(5):CR265-70.
PMID- 22283720
OWN - NLM
STAT- In-Process
DA - 20120323
IS - 1460-2202 (Electronic)
IS - 0271-3683 (Linking)
VI - 37
IP - 4
DP - 2012 Apr
TI - Assessment of patient satisfaction following external versus transcanalicular
dacryocystorhinostomy with a diode laser and evaluation if change in quality of
life after simultaneous bilateral surgery in patients with bilateral nasolacrimal
duct obstruction.
PG - 286-92 AB - AIM: To compare patient satisfaction and experience after external
dacryocystorhinostomy (EX-DCR) versus transcanalicular DCR (TC-DCR) with a diode
laser and to evaluate the change in quality of life following simultaneous
bilateral DCR. METHODS: Prospective evaluation of 38 eyes of 19 patients with
bilateral nasolacrimal duct obstruction (NLDO) who underwent TC-DCR for the right
eye (Group 1) and EX-DCR for the left eye (Group 2) simultaneously. The
subjective outcomes (tearing, irritation, pain, discharge, swelling, and change
in visual acuity) of the patients in the two groups at 1 week, 1 month, and 3
months were compared using a questionnaire. The patients answered the questions
in the Glascow Benefit Inventory (GBI) to evaluate the change in quality of life
after simultaneous bilateral DCR at 1 month and 3 months. The symptom scores were
compared between Group 1 and Group 2 using a Mann-Whitney test. The Wilcoxon test
was used for the comparison of intragroup differences. RESULTS: The overall
symptom scores significantly improved in both groups. The overall symptom score
and six ocular symptom scores did not show a significant difference between the
two groups at 1 week, 1 month, and 3 months. Quality of life of the patients
significantly improved after simultaneous bilateral surgery according to GBI
scoring at 1 month and 3 months. CONCLUSION: The subjective outcomes
significantly improved in similar ways after successful TC-DCR and EX-DCR during
the early postoperative period. Our study shows that simultaneous bilateral DCR
confers a significant quality of life improvement.
AD - Department of Ophthalmology, Istanbul University, Istanbul Faculty of Medicine,
Istanbul, Turkey. [email protected]
FAU - Yeniad, Baris
AU - Yeniad B FAU - Uludag, Gunay
AU - Uludag G
FAU - Kozer-Bilgin, Lale
AU - Kozer-Bilgin L
LA - eng
PT - Journal Article
DEP - 20120127
PL - England
TA - Curr Eye Res
JT - Current eye research
JID - 8104312
SB - IM
EDAT- 2012/01/31 06:00
MHDA- 2012/01/31 06:00
CRDT- 2012/01/31 06:00
PHST- 2012/01/27 [aheadofprint]
AID - 10.3109/02713683.2012.658488 [doi]
PST - ppublish
SO - Curr Eye Res. 2012 Apr;37(4):286-92. Epub 2012 Jan 27.
PMID- 22496009
OWN - NLM
STAT- In-Process
DA - 20120412
IS - 1439-3999 (Electronic) IS - 0023-2165 (Linking)
VI - 229
IP - 4
DP - 2012 Apr
TI - Mucosal excision instead of fashioning nasolacrimal mucosae flaps during external
dacryocystorhinostomy: a pilot study.
PG - 387-90
AB - BACKGROUND: To report results of a simplified external dacryocytorhinostomy
procedure in which nasal and lacrimal sac mucosal flaps are simply removed
instead of being sutured together. PATIENTS AND METHODS: Design: Retrospective
non-comparative case-series study. Participants: Fourteen consecutive outpatients
patients undergoing external dacryocytorhinostomy. Intervention: Modified and
simplified transcutaneous external dacryocytorhinostomy where basically the
lacrimal sac and the nasal mucosae are widely excised in front of DCR's osteotomy
instead of being used to fashion nasolacrimal flaps. Outcome: Assessment of
dacryocytorhinostomy anatomical patency by syringing and patient's
self-perception of epiphora symptoms improvement about twelve weeks and one year
after surgery, as well as patient's report of ocular air-reflux during Valsalva
maneuver a year after surgery. RESULTS: Syringing showed anatomic patency in 93 %
and 92 % of patients twelve weeks (mean +/- SD: 12 weeks +/- 6 weeks) and one
year (15 months +/- 3 months) after surgery, respectively. One year after
surgery, 62 % of patients reported ocular air-reflux. Twelve weeks and one year
after surgery, mean symptom improvement was 82 % +/- 17 % and 79 % +/- 29 %,
respectively. Furthermore, 79 % and 85 % of patients reported a postoperative
improvement of their symptoms greater or equal to 80 % after twelve weeks and one year, respectively. CONCLUSIONS: Removing lacrimal sac and nasal mucosae in front
of the osteotomy did not appear to have a major negative impact on the outcome of
the external dacryocytorhinostomy. The findings of this pilot study need to be
confirmed by a larger prospective trial.
CI - (c) Georg Thieme Verlag KG Stuttgart . New York.
AD - Leonhard's Praxis-Clinic, Basel, Switzerland. [email protected]
FAU - Haefliger, I O
AU - Haefliger IO
FAU - Tschopp, M
AU - Tschopp M
FAU - Pimentel, A-R
AU - Pimentel AR
LA - eng
PT - Journal Article
DEP - 20120411
PL - Germany
TA - Klin Monbl Augenheilkd
JT - Klinische Monatsblatter fur Augenheilkunde
JID - 0014133
SB - IM
EDAT- 2012/04/13 06:00
MHDA- 2012/04/13 06:00
CRDT- 2012/04/13 06:00
PHST- 2012/04/11 [epublish]
AID - 10.1055/s-0031-1299433 [doi] PST - ppublish
SO - Klin Monbl Augenheilkd. 2012 Apr;229(4):387-90. Epub 2012 Apr 11.
PMID- 22489849
OWN - NLM
STAT- MEDLINE
DA - 20120411
DCOM- 20120615
IS - 1744-5108 (Electronic)
IS - 0167-6830 (Linking)
VI - 31
IP - 2
DP - 2012 Apr
TI - A comparison of external and endonasal dacryocystorhinostomy in regard to patient
satisfaction and cost.
PG - 67-76
AB - BACKGROUND: Definitive treatment of nasolacrimal duct obstruction is with
external or endonasal dacryocystorhinostomy (DCR). Recent trials suggest surgical
equivalency between techniques. We sought to compare alternative outcomes of DCR
techniques in terms of quality of life and cost. METHODS: This study was a
multicentre prospective nonrandomized case series comparing adult patients
treated with external or endonasal DCR. Groups were allocated according to DCR
technique. Participation did not affect treatment choice. The Glasgow Benefit
Inventory (GBI) was utilized to compare postoperative quality of life, and an
activity-based costing (ABC) method used to estimate costs of the two techniques. Surgical data were also collected. A minimum of 3 months follow-up was observed.
RESULTS: Seventy-seven patients were included--37 external and 40 endonasal. Both
techniques resulted in positive health status change, with mean GBI scores of
+16.1 for external DCR and +24.1 for endonasal (p = 0.18). Using an ABC method,
the operative costs of external DCR were less than endonasal at $715.79 AUD and
$932.52 AUD respectively. CONCLUSIONS: This trial suggests that external and
endonasal DCR produce comparable outcomes in terms of postoperative quality of
life, with external DCR resulting in lower operative costs.
AD - Department of Ophthalmology, Alfred Hospital, Prahran, Australia.
FAU - Hii, Belinda W
AU - Hii BW
FAU - McNab, Alan A
AU - McNab AA
FAU - Friebel, Justin D
AU - Friebel JD
LA - eng
PT - Comparative Study
PT - Journal Article
PT - Multicenter Study
PL - England
TA - Orbit
JT - Orbit (Amsterdam, Netherlands)
JID - 8301221
SB - IM MH - Adult
MH - Aged
MH - Aged, 80 and over
MH - Dacryocystorhinostomy/*economics/*methods
MH - Female
MH - *Health Care Costs
MH - Humans
MH - Lacrimal Duct Obstruction/*economics/surgery
MH - Male
MH - Middle Aged
MH - Nasolacrimal Duct/*surgery
MH - *Patient Satisfaction
MH - Prospective Studies
MH - Quality of Life
MH - Questionnaires
MH - Sickness Impact Profile
MH - Treatment Outcome
EDAT- 2012/04/12 06:00
MHDA- 2012/06/16 06:00
CRDT- 2012/04/12 06:00
AID - 10.3109/01676830.2011.648803 [doi]
PST - ppublish
SO - Orbit. 2012 Apr;31(2):67-76.
PMID- 21392851 OWN - NLM
STAT- MEDLINE
DA - 20111129
DCOM- 20120403
IS - 1532-818X (Electronic)
IS - 0196-0709 (Linking)
VI - 33
IP - 1
DP - 2012 Jan-Feb
TI - Significance of adjunctive mitomycin C in endoscopic dacryocystorhinostomy.
PG - 47-50
AB - PURPOSE: The purpose of this study is to observe the effect of intraoperative
topical application of mitomycin C (MMC) on the results of endoscopic
dacryocystorhinostomy. DESIGN: This is a prospective, randomized, controlled,
single-blind study. SETTINGS: Hospitalized treatment was done in a tertiary
medical college hospital and research center that deals with a predominantly
rural population. PATIENTS: Patients with primary acquired postsaccal obstruction
causing chronic dacryocystitis were considered. METHODS: A total of 38 patients
were randomized into either a mitomycin group or a control group. Both of these
groups were subjected to an identical surgical procedure, except that 0.2 mg/dL
of MMC was used in the mitomycin group, whereas normal saline was used in the
control group. The follow-up period was at least 6 months. An asymptomatic
patient with a visible stoma at nasendoscopy and free flow of saline into the
nose with lacrimal syringing after 6 months after surgery was used as criteria
for defining a successful result. RESULTS: The success rate was 82.3% when MMC was used and 85.7% among the controls (P > .05). Granulations, adhesions, and
obliterative sclerosis occurred in a similar number of patients of both groups.
However, granulations and adhesions did not have a bearing on the success rate in
either group. CONCLUSION: Mitomycin C did not appear to influence the occurrence
of granulations, synechiae, or obliterative sclerosis, nor did it alter the
success rate significantly.
CI - Copyright (c) 2012 Elsevier Inc. All rights reserved.
AD - Department of Otorhinolaryngology, R.L. Jalappa Hospital and Research Centre, Sri
Devaraj Urs Medical College, Sri Devaraj Urs Academy of Higher Education, Tamaka,
Kolar, India. [email protected]
FAU - Prasannaraj, Thomas
AU - Prasannaraj T
FAU - Kumar, B Y Praveen
AU - Kumar BY
FAU - Narasimhan, Indira
AU - Narasimhan I
FAU - Shivaprakash, K V
AU - Shivaprakash KV
LA - eng
PT - Journal Article
PT - Randomized Controlled Trial
DEP - 20110309
PL - United States
TA - Am J Otolaryngol
JT - American journal of otolaryngology JID - 8000029
RN - 0 (Alkylating Agents)
RN - 50-07-7 (Mitomycin)
SB - IM
MH - Administration, Topical
MH - Adolescent
MH - Adult
MH - Alkylating Agents/*administration & dosage
MH - Combined Modality Therapy
MH - Dacryocystitis/*drug therapy/*surgery
MH - Dacryocystorhinostomy/*methods
MH - Endoscopy/*methods
MH - Female
MH - Humans
MH - Intraoperative Period
MH - Male
MH - Middle Aged
MH - Mitomycin/*administration & dosage
MH - Prospective Studies
MH - Single-Blind Method
MH - Treatment Outcome
EDAT- 2011/03/12 06:00
MHDA- 2012/04/04 06:00
CRDT- 2011/03/12 06:00
PHST- 2010/08/24 [received] PHST- 2010/12/16 [revised]
PHST- 2011/01/24 [accepted]
PHST- 2011/03/09 [aheadofprint]
AID - S0196-0709(11)00023-8 [pii]
AID - 10.1016/j.amjoto.2011.01.001 [doi]
PST - ppublish
SO - Am J Otolaryngol. 2012 Jan-Feb;33(1):47-50. Epub 2011 Mar 9.
PMID- 22082600
OWN - NLM
STAT- MEDLINE
DA - 20120120
DCOM- 20120325
IS - 1537-2677 (Electronic)
IS - 0740-9303 (Linking)
VI - 28
IP - 1
DP - 2012 Jan
TI - External dacryocystorhinostomy outcomes in sarcoidosis patients.
PG - 47-9
AB - PURPOSE: To determine surgical outcomes after external dacryocystorhinostomy
(DCR) surgery in patients with sarcoidosis. METHODS: We retrospectively reviewed
the charts of all patients with sarcoidosis who underwent external DCR surgery
between January 2001 and January 2010. Clinical data reviewed included patient
demographics, immunosuppressive therapies, biopsy results, use of intraoperative triamcinolone, and postoperative outcomes and complications. Success was defined
as resolution of epiphora. RESULTS: External DCR was performed on 13 sides of 9
patients with sarcoidosis. Four patients were systemically immunosuppressed with
methotrexate or plaquenil, and 4 patients used inhaled corticosteroids only.
Intraoperative biopsy in 10 cases (9 patients) revealed non-necrotizing
granulomatous inflammation (8 cases) and chronic inflammation (2 cases). Silicone
stents were removed at a mean of 2.9 months. Initial DCR surgery was successful
in 10 of 13 (87%) surgeries with an average follow up of 31 months (range, 14 to
48 months). None of the 5 surgeries (4 patients) with intralesional triamcinolone
injections failed, compared with 3 of 8 (38%) surgeries without intralesional
triamcinolone. Of the 3 failures, 2 early failures (3 months) were successfully
treated with balloon catheter dilation. In the one patient with a late failure
(47 months), subsequent balloon catheter dilation failed. All 3 patients who
experienced failures used inhaled corticosteroids only. In contrast, 4 of the 6
patients with successful surgery were systemically immunosuppressed.
Complications such as punctal erosion, wound necrosis, or cerebrospinal fluid
leak did not occur. CONCLUSIONS: External DCR surgery successfully treats
nasolacrimal duct obstruction associated with sarcoidosis. Intralesional
triamcinolone may improve the success rate without added complications. Long-term
success may be less in patients not receiving systemic immunosuppressive therapy.
AD - Kellogg Eye Center, University of Michigan, Ann Arbor, Michigan, USA.
FAU - Lee, Brian J
AU - Lee BJ
FAU - Nelson, Christine C
AU - Nelson CC FAU - Lewis, Craig D
AU - Lewis CD
FAU - Perry, Julian D
AU - Perry JD
LA - eng
PT - Journal Article
PL - United States
TA - Ophthal Plast Reconstr Surg
JT - Ophthalmic plastic and reconstructive surgery
JID - 8508431
RN - 0 (Anti-Inflammatory Agents)
RN - 0 (Immunosuppressive Agents)
RN - 124-94-7 (Triamcinolone)
SB - IM
MH - Adult
MH - Anti-Inflammatory Agents/therapeutic use
MH - Dacryocystorhinostomy/*methods
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - Immunosuppressive Agents/therapeutic use
MH - Lacrimal Duct Obstruction/drug therapy/etiology/*surgery
MH - Male
MH - Middle Aged
MH - Nasolacrimal Duct/*surgery MH - Perioperative Care
MH - Postoperative Complications
MH - Retrospective Studies
MH - Sarcoidosis/*complications/drug therapy
MH - Triamcinolone/therapeutic use
EDAT- 2011/11/16 06:00
MHDA- 2012/03/27 06:00
CRDT- 2011/11/16 06:00
AID - 10.1097/IOP.0b013e3182364ad2 [doi]
PST - ppublish
SO - Ophthal Plast Reconstr Surg. 2012 Jan;28(1):47-9.
PMID- 22153640
OWN - NLM
STAT- MEDLINE
DA - 20111213
DCOM- 20120330
IS - 0008-4182 (Print)
IS - 0008-4182 (Linking)
VI - 46
IP - 6
DP - 2011 Dec
TI - A meta-analysis of primary dacryocystorhinostomy with and without silicone
intubation.
PG - 521-7 AB - OBJECTIVE: To examine possible differences in success rates of primary
dacryocystorhinostomy (DCR) with and without silicone intubation, and to find out
whether the use of silicone tubes is beneficial. DESIGN: A literature search was
conducted in the PubMed, EMBASE, and Cochrane Controlled Trials Register to
identify potentially relevant controlled trials. METHODS: Language was restricted
to English. The surgical techniques were categorized into external DCR (EX-DCR),
endonasal laser-assisted DCR (LA-DCR), and nonlaser endoscopic endonasal DCR
techniques (EN-DCR). The main outcome measure was success rates after DCR-with
and DCR-without silicone intubation. The statistical analysis was carried out
using a RevMan 5.0 software. RESULTS: Of 188 retrieved trials from the electronic
database, 9 trials (5 randomized controlled trials and 4 cohort studies)
involving 514 cases met our inclusion criteria. There was no statistically
significant heterogeneity between the studies. The pooled risk ratio was 0.99,
with a 95% confidence interval (0.91-1.08). There was no significant difference
in the success rates between the DCR with and without silicone intubation (p =
0.81). Sensitivity analysis and subgroups analyses suggested that the result was
comparatively reliable. CONCLUSIONS: Based on this meta-analysis that included 5
randomized controlled trials and 4 cohort studies, no benefit was found for
silicone tube intubation in primary DCR. Further well-organized, prospective,
randomized studies involving larger patient numbers are required.
CI - Copyright (c) 2011 Canadian Ophthalmological Society. Published by Elsevier Inc.
All rights reserved.
AD - The Affiliated Eye Hospital of Wenzhou Medical College, Zhejiang, China.
FAU - Feng, Yi-Fan
AU - Feng YF FAU - Cai, Jian-Qiu
AU - Cai JQ
FAU - Zhang, Jia-Yu
AU - Zhang JY
FAU - Han, Xiao-Hui
AU - Han XH
LA - eng
PT - Journal Article
PT - Meta-Analysis
PL - England
TA - Can J Ophthalmol
JT - Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
JID - 0045312
RN - 0 (Silicones)
SB - IM
MH - *Dacryocystorhinostomy
MH - Databases, Factual
MH - Humans
MH - *Intubation
MH - Lacrimal Duct Obstruction/*therapy
MH - Nasolacrimal Duct/*surgery
MH - Randomized Controlled Trials as Topic
MH - Silicones
MH - *Stents
MH - Treatment Outcome EDAT- 2011/12/14 06:00
MHDA- 2012/03/31 06:00
CRDT- 2011/12/14 06:00
PHST- 2011/01/29 [received]
PHST- 2011/07/08 [revised]
PHST- 2011/09/07 [accepted]
AID - S0008-4182(11)00218-3 [pii]
AID - 10.1016/j.jcjo.2011.09.008 [doi]
PST - ppublish
SO - Can J Ophthalmol. 2011 Dec;46(6):521-7.
PMID- 22185749
OWN - NLM
STAT- MEDLINE
DA - 20111221
DCOM- 20120509
IS - 1945-8932 (Electronic)
IS - 1945-8932 (Linking)
VI - 25
IP - 6
DP - 2011 Nov-Dec
TI - Mitomycin C in revision endoscopic dacryocystorhinostomy: a prospective
randomized study.
PG - 425-8
AB - BACKGROUND: Endoscopic dacryocystorhinostomy (EN-DCR) is an effective and safe procedure when treating saccal and postsaccal nasolacrimal duct obstruction.
However, sometimes scarring of the rhinostomy site caused by fibrosis may occur,
particularly in revision operations. The application of intraoperative mitomycin
C (MMC), an antiproliferative agent, has been introduced as one possible
technique to improve the outcome. We conducted a prospective, randomized study to
evaluate if the use of MMC improves the success in endonasal revision DCR
procedure. METHODS: Thirty revision EN-DCR procedures were performed during
2004-2010. The patients were randomized into two study groups, according to
whether the intraoperative MMC was used or not. The technique of EN-DCR procedure
in both groups was the same, but in the MMC group, at the end of the procedure a
piece of tampon soaked in MMC (0.4 mg/mL) was placed into the rhinostoma for 5
minutes. No silicone stents were inserted. The surgical outcome at the 6-month
follow-up visit was considered successful if the lacrimal sac irrigation
succeeded and if the patients' symptoms were relieved. RESULTS: The success rate
after revision EN-DCR with MMC was 93% and without MMC was 60%. The overall
success rate was 77%. The difference between the two groups was not statistically
significant (p = 0.08). The relief of the symptoms between groups in both the
Nasolacrimal Duct Obstruction Symptom Score and ocular symptoms was statistically
significant (p = 0.007 and p = 0.02, respectively). CONCLUSION: The results of
our study indicate that the application of intraoperative mitomycin C may improve
the outcome in revision EN-DCR.
AD - Department of Otorhinolaryngology, Institute of Clinical Medicine, Kuopio
University Hospital, and University of Eastern Finland, Finland.
FAU - Penttila, Elina
AU - Penttila E FAU - Smirnov, Grigori
AU - Smirnov G
FAU - Seppa, Juha
AU - Seppa J
FAU - Kaarniranta, Kai
AU - Kaarniranta K
FAU - Tuomilehto, Henri
AU - Tuomilehto H
LA - eng
PT - Journal Article
PT - Randomized Controlled Trial
PL - United States
TA - Am J Rhinol Allergy
JT - American journal of rhinology & allergy
JID - 101490775
RN - 0 (Antibiotics, Antineoplastic)
RN - 0 (Growth Inhibitors)
RN - 50-07-7 (Mitomycin)
SB - IM
MH - Aged
MH - Aged, 80 and over
MH - Antibiotics, Antineoplastic/*administration & dosage/adverse effects
MH - Cicatrix/*etiology/prevention & control
MH - *Dacryocystorhinostomy
MH - Endoscopy MH - Female
MH - Follow-Up Studies
MH - Growth Inhibitors/*administration & dosage/adverse effects
MH - Humans
MH - Intraoperative Care
MH - Lacrimal Duct Obstruction/complications/*drug therapy/surgery
MH - Male
MH - Middle Aged
MH - Mitomycin/*administration & dosage/adverse effects
MH - Postoperative Complications/etiology/prevention & control
MH - Prospective Studies
MH - Reoperation
MH - Treatment Outcome
EDAT- 2011/12/22 06:00
MHDA- 2012/05/10 06:00
CRDT- 2011/12/22 06:00
AID - 10.2500/ajra.2011.25.3676 [doi]
PST - ppublish
SO - Am J Rhinol Allergy. 2011 Nov-Dec;25(6):425-8.
PMID- 21681436
OWN - NLM
STAT- MEDLINE
DA - 20111028
DCOM- 20120201 IS - 1435-702X (Electronic)
IS - 0721-832X (Linking)
VI - 249
IP - 11
DP - 2011 Nov
TI - Monocanalicular versus bicanalicular intubation in the treatment of congenital
nasolacrimal duct obstruction.
PG - 1729-33
AB - BACKGROUND: To compare the success rate of monocanalicular intubation (MCI)
compared with bicanalicular silicone intubation (BCI) in congenital nasolacrimal
duct obstruction (CNLDO) in infants and toddlers. METHODS: In a prospective,
nonrandomized, comparative study, MCI (n = 35 eyes) through the inferior
canaliculus or BCI (n = 35 eyes) were performed under general anaesthesia in
children aged 10 to 36 months with CNLDO. The tubes were removed 3-4 months after
tube placement, and the children were followed up for 6 months after the removal
of tubes. Therapeutic success was defined as the fluorescein dye disappearance
test grade 0-1, corresponding with a complete resolution of previous symptoms.
Partial success was defined as improvement with some residual symptoms. RESULTS:
Complete and partial improvement was achieved in 31/35 (88.57%) in the BCI group
and 34/35 (97.14%) in the MCI group. The difference between the two groups was
not significant (p = 0.584). Complications occurred in both groups. Dislodgement
of the tube and premature removal was observed in four BCI cases, and loss of the
tube was observed twice in the MCI group. Canalicular slitting was observed in
five eyes in the BCI group. Granuloma pyogenicum observed in 2 cases with MCI
revealed a few weeks after the tube removal. Corneal erosion in the inferior medial quadrant was observed in one MCI eye and revealed in a few days after the
local treatment without tube removal. CONCLUSIONS: Both MCI and the BCI are
effective methods for treating CNLDO. MCI has the advantage of a lower incidence
of canalicular slit and easy placement.
AD - Department of Otolaryngology, University Hospital Ostrava, Ostrava, Czech
Republic. [email protected]
FAU - Kominek, Pavel
AU - Kominek P
FAU - Cervenka, Stanislav
AU - Cervenka S
FAU - Pniak, Tomas
AU - Pniak T
FAU - Zelenik, Karol
AU - Zelenik K
FAU - Tomaskova, Hana
AU - Tomaskova H
FAU - Matousek, Petr
AU - Matousek P
LA - eng
PT - Comparative Study
PT - Journal Article
DEP - 20110617
PL - Germany
TA - Graefes Arch Clin Exp Ophthalmol
JT - Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
RN - 0 (Silicone Elastomers)
RN - 2321-07-5 (Fluorescein)
SB - IM
MH - Anesthesia, General
MH - Child, Preschool
MH - Device Removal
MH - Female
MH - Fluorescein/metabolism
MH - Humans
MH - Infant
MH - Intubation/*methods
MH - Lacrimal Duct Obstruction/*congenital/physiopathology/*therapy
MH - Male
MH - Nasolacrimal Duct/*abnormalities/physiopathology
MH - Postoperative Complications
MH - Prospective Studies
MH - *Silicone Elastomers
MH - Treatment Outcome
PMC - PMC3203220
OID - NLM: PMC3203220
EDAT- 2011/06/18 06:00
MHDA- 2012/02/02 06:00
CRDT- 2011/06/18 06:00 PHST- 2010/11/08 [received]
PHST- 2011/04/15 [accepted]
PHST- 2011/02/08 [revised]
PHST- 2011/06/17 [aheadofprint]
AID - 10.1007/s00417-011-1700-2 [doi]
PST - ppublish
SO - Graefes Arch Clin Exp Ophthalmol. 2011 Nov;249(11):1729-33. Epub 2011 Jun 17.
PMID- 21632147
OWN - NLM
STAT- MEDLINE
DA - 20111107
DCOM- 20120305
IS - 1773-0597 (Electronic)
IS - 0181-5512 (Linking)
VI - 34
IP - 9
DP - 2011 Nov
TI - Pushed monocanalicular intubation. Pitfalls, deleterious side effects, and
complications.
PG - 597-607
AB - PURPOSE: To present our experience with pushed monocanalicular nasolacrimal
intubation in the management of 90 consecutive cases of nasolacrimal outflow
obstruction. MATERIALS AND METHOD: This paper reports a non-randomized study of
90 consecutive cases treated with a pushed Monoka intubation system (Masterka). A metal guide is placed inside a silicone tube rather than being attached at the distal end of the tube, as done with traditional pulled intubations. Three probe lengths are available: 30, 35, and 40 mm. SURGICAL PROCEDURE: The silicone stent was pushed into a punctum, canaliculus, and nasolacrimal duct by means of the guide. After passing through the valve of Hasner and reaching the nasal floor, the guide was then delicately withdrawn while remaining oriented along the axis of the lacrimal sac and duct. Throughout this phase, the anchoring plug was held in contact with the punctum. Three study groups were set up chronologically: group 1: endo-DCR procedures done with Masterka insertions under endoscopic observation. Group 2: Masterka insertions done with endoscopic guidance. Group 3: blind Masterka insertions without endoscopic guidance. The patients in groups 2 and 3 were selected on the information obtained by lacrimal probing. Only cases with mucosal nasolacrimal stenoses were included. All patients had surgery under general anesthesia with mechanically assisted ventilation (groups 1 and 2) or spontaneous ventilation (group 3). The anchoring plug was inserted into the punctum and vertical canaliculus, either by pulling on the probe (group 1) or using an inserting instrument. RESULTS: A total of 90 pushed Monoka intubations were done. Endoscopic examination (groups 1 and 2) demonstrated visually that the pushed intubation method was effective. In none of the 28 cases did the silicone bunch up when the guide was withdrawn. DEGREE OF DIFFICULTY: This was dependent upon proper selection for pushed Monoka intubation; the length of the probe and confirmation that there no false passage was created. The pushed intubation technique was only slightly more difficult than a simple lacrimal probing. The average operating time, excluding the anesthetic procedures, was respectively 5 min (group 2) and 4 min (group 3). COMPLICATIONS DURING SURGERY: There were no anesthetic or general problems observed in the three groups. Epistaxis was also
not noted. POSTOPERATIVE COMPLICATIONS: Fifteen percent (13/90). The 13
complications noted were: two cases of canaliculitis, one intracanalicular
migration, eight probes that disappeared, one keratitis, and one case of
involuntary removal by the patient. DELETERIOUS SIDE EFFECTS: Tearing with the
probe was in place was noted in 21.1% of the cases (19/90). This tearing
disappeared as soon as the probe was removed in 50% of these cases (10/19).
FUNCTIONAL RESULTS: Overall, the success rate (absence of epiphora, absence of
mucous discharge) was 90% (81/90) with an average follow-up period of 19 weeks
(Range, 1 day to 60 weeks). Two cases were lost to follow-up at day 1 and day 7.
Group 1: 90.9% (20/22 cases; average age: 65 years, with an average follow-up
period of 24 weeks). Group 2: 100% (6/6 cases; average age: 3.1 years, with an
average follow-up period of 14 weeks). Group 3: 88.3% (53/60 cases excluding the
two cases that were lost to follow-up; mean age: 2.3 years, with an average
follow-up period of 16 weeks). CONCLUSIONS: From a technical perspective, pushed
nasolacrimal intubation is much simpler than the traditional pulled types of
nasolacrimal intubation. The anesthetic procedure required is the same as that
for a late probing procedure, but the functional results are better. The Masterka
is an alternative to simple late probing in the treatment of mucosal nasolacrimal
stenoses in patients of over 12 months of age.
CI - Copyright A(c) 2011 Elsevier Masson SAS. All rights reserved.
AD - Department of Ophthalmology, Hotel-Dieu de Paris, University of Paris VI -
Medical School, 1, place du Parvis-Notre-Dame, 75181 Paris cedex 04, France.
FAU - Fayet, B AU - Fayet B
FAU - Racy, E
AU - Racy E
FAU - Ruban, J-M
AU - Ruban JM
FAU - Katowitz, J
AU - Katowitz J
LA - eng
PT - Clinical Trial
PT - Journal Article
DEP - 20110601
PL - France
TA - J Fr Ophtalmol
JT - Journal francais d'ophtalmologie
JID - 7804128
SB - IM
MH - Adult
MH - Aged
MH - Child
MH - Child, Preschool
MH - Endoscopy/adverse effects/methods
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - Infant MH - Intubation/*adverse effects/*methods
MH - Lacrimal Duct Obstruction/epidemiology/etiology/*therapy
MH - Male
MH - Mechanical Processes
MH - Middle Aged
MH - Models, Biological
MH - *Nasolacrimal Duct/pathology
MH - Postoperative Complications/epidemiology/etiology
MH - Stents/adverse effects
EDAT- 2011/06/03 06:00
MHDA- 2012/03/06 06:00
CRDT- 2011/06/03 06:00
PHST- 2010/11/15 [received]
PHST- 2011/02/16 [revised]
PHST- 2011/02/18 [accepted]
PHST- 2011/06/01 [aheadofprint]
AID - S0181-5512(11)00159-8 [pii]
AID - 10.1016/j.jfo.2011.02.008 [doi]
PST - ppublish
SO - J Fr Ophtalmol. 2011 Nov;34(9):597-607. Epub 2011 Jun 1.
PMID- 21353409
OWN - NLM
STAT- MEDLINE
DA - 20110418 DCOM- 20110830
IS - 1879-1476 (Electronic)
IS - 0385-8146 (Linking)
VI - 38
IP - 5
DP - 2011 Oct
TI - Primary diffuse large B-cell lymphoma of the lacrimal sac simulating chronic
dacryocystitis.
PG - 643-5
AB - Primary diffuse large B-cell lymphoma of the lacrimal sac is rare. Herein we
report a 55-year-old female presented with epiphora in the right eye. Distention
of the lacrimal sac secondary to nasolacrimal duct obstruction was observed. She
was scheduled for external dacryocystorinostomy for the next month. When she came
for surgery, a growing mass was recognised over the lacrimal sac region. On
computer tomography scan, a subdermal mass causing nasal bone destruction was
detected. Excisional biopsy of the mass was performed. Histopathologic and
immunohistochemical evaluations revealed primary diffuse large B-cell non-Hodgkin
lymphoma of the lacrimal sac. She was treated with cyclophospamide, vincristine,
adriablastine and prednisone for eight courses combined with rituximab for 6
months. During a follow-up period of 25 months, patient is stable with no
systemic disease. Although rare, lacrimal sac tumors can mimic dacryocystitis and
must be considered in differential diagnosis. In suspicious cases incisional
biopsy is recommended.
CI - Copyright (c) 2011 Elsevier Ireland Ltd. All rights reserved.
AD - Ege University Faculty of Medicine, Department of Ophthalmology, Izmir, Turkey. FAU - Palamar, Melis
AU - Palamar M
FAU - Midilli, Rasit
AU - Midilli R
FAU - Ozsan, Nazan
AU - Ozsan N
FAU - Egrilmez, Sait
AU - Egrilmez S
FAU - Sahin, Fahri
AU - Sahin F
FAU - Yagci, Ayse
AU - Yagci A
LA - eng
PT - Case Reports
PT - Journal Article
DEP - 20110224
PL - Netherlands
TA - Auris Nasus Larynx
JT - Auris, nasus, larynx
JID - 7708170
RN - 0 (Antibodies, Monoclonal, Murine-Derived)
RN - 0 (Antineoplastic Agents)
RN - 0 (rituximab)
SB - IM
MH - Antibodies, Monoclonal, Murine-Derived/administration & dosage MH - Antineoplastic Agents/administration & dosage
MH - Antineoplastic Combined Chemotherapy Protocols/administration & dosage
MH - Chronic Disease
MH - Dacryocystitis/*diagnosis
MH - Diagnosis, Differential
MH - Drug Administration Schedule
MH - Eye Neoplasms/*diagnosis/drug therapy
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - Lacrimal Apparatus Diseases/*diagnosis/drug therapy
MH - Lymphoma, Large B-Cell, Diffuse/*diagnosis/drug therapy
MH - Middle Aged
EDAT- 2011/03/01 06:00
MHDA- 2011/08/31 06:00
CRDT- 2011/03/01 06:00
PHST- 2010/09/21 [received]
PHST- 2010/12/08 [revised]
PHST- 2011/01/05 [accepted]
PHST- 2011/02/24 [aheadofprint]
AID - S0385-8146(11)00036-8 [pii]
AID - 10.1016/j.anl.2011.01.012 [doi]
PST - ppublish
SO - Auris Nasus Larynx. 2011 Oct;38(5):643-5. Epub 2011 Feb 24.
PMID- 21957956
OWN - NLM
STAT- MEDLINE
DA - 20110930
DCOM- 20120203
IS - 1744-5108 (Electronic)
IS - 0167-6830 (Linking)
VI - 30
IP - 5
DP - 2011 Oct
TI - Acute dacryocystitis associated with epstein-barr virus infection.
PG - 245-8
AB - Acute dacryocystitis is a rare complication of infectious mononucleosis with only
three previous reports in the English literature. We present two further children
with acute dacryocystitis and clinical and laboratory features of Epstein-Barr
Virus related infectious mononucleosis. Both were treated with systemic
antibiotics and one child additionally required surgical drainage of a lacrimal
sac abscess. Both children made a complete recovery without any lacrimal
symptoms. Acute dacryocystitis is uncommon in children without a history of
congenital nasolacrimal duct obstruction, and an underlying systemic condition
such as infectious mononucleosis should be suspected. In such patients,
dacryocystitis can be expected to resolve without symptoms of nasolacrimal duct
obstruction and dacryocystorhinostomy is seldom required.
AD - Victoria Eye Unit, Hereford County Hospital, Hereford, United Kingdom.
FAU - Ghauri, Abdul-Jabbar AU - Ghauri AJ
FAU - Keane, Pearse A
AU - Keane PA
FAU - Scotcher, Stephen M
AU - Scotcher SM
FAU - Clarke, Jayne L
AU - Clarke JL
FAU - Madge, Simon N
AU - Madge SN
LA - eng
PT - Case Reports
PT - Journal Article
PL - England
TA - Orbit
JT - Orbit (Amsterdam, Netherlands)
JID - 8301221
RN - 443-48-1 (Metronidazole)
RN - 73384-59-5 (Ceftriaxone)
SB - IM
MH - Acute Disease
MH - Ceftriaxone/therapeutic use
MH - Child
MH - Child, Preschool
MH - Combined Modality Therapy
MH - Dacryocystitis/drug therapy/*etiology/physiopathology MH - Drainage/methods
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - Infectious Mononucleosis/*complications/diagnosis/drug therapy
MH - Infusions, Intravenous
MH - Lacrimal Duct Obstruction/etiology/physiopathology/*therapy
MH - Male
MH - Metronidazole/therapeutic use
MH - Risk Assessment
MH - Treatment Outcome
EDAT- 2011/10/01 06:00
MHDA- 2012/02/04 06:00
CRDT- 2011/10/01 06:00
AID - 10.3109/01676830.2011.584933 [doi]
PST - ppublish
SO - Orbit. 2011 Oct;30(5):245-8.
PMID- 21613626
OWN - NLM
STAT- MEDLINE
DA - 20110928
DCOM- 20111122
IS - 1097-6817 (Electronic)
IS - 0194-5998 (Linking) VI - 145
IP - 4
DP - 2011 Oct
TI - Endocanalicular, high-pressure balloon catheter, endoscopic
dacryocystorhinostomy: a randomized controlled trial.
PG - 683-8
AB - OBJECTIVES: To conduct a prospective randomized controlled study to investigate
the safety and efficacy of endocanalicular, high-pressure, 5-mm balloon catheter,
endoscopic dacryocystorhinostomy (DCR) in adult patients with acquired complete
nasolacrimal obstruction. STUDY DESIGN: Prospective randomized controlled study.
SETTING: General hospital. SUBJECTS AND METHODS: Sixty-six adult patients with a
total of 70 procedures were recruited to undergo endoscopic DCR. They were
prospectively, equally randomized into 2 groups: endocanalicular, high-pressure,
5-mm balloon catheter, endoscopic DCR (group I) and conventional endoscopic DCR
(group II). Regular follow-up sessions were conducted to document the patient's
subjective improvement, judge ostium patency on irrigation, and record any
complications. RESULTS: Both groups demonstrated a success rate of 91.4%. There
was a shorter mean operative time (25.7 minutes) in group I (P < .001). The
number of adverse events was significantly higher in group II (P < .05). Group I
showed statistically significantly more comfort during surgery under local
anesthesia with minimal sedation (P < .05). CONCLUSION: Endocanalicular balloon
catheter endoscopic DCR shares the advantages and success rate of conventional
endoscopic DCR. In addition, the former is simpler, requires less manipulation,
consumes a shorter operative time, has a better safety profile, and can be
conducted under local anesthesia with minimal sedation. AD - Tanta University Hospitals, Tanta, Egypt. [email protected]
FAU - Ragab, Sameh M
AU - Ragab SM
FAU - el-Koddousy, Mona S
AU - el-Koddousy MS
FAU - Badr, Mohammed
AU - Badr M
LA - eng
PT - Journal Article
PT - Randomized Controlled Trial
DEP - 20110525
PL - England
TA - Otolaryngol Head Neck Surg
JT - Otolaryngology--head and neck surgery : official journal of American Academy of
Otolaryngology-Head and Neck Surgery
JID - 8508176
SB - IM
MH - Adult
MH - Balloon Dilation/*methods
MH - Dacryocystorhinostomy/*methods
MH - Endoscopes
MH - Endoscopy/instrumentation/*methods
MH - Equipment Design
MH - Female
MH - Humans MH - Lacrimal Duct Obstruction/*therapy
MH - Male
MH - Middle Aged
MH - *Nasolacrimal Duct
MH - Prospective Studies
MH - Young Adult
EDAT- 2011/05/27 06:00
MHDA- 2011/12/13 00:00
CRDT- 2011/05/27 06:00
PHST- 2011/05/25 [aheadofprint]
AID - 0194599811410534 [pii]
AID - 10.1177/0194599811410534 [doi]
PST - ppublish
SO - Otolaryngol Head Neck Surg. 2011 Oct;145(4):683-8. Epub 2011 May 25.
PMID- 21730837
OWN - NLM
STAT- MEDLINE
DA - 20110811
DCOM- 20120118
IS - 1531-7021 (Electronic)
IS - 1040-8738 (Linking)
VI - 22
IP - 5
DP - 2011 Sep TI - Laser-assisted dacryocystorhinostomy: a viable treatment option?
PG - 413-8
AB - PURPOSE OF REVIEW: Improvements in endoscopic instrumentation and evolving laser
technologies have renewed interest in laser-assisted endonasal applications, and
an increasing number of lacrimal surgeons have focused on laser-assisted
approaches to dacryocystorhinostomy (DCR). The purpose of this review was to
assess the clinical efficacy of laser-assisted DCR techniques with a particular
focus on the endocanalicular approach and to describe various laser systems and
their associated tissue effects. RECENT FINDINGS: Recent studies of
endocanalicular laser DCR suggest favorable success rates that are comparable
with external and endonasal endoscopic DCR, although there is a shortage of
robust, prospective, randomized studies. SUMMARY: Recent evidence suggests that
endocanalicular laser DCR is a well tolerated, viable treatment option for
nasolacrimal duct obstruction in selected patients with favorable results and
shorter operative times. More recent studies seem to suggest improvements in
success rates compared with older studies, although additional, well designed,
comparative studies are needed.
AD - Department of Ophthalmology, Cullen Eye Institute, Baylor College of Medicine,
Houston, Texas 77030, USA.
FAU - Lee, Seongmu
AU - Lee S
FAU - Yen, Michael T
AU - Yen MT
LA - eng
PT - Journal Article PT - Research Support, Non-U.S. Gov't
PT - Review
PL - United States
TA - Curr Opin Ophthalmol
JT - Current opinion in ophthalmology
JID - 9011108
SB - IM
MH - Dacryocystorhinostomy/*methods
MH - *Endoscopy
MH - Female
MH - Humans
MH - Lacrimal Duct Obstruction/physiopathology/*surgery
MH - Laser Therapy/*methods
MH - Male
MH - Patient Selection
MH - Randomized Controlled Trials as Topic
MH - Treatment Outcome
EDAT- 2011/07/07 06:00
MHDA- 2012/01/19 06:00
CRDT- 2011/07/07 06:00
AID - 10.1097/ICU.0b013e32834994c8 [doi]
PST - ppublish
SO - Curr Opin Ophthalmol. 2011 Sep;22(5):413-8.
PMID- 21779017 OWN - NLM
STAT- MEDLINE
DA - 20110908
DCOM- 20111109
IS - 1476-5454 (Electronic)
IS - 0950-222X (Linking)
VI - 25
IP - 9
DP - 2011 Sep
TI - A clinical trial of endoscopic vs external dacryocystorhinostomy for partial
nasolacrimal duct obstruction.
PG - 1219-24
LID - 10.1038/eye.2011.77 [doi]
AB - OBJECTIVE: A literature review revealed there is no outcome data for endoscopic
endonasal dacryocystorhinostomy (EES-DCR) in the subgroup of patients with
acquired partial nasolacrimal duct obstruction (NDO). This study aimed to compare
the results of EES-DCR vs external DCR (ext-DCR) in the treatment of partial NDO.
DESIGN: This study is designed as a prospective nonrandomised comparative
clinical trial. PARTICIPANTS: In total, 46 adult patients with acquired partial
NDO participated in this study. METHODS: Partial (sometimes called 'functional')
NDO (epiphora in the presence of patent syringing) was confirmed by nuclear
lacrimal scintigraphy or delayed drainage on dacryocystography. Patients with
'functional' epiphora from other causes were excluded. Post-operative outcome was
assessed at 6 months. Overall, 21 (46%) patients had EES-DCR and 25 patients had
(54%) ext-DCR. MAIN OUTCOME MEASURES: Subjective success was based on patient symptoms, objective success on patency with syringing and a functioning
rhinostomy evaluated using the functional endoscopic dye test (FEDT). RESULTS: In
total 18 out of 21 (86%) of EES-DCR patients had marked reduction (n=11) or
complete resolution (n=7) and 25 out of 25 (100%) of ext-DCR had marked reduction
(n=9) or complete resolution (n=16) of epiphora. In total 17 out of 18 (94%) of
the EES-DCR patients with subjective success had a positive FEDT. All 25 out of
25 (100%) ext-DCR patients with subjective success had a positive FEDT. The three
failed EES-DCR patients were all blocked on syringing. Statistically, EES-DCR
does not achieve the same success rate as ext-DCR in this study (P=0.09,
two-tailed Fisher's exact test, 0.045 one-tailed). CONCLUSIONS: Both endoscopic
and external DCRs provide satisfactory outcomes in acquired partial NDO. The
success rate is nevertheless higher in ext-DCR compared with EES-DCR.
AD - Department of Ophthalmology, Charing Cross and Hammersmith Hospitals, London, UK.
FAU - Zaidi, F H
AU - Zaidi FH
FAU - Symanski, S
AU - Symanski S
FAU - Olver, J M
AU - Olver JM
LA - eng
PT - Clinical Trial
PT - Comparative Study
PT - Journal Article
DEP - 20110722 PL - England
TA - Eye (Lond)
JT - Eye (London, England)
JID - 8703986
SB - IM
MH - Adult
MH - Aged
MH - Aged, 80 and over
MH - Dacryocystorhinostomy/*methods
MH - *Endoscopy
MH - Female
MH - Humans
MH - Lacrimal Duct Obstruction/*surgery
MH - Male
MH - Middle Aged
MH - Nasolacrimal Duct/*surgery
MH - Outcome Assessment (Health Care)
MH - Prospective Studies
PMC - PMC3178258
OID - NLM: PMC3178258 [Available on 09/01/12]
EDAT- 2011/07/23 06:00
MHDA- 2011/11/10 06:00
CRDT- 2011/07/23 06:00
PMCR- 2012/09/01 00:00
PHST- 2011/07/22 [aheadofprint] AID - eye201177 [pii]
AID - 10.1038/eye.2011.77 [doi]
PST - ppublish
SO - Eye (Lond). 2011 Sep;25(9):1219-24. doi: 10.1038/eye.2011.77. Epub 2011 Jul 22.
PMID- 21333092
OWN - NLM
STAT- MEDLINE
DA - 20110808
DCOM- 20111202
IS - 1945-8932 (Electronic)
IS - 1945-8932 (Linking)
VI - 25
IP - 4
DP - 2011 Jul-Aug
TI - What is the role of partial middle turbinectomy in endocanalicular laser-assisted
endonasal dacryocystorhinostomy?
PG - e160-5
AB - BACKGROUND: This study was designed to compare outcomes of endocanalicular
laser-assisted endonasal dacryocystorhinostomy (DCR) with and without partial
anterior middle turbinectomy. METHODS: A prospective randomized comparative study
was conducted on 91 subjects with primary acquired nasolacrimal duct obstruction,
undergoing endocanalicular (ECL) procedures. Group 1 was composed of 44 (7
bilateral) patients undergoing ECL diode laser-assisted endonasal DCR without
partial anterior middle turbinectomy and group 2 was composed of 47 (7 bilateral) patients undergoing partial anterior middle turbinectomy and ECL diode
laser-assisted endonasal DCR. Follow-up period was 11.0 (6.0-14.5 months) months
for group 1 and 9.2 (5.0-14.2 months) months for group 2. Functional success was
defined as absence of epiphora and anatomic success was defined as ability to
irrigate the lacrimal system. Anatomic and functional success at the 1st week,
3rd month, and final postoperative examinations of two groups were compared using
chi-square tests. RESULTS: Final anatomic successes were 39/51 (76%) cases for
group 1 and 51/54 (94%) cases for group 2. Final functional successes were 36/51
(%71) patients in group 1 and 48/54 (88%) patients in group 2. Group 2 had higher
success at the final examination and the difference was statistically
significant. CONCLUSION: We recommend partial anterior middle turbinectomy in all
laser ECL laser-assisted endonasal DCR, but further studies with larger sample
sizes are needed to strengthen our hypothesis.
AD - Department of Ophthalmology, Eskisehir Osmangazi University Medical Faculty,
Eskisehir, Turkey. [email protected]
FAU - Basmak, Hikmet
AU - Basmak H
FAU - Cakli, Hamdi
AU - Cakli H
FAU - Sahin, Afsun
AU - Sahin A
FAU - Gursoy, Huseyin
AU - Gursoy H
FAU - Ozer, Ahmet
AU - Ozer A FAU - Colak, Ertugrul
AU - Colak E
LA - eng
PT - Journal Article
PT - Randomized Controlled Trial
PT - Research Support, Non-U.S. Gov't
DEP - 20110211
PL - United States
TA - Am J Rhinol Allergy
JT - American journal of rhinology & allergy
JID - 101490775
SB - IM
MH - Adult
MH - Aged
MH - *Dacryocystorhinostomy
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - Lacrimal Apparatus/*metabolism/pathology/surgery
MH - Lacrimal Apparatus Diseases/diagnosis/pathology/physiopathology/*surgery
MH - Lasers/utilization
MH - Male
MH - Middle Aged
MH - Nasolacrimal Duct/pathology/*surgery
MH - Prospective Studies MH - Recovery of Function
MH - Turbinates/pathology/*surgery
EDAT- 2011/02/22 06:00
MHDA- 2011/12/13 00:00
CRDT- 2011/02/22 06:00
PHST- 2011/02/11 [aheadofprint]
AID - 3598 [pii]
AID - 10.2500/ajra.2011.25.3598 [doi]
PST - ppublish
SO - Am J Rhinol Allergy. 2011 Jul-Aug;25(4):e160-5. Epub 2011 Feb 11.
PMID- 21394118
OWN - NLM
STAT- MEDLINE
DA - 20110609
DCOM- 20110908
LR - 20120619
IS - 1476-5454 (Electronic)
IS - 0950-222X (Linking)
VI - 25
IP - 6
DP - 2011 Jun
TI - Effects of Merogel coverage on wound healing and ostial patency in endonasal
endoscopic dacryocystorhinostomy for primary chronic dacryocystitis.
PG - 746-53 LID - 10.1038/eye.2011.44 [doi]
AB - PURPOSE: To investigate the effects of Merogel coverage on ostial patency in
endonasal endoscopic dacryocystorhinostomy (EES-DCR) for primary chronic
dacryocystitis (PCD). METHODS: In all, 260 patients with unilateral PCD were
randomized into two groups: the Merogel group and the control group. All patients
underwent EES-DCR. The Merogel group received Merogel covering the wound 1-2 mm
around the ostium and the control group received no treatment. Patients were
followed up for 9 months. The mucosal epithelialization of the wound, the
proliferation of fibrosis tissue, and the success rate of ostial patency were
compared. RESULTS: Our study included 112 patients in the Merogel group and 115
patients in the control group. At the 2-week review, intact mucosal epithelium
lined the ostia in 96 Merogel patients compared with 80 control patients (ITT
analysis: chi(2)=4.502, P=0.034). At the 9-month review, scars were present in 18
patients in the Merogel group compared with 39 patients in the control group (ITT
analysis: chi(2)=9.909, P=0.002, ITT analysis). No differences were observed in
the granulation formation between the two groups. The success rate of ostial
patency reached 94.6% (106/112) in the Merogel group compared with 80% (92/115)
in the control group (ITT analysis: chi(2)=4.151, P=0.042). CONCLUSION: Merogel
coverage may enhance the success rate of EES-DCR for PCD by promoting mucosal
epithelial healing and preventing excessive scarring.
AD - Department of Orbital and Oculoplasty Surgery, Eye Hospital of Wenzhou Medical
College, Wenzhou, Zhejiang, PR China. [email protected]
FAU - Wu, W
AU - Wu W
FAU - Cannon, P S AU - Cannon PS
FAU - Yan, W
AU - Yan W
FAU - Tu, Y
AU - Tu Y
FAU - Selva, D
AU - Selva D
FAU - Qu, J
AU - Qu J
LA - eng
PT - Journal Article
PT - Randomized Controlled Trial
DEP - 20110311
PL - England
TA - Eye (Lond)
JT - Eye (London, England)
JID - 8703986
RN - 443-48-1 (Metronidazole)
RN - 9004-61-9 (Hyaluronic Acid)
SB - IM
MH - Adult
MH - Chronic Disease
MH - Dacryocystitis/*drug therapy/surgery
MH - Dacryocystorhinostomy/*methods
MH - *Endoscopy MH - Epithelium/pathology
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - Hyaluronic Acid/*therapeutic use
MH - Male
MH - Metronidazole/pharmacokinetics/*pharmacology
MH - Middle Aged
MH - Nasal Mucosa/pathology
MH - Wound Healing/*drug effects
PMC - PMC3178118
OID - NLM: PMC3178118
EDAT- 2011/03/12 06:00
MHDA- 2011/09/09 06:00
CRDT- 2011/03/12 06:00
PHST- 2011/03/11 [aheadofprint]
AID - eye201144 [pii]
AID - 10.1038/eye.2011.44 [doi]
PST - ppublish
SO - Eye (Lond). 2011 Jun;25(6):746-53. doi: 10.1038/eye.2011.44. Epub 2011 Mar 11.
PMID- 21356145
OWN - NLM
STAT- MEDLINE
DA - 20111206 DCOM- 20120327
IS - 1748-5460 (Electronic)
IS - 0022-2151 (Linking)
VI - 125
IP - 6
DP - 2011 Jun
TI - Efficacy of endonasal dacryocystorhinostomy, using 'cold steel' instruments
without stenting, in treatment of distal nasolacrimal duct obstruction.
PG - 590-4
AB - OBJECTIVE: To assess the efficacy of an endonasal dacryocystorhinostomy technique
using conventional instruments, without the use of any adjunctive techniques.
STUDY DESIGN: Prospective, non-randomised, cohort study. METHODS: Patients
diagnosed with nasolacrimal duct obstruction between January 2006 and December
2008 were included in the study. Seventy-eight endonasal dacryocystorhinostomies
(primary or revision) were performed with conventional 'cold steel' instruments.
The technique involved complete exposure and marsupialisation of the lacrimal
sac. No adjunctive procedures were used. Success was defined as complete
resolution of epiphora and a patent lacrimal system, evaluated by lacrimal
irrigation and endoscopy, one year post-operatively. RESULTS: Seventy-four of the
78 cases were symptom-free after a minimum follow up of 12 months, giving an
overall success rate of 94.9 per cent. The success rates for primary and revision
cases were 95.5 and 90.9 per cent, respectively. CONCLUSION: Meticulous surgical
technique can ensure high success rates with the use of conventional cold steel
instruments, without the use of adjunctive procedures, making endonasal
dacryocystorhinostomy a cost-effective, reliable procedure. AD - Department of Otorhinolaryngology, Sri Siddhartha Medical College Hospital and
Research Center, Siddhartha University, Tumkur, Karnataka, India.
FAU - Ananth, L
AU - Ananth L
FAU - Hosamani, P
AU - Hosamani P
FAU - Chary, G
AU - Chary G
LA - eng
PT - Journal Article
DEP - 20110228
PL - England
TA - J Laryngol Otol
JT - The Journal of laryngology and otology
JID - 8706896
RN - 12597-69-2 (Steel)
SB - AIM
SB - IM
MH - Adolescent
MH - Adult
MH - Aged
MH - Child
MH - Child, Preschool
MH - Cost-Benefit Analysis
MH - Dacryocystorhinostomy/economics/instrumentation/*methods/statistics & numerical data
MH - Female
MH - Humans
MH - Lacrimal Apparatus Diseases/surgery
MH - Lacrimal Duct Obstruction/*surgery
MH - Male
MH - Middle Aged
MH - Nasal Mucosa/surgery
MH - Nasolacrimal Duct/*surgery
MH - *Natural Orifice Endoscopic Surgery
MH - Prospective Studies
MH - Reoperation
MH - Steel
MH - Surgical Flaps
MH - Treatment Outcome
MH - Young Adult
EDAT- 2011/03/02 06:00
MHDA- 2012/03/28 06:00
CRDT- 2011/03/02 06:00
PHST- 2011/02/28 [aheadofprint]
AID - S002221511100017X [pii]
AID - 10.1017/S002221511100017X [doi]
PST - ppublish
SO - J Laryngol Otol. 2011 Jun;125(6):590-4. Epub 2011 Feb 28.
PMID- 21255867
OWN - NLM
STAT- MEDLINE
DA - 20110328
DCOM- 20110719
LR - 20111117
IS - 1773-0597 (Electronic)
IS - 0181-5512 (Linking)
VI - 34
IP - 3
DP - 2011 Mar
TI - [Fusobacterium nucleatum isolated from a patient presenting lachrymal
canaliculitis].
PG - 188.e1-4
AB - A 68-year-old woman presented with a painless inflammation of the right superior
eyelid that had started several weeks before. The clinical diagnosis concluded in
canaliculitis and the solid concretions were surgically extracted from the
superior canalicula. The anaerobic bacteria Fusobacterium nucleatum sp. nucleatum
was isolated. Signs dramatically regressed two weeks after surgery followed by
one course of oral amoxicillin and clavulanic acid associated with topical
tobramycin. The clinical signs had disappeared two months later.
CI - Copyright (c) 2010 Elsevier Masson SAS. All rights reserved.
AD - Laboratoire de biologie, centre hospitalier national d'ophtalmologie des
Quinze-Vingt, 28, rue de Charenton, 75012 Paris, France.
FAU - Borsali, E AU - Borsali E
FAU - Goldschmidt, P
AU - Goldschmidt P
FAU - Mann, F
AU - Mann F
FAU - Sterkers, M
AU - Sterkers M
FAU - Le Bouter, A
AU - Le Bouter A
FAU - Ailem, N
AU - Ailem N
FAU - Legrand, P
AU - Legrand P
FAU - Gaujoux, T
AU - Gaujoux T
FAU - Batellier, L
AU - Batellier L
FAU - Sullam-Rea, M-L
AU - Sullam-Rea ML
FAU - Bouaziz, T
AU - Bouaziz T
FAU - Sahel, J A
AU - Sahel JA
FAU - Chaumeil, C
AU - Chaumeil C LA - fre
PT - Case Reports
PT - English Abstract
PT - Journal Article
TT - Fusobacterium nucleatum isole chez un patient presentant une canaliculite.
DEP - 20110120
PL - France
TA - J Fr Ophtalmol
JT - Journal francais d'ophtalmologie
JID - 7804128
RN - 0 (Anti-Bacterial Agents)
RN - 32986-56-4 (Tobramycin)
RN - 74469-00-4 (Amoxicillin-Potassium Clavulanate Combination)
RN - Canaliculitis
SB - IM
MH - Aged
MH - Amoxicillin-Potassium Clavulanate Combination/administration & dosage/therapeutic
use
MH - Anti-Bacterial Agents/administration & dosage/therapeutic use
MH - Combined Modality Therapy
MH - Corneal Ulcer/microbiology
MH - Dacryocystitis
MH - Dacryocystorhinostomy
MH - Drug Therapy, Combination
MH - Emergencies MH - Female
MH - Fusobacterium Infections/complications/drug therapy/*microbiology/surgery
MH - Fusobacterium nucleatum/*isolation & purification
MH - Humans
MH - Lacrimal Apparatus Diseases/complications/drug therapy/*microbiology/surgery
MH - Lacrimal Duct Obstruction/etiology/surgery
MH - Tobramycin/administration & dosage/therapeutic use
EDAT- 2011/01/25 06:00
MHDA- 2011/07/20 06:00
CRDT- 2011/01/25 06:00
PHST- 2010/07/06 [received]
PHST- 2010/10/12 [accepted]
PHST- 2011/01/20 [aheadofprint]
AID - S0181-5512(10)00327-X [pii]
AID - 10.1016/j.jfo.2010.10.012 [doi]
PST - ppublish
SO - J Fr Ophtalmol. 2011 Mar;34(3):188.e1-4. Epub 2011 Jan 20.
PMID- 21224749
OWN - NLM
STAT- MEDLINE
DA - 20110307
DCOM- 20110525
IS - 1537-2677 (Electronic)
IS - 0740-9303 (Linking) VI - 27
IP - 2
DP - 2011 Mar-Apr
TI - Results of lacrimal gland botulinum toxin injection for epiphora in lacrimal
obstruction and gustatory tearing.
PG - 119-21
AB - PURPOSE: To describe the author's experience with the use of botulinum toxin
(Botox, Allergan Inc., Irvine, CA, U.S.A.) injection in the palpebral lobe of the
lacrimal gland for symptomatic epiphora due to lacrimal obstruction or gustatory
tearing. METHODS: This is a retrospective review of 46 patients treated by the
author with botulinum toxin injection in the palpebral lobe of the lacrimal gland
for symptomatic epiphora due to lacrimal obstruction or gustatory tearing from
2001 through 2008. All patients were injected with 2.5 units of botulinum toxin,
and the patients' subjective responses were assessed 1 to 2 weeks later. If there
was insufficient response, they were reinjected with an additional 2.5 units of
botulinum toxin and re-evaluated in 1 to 2 weeks. The response to the treatment
and complications were evaluated. RESULTS: Overall, 74% of patients treated felt
that tearing was mostly or completely improved. The only complication was
temporary ptosis in 11% of the patients. CONCLUSION: Botulinum toxin injection in
the palpebral lobe of the lacrimal gland can be used effectively and safely for
symptomatic epiphora due to lacrimal obstruction and gustatory tearing. Although
the beneficial results are temporary, the patient satisfaction in selected
patients is high.
AD - The Emory Clinic, Atlanta, Georgia 30322, USA. [email protected]
FAU - Wojno, Ted H AU - Wojno TH
LA - eng
PT - Journal Article
PT - Research Support, Non-U.S. Gov't
PL - United States
TA - Ophthal Plast Reconstr Surg
JT - Ophthalmic plastic and reconstructive surgery
JID - 8508431
RN - 0 (Neuromuscular Agents)
RN - 0 (onabotulinumtoxinA)
RN - EC 3.4.24.69 (Botulinum Toxins, Type A)
SB - IM
MH - Adult
MH - Aged
MH - Aged, 80 and over
MH - Botulinum Toxins, Type A/*administration & dosage
MH - Female
MH - Humans
MH - Injections, Intraocular
MH - Lacrimal Apparatus/*drug effects/secretion
MH - Lacrimal Apparatus Diseases/*drug therapy/etiology/metabolism
MH - Lacrimal Duct Obstruction/complications/drug therapy/metabolism
MH - Male
MH - Middle Aged
MH - Neuromuscular Agents/*administration & dosage MH - Patient Satisfaction
MH - Retrospective Studies
MH - Tears/secretion
MH - Treatment Outcome
EDAT- 2011/01/13 06:00
MHDA- 2011/05/26 06:00
CRDT- 2011/01/13 06:00
AID - 10.1097/IOP.0b013e318201d1d3 [doi]
PST - ppublish
SO - Ophthal Plast Reconstr Surg. 2011 Mar-Apr;27(2):119-21.
PMID- 21271601
OWN - NLM
STAT- MEDLINE
DA - 20110128
DCOM- 20110308
IS - 1531-4995 (Electronic)
IS - 0023-852X (Linking)
VI - 121
IP - 2
DP - 2011 Feb
TI - Efficacy of mitomycin C in endonasal endoscopic dacryocystorhinostomy.
PG - 433-6
LID - 10.1002/lary.21292 [doi]
AB - OBJECTIVES/HYPOTHESIS: To evaluate the efficacy of intraoperative mitomycin C (MMC) in endonasal endoscopic dacryocystorhinostomy. STUDY DESIGN: Randomized
controlled trial. METHODS: Fifty patients with primary acquired nasolacrimal duct
obstruction were enrolled and randomly allocated into the treatment and control
group. The patients underwent standard endonasal endoscopic dacryocystorhinostomy
with mucosal flaps and mitomycin C or placebo on each group. The ostium size was
measured at 3 months, 6 months, and 12 months to evaluate the effect of mitomycin
C and placebo, and the patency of the lacrimal drainage system was assessed.
RESULTS: There was no statistical significance in the success rate between the
MMC group and the control group at 1-year follow-up (84.6% vs.79.2%,
respectively, P = .59). At the 6-month and 12-month visits, the mean ostium size
in the MMC group was 10.8 mm(2) (SD = 3.17) and 3.0 mm(2) (SD = 1.78),
respectively, which were prominently larger than the control group at 7.1 mm(2)
(SD = 2.62; P < .001, 95% CI, 0.84-5.45) and 1.6 mm(2) (SD = 1.18; P = .004, 95%
CI, 0.49-2.38). CONCLUSIONS: There was no statistically significant difference in
the success rates of both groups, but MMC seems to have a conspicuous effect on
the healing process at the ostium.
CI - Copyright (c) 2011 The American Laryngological, Rhinological, and Otological
Society, Inc.
AD - Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University and
King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
FAU - Tirakunwichcha, Suppapong
AU - Tirakunwichcha S
FAU - Aeumjaturapat, Songklot
AU - Aeumjaturapat S FAU - Sinprajakphon, Siripong
AU - Sinprajakphon S
LA - eng
PT - Journal Article
PT - Randomized Controlled Trial
DEP - 20110104
PL - United States
TA - Laryngoscope
JT - The Laryngoscope
JID - 8607378
RN - 50-07-7 (Mitomycin)
SB - IM
MH - Adult
MH - Dacryocystorhinostomy/*methods
MH - *Endoscopy
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - Intraoperative Period
MH - Lacrimal Duct Obstruction/surgery
MH - Male
MH - Mitomycin/*therapeutic use
MH - Nasolacrimal Duct/*surgery
EDAT- 2011/01/29 06:00
MHDA- 2011/03/09 06:00 CRDT- 2011/01/29 06:00
PHST- 2010/07/23 [accepted]
PHST- 2011/01/04 [aheadofprint]
AID - 10.1002/lary.21292 [doi]
PST - ppublish
SO - Laryngoscope. 2011 Feb;121(2):433-6. doi: 10.1002/lary.21292. Epub 2011 Jan 4.
PMID- 21249688
OWN - NLM
STAT- MEDLINE
DA - 20110120
DCOM- 20110228
LR - 20110309
IS - 1469-493X (Electronic)
IS - 1361-6137 (Linking)
IP - 1
DP - 2011
TI - Endonasal versus external dacryocystorhinostomy for nasolacrimal duct
obstruction.
PG - CD007097
AB - BACKGROUND: Dacryocystorhinostomy (DCR) procedures can be performed using
external or endonasal approaches. The comparative success rates of these
procedures are unknown. OBJECTIVES: To compare the success rates of external and
endonasal approaches to DCR. SEARCH STRATEGY: We searched CENTRAL (which contains
the Cochrane Eyes and Vision Group Trials Register) (The Cochrane Library 2010, Issue 11), MEDLINE (January 1950 to December 2010), EMBASE (January 1980 to
December 2010), Latin American and Caribbean Literature on Health Sciences
(LILACS) (January 1982 to December 2010), the metaRegister of Controlled Trials
(mRCT) (www.controlled-trials.com) (December 2010), ClinicalTrials.gov
(www.clinicaltrials.gov) (December 2010) and Web of Science Conference
Proceedings Citation Index- Science (CPCI-S) (January 1990 to December 2010).
There were no language or date restrictions in the search for trials. The
electronic databases were last searched on 7 December 2010. We requested or
examined relevant conference proceedings for appropriate trials. SELECTION
CRITERIA: We included all randomised controlled trials (RCTs) comparing external
and endonasal dacryocystorhinostomies. DATA COLLECTION AND ANALYSIS: Two review
authors independently performed data extraction and assessment of quality with a
predefined form. We contacted investigators to clarify the methodological quality
of the studies. MAIN RESULTS: We identified one trial that fulfilled the
inclusion criteria. This trial compared 64 DCR procedures (32 external and 32
endonasal procedures). Endonasal DCR was four times more likely to fail compared
to external DCR. This was statistically significant (95% confidence interval (CI)
1.25 to 12.84). AUTHORS' CONCLUSIONS: The only trial included in the review
provides evidence that endonasal DCR has statistically higher risk of failure
compared to external DCR. However, this conclusion is limited by paucity of RCTs,
small number of participants and lack of clarity of the methodological process.
Well conducted RCTs with sufficient power are required to answer the research
question.
AD - St Paul's Eye Unit, Royal Liverpool and Broadgreen University Hospital,
Liverpool, UK, L7 8XP. FAU - Anijeet, Deepa
AU - Anijeet D
FAU - Dolan, Lynne
AU - Dolan L
FAU - Macewen, Caroline J
AU - Macewen CJ
LA - eng
PT - Journal Article
PT - Review
DEP - 20110119
PL - England
TA - Cochrane Database Syst Rev
JT - Cochrane database of systematic reviews (Online)
JID - 100909747
SB - IM
MH - Dacryocystorhinostomy/*methods
MH - Humans
MH - Lacrimal Duct Obstruction/*surgery
MH - Randomized Controlled Trials as Topic
MH - Treatment Failure
EDAT- 2011/01/21 06:00
MHDA- 2011/03/01 06:00
CRDT- 2011/01/21 06:00
AID - 10.1002/14651858.CD007097.pub2 [doi]
PST - epublish SO - Cochrane Database Syst Rev. 2011 Jan 19;(1):CD007097.
PMID- 21207444
OWN - NLM
STAT- Publisher
DA - 20110105
IS - 1531-4995 (Electronic)
IS - 0023-852X (Linking)
DP - 2011 Jan 4
TI - Efficacy of mitomycin C in endonasal endoscopic dacryocystorhinostomy.
AB - OBJECTIVES/HYPOTHESIS:: To evaluate the efficacy of intraoperative mitomycin C
(MMC) in endonasal endoscopic dacryocystorhinostomy. STUDY DESIGN:: Randomized
controlled trial. METHODS:: Fifty patients with primary acquired nasolacrimal
duct obstruction were enrolled and randomly allocated into the treatment and
control group. The patients underwent standard endonasal endoscopic
dacryocystorhinostomy with mucosal flaps and mitomycin C or placebo on each
group. The ostium size was measured at 3 months, 6 months, and 12 months to
evaluate the effect of mitomycin C and placebo, and the patency of the lacrimal
drainage system was assessed. RESULTS:: There was no statistical significance in
the success rate between the MMC group and the control group at 1-year follow-up
(84.6% vs.79.2%, respectively, P = .59). At the 6-month and 12-month visits, the
mean ostium size in the MMC group was 10.8 mm(2) (SD = 3.17) and 3.0 mm(2) (SD =
1.78), respectively, which were prominently larger than the control group at 7.1
mm(2) (SD = 2.62; P < .001, 95% CI, 0.84-5.45) and 1.6 mm(2) (SD = 1.18; P =
.004, 95% CI, 0.49-2.38). CONCLUSIONS:: There was no statistically significant difference in the success rates of both groups, but MMC seems to have a
conspicuous effect on the healing process at the ostium.
AD - Departments of Ophthalmology , Faculty of Medicine, Chulalongkorn University and
King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
AU - Tirakunwichcha S
AU - Aeumjaturapat S
AU - Sinprajakphon S
LA - ENG
PT - JOURNAL ARTICLE
DEP - 20110104
TA - Laryngoscope
JT - The Laryngoscope
JID - 8607378
EDAT- 2011/01/06 06:00
MHDA- 2011/01/06 06:00
CRDT- 2011/01/06 06:00
AID - 10.1002/lary.21292 [doi]
PST - aheadofprint
SO - Laryngoscope. 2011 Jan 4.
PMID- 22553710
OWN - NLM
STAT- In-Data-Review
DA - 20120503
IS - 2227-4898 (Electronic) IS - 2222-3959 (Linking)
VI - 4
IP - 5
DP - 2011
TI - Aerocyst urethral catheter insertion compared to expansion sponges application in
external dacryocystorhinostomy.
PG - 498-501
AB - AIM: To evaluate the clinical effect and complications of two different filling
materials (aerocyst urethral catheter and expansion sponges) applying in external
dacryocystorhinostomy (EXT-DCR) and compare their advantages and disadvantages.
METHODS: A retrospective study was made in the period from April, 1 2000 to
April, 1 2005. Totally 180 patients (240 eyes) underwent the EX-DCR using
different filling materials and divided into three groups randomly: negative
control groups (group 1), expansion sponges group (group 2) and aerocyst urethral
catheter group (group 3). The gender, etiology, clinical findings, surgical
technique, filling materials, the condition of ocular surface and complications
were analyzed. Filling materials were removed during day 7. Postoperative success
was determined by lacrimal patency to irrigation, a positive dye test, hemorrhage
and errhysis conditions after extubation and subjective resolution of epiphora
and liquor puris. RESULTS: During a mean follow-up of 5.14+/-1.69 years, the
success rate were 73.7% (group 1), 86.5% (group 2), 98.7% (group 3) in three
groups. There was significant statistical difference among three groups in the
surgical success rate and the operative complications (including hemorrhage,
errhysis, periorbital ecchymosis after extubation)(P<0.05). CONCLUSION: EXT-DCR
with aerocyst urethral cathete intraoperatively have higher success rate, fewer operative complications and a high patient satisfaction ,and can be used to
simplify and speed up traditional EXT-DCR.
AD - Department of Ophthalmology, the First Affiliated Hospital of Nanchang
University, Nanchang 330006, Jiangxi Province, China.
FAU - Shao, Yi
AU - Shao Y
FAU - Yu, Yao
AU - Yu Y
FAU - Pei, Chong-Gang
AU - Pei CG
FAU - Zhou, Qiong
AU - Zhou Q
FAU - Dong, Wen-Jia
AU - Dong WJ
FAU - Qu, Yangluowa
AU - Qu Y
FAU - Yang, Lu
AU - Yang L
FAU - Gao, Gui-Ping
AU - Gao GP
LA - eng
PT - Journal Article
DEP - 20111018
PL - China
TA - Int J Ophthalmol JT - International journal of ophthalmology
JID - 101553860
PMC - PMC3340728
OID - NLM: PMC3340728
EDAT- 2011/01/01 00:00
MHDA- 2011/01/01 00:00
CRDT- 2012/05/04 06:00
PHST- 2011/07/27 [received]
PHST- 2011/09/23 [accepted]
PHST- 2011/10/18 [epublish]
AID - 10.3980/j.issn.2222-3959.2011.05.08 [doi]
AID - ijo-04-05-498 [pii]
PST - ppublish
SO - Int J Ophthalmol. 2011;4(5):498-501. Epub 2011 Oct 18.
PMID- 21276064
OWN - NLM
STAT- MEDLINE
DA - 20110131
DCOM- 20110602
LR - 20111117
IS - 1525-1470 (Electronic)
IS - 0736-8046 (Linking)
VI - 28
IP - 1 DP - 2011 Jan-Feb
TI - Case report: Congenital dacryocystocele and dacryocystitis.
PG - 70-2
LID - 10.1111/j.1525-1470.2010.01365.x [doi]
AB - Congenital dacryocystocele is a uncommon type of nasolacrimal duct obstruction.
Differential diagnosis for masses in the medial canthal region of a newborn
include encephalocele, hemangioma, nasal glioma, and dermoid cyst. Because of the
risk of becoming infected (acute dacryocystitis) and potentially lethal due to
septicemia, aggressive management, including admission for intravenous
antibiotics and surgical removal, is now advocated by many pediatric
ophthalmologists if the cyst cannot be decompressed. Because of the commonly
associated nasal cyst, infants with nasolacrimal dacryocyctocele may also
experience respiratory distress especially when breast-feeding. The following
case of dacryocystocele, which had progressed to dacryocystitis, was misdiagnosed
as an infantile hemangioma. It is important to diagnose this entity quickly and
refer for appropriate antibiotic and surgical management to avoid more serious
sequelae of sepsis and possible death.
CI - (c) 2011 Wiley Periodicals, Inc.
AD - Department of Pediatrics, Geisinger Medical Center, Danville, PA 17821, USA.
FAU - Fussell, J Nicole F
AU - Fussell JN
FAU - Wilson, Thomas
AU - Wilson T
FAU - Pride, Howard AU - Pride H
LA - eng
PT - Case Reports
PT - Journal Article
DEP - 20110125
PL - United States
TA - Pediatr Dermatol
JT - Pediatric dermatology
JID - 8406799
RN - 0 (Anti-Bacterial Agents)
RN - Hemangioma, capillary infantile
SB - IM
MH - Anti-Bacterial Agents/therapeutic use
MH - Dacryocystitis/*congenital/*diagnosis/drug therapy/surgery
MH - Diagnosis, Differential
MH - Female
MH - Hemangioma, Capillary/congenital/diagnosis
MH - Humans
MH - Infant, Newborn
MH - Lacrimal Apparatus Diseases/*congenital/*diagnosis/drug therapy/urine
MH - Lacrimal Duct Obstruction/congenital/diagnosis/surgery
MH - Neoplastic Syndromes, Hereditary
MH - Treatment Outcome
EDAT- 2011/02/01 06:00
MHDA- 2011/06/03 06:00 CRDT- 2011/02/01 06:00
PHST- 2011/01/25 [aheadofprint]
AID - 10.1111/j.1525-1470.2010.01365.x [doi]
PST - ppublish
SO - Pediatr Dermatol. 2011 Jan-Feb;28(1):70-2. doi: 10.1111/j.1525-1470.2010.01365.x.
Epub 2011 Jan 25.
PMID- 21194883
OWN - NLM
STAT- MEDLINE
DA - 20110118
DCOM- 20110224
IS - 0755-4982 (Print)
IS - 0755-4982 (Linking)
VI - 40
IP - 1 Pt 2
DP - 2011 Jan
TI - Pulmonary manifestations of Sjogren's syndrome.
PG - e49-64
AB - Sjogren's syndrome is a chronic inflammatory disorder characterized by
lymphocytic infiltration of exocrine glands, mainly the lacrimal and salivary
glands. However, extraglandular organ systems may frequently be involved,
including the lungs. Although subclinical pulmonary inflammation exists in more
than 50% of patients, clinically significant pulmonary involvement affects
approximately 10% of patients and may be the first manifestation of the disease. The entire respiratory tract may be involved, with a wide spectrum of
manifestations including xerotrachea and bronchial sicca, obstructive small
airway disease, various patterns of interstitial lung disease, lymphoinfiltrative
or lymphoproliferative lung disease, such as lymphoma (usually of MALT type),
pulmonary hypertension, pleural involvement, lung cysts, and pulmonary
amyloidosis.
CI - Copyright A(c) 2010 Elsevier Masson SAS. All rights reserved.
AD - Service de medecine interne, Centre national de reference des maladies
systemiques et auto-immunes rares (sclerodermie), universite Lille2, CHRU de
Lille, place de Verdun, 59037 Lille, France. [email protected]
FAU - Hatron, Pierre-Yves
AU - Hatron PY
FAU - Tillie-Leblond, Isabelle
AU - Tillie-Leblond I
FAU - Launay, David
AU - Launay D
FAU - Hachulla, Eric
AU - Hachulla E
FAU - Fauchais, Anne Laure
AU - Fauchais AL
FAU - Wallaert, Benoit
AU - Wallaert B
LA - eng
PT - Journal Article
PT - Review DEP - 20101230
PL - France
TA - Presse Med
JT - Presse medicale (Paris, France : 1983)
JID - 8302490
SB - IM
MH - Humans
MH - Lung Diseases/diagnosis/drug therapy/*etiology
MH - Lung Diseases, Interstitial/etiology
MH - Pleural Diseases/etiology
MH - Sjogren's Syndrome/*complications
EDAT- 2011/01/05 06:00
MHDA- 2011/02/25 06:00
CRDT- 2011/01/04 06:00
PHST- 2010/09/22 [received]
PHST- 2010/11/12 [revised]
PHST- 2010/11/15 [accepted]
PHST- 2010/12/30 [aheadofprint]
AID - S0755-4982(10)00645-7 [pii]
AID - 10.1016/j.lpm.2010.11.002 [doi]
PST - ppublish
SO - Presse Med. 2011 Jan;40(1 Pt 2):e49-64. Epub 2010 Dec 30.
PMID- 21442083
OWN - NLM STAT- MEDLINE
DA - 20110407
DCOM- 20110726
IS - 0300-0729 (Print)
IS - 0300-0729 (Linking)
VI - 48
IP - 4
DP - 2010 Dec
TI - Symptom score questionnaire for nasolacrimal duct obstruction in adults--a novel
tool to assess the outcome after endoscopic dacryocystorhinostomy.
PG - 446-51
AB - BACKGROUND: The incidence of nasolacrimal pathway obstruction increases with age,
and dacryocystorhinostomy (DCR) is a commonly applied surgical technique to treat
severe cases. However, no disease-specific tools to assess the symptoms and the
subjective outcome after DCR have been established. We have developed a specific
Nasolacrimal Duct Obstruction Symptom Score (NLDO-SS) questionnaire to evaluate
the outcome, and tested it in a prospective clinical trial. STUDY DESIGN:
Prospective clinical follow-up study. METHODS: Sixty-eight consecutive primary
endoscopic dacryocystorhinostomy (EN-DCR) procedures were performed in 64
patients during 2004-2008. Preoperatively and during the three follow-up visits
(at 1 week, 2 and 6 months), the patients filled in the NLDO-SS, and at the
second and third follow-up visits they also filled in the Glasgow Benefit
Inventory (GBI) questionnaire. At one year after the operation, a GBI
questionnaire was sent to the patients. RESULTS: The surgical success rate of
EN-DCR was 93 %. EN-DCR resulted in a significant reduction in all of the eight symptoms scores of the NLDO-SS (p= 0.001). The GBI scores indicated a significant
benefit at 2 months (+37 (SD; 28) and an even higher benefit at 6 months after
surgery (+52 (SD; 29), p= 0.001), but no further improvement was found between 6
and 12 months (+52 vs +52, p= 1.0). The correlation between the total GBI and
NLDO-SS was significant (p=0.001). CONCLUSIONS: EN-DCR significantly improves the
quality of life as measured by the GBI. The NLDO-SS correlated with the GBI and
gave more information about the benefits after EN-DCR than GBI alone. The NLDO-SS
proved to be an effective tool to evaluate lacrimal obstructions and EN-DCR
benefits. Further studies to validate NLDO-SS are needed.
AD - Department of Otorhinolaryngology, Institute of Clinical Medicine, Kuopio
University Hospital, and University of Eastern Finland, Finland.
FAU - Smirnov, Grigori
AU - Smirnov G
FAU - Tuomilehto, Henri
AU - Tuomilehto H
FAU - Kokki, Hannu
AU - Kokki H
FAU - Kemppainen, Tatu
AU - Kemppainen T
FAU - Kiviniemi, Vesa
AU - Kiviniemi V
FAU - Nuutinen, Juhani
AU - Nuutinen J
FAU - Kaarniranta, Kai
AU - Kaarniranta K FAU - Seppa, Juha
AU - Seppa J
LA - eng
PT - Clinical Trial
PT - Journal Article
PL - Netherlands
TA - Rhinology
JT - Rhinology
JID - 0347242
SB - IM
MH - Age Factors
MH - Aged
MH - *Dacryocystorhinostomy
MH - Endoscopy
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - *Lacrimal Duct Obstruction/diagnosis/pathology/physiopathology/surgery
MH - Male
MH - Middle Aged
MH - Monitoring, Physiologic/*standards
MH - Nasolacrimal Duct/pathology/physiopathology/surgery
MH - Patient Satisfaction/*statistics & numerical data
MH - Perioperative Period/*standards
MH - Prospective Studies MH - Quality Assurance, Health Care/methods
MH - *Questionnaires
MH - Severity of Illness Index
MH - Sickness Impact Profile
MH - Treatment Outcome
EDAT- 2011/03/29 06:00
MHDA- 2011/07/27 06:00
CRDT- 2011/03/29 06:00
AID - 10.4193/Rhin [doi]
PST - ppublish
SO - Rhinology. 2010 Dec;48(4):446-51.
PMID- 21119404
OWN - NLM
STAT- MEDLINE
DA - 20101201
DCOM- 20110602
IS - 1536-3732 (Electronic)
IS - 1049-2275 (Linking)
VI - 21
IP - 6
DP - 2010 Nov
TI - Surgical outcomes of primary and revision endoscopic dacryocystorhinostomy.
PG - 1706-8
AB - OBJECTIVE: In the current study, whereas the results of endoscopic primary and revision endoscopic dacryocystorhinostomies (END-DCR) were evaluated, the success
rates in patients who did or did not undergo nasal surgery were also compared.
METHODS: A retrospective medical record review of 70 patients (with a total of 72
affected cases) who were admitted to our clinic with a primary complaint of
epiphora between January 2002 and July 2009 was performed. Patients who required
additional nasal procedures were also included in the analysis. A successful DCR
was defined as relief of symptoms on testing with irrigation at the last
follow-up visit. RESULTS: The success rates were 82.1% (23/28 DCRs) in the
primary END-DCR group and 84.1% (37/44 DCRs) in the revision END-DCR group. There
were no significant differences between the groups regarding overall surgical
success rates (P = 0.829). The need for additional nasal surgery was
significantly higher in the revision cases (52.3%) than the primary cases (28.6%;
P = 0.048). No significant difference regarding success rates existed between the
patients who required an additional septoplasty or ancillary sinus surgery and
the patients who did not have nasal pathology and underwent END-DCR alone (P =
0.456). The mean follow-up period was 11 months in the revision END-DCR group and
8 months in the primary END-DCR group. CONCLUSIONS: Endoscopic DCR should be
considered as the treatment of choice in cases with intranasal pathologies.
Endoscopic DCR is a safe and effective procedure in revision cases, as well as in
primary cases.
AD - Department of Otorhinolaryngology, Vakif Gureba Training and Research Hospital,
Istanbul, Turkey. [email protected]
FAU - Korkut, Arzu Yasemin
AU - Korkut AY
FAU - Teker, Aysenur Meric AU - Teker AM
FAU - Yazici, Mine Zahide
AU - Yazici MZ
FAU - Kahya, Volkan
AU - Kahya V
FAU - Gedikli, Orhan
AU - Gedikli O
FAU - Kayhan, Fatma Tulin
AU - Kayhan FT
LA - eng
PT - Comparative Study
PT - Journal Article
PL - United States
TA - J Craniofac Surg
JT - The Journal of craniofacial surgery
JID - 9010410
SB - D
MH - Adult
MH - Aged
MH - Dacryocystorhinostomy/*methods
MH - Endoscopy/*methods
MH - Ethmoid Sinus/surgery
MH - Female
MH - Follow-Up Studies
MH - Granulation Tissue/surgery MH - Humans
MH - Lacrimal Apparatus Diseases/surgery
MH - Lacrimal Duct Obstruction/surgery
MH - Male
MH - Middle Aged
MH - Nasal Septum/surgery
MH - Reoperation
MH - Retrospective Studies
MH - Tissue Adhesions/surgery
MH - Treatment Outcome
MH - Turbinates/surgery
MH - Young Adult
EDAT- 2010/12/02 06:00
MHDA- 2011/06/03 06:00
CRDT- 2010/12/02 06:00
AID - 10.1097/SCS.0b013e3181f3c6c1 [doi]
AID - 00001665-201011000-00011 [pii]
PST - ppublish
SO - J Craniofac Surg. 2010 Nov;21(6):1706-8.
PMID- 21280534
OWN - NLM
STAT- MEDLINE
DA - 20110201
DCOM- 20110519 IS - 0125-2208 (Print)
IS - 0125-2208 (Linking)
VI - 93 Suppl 6
DP - 2010 Nov
TI - Probing and syringing with 3% solution of NaCl and/or 0.2 mg/ml mitomycin-C in
nasolacrimal duct obstruction patients.
PG - S197-202
AB - OBJECTIVE: To compare the efficacy of lacrimal probing and syringing among 3%
solution of Sodium Chloride and/or 0.2 mg/ ml Mitomycin-C as an adjunctive
medication. DESIGN: A prospective, randomized, 2 by 2 factorial design study.
MATERIAL AND METHOD: Forty-eight of nasolacrimal duct obstruction patients with
epiphora symptom were randomly assigned to receive either Normal Saline Solution
or 3% solution of Sodium Chloride or 0.2 mg/ml Mitomycin-C solution or combined
3% solution of Sodium Chloride with 0.2 mg/ml Mitomycin-C solution, during office
probing and syringing. The intervention was performed repeatedly at week 0, weeks
2 and 4. An assessment of epiphora with Visual Analogue Scale were evaluated at
week 0, weeks 2, 4, 8 and 12. RESULTS: Probing and syringing was successfully
reducing epiphora symptom. Mitomycin-C group showed a significant reduction in
mean difference of Visual Analogue Scale score compared with Normal Saline
Solution group (2.85, 95% CI: 1.164-4.536, p < 0.001) and 3% Sodium Chloride
group (2.175, 95% CI: 0.489-3.861, p < 0.01). No complication or adverse event
was found. CONCLUSION: 0.2 mg/ml Mitomycin-C solution of was the most effective
medication for office probing and syringing in reducing epiphora symptom in
nasolacrimal duct obstruction patients.
AD - Department of Ophthalmology, Phramongkutklao College of Medicine, Bangkok, Thailand. [email protected]
FAU - Choontanom, Raveewan
AU - Choontanom R
LA - eng
PT - Journal Article
PT - Randomized Controlled Trial
PT - Research Support, Non-U.S. Gov't
PL - Thailand
TA - J Med Assoc Thai
JT - Journal of the Medical Association of Thailand = Chotmaihet thangphaet
JID - 7507216
RN - 0 (Antibiotics, Antineoplastic)
RN - 50-07-7 (Mitomycin)
RN - 7647-14-5 (Sodium Chloride)
SB - IM
MH - Adult
MH - Aged
MH - Antibiotics, Antineoplastic/*administration & dosage
MH - Female
MH - Humans
MH - Lacrimal Duct Obstruction/*therapy
MH - Male
MH - Middle Aged
MH - Mitomycin/*administration & dosage
MH - Nasolacrimal Duct/*surgery MH - Pain Measurement
MH - Prospective Studies
MH - Sodium Chloride/therapeutic use
MH - Syringes
MH - Therapeutic Irrigation/*methods
MH - Treatment Outcome
EDAT- 2011/02/02 06:00
MHDA- 2011/05/20 06:00
CRDT- 2011/02/02 06:00
PST - ppublish
SO - J Med Assoc Thai. 2010 Nov;93 Suppl 6:S197-202.
PMID- 21121125
OWN - NLM
STAT- MEDLINE
DA - 20101201
DCOM- 20110110
IS - 0023-2157 (Print)
IS - 0023-2157 (Linking)
VI - 112
IP - 7-9
DP - 2010
TI - [Treatment of nasolacrimal duct obstruction with probing in children younger than
4 years].
PG - 221-2 AB - PURPOSE: To evaluate the efficacy of nasolacrimal duct probing as the treatment
of nasolacrimal duct obstruction in children younger than 4 years. MATERIAL AND
METHODS: A total amount of 320 eyes in 275 children 4 to 48 months old, receiving
nasolacrimal duct probing were enrolled in a retrospective study. The patients
were divided into 4 groups depends on age: I group--4-12 months, II group--12-24
months, III group--24-36 months and IV group--36-48 months. RESULTS: The
percentage of efficient duct probing was: in I group--84%, in II group--79%, in
III group--78% and in IV group--59%. CONCLUSIONS: In children 4 to 36 months old,
probing is a successful treatment of nasolacrimal duct obstruction with no
decline in treatment success with increasing age.
AD - Z Kliniki Okulistyki Dzieciecej z Osodkiem Leczenia Zeza Uniwersytetu Medycznego
w Bialymstoku. [email protected]
FAU - Mrugacz, Malgorzata
AU - Mrugacz M
FAU - Sielicka, Danuta
AU - Sielicka D
FAU - Bakunowicz-Lazarczyk, Alina
AU - Bakunowicz-Lazarczyk A
LA - pol
PT - Comparative Study
PT - English Abstract
PT - Journal Article
TT - Leczenie niedroznosci drog lzowych za pomoca sondowania drog lzowych u dzieci w
wieku ponizej 4 lat.
PL - Poland TA - Klin Oczna
JT - Klinika oczna
JID - 0376614
SB - IM
MH - Child, Preschool
MH - Female
MH - Follow-Up Studies
MH - Humans
MH - Infant
MH - Lacrimal Duct Obstruction/*congenital/*surgery
MH - Male
MH - Nasolacrimal Duct/*abnormalities/*surgery
MH - Ophthalmologic Surgical Procedures/methods
MH - Poland
MH - Therapeutic Irrigation/*methods
MH - Treatment Outcome
EDAT- 2010/12/03 06:00
MHDA- 2011/01/11 06:00
CRDT- 2010/12/03 06:00
PST - ppublish
SO - Klin Oczna. 2010;112(7-9):221-2.