Vol. 114 No. 4 October 2012 SOBEP Oral Papers HETEROTOPIC GASTROINTESTINAL MUCOSA IN Bladder cancer is one of the most common cancers world- ORAL CAVITY Martins F1, Milani B2, Jorge WA, Gallottini wide. Oral bladder cancer metastases are unusual and occurred M3, Sousa S - 1UNIVERSITY OF SAO PAULO - ORAL frequently in the jawbones. This study describes case of a 28 PATHOLOGY, 2UNIVERSITY OF SAO PAULO - ORAL years-old male patient presenting with a symptomatic mouth SURGERRY, 3UNIVERSITY OF SAO PAULO - ORAL PA- lesion which had developed over a period of 20 days. In medical THOLOGY history the patient reported a bladder cancer treatment in 2009. Heterotopic gastrointestinal mucosa (HGM) is a rare entity The clinical exam revealed an extensive nodular lesion in the occurring more frequently in male infants. Floor of the mouth and right lower alveolar ridge, extending to buccal mucosa with tongue are the most common affected sites in oral cavity. Histo- erythematous and ulcerative surface. Incisional biopsy was done logically, HGM can be cystic or solid type, resembling gastric, followed by histopathological analysis to establish the definitive intestinal or colonic mucosa. A 35-year old man was referred for diagnosis. The histopathological aspects revealed an undifferen- diagnosis of a red, painless mass in the tongue (2.0 cm), which tiated malignant lesion. An immunohistochemical panel (AE1/ the patient presented since childhood. After an incisional biopsy, AE3, CK7, CK20, CK9, CK10, p63, s-100, HMB-45, desmine, the specimen revealed gastric glandular type tissue lined by actin, Factor VIII, CD-34, vimentin and CD-31) were realized. pseudostratified columnar epithelium, showing crypts and fundic The diagnosis of infiltrative high grade bladder carcinoma was glands. Submucosa exhibited gland ducts and the glands at the established. The patient was referred to head and neck surgeon to base of the crypt had cystic appearance. The cystic glands ex- the oral lesion treatment. tended into the underlying smooth muscle. Immunohistochemis- try revealed immunoreactivity for cytokeratins 7, 8 and 18 and XERODEMA PIGMENTOSUM: CASE REPORT Ribeiro SMA. Final diagnosis of HGM was made and the lesion was CMB1, Ferreira SM2, Peixoto FB3, Mikami JR4, Oliveira CB, surgically removed without margins. The patient has been fol- Leandro JF, Lima ALO3 - 1CENTRO UNIVERSITÁRIO CES- lowed for one year with no recurrences. MAC - PATOLOGIA BUCAL, 2CENTRO UNIVERSITÁRIO CESMAC - ESTOMATOLOGIA, 3CENTRO UNIVERSI- OSSEOUS CHORISTOMAS IN THE MASSETER MUSCLE TÁRIO CESMAC, 4CENTRO UNIVERSITÁRIO CESMAC - Amorim RFB1, Rosa EA1, Barbosa IM2, Cortez ALV3, Lawall CIRURGIA BUCO-MAXILO-FACIAL MA, Macedo SB3 - 1UNIVERSIDADE DE BRASÍLIA - PRO- Xerodema pigmentosum (XP) is a genodermatosis charac- GRAMA DE PÓS-GRADUAÇÃO EM CIÊNCIAS MÉDICAS, terized by photosensitivity and development of squamous cancers 2HOSPITAL UNIVERSITÁRIO DA UNB - PROGRAMA DE in young patients. XP is a genetic condition due to absence of RESIDÊNCIA MULTIPROFISSIONAL EM SAÚDE, 3UNI- repair in DNA defects resulted from ultra-violet radiation (UVR). VERSIDADE DE BRASÍLIA - CENTRO DE CIRURGIA E People with XP are more sensitive to UVR and have a greater TRAUMATOLOGIA BUCO-MAXILO-FACIAL risk to develop head-and-neck-skin-cancers compared to normal Osseous choristoma is a rare condition of the oral cavity individuals. XP-patients are diagnosed before 20-years-old and occurring usually in the posterior third of tongue. It is a mass of commonly show pre-malignant or malignant skin lesions. Com- normal bony structure with mature cells in an abnormal position. monly, squamous lesions show fast growing, thus the early The aim of the present work is to report a case of a 32-years-old detection of XP is useful to reduce morbidity and mortality of woman admitted at Maxillofacial Surgery Department for eval- XP-patients. The study reports a case of XP affecting a female uation of painful hardened nodules present among the left mas- patient, 5-years-old, dark skin, referred to a Dentistry School seter muscle. Spheroids calcifications laterally located to the presenting a nodule in the lower lip during 3 months with mandibular ramus could be observed on computed tomography. ulcerated surface and multiples actinic keratosis. After incisional Under general anesthesia, seven hard structures were removed biopsy, microscopic analysis revealed an oral squamous cell through a submandibular access, the largest measuring 0.7 ϫ 0.4 carcinoma. Patient was referred to surgical treatment and she is cm. Histopathological examination revealed vital bone, osteo- under follow-up during one-year. cytes, incremental lines, and bone marrow, supporting the clinical diagnose. After 12 months of follow up there was no clinical or EOSINOPHILIC ULCER AFFECTING THE DORSUM OF radiographic sign of recurrence. This case is the second described 1 1 1 choristoma on masticatory muscles and also differs from osseous THE TONGUE Fonseca FP , Flores IL , Coletta RD , 1 1 1 choristomas in general by the presence of pain. Almeida OP , Santos-Silva AR - FACULDADE DE ODON- TOLOGIA DE PIRACICABA - UNIVERSIDADE ESTADUAL DE CAMPINAS - DEPARTAMENTO DE DIAGNOSTICO ORAL METHASTASIS OF BLADDER CANCER: REPORT ORAL 1 1 OF A RARE LESION Curra M , Medella Júnior F , Martins Eosinophilic ulcer of the oral mucosa is a self-limited con- 1 2 1 1 MD , Martins MAT , Carrard VC , Sant’Ana Filho M , Mu- dition first described in adults by Popoff in 1956. The pathogenic 2 1 nerato MC - UNIVERSIDADE FEDERAL DO RIO mechanisms implicated in its development remain poorly under- GRANDE DO SUL - PATOLOGIA BUCAL, 2HOSPITAL DE stood, but local trauma is the most reported etiologic factor. CLÍNICAS DE PORTO ALEGRE - SERVIÇO DE ESTOMA- Clinically, the eosinophilic ulcer usually manifests as a rapidly TOLOGIA developing solitary ulcer, with elevated borders, arising most e31 ORAL MEDICINE OOOO e32 Abstracts October 2012 commonly in the lateral surface of the tongue. Microscopically, a remains in clinical and radiological follow-up for 22 months poorly formed granulation tissue with a dense polymorphous without any changes associated to the affected area. In conclu- inflammatory infiltrate containing abundant eosinophils and ex- sion, Stafne’s defect should be also considered in the differential tending to the deeper structures is usually observed. The ulcers diagnosis of anterior mandibular radiolucencies. commonly regress spontaneously in less than a month. The diagnosis of oral eosinophilic ulcer is usually difficult because UNUSUAL ORAL MANIFESTATIONS OF HISTOPLASMOSIS different processes may share similar clinical and histopatholog- Motta ACF1, Komesu MC1, Guerrini LB1, Shatetich C2, ical appearances. Therefore, the objective of this paper is to Roselino AMF3 - 1FACULDADE DE ODONTOLOGIA DE report a case of eosinophilic ulcer of the dorsum of the tongue RIBEIRÃO PRETO/USP - MORFOLOGIA, ESTOMATOLO- affecting a 64 year old male patient that following the incisional GIA E FISIOLOGIA, 2HOSPITAL DAS CLÍNICAS DE RI- biopsy revealed adequate remission. BEIRÃO PRETO - SERVIÇO DE PATOLOGIA, 3FAC- ULDADE DE MEDICINA DE RIBEIRÃO PRETO/USP - LINGUAL MANDIBULAR BONE DEPRESSION IN AN CLÍNICA MÉDICA/DIVISÃO DE DERMATOLOGIA 1 2 UNCOMMON LOCATION Pires FR , Espíndola CB ,Es- Histoplasmosis is a systemic fungal infection caused by the 2 3 4 1 píndola SHF , Miranda AMMA , Netto JNS - STATE UNI- Histoplasma capsulatum. Mucosal manifestations are uncom- VERSITY OF RIO DE JANEIRO - ORAL PATHOLOGY, mon, but, when present, they are usually associated with pulmo- 2 3 GENERAL DENTISTRY - PRIVATE PRACTICE, ESTÁCIO nary or chronic disseminated infection in immunocompromised DE SÁ UNIVERSITY - STOMATOLOGY AND ORAL AND patient. This case refers to a 29-year-old woman who presented MAXILLOFACIAL SURGERY, 4FEDERAL UNIVERSITY OF oral lesions, which had appeared 2 years before. She had reported RIO DE JANEIRO - ORAL PATHOLOGY contact with pigeon. On physical examination, a slightly painful Lingual mandibular bone depression (Stafne’s defect) mostly ulcerated lesion on the buccal gingiva and hard palate was affects the posterior mandible. Stafne’s defects on the anterior detected. Blood tests just revealed a mild anemia, whereas sero- region are rare, frequently posing difficulties on diagnosis. The logic tests for HIV, HBV, HCV, paracoccidioidomicosis, leish- aim of this study is to report a Stafne’s defect affecting the maniasis, tuberculosis, and syphilis were all negative. Counter- anterior mandible, discussing its main differential diagnostic immunoelectrophoresis test for histoplasmosis was positive (titer considerations. A 43-year-old male was referred for evaluation of 1:2). Chest X-ray was normal. Histopathological analysis indi- a well-defined radiolucent area on the anterior mandible in close cated a chronic inflammation with granulomas presenting yeast- association to the roots of the right canine and incisors, discov- like organisms. Isolation of H capsulatum provided the definitive ered during routine dental radiographic evaluation. Pulp tests diagnosis. Patient is on treatment with oral itraconazole (200mg/ revealed that all teeth in the area were vital and a cone-beam day) presenting remission of the lesions. This case represents an computed tomography scan showed a lingual depression in the interesting demonstration that histoplasmosis may cause unusual area. Final diagnosis was anterior Stafne’s defect and the patient oral presentation. OOOO ORAL ABSTRACT Volume 114, Number 4 Abstracts e33 SOBEP Free Oral