* OUR PARTNERSHIPS

Our approach to partnerships is different. We ensure that we meet unmet medical * Santen’s original interpretation of a passage from Zhongyong (The Doctrine of the Mean) needs and achieve faster access for patients by Confucius, meaning “exploring the secrets and mechanisms of nature in order to contribute to people’s health.” to treatments by working closely with companies, institutes and academia. By focusing on ophthalmology, Santen develops unique scientific knowledge and organizational capabilities that contribute to the well- being of patients, their loved ones and consequently to society.

OUR CORPORATE Our Principles SOCIAL RESPONSIBILITY Vision-drivenVision-driven

CustomerHarmony with PerspectiveSociety Our commitment to the ophthalmology community goes beyond our products. As part of the ophthalmology community, we believe CreativityCustomer andPerspective Innovation it is our responsibility to support patients and their loved ones, EmployeeCreativity andGrowthInnovation and take action to create a sustainable society and environment in accordance with Santen’s Values. HarmonyEmployee withGrowth Society OrganizationalOrganisational

Integrity and Trust Protecting the World’s Vision

CustomerCustomer-oriented-oriented Thinking Provision of Fair business Respect for Occupational Environmental Social appropriate products practices human rights health and safety conservation contribution and services Expertise OUR COMMITMENT TO EYE CARE Innovation WILL ALWAYS ENDURE Collaboration and Cooperation Individual

SEE MORE AT WWW.SANTEN.EU Corporate Leaflet Santen EMEA

Job code: NP-SANTEN-EMEA-0111 Date of preparation: May 2019 NEARLY 130 YEARS OUR BREADTH OF MEDICINES: COMMITMENT TO PATIENT VISION GLOBAL AT A GLANCE OCULAR HEALTH

Our current treatments cover a number Heritage of therapeutic areas: We have been committed to ophthalmology for Dry Eye & Ocular Surface Disorders almost 130 years Glaucoma Cataract

€€1.8231.662 Billion 3,600+4,070+3,600+ 3029 Subsidiaries29 Subsidiaries4 R&D Centres 4 R&D Centres Infection globalglobal revenue*revenue* staffstaff globally globallystaff globally (Asia, Europe, (Asia,U.S.) Europe, U.S.)Nara (),Nara (Japan), Tampere (), Breadth of medicines Tampere (Finland),Evry (), Emeryville (U.S.) Allergy Our R&D is driven by 2,070+1,690+1,690+ Evry (France), outside Japan Singular focus patient needs. We strive outside Japan Emeryville (U.S.) 4 Manufacturing sites Retina (in development) Our specialised approach to improve patients lives Noto (Japan), Shiga (Japan), 4 ManufacturingSuzhou sites (), Tampere (Finland) enables us to concentrate Noto (Japan), Shiga (Japan), on ocular health Suzhou (China), Tampere (Finland) EMEA AT A GLANCE Partnerships We work with the com- OUR PRESENCE munity to understand the unmet need and provide solutions Our products are sold in over 60 countries

Santen UK Limited Chongqing Santen Kerui Pharmaceutical Co., Ltd. Santen Holdings U.S. Inc. Santen S.A.S. Santen Pharmaceutical (China) Co., Ltd./ Santen Inc. Santen SA, The Branch Santen Pharmaceutical Advanced Vision Science, Inc. Santen Holdings EU B.V. Sales and Marketing (Suzhou) Co., Ltd. SantenPharma AB Santen Pharmaceutical €€282200€ 1.662Million Billion turnover 600+730+ 3,600+ Presence in29 Subsidiaries2 R&D Centres 4 R&D Centres Santen Oy Korea Co., Ltd. “We are an ophthalmology company, focused only on delivering global(28.5bn,(36.2bn, revenue* Yen)* employeesstaff globally approximately(Asia, Europe, U.S.)Santen Oy (Finland)Nara (Japan),& Tampere (Finland), ophthalmic innovation to our customers – and ultimately patients – 50 countries Santen S.A.S S.A.S. (France) Evry (France), Emeryville (U.S.) 1,690+ Tampere Plant in Europe, the Middle East and Africa. This unique dedication allows outside Japan 4 Manufacturing sites SANTEN LIMITED Manufacturing sitesite: LIABILITY COMPANY Noto (Japan), Shiga (Japan), us to ensure our R&D, commercial operations, manufacturing, regu- Santen Oy Products exported Santen GmbH to Europe, MiddleSuzhou East, (China), Tampere (Finland) Santen S.r.l. latory and all other functions at Santen focus exclusively on bringing Africa and U.S. Santen SA Santen Pharmaceutical Santen Canada Inc. the best products and solutions to market. , S.L. Santen Ventures, Inc. Suzhou Plant Noto Plant InnFocus, Inc. Claire FINANCIAL TARGETS FOR 2020 Co., Ltd. Shiga Product By leveraging this expertise as a specialised ophthalmic company, Supply Center we can best understand our customers’ and patients’ needs, Santen Corporate Of total sales to be made Headquarters making us a major player and partner to many ophthalmologists % overseas in fiscal yearyear 20202020 Nara Research and 40-5040-50 Development Center in Europe, Middle East and Africa.” Santen Eye Care Co., Ltd. Position Santen Business Services Co., Ltd. Top 3 globally Santen Private Limited Luis Iglesias, Head of Santen EMEA* SANTEN () CO., LTD. Ho Chi Minh Representative Of ce Santen Pharmaceutical Co., Ltd. In Japan SANTEN PHARMA SDN. BHD. SANTEN PHARMACEUTICAL (HONG KONG) LIMITED *Europe Middle East Africa #1 and Asia * Data FY ended March 31, 2019 (f/x rate 1€ = 128.38 ¥) Santen Pharmaceutical Asia Pte. Ltd. SANTEN INC.