Anti-PAG1 Monoclonal Antibody, Clone NFN-366 (CABT-BL5342) This Product Is for Research Use Only and Is Not Intended for Diagnostic Use

Anti-PAG1 monoclonal antibody, clone NFN-366 (CABT-BL5342) This product is for research use only and is not intended for diagnostic use.

PRODUCT INFORMATION

Product Overview Mouse monoclonal antibody to Human PAG1.

Specificity This antibody is specific for CSK Binding Protein

Immunogen Recombinant intracellular fragment, corresponding to amino acids 97-432 of Human CSK Binding Protein.

Isotype IgG2a

Source/Host Mouse

Species Reactivity Human

Clone NFN-366

Conjugate Unconjugated

Format Liquid

Concentration 1.000 mg/ml

Size 100 μg

Buffer PBS, pH 7.4

Preservative 15mM Sodium Azide

Storage Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.

BACKGROUND

Introduction The protein encoded by this gene is a type III transmembrane adaptor protein that binds to the tyrosine kinase csk protein. It is thought to be involved in the regulation of T cell activation. [provided by RefSeq, Jul 2008]

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]

Entrez Gene ID 55824

Protein Refseq NP_060910

UniProt ID Q9NWQ8

Chromosome Location 8q21.13

Pathway Adaptive Immune System, organism-specific biosystem; BCR signaling pathway, organism- specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; GAB1 signalosome, organism-specific biosystem; Immune System, organism-specific biosystem; Phosphorylation of CD3 and TCR zeta chains, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by EGFR, organism-specific biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem; TCR sig

Function SH2 domain binding; SH3/SH2 adaptor activity; protein binding;

45-1 Ramsey Road, Shirley, NY 11967, USA Email: [email protected]